Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12m01f
(644 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component sub... 177 2e-43
UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-... 165 6e-40
UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,... 165 1e-39
UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alph... 161 1e-38
UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component sub... 157 3e-37
UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component sub... 123 3e-27
UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=... 122 6e-27
UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component sub... 122 6e-27
UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component sub... 120 3e-26
UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whol... 119 5e-26
UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamid... 115 1e-24
UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 112 6e-24
UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 107 3e-22
UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component sub... 107 3e-22
UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alp... 105 1e-21
UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alp... 105 1e-21
UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alp... 103 4e-21
UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutacea... 101 2e-20
UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, al... 100 3e-20
UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37; Bacteria|... 99 5e-20
UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, al... 96 6e-19
UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALP... 96 6e-19
UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 95 1e-18
UniRef50_Q1EGH8 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 95 1e-18
UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, al... 92 1e-17
UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflex... 90 5e-17
UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alp... 87 3e-16
UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|R... 85 1e-15
UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidotherm... 85 1e-15
UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component sub... 85 1e-15
UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 al... 85 2e-15
UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1 ... 84 3e-15
UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa ... 82 1e-14
UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|R... 81 3e-14
UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3; Prote... 80 5e-14
UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 80 5e-14
UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8; Chla... 79 9e-14
UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 79 9e-14
UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E... 78 2e-13
UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3; Prote... 78 2e-13
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 76 6e-13
UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n... 76 6e-13
UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase (Lipoam... 76 8e-13
UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 76 8e-13
UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase alpha-s... 75 1e-12
UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3; Actin... 75 1e-12
UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit (... 75 1e-12
UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha... 75 2e-12
UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 75 2e-12
UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1; Chlor... 74 3e-12
UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2; Bacte... 74 3e-12
UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomon... 72 1e-11
UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 71 3e-11
UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1; Proch... 70 4e-11
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 66 7e-10
UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 66 9e-10
UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 66 9e-10
UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 66 9e-10
UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridiu... 64 2e-09
UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1; ... 64 3e-09
UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2; Alphap... 64 4e-09
UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2; Rhodo... 63 6e-09
UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 62 8e-09
UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketola... 62 8e-09
UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 62 8e-09
UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=... 62 1e-08
UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc... 61 3e-08
UniRef50_Q0ET31 Cluster: Dehydrogenase, E1 component; n=1; Therm... 60 6e-08
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 42 3e-07
UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12; Bacteria|... 57 3e-07
UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=... 57 3e-07
UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and ... 56 6e-07
UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4; Actinomyce... 56 1e-06
UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1; R... 56 1e-06
UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 54 4e-06
UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 52 9e-06
UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1; Novos... 52 2e-05
UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n... 51 3e-05
UniRef50_Q9K3H0 Cluster: Putative pyruvate dehydrogenase alpha s... 50 6e-05
UniRef50_Q1NYL5 Cluster: Pyruvate dehydrogenase E1 component alp... 49 1e-04
UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 48 1e-04
UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway sig... 48 2e-04
UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid dehydrog... 48 3e-04
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 47 3e-04
UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase; ... 47 3e-04
UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7; Mycoba... 47 4e-04
UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, al... 46 8e-04
UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 46 0.001
UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, al... 45 0.001
UniRef50_UPI0000384B37 Cluster: COG1071: Pyruvate/2-oxoglutarate... 45 0.002
UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 45 0.002
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 45 0.002
UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3; Actinomyce... 44 0.002
UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomon... 42 0.013
UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 42 0.017
UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n... 41 0.022
UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alp... 40 0.051
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 40 0.068
UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 40 0.068
UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha subu... 39 0.12
UniRef50_A2C5U8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 39 0.12
UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC ... 38 0.16
UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22; Prot... 38 0.16
UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate... 38 0.27
UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent dehydr... 37 0.36
UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 36 0.63
UniRef50_A0QB51 Cluster: Dehydrogenase E1 component superfamily ... 36 0.63
UniRef50_UPI00004D6EAE Cluster: Ras and Rab interactor 1 (Ras in... 36 0.84
UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 36 0.84
UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alp... 36 1.1
UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum... 36 1.1
UniRef50_A3DC57 Cluster: Methyl-accepting chemotaxis sensory tra... 34 2.6
UniRef50_A2FVJ6 Cluster: DnaK protein; n=1; Trichomonas vaginali... 34 3.4
UniRef50_UPI0000F2D933 Cluster: PREDICTED: similar to doublecort... 33 4.5
UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 33 4.5
UniRef50_A7S2A1 Cluster: Predicted protein; n=1; Nematostella ve... 33 4.5
UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid dehydrog... 33 4.5
UniRef50_A1D894 Cluster: Mating-type protein, putative; n=1; Neo... 33 4.5
UniRef50_Q9Y149 Cluster: Mediator of RNA polymerase II transcrip... 33 5.9
UniRef50_Q6QXE3 Cluster: ORF24; n=1; Agrotis segetum granuloviru... 33 7.8
UniRef50_Q23HD3 Cluster: Cyclic nucleotide-binding domain contai... 33 7.8
UniRef50_A2DM79 Cluster: Putative uncharacterized protein; n=1; ... 33 7.8
>UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha type I, mitochondrial precursor; n=10;
cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha type I, mitochondrial precursor
- Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Length = 396
Score = 177 bits (430), Expect = 2e-43
Identities = 83/142 (58%), Positives = 105/142 (73%)
Frame = +2
Query: 197 ITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRR 376
+ V+ V+A + + ++ EATF+ KP+KLHKLD GP + +T EDA+ Y Q+ +RR
Sbjct: 11 VPTVSPSVMAISVRLAST-EATFQTKPFKLHKLDSGPDINVHVTKEDAVHYYTQMLTIRR 69
Query: 377 IETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLG 556
+E+A+GNLYKEK +RGFCHLYSGQEA AVG +AAM D+ +TAYRCHGWTYL G SV
Sbjct: 70 MESAAGNLYKEKKVRGFCHLYSGQEACAVGTKAAMDAGDAAVTAYRCHGWTYLSGSSVAK 129
Query: 557 VLSELTGRRTGCSRGKGGSMHL 622
VL ELTGR TG GKGGSMH+
Sbjct: 130 VLCELTGRITGNVYGKGGSMHM 151
>UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-PA
- Drosophila melanogaster (Fruit fly)
Length = 479
Score = 165 bits (402), Expect = 6e-40
Identities = 73/115 (63%), Positives = 89/115 (77%)
Frame = +2
Query: 278 YKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 457
+K + L+ GP L+ EDAL +Y Q+ LRR ET +GN YKE+ IRGFCHLY+GQEAV
Sbjct: 43 FKCYDLENGPTMDVELSREDALTMYTQMLELRRFETVAGNYYKERKIRGFCHLYNGQEAV 102
Query: 458 AVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
AVGM+ +R DSVITAYRCH WTYLMGVS+ +++EL G RTGCSRGKGGSMH+
Sbjct: 103 AVGMKQRLRSCDSVITAYRCHAWTYLMGVSLYEIMAELFGVRTGCSRGKGGSMHM 157
>UniRef50_UPI0000E4A5CB Cluster: PREDICTED: hypothetical protein,
partial; n=2; Strongylocentrotus purpuratus|Rep:
PREDICTED: hypothetical protein, partial -
Strongylocentrotus purpuratus
Length = 378
Score = 165 bits (400), Expect = 1e-39
Identities = 70/116 (60%), Positives = 93/116 (80%)
Frame = +2
Query: 275 PYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 454
P+KLHKL++GP ++ LT ++AL Y ++ +RR+ETA+ LYK K +RGFCHLYSGQEA
Sbjct: 165 PFKLHKLEEGPKKTSVLTKDEALDYYHKMQTIRRMETAAATLYKSKEVRGFCHLYSGQEA 224
Query: 455 VAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
AVG+ + + D+VITAYR HGW YL GV++ GVL+ELTGRRTGC++GKGGSMH+
Sbjct: 225 CAVGISSVLTPDDAVITAYRAHGWAYLRGVTLHGVLAELTGRRTGCAKGKGGSMHM 280
>UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alpha
1; n=3; Tetrapoda|Rep: Pyruvate dehydrogenase
(Lipoamide) alpha 1 - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 369
Score = 161 bits (392), Expect = 1e-38
Identities = 75/162 (46%), Positives = 105/162 (64%)
Frame = +2
Query: 137 IIDKMSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATS 316
++ +S+++ A+ + +VA+ EATF+IK +H+L++GP T
Sbjct: 4 MLSLLSRVLKGPAQKPVTGAANEAVRVMVASRNYADFASEATFDIKKCDVHRLEEGPPTQ 63
Query: 317 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 496
A LT E L+ Y + +RR+E S LYK+KIIRGFCHLY GQEA VG+ AA+ D
Sbjct: 64 AVLTREQGLQYYRTMQTIRRMELKSDQLYKQKIIRGFCHLYDGQEACCVGLEAAINPTDH 123
Query: 497 VITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+ITAYR HG++Y GVSV +L+ELTGRR GC++GKGGSMH+
Sbjct: 124 LITAYRAHGYSYTRGVSVKEILAELTGRRGGCAKGKGGSMHM 165
>UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, somatic form, mitochondrial precursor;
n=110; cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha, somatic form, mitochondrial
precursor - Homo sapiens (Human)
Length = 390
Score = 157 bits (380), Expect = 3e-37
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, mitochondrial precursor; n=34;
Dikarya|Rep: Pyruvate dehydrogenase E1 component subunit
alpha, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 420
Score = 123 bits (297), Expect = 3e-27
Identities = 58/106 (54%), Positives = 74/106 (69%)
Frame = +2
Query: 305 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 484
P S + L++Y+ + I+RR+E A LYK K IRGFCHL GQEA+AVG+ A+
Sbjct: 70 PDLSYETSKATLLQMYKDMVIIRRMEMACDALYKAKKIRGFCHLSVGQEAIAVGIENAIT 129
Query: 485 DADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
DS+IT+YRCHG+T++ G SV VL+EL GRR G S GKGGSMHL
Sbjct: 130 KLDSIITSYRCHGFTFMRGASVKAVLAELMGRRAGVSYGKGGSMHL 175
>UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=5;
Intramacronucleata|Rep: Pyruvate dehydrogenase E1
component - Tetrahymena thermophila SB210
Length = 429
Score = 122 bits (295), Expect = 6e-27
Identities = 64/153 (41%), Positives = 87/153 (56%), Gaps = 1/153 (0%)
Frame = +2
Query: 173 AKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPA-TSATLTSEDALKL 349
AK + V KY+ T ++ Y+ LD T +T T E+ LKL
Sbjct: 41 AKLMISKFFNPVAGKTFNRLNKYAFSS-VTINLEGYQTKMLDGFKLPTQSTATKEELLKL 99
Query: 350 YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWT 529
Y+ + ++R+IE A LYK++ IRGFCHLY GQEAV G+ AA D++ITAYRCH
Sbjct: 100 YKDMNVMRKIELACDKLYKQREIRGFCHLYDGQEAVISGIEAACNLEDAIITAYRCHCHA 159
Query: 530 YLMGVSVLGVLSELTGRRTGCSRGKGGSMHLVR 628
Y G + +++EL GR+TG + GKGGSMH R
Sbjct: 160 YTRGDTPHQIIAELMGRKTGSTGGKGGSMHFYR 192
>UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=62; Bacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 348
Score = 122 bits (295), Expect = 6e-27
Identities = 58/111 (52%), Positives = 73/111 (65%)
Frame = +2
Query: 290 KLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 469
K D T A + ED LK Y ++ ++RR E +G LY I GFCHLY GQEAV VGM
Sbjct: 20 KKDFAGGTIAEFSKEDDLKAYREMLLIRRFEEKAGQLYGMGFIGGFCHLYIGQEAVVVGM 79
Query: 470 RAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+ A+++ D VIT YR HG G+S GV++ELTGRR G S+GKGGSMH+
Sbjct: 80 QLALKEGDQVITGYRDHGHMLACGMSARGVMAELTGRRGGLSKGKGGSMHM 130
>UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor; n=33; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 393
Score = 120 bits (289), Expect = 3e-26
Identities = 57/118 (48%), Positives = 78/118 (66%)
Frame = +2
Query: 275 PYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEA 454
P+ H L + P+ S +SE+ L + + +RR+E A+ +LYK K+IRGFCHLY GQEA
Sbjct: 43 PFTSH-LCESPSRSVETSSEEILAFFRDMARMRRMEIAADSLYKAKLIRGFCHLYDGQEA 101
Query: 455 VAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLVR 628
+AVGM AA+ D++IT+YR H G ++ SEL GR+TGCS GKGGSMH +
Sbjct: 102 LAVGMEAAITKKDAIITSYRDHCTFIGRGGKLVDAFSELMGRKTGCSHGKGGSMHFYK 159
>UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10102,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 491
Score = 119 bits (287), Expect = 5e-26
Identities = 54/102 (52%), Positives = 71/102 (69%)
Frame = +2
Query: 284 LHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAV 463
LH+L++GP A LT E L+ Y + +RR+E + LYK+KIIRGFCHLY GQEA A
Sbjct: 5 LHRLEEGPPEKAELTREQGLQYYRTMQTIRRMELKADQLYKQKIIRGFCHLYDGQEACAA 64
Query: 464 GMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG 589
G+ AA+ +D +ITAYR HG+T+ GVSV +L+ELTG G
Sbjct: 65 GIEAAITPSDHLITAYRAHGYTFTRGVSVKEILAELTGETGG 106
>UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamide
<=> S-Acetyldihydrolipoamide + CO2; n=3; Ascomycota|Rep:
Catalytic activity: Pyruvate + Lipoamide <=>
S-Acetyldihydrolipoamide + CO2 - Aspergillus niger
Length = 403
Score = 115 bits (276), Expect = 1e-24
Identities = 55/115 (47%), Positives = 76/115 (66%)
Frame = +2
Query: 278 YKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAV 457
++ + LD P + T T +LY ++++RR+E A+ LYKE+ IRGFCHL +GQEAV
Sbjct: 54 FETYNLDPPPYSLET-TKSQLKQLYYDMSLIRRMELAADKLYKEQKIRGFCHLSTGQEAV 112
Query: 458 AVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
AVG+ + D VITAYR HG+T + G SV ++ EL GRR G GKGGS+H+
Sbjct: 113 AVGVEHGISPEDKVITAYRAHGFTLMRGGSVKSIIGELLGRRDGICHGKGGSVHM 167
>UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=6; Spirotrichea|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Euplotes sp. BB-2004
Length = 389
Score = 112 bits (270), Expect = 6e-24
Identities = 52/119 (43%), Positives = 75/119 (63%), Gaps = 1/119 (0%)
Frame = +2
Query: 266 EIKPYKLHKLDQGPA-TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYS 442
E+ +K+H++++ T AT T + L Y+ + ++RR+E S LYK K IRGFCHLY
Sbjct: 30 ELPKFKVHRIEESELPTKATTTKSELLNYYKDMALMRRVEIVSDMLYKNKWIRGFCHLYD 89
Query: 443 GQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 619
GQE++ VGM AA+ D +I AYR H G + +++E+ R TG S+GKGGSMH
Sbjct: 90 GQESITVGMEAALTMEDHIINAYRDHTTAMGRGHTSYEIIAEMMQRSTGSSKGKGGSMH 148
>UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Trypanosoma cruzi|Rep: Pyruvate dehydrogenase E1
alpha subunit - Trypanosoma cruzi
Length = 378
Score = 107 bits (256), Expect = 3e-22
Identities = 55/121 (45%), Positives = 73/121 (60%), Gaps = 4/121 (3%)
Frame = +2
Query: 272 KPYKLHKL---DQGPA-TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLY 439
KP+KLH D P T+AT +E K E + +RR+E+ YK K IRGFCHLY
Sbjct: 21 KPFKLHTAGRDDVPPVPTTATYDTEQMKKCLEMMFRIRRMESLCDQSYKLKKIRGFCHLY 80
Query: 440 SGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 619
GQEA+ VGM + D ++TAYR H W + G + V +E+ G+ GCS+GKGGSMH
Sbjct: 81 IGQEAIPVGMENVLTLEDLIVTAYRDHAWYIVRGGTPGEVFAEMFGKEGGCSKGKGGSMH 140
Query: 620 L 622
+
Sbjct: 141 M 141
>UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Proteobacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Zymomonas
mobilis
Length = 354
Score = 107 bits (256), Expect = 3e-22
Identities = 52/102 (50%), Positives = 69/102 (67%), Gaps = 1/102 (0%)
Frame = +2
Query: 332 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA-DSVITA 508
E+ L+ Y ++ ++RR E G LY +I GFCHLY GQEAVAVG++AA++ DSVIT
Sbjct: 37 EELLEFYRRMLMIRRFEERCGQLYGLGLIAGFCHLYIGQEAVAVGLQAALQPGRDSVITG 96
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLVRTQ 634
YR HG G+ V++ELTGR +G S GKGGSMH+ T+
Sbjct: 97 YREHGHMLAYGIDPKIVMAELTGRASGISHGKGGSMHMFSTE 138
>UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=5; Euglenozoa|Rep: Pyruvate
dehydrogenase E1 component alpha subunit, putative -
Leishmania major
Length = 378
Score = 105 bits (251), Expect = 1e-21
Identities = 57/139 (41%), Positives = 74/139 (53%), Gaps = 4/139 (2%)
Frame = +2
Query: 224 ATNAKYSTKKEATFEIKPYKLH---KLDQGPATSATLTSEDALKLYEQLTI-LRRIETAS 391
AT TK +P+KLH + D P + + + LK L +RR+E+
Sbjct: 5 ATRCLLDTKTVPLKPQRPFKLHTAGRTDMAPLPTQAVYDAEQLKQSLALMFRIRRMESLC 64
Query: 392 GNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSEL 571
YK K IRGFCHLY GQEA+ GM + D +IT YR HGW G V +E+
Sbjct: 65 DQSYKLKKIRGFCHLYIGQEAIPAGMENVLTFEDPIITGYRDHGWYISRGGKPEDVFAEM 124
Query: 572 TGRRTGCSRGKGGSMHLVR 628
GR+ GCS+GKGGSMH+ R
Sbjct: 125 FGRQGGCSKGKGGSMHMYR 143
>UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=1; Aspergillus fumigatus|Rep:
Pyruvate dehydrogenase E1 component alpha subunit,
putative - Aspergillus fumigatus (Sartorya fumigata)
Length = 360
Score = 105 bits (251), Expect = 1e-21
Identities = 46/84 (54%), Positives = 63/84 (75%)
Frame = +2
Query: 371 RRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSV 550
+R+E A+ LYK+K IRGFCHL +GQEAVAVG+ + D +ITAYR HG+T++ G S+
Sbjct: 81 QRLEIAADALYKQKKIRGFCHLSTGQEAVAVGIEYGISKEDKLITAYRSHGFTFMRGGSI 140
Query: 551 LGVLSELTGRRTGCSRGKGGSMHL 622
+ ++ EL GR+ G S GKGGSMH+
Sbjct: 141 MSIVGELLGRQDGISHGKGGSMHM 164
>UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=4; Bacteria|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 334
Score = 103 bits (247), Expect = 4e-21
Identities = 49/107 (45%), Positives = 66/107 (61%)
Frame = +2
Query: 302 GPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 481
G + L+ E + Y + ++RR E +G LY +I GFCHLY GQEAV VG+ M
Sbjct: 9 GRSNGPALSPETMKRAYRDMLLVRRFEEKAGQLYGMGLIGGFCHLYIGQEAVVVGIGLNM 68
Query: 482 RDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+ D IT+YR HG + G++ GV++ELTGR G S GKGGSMH+
Sbjct: 69 KQGDKSITSYRDHGQMLVAGMTPRGVMAELTGRSGGYSHGKGGSMHM 115
>UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate dehydrogenase - Opitutaceae
bacterium TAV2
Length = 365
Score = 101 bits (241), Expect = 2e-20
Identities = 50/102 (49%), Positives = 65/102 (63%)
Frame = +2
Query: 314 SATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDAD 493
+A LT ++LY + +RR E S Y+ K I GF HLY GQEAVAVG + M + D
Sbjct: 28 NADLTPAARIELYRTMVRIRRFEERSLRAYQAKKIGGFLHLYIGQEAVAVGCCSLMGEHD 87
Query: 494 SVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 619
VITAYR HG +G+ +++EL G+ TGCS+GKGGSMH
Sbjct: 88 HVITAYRDHGHAIAVGMDTKALMAELYGKATGCSKGKGGSMH 129
>UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=1; Lentisphaera araneosa HTCC2155|Rep:
Dehydrogenase complex, E1 component, alpha subunit -
Lentisphaera araneosa HTCC2155
Length = 320
Score = 100 bits (240), Expect = 3e-20
Identities = 46/97 (47%), Positives = 64/97 (65%)
Frame = +2
Query: 332 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 511
E AL++ EQ+ +RR E Y++K I GFCH Y GQEAVAVG A + D+ +T+Y
Sbjct: 7 EKALQMLEQMIRVRRFEEGCLKSYQQKFITGFCHTYIGQEAVAVGAMAHLTPTDAYVTSY 66
Query: 512 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
RCH + G++ V++E+ G+ TGC RGKGGSMH+
Sbjct: 67 RCHAQGLIGGLTSREVMAEMFGKITGCVRGKGGSMHV 103
>UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37;
Bacteria|Rep: Pyruvate dehydrogenase - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 337
Score = 99 bits (238), Expect = 5e-20
Identities = 46/95 (48%), Positives = 65/95 (68%)
Frame = +2
Query: 338 ALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC 517
AL + + +RR+E LY E+ IRGF HLY G+EAVAVG A++ D+V+ YR
Sbjct: 21 ALAVLAGMLRIRRMEEKCAQLYGEQKIRGFLHLYIGEEAVAVGALRALQPQDNVVATYRE 80
Query: 518 HGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
HG L G+++ G+++E+ G+R GCSRG+GGSMHL
Sbjct: 81 HGHALLRGLAMNGIMAEMYGKREGCSRGRGGSMHL 115
>UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=5; Geobacter|Rep: Dehydrogenase complex, E1
component, alpha subunit - Geobacter sulfurreducens
Length = 325
Score = 96.3 bits (229), Expect = 6e-19
Identities = 47/102 (46%), Positives = 63/102 (61%)
Frame = +2
Query: 317 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 496
A L + LK++EQ+ + R E + Y + I GF HLYSGQEAVAVG AA+R D
Sbjct: 7 AILPDSELLKMHEQMVLSREFEESCAEQYTKGHITGFLHLYSGQEAVAVGATAALRKDDY 66
Query: 497 VITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+++AYR H + G V++EL G+ TG +GKGGSMHL
Sbjct: 67 ILSAYREHAQAIVRGAEPRRVMAELFGKATGMCKGKGGSMHL 108
>UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA
SUBUNIT; n=1; Encephalitozoon cuniculi|Rep: PYRUVATE
DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT -
Encephalitozoon cuniculi
Length = 349
Score = 96.3 bits (229), Expect = 6e-19
Identities = 43/97 (44%), Positives = 63/97 (64%)
Frame = +2
Query: 332 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 511
+ A+ +Y+Q+ +R ++ A YK K IRGFCHL GQE + + AM D D +++Y
Sbjct: 37 DKAVYIYKQMMRMRCMDEAMDREYKRKNIRGFCHLSIGQEGIYAALEYAM-DGDVAVSSY 95
Query: 512 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
RCHG Y+ G S+L ++ E+ GR+ G +GKGGSMHL
Sbjct: 96 RCHGIAYVTGCSILEIMGEVLGRQAGVCKGKGGSMHL 132
>UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 353
Score = 95.5 bits (227), Expect = 1e-18
Identities = 48/104 (46%), Positives = 65/104 (62%), Gaps = 1/104 (0%)
Frame = +2
Query: 314 SATLTSEDAL-KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA 490
SA TS D L +LY ++ ++R E A +++ I G+ H+Y+GQEAVA G A R+
Sbjct: 19 SAVATSPDRLAELYGKMVLIRAFEDACQRAFRQGKIGGYLHVYTGQEAVATGFLEAFREG 78
Query: 491 DSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
D VIT YR H L+G V++EL G+RTG +GKGGSMHL
Sbjct: 79 DRVITGYRDHAHALLLGCDPKEVMAELFGKRTGLVKGKGGSMHL 122
>UniRef50_Q1EGH8 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=1; Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E1
alpha subunit - Nyctotherus ovalis
Length = 136
Score = 95.1 bits (226), Expect = 1e-18
Identities = 45/128 (35%), Positives = 76/128 (59%), Gaps = 1/128 (0%)
Frame = +2
Query: 218 VVATNAKYSTKKEATFEIKPYKLHKLDQGPA-TSATLTSEDALKLYEQLTILRRIETASG 394
++ ++A++++ E ++ Y++ LD+ T A ++ LK Y + RR+E
Sbjct: 11 IIGSSARFASTVE--IKLPQYEVFNLDKSILPTKAQTNRDEMLKYYHDMNFQRRVEIMCD 68
Query: 395 NLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELT 574
+YK+K +RGFCHL GQEAV+VG+ A + D +ITAYRCHG G + +++E+
Sbjct: 69 EIYKKKEVRGFCHLMDGQEAVSVGVEAGITKEDHLITAYRCHGVLLGRGETAARLIAEMM 128
Query: 575 GRRTGCSR 598
G+ TG S+
Sbjct: 129 GKATGASK 136
>UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Salinibacter
ruber (strain DSM 13855)
Length = 470
Score = 91.9 bits (218), Expect = 1e-17
Identities = 48/119 (40%), Positives = 66/119 (55%), Gaps = 1/119 (0%)
Frame = +2
Query: 266 EIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSG 445
E Y+ + D + ++ L L + + RR E +Y+ + I GF HLY G
Sbjct: 126 ETVTYETYPADTYGHDELGIADDEVLDLLRNMLLQRRFENRCRQMYQRQKISGFLHLYIG 185
Query: 446 QEAVAVG-MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 619
QEAV+ G + A DSVITAYR HG MG++ ++EL G+ TGCS+GKGGSMH
Sbjct: 186 QEAVSTGSVNAIELGDDSVITAYRDHGMGLAMGITPEAGMAELFGKETGCSKGKGGSMH 244
>UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflexi
(class)|Rep: Pyruvate dehydrogenase - Roseiflexus sp.
RS-1
Length = 350
Score = 89.8 bits (213), Expect = 5e-17
Identities = 42/99 (42%), Positives = 58/99 (58%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
L + + Y Q+ ++RR E +Y I GF HLY G+EA AVG AA+R D +
Sbjct: 21 LDAATLIDYYRQMVLIRRFEEKCQEMYTRAKIGGFLHLYIGEEATAVGAIAALRPDDHIF 80
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 619
T YR HG G+ + +++EL G+ TGCS+G GGSMH
Sbjct: 81 THYRDHGHAIARGLDINALMAELFGKVTGCSKGLGGSMH 119
>UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alpha
subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate
dehydrogenase (Lipoamide), alpha subunit - Plesiocystis
pacifica SIR-1
Length = 339
Score = 87.0 bits (206), Expect = 3e-16
Identities = 44/114 (38%), Positives = 61/114 (53%), Gaps = 1/114 (0%)
Frame = +2
Query: 305 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 484
P T + ++ LK + ++ +RR E + Y I GF HLY GQEA+AVG++ AM+
Sbjct: 11 PETLTSAGKDETLKAFREMLRIRRFEETAARAYTRGKISGFLHLYIGQEAIAVGVKLAMQ 70
Query: 485 DADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLV-RTQLLW 643
D V+ YR HG+ G ++EL G+ TG G GGSMH R LW
Sbjct: 71 ANDRVVGTYRDHGYALAQGSDANACMAELFGKATGLVGGVGGSMHYFDRPNGLW 124
>UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|Rep:
Pyruvate dehydrogenase - Acidothermus cellulolyticus
(strain ATCC 43068 / 11B)
Length = 375
Score = 85.4 bits (202), Expect = 1e-15
Identities = 46/115 (40%), Positives = 63/115 (54%), Gaps = 3/115 (2%)
Frame = +2
Query: 305 PATSATLTSEDALKLY-EQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 481
PA D L+ Y + ++RR E + +Y+ I G+CHL G+EA VG+ AM
Sbjct: 29 PADRLAQEPPDKLRAYYRMMQLIRRFEERAAEMYQRAKIGGYCHLNLGEEATVVGLMDAM 88
Query: 482 RDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL--VRTQLL 640
D + T YR HG+ G+ V++EL GR TG S+G GGSMHL T+LL
Sbjct: 89 APHDYLFTTYREHGYALARGIDPGRVMAELFGRTTGVSKGWGGSMHLFDAETRLL 143
>UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidothermus
cellulolyticus 11B|Rep: Pyruvate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 342
Score = 85.0 bits (201), Expect = 1e-15
Identities = 45/114 (39%), Positives = 61/114 (53%)
Frame = +2
Query: 293 LDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMR 472
L + P +A + + L L+E + LR E + +L+ + +++G HL GQEAVA G
Sbjct: 9 LPERPTFTAEVNGRE-LDLFELMVRLRFFERRAHDLFLQGLVKGTSHLSLGQEAVATGFA 67
Query: 473 AAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLVRTQ 634
AAM D YR H T G S+ GV+ EL GR G GKGGSMHL +
Sbjct: 68 AAMEPTDLTFATYRGHAHTLSRGASMTGVMGELMGRSVGLMAGKGGSMHLTSVE 121
>UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=52; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Porphyra
yezoensis
Length = 346
Score = 85.0 bits (201), Expect = 1e-15
Identities = 41/105 (39%), Positives = 59/105 (56%)
Frame = +2
Query: 308 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 487
+T L + L LYE + + R E +Y + + GF HLY+GQEAV+ G+ +
Sbjct: 16 STGLNLNKSNLLVLYEDMLLGRNFEDMCAQMYYKGKMFGFVHLYNGQEAVSTGVIKLLNP 75
Query: 488 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
D V + YR H GV V++EL G+ TGCS+G+GGSMH+
Sbjct: 76 TDYVCSTYRDHVHALSKGVPSKNVMAELFGKETGCSKGRGGSMHI 120
>UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 alpha
subunit; n=1; Toxoplasma gondii|Rep: Apicoplast pyruvate
dehydrogenase E1 alpha subunit - Toxoplasma gondii
Length = 635
Score = 84.6 bits (200), Expect = 2e-15
Identities = 42/92 (45%), Positives = 56/92 (60%)
Frame = +2
Query: 347 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 526
L E + R +E A LY GF HLY+GQEAV+ G+ +R D+V++ YR H
Sbjct: 261 LLEDMLTGRMVEDACARLYYMGKTAGFVHLYTGQEAVSAGVIKLLRPDDAVVSTYRDHVH 320
Query: 527 TYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
GV V V++EL G+ TGCSRG+GGSMH+
Sbjct: 321 ATSKGVPVREVMAELFGKATGCSRGRGGSMHM 352
>UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1
alpha-subunit; n=2; Rhodobacterales|Rep: Tpp-dependent
acetoin dehydrogenase e1 alpha-subunit - Rhodobacterales
bacterium HTCC2654
Length = 335
Score = 83.8 bits (198), Expect = 3e-15
Identities = 44/112 (39%), Positives = 61/112 (54%)
Frame = +2
Query: 287 HKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 466
H + A S T T ED L++Y Q+ +R E + LY + G H+YSG+EAVAVG
Sbjct: 5 HLREDTMAKSKTNT-EDYLRMYRQMVRIRTFEDNANQLYLSAKMPGLTHMYSGEEAVAVG 63
Query: 467 MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+ A+ D D + + +R HG G + EL G+ G RGKGGSMH+
Sbjct: 64 ICEALTDDDRITSTHRGHGHCVAKGAEFKEMFCELLGKEEGYCRGKGGSMHI 115
>UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa sp.
PS|Rep: Pyruvate dehydrogenase - Beggiatoa sp. PS
Length = 331
Score = 81.8 bits (193), Expect = 1e-14
Identities = 38/98 (38%), Positives = 59/98 (60%)
Frame = +2
Query: 332 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 511
E+ L Y L ++RR+E A Y E+ +R HL GQEAVAVG+ ++ +D + +++
Sbjct: 14 EELLTFYRSLLLIRRVEEAIAERYTEQEMRCPTHLCIGQEAVAVGVCKMLQQSDGIFSSH 73
Query: 512 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLV 625
R H G + +++EL G+ TGC G+GGSMHL+
Sbjct: 74 RAHSHYLAKGGDLKAMIAELYGKSTGCCGGRGGSMHLI 111
>UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|Rep:
Pyruvate dehydrogenase - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 332
Score = 80.6 bits (190), Expect = 3e-14
Identities = 40/101 (39%), Positives = 57/101 (56%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
L E + + + +RR E L+K + GF HLY G+EAVAVG +A+R+ D +
Sbjct: 2 LGEEKLVGMLRLMLRIRRFEEKLAELFKRGKLPGFVHLYIGEEAVAVGACSALREDDRIT 61
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLV 625
+ +R HG G V +++EL G+ G RGKGGSMH V
Sbjct: 62 STHRGHGHVIAKGADVSRMMAELLGKEAGYCRGKGGSMHTV 102
>UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Sphingomonas wittichii RW1
Length = 334
Score = 79.8 bits (188), Expect = 5e-14
Identities = 37/108 (34%), Positives = 61/108 (56%)
Frame = +2
Query: 299 QGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAA 478
+G A + + ++LY ++ +R E + G L+ I GF HL GQE V+VG+ A+
Sbjct: 10 RGAAHGRNARAPELIELYRRMVTIREAEKSCGALFAAGEIPGFIHLSDGQEGVSVGVMAS 69
Query: 479 MRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+R D++ + +R HG G+ + G EL G+ G +G+GGSMH+
Sbjct: 70 LRADDTIASTHRGHGHALAKGLGLDGFFRELMGKADGACKGRGGSMHV 117
>UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Antonospora locustae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Antonospora locustae (Nosema locustae)
Length = 342
Score = 79.8 bits (188), Expect = 5e-14
Identities = 39/103 (37%), Positives = 57/103 (55%)
Frame = +2
Query: 314 SATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDAD 493
S + +D KLY ++ +R ++ + +Y +IRGFCHL GQE V + R+ D
Sbjct: 21 SCKIRYDDVEKLYRKMLCMRYMDESISKMYSRGLIRGFCHLDIGQEEVYAALCHVARN-D 79
Query: 494 SVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
I +YRCH + V ++ EL GR G ++GKGGSMHL
Sbjct: 80 KFIGSYRCHALAVAAEIPVREIVGELLGRAGGVAKGKGGSMHL 122
>UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8;
Chlamydiaceae|Rep: Pyruvate Dehydrogenase Alpha -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 342
Score = 79.0 bits (186), Expect = 9e-14
Identities = 35/94 (37%), Positives = 54/94 (57%)
Frame = +2
Query: 341 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 520
+K +Q+ ++R E Y E ++ GF H Y+GQEAVA A V ++YRCH
Sbjct: 32 IKFLKQMVLIREFEARGEEAYLEGLVGGFYHSYAGQEAVATAAIANTGLDPWVFSSYRCH 91
Query: 521 GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
L+ + + + +EL G+ TGC+ G+GGSMH+
Sbjct: 92 ALAILLNIPLQEIAAELLGKETGCALGRGGSMHM 125
>UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=40; Streptococcus|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Streptococcus suis (strain 05ZYH33)
Length = 337
Score = 79.0 bits (186), Expect = 9e-14
Identities = 34/105 (32%), Positives = 60/105 (57%)
Frame = +2
Query: 320 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV 499
++T E L ++ ++ +R ++ L + ++G H G+EA AVG A + D D +
Sbjct: 18 SITKEQHLDMFLKMQQIRDVDMKLNKLVRRGFVQGMTHFSVGEEAAAVGPIAGLTDEDII 77
Query: 500 ITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLVRTQ 634
+ +R HG G+ + G+++EL G+ TG S+G+GGSMHL +
Sbjct: 78 FSHHRGHGHVIAKGIDINGMMAELAGKATGTSKGRGGSMHLANVE 122
>UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E1
component alpha-subunit, putative; n=22; Bacteria|Rep:
Pyruvate dehydrogenase, TPP-dependent E1 component
alpha-subunit, putative - Streptococcus sanguinis
(strain SK36)
Length = 357
Score = 78.2 bits (184), Expect = 2e-13
Identities = 35/100 (35%), Positives = 59/100 (59%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
++ E A +Y+ + +R E + + I GF HLY+G+EA+A G+ A + D D +
Sbjct: 39 VSKEKAKTMYKTMWDIRNFEENTRRFFAAGQIPGFVHLYAGEEAIATGVCANLTDKDYIT 98
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+ +R HG G + G+++E+ G+ TG +GKGGSMH+
Sbjct: 99 STHRGHGHCVAKGGDLKGMMAEIFGKETGLGKGKGGSMHI 138
>UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 339
Score = 77.8 bits (183), Expect = 2e-13
Identities = 45/101 (44%), Positives = 55/101 (54%), Gaps = 5/101 (4%)
Frame = +2
Query: 335 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG---MRAAMRDA--DSV 499
D +L ++ RR E S Y E+ + GF HLYSGQEAVA G M A R D
Sbjct: 5 DRKRLLREMVFFRRFEDRSFEAYMERKVGGFLHLYSGQEAVATGVLEMVQADRGVGFDYA 64
Query: 500 ITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
IT YR H G V++EL G+ TG SRG+GGSMH+
Sbjct: 65 ITGYRDHIHAIKAGAPAREVMAELYGKETGSSRGRGGSMHI 105
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 76.2 bits (179), Expect = 6e-13
Identities = 39/105 (37%), Positives = 57/105 (54%)
Frame = +2
Query: 308 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 487
AT L +D + + +RR ET + L+ + +I+G H GQEA+A G A +
Sbjct: 13 ATPNGLAPKDLRAALKMMLRIRRFETRAKELFLQGVIKGTAHSSVGQEAIAAGACAVLEP 72
Query: 488 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
AD ++T +R HG T G + + +EL GR TG G GGSMH+
Sbjct: 73 ADFILTHHRGHGHTIAKGADLGRMFAELMGRETGYCAGLGGSMHI 117
>UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n=6;
Plasmodium|Rep: Pyruvate dehydrogenase alpha subunit -
Plasmodium falciparum
Length = 608
Score = 76.2 bits (179), Expect = 6e-13
Identities = 39/105 (37%), Positives = 59/105 (56%), Gaps = 1/105 (0%)
Frame = +2
Query: 311 TSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDA 490
+ ++ E+ LYE + + R E LY K + GF HLY+GQEAV+ G+ ++++
Sbjct: 184 SDVNISREEICTLYEDMYLGRLFENLVAKLYYNKRVNGFVHLYNGQEAVSTGIIKNLKNS 243
Query: 491 DSVITAYRCHGWTYLMGVSVLGVLSELTGRRTG-CSRGKGGSMHL 622
D V + YR H GV +L+EL G G ++GKGGSMH+
Sbjct: 244 DFVTSTYRDHVHALSKGVPAHKILNELYGNYYGSTNKGKGGSMHI 288
>UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase
(Lipoamide), E1 component, alpha chain; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Putative pyruvate
dehydrogenase (Lipoamide), E1 component, alpha chain -
Protochlamydia amoebophila (strain UWE25)
Length = 342
Score = 75.8 bits (178), Expect = 8e-13
Identities = 35/100 (35%), Positives = 59/100 (59%)
Frame = +2
Query: 341 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 520
++ ++Q+ +R E + + Y++ I GF H Y GQEA+ A+ ++ T+YRCH
Sbjct: 27 IECFQQMLKIRNFELRAESAYQQGKIGGFFHAYVGQEAIQTAAVQAIGQSNWYATSYRCH 86
Query: 521 GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLVRTQLL 640
L+G + +++EL GR TG ++G+GGSMH +LL
Sbjct: 87 ALALLLGATPNELMAELYGRATGNAKGRGGSMHFFTDRLL 126
>UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; Rhodopseudomonas palustris HaA2|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
Rhodopseudomonas palustris (strain HaA2)
Length = 323
Score = 75.8 bits (178), Expect = 8e-13
Identities = 40/99 (40%), Positives = 56/99 (56%)
Frame = +2
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
SE +L + +R +E Y E+ +R HL GQEAVA AA+ AD ++
Sbjct: 2 SELPRRLLFDMMRIRAVEETIAKRYGEQKMRCPTHLSVGQEAVAAAAGAALEPADLAVSG 61
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLV 625
+R H G S+ +++E+ GR TGCSRGKGGSMHL+
Sbjct: 62 HRAHAHYLAKGGSLKAMIAEIYGRVTGCSRGKGGSMHLI 100
>UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase
alpha-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase alpha-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 326
Score = 75.4 bits (177), Expect = 1e-12
Identities = 40/95 (42%), Positives = 59/95 (62%), Gaps = 1/95 (1%)
Frame = +2
Query: 344 KLYEQLTILRRIETASGNLYK-EKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 520
+L + +R IE ++Y+ E+ +R HL GQEAVAVG+ AA+R D V + +RCH
Sbjct: 5 QLLRTMVRIRCIEEEIADVYRDEQQMRTPVHLSIGQEAVAVGVCAALRTEDVVYSGHRCH 64
Query: 521 GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLV 625
G + +++EL GR TGC+ G+GGS+HLV
Sbjct: 65 AHYLAKGGGLGAMVAELYGRETGCAAGRGGSVHLV 99
>UniRef50_A4X7T3 Cluster: Dehydrogenase, E1 component; n=3;
Actinomycetales|Rep: Dehydrogenase, E1 component -
Salinispora tropica CNB-440
Length = 323
Score = 74.9 bits (176), Expect = 1e-12
Identities = 38/99 (38%), Positives = 56/99 (56%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
+T +++LY + ++RR E + L + I G H Y GQE +A G+ AA+R D V
Sbjct: 1 MTEVGSVRLYRTVRLIRRFEERAIELVRSGHIVGGIHPYVGQEGIAAGVCAALRPDDVVA 60
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 619
+R HG G +++EL GR TG +RG+GGSMH
Sbjct: 61 GTHRGHGHVLAKGADPARMMAELCGRVTGLNRGRGGSMH 99
>UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit
(Lipoamide); n=2; Sulfolobaceae|Rep: Pyruvate
dehydrogenase, alpha subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 345
Score = 74.9 bits (176), Expect = 1e-12
Identities = 43/112 (38%), Positives = 62/112 (55%), Gaps = 9/112 (8%)
Frame = +2
Query: 314 SATLTSEDALKLYEQLTILRRIETASGNLYKEKI---------IRGFCHLYSGQEAVAVG 466
+A L + D L +Y+++ I+R E + +Y E IRG HL GQEAVAVG
Sbjct: 18 NAGLKASDLLNMYKRMLIIRYFEESIRKIYHEGKNPFNMASGRIRGEMHLSIGQEAVAVG 77
Query: 467 MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+RD D V++ +R H GV + G+ +E+ G+ TG +GKGG MHL
Sbjct: 78 TLYDIRDEDVVVSTHRPHHHAIAKGVDLKGLAAEILGKATGLCKGKGGHMHL 129
>UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha
subunit; n=1; Burkholderia xenovorans LB400|Rep:
Putative 2-oxo acid dehydrogenase alpha subunit -
Burkholderia xenovorans (strain LB400)
Length = 334
Score = 74.5 bits (175), Expect = 2e-12
Identities = 32/94 (34%), Positives = 54/94 (57%)
Frame = +2
Query: 341 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 520
+ +Y + ++R +E + L+ + + GF HL GQEAV+ G+ + + D++ T +R H
Sbjct: 20 IDIYRTMVLVREVELSLSRLFADSEVPGFIHLSLGQEAVSAGVASVLEVQDTLATTHRGH 79
Query: 521 GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
G G+ V G E+ GR G +G+GGSMH+
Sbjct: 80 GHVLARGIDVGGFFKEIMGRVGGLCKGRGGSMHV 113
>UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; marine actinobacterium PHSC20C1|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
marine actinobacterium PHSC20C1
Length = 327
Score = 74.5 bits (175), Expect = 2e-12
Identities = 38/96 (39%), Positives = 52/96 (54%)
Frame = +2
Query: 335 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYR 514
DAL+L + +R E L+ + ++RG HL GQEAV VG+ +A+ D++ YR
Sbjct: 17 DALELLRSMYEIRFFEDEIMGLFSQNLVRGSTHLCQGQEAVTVGVCSALSPGDTMTCTYR 76
Query: 515 CHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
HG MG + E+ GR G GKGGSMHL
Sbjct: 77 GHGAVLAMGAPLDRAFGEILGRAGGLCGGKGGSMHL 112
>UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: Dehydrogenase, E1
component - Chloroflexus aurantiacus J-10-fl
Length = 334
Score = 74.1 bits (174), Expect = 3e-12
Identities = 34/94 (36%), Positives = 54/94 (57%)
Frame = +2
Query: 356 QLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYL 535
++ I+R E + L+ ++ G HL GQEAVA+G AAM+ D ++ +R HG
Sbjct: 33 RMQIIRAFEEKAEELFARGLVHGTMHLSIGQEAVAIGASAAMKPGDYLLNHHRGHGHCLA 92
Query: 536 MGVSVLGVLSELTGRRTGCSRGKGGSMHLVRTQL 637
G V +++E G+ TG RG+GGSMH+ ++
Sbjct: 93 WGSDVRLMMAEFLGKETGYCRGRGGSMHIANVEM 126
>UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2;
Bacteria|Rep: Dehydrogenase, E1 component - Comamonas
testosteroni KF-1
Length = 327
Score = 73.7 bits (173), Expect = 3e-12
Identities = 38/94 (40%), Positives = 52/94 (55%)
Frame = +2
Query: 338 ALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC 517
A +L EQ+ +R +E +L K I+G HL GQEA+ G AA + D V + YR
Sbjct: 16 AKELLEQMIRIRLLEEKIADLRKSGEIQGSVHLCIGQEAIYSGSCAARQPGDRVFSTYRG 75
Query: 518 HGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 619
HGW + GV +L+EL R TG G+GGS +
Sbjct: 76 HGWAHACGVPAEAILAELLARETGVCAGRGGSAY 109
>UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 331
Score = 72.1 bits (169), Expect = 1e-11
Identities = 34/98 (34%), Positives = 57/98 (58%)
Frame = +2
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
++ +L+ Y ++ +R+ E + ++ + I G H Y+GQEA VG A+ D D ++
Sbjct: 6 NDRSLEKYRRMQRIRQFEDLAEAIHAQGEIPGSLHTYAGQEASGVGACMALDDTDYMVGT 65
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+R HG G + +++EL G+ TG +GKGGSMHL
Sbjct: 66 HRSHGHPIAKGAKLRPLMAELLGKATGICKGKGGSMHL 103
>UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha; n=58; cellular
organisms|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha - Ralstonia eutropha
(strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 333
Score = 70.5 bits (165), Expect = 3e-11
Identities = 34/100 (34%), Positives = 53/100 (53%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
L E L +Y ++ +R E + I GF HLY+G+EA VG+ + D D +
Sbjct: 14 LDKETLLTVYRKMRTIRDFEERLHVDFGRGDIPGFVHLYAGEEAAGVGILHHLNDGDRIA 73
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+ +R HG GV + ++ E+ G++ G GKGGSMH+
Sbjct: 74 STHRGHGHCIAKGVDPVAMMKEIYGKKGGSCNGKGGSMHI 113
>UniRef50_Q7V0M7 Cluster: Dehydrogenase, E1 component; n=1;
Prochlorococcus marinus subsp. pastoris str.
CCMP1986|Rep: Dehydrogenase, E1 component -
Prochlorococcus marinus subsp. pastoris (strain CCMP
1378 / MED4)
Length = 324
Score = 70.1 bits (164), Expect = 4e-11
Identities = 33/85 (38%), Positives = 53/85 (62%)
Frame = +2
Query: 368 LRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVS 547
+R IE A +L K+ +RG H Y G+EA+A G+ + + D+V + +R HG G +
Sbjct: 41 IRAIEEAIVSLAKDNKLRGPIHSYVGEEAIATGVLSHAKPIDAVTSTHRGHGHYIAKGGN 100
Query: 548 VLGVLSELTGRRTGCSRGKGGSMHL 622
+ ++ EL G+ +GC+ GKGGSMH+
Sbjct: 101 ISMLIDELHGKESGCNGGKGGSMHV 125
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 66.1 bits (154), Expect = 7e-10
Identities = 37/100 (37%), Positives = 50/100 (50%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
L+ ED K Y + + R E Y IRGF HL +GQE++ + A+R D
Sbjct: 132 LSDEDLSKAYYMMQLCRDFENECNQAYMAGKIRGFMHLDNGQESIPALLNDAIRKDDLKH 191
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+ YR H GV V++EL G+ G RG GGSMH+
Sbjct: 192 SYYRDHCHAIACGVDSGAVMAELFGKDGGTCRGTGGSMHV 231
>UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=6; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) alpha chain - Rhizobium loti
(Mesorhizobium loti)
Length = 342
Score = 65.7 bits (153), Expect = 9e-10
Identities = 31/99 (31%), Positives = 54/99 (54%)
Frame = +2
Query: 326 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVIT 505
++E ++ ++ ++RR E + Y +I G HL GQEA A+G+ + + D + +
Sbjct: 23 SAEQLREVLYKMYLIRRFEEGAEESYMRGLIHGTMHLSIGQEASAMGICMPLGEDDQITS 82
Query: 506 AYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+R HG G V + +E G+ TG +G+GGSMH+
Sbjct: 83 THRGHGHCIAKGAEVKRMFAEFFGKTTGYCKGRGGSMHI 121
>UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit; n=2; Clostridium
difficile|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit - Clostridium difficile
(strain 630)
Length = 322
Score = 65.7 bits (153), Expect = 9e-10
Identities = 32/101 (31%), Positives = 55/101 (54%)
Frame = +2
Query: 320 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV 499
+++ E L++Y+++ R+ E + ++ G HL GQEA +V A+ D V
Sbjct: 4 SISKETLLEMYKRMNQARKFEEKVSWFFARGMVHGTTHLSVGQEASSVAAVMALEKGDLV 63
Query: 500 ITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+R H MG+ + +++EL G+ TG +GKGGSMH+
Sbjct: 64 SLTHRGHSQFIGMGIDLNKMMAELMGKETGFCKGKGGSMHI 104
>UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, alpha subunit; n=2; unclassified
Epsilonproteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, E1 component, alpha subunit -
Nitratiruptor sp. (strain SB155-2)
Length = 323
Score = 65.7 bits (153), Expect = 9e-10
Identities = 40/96 (41%), Positives = 51/96 (53%)
Frame = +2
Query: 350 YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWT 529
Y + + R E A+ Y + I GF HL GQEA +VG A D V T YR H
Sbjct: 10 YYLMKLGREFEIAAKQEYMKGNIAGFLHLDIGQEACSVGSMQAF-DKGDVFTHYREHVLA 68
Query: 530 YLMGVSVLGVLSELTGRRTGCSRGKGGSMHLVRTQL 637
G+ V++EL G+ TG S+GKGGSMHL +L
Sbjct: 69 IARGMDPKVVMAELFGKVTGISKGKGGSMHLFDPRL 104
>UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridium
cellulolyticum H10|Rep: Pyruvate dehydrogenase -
Clostridium cellulolyticum H10
Length = 321
Score = 64.5 bits (150), Expect = 2e-09
Identities = 33/101 (32%), Positives = 55/101 (54%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
+ +E ++LY + +R +E YK ++ HL GQEA+A G+ +R D +
Sbjct: 1 MENERFIELYRVMQTIRIVERKIEEEYKNDEMKTPIHLSIGQEAIAAGVCINLRKDDYLF 60
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLV 625
+R H G + +++EL R+TGC+ G+GGSMHL+
Sbjct: 61 GTHRSHAQYIAKGGDIKQMIAELYLRKTGCTSGRGGSMHLM 101
>UniRef50_Q2BFQ9 Cluster: Putative uncharacterized protein; n=1;
Bacillus sp. NRRL B-14911|Rep: Putative uncharacterized
protein - Bacillus sp. NRRL B-14911
Length = 668
Score = 64.1 bits (149), Expect = 3e-09
Identities = 33/100 (33%), Positives = 55/100 (55%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
L+ E +Y+++ +R +E +L+ + + G H GQEA AV A +++ D V
Sbjct: 14 LSQETIDSMYKKMITIRTLEETLLDLFSKGELFGTTHTSIGQEANAVASMAHIKNGDVVF 73
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+ +RCHG G V +++E+ GR TG G+GGS H+
Sbjct: 74 SNHRCHGHYIAYGAPVDQLIAEVMGRVTGVVGGRGGSQHI 113
>UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2;
Alphaproteobacteria|Rep: Dehydrogenase E1 component -
Sinorhizobium medicae WSM419
Length = 342
Score = 63.7 bits (148), Expect = 4e-09
Identities = 35/95 (36%), Positives = 51/95 (53%), Gaps = 1/95 (1%)
Frame = +2
Query: 341 LKLYEQLTILRRIETASGNLYKEKIIRG-FCHLYSGQEAVAVGMRAAMRDADSVITAYRC 517
L+LY + +R E G L+ G HL G+E+ A G+ AAM+ D+ T +R
Sbjct: 10 LELYRTMRRIRTFEERVGELFVRGQSAGSMLHLSIGEESSAAGVCAAMKPQDTFTTHHRG 69
Query: 518 HGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
HG G +++E+ G+ TG RGKGGSMH+
Sbjct: 70 HGIFLARGADPKRMMAEIGGKETGYCRGKGGSMHI 104
>UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2;
Rhodocyclaceae|Rep: Dehydrogenase, E1 component -
Dechloromonas aromatica (strain RCB)
Length = 320
Score = 62.9 bits (146), Expect = 6e-09
Identities = 38/104 (36%), Positives = 55/104 (52%)
Frame = +2
Query: 326 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVIT 505
T+ D L+LYEQL ++R E A + I G C GQEA AVG A+ D ++T
Sbjct: 6 TAVDPLRLYEQLLLIRAYENAIVRGSTDGRIPGTCTSV-GQEAAAVGAINALEADDLILT 64
Query: 506 AYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLVRTQL 637
+R G G +L+E+ GRR G +G+ GS+H+ +L
Sbjct: 65 NHRSAGHLLARGADPGRMLAEVMGRRDGYCKGRSGSLHISAKEL 108
>UniRef50_Q2WB98 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex; n=1; Magnetospirillum magneticum AMB-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 647
Score = 62.5 bits (145), Expect = 8e-09
Identities = 31/87 (35%), Positives = 49/87 (56%)
Frame = +2
Query: 362 TILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMG 541
T++R +E +LY E + G H GQE V + +A+R D +++ +R HG
Sbjct: 17 TLIRVVEERLLSLYGEGRLHGTVHTCIGQEWTGVSVASALRSGDYILSNHRGHGHYLAWT 76
Query: 542 VSVLGVLSELTGRRTGCSRGKGGSMHL 622
V G+++E+ GR +G RG+GGS HL
Sbjct: 77 DDVEGLIAEVMGRESGVCRGRGGSQHL 103
>UniRef50_Q0LRY7 Cluster: Dehydrogenase, E1 component:Transketolase,
central region:Transketolase-like; n=3; cellular
organisms|Rep: Dehydrogenase, E1
component:Transketolase, central
region:Transketolase-like - Caulobacter sp. K31
Length = 680
Score = 62.5 bits (145), Expect = 8e-09
Identities = 37/115 (32%), Positives = 57/115 (49%), Gaps = 8/115 (6%)
Frame = +2
Query: 305 PATSATLTSEDALK------LYEQLTILRRIETASGNLYKEKIIR--GFCHLYSGQEAVA 460
P T+ T EDA K ++ ++ +R E + L + R G HL +GQE V
Sbjct: 2 PGTNPRATKEDAAKAAFLSEMFGKICFVRAFEEEALRLTQANPPRVAGSMHLCAGQEVVP 61
Query: 461 VGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLV 625
V A+ D D V+ YR HGW G+ V++E+ R TG + G+ GS +++
Sbjct: 62 VAAMEALGDEDQVVCTYRGHGWALAAGLDPEAVMAEICQRSTGLNGGRAGSAYMM 116
>UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 320
Score = 62.5 bits (145), Expect = 8e-09
Identities = 33/100 (33%), Positives = 54/100 (54%), Gaps = 1/100 (1%)
Frame = +2
Query: 326 TSEDALKLYEQLTILRRIETASGNLYK-EKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
T E L++ + + RR E L + E + G L +GQEAVA G+ AA+ D ++
Sbjct: 4 TKEKLLEMLRSMLLTRRFEEKLTELCQIEGKVPGMMILCTGQEAVAAGVCAALEPQDVIV 63
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+R HG G +++E G+RTG ++GK G++H+
Sbjct: 64 PNHRSHGHLLARGADPNALMAECFGKRTGFNKGKSGTLHV 103
>UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=2;
Bacteria|Rep: Acetoin dehydrogenase alpha-subunit -
consortium cosmid clone pGZ1
Length = 344
Score = 61.7 bits (143), Expect = 1e-08
Identities = 30/69 (43%), Positives = 43/69 (62%)
Frame = +2
Query: 416 IRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCS 595
+RG HL +GQEAVA G+ + +R D + + +R HG T G + ++ EL GR +G
Sbjct: 52 VRGPLHLSTGQEAVATGVCSQLRADDWLTSTHRGHGHTIAKGADLRRMMHELFGRASGFC 111
Query: 596 RGKGGSMHL 622
GKGGSMH+
Sbjct: 112 GGKGGSMHI 120
>UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
dehydrogenase - Prochlorococcus marinus (strain MIT
9312)
Length = 347
Score = 60.9 bits (141), Expect = 3e-08
Identities = 29/97 (29%), Positives = 52/97 (53%)
Frame = +2
Query: 332 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 511
++ L++ ++ ++R E + ++ G HL GQEA+ VG+ + + D V A+
Sbjct: 26 DELLEMLSKMILIRNAEYKIAKGREFGLVGGPVHLGVGQEAIPVGISQYLNNQDKVFGAH 85
Query: 512 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
R H +G+ + SE+ + +G S+G GGSMHL
Sbjct: 86 RSHSHILSLGIDLKSFFSEILAKSSGISKGMGGSMHL 122
>UniRef50_Q0ET31 Cluster: Dehydrogenase, E1 component; n=1;
Thermoanaerobacter ethanolicus X514|Rep: Dehydrogenase,
E1 component - Thermoanaerobacter ethanolicus X514
Length = 262
Score = 59.7 bits (138), Expect = 6e-08
Identities = 34/110 (30%), Positives = 56/110 (50%), Gaps = 10/110 (9%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKI----------IRGFCHLYSGQEAVAVGMR 472
+ E +++Y ++ +R E Y+E + G HL +GQE VAVG+
Sbjct: 3 IPKETLIRMYLEMVTIRLYEETMAEAYQEGKYPVFNIASGPVPGEMHLAAGQEPVAVGVC 62
Query: 473 AAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
++ D+V+ +R H + GV + + +E+ G+ TG RGKGG MHL
Sbjct: 63 MHLKKEDAVVGTHRPHHFAIAKGVDLKRMTAEIFGKVTGLGRGKGGHMHL 112
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 823
Score = 42.3 bits (95), Expect(2) = 3e-07
Identities = 27/88 (30%), Positives = 39/88 (44%), Gaps = 7/88 (7%)
Frame = +2
Query: 326 TSEDALKLYEQLTILRRIETASGNLYKEKIIRGF-------CHLYSGQEAVAVGMRAAMR 484
+ ED L++Y + I+R ET + G HL GQEA AVG +
Sbjct: 40 SDEDLLRIYRDMLIIREFETMLSLIKTRGEYNGIKYDYPGPAHLSIGQEAAAVGQAFILD 99
Query: 485 DADSVITAYRCHGWTYLMGVSVLGVLSE 568
D + ++R HG G+S + LSE
Sbjct: 100 KNDFIFGSHRSHGEVIAKGLSAIEKLSE 127
Score = 34.7 bits (76), Expect(2) = 3e-07
Identities = 14/23 (60%), Positives = 18/23 (78%)
Frame = +2
Query: 554 GVLSELTGRRTGCSRGKGGSMHL 622
GVL+E+ GR TG +G GGSMH+
Sbjct: 167 GVLAEIFGRETGFQKGLGGSMHV 189
>UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12;
Bacteria|Rep: Pyruvate dehydrogenase - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 344
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/95 (35%), Positives = 50/95 (52%), Gaps = 2/95 (2%)
Frame = +2
Query: 344 KLYEQLTILRRIETASGNLYK--EKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRC 517
+ YE+ ILR G + + +I G HL +GQE VA G+ A + D+V +R
Sbjct: 37 RTYEE-AILREYHADKGPGFDIGKGLIPGEMHLSAGQEPVAAGVCAHLTTDDAVTATHRP 95
Query: 518 HGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
H + GV + + +E+ GR G RG+GG MHL
Sbjct: 96 HHFAVAHGVDLRRMTAEIFGREDGLGRGRGGHMHL 130
>UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=1;
Haloferax volcanii|Rep: 2-oxo acid dehydrogenase subunit
E1 - Halobacterium volcanii (Haloferax volcanii)
Length = 353
Score = 57.2 bits (132), Expect = 3e-07
Identities = 29/69 (42%), Positives = 39/69 (56%)
Frame = +2
Query: 416 IRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCS 595
I G HL +G EA G+ +RD D+V +R H GV + + +E+ GR+TG
Sbjct: 43 IPGELHLAAGHEASGAGVCMHLRDDDTVTAPHRPHHIAIAKGVDLKRMTAEIFGRKTGLC 102
Query: 596 RGKGGSMHL 622
RGKGG MHL
Sbjct: 103 RGKGGHMHL 111
>UniRef50_Q748I3 Cluster: Dehydrogenase, E1 component, alpha and
beta subunits; n=1; Geobacter sulfurreducens|Rep:
Dehydrogenase, E1 component, alpha and beta subunits -
Geobacter sulfurreducens
Length = 652
Score = 56.4 bits (130), Expect = 6e-07
Identities = 29/97 (29%), Positives = 49/97 (50%)
Frame = +2
Query: 332 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 511
+D +L +R++E L+ E ++ G H GQE V + A++ D+V + +
Sbjct: 11 KDCYELTVTALTIRKVEERLLELFSEGVLNGTIHTCIGQEWTGVAVANALQAGDTVFSNH 70
Query: 512 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
R HG + V G+++E+ G+ G G GGS HL
Sbjct: 71 RGHGHYIALTGDVYGLIAEIMGKDDGVCGGVGGSQHL 107
>UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. EAN1pec
Length = 332
Score = 55.6 bits (128), Expect = 1e-06
Identities = 29/95 (30%), Positives = 48/95 (50%)
Frame = +2
Query: 344 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHG 523
+LYE +T+++ + ++ GQEA+A M +R D ++T YR
Sbjct: 16 RLYELMTLMKAADDRLSRGIASGELQCVYWPPRGQEAIAAAMGVCLRSDDQLVTTYRGLH 75
Query: 524 WTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLVR 628
GV ++ + E+ GR+ G RGKGG+MH+ R
Sbjct: 76 DLIGKGVPLVEIYGEMLGRQVGSGRGKGGTMHIAR 110
>UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Probable pyruvate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 344
Score = 55.6 bits (128), Expect = 1e-06
Identities = 32/111 (28%), Positives = 49/111 (44%), Gaps = 3/111 (2%)
Frame = +2
Query: 299 QGPATSATLTSE---DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 469
Q PA AT+T D L Y + + R E G ++ + G+ H G EA
Sbjct: 13 QNPAADATVTERSDADLLSTYRLMVLAREFEEQLGAIFAAGKLGGWFHSCIGHEATGAAA 72
Query: 470 RAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
A MR+ D ++ +R G++ + E+ GR T SRG+ G H+
Sbjct: 73 AALMRETDHLVPYHRSRVSILGKGMTARDLAMEIMGRATAPSRGRAGETHI 123
>UniRef50_Q7N3C2 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 650
Score = 53.6 bits (123), Expect = 4e-06
Identities = 28/88 (31%), Positives = 43/88 (48%)
Frame = +2
Query: 365 ILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGV 544
++R E A LY + G H GQE + ++ D V + +RCHG
Sbjct: 11 LIRETEEALLRLYSTGELHGTVHTCIGQELTGAIVCKFLKKNDWVFSNHRCHGHFLSRTG 70
Query: 545 SVLGVLSELTGRRTGCSRGKGGSMHLVR 628
V G+++E+ G+ TG G+GGS HL +
Sbjct: 71 DVTGLIAEVMGKETGVCGGRGGSQHLCK 98
>UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 340
Score = 52.4 bits (120), Expect = 9e-06
Identities = 31/106 (29%), Positives = 55/106 (51%), Gaps = 1/106 (0%)
Frame = +2
Query: 308 ATSATLTSEDALKLYEQLTILRRIETA-SGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 484
+ + +L +E A K + ++R +E LY++ I G ++ GQEA+ VG
Sbjct: 16 SAAGSLQAELAHKCLYYMLLMREVEDRIERKLYRQGKILGGVYVGRGQEAIPVGSALVAV 75
Query: 485 DADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
D + ++R ++ GVS VL++ GR G +RG+ G+MH+
Sbjct: 76 PEDVMFPSHRDMAVFFIRGVSARRVLAQYMGRLGGLTRGRDGNMHM 121
>UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Dehydrogenase, E1 component - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 315
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/90 (31%), Positives = 44/90 (48%)
Frame = +2
Query: 347 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 526
++ +L + R +ET +E+ G+ H GQEA +G AA+ D V R W
Sbjct: 12 MFHKLAVSRAVETLMLRHTREERFSGWWHPGEGQEAAPIGATAALEADDYVWYQGRGCAW 71
Query: 527 TYLMGVSVLGVLSELTGRRTGCSRGKGGSM 616
G+ L +L +L G+ G + GKGG +
Sbjct: 72 AIGKGMDPLPILGDLLGKTNGATGGKGGGV 101
>UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase alpha subunit
- Coxiella burnetii
Length = 341
Score = 50.8 bits (116), Expect = 3e-05
Identities = 30/92 (32%), Positives = 51/92 (55%)
Frame = +2
Query: 347 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 526
LY+ L I R IE Y + +R HL GQEA+ + + + + D +++ +R H
Sbjct: 11 LYKLLRI-RMIEEEIVLQYPKGKMRCPTHLSIGQEAIPIMVCENLHNTDLMVSTHRAHAH 69
Query: 527 TYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
G ++ +++EL G+ TG + G+GGSM+L
Sbjct: 70 YLAKGGNLKALIAELHGKVTGATAGRGGSMNL 101
>UniRef50_Q9K3H0 Cluster: Putative pyruvate dehydrogenase alpha
subunit; n=2; Bacteria|Rep: Putative pyruvate
dehydrogenase alpha subunit - Streptomyces coelicolor
Length = 323
Score = 49.6 bits (113), Expect = 6e-05
Identities = 28/94 (29%), Positives = 44/94 (46%)
Frame = +2
Query: 359 LTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLM 538
L ++R E A L+ + + G H GQE + V + + + D V + +R HG
Sbjct: 38 LLMIRHFELAVLELFSQGRLHGTTHTCLGQEYIPVALYPLLDEGDYVFSNHRGHGHYLAR 97
Query: 539 GVSVLGVLSELTGRRTGCSRGKGGSMHLVRTQLL 640
G+L+E+ GR G GGS H+ R + L
Sbjct: 98 FHDPHGLLAEIMGRAGAVCHGVGGSQHIYRDRYL 131
>UniRef50_Q1NYL5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Candidatus Sulcia muelleri
str. Hc (Homalodisca coagulata)
Length = 58
Score = 48.8 bits (111), Expect = 1e-04
Identities = 22/54 (40%), Positives = 35/54 (64%)
Frame = +2
Query: 320 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 481
T+ ++ LK Y+ ++ R+ E +LY ++ IRGF HLY+GQEA+ G+ AM
Sbjct: 3 TINNDIYLKWYKDMSFWRKFEDKCRSLYLKQKIRGFLHLYNGQEAIPAGLVHAM 56
>UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 392
Score = 48.4 bits (110), Expect = 1e-04
Identities = 27/85 (31%), Positives = 45/85 (52%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
++ E LYE + ++RRI+T + L ++ + G GQEA +G ++RD D V
Sbjct: 53 VSDEQLGSLYEDMVVIRRIDTEATALQRQGEL-GLWPPLLGQEASQIGSARSLRDDDFVF 111
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTG 577
++YR +G Y GV + +L G
Sbjct: 112 SSYRENGVAYCRGVDLADILKVWRG 136
>UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway
signal; n=2; Proteobacteria|Rep: Twin-arginine
translocation pathway signal - Mesorhizobium sp. (strain
BNC1)
Length = 375
Score = 48.0 bits (109), Expect = 2e-04
Identities = 34/103 (33%), Positives = 52/103 (50%), Gaps = 10/103 (9%)
Frame = +2
Query: 344 KLYEQLTILRRIE----TASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI--- 502
+L + T + RI T + + + RG+ H Y+GQEAVAVG+ +A+R++ V+
Sbjct: 30 QLVDMFTTILRIRWHERTMADKMLTDPNYRGYNHFYAGQEAVAVGVCSALRNSGGVMHAD 89
Query: 503 TAYRCH---GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
AY H G GV + + +E R TG + G MHL
Sbjct: 90 LAYSTHRPTGHAIAKGVDMKLMAAENDFRATGLNGGYAAEMHL 132
>UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit; n=16;
Actinomycetales|Rep: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit - Streptomyces
avermitilis
Length = 406
Score = 47.6 bits (108), Expect = 3e-04
Identities = 30/102 (29%), Positives = 44/102 (43%)
Frame = +2
Query: 317 ATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADS 496
A +T E+ LY + + RR + + +L ++ + G GQEA +G A RD D
Sbjct: 63 ADITPEELRGLYRDMVLSRRFDAEATSLQRQGEL-GLWASMLGQEAAQIGSGRATRDDDY 121
Query: 497 VITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
V YR HG + GV +L G G + HL
Sbjct: 122 VFPTYREHGVAWCRGVDPTNLLGMFRGVNNGGWDPNSNNFHL 163
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 47.2 bits (107), Expect = 3e-04
Identities = 34/117 (29%), Positives = 53/117 (45%), Gaps = 21/117 (17%)
Frame = +2
Query: 335 DALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYR 514
D LK Y Q+ ++RR E + K ++ G H GQEA AVG + ++ D + +R
Sbjct: 30 DLLKWYSQMKLIRRFEEKILDFEKAGLVHGPAHASIGQEAAAVGAMSVLKTDDQINGTHR 89
Query: 515 CH---------------------GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
H +T M +V +++E+ G TG G+GGSMH+
Sbjct: 90 THHQVLTKLINAQTPSDFDILQSDFTDGMHDAVYRLMAEIMGLNTGYCGGRGGSMHM 146
>UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase;
n=4; Cystobacterineae|Rep: 3-methyl-2-oxobutanoate
dehydrogenase - Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 47.2 bits (107), Expect = 3e-04
Identities = 29/106 (27%), Positives = 49/106 (46%)
Frame = +2
Query: 302 GPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAM 481
G TL + L+LY + + R ++ L ++ I GF G+EA +G AAM
Sbjct: 44 GAPDEVTLPDAEVLRLYRLMVLNRSLDERMITLQRQGRI-GFYIGSIGEEATILGSAAAM 102
Query: 482 RDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMH 619
++D + YR HG + G+ ++ L +L G +G+ H
Sbjct: 103 AESDWIFPCYREHGAALMRGMPLVTFLCDLFGNAGDAMKGRQMPCH 148
>UniRef50_A5U0N1 Cluster: Dehydrogenase E1 component; n=7;
Mycobacterium tuberculosis complex|Rep: Dehydrogenase E1
component - Mycobacterium tuberculosis (strain ATCC
25177 / H37Ra)
Length = 334
Score = 46.8 bits (106), Expect = 4e-04
Identities = 28/93 (30%), Positives = 46/93 (49%)
Frame = +2
Query: 344 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHG 523
+LY ++ +LR ++ A L E +I G GQEAV+VG AA+ + D +IT +R H
Sbjct: 18 ELYRRMWVLRLLDMALEQLRIEGLINGPLQGGFGQEAVSVGAAAALGEGDVIITTHRPHA 77
Query: 524 WTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
+ V++++ G G G H+
Sbjct: 78 QHVGTDAPLGPVIADMLGATAGDLEGADEDAHI 110
>UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Propionibacterium acnes|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit -
Propionibacterium acnes
Length = 381
Score = 46.0 bits (104), Expect = 8e-04
Identities = 28/96 (29%), Positives = 43/96 (44%)
Frame = +2
Query: 290 KLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGM 469
+L P L +D +K E + + RR++ + L + + G GQEA G
Sbjct: 40 RLTTHPDFPVDLVDDDLVKALEMMVMTRRLDVEATALQRHGEL-GLWPPLLGQEATQAGA 98
Query: 470 RAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 577
A+R+ D V YR G + MGVS+ +L G
Sbjct: 99 WLALREGDQVFPTYREQGLAHAMGVSLADILGAWDG 134
>UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Bacillus sp. SG-1|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
sp. SG-1
Length = 364
Score = 45.6 bits (103), Expect = 0.001
Identities = 27/95 (28%), Positives = 47/95 (49%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
+T + A + Y + +R + + +L ++ I + + GQEA VG AA+++ D +
Sbjct: 35 ITEQLAKEFYRHMVRIRTFDKKAISLQRQGRIGTYAP-FEGQEASQVGSSAALKEDDWMF 93
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKG 607
+YR HG G S+ +L GR GC +G
Sbjct: 94 PSYRDHGAAMTFGHSLRNILLFWKGRNEGCVPPQG 128
>UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=2; Bacteria|Rep: Pyruvate dehydrogenase E1
component, alpha subunit - Frankia alni (strain ACN14a)
Length = 342
Score = 45.2 bits (102), Expect = 0.001
Identities = 29/94 (30%), Positives = 42/94 (44%)
Frame = +2
Query: 341 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 520
L L+ T + R + +L I G + GQE A + A +R D V+T YR
Sbjct: 25 LGLFRTATRIARFDEKYRSLMTSGAIGGMYYSPRGQEFAAASVAAHLRRDDYVVTTYRGL 84
Query: 521 GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
GV + + +E G+ G GKGG MH+
Sbjct: 85 HDQIAKGVPLRELWAEYLGKAAGTCGGKGGPMHV 118
>UniRef50_UPI0000384B37 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Magnetospirillum
magnetotacticum MS-1|Rep: COG1071:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Magnetospirillum magnetotacticum MS-1
Length = 311
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/92 (31%), Positives = 44/92 (47%)
Frame = +2
Query: 347 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGW 526
L Q+ +R + K K R HL G EA+AV + AAM + DS+ +R +
Sbjct: 12 LARQVLRVRLAQMLINEALKAKKFRVPVHLALGHEAIAVAVGAAMAEGDSLFLTHRNIHY 71
Query: 527 TYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
S+ +SEL R G + G+ GSM++
Sbjct: 72 NIARATSLAAEVSELALRPDGLAGGRLGSMNM 103
>UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Bacilli|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 368
Score = 44.8 bits (101), Expect = 0.002
Identities = 31/95 (32%), Positives = 47/95 (49%), Gaps = 2/95 (2%)
Frame = +2
Query: 329 SEDALK-LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR-DADSVI 502
S D LK +Y ++ LR + NL ++ + F +SGQEA VG +R D D +
Sbjct: 35 SVDQLKDVYRKMVYLRVFDQRCLNLQRQGRMGTFAP-FSGQEASQVGSAYLLRPDRDWIF 93
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKG 607
YR HG ++MGV ++ +L G G +G
Sbjct: 94 PTYRDHGAMHVMGVPLVNILRYFMGDEQGSHAPQG 128
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 44.8 bits (101), Expect = 0.002
Identities = 33/114 (28%), Positives = 49/114 (42%), Gaps = 21/114 (18%)
Frame = +2
Query: 344 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH- 520
++ EQL ++R E L KE ++ G H GQE AVG+ +A+ D + +R H
Sbjct: 47 RMLEQLFLIRHFEERLLELSKEGLLHGPAHASIGQEGAAVGLMSALTSGDKINGTHRMHH 106
Query: 521 --------------------GWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
G+ V SE+ G ++G G+GGSMHL
Sbjct: 107 QFLAKTLNHALVAEYDPLDQGFPQAAQEVVFKTYSEILGLKSGYCGGRGGSMHL 160
>UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3;
Actinomycetales|Rep: Pyruvate dehydrogenase -
Kineococcus radiotolerans SRS30216
Length = 390
Score = 44.4 bits (100), Expect = 0.002
Identities = 29/91 (31%), Positives = 40/91 (43%)
Frame = +2
Query: 305 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 484
P L E+ L L + +LRR++ A G + + G GQEA VG A R
Sbjct: 36 PEHEVDLEPEELLALLRDMVLLRRLD-AEGEALQRQGQLGLWPGSRGQEAAQVGSATACR 94
Query: 485 DADSVITAYRCHGWTYLMGVSVLGVLSELTG 577
D V +YR HG G+ + +LS G
Sbjct: 95 RQDQVFPSYRDHGAVLGRGIDPVDILSIFRG 125
>UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 327
Score = 41.9 bits (94), Expect = 0.013
Identities = 22/60 (36%), Positives = 30/60 (50%)
Frame = +2
Query: 443 GQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
GQE + + ++ D D V T YR G + +E+ GR TG +GKGG MHL
Sbjct: 47 GQEIIPAAISVSLTDDDYVNTIYRGGHDQIAKGFPLPDYWAEIAGRVTGACKGKGGPMHL 106
>UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 325
Score = 41.5 bits (93), Expect = 0.017
Identities = 30/103 (29%), Positives = 44/103 (42%), Gaps = 1/103 (0%)
Frame = +2
Query: 332 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAY 511
E L YE++ E E I GF H GQE VG AA+ D ++ A+
Sbjct: 10 ERLLDFYERMVRCMLWEQKLLRFIDEGKISGFYHAGRGQEGTQVGAVAALGPDDYMMYAH 69
Query: 512 RCHGWTYLMGVSVLGVLSELTGRRTGCSRGKG-GSMHLVRTQL 637
R G+ G+ + + + G +RG G G +H+ QL
Sbjct: 70 RGCGYMVARGMPMSKLFGDFLANTEGSTRGLGAGIVHIAWPQL 112
>UniRef50_Q9HN77 Cluster: Pyruvate dehydrogenase alpha subunit; n=8;
Halobacteriaceae|Rep: Pyruvate dehydrogenase alpha
subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 419
Score = 41.1 bits (92), Expect = 0.022
Identities = 23/89 (25%), Positives = 45/89 (50%)
Frame = +2
Query: 323 LTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVI 502
LT ++ +++Y + + RR + + +L ++ I + L SGQE + A+ D D ++
Sbjct: 79 LTDDELVEMYRYMKLARRFDERAVSLQRQGRIGTYPPL-SGQEGAQIASAMALADDDWIV 137
Query: 503 TAYRCHGWTYLMGVSVLGVLSELTGRRTG 589
+YR HG + + G+ + L G G
Sbjct: 138 PSYREHGASLVRGLPLKDTLLYWMGDERG 166
>UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=5; Proteobacteria|Rep: Pyruvate dehydrogenase
E1 component alpha subunit - Ralstonia solanacearum
UW551
Length = 368
Score = 39.9 bits (89), Expect = 0.051
Identities = 24/70 (34%), Positives = 36/70 (51%)
Frame = +2
Query: 341 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 520
L LY + + R +T + L + + F GQEA+ VG+ +AMR D + +YR H
Sbjct: 36 LALYRAMVLTRAFDTKAIALQRTGKLGTFASSV-GQEAIGVGVASAMRAEDVLFPSYRDH 94
Query: 521 GWTYLMGVSV 550
L GVS+
Sbjct: 95 SAQLLRGVSM 104
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 39.5 bits (88), Expect = 0.068
Identities = 31/112 (27%), Positives = 48/112 (42%), Gaps = 20/112 (17%)
Frame = +2
Query: 347 LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH-- 520
+ Q+ ++R E L + ++ G H GQE AVG +MR +D + ++R H
Sbjct: 34 MLSQMHLIRAFEEKVLELAGQGLVHGPAHSAIGQEGGAVGSAVSMRPSDQINGSHRAHHQ 93
Query: 521 ------GWTYLMGVS------------VLGVLSELTGRRTGCSRGKGGSMHL 622
G+ G+ L+E+ G G RG+GGSMHL
Sbjct: 94 FLAKALGYVAQKGIDPKAAFDQDIRTLAQRTLAEILGLSQGFCRGRGGSMHL 145
>UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 415
Score = 39.5 bits (88), Expect = 0.068
Identities = 31/113 (27%), Positives = 48/113 (42%), Gaps = 3/113 (2%)
Frame = +2
Query: 293 LDQGPATSATLTSEDALKL---YEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAV 463
L + P SA DA KL Y + +RR + + L ++ + + L +GQEA +
Sbjct: 45 LGEDPVFSAYANRLDAEKLRGFYADMAAIRRFDQEATALQRQGQLALWVPL-TGQEAAQI 103
Query: 464 GMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
G A + D + YR HG V + +L + G G K + HL
Sbjct: 104 GSGRASQPQDYIFPTYREHGVALTRNVDLAELLRQFRGVSNGGWNPKDTNFHL 156
>UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha
subunit; n=3; Coxiella burnetii|Rep: Dehydrogenase, E1
component, alpha subunit - Coxiella burnetii
Length = 368
Score = 38.7 bits (86), Expect = 0.12
Identities = 24/83 (28%), Positives = 42/83 (50%)
Frame = +2
Query: 341 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 520
L LY ++ ++R+++ + NL + + G GQEAV +GM +AM+ D YR
Sbjct: 39 LYLYRRMALIRQLDNKAINLQRTGKM-GTYPSSRGQEAVGIGMGSAMQKEDIFCPYYRDQ 97
Query: 521 GWTYLMGVSVLGVLSELTGRRTG 589
G + G+ + +L+ G G
Sbjct: 98 GALFEHGIKLSEILAYWGGDERG 120
>UniRef50_A2C5U8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=1; Prochlorococcus marinus str. MIT
9303|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Prochlorococcus marinus (strain MIT 9303)
Length = 280
Score = 38.7 bits (86), Expect = 0.12
Identities = 23/85 (27%), Positives = 39/85 (45%)
Frame = +2
Query: 368 LRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVS 547
+R + A + Y + +R HL GQE ++ + D +++R H +
Sbjct: 1 MRAFQLAIADEYHNQKMRCPVHLSIGQEYWLPLVKKFFQKTDRCFSSHRSHSMYLALACD 60
Query: 548 VLGVLSELTGRRTGCSRGKGGSMHL 622
+++EL G G +G GGSMHL
Sbjct: 61 PESLIAELHGSAFGSLQGLGGSMHL 85
>UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC
1.2.4.1) E1-alpha chain; n=2; Thermus thermophilus|Rep:
Pyruvate dehydrogenase (Lipoamide) (EC 1.2.4.1) E1-alpha
chain - Thermus thermophilus (strain HB8 / ATCC 27634 /
DSM 579)
Length = 346
Score = 38.3 bits (85), Expect = 0.16
Identities = 25/82 (30%), Positives = 42/82 (51%)
Frame = +2
Query: 269 IKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQ 448
+KP + LD+G L E+AL+LY + R + + L ++ + G + GQ
Sbjct: 1 MKPKVVRYLDEG---EFPLAEEEALRLYRAMRRARFFDEKALTLQRQGRL-GVYAPFMGQ 56
Query: 449 EAVAVGMRAAMRDADSVITAYR 514
EA VG+ A+ + D V+ +YR
Sbjct: 57 EAAQVGVALALEERDWVVPSYR 78
>UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM
2839)
Length = 367
Score = 38.3 bits (85), Expect = 0.16
Identities = 21/70 (30%), Positives = 37/70 (52%)
Frame = +2
Query: 341 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 520
L LY + + R+ + + + + I F GQEA+ VG+ AMR D ++ +YR H
Sbjct: 36 LPLYRAMVLTRQFDLKAIAMQRTGQIGTFASAL-GQEAIGVGVATAMRRDDVLVPSYRDH 94
Query: 521 GWTYLMGVSV 550
++ GV++
Sbjct: 95 AAQFVRGVTM 104
>UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Brevibacterium
linens BL2|Rep: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit - Brevibacterium linens
BL2
Length = 368
Score = 37.5 bits (83), Expect = 0.27
Identities = 27/97 (27%), Positives = 43/97 (44%), Gaps = 1/97 (1%)
Frame = +2
Query: 290 KLDQGPATSATLTSEDALK-LYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVG 466
+L P + S+ AL LY Q+ ++RR E +L ++ + + +GQEA VG
Sbjct: 26 RLTDTPTEGLRIPSDAALTGLYRQMVLVRRFEAQVTHLTRQGRLATYPSA-AGQEAAEVG 84
Query: 467 MRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTG 577
A+ D + YR GV V +L+ G
Sbjct: 85 ATTALAPNDWLFPTYRDSAALLTRGVPVAEILAAFRG 121
>UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent
dehydrogenase, E1 component alpha subunit; n=2;
Candidatus Phytoplasma asteris|Rep: Thiamine
pyrophosphate-dependent dehydrogenase, E1 component
alpha subunit - Onion yellows phytoplasma
Length = 363
Score = 37.1 bits (82), Expect = 0.36
Identities = 27/82 (32%), Positives = 41/82 (50%)
Frame = +2
Query: 305 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 484
P L+ + LK+Y+ + + R+ + A+ Y+ + G L SGQEA VG+ AA+
Sbjct: 26 PELEPKLSKDVLLKMYKTMVLGRQADLAALK-YQRQGRMGNYLLNSGQEASQVGVAAALE 84
Query: 485 DADSVITAYRCHGWTYLMGVSV 550
D V YR G GVS+
Sbjct: 85 PQDWVSPYYRDAGIFLYRGVSL 106
>UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
CcI3|Rep: Pyruvate dehydrogenase - Frankia sp. (strain
CcI3)
Length = 417
Score = 36.3 bits (80), Expect = 0.63
Identities = 23/79 (29%), Positives = 39/79 (49%)
Frame = +2
Query: 341 LKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCH 520
++ Y + + RR++ + L ++ + + L GQEA VG AA R D + +YR H
Sbjct: 76 MEFYTSMVLARRLDEEATALQRQGELVLWIPL-RGQEAAQVGSAAAARPRDYLFPSYREH 134
Query: 521 GWTYLMGVSVLGVLSELTG 577
+ GV + V+ L G
Sbjct: 135 AVAWHRGVPAVEVIRLLRG 153
>UniRef50_A0QB51 Cluster: Dehydrogenase E1 component superfamily
protein; n=2; Mycobacterium avium|Rep: Dehydrogenase E1
component superfamily protein - Mycobacterium avium
(strain 104)
Length = 297
Score = 36.3 bits (80), Expect = 0.63
Identities = 31/96 (32%), Positives = 45/96 (46%), Gaps = 2/96 (2%)
Frame = +2
Query: 332 EDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV--IT 505
+D L+ Y ++ +LR ++ A I + GQEAVAVG AA+R D V T
Sbjct: 7 DDRLEPYRRMWVLRLLDMALDESAVGAAIDDDAPVDFGQEAVAVGAVAALRPGDLVNATT 66
Query: 506 AYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGS 613
H +G+ + ++EL G G G GGS
Sbjct: 67 PRFRHAQQIGLGLPLGPAIAELLGTTRG---GAGGS 99
>UniRef50_UPI00004D6EAE Cluster: Ras and Rab interactor 1 (Ras
interaction/interference protein 1) (Ras inhibitor
JC99).; n=2; Xenopus tropicalis|Rep: Ras and Rab
interactor 1 (Ras interaction/interference protein 1)
(Ras inhibitor JC99). - Xenopus tropicalis
Length = 752
Score = 35.9 bits (79), Expect = 0.84
Identities = 26/95 (27%), Positives = 42/95 (44%)
Frame = +2
Query: 203 KVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIE 382
KV P+ T ++ ++ + P ++ D G ++S TSED K QLT R+I+
Sbjct: 308 KVPVPLTRTQESKEIEQSSSNGLSPVEVQ--DSGSSSSEEGTSEDFGKFSPQLTRRRKIK 365
Query: 383 TASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 487
SG + F L S + V + + RD
Sbjct: 366 KKSGRSSFRAVSGAFLSLLSPERKVLMFIEEMSRD 400
>UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=5; Bacillaceae|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit -
Oceanobacillus iheyensis
Length = 358
Score = 35.9 bits (79), Expect = 0.84
Identities = 25/82 (30%), Positives = 38/82 (46%)
Frame = +2
Query: 344 KLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHG 523
+ Y QL +R + + NL ++ I G + GQE VG A+ + D ++ YR H
Sbjct: 37 QFYRQLICMRAFDQKAINLQRQGRI-GTYPGFEGQEGAQVGSALALDEDDWMLPTYRDHA 95
Query: 524 WTYLMGVSVLGVLSELTGRRTG 589
+ G S +LS GR G
Sbjct: 96 ASITFGKSYT-ILSSWNGRVEG 116
>UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Tropheryma whipplei|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 370
Score = 35.5 bits (78), Expect = 1.1
Identities = 20/86 (23%), Positives = 41/86 (47%)
Frame = +2
Query: 320 TLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSV 499
+L ED + Y + ++R+I+ + L + + + +Y GQEA +G A + D +
Sbjct: 33 SLDVEDIQRFYRDIILVRQIDHEAALLQRRGELALWPPVY-GQEASQIGATYACSENDMI 91
Query: 500 ITAYRCHGWTYLMGVSVLGVLSELTG 577
+YR H + G+ ++ + G
Sbjct: 92 FPSYRDHAVMHARGIDLVHIAKLFRG 117
>UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Pyruvate dehydrogenase -
Halorubrum lacusprofundi ATCC 49239
Length = 382
Score = 35.5 bits (78), Expect = 1.1
Identities = 23/72 (31%), Positives = 34/72 (47%)
Frame = +2
Query: 308 ATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRD 487
AT L+ E +Y L RR + + +L ++ I + +GQE AVG A+ D
Sbjct: 35 ATVPDLSDERFRAIYRDLVTTRRFDERAVSLQRQGRIGTYAPC-AGQEGSAVGSTHALAD 93
Query: 488 ADSVITAYRCHG 523
D + YR HG
Sbjct: 94 RDLISYQYREHG 105
>UniRef50_A3DC57 Cluster: Methyl-accepting chemotaxis sensory
transducer; n=1; Clostridium thermocellum ATCC
27405|Rep: Methyl-accepting chemotaxis sensory
transducer - Clostridium thermocellum (strain ATCC 27405
/ DSM 1237)
Length = 600
Score = 34.3 bits (75), Expect = 2.6
Identities = 25/102 (24%), Positives = 40/102 (39%), Gaps = 3/102 (2%)
Frame = +2
Query: 191 NTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTIL 370
NT+ V APV+ E +K +K D +A + D L Y +
Sbjct: 198 NTLDAVNAPVLEIQEVLKKVSEGHLNVKVKGDYKGDYAELKNALNNTIDTLHSYIEEISR 257
Query: 371 RRIETASGNL---YKEKIIRGFCHLYSGQEAVAVGMRAAMRD 487
E A GNL EK + F H++ + + V + +R+
Sbjct: 258 VLTEMAKGNLDVSLSEKYLGDFAHIHEALDTIIVSLNGMIRE 299
>UniRef50_A2FVJ6 Cluster: DnaK protein; n=1; Trichomonas vaginalis
G3|Rep: DnaK protein - Trichomonas vaginalis G3
Length = 726
Score = 33.9 bits (74), Expect = 3.4
Identities = 23/63 (36%), Positives = 34/63 (53%)
Frame = +2
Query: 143 DKMSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSAT 322
D K + +A K LAG +TK+ A + +Y+ K TF KP + +D G A+S T
Sbjct: 161 DSQKKKVSAAIK-LAGLKLTKIIDEKTALSLQYAIDKHDTFVSKPKYVAIIDFG-ASSLT 218
Query: 323 LTS 331
L+S
Sbjct: 219 LSS 221
>UniRef50_UPI0000F2D933 Cluster: PREDICTED: similar to doublecortin
domain containing 5; n=1; Monodelphis domestica|Rep:
PREDICTED: similar to doublecortin domain containing 5 -
Monodelphis domestica
Length = 745
Score = 33.5 bits (73), Expect = 4.5
Identities = 27/103 (26%), Positives = 51/103 (49%), Gaps = 3/103 (2%)
Frame = +2
Query: 101 KDH*IN-LGFIEIIIDKMSKLIP--SAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEI 271
KD IN +G+ + + +K++ + AK L G K P + +K++ F +
Sbjct: 240 KDEEINQVGYYFRLPGRKTKIMVCLACAKSLIGQKEVKKLPPTSKFLCAFGSKEQKQFSL 299
Query: 272 KPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNL 400
K + ++QG AT +EDA++ YE L + + +T++ L
Sbjct: 300 KYLNVIGMNQGDL--ATYEAEDAIRHYEDLLLAFQKKTSTHTL 340
>UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Pyruvate dehydrogenase - Frankia sp.
EAN1pec
Length = 358
Score = 33.5 bits (73), Expect = 4.5
Identities = 24/91 (26%), Positives = 39/91 (42%)
Frame = +2
Query: 305 PATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMR 484
P + S Y ++ RR++ + L ++ + + L GQEA VG AA
Sbjct: 31 PRFTVRADSRQTESFYREMVRARRLDEEATALQRQGELVLWIPL-RGQEAAQVGSAAAAE 89
Query: 485 DADSVITAYRCHGWTYLMGVSVLGVLSELTG 577
AD + +YR H + G+ + L L G
Sbjct: 90 PADFLFPSYREHAVVWHRGIPPVEALRLLRG 120
>UniRef50_A7S2A1 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella vectensis
Length = 1324
Score = 33.5 bits (73), Expect = 4.5
Identities = 24/83 (28%), Positives = 38/83 (45%), Gaps = 1/83 (1%)
Frame = -3
Query: 597 REQPVLRPVSSESTPSTLTPMR*VHP*QR-YAVITESASRIAALIPTATASCPEYR*QKP 421
+EQ + R +S + + + PMR HP Q Y TE S A P S +YR Q+P
Sbjct: 895 KEQEICRGLSHCISIADIQPMRQTHPRQNPYMYTTELTSSFAKDSPNVRDSLVQYR-QQP 953
Query: 420 RMIFSLYRFPDAVSILRNIVSCS 352
+ PD + + ++C+
Sbjct: 954 QQRTRPASLPDQSELSKQGLACT 976
>UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit, putative; n=2;
Filobasidiella neoformans|Rep: Branched-chain alpha-keto
acid dehydrogenase E1-alpha subunit, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 504
Score = 33.5 bits (73), Expect = 4.5
Identities = 23/85 (27%), Positives = 38/85 (44%)
Frame = +2
Query: 260 TFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLY 439
TF + + H + G + AT E L +Y +T++ ++ ++ I F
Sbjct: 111 TFRVLDEEGHMVKDGHESQAT--KEQTLSIYRTMTLIPIVDNVLYQSQRQGRI-SFYMQC 167
Query: 440 SGQEAVAVGMRAAMRDADSVITAYR 514
+G+EA VG AAM D + YR
Sbjct: 168 AGEEAAIVGSAAAMLANDEIFGQYR 192
>UniRef50_A1D894 Cluster: Mating-type protein, putative; n=1;
Neosartorya fischeri NRRL 181|Rep: Mating-type protein,
putative - Neosartorya fischeri (strain ATCC 1020 / DSM
3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC
1020 / DSM 3700 / NRRL 181))
Length = 243
Score = 33.5 bits (73), Expect = 4.5
Identities = 16/28 (57%), Positives = 17/28 (60%)
Frame = -3
Query: 627 RTKCMEPPLPREQPVLRPVSSESTPSTL 544
R C+ P L RE VL PVSS TPS L
Sbjct: 113 RNLCLSPSLLRESVVLHPVSSPRTPSPL 140
>UniRef50_Q9Y149 Cluster: Mediator of RNA polymerase II
transcription subunit 15; n=1; Drosophila
melanogaster|Rep: Mediator of RNA polymerase II
transcription subunit 15 - Drosophila melanogaster
(Fruit fly)
Length = 749
Score = 33.1 bits (72), Expect = 5.9
Identities = 14/36 (38%), Positives = 21/36 (58%)
Frame = -2
Query: 613 GTSLAPGATGPAPRQLREHPQHTNAHEISPSVTTIR 506
G + APGA GP P Q++ P + NA + P + I+
Sbjct: 235 GPNAAPGAGGPGPNQMQGGPMNVNAMQQMPPMQQIQ 270
>UniRef50_Q6QXE3 Cluster: ORF24; n=1; Agrotis segetum
granulovirus|Rep: ORF24 - Agrotis segetum granulosis
virus (AsGV) (Agrotis segetumgranulovirus)
Length = 362
Score = 32.7 bits (71), Expect = 7.8
Identities = 23/77 (29%), Positives = 41/77 (53%), Gaps = 2/77 (2%)
Frame = +2
Query: 233 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDAL--KLYEQLTILRRIETASGNLYK 406
+K K F I+ +++LD+ A A LT L + EQ+T +RRI+ N+
Sbjct: 169 SKKPNKAPVRFYIEDL-INRLDEIIAEPAMLTENIRLIKEKVEQMTTIRRIQ----NIAP 223
Query: 407 EKIIRGFCHLYSGQEAV 457
+K ++ + H+Y G+E +
Sbjct: 224 KKELKSYVHIYVGREVI 240
>UniRef50_Q23HD3 Cluster: Cyclic nucleotide-binding domain containing
protein; n=1; Tetrahymena thermophila SB210|Rep: Cyclic
nucleotide-binding domain containing protein -
Tetrahymena thermophila SB210
Length = 1382
Score = 32.7 bits (71), Expect = 7.8
Identities = 24/79 (30%), Positives = 34/79 (43%), Gaps = 4/79 (5%)
Frame = +3
Query: 228 QTQNTARKKRRHSKSSPTNSI-NWIRALQHQPHSLLKMLLSCMNN*RYCGGLKPHQET-- 398
Q NT +S S+ N+I N I+ LQH + N YC KP+Q+
Sbjct: 860 QRNNTLSPNFSYSPSNNNNNITNKIQQLQHSNSNDSNQSHKSKGNSNYCSLFKPYQQNQA 919
Query: 399 -YIKKRSSVVSVTCIQDKK 452
YI S V ++ I+ K
Sbjct: 920 RYISSTFSQVDISNIESNK 938
>UniRef50_A2DM79 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 1353
Score = 32.7 bits (71), Expect = 7.8
Identities = 19/57 (33%), Positives = 28/57 (49%)
Frame = +2
Query: 236 KYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYK 406
+Y+T+K A+F ++ +L KLDQ PA E Y QL L + N Y+
Sbjct: 129 EYNTRKSASFPVRSEELKKLDQPPAIETEFPYEIE---YFQLHYLPAVNILLSNFYE 182
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 626,802,724
Number of Sequences: 1657284
Number of extensions: 11927063
Number of successful extensions: 36626
Number of sequences better than 10.0: 122
Number of HSP's better than 10.0 without gapping: 35162
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 36589
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 48541014171
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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