Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12m01f
(644 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for ... 157 4e-38
X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for ... 157 4e-38
M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase E1... 157 4e-38
M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate ... 157 4e-38
L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase E1... 157 4e-38
J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase al... 157 4e-38
J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein. 157 4e-38
D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase al... 157 4e-38
BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase ... 157 4e-38
AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase ... 157 4e-38
AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase ... 157 4e-38
AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase ... 157 4e-38
AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase ... 157 4e-38
EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1 pro... 152 9e-37
AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase ... 152 9e-37
AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase ... 147 3e-35
M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase co... 144 2e-34
BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase ... 144 2e-34
BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase ... 144 2e-34
BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase ... 144 2e-34
BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase ... 144 2e-34
BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein. 144 2e-34
BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase ... 144 2e-34
BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase ... 143 5e-34
L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase E1... 93 1e-18
AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase ... 77 7e-14
EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein. 43 8e-04
AK125152-1|BAC86065.1| 202|Homo sapiens protein ( Homo sapiens ... 30 8.1
>X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for
liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit.
).
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for
brain pyruvate dehydrogenase (EC 1.2.4.1). ).
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate
dehydrogenase alpha subunit mRNA, complete cds. ).
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein.
Length = 414
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 25 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 81
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 82 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 141
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 142 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 179
>D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 180
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 157 bits (380), Expect = 4e-38
Identities = 73/158 (46%), Positives = 106/158 (67%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 508
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 509 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 155
>EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1
protein.
Length = 428
Score = 152 bits (369), Expect = 9e-37
Identities = 67/123 (54%), Positives = 89/123 (72%)
Frame = +2
Query: 254 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 433
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 434 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGS 613
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGS
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGS 190
Query: 614 MHL 622
MH+
Sbjct: 191 MHM 193
>AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 205
Score = 152 bits (369), Expect = 9e-37
Identities = 67/123 (54%), Positives = 89/123 (72%)
Frame = +2
Query: 254 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 433
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 434 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGS 613
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGS
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGS 190
Query: 614 MHL 622
MH+
Sbjct: 191 MHM 193
>AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 204
Score = 147 bits (357), Expect = 3e-35
Identities = 73/165 (44%), Positives = 106/165 (64%), Gaps = 7/165 (4%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSG-------QEAVAVGMRAAMRD 487
ED LK Y + +RR+E + LYK+KIIRGFCHL G QEA VG+ A +
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQFLLPLTQEACCVGLEAGINP 117
Query: 488 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHL 622
D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 118 TDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHM 162
>M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase
complex protein.
Length = 388
Score = 144 bits (349), Expect = 2e-34
Identities = 65/130 (50%), Positives = 88/130 (67%)
Frame = +2
Query: 233 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 412
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 413 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 592
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 593 SRGKGGSMHL 622
++GKGGSMH+
Sbjct: 144 AKGKGGSMHM 153
>BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 144 bits (349), Expect = 2e-34
Identities = 65/130 (50%), Positives = 88/130 (67%)
Frame = +2
Query: 233 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 412
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 413 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 592
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 593 SRGKGGSMHL 622
++GKGGSMH+
Sbjct: 144 AKGKGGSMHM 153
>BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 144 bits (349), Expect = 2e-34
Identities = 65/130 (50%), Positives = 88/130 (67%)
Frame = +2
Query: 233 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 412
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 413 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 592
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 593 SRGKGGSMHL 622
++GKGGSMH+
Sbjct: 144 AKGKGGSMHM 153
>BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 144 bits (349), Expect = 2e-34
Identities = 65/130 (50%), Positives = 88/130 (67%)
Frame = +2
Query: 233 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 412
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 413 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 592
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 593 SRGKGGSMHL 622
++GKGGSMH+
Sbjct: 144 AKGKGGSMHM 153
>BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 144 bits (349), Expect = 2e-34
Identities = 65/130 (50%), Positives = 88/130 (67%)
Frame = +2
Query: 233 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 412
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 413 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 592
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 593 SRGKGGSMHL 622
++GKGGSMH+
Sbjct: 144 AKGKGGSMHM 153
>BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein.
Length = 407
Score = 144 bits (349), Expect = 2e-34
Identities = 65/130 (50%), Positives = 88/130 (67%)
Frame = +2
Query: 233 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 412
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 43 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 102
Query: 413 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 592
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 103 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 162
Query: 593 SRGKGGSMHL 622
++GKGGSMH+
Sbjct: 163 AKGKGGSMHM 172
>BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 144 bits (349), Expect = 2e-34
Identities = 65/130 (50%), Positives = 88/130 (67%)
Frame = +2
Query: 233 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 412
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 413 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 592
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 593 SRGKGGSMHL 622
++GKGGSMH+
Sbjct: 144 AKGKGGSMHM 153
>BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 143 bits (346), Expect = 5e-34
Identities = 65/130 (50%), Positives = 87/130 (66%)
Frame = +2
Query: 233 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 412
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 413 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 592
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGPSVRSILAELTGRRGGC 143
Query: 593 SRGKGGSMHL 622
++GKGGSMH+
Sbjct: 144 AKGKGGSMHM 153
>L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit precursor protein.
Length = 390
Score = 92.7 bits (220), Expect = 1e-18
Identities = 46/110 (41%), Positives = 67/110 (60%)
Frame = +2
Query: 149 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 328
M K++ + + L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSPVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 329 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAA 478
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLERA 107
>AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 121
Score = 76.6 bits (180), Expect = 7e-14
Identities = 33/61 (54%), Positives = 43/61 (70%)
Frame = +2
Query: 254 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 433
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 61 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 120
Query: 434 L 436
L
Sbjct: 121 L 121
>EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein.
Length = 261
Score = 43.2 bits (97), Expect = 8e-04
Identities = 17/26 (65%), Positives = 23/26 (88%)
Frame = +2
Query: 545 SVLGVLSELTGRRTGCSRGKGGSMHL 622
SV +L+ELTGR+ GC++GKGGSMH+
Sbjct: 1 SVREILAELTGRKGGCAKGKGGSMHM 26
>AK125152-1|BAC86065.1| 202|Homo sapiens protein ( Homo sapiens
cDNA FLJ43162 fis, clone FCBBF2007510. ).
Length = 202
Score = 29.9 bits (64), Expect = 8.1
Identities = 19/50 (38%), Positives = 25/50 (50%), Gaps = 4/50 (8%)
Frame = +3
Query: 486 MQTQ*SPRIVVTDGLISWAL----VCWGCSRS*RGAGPVAPGAREVPCIW 623
M ++ R+V+T +S AL CWGC+ S AGP AR C W
Sbjct: 1 MHSEPGARLVLTLQTLSRALSNLKACWGCNVSFTHAGPFQKSARS--CNW 48
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,206,207
Number of Sequences: 237096
Number of extensions: 1846457
Number of successful extensions: 5334
Number of sequences better than 10.0: 28
Number of HSP's better than 10.0 without gapping: 5080
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5305
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7141427170
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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