Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12k06f
(605 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC039152-1|AAH39152.1| 277|Homo sapiens HES1 protein protein. 91 3e-18
L19314-1|AAA65220.1| 280|Homo sapiens HRY protein. 88 2e-17
CR541843-1|CAG46641.1| 280|Homo sapiens HES1 protein. 88 2e-17
AK000415-1|BAA91149.1| 280|Homo sapiens protein ( Homo sapiens ... 88 2e-17
AF264785-1|AAF73060.1| 280|Homo sapiens hairy protein. 88 2e-17
BC012351-1|AAH12351.1| 221|Homo sapiens hairy and enhancer of s... 81 3e-15
AL645608-10|CAI15572.1| 221|Homo sapiens hairy and enhancer of ... 81 3e-15
AB048791-1|BAB13510.1| 221|Homo sapiens bHLH factor Hes4 protein. 81 3e-15
BC142687-1|AAI42688.1| 173|Homo sapiens HES2 protein protein. 75 3e-13
BC132698-1|AAI32699.1| 173|Homo sapiens hairy and enhancer of s... 75 3e-13
AL031848-4|CAB46198.1| 173|Homo sapiens hairy and enhancer of s... 75 3e-13
BC007939-1|AAH07939.1| 224|Homo sapiens hairy and enhancer of s... 61 3e-09
AC016757-5|AAY24337.1| 224|Homo sapiens unknown protein. 61 3e-09
AB035179-1|BAA96082.1| 224|Homo sapiens HES6 protein. 61 3e-09
AF260237-1|AAK51634.1| 222|Homo sapiens hairy/enhancer of split... 59 1e-08
BT020068-1|AAV38871.1| 337|Homo sapiens hairy/enhancer-of-split... 58 2e-08
BT020067-1|AAV38870.1| 337|Homo sapiens hairy/enhancer-of-split... 58 2e-08
BC007707-1|AAH07707.1| 337|Homo sapiens hairy/enhancer-of-split... 58 2e-08
AL078594-2|CAI20068.1| 291|Homo sapiens hairy/enhancer-of-split... 58 2e-08
AL078594-1|CAB87581.1| 337|Homo sapiens hairy/enhancer-of-split... 58 2e-08
AJ249545-1|CAB56839.1| 337|Homo sapiens basic-helix-loop-helix ... 58 2e-08
AF311884-1|AAG31157.1| 337|Homo sapiens hairy-related transcrip... 58 2e-08
AF237949-1|AAF44781.1| 337|Homo sapiens GRIDLOCK protein. 58 2e-08
AF232238-1|AAF37296.1| 337|Homo sapiens HES-related repressor p... 58 2e-08
AF173901-1|AAF20173.1| 337|Homo sapiens basic helix-loop-helix ... 58 2e-08
AB044755-1|BAA96781.1| 337|Homo sapiens basic-helix-loop-helix ... 58 2e-08
BT020065-1|AAV38868.1| 304|Homo sapiens hairy/enhancer-of-split... 57 4e-08
BC001873-1|AAH01873.1| 304|Homo sapiens hairy/enhancer-of-split... 57 4e-08
AJ272214-1|CAB75715.1| 304|Homo sapiens HEY1 protein protein. 57 4e-08
AF311883-1|AAG31156.1| 304|Homo sapiens hairy-related transcrip... 57 4e-08
AF254637-1|AAL06278.1| 304|Homo sapiens basic helix-loop-helix ... 57 4e-08
AF232239-1|AAF37297.1| 304|Homo sapiens HES-related repressor p... 57 4e-08
AF176422-1|AAD51749.1| 304|Homo sapiens cardiovascular helix-lo... 57 4e-08
AF151522-1|AAD38967.1| 304|Homo sapiens hairy and enhancer of s... 57 4e-08
BC006087-1|AAH06087.1| 328|Homo sapiens hairy/enhancer-of-split... 55 2e-07
AJ272215-1|CAB75716.1| 328|Homo sapiens HEYL protein protein. 55 2e-07
AF311885-1|AAG31158.1| 328|Homo sapiens hairy-related transcrip... 55 2e-07
AL035404-1|CAI19572.1| 328|Homo sapiens hairy/enhancer-of-split... 55 2e-07
AK092437-1|BAC03890.1| 308|Homo sapiens protein ( Homo sapiens ... 54 4e-07
AK075040-1|BAC11368.1| 214|Homo sapiens protein ( Homo sapiens ... 51 4e-06
AB049064-1|BAB39525.1| 225|Homo sapiens bHLH factor Hes7 protein. 51 4e-06
DQ272660-1|ABB83829.1| 166|Homo sapiens HES5 protein. 43 7e-04
AL031847-3|CAI19439.1| 180|Homo sapiens hairy and enhancer of s... 42 0.002
BC012091-1|AAH12091.1| 76|Homo sapiens HES2 protein protein. 41 0.003
AL031848-5|CAB46199.1| 76|Homo sapiens hairy and enhancer of s... 41 0.003
EF015896-1|ABM64207.1| 482|Homo sapiens basic helix-loop-helix ... 40 0.005
EF015895-1|ABM64206.1| 412|Homo sapiens basic helix-loop-helix ... 40 0.005
CR456921-1|CAG33202.1| 412|Homo sapiens BHLHB2 protein. 40 0.005
BC082238-1|AAH82238.1| 412|Homo sapiens basic helix-loop-helix ... 40 0.005
BC025968-1|AAH25968.1| 482|Homo sapiens basic helix-loop-helix ... 40 0.005
AY665467-1|AAV54602.1| 482|Homo sapiens basic helix-loop-helix ... 40 0.005
AF353635-1|AAK49525.1| 409|Homo sapiens bHLH transcription fact... 40 0.005
AB044088-1|BAB21502.1| 482|Homo sapiens bHLH protein DEC2 protein. 40 0.005
AB043885-1|BAB18565.1| 412|Homo sapiens bHLH transcriptional fa... 40 0.005
AB004066-1|BAA21720.1| 412|Homo sapiens DEC1 protein. 40 0.005
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 35 0.19
AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal ... 35 0.19
AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal... 35 0.19
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 35 0.19
AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal ... 35 0.19
AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein. 35 0.19
AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein. 35 0.19
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 35 0.19
BC087840-1|AAH87840.1| 172|Homo sapiens HES5 protein protein. 34 0.34
BC032586-1|AAH32586.1| 363|Homo sapiens MXD3 protein protein. 30 7.3
BC000745-1|AAH00745.1| 206|Homo sapiens MAX dimerization protei... 30 7.3
AK222579-1|BAD96299.1| 206|Homo sapiens MAX dimerization protei... 30 7.3
AK057034-1|BAB71352.1| 193|Homo sapiens protein ( Homo sapiens ... 30 7.3
AF114834-1|AAP97233.1| 206|Homo sapiens Myx protein. 30 7.3
D26361-1|BAA05392.2| 1652|Homo sapiens KIAA0042 protein. 29 9.6
BC113742-1|AAI13743.1| 1648|Homo sapiens kinesin family member 1... 29 9.6
AL445483-1|CAI17049.1| 1648|Homo sapiens kinesin family member 1... 29 9.6
>BC039152-1|AAH39152.1| 277|Homo sapiens HES1 protein protein.
Length = 277
Score = 91.1 bits (216), Expect = 3e-18
Identities = 51/141 (36%), Positives = 85/141 (60%), Gaps = 3/141 (2%)
Frame = +3
Query: 60 NMSYEIAYSVAEDGPQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGE 239
N S +A SV +P + + ++RK KP++E++RRARIN L +LK L++ AL+ +
Sbjct: 9 NSSSPVAASVNTTPDKPKTAS-EHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSS 67
Query: 240 NVAKLEKADILELTV---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIP 410
+KLEKADILE+TV +P+V + ++RAGF+ NEV+R L++
Sbjct: 68 RHSKLEKADILEMTVKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCE 126
Query: 411 GVDVRLGTQLMTHLGHRLNEM 473
GV+ + T+L+ HL + + ++
Sbjct: 127 GVNTEVRTRLLGHLANCMTQI 147
>L19314-1|AAA65220.1| 280|Homo sapiens HRY protein.
Length = 280
Score = 88.2 bits (209), Expect = 2e-17
Identities = 46/127 (36%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 102 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 281
P ++RK KP++E++RRARIN L +LK L++ AL+ + +KLEKADILE+T
Sbjct: 25 PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84
Query: 282 V---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 452
V +P+V + ++RAGF+ NEV+R L++ GV+ + T+L+ HL
Sbjct: 85 VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 143
Query: 453 GHRLNEM 473
+ + ++
Sbjct: 144 ANCMTQI 150
>CR541843-1|CAG46641.1| 280|Homo sapiens HES1 protein.
Length = 280
Score = 88.2 bits (209), Expect = 2e-17
Identities = 46/127 (36%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 102 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 281
P ++RK KP++E++RRARIN L +LK L++ AL+ + +KLEKADILE+T
Sbjct: 25 PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84
Query: 282 V---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 452
V +P+V + ++RAGF+ NEV+R L++ GV+ + T+L+ HL
Sbjct: 85 VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 143
Query: 453 GHRLNEM 473
+ + ++
Sbjct: 144 ANCMTQI 150
>AK000415-1|BAA91149.1| 280|Homo sapiens protein ( Homo sapiens
cDNA FLJ20408 fis, clone KAT01678. ).
Length = 280
Score = 88.2 bits (209), Expect = 2e-17
Identities = 46/127 (36%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 102 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 281
P ++RK KP++E++RRARIN L +LK L++ AL+ + +KLEKADILE+T
Sbjct: 25 PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84
Query: 282 V---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 452
V +P+V + ++RAGF+ NEV+R L++ GV+ + T+L+ HL
Sbjct: 85 VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 143
Query: 453 GHRLNEM 473
+ + ++
Sbjct: 144 ANCMTQI 150
>AF264785-1|AAF73060.1| 280|Homo sapiens hairy protein.
Length = 280
Score = 88.2 bits (209), Expect = 2e-17
Identities = 46/127 (36%), Positives = 76/127 (59%), Gaps = 3/127 (2%)
Frame = +3
Query: 102 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 281
P ++RK KP++E++RRARIN L +LK L++ AL+ + +KLEKADILE+T
Sbjct: 25 PDKPKTASEHRKSSKPIMEKRRRARINESLSQLKTLILDALKKDSSRHSKLEKADILEMT 84
Query: 282 V---XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 452
V +P+V + ++RAGF+ NEV+R L++ GV+ + T+L+ HL
Sbjct: 85 VKHLRNLQRAQMTAALSTDPSV-LGKYRAGFSECMNEVTRFLSTCEGVNTEVRTRLLGHL 143
Query: 453 GHRLNEM 473
+ + ++
Sbjct: 144 ANCMTQI 150
>BC012351-1|AAH12351.1| 221|Homo sapiens hairy and enhancer of
split 4 (Drosophila) protein.
Length = 221
Score = 81.0 bits (191), Expect = 3e-15
Identities = 46/119 (38%), Positives = 69/119 (57%), Gaps = 3/119 (2%)
Frame = +3
Query: 126 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXX 296
++RK KP++E++RRARIN L +LK L++ AL+ E +KLEKADILE+TV
Sbjct: 33 EHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLR 92
Query: 297 XXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLNEM 473
+P V + ++RAGF EV+R LA GV + ++L+ HL L ++
Sbjct: 93 RVQVTAALSADPAV-LGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQL 150
>AL645608-10|CAI15572.1| 221|Homo sapiens hairy and enhancer of
split 4 (Drosophila) protein.
Length = 221
Score = 81.0 bits (191), Expect = 3e-15
Identities = 46/119 (38%), Positives = 69/119 (57%), Gaps = 3/119 (2%)
Frame = +3
Query: 126 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXX 296
++RK KP++E++RRARIN L +LK L++ AL+ E +KLEKADILE+TV
Sbjct: 33 EHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLR 92
Query: 297 XXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLNEM 473
+P V + ++RAGF EV+R LA GV + ++L+ HL L ++
Sbjct: 93 RVQVTAALSADPAV-LGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQL 150
>AB048791-1|BAB13510.1| 221|Homo sapiens bHLH factor Hes4 protein.
Length = 221
Score = 81.0 bits (191), Expect = 3e-15
Identities = 46/119 (38%), Positives = 69/119 (57%), Gaps = 3/119 (2%)
Frame = +3
Query: 126 QYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV---XXXX 296
++RK KP++E++RRARIN L +LK L++ AL+ E +KLEKADILE+TV
Sbjct: 33 EHRKSSKPVMEKRRRARINESLAQLKTLILDALRKESSRHSKLEKADILEMTVRHLRSLR 92
Query: 297 XXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHRLNEM 473
+P V + ++RAGF EV+R LA GV + ++L+ HL L ++
Sbjct: 93 RVQVTAALSADPAV-LGKYRAGFHECLAEVNRFLAGCEGVPADVRSRLLGHLAACLRQL 150
>BC142687-1|AAI42688.1| 173|Homo sapiens HES2 protein protein.
Length = 173
Score = 74.5 bits (175), Expect = 3e-13
Identities = 40/120 (33%), Positives = 65/120 (54%)
Frame = +3
Query: 102 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 281
P+ + RK +KP+LE++RRARIN+ L +LK L++ L E N +KLEKAD+LE+T
Sbjct: 4 PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63
Query: 282 VXXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHR 461
V P + D +R G++ ++R L + ++ + +L+ HL R
Sbjct: 64 VRFLQELPASSWPTAAP-LPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRR 122
>BC132698-1|AAI32699.1| 173|Homo sapiens hairy and enhancer of
split 2 (Drosophila) protein.
Length = 173
Score = 74.5 bits (175), Expect = 3e-13
Identities = 40/120 (33%), Positives = 65/120 (54%)
Frame = +3
Query: 102 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 281
P+ + RK +KP+LE++RRARIN+ L +LK L++ L E N +KLEKAD+LE+T
Sbjct: 4 PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63
Query: 282 VXXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHR 461
V P + D +R G++ ++R L + ++ + +L+ HL R
Sbjct: 64 VRFLQELPASSWPTAAP-LPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRR 122
>AL031848-4|CAB46198.1| 173|Homo sapiens hairy and enhancer of
split 2 (Drosophila) protein.
Length = 173
Score = 74.5 bits (175), Expect = 3e-13
Identities = 40/120 (33%), Positives = 65/120 (54%)
Frame = +3
Query: 102 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELT 281
P+ + RK +KP+LE++RRARIN+ L +LK L++ L E N +KLEKAD+LE+T
Sbjct: 4 PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRENSNCSKLEKADVLEMT 63
Query: 282 VXXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHLGHR 461
V P + D +R G++ ++R L + ++ + +L+ HL R
Sbjct: 64 VRFLQELPASSWPTAAP-LPCDSYREGYSACVARLARVLPACRVLEPAVSARLLEHLWRR 122
>BC007939-1|AAH07939.1| 224|Homo sapiens hairy and enhancer of
split 6 (Drosophila) protein.
Length = 224
Score = 61.3 bits (142), Expect = 3e-09
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 311
RK KP++E+KRRARIN L EL+ L+ A E AKLE A++LELTV
Sbjct: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTVRRVQGVLRG 80
Query: 312 XXXXXN--PTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 452
+RF AG+ +EV +++ +D + +L+ HL
Sbjct: 81 RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHL 129
>AC016757-5|AAY24337.1| 224|Homo sapiens unknown protein.
Length = 224
Score = 61.3 bits (142), Expect = 3e-09
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 311
RK KP++E+KRRARIN L EL+ L+ A E AKLE A++LELTV
Sbjct: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTVRRVQGVLRG 80
Query: 312 XXXXXN--PTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 452
+RF AG+ +EV +++ +D + +L+ HL
Sbjct: 81 RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHL 129
>AB035179-1|BAA96082.1| 224|Homo sapiens HES6 protein.
Length = 224
Score = 61.3 bits (142), Expect = 3e-09
Identities = 38/109 (34%), Positives = 55/109 (50%), Gaps = 2/109 (1%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 311
RK KP++E+KRRARIN L EL+ L+ A E AKLE A++LELTV
Sbjct: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTVRRVQGVLRG 80
Query: 312 XXXXXN--PTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 452
+RF AG+ +EV +++ +D + +L+ HL
Sbjct: 81 RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHL 129
>AF260237-1|AAK51634.1| 222|Homo sapiens hairy/enhancer of split 6
protein.
Length = 222
Score = 58.8 bits (136), Expect = 1e-08
Identities = 37/109 (33%), Positives = 54/109 (49%), Gaps = 2/109 (1%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTVXXXXXXXXX 311
RK KP++E+KRRARIN L EL+ L+ A AKLE A++LELTV
Sbjct: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-------EAKLENAEVLELTVRRVQGVLRG 78
Query: 312 XXXXXN--PTVDVDRFRAGFTHAANEVSRCLASIPGVDVRLGTQLMTHL 452
+RF AG+ +EV +++ +D + +L+ HL
Sbjct: 79 RAREREQLQAEASERFAAGYIQCMHEVHTFVSTCQAIDATVAAELLNHL 127
>BT020068-1|AAV38871.1| 337|Homo sapiens hairy/enhancer-of-split
related with YRPW motif 2 protein.
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>BT020067-1|AAV38870.1| 337|Homo sapiens hairy/enhancer-of-split
related with YRPW motif 2 protein.
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>BC007707-1|AAH07707.1| 337|Homo sapiens hairy/enhancer-of-split
related with YRPW motif 2 protein.
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>AL078594-2|CAI20068.1| 291|Homo sapiens hairy/enhancer-of-split
related with YRPW motif 2 protein.
Length = 291
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 3 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 60
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 61 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 111
>AL078594-1|CAB87581.1| 337|Homo sapiens hairy/enhancer-of-split
related with YRPW motif 2 protein.
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>AJ249545-1|CAB56839.1| 337|Homo sapiens basic-helix-loop-helix
protein, bHLH protein.
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>AF311884-1|AAG31157.1| 337|Homo sapiens hairy-related
transcription factor 2 protein.
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>AF237949-1|AAF44781.1| 337|Homo sapiens GRIDLOCK protein.
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>AF232238-1|AAF37296.1| 337|Homo sapiens HES-related repressor
protein 1 HERP1 protein.
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>AF173901-1|AAF20173.1| 337|Homo sapiens basic helix-loop-helix
factor 1 protein.
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>AB044755-1|BAA96781.1| 337|Homo sapiens basic-helix-loop-helix
protein protein.
Length = 337
Score = 58.4 bits (135), Expect = 2e-08
Identities = 38/111 (34%), Positives = 60/111 (54%), Gaps = 4/111 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ +A + +G AKLEKA+IL++TV
Sbjct: 49 RKKRRGIIEKRRRDRINNSLSELRRLVPTAFEKQGS--AKLEKAEILQMTVDHLKMLQAT 106
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHL 452
+ +D GF EV+R L+S+ G+D L +L++HL
Sbjct: 107 GGKGYFDAHALAMDFMSIGFRECLTEVARYLSSVEGLDSSDPLRVRLVSHL 157
>BT020065-1|AAV38868.1| 304|Homo sapiens hairy/enhancer-of-split
related with YRPW motif 1 protein.
Length = 304
Score = 57.2 bits (132), Expect = 4e-08
Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 4/119 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ SA + +G AKLEKA+IL++TV
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGHRLNEMQ 476
+ +D GF EV+R L+ I G+D L +L++HL + ++ +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQRE 166
>BC001873-1|AAH01873.1| 304|Homo sapiens hairy/enhancer-of-split
related with YRPW motif 1 protein.
Length = 304
Score = 57.2 bits (132), Expect = 4e-08
Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 4/119 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ SA + +G AKLEKA+IL++TV
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGHRLNEMQ 476
+ +D GF EV+R L+ I G+D L +L++HL + ++ +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQRE 166
>AJ272214-1|CAB75715.1| 304|Homo sapiens HEY1 protein protein.
Length = 304
Score = 57.2 bits (132), Expect = 4e-08
Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 4/119 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ SA + +G AKLEKA+IL++TV
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGHRLNEMQ 476
+ +D GF EV+R L+ I G+D L +L++HL + ++ +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQRE 166
>AF311883-1|AAG31156.1| 304|Homo sapiens hairy-related
transcription factor 1 protein.
Length = 304
Score = 57.2 bits (132), Expect = 4e-08
Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 4/119 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ SA + +G AKLEKA+IL++TV
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGHRLNEMQ 476
+ +D GF EV+R L+ I G+D L +L++HL + ++ +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQRE 166
>AF254637-1|AAL06278.1| 304|Homo sapiens basic helix-loop-helix
protein OAF1 protein.
Length = 304
Score = 57.2 bits (132), Expect = 4e-08
Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 4/119 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ SA + +G AKLEKA+IL++TV
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGHRLNEMQ 476
+ +D GF EV+R L+ I G+D L +L++HL + ++ +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQRE 166
>AF232239-1|AAF37297.1| 304|Homo sapiens HES-related repressor
protein 2 HERP2 protein.
Length = 304
Score = 57.2 bits (132), Expect = 4e-08
Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 4/119 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ SA + +G AKLEKA+IL++TV
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGHRLNEMQ 476
+ +D GF EV+R L+ I G+D L +L++HL + ++ +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQRE 166
>AF176422-1|AAD51749.1| 304|Homo sapiens cardiovascular
helix-loop-helix factor 2 protein.
Length = 304
Score = 57.2 bits (132), Expect = 4e-08
Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 4/119 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ SA + +G AKLEKA+IL++TV
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGHRLNEMQ 476
+ +D GF EV+R L+ I G+D L +L++HL + ++ +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQRE 166
>AF151522-1|AAD38967.1| 304|Homo sapiens hairy and enhancer of
split related-1 protein.
Length = 304
Score = 57.2 bits (132), Expect = 4e-08
Identities = 39/119 (32%), Positives = 63/119 (52%), Gaps = 4/119 (3%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV--XXXXXXX 305
RK + ++E++RR RIN L EL+ L+ SA + +G AKLEKA+IL++TV
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQGS--AKLEKAEILQMTVDHLKMLHTA 107
Query: 306 XXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGHRLNEMQ 476
+ +D GF EV+R L+ I G+D L +L++HL + ++ +
Sbjct: 108 GGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQRE 166
>BC006087-1|AAH06087.1| 328|Homo sapiens hairy/enhancer-of-split
related with YRPW motif-like protein.
Length = 328
Score = 55.2 bits (127), Expect = 2e-07
Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
Frame = +3
Query: 108 PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 284
P S Q RK + ++E++RR RIN L EL+ L+ +A + +G +KLEKA++L++TV
Sbjct: 36 PSSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVD 93
Query: 285 -XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR---LGTQLMTHL 452
+ VD GF EV R L + G R + +L++HL
Sbjct: 94 HLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153
Query: 453 GHRLNEMQ 476
EM+
Sbjct: 154 NSYAAEME 161
>AJ272215-1|CAB75716.1| 328|Homo sapiens HEYL protein protein.
Length = 328
Score = 55.2 bits (127), Expect = 2e-07
Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
Frame = +3
Query: 108 PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 284
P S Q RK + ++E++RR RIN L EL+ L+ +A + +G +KLEKA++L++TV
Sbjct: 36 PSSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVD 93
Query: 285 -XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR---LGTQLMTHL 452
+ VD GF EV R L + G R + +L++HL
Sbjct: 94 HLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153
Query: 453 GHRLNEMQ 476
EM+
Sbjct: 154 NSYAAEME 161
>AF311885-1|AAG31158.1| 328|Homo sapiens hairy-related
transcription factor 3 protein.
Length = 328
Score = 55.2 bits (127), Expect = 2e-07
Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
Frame = +3
Query: 108 PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 284
P S Q RK + ++E++RR RIN L EL+ L+ +A + +G +KLEKA++L++TV
Sbjct: 36 PSSSQMQARKKRRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVD 93
Query: 285 -XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR---LGTQLMTHL 452
+ VD GF EV R L + G R + +L++HL
Sbjct: 94 HLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153
Query: 453 GHRLNEMQ 476
EM+
Sbjct: 154 NSYAAEME 161
>AL035404-1|CAI19572.1| 328|Homo sapiens hairy/enhancer-of-split
related with YRPW motif-like protein.
Length = 328
Score = 54.8 bits (126), Expect = 2e-07
Identities = 40/128 (31%), Positives = 62/128 (48%), Gaps = 5/128 (3%)
Frame = +3
Query: 108 PVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV- 284
P S Q RK + ++E++RR RIN L EL+ L+ +A + +G +KLEKA++L++TV
Sbjct: 36 PSSSQMQARKKHRGIIEKRRRDRINSSLSELRRLVPTAFEKQGS--SKLEKAEVLQMTVD 93
Query: 285 -XXXXXXXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR---LGTQLMTHL 452
+ VD GF EV R L + G R + +L++HL
Sbjct: 94 HLKMLHATGGTGFFDARALAVDFRSIGFRECLTEVIRYLGVLEGPSSRADPVRIRLLSHL 153
Query: 453 GHRLNEMQ 476
EM+
Sbjct: 154 NSYAAEME 161
>AK092437-1|BAC03890.1| 308|Homo sapiens protein ( Homo sapiens
cDNA FLJ35118 fis, clone PLACE6007436, highly similar to
Homo sapiens hairy and enhancer of split related-1
(HESR-1) ).
Length = 308
Score = 54.0 bits (124), Expect = 4e-07
Identities = 38/121 (31%), Positives = 63/121 (52%), Gaps = 6/121 (4%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSE--GENVAKLEKADILELTV--XXXXX 299
RK + ++E++RR RIN L EL+ L+ SA + + + AKLEKA+IL++TV
Sbjct: 50 RKRRRGIIEKRRRDRINNSLSELRRLVPSAFEKQVMEQGSAKLEKAEILQMTVDHLKMLH 109
Query: 300 XXXXXXXXXNPTVDVDRFRAGFTHAANEVSRCLASIPGVDVR--LGTQLMTHLGHRLNEM 473
+ +D GF EV+R L+ I G+D L +L++HL + ++
Sbjct: 110 TAGGKGYFDAHALAMDYRSLGFRECLAEVARYLSIIEGLDASDPLRVRLVSHLNNYASQR 169
Query: 474 Q 476
+
Sbjct: 170 E 170
>AK075040-1|BAC11368.1| 214|Homo sapiens protein ( Homo sapiens
cDNA FLJ90559 fis, clone OVARC1001049, weakly similar to
TRANSCRIPTION FACTOR HES-1 (C-HAIRY1). ).
Length = 214
Score = 50.8 bits (116), Expect = 4e-06
Identities = 28/51 (54%), Positives = 35/51 (68%)
Frame = +3
Query: 132 RKVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
RK KP++E+KRRARIN L EL+ L+ A E AKLE A++LELTV
Sbjct: 26 RKARKPLVEKKRRARINESLQELRLLLAGA-----EVQAKLENAEVLELTV 71
>AB049064-1|BAB39525.1| 225|Homo sapiens bHLH factor Hes7 protein.
Length = 225
Score = 50.8 bits (116), Expect = 4e-06
Identities = 23/50 (46%), Positives = 36/50 (72%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K++KP++E++RR RINR L+EL+ L++ + + KLEKA+ILE V
Sbjct: 14 KMLKPLVEKRRRDRINRSLEELRLLLLERTRDQNLRNPKLEKAEILEFAV 63
>DQ272660-1|ABB83829.1| 166|Homo sapiens HES5 protein.
Length = 166
Score = 43.2 bits (97), Expect = 7e-04
Identities = 22/50 (44%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
++ KP++E+ RR RIN +++LK L+ N +KLEKADILE+ V
Sbjct: 18 RLRKPVVEKMRRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAV 66
>AL031847-3|CAI19439.1| 180|Homo sapiens hairy and enhancer of
split 3 (Drosophila) protein.
Length = 180
Score = 41.5 bits (93), Expect = 0.002
Identities = 24/44 (54%), Positives = 30/44 (68%)
Frame = +3
Query: 153 LERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
+E+KRRARIN L++LK L+ S KLEKADILEL+V
Sbjct: 1 MEKKRRARINVSLEQLKSLL-EKHYSHQIRKRKLEKADILELSV 43
>BC012091-1|AAH12091.1| 76|Homo sapiens HES2 protein protein.
Length = 76
Score = 41.1 bits (92), Expect = 0.003
Identities = 19/44 (43%), Positives = 29/44 (65%)
Frame = +3
Query: 102 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSE 233
P+ + RK +KP+LE++RRARIN+ L +LK L++ L E
Sbjct: 4 PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRE 47
>AL031848-5|CAB46199.1| 76|Homo sapiens hairy and enhancer of
split 2 (Drosophila) protein.
Length = 76
Score = 41.1 bits (92), Expect = 0.003
Identities = 19/44 (43%), Positives = 29/44 (65%)
Frame = +3
Query: 102 PQPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSE 233
P+ + RK +KP+LE++RRARIN+ L +LK L++ L E
Sbjct: 4 PRRAGDAAELRKSLKPLLEKRRRARINQSLSQLKGLILPLLGRE 47
>EF015896-1|ABM64207.1| 482|Homo sapiens basic helix-loop-helix
domain-containing protein.
Length = 482
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 46 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93
>EF015895-1|ABM64206.1| 412|Homo sapiens basic helix-loop-helix
domain-containing protein.
Length = 412
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 54 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101
>CR456921-1|CAG33202.1| 412|Homo sapiens BHLHB2 protein.
Length = 412
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 54 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101
>BC082238-1|AAH82238.1| 412|Homo sapiens basic helix-loop-helix
domain containing, class B, 2 protein.
Length = 412
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 54 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101
>BC025968-1|AAH25968.1| 482|Homo sapiens basic helix-loop-helix
domain containing, class B, 3 protein.
Length = 482
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 46 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93
>AY665467-1|AAV54602.1| 482|Homo sapiens basic helix-loop-helix
protein 3 isoform 1 protein.
Length = 482
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 46 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93
>AF353635-1|AAK49525.1| 409|Homo sapiens bHLH transcription factor
DEC1 protein.
Length = 409
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 51 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 98
>AB044088-1|BAB21502.1| 482|Homo sapiens bHLH protein DEC2 protein.
Length = 482
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 46 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 93
>AB043885-1|BAB18565.1| 412|Homo sapiens bHLH transcriptional
factor DEC1 protein.
Length = 412
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 54 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101
>AB004066-1|BAA21720.1| 412|Homo sapiens DEC1 protein.
Length = 412
Score = 40.3 bits (90), Expect = 0.005
Identities = 21/50 (42%), Positives = 33/50 (66%)
Frame = +3
Query: 135 KVMKPMLERKRRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
K+ ++E+KRR RIN C+ +LK+L+ L+ + LEKA +LELT+
Sbjct: 54 KLPHRLIEKKRRDRINECIAQLKDLLPEHLKL--TTLGHLEKAVVLELTL 101
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 35.1 bits (77), Expect = 0.19
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +3
Query: 105 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 242
QPV R +Y+ ++K ++ K R R N L E +VSAL EN
Sbjct: 447 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 492
>AL670729-3|CAH71673.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 35.1 bits (77), Expect = 0.19
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +3
Query: 105 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 242
QPV R +Y+ ++K ++ K R R N L E +VSAL EN
Sbjct: 5831 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 5876
>AL359510-13|CAI15072.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 35.1 bits (77), Expect = 0.19
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +3
Query: 105 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 242
QPV R +Y+ ++K ++ K R R N L E +VSAL EN
Sbjct: 5831 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 5876
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 35.1 bits (77), Expect = 0.19
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +3
Query: 105 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 242
QPV R +Y+ ++K ++ K R R N L E +VSAL EN
Sbjct: 447 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 492
>AL353593-3|CAI19285.1| 6620|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 6620
Score = 35.1 bits (77), Expect = 0.19
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +3
Query: 105 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 242
QPV R +Y+ ++K ++ K R R N L E +VSAL EN
Sbjct: 5831 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 5876
>AJ314908-1|CAC85755.1| 1020|Homo sapiens obscurin protein.
Length = 1020
Score = 35.1 bits (77), Expect = 0.19
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +3
Query: 105 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 242
QPV R +Y+ ++K ++ K R R N L E +VSAL EN
Sbjct: 231 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 276
>AJ002535-1|CAC44768.1| 6620|Homo sapiens obscurin protein.
Length = 6620
Score = 35.1 bits (77), Expect = 0.19
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +3
Query: 105 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 242
QPV R +Y+ ++K ++ K R R N L E +VSAL EN
Sbjct: 5831 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 5876
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 35.1 bits (77), Expect = 0.19
Identities = 18/46 (39%), Positives = 25/46 (54%)
Frame = +3
Query: 105 QPVSRTYQYRKVMKPMLERKRRARINRCLDELKELMVSALQSEGEN 242
QPV R +Y+ ++K ++ K R R N L E +VSAL EN
Sbjct: 447 QPVERVQRYQALLKELIRNKARNRQNCALLEQAYAVVSALPQRAEN 492
>BC087840-1|AAH87840.1| 172|Homo sapiens HES5 protein protein.
Length = 172
Score = 34.3 bits (75), Expect = 0.34
Identities = 19/40 (47%), Positives = 25/40 (62%)
Frame = +3
Query: 165 RRARINRCLDELKELMVSALQSEGENVAKLEKADILELTV 284
RR RIN +++LK L+ N +KLEKADILE+ V
Sbjct: 2 RRDRINSSIEQLKLLLEQEFARHQPN-SKLEKADILEMAV 40
>BC032586-1|AAH32586.1| 363|Homo sapiens MXD3 protein protein.
Length = 363
Score = 29.9 bits (64), Expect = 7.3
Identities = 11/20 (55%), Positives = 17/20 (85%)
Frame = +3
Query: 153 LERKRRARINRCLDELKELM 212
LE++RRA++ RCL+ LK+ M
Sbjct: 65 LEKRRRAQLKRCLERLKQQM 84
>BC000745-1|AAH00745.1| 206|Homo sapiens MAX dimerization protein 3
protein.
Length = 206
Score = 29.9 bits (64), Expect = 7.3
Identities = 11/20 (55%), Positives = 17/20 (85%)
Frame = +3
Query: 153 LERKRRARINRCLDELKELM 212
LE++RRA++ RCL+ LK+ M
Sbjct: 65 LEKRRRAQLKRCLERLKQQM 84
>AK222579-1|BAD96299.1| 206|Homo sapiens MAX dimerization protein 3
variant protein.
Length = 206
Score = 29.9 bits (64), Expect = 7.3
Identities = 11/20 (55%), Positives = 17/20 (85%)
Frame = +3
Query: 153 LERKRRARINRCLDELKELM 212
LE++RRA++ RCL+ LK+ M
Sbjct: 65 LEKRRRAQLKRCLERLKQQM 84
>AK057034-1|BAB71352.1| 193|Homo sapiens protein ( Homo sapiens
cDNA FLJ32472 fis, clone SKNMC2000356, highly similar to
Mus musculus Max-interacting transcriptional repressor
(Mad3) ).
Length = 193
Score = 29.9 bits (64), Expect = 7.3
Identities = 11/20 (55%), Positives = 17/20 (85%)
Frame = +3
Query: 153 LERKRRARINRCLDELKELM 212
LE++RRA++ RCL+ LK+ M
Sbjct: 65 LEKRRRAQLKRCLERLKQQM 84
>AF114834-1|AAP97233.1| 206|Homo sapiens Myx protein.
Length = 206
Score = 29.9 bits (64), Expect = 7.3
Identities = 11/20 (55%), Positives = 17/20 (85%)
Frame = +3
Query: 153 LERKRRARINRCLDELKELM 212
LE++RRA++ RCL+ LK+ M
Sbjct: 65 LEKRRRAQLKRCLERLKQQM 84
>D26361-1|BAA05392.2| 1652|Homo sapiens KIAA0042 protein.
Length = 1652
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Frame = +3
Query: 9 VLRSSQTYALTH-DT-HTFNMSYEIAY-SVAEDGPQPVSRTYQYRKVMKPMLERKRRARI 179
V S + + H DT +N Y++++ S E P S+T Y K+ P+LER
Sbjct: 385 VFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEG-F 443
Query: 180 NRCL 191
N CL
Sbjct: 444 NTCL 447
>BC113742-1|AAI13743.1| 1648|Homo sapiens kinesin family member 14
protein.
Length = 1648
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Frame = +3
Query: 9 VLRSSQTYALTH-DT-HTFNMSYEIAY-SVAEDGPQPVSRTYQYRKVMKPMLERKRRARI 179
V S + + H DT +N Y++++ S E P S+T Y K+ P+LER
Sbjct: 381 VFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEG-F 439
Query: 180 NRCL 191
N CL
Sbjct: 440 NTCL 443
>AL445483-1|CAI17049.1| 1648|Homo sapiens kinesin family member 14
protein.
Length = 1648
Score = 29.5 bits (63), Expect = 9.6
Identities = 21/64 (32%), Positives = 31/64 (48%), Gaps = 3/64 (4%)
Frame = +3
Query: 9 VLRSSQTYALTH-DT-HTFNMSYEIAY-SVAEDGPQPVSRTYQYRKVMKPMLERKRRARI 179
V S + + H DT +N Y++++ S E P S+T Y K+ P+LER
Sbjct: 381 VFMSGKEITVEHPDTKQVYNFIYDVSFWSFDECHPHYASQTTVYEKLAAPLLERAFEG-F 439
Query: 180 NRCL 191
N CL
Sbjct: 440 NTCL 443
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 84,142,192
Number of Sequences: 237096
Number of extensions: 1622447
Number of successful extensions: 4633
Number of sequences better than 10.0: 72
Number of HSP's better than 10.0 without gapping: 4302
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4585
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6410414940
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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