Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12i17r
(767 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
Y13153-1|CAA73613.1| 486|Homo sapiens kynurenine 3-monooxygenas... 194 3e-49
AL591898-2|CAI13907.1| 486|Homo sapiens kynurenine 3-monooxygen... 194 3e-49
AL133390-2|CAM28228.1| 486|Homo sapiens kynurenine 3-monooxygen... 194 3e-49
AF056032-1|AAC62615.1| 486|Homo sapiens kynurenine 3-hydroxylas... 194 3e-49
AL591898-4|CAI13905.1| 473|Homo sapiens kynurenine 3-monooxygen... 176 8e-44
AL133390-4|CAM28226.1| 473|Homo sapiens kynurenine 3-monooxygen... 176 8e-44
AL591898-3|CAI13906.1| 452|Homo sapiens kynurenine 3-monooxygen... 141 6e-39
AL133390-3|CAM28227.1| 452|Homo sapiens kynurenine 3-monooxygen... 141 6e-39
BC005297-1|AAH05297.1| 407|Homo sapiens KMO protein protein. 159 8e-39
AL591898-1|CAI13903.1| 181|Homo sapiens kynurenine 3-monooxygen... 115 2e-25
AL133390-1|CAM28225.1| 181|Homo sapiens kynurenine 3-monooxygen... 115 2e-25
BC014483-1|AAH14483.1| 468|Homo sapiens coenzyme Q6 homolog, mo... 38 0.040
BC014181-1|AAH14181.1| 468|Homo sapiens coenzyme Q6 homolog, mo... 38 0.040
AK222965-1|BAD96685.1| 468|Homo sapiens CGI-10 protein isoform ... 38 0.040
AF132944-1|AAD27719.1| 468|Homo sapiens CGI-10 protein protein. 38 0.040
>Y13153-1|CAA73613.1| 486|Homo sapiens kynurenine 3-monooxygenase
protein.
Length = 486
Score = 194 bits (473), Expect = 3e-49
Identities = 90/204 (44%), Positives = 134/204 (65%)
Frame = -3
Query: 765 FHAITHFKS*ITEINY*RFFEKYFPDSIPLIGKQKLIADYFAGSASPLIAIKCRPYNVED 586
F F+ +T + FF+KYFPD+IPLIG++ L+ D+F A P+I++KC ++ +
Sbjct: 238 FMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS 297
Query: 585 KALIIGDAAHAVVPFYGQGMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAIS 406
+++GDAAHA+VPF+GQGMNAGFEDC + ++L K +DL+ L FS R D AIS
Sbjct: 298 HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAIS 357
Query: 405 DLAMYNYIEMRDLVTRPSYLLRKAIDDVIFWLMPKVWIPLYNSVTFSTIPYTQCIKNRQW 226
DL+MYNYIEMR V ++ +K ++ + +MP +IPLY VTFS I Y + ++ W
Sbjct: 358 DLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHW 417
Query: 225 QDKVLNRSLLFLGTVTSAVGAFYV 154
Q KV+N+ L FLG++ A+ + Y+
Sbjct: 418 QKKVINKGLFFLGSLI-AISSTYL 440
>AL591898-2|CAI13907.1| 486|Homo sapiens kynurenine 3-monooxygenase
(kynurenine 3-hydroxylase) protein.
Length = 486
Score = 194 bits (473), Expect = 3e-49
Identities = 90/204 (44%), Positives = 134/204 (65%)
Frame = -3
Query: 765 FHAITHFKS*ITEINY*RFFEKYFPDSIPLIGKQKLIADYFAGSASPLIAIKCRPYNVED 586
F F+ +T + FF+KYFPD+IPLIG++ L+ D+F A P+I++KC ++ +
Sbjct: 238 FMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS 297
Query: 585 KALIIGDAAHAVVPFYGQGMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAIS 406
+++GDAAHA+VPF+GQGMNAGFEDC + ++L K +DL+ L FS R D AIS
Sbjct: 298 HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAIS 357
Query: 405 DLAMYNYIEMRDLVTRPSYLLRKAIDDVIFWLMPKVWIPLYNSVTFSTIPYTQCIKNRQW 226
DL+MYNYIEMR V ++ +K ++ + +MP +IPLY VTFS I Y + ++ W
Sbjct: 358 DLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHW 417
Query: 225 QDKVLNRSLLFLGTVTSAVGAFYV 154
Q KV+N+ L FLG++ A+ + Y+
Sbjct: 418 QKKVINKGLFFLGSLI-AISSTYL 440
>AL133390-2|CAM28228.1| 486|Homo sapiens kynurenine 3-monooxygenase
(kynurenine 3-hydroxylase) protein.
Length = 486
Score = 194 bits (473), Expect = 3e-49
Identities = 90/204 (44%), Positives = 134/204 (65%)
Frame = -3
Query: 765 FHAITHFKS*ITEINY*RFFEKYFPDSIPLIGKQKLIADYFAGSASPLIAIKCRPYNVED 586
F F+ +T + FF+KYFPD+IPLIG++ L+ D+F A P+I++KC ++ +
Sbjct: 238 FMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS 297
Query: 585 KALIIGDAAHAVVPFYGQGMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAIS 406
+++GDAAHA+VPF+GQGMNAGFEDC + ++L K +DL+ L FS R D AIS
Sbjct: 298 HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAIS 357
Query: 405 DLAMYNYIEMRDLVTRPSYLLRKAIDDVIFWLMPKVWIPLYNSVTFSTIPYTQCIKNRQW 226
DL+MYNYIEMR V ++ +K ++ + +MP +IPLY VTFS I Y + ++ W
Sbjct: 358 DLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHW 417
Query: 225 QDKVLNRSLLFLGTVTSAVGAFYV 154
Q KV+N+ L FLG++ A+ + Y+
Sbjct: 418 QKKVINKGLFFLGSLI-AISSTYL 440
>AF056032-1|AAC62615.1| 486|Homo sapiens kynurenine 3-hydroxylase
protein.
Length = 486
Score = 194 bits (473), Expect = 3e-49
Identities = 90/204 (44%), Positives = 134/204 (65%)
Frame = -3
Query: 765 FHAITHFKS*ITEINY*RFFEKYFPDSIPLIGKQKLIADYFAGSASPLIAIKCRPYNVED 586
F F+ +T + FF+KYFPD+IPLIG++ L+ D+F A P+I++KC ++ +
Sbjct: 238 FMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS 297
Query: 585 KALIIGDAAHAVVPFYGQGMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAIS 406
+++GDAAHA+VPF+GQGMNAGFEDC + ++L K +DL+ L FS R D AIS
Sbjct: 298 HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAIS 357
Query: 405 DLAMYNYIEMRDLVTRPSYLLRKAIDDVIFWLMPKVWIPLYNSVTFSTIPYTQCIKNRQW 226
DL+MYNYIEMR V ++ +K ++ + +MP +IPLY VTFS I Y + ++ W
Sbjct: 358 DLSMYNYIEMRAHVNSSWFIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHW 417
Query: 225 QDKVLNRSLLFLGTVTSAVGAFYV 154
Q KV+N+ L FLG++ A+ + Y+
Sbjct: 418 QKKVINKGLFFLGSLI-AISSTYL 440
>AL591898-4|CAI13905.1| 473|Homo sapiens kynurenine 3-monooxygenase
(kynurenine 3-hydroxylase) protein.
Length = 473
Score = 176 bits (428), Expect = 8e-44
Identities = 87/204 (42%), Positives = 128/204 (62%)
Frame = -3
Query: 765 FHAITHFKS*ITEINY*RFFEKYFPDSIPLIGKQKLIADYFAGSASPLIAIKCRPYNVED 586
F F+ +T + FF+KYFPD+IPLIG++ L+ D+F A P+I++KC ++ +
Sbjct: 238 FMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS 297
Query: 585 KALIIGDAAHAVVPFYGQGMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAIS 406
+++GDAAHA+VPF+GQGMNAGFEDC + ++L K +DL+ L FS R D AIS
Sbjct: 298 HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAIS 357
Query: 405 DLAMYNYIEMRDLVTRPSYLLRKAIDDVIFWLMPKVWIPLYNSVTFSTIPYTQCIKNRQW 226
DL+MYNYIE K ++ + +MP +IPLY VTFS I Y + ++ W
Sbjct: 358 DLSMYNYIE-------------KNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHW 404
Query: 225 QDKVLNRSLLFLGTVTSAVGAFYV 154
Q KV+N+ L FLG++ A+ + Y+
Sbjct: 405 QKKVINKGLFFLGSLI-AISSTYL 427
>AL133390-4|CAM28226.1| 473|Homo sapiens kynurenine 3-monooxygenase
(kynurenine 3-hydroxylase) protein.
Length = 473
Score = 176 bits (428), Expect = 8e-44
Identities = 87/204 (42%), Positives = 128/204 (62%)
Frame = -3
Query: 765 FHAITHFKS*ITEINY*RFFEKYFPDSIPLIGKQKLIADYFAGSASPLIAIKCRPYNVED 586
F F+ +T + FF+KYFPD+IPLIG++ L+ D+F A P+I++KC ++ +
Sbjct: 238 FMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS 297
Query: 585 KALIIGDAAHAVVPFYGQGMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAIS 406
+++GDAAHA+VPF+GQGMNAGFEDC + ++L K +DL+ L FS R D AIS
Sbjct: 298 HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAIS 357
Query: 405 DLAMYNYIEMRDLVTRPSYLLRKAIDDVIFWLMPKVWIPLYNSVTFSTIPYTQCIKNRQW 226
DL+MYNYIE K ++ + +MP +IPLY VTFS I Y + ++ W
Sbjct: 358 DLSMYNYIE-------------KNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHW 404
Query: 225 QDKVLNRSLLFLGTVTSAVGAFYV 154
Q KV+N+ L FLG++ A+ + Y+
Sbjct: 405 QKKVINKGLFFLGSLI-AISSTYL 427
>AL591898-3|CAI13906.1| 452|Homo sapiens kynurenine 3-monooxygenase
(kynurenine 3-hydroxylase) protein.
Length = 452
Score = 141 bits (341), Expect(2) = 6e-39
Identities = 63/130 (48%), Positives = 90/130 (69%)
Frame = -3
Query: 765 FHAITHFKS*ITEINY*RFFEKYFPDSIPLIGKQKLIADYFAGSASPLIAIKCRPYNVED 586
F F+ +T + FF+KYFPD+IPLIG++ L+ D+F A P+I++KC ++ +
Sbjct: 238 FMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS 297
Query: 585 KALIIGDAAHAVVPFYGQGMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAIS 406
+++GDAAHA+VPF+GQGMNAGFEDC + ++L K +DL+ L FS R D AIS
Sbjct: 298 HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAIS 357
Query: 405 DLAMYNYIEM 376
DL+MYNYIE+
Sbjct: 358 DLSMYNYIEV 367
Score = 40.3 bits (90), Expect(2) = 6e-39
Identities = 18/44 (40%), Positives = 28/44 (63%)
Frame = -3
Query: 285 YNSVTFSTIPYTQCIKNRQWQDKVLNRSLLFLGTVTSAVGAFYV 154
Y VTFS I Y + ++ WQ KV+N+ L FLG++ A+ + Y+
Sbjct: 364 YIEVTFSRIRYHEAVQRWHWQKKVINKGLFFLGSLI-AISSTYL 406
>AL133390-3|CAM28227.1| 452|Homo sapiens kynurenine 3-monooxygenase
(kynurenine 3-hydroxylase) protein.
Length = 452
Score = 141 bits (341), Expect(2) = 6e-39
Identities = 63/130 (48%), Positives = 90/130 (69%)
Frame = -3
Query: 765 FHAITHFKS*ITEINY*RFFEKYFPDSIPLIGKQKLIADYFAGSASPLIAIKCRPYNVED 586
F F+ +T + FF+KYFPD+IPLIG++ L+ D+F A P+I++KC ++ +
Sbjct: 238 FMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS 297
Query: 585 KALIIGDAAHAVVPFYGQGMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAIS 406
+++GDAAHA+VPF+GQGMNAGFEDC + ++L K +DL+ L FS R D AIS
Sbjct: 298 HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAIS 357
Query: 405 DLAMYNYIEM 376
DL+MYNYIE+
Sbjct: 358 DLSMYNYIEV 367
Score = 40.3 bits (90), Expect(2) = 6e-39
Identities = 18/44 (40%), Positives = 28/44 (63%)
Frame = -3
Query: 285 YNSVTFSTIPYTQCIKNRQWQDKVLNRSLLFLGTVTSAVGAFYV 154
Y VTFS I Y + ++ WQ KV+N+ L FLG++ A+ + Y+
Sbjct: 364 YIEVTFSRIRYHEAVQRWHWQKKVINKGLFFLGSLI-AISSTYL 406
>BC005297-1|AAH05297.1| 407|Homo sapiens KMO protein protein.
Length = 407
Score = 159 bits (387), Expect = 8e-39
Identities = 78/183 (42%), Positives = 113/183 (61%)
Frame = -3
Query: 765 FHAITHFKS*ITEINY*RFFEKYFPDSIPLIGKQKLIADYFAGSASPLIAIKCRPYNVED 586
F F+ +T + FF+KYFPD+IPLIG++ L+ D+F A P+I++KC ++ +
Sbjct: 238 FMPFEEFEKLLTSNDVVDFFQKYFPDAIPLIGEKLLVQDFFLLPAQPMISVKCSSFHFKS 297
Query: 585 KALIIGDAAHAVVPFYGQGMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAIS 406
+++GDAAHA+VPF+GQGMNAGFEDC + ++L K +DL+ L FS R D AIS
Sbjct: 298 HCVLLGDAAHAIVPFFGQGMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAIS 357
Query: 405 DLAMYNYIEMRDLVTRPSYLLRKAIDDVIFWLMPKVWIPLYNSVTFSTIPYTQCIKNRQW 226
DL+MYNYIE K ++ + +MP +IPLY VTFS I Y + ++ W
Sbjct: 358 DLSMYNYIE-------------KNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHW 404
Query: 225 QDK 217
Q +
Sbjct: 405 QKR 407
>AL591898-1|CAI13903.1| 181|Homo sapiens kynurenine 3-monooxygenase
(kynurenine 3-hydroxylase) protein.
Length = 181
Score = 115 bits (277), Expect = 2e-25
Identities = 56/126 (44%), Positives = 80/126 (63%)
Frame = -3
Query: 531 GMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAISDLAMYNYIEMRDLVTRPS 352
GMNAGFEDC + ++L K +DL+ L FS R D AISDL+MYNYIEMR V
Sbjct: 1 GMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSW 60
Query: 351 YLLRKAIDDVIFWLMPKVWIPLYNSVTFSTIPYTQCIKNRQWQDKVLNRSLLFLGTVTSA 172
++ +K ++ + +MP +IPLY VTFS I Y + ++ WQ KV+N+ L FLG++ A
Sbjct: 61 FIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHWQKKVINKGLFFLGSLI-A 119
Query: 171 VGAFYV 154
+ + Y+
Sbjct: 120 ISSTYL 125
>AL133390-1|CAM28225.1| 181|Homo sapiens kynurenine 3-monooxygenase
(kynurenine 3-hydroxylase) protein.
Length = 181
Score = 115 bits (277), Expect = 2e-25
Identities = 56/126 (44%), Positives = 80/126 (63%)
Frame = -3
Query: 531 GMNAGFEDCTILNQLFQKHHDDLAKILKEFSDTRWEDTFAISDLAMYNYIEMRDLVTRPS 352
GMNAGFEDC + ++L K +DL+ L FS R D AISDL+MYNYIEMR V
Sbjct: 1 GMNAGFEDCLVFDELMDKFSNDLSLCLPVFSRLRIPDDHAISDLSMYNYIEMRAHVNSSW 60
Query: 351 YLLRKAIDDVIFWLMPKVWIPLYNSVTFSTIPYTQCIKNRQWQDKVLNRSLLFLGTVTSA 172
++ +K ++ + +MP +IPLY VTFS I Y + ++ WQ KV+N+ L FLG++ A
Sbjct: 61 FIFQKNMERFLHAIMPSTFIPLYTMVTFSRIRYHEAVQRWHWQKKVINKGLFFLGSLI-A 119
Query: 171 VGAFYV 154
+ + Y+
Sbjct: 120 ISSTYL 125
>BC014483-1|AAH14483.1| 468|Homo sapiens coenzyme Q6 homolog,
monooxygenase (S. cerevisiae) protein.
Length = 468
Score = 37.9 bits (84), Expect = 0.040
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = -3
Query: 594 VEDKALIIGDAAHAVVPFYGQGMNAGFEDCTIL 496
V + +IGDAAH V P GQG+N GF D + L
Sbjct: 357 VRPRVALIGDAAHRVHPLAGQGVNMGFGDISSL 389
>BC014181-1|AAH14181.1| 468|Homo sapiens coenzyme Q6 homolog,
monooxygenase (S. cerevisiae) protein.
Length = 468
Score = 37.9 bits (84), Expect = 0.040
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = -3
Query: 594 VEDKALIIGDAAHAVVPFYGQGMNAGFEDCTIL 496
V + +IGDAAH V P GQG+N GF D + L
Sbjct: 357 VRPRVALIGDAAHRVHPLAGQGVNMGFGDISSL 389
>AK222965-1|BAD96685.1| 468|Homo sapiens CGI-10 protein isoform a
variant protein.
Length = 468
Score = 37.9 bits (84), Expect = 0.040
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = -3
Query: 594 VEDKALIIGDAAHAVVPFYGQGMNAGFEDCTIL 496
V + +IGDAAH V P GQG+N GF D + L
Sbjct: 357 VRPRVALIGDAAHRVHPLAGQGVNMGFGDISSL 389
>AF132944-1|AAD27719.1| 468|Homo sapiens CGI-10 protein protein.
Length = 468
Score = 37.9 bits (84), Expect = 0.040
Identities = 17/33 (51%), Positives = 21/33 (63%)
Frame = -3
Query: 594 VEDKALIIGDAAHAVVPFYGQGMNAGFEDCTIL 496
V + +IGDAAH V P GQG+N GF D + L
Sbjct: 357 VRPRVALIGDAAHRVHPLAGQGVNMGFGDISSL 389
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 104,943,557
Number of Sequences: 237096
Number of extensions: 2178590
Number of successful extensions: 3460
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3374
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3457
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9255747988
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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