Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12i02f
(607 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D567C5 Cluster: PREDICTED: similar to CG3394-PB,... 87 4e-16
UniRef50_UPI000065F15A Cluster: Long-chain fatty acid transport ... 78 2e-13
UniRef50_Q4RHG9 Cluster: Chromosome 3 SCAF15050, whole genome sh... 76 8e-13
UniRef50_Q6PCB7 Cluster: Long-chain fatty acid transport protein... 69 9e-11
UniRef50_Q3HUW8 Cluster: Fatty acid transport protein 1b; n=1; S... 66 8e-10
UniRef50_Q8SXR7 Cluster: RE52015p; n=6; Endopterygota|Rep: RE520... 59 9e-08
UniRef50_Q7KVJ6 Cluster: CG30194-PD, isoform D; n=14; Bilateria|... 57 4e-07
UniRef50_Q32LR7 Cluster: Zgc:153860 protein; n=2; Danio rerio|Re... 56 5e-07
UniRef50_A7RYU2 Cluster: Predicted protein; n=1; Nematostella ve... 56 7e-07
UniRef50_UPI00015B49C7 Cluster: PREDICTED: similar to ENSANGP000... 50 3e-05
UniRef50_Q19878 Cluster: Putative uncharacterized protein; n=4; ... 49 7e-05
UniRef50_Q0AXV0 Cluster: Acyl-CoA synthase; n=1; Syntrophomonas ... 48 2e-04
UniRef50_Q5BYC7 Cluster: SJCHGC04794 protein; n=1; Schistosoma j... 48 2e-04
UniRef50_Q4K8J7 Cluster: FadD6; n=6; Pseudomonas|Rep: FadD6 - Ps... 47 3e-04
UniRef50_Q63CQ7 Cluster: Multifunctional nonribosomal peptide sy... 46 5e-04
UniRef50_UPI00015A5F99 Cluster: Very-long-chain acyl-CoA synthet... 44 0.003
UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C ... 43 0.005
UniRef50_UPI0000E49830 Cluster: PREDICTED: hypothetical protein;... 43 0.006
UniRef50_A6VYG2 Cluster: Amino acid adenylation domain; n=1; Mar... 42 0.011
UniRef50_UPI000051A513 Cluster: PREDICTED: similar to Fatty acid... 41 0.020
UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular orga... 41 0.020
UniRef50_A0NTU6 Cluster: Putative non-ribosomal peptide syntheta... 41 0.020
UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosip... 41 0.026
UniRef50_Q0AM92 Cluster: AMP-dependent synthetase and ligase; n=... 41 0.026
UniRef50_A1ZLW0 Cluster: Bacitracin synthetase 1 (BA1), putative... 41 0.026
UniRef50_Q3KFI5 Cluster: AMP-dependent synthetase and ligase; n=... 40 0.035
UniRef50_Q0TGG3 Cluster: Non-ribosomal peptide synthetase; n=5; ... 40 0.035
UniRef50_A0IT99 Cluster: Amino acid adenylation domain; n=1; Ser... 40 0.035
UniRef50_Q39GC1 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.080
UniRef50_Q2JC10 Cluster: AMP-dependent synthetase and ligase; n=... 39 0.080
UniRef50_A7ICE0 Cluster: Amino acid adenylation domain; n=1; Xan... 39 0.080
UniRef50_Q0AY10 Cluster: Non-ribosomal peptide synthetase module... 39 0.11
UniRef50_Q4T9T7 Cluster: Chromosome undetermined SCAF7502, whole... 38 0.14
UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide syntheta... 38 0.14
UniRef50_Q0S6F3 Cluster: Non-ribosomal peptide synthetase; n=2; ... 38 0.14
UniRef50_Q39TF1 Cluster: AMP-dependent synthetase and ligase; n=... 38 0.18
UniRef50_Q7DAG9 Cluster: Peptide synthetase, putative; n=10; Myc... 38 0.18
UniRef50_A4KUB7 Cluster: TlmIV; n=3; root|Rep: TlmIV - Streptoal... 38 0.24
UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep... 38 0.24
UniRef50_O68008 Cluster: Bacitracin synthetase 3 (BA3) [Includes... 38 0.24
UniRef50_Q89CJ0 Cluster: Blr7807 protein; n=15; Proteobacteria|R... 37 0.32
UniRef50_Q0SEC4 Cluster: Possible long-chain-fatty-acid-CoA liga... 37 0.32
UniRef50_Q0S7M5 Cluster: AMP-binding CoA ligase; n=1; Rhodococcu... 37 0.32
UniRef50_A3Z2Q3 Cluster: Acyl-CoA synthase; n=1; Synechococcus s... 37 0.32
UniRef50_A3PWM4 Cluster: AMP-dependent synthetase and ligase; n=... 37 0.32
UniRef50_Q1E7N4 Cluster: Putative uncharacterized protein; n=1; ... 37 0.32
UniRef50_O68007 Cluster: Bacitracin synthetase 2 (BA2) [Includes... 37 0.32
UniRef50_A1WPK7 Cluster: AMP-dependent synthetase and ligase; n=... 37 0.43
UniRef50_A1SK93 Cluster: AMP-dependent synthetase and ligase; n=... 37 0.43
UniRef50_Q2GZD3 Cluster: Putative uncharacterized protein; n=1; ... 37 0.43
UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibio... 36 0.56
UniRef50_Q4ZVI3 Cluster: Amino acid adenylation; n=3; Pseudomona... 36 0.56
UniRef50_Q5KZW0 Cluster: Long-chain fatty-acid-CoA ligase; n=6; ... 36 0.74
UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1; Clo... 36 0.74
UniRef50_A2R3M8 Cluster: Catalytic activity: polyketide synthase... 36 0.74
UniRef50_A1DC00 Cluster: Nonribosomal peptide synthase, putative... 36 0.74
UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine syn... 36 0.74
UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Re... 36 0.98
UniRef50_Q5DIP4 Cluster: PvdJ; n=19; root|Rep: PvdJ - Pseudomona... 36 0.98
UniRef50_A6FHU7 Cluster: O-succinylbenzoic acid--CoA ligase; n=1... 36 0.98
UniRef50_A3P7D6 Cluster: Non-ribosomal peptide synthase; n=34; B... 36 0.98
UniRef50_A0QH53 Cluster: Linear gramicidin synthetase subunit D;... 36 0.98
UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1; ... 35 1.3
UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4; Ph... 35 1.3
UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7; Pseudomona... 35 1.3
UniRef50_A6V024 Cluster: Amino acid adenylation domain; n=1; Pse... 35 1.3
UniRef50_A1E027 Cluster: Ibuprofen CoA ligase; n=2; cellular org... 35 1.3
UniRef50_UPI000023DA7C Cluster: hypothetical protein FG11395.1; ... 35 1.7
UniRef50_Q4ANX0 Cluster: O-succinylbenzoate-CoA ligase; n=2; Chl... 35 1.7
UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1; My... 35 1.7
UniRef50_Q06YY9 Cluster: Nonribosomal peptide synthetase; n=1; S... 35 1.7
UniRef50_A1SPU7 Cluster: AMP-dependent synthetase and ligase; n=... 35 1.7
UniRef50_Q08Y42 Cluster: AMP-dependent synthetase and ligase; n=... 34 2.3
UniRef50_A4STS1 Cluster: Non-ribosomal peptide synthetase module... 34 2.3
UniRef50_A3RXA3 Cluster: AMP-(Fatty)acid ligases; n=6; Burkholde... 34 2.3
UniRef50_Q8YTS1 Cluster: Multifunctional peptide synthetase; n=3... 34 3.0
UniRef50_Q4C3C0 Cluster: Non-ribosomal peptide synthase:Amino ac... 34 3.0
UniRef50_A6V359 Cluster: Linear gramicidin synthetase subunit C;... 34 3.0
UniRef50_A5A9U3 Cluster: Mps2 protein; n=2; Mycobacterium|Rep: M... 34 3.0
UniRef50_Q9NS00 Cluster: Glycoprotein-N-acetylgalactosamine 3-be... 34 3.0
UniRef50_Q7N848 Cluster: Similarities with peptide synthetase li... 33 4.0
UniRef50_Q6LGA3 Cluster: Hypothetical peptide synthetase; n=1; P... 33 4.0
UniRef50_Q84BC7 Cluster: NcpB; n=3; Cyanobacteria|Rep: NcpB - No... 33 4.0
UniRef50_Q333V2 Cluster: NRPS protein; n=1; Micromonospora sp. M... 33 4.0
UniRef50_Q2ANW8 Cluster: Non-ribosomal peptide synthase:Amino ac... 33 4.0
UniRef50_Q18ZS3 Cluster: AMP-dependent synthetase and ligase; n=... 33 4.0
UniRef50_A3KI35 Cluster: Putative peptide synthetase; n=1; Strep... 33 4.0
UniRef50_A4QTM3 Cluster: Putative uncharacterized protein; n=1; ... 33 4.0
UniRef50_P27743 Cluster: N-(5-amino-5-carboxypentanoyl)-L-cystei... 33 4.0
UniRef50_UPI000023F703 Cluster: hypothetical protein FG00042.1; ... 33 5.2
UniRef50_Q2SAB9 Cluster: Acyl-CoA synthetases (AMP-forming)/AMP-... 33 5.2
UniRef50_O31782 Cluster: Polyketide synthase of type I; n=2; Bac... 33 5.2
UniRef50_Q4PK62 Cluster: Predicted very-long-chain acyl-CoA synt... 33 5.2
UniRef50_Q4C639 Cluster: Amino acid adenylation; n=1; Crocosphae... 33 5.2
UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1;... 33 5.2
UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2; Cy... 33 5.2
UniRef50_O87314 Cluster: FxbC; n=5; Mycobacterium smegmatis|Rep:... 33 5.2
UniRef50_A6P629 Cluster: Nonribosomal peptide synthetase; n=1; M... 33 5.2
UniRef50_A5YBV1 Cluster: Fusaricidin synthetase; n=1; Paenibacil... 33 5.2
UniRef50_A3HJ78 Cluster: Amino acid adenylation domain; n=1; Pse... 33 5.2
UniRef50_A1RCH2 Cluster: Putative coenzyme A ligase; n=1; Arthro... 33 5.2
UniRef50_Q5D6D3 Cluster: Nonribosomal peptide synthetase 6; n=5;... 33 5.2
UniRef50_UPI0000E488E2 Cluster: PREDICTED: hypothetical protein;... 33 6.9
UniRef50_Q4ZV19 Cluster: Non-ribosomal peptide synthase:Amino ac... 33 6.9
UniRef50_Q140M1 Cluster: Putative long chain fatty acid CoA liga... 33 6.9
UniRef50_Q0SEL8 Cluster: Non-ribosomal peptide synthetase; n=1; ... 33 6.9
UniRef50_O07944 Cluster: Pristinamycin I synthase 3 and 4; n=2; ... 33 6.9
UniRef50_A3Y827 Cluster: 2,3-dihydroxybenzoate--[carrier protein... 33 6.9
UniRef50_Q6C6T2 Cluster: Similar to sp|P34244 Saccharomyces cere... 33 6.9
UniRef50_A1DJT7 Cluster: Polyketide synthase, putative; n=2; Tri... 33 6.9
UniRef50_A1CMH4 Cluster: AMP dependent ligase; n=7; Trichocomace... 33 6.9
UniRef50_Q6FBY9 Cluster: Putative acyl-CoA ligase; n=1; Acinetob... 32 9.2
UniRef50_Q0SEL9 Cluster: Non-ribosomal peptide synthetase; n=1; ... 32 9.2
UniRef50_Q0SA57 Cluster: Long-chain-fatty-acid--CoA ligase; n=8;... 32 9.2
UniRef50_Q0RMN6 Cluster: Putative non ribosomal peptide syntheta... 32 9.2
UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2; Fir... 32 9.2
UniRef50_A6DM14 Cluster: Cytochrome c5530 family protein; n=1; L... 32 9.2
UniRef50_A5UQX5 Cluster: AMP-dependent synthetase and ligase; n=... 32 9.2
UniRef50_A0QHN3 Cluster: Syringomycin synthetase; n=3; Mycobacte... 32 9.2
UniRef50_Q4DTW0 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
UniRef50_Q4WVX2 Cluster: Ubiquitin C-terminal hydrolase, putativ... 32 9.2
UniRef50_A7ESR0 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
UniRef50_O27872 Cluster: Putative uncharacterized protein; n=1; ... 32 9.2
>UniRef50_UPI0000D567C5 Cluster: PREDICTED: similar to CG3394-PB,
isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG3394-PB, isoform B - Tribolium castaneum
Length = 623
Score = 86.6 bits (205), Expect = 4e-16
Identities = 42/109 (38%), Positives = 64/109 (58%), Gaps = 1/109 (0%)
Frame = +2
Query: 284 VATLGAYLLTGDRYQWIYLWKKTHKRDF-LGLRVLLATMFRIWRWEKQGQSVVSRWAEIA 460
V L +LLT RY+W Y+ KT RD G+R + F++WR+EK Q+V + ++
Sbjct: 8 VILLSIFLLTNRRYRWFYIIYKTLGRDVRAGIRFTILN-FQLWRYEKTNQTVAKIFTKLV 66
Query: 461 KLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFMET 607
+P+K AF TF + +SN+IA YFK +GFK G+ +AL +E+
Sbjct: 67 AKHPQKVAFYFESEIWTFEDVDKYSNKIAHYFKNEGFKRGDAVALVLES 115
>UniRef50_UPI000065F15A Cluster: Long-chain fatty acid transport
protein 1 (EC 6.2.1.-) (Fatty acid transport protein 1)
(FATP-1) (Solute carrier family 27 member 1).; n=1;
Takifugu rubripes|Rep: Long-chain fatty acid transport
protein 1 (EC 6.2.1.-) (Fatty acid transport protein 1)
(FATP-1) (Solute carrier family 27 member 1). - Takifugu
rubripes
Length = 686
Score = 77.8 bits (183), Expect = 2e-13
Identities = 43/112 (38%), Positives = 66/112 (58%), Gaps = 2/112 (1%)
Frame = +2
Query: 278 SAVATLGAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATMFRIWRWEKQGQSVVSRWAEI 457
S A LG YL T +++ Y+ +T KRD GL VLL +WR+ + G +++S +A+
Sbjct: 9 SLAAGLGVYLGT-KTWKYFYIAARTAKRDLSGLCVLLRVKLSLWRYMRNGCNILSIFAQT 67
Query: 458 AKLYPEKKAFI--MGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFMET 607
K +P K A I TF Q ++ SN +A + + QG+ SG+V+ALFME+
Sbjct: 68 VKRHPNKPALIYEATGETWTFTQLDELSNAVAHWARAQGWVSGDVVALFMES 119
>UniRef50_Q4RHG9 Cluster: Chromosome 3 SCAF15050, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 3 SCAF15050, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 612
Score = 75.8 bits (178), Expect = 8e-13
Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 2/107 (1%)
Frame = +2
Query: 293 LGAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATMFRIWRWEKQGQSVVSRWAEIAKLYP 472
LG YL T +++ Y+ +T KRD GL VLL +WR+ + G +++S +A+ K +P
Sbjct: 1 LGVYLGT-KTWKYFYIAARTAKRDLNGLHVLLRVKLSLWRYMRSGSNILSIFAQTVKKHP 59
Query: 473 EKKAFI--MGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFMET 607
K A I TF Q ++ SN +A + + QG+ G+V+ALFME+
Sbjct: 60 NKPALIYEATGETWTFTQLDELSNAVAHWARAQGWVPGDVVALFMES 106
>UniRef50_Q6PCB7 Cluster: Long-chain fatty acid transport protein 1;
n=61; Euteleostomi|Rep: Long-chain fatty acid transport
protein 1 - Homo sapiens (Human)
Length = 646
Score = 68.9 bits (161), Expect = 9e-11
Identities = 40/129 (31%), Positives = 71/129 (55%), Gaps = 2/129 (1%)
Frame = +2
Query: 224 ALTTAGLGWLLRGSPTMMSAVATLGAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATMFR 403
++ + L WLL G P SA A LG Y+ +G ++++ + KT +RD GL VL+
Sbjct: 10 SVVSLALLWLL-GLPWTWSAAAALGVYVGSGG-WRFLRIVCKTARRDLFGLSVLIRVRLE 67
Query: 404 IWRWEKQGQSVVSRWAEIAKLYPEKKAFIMGD--RALTFRQGEDFSNRIAWYFKRQGFKS 577
+ R ++ G ++ + + + PE+ A + TF Q + +SN +A F++ GF
Sbjct: 68 LRRHQRAGHTIPRIFQAVVQRQPERLALVDAGTGECWTFAQLDAYSNAVANLFRQLGFAP 127
Query: 578 GEVIALFME 604
G+V+A+F+E
Sbjct: 128 GDVVAIFLE 136
>UniRef50_Q3HUW8 Cluster: Fatty acid transport protein 1b; n=1; Sus
scrofa|Rep: Fatty acid transport protein 1b - Sus scrofa
(Pig)
Length = 570
Score = 65.7 bits (153), Expect = 8e-10
Identities = 42/131 (32%), Positives = 71/131 (54%), Gaps = 2/131 (1%)
Frame = +2
Query: 218 SIALTTAGLGWLLRGSPTMMSAVATLGAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATM 397
S ++ + L WLL G P S A LG Y+ G ++++ + KT +RD GL VL+
Sbjct: 8 SASVASLVLLWLL-GLPWTWSTAAALGVYV-GGGGWRFLRIVCKTARRDLFGLSVLIRVR 65
Query: 398 FRIWRWEKQGQSVVSRWAEIAKLYPEKKAFI-MGDRAL-TFRQGEDFSNRIAWYFKRQGF 571
+ R ++ ++ + +A+ PE A + G A TF Q + +SN +A F++ GF
Sbjct: 66 LELRRHQRARHTIPQIFQAVARQQPEHLALVDAGSGACWTFAQLDAYSNAVANLFRQLGF 125
Query: 572 KSGEVIALFME 604
G+V+A+F+E
Sbjct: 126 VPGDVVAIFLE 136
>UniRef50_Q8SXR7 Cluster: RE52015p; n=6; Endopterygota|Rep: RE52015p
- Drosophila melanogaster (Fruit fly)
Length = 687
Score = 58.8 bits (136), Expect = 9e-08
Identities = 35/110 (31%), Positives = 58/110 (52%), Gaps = 1/110 (0%)
Frame = +2
Query: 281 AVATLGAYL-LTGDRYQWIYLWKKTHKRDFLGLRVLLATMFRIWRWEKQGQSVVSRWAEI 457
A TLGA + L +++ T RD + +A + R ++ G +V + +
Sbjct: 63 ASLTLGAVVALLLRNPTFVFALVMTASRDLKAFQRFVALNIYLLRKDRGGFTVARCFQDQ 122
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFMET 607
A+ P+K F+M DR L+F + +FS +IA YF +G + G+ +AL MET
Sbjct: 123 ARRRPKKTCFVMDDRHLSFAEALEFSQKIAGYFSDRGLERGDCVALLMET 172
>UniRef50_Q7KVJ6 Cluster: CG30194-PD, isoform D; n=14;
Bilateria|Rep: CG30194-PD, isoform D - Drosophila
melanogaster (Fruit fly)
Length = 714
Score = 56.8 bits (131), Expect = 4e-07
Identities = 31/106 (29%), Positives = 52/106 (49%)
Frame = +2
Query: 287 ATLGAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATMFRIWRWEKQGQSVVSRWAEIAKL 466
A L + LL ++W Y+ T RD + L + + I R E++ ++ +
Sbjct: 92 AALISILLVRPGWRWFYIAAVTTPRDTVALFAYIRVLLFIKRQERKNLNIGDIFESNVAR 151
Query: 467 YPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
P+K A + + TFRQ + SNR+A F G+K G+V+ L +E
Sbjct: 152 QPDKLAIVSESQQWTFRQVNEHSNRVANVFHSHGYKKGDVVGLLLE 197
>UniRef50_Q32LR7 Cluster: Zgc:153860 protein; n=2; Danio rerio|Rep:
Zgc:153860 protein - Danio rerio (Zebrafish)
(Brachydanio rerio)
Length = 156
Score = 56.4 bits (130), Expect = 5e-07
Identities = 33/90 (36%), Positives = 54/90 (60%)
Frame = +2
Query: 221 IALTTAGLGWLLRGSPTMMSAVATLGAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATMF 400
+AL AGL L G P S V+ LG YL +G ++++Y+ +T KRD +GL+VLL F
Sbjct: 24 VALIIAGLLSAL-GVPWFWSLVSLLGVYLCSGG-WRFVYVAVRTAKRDLIGLQVLLRVKF 81
Query: 401 RIWRWEKQGQSVVSRWAEIAKLYPEKKAFI 490
+ ++ + ++ S +A+ L+PEK A +
Sbjct: 82 YMRQYIRNRSTIPSLFAQRVALHPEKAALV 111
>UniRef50_A7RYU2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 642
Score = 56.0 bits (129), Expect = 7e-07
Identities = 30/104 (28%), Positives = 53/104 (50%)
Frame = +2
Query: 293 LGAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATMFRIWRWEKQGQSVVSRWAEIAKLYP 472
+ +L +G R + ++ KT RD + + + + + + A P
Sbjct: 33 MAVFLCSGGR-NFPRVFFKTILRDLKAIIAFTIVQLKCRYYNYKNVIMADLFESTAASLP 91
Query: 473 EKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
K AF+ ++ TF++ ++F+NRIA YFK QG+ G+VIAL +E
Sbjct: 92 NKPAFVFEGKSWTFKEADEFANRIANYFKSQGYAKGDVIALILE 135
>UniRef50_UPI00015B49C7 Cluster: PREDICTED: similar to
ENSANGP00000012858; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000012858 - Nasonia
vitripennis
Length = 653
Score = 50.4 bits (115), Expect = 3e-05
Identities = 30/90 (33%), Positives = 44/90 (48%)
Frame = +2
Query: 332 IYLWKKTHKRDFLGLRVLLATMFRIWRWEKQGQSVVSRWAEIAKLYPEKKAFIMGDRALT 511
IY+ +T RD L + ++ K +V+ + E A+LYP K FI R T
Sbjct: 51 IYIILRTLPRDIKFLYRYVNADRETRQFVKNNSTVMKLFVERARLYPNKPCFIFEGRTWT 110
Query: 512 FRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
+ +SNRIA FK G+ G+ +AL M
Sbjct: 111 NADIDKYSNRIAAVFKNAGYVKGDAVALIM 140
>UniRef50_Q19878 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 684
Score = 49.2 bits (112), Expect = 7e-05
Identities = 33/113 (29%), Positives = 56/113 (49%), Gaps = 2/113 (1%)
Frame = +2
Query: 272 MMSAVATLGAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATMFRIWRWEKQGQSVVSRWA 451
+++ V L ++ GD +IY T RD GL +++ +W Q + + +
Sbjct: 60 ILAGVLILYITVVHGD---FIYRSYLTLNRDLTGLALIIEVKIDLWWRLHQNKGIHELFL 116
Query: 452 EIAKLYPEKKAFI--MGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
+I K P K A I + T+ + NR A YF+ G++SG+V+AL+ME
Sbjct: 117 DIVKKNPNKPAMIDIETNTTETYAEFNAHCNRYANYFQGLGYRSGDVVALYME 169
>UniRef50_Q0AXV0 Cluster: Acyl-CoA synthase; n=1; Syntrophomonas
wolfei subsp. wolfei str. Goettingen|Rep: Acyl-CoA
synthase - Syntrophomonas wolfei subsp. wolfei (strain
Goettingen)
Length = 590
Score = 48.0 bits (109), Expect = 2e-04
Identities = 19/44 (43%), Positives = 31/44 (70%)
Frame = +2
Query: 473 EKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
EK A I GDR +++ Q +NR A +F+++GFK G+V++L M+
Sbjct: 38 EKTALIYGDRYISYEQFNQMANRYAHFFQQEGFKKGDVVSLLMD 81
>UniRef50_Q5BYC7 Cluster: SJCHGC04794 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC04794 protein - Schistosoma
japonicum (Blood fluke)
Length = 189
Score = 48.0 bits (109), Expect = 2e-04
Identities = 31/100 (31%), Positives = 54/100 (54%), Gaps = 2/100 (2%)
Frame = +2
Query: 314 GDRYQWIYLWKKTHKRDFLGLRVLLATMFRI-W-RWEKQGQSVVSRWAEIAKLYPEKKAF 487
G RYQ ++ T RD +GL+ + I W +W K+ + + + + + K EK A
Sbjct: 59 GWRYQRVFFL--TILRDLIGLKCFIMVRLSILWLQWTKRTFADMFK-STVKKRGSEKVAI 115
Query: 488 IMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFMET 607
++ TF Q + +SN++A Y + GFK G+++ LFM +
Sbjct: 116 YFENQVWTFGQLDAYSNKVANYLVKCGFKRGDILLLFMNS 155
>UniRef50_Q4K8J7 Cluster: FadD6; n=6; Pseudomonas|Rep: FadD6 -
Pseudomonas fluorescens (strain Pf-5 / ATCC BAA-477)
Length = 737
Score = 47.2 bits (107), Expect = 3e-04
Identities = 20/45 (44%), Positives = 30/45 (66%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
PE A + GDR L++ Q ++NRIA Y + QG G+V+A+F+E
Sbjct: 183 PEGPALLYGDRVLSYAQVNQWANRIAAYLQEQGIGKGDVLAIFIE 227
>UniRef50_Q63CQ7 Cluster: Multifunctional nonribosomal peptide
synthetase; n=1; Bacillus cereus E33L|Rep:
Multifunctional nonribosomal peptide synthetase -
Bacillus cereus (strain ZK / E33L)
Length = 2543
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/55 (40%), Positives = 33/55 (60%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
SV+ + K +P KKA IMGD+++TF + + SNR+A +G K V+AL
Sbjct: 460 SVIDSFYANVKNWPNKKALIMGDKSMTFTELNELSNRLASKLISKGIKQNSVVAL 514
>UniRef50_UPI00015A5F99 Cluster: Very-long-chain acyl-CoA synthetase
(EC 6.2.1.-) (VLCS) (Very-long- chain-fatty-acid-CoA
ligase) (VLACS) (THCA-CoA ligase) (Fatty-acid- coenzyme
A ligase, very long-chain 1) (Long-chain-fatty-acid--CoA
ligase) (EC 6.2.1.3) (Fatty acid transport protein 2);
n=3; Danio rerio|Rep: Very-long-chain acyl-CoA
synthetase (EC 6.2.1.-) (VLCS) (Very-long-
chain-fatty-acid-CoA ligase) (VLACS) (THCA-CoA ligase)
(Fatty-acid- coenzyme A ligase, very long-chain 1)
(Long-chain-fatty-acid--CoA ligase) (EC 6.2.1.3) (Fatty
acid transport protein 2) - Danio rerio
Length = 584
Score = 44.0 bits (99), Expect = 0.003
Identities = 20/56 (35%), Positives = 35/56 (62%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALF 598
S + R+AE+A+ +P+K + GD T+R + SNR+A + +SG+++ALF
Sbjct: 56 STLERFAEVARKHPDKLFIVFGDERYTYRDADRISNRLANALRD---RSGQIVALF 108
>UniRef50_Q70LM5 Cluster: Linear gramicidin synthetase subunit C
[Includes: ATP-dependent valine adenylase (ValA) (Valine
activase); ATP-dependent D-valine adenylase (D-ValA)
(D-valine activase); Valine racemase [ATP-hydrolyzing]
(EC 5.1.1.-); ATP-dependent tryptophan adenylase (TrpA)
(Tryptophan activase); ATP-dependent D-leucine adenylase
(D-LeuA) (D-leucine activase); Leucine racemase
[ATP-hydrolyzing] (EC 5.1.1.-); ATP- dependent
tryptophan/phenylalanine/tyrosine adenylase
(Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine
activase); ATP-dependent D-leucine adenylase (D-LeuA)
(D-leucine activase); Leucine racemase [ATP- hydrolyzing]
(EC 5.1.1.-)]; n=11; cellular organisms|Rep: Linear
gramicidin synthetase subunit C [Includes: ATP-dependent
valine adenylase (ValA) (Valine activase); ATP-dependent
D-valine adenylase (D-ValA) (D-valine activase); Valine
racemase [ATP-hydrolyzing] (EC 5.1.1.-); ATP-dependent
tryptophan adenylase (TrpA) (Tryptophan activase);
ATP-dependent D-leucine adenylase (D-LeuA) (D-leucine
activase); Leucine racemase [ATP-hydrolyzing] (EC
5.1.1.-); ATP- dependent
tryptophan/phenylalanine/tyrosine adenylase
(Trp/Phe/TyrA) (Tryptophan/phenylalanine/tyrosine
activase); ATP-dependent D-leucine adenylase (D-LeuA)
(D-leucine activase); Leucine racemase [ATP- hydrolyzing]
(EC 5.1.1.-)] - Brevibacillus parabrevis
Length = 7756
Score = 43.2 bits (97), Expect = 0.005
Identities = 18/53 (33%), Positives = 36/53 (67%)
Frame = +2
Query: 446 WAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
+AE A YPE+ A + GD+ LT+ + + +N++A Y ++QG ++G ++ L ++
Sbjct: 1540 FAETAARYPERIAAVAGDQQLTYAELDTKANQLANYLQKQGVEAGTLVGLCVD 1592
Score = 42.3 bits (95), Expect = 0.009
Identities = 19/59 (32%), Positives = 39/59 (66%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
++V +AE A +PE+ A + GD+ LT+ + E +N++A Y ++QG ++G ++ L ++
Sbjct: 468 KTVHQLFAETAARHPERIAAVAGDQQLTYAELEARANQLANYLQKQGVEAGTLVGLCVD 526
>UniRef50_UPI0000E49830 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 567
Score = 42.7 bits (96), Expect = 0.006
Identities = 18/49 (36%), Positives = 31/49 (63%)
Frame = +2
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
A+ YP+K A ++ D+ T R E +SN +A F +G++ G+ +AL M+
Sbjct: 10 AERYPDKLALVLDDQKWTLRDLEMYSNAVANLFFERGYQKGDTVALLMD 58
>UniRef50_A6VYG2 Cluster: Amino acid adenylation domain; n=1;
Marinomonas sp. MWYL1|Rep: Amino acid adenylation domain
- Marinomonas sp. MWYL1
Length = 6404
Score = 41.9 bits (94), Expect = 0.011
Identities = 17/45 (37%), Positives = 30/45 (66%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
PEK A ++GD+ ++++ E+ +NR+A Y QG GE I L+++
Sbjct: 4205 PEKTALVIGDQRISYQLLEEKANRLARYLISQGVSEGECIGLYLD 4249
>UniRef50_UPI000051A513 Cluster: PREDICTED: similar to Fatty acid
(long chain) transport protein CG7400-PA, isoform A;
n=1; Apis mellifera|Rep: PREDICTED: similar to Fatty
acid (long chain) transport protein CG7400-PA, isoform A
- Apis mellifera
Length = 648
Score = 41.1 bits (92), Expect = 0.020
Identities = 24/90 (26%), Positives = 43/90 (47%)
Frame = +2
Query: 332 IYLWKKTHKRDFLGLRVLLATMFRIWRWEKQGQSVVSRWAEIAKLYPEKKAFIMGDRALT 511
+Y+ K RD L + I + ++ +V + + + K P+K F D+ T
Sbjct: 52 LYVMIKILPRDIRFLYRAITAEKEIKKHDRNNVTVPTIFMKRMKRNPQKPCFFFEDQIWT 111
Query: 512 FRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
F +SN+IA F++ G+ G+ +AL M
Sbjct: 112 FSDVNKYSNQIANVFQKAGYVKGDAVALMM 141
>UniRef50_Q9RLP6 Cluster: Peptide synthetase; n=18; cellular
organisms|Rep: Peptide synthetase - Mycobacterium
smegmatis
Length = 5990
Score = 41.1 bits (92), Expect = 0.020
Identities = 19/58 (32%), Positives = 35/58 (60%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
+S+ + +AE + P+ A GDR+ T+R+ ++ SNR+A +G K GE +A+ +
Sbjct: 1956 ESIPASFAESVRRVPDAVALSCGDRSWTYRELDEASNRMAHLLAGRGAKPGERVAMLL 2013
Score = 36.7 bits (81), Expect = 0.43
Identities = 17/57 (29%), Positives = 31/57 (54%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
++ + +AE P+ A + GDR+ T+R+ ++ SNR+A G K G +A +
Sbjct: 3473 TIPALFAEQVVRAPDAVALVSGDRSWTYRELDEASNRLAHVLAEHGAKPGATVAFLI 3529
>UniRef50_A0NTU6 Cluster: Putative non-ribosomal peptide synthetase;
n=1; Stappia aggregata IAM 12614|Rep: Putative
non-ribosomal peptide synthetase - Stappia aggregata IAM
12614
Length = 4579
Score = 41.1 bits (92), Expect = 0.020
Identities = 21/55 (38%), Positives = 30/55 (54%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
SV +A + P A IM LTF + + +NR+AWY R+G SG ++AL
Sbjct: 43 SVRELFARQVQSKPGATALIMPGSVLTFEELDRKANRVAWYLIRRGIGSGNIVAL 97
>UniRef50_Q0LP24 Cluster: Amino acid adenylation; n=1; Herpetosiphon
aurantiacus ATCC 23779|Rep: Amino acid adenylation -
Herpetosiphon aurantiacus ATCC 23779
Length = 2419
Score = 40.7 bits (91), Expect = 0.026
Identities = 16/58 (27%), Positives = 38/58 (65%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
++ S +A A+ +P +A + D++LT+++ E +SN++A + G S +++A+++E
Sbjct: 434 TIPSLFAAQAQQHPTAQAVVFEDQSLTYQELEGYSNQLALQLREHGAASEQIVAIYLE 491
>UniRef50_Q0AM92 Cluster: AMP-dependent synthetase and ligase; n=1;
Maricaulis maris MCS10|Rep: AMP-dependent synthetase and
ligase - Maricaulis maris (strain MCS10)
Length = 598
Score = 40.7 bits (91), Expect = 0.026
Identities = 16/45 (35%), Positives = 30/45 (66%)
Frame = +2
Query: 467 YPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
+P++ I+ + +++RQ + F+NR+A + QG K G+ +ALFM
Sbjct: 46 FPDRPMAILDEGEISYRQFDAFANRVANWALEQGLKPGDTVALFM 90
>UniRef50_A1ZLW0 Cluster: Bacitracin synthetase 1 (BA1), putative;
n=1; Microscilla marina ATCC 23134|Rep: Bacitracin
synthetase 1 (BA1), putative - Microscilla marina ATCC
23134
Length = 1301
Score = 40.7 bits (91), Expect = 0.026
Identities = 25/75 (33%), Positives = 39/75 (52%)
Frame = +2
Query: 383 LLATMFRIWRWEKQGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKR 562
LLA RI + ++VVS + PE A I+GD LT++ + SN++A Y
Sbjct: 436 LLAAPQRI-EPQYNNETVVSLFETQVDQTPEAVAAILGDDCLTYQALNEKSNQMAHYLIE 494
Query: 563 QGFKSGEVIALFMET 607
G + G+ + L+M T
Sbjct: 495 NGVRQGDYVGLYMHT 509
>UniRef50_Q3KFI5 Cluster: AMP-dependent synthetase and ligase; n=6;
Gammaproteobacteria|Rep: AMP-dependent synthetase and
ligase - Pseudomonas fluorescens (strain PfO-1)
Length = 612
Score = 40.3 bits (90), Expect = 0.035
Identities = 18/45 (40%), Positives = 28/45 (62%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
PE A + G+ L++ Q ++NRIA Y QG G+V+A+F+E
Sbjct: 58 PEGPALLSGEVVLSYSQVNQWANRIAHYLIGQGIGKGDVVAVFIE 102
>UniRef50_Q0TGG3 Cluster: Non-ribosomal peptide synthetase; n=5;
Escherichia coli|Rep: Non-ribosomal peptide synthetase -
Escherichia coli O6:K15:H31 (strain 536 / UPEC)
Length = 1455
Score = 40.3 bits (90), Expect = 0.035
Identities = 19/58 (32%), Positives = 34/58 (58%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
S SR+A + ++ A I +++LT+RQ +D R+A Y ++QG G+V+ + E
Sbjct: 449 SFTSRFAAQVVEHGDRTALIDNEQSLTYRQLDDAVERVARYLRQQGIGRGQVVGIIAE 506
>UniRef50_A0IT99 Cluster: Amino acid adenylation domain; n=1;
Serratia proteamaculans 568|Rep: Amino acid adenylation
domain - Serratia proteamaculans 568
Length = 570
Score = 40.3 bits (90), Expect = 0.035
Identities = 18/56 (32%), Positives = 33/56 (58%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
QSV+ + + PE A + ++ LT+RQ +D SN++ Y ++QG + G+ + L
Sbjct: 3 QSVLDYFIQQVTYSPEALAIVSHNKRLTYRQLDDASNQLCGYLQQQGVRPGDCVPL 58
>UniRef50_Q39GC1 Cluster: AMP-dependent synthetase and ligase; n=3;
Burkholderiales|Rep: AMP-dependent synthetase and ligase
- Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 561
Score = 39.1 bits (87), Expect = 0.080
Identities = 20/44 (45%), Positives = 27/44 (61%)
Frame = +2
Query: 449 AEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSG 580
AE A+ P+K AFI R LTFR+ ++ S+R+A R G K G
Sbjct: 38 AETARRLPDKAAFIADGRTLTFRELDEESDRLAAALVRLGLKPG 81
>UniRef50_Q2JC10 Cluster: AMP-dependent synthetase and ligase; n=1;
Frankia sp. CcI3|Rep: AMP-dependent synthetase and
ligase - Frankia sp. (strain CcI3)
Length = 526
Score = 39.1 bits (87), Expect = 0.080
Identities = 19/55 (34%), Positives = 32/55 (58%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
++ + W IA P + A I GD+A T+ Q + S +A +R G ++G+V+AL
Sbjct: 6 TLAALWQRIAAQQPHQTALIHGDQAWTWAQFDAASAALARTLRRHGVQAGQVVAL 60
>UniRef50_A7ICE0 Cluster: Amino acid adenylation domain; n=1;
Xanthobacter autotrophicus Py2|Rep: Amino acid
adenylation domain - Xanthobacter sp. (strain Py2)
Length = 1405
Score = 39.1 bits (87), Expect = 0.080
Identities = 18/59 (30%), Positives = 35/59 (59%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
Q + +++ A+ P+ A +M +R +T+ + E +NRIA +R+G K ++A+ ME
Sbjct: 422 QLIHDAFSDWAERQPDAPALLMRERVVTYGEMERLTNRIAHGLRRRGVKPNTLVAVMME 480
>UniRef50_Q0AY10 Cluster: Non-ribosomal peptide synthetase modules and
related proteins-like protein; n=1; Syntrophomonas wolfei
subsp. wolfei str. Goettingen|Rep: Non-ribosomal peptide
synthetase modules and related proteins-like protein -
Syntrophomonas wolfei subsp. wolfei (strain Goettingen)
Length = 2638
Score = 38.7 bits (86), Expect = 0.11
Identities = 20/72 (27%), Positives = 37/72 (51%)
Frame = +2
Query: 386 LATMFRIWRWEKQGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQ 565
L F W + + + E A L+P+K A I GD L+FR+ + +NR+A +
Sbjct: 1641 LLESFNQTAWPVRDIPLAHLFEEQAALHPDKVAVIAGDERLSFRELNERANRVANSLIEK 1700
Query: 566 GFKSGEVIALFM 601
G +S +++ + +
Sbjct: 1701 GIQSEQMVGIML 1712
>UniRef50_Q4T9T7 Cluster: Chromosome undetermined SCAF7502, whole
genome shotgun sequence; n=2; Tetraodontidae|Rep:
Chromosome undetermined SCAF7502, whole genome shotgun
sequence - Tetraodon nigroviridis (Green puffer)
Length = 689
Score = 38.3 bits (85), Expect = 0.14
Identities = 26/91 (28%), Positives = 45/91 (49%), Gaps = 2/91 (2%)
Frame = +2
Query: 335 YLWKKTHKRDFLGLRVL-LATMFRIWRWEKQGQSVVSRWAEIAKLYPEKKAFIMGDRALT 511
YLW+ F L++L ++R + +V+ R+ + A+ P+K + R T
Sbjct: 18 YLWRDL----FFLLKILRYGLKLELYRLTSRVCTVLDRFVQQAQRIPDKPFVVHDGRVHT 73
Query: 512 FRQGEDFSNRIAWYF-KRQGFKSGEVIALFM 601
+R + SNR+A F R G K G+ +A+ M
Sbjct: 74 YRDVDRRSNRLAQVFHHRAGLKKGDCVAVLM 104
>UniRef50_Q8XS39 Cluster: Probable non ribosomal peptide synthetase
protein; n=2; Proteobacteria|Rep: Probable non ribosomal
peptide synthetase protein - Ralstonia solanacearum
(Pseudomonas solanacearum)
Length = 5953
Score = 38.3 bits (85), Expect = 0.14
Identities = 16/45 (35%), Positives = 26/45 (57%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
PE A G+R L++R +NR+AW + G K G+ +A+ +E
Sbjct: 575 PEAIAIEQGERQLSYRALNALANRLAWRLREAGVKPGDRVAILLE 619
>UniRef50_Q0S6F3 Cluster: Non-ribosomal peptide synthetase; n=2;
cellular organisms|Rep: Non-ribosomal peptide synthetase
- Rhodococcus sp. (strain RHA1)
Length = 8939
Score = 38.3 bits (85), Expect = 0.14
Identities = 19/70 (27%), Positives = 39/70 (55%), Gaps = 5/70 (7%)
Frame = +2
Query: 410 RWEKQG-----QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFK 574
RW ++G Q+VV +A +A P+ A + GD LT+ + ++ +NR+A +G
Sbjct: 1801 RWNREGVTADAQTVVELFARVAASTPDATAVVCGDETLTYGELDEQANRLARLLIAEGVG 1860
Query: 575 SGEVIALFME 604
+ ++A+ ++
Sbjct: 1861 TESLVAVMVD 1870
>UniRef50_Q39TF1 Cluster: AMP-dependent synthetase and ligase; n=1;
Geobacter metallireducens GS-15|Rep: AMP-dependent
synthetase and ligase - Geobacter metallireducens
(strain GS-15 / ATCC 53774 / DSM 7210)
Length = 517
Score = 37.9 bits (84), Expect = 0.18
Identities = 18/47 (38%), Positives = 25/47 (53%)
Frame = +2
Query: 461 KLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
KL+P K A I GDR T+R+ D NR+A G K G+ + +
Sbjct: 12 KLFPTKSAIIDGDRRFTYREAGDRWNRLANVLVDCGLKKGDCLGFLL 58
>UniRef50_Q7DAG9 Cluster: Peptide synthetase, putative; n=10;
Mycobacterium tuberculosis complex|Rep: Peptide
synthetase, putative - Mycobacterium tuberculosis
Length = 2520
Score = 37.9 bits (84), Expect = 0.18
Identities = 19/52 (36%), Positives = 32/52 (61%)
Frame = +2
Query: 449 AEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
A++A++ PE +A GD ++T+R+ ++ SNR+A G GE +AL E
Sbjct: 1508 AQVARI-PEAEAVCCGDASMTYRELDEASNRLAHRLAGCGAGPGECVALLFE 1558
>UniRef50_A4KUB7 Cluster: TlmIV; n=3; root|Rep: TlmIV -
Streptoalloteichus hindustanus
Length = 2620
Score = 37.5 bits (83), Expect = 0.24
Identities = 18/48 (37%), Positives = 30/48 (62%)
Frame = +2
Query: 452 EIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
E A+ +PE A + GD +T+R+ S+R+A +R G K GE++A+
Sbjct: 1567 EAAQRFPEHTAVVDGDVRVTYRELAARSHRVARALRRLGAKPGELVAI 1614
>UniRef50_P39846 Cluster: Peptide synthetase 2; n=5; Bacillus|Rep:
Peptide synthetase 2 - Bacillus subtilis
Length = 2560
Score = 37.5 bits (83), Expect = 0.24
Identities = 20/76 (26%), Positives = 41/76 (53%)
Frame = +2
Query: 377 RVLLATMFRIWRWEKQGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYF 556
R+LL M + + + +++VS + + YPE A + G LT+R + + R A
Sbjct: 1484 RLLLEKMGQYAAYPRN-ENIVSLFEKQVAQYPEHIAVVCGHSQLTYRDLNEKAERAAAML 1542
Query: 557 KRQGFKSGEVIALFME 604
+QG ++G+++ L ++
Sbjct: 1543 IKQGVRTGDIVGLMLD 1558
Score = 33.9 bits (74), Expect = 3.0
Identities = 18/58 (31%), Positives = 32/58 (55%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
+++ + E A PE A MG+ T+RQ + +N+IA +G SG+++A+ M
Sbjct: 469 KTIPQLFEEQAHKTPEAAALKMGNECWTYRQLQVRANQIAHALIEKGVGSGDIVAVMM 526
>UniRef50_O68008 Cluster: Bacitracin synthetase 3 (BA3) [Includes:
ATP-dependent isoleucine adenylase (IleA) (Isoleucine
activase); ATP-dependent D-phenylalanine adenylase
(D-PheA) (D-phenylalanine activase); ATP-dependent
histidine adenylase (HisA) (Histidine activase);
ATP-dependent D-aspartate adenylase (D-AspA) (D-aspartate
activase); ATP-dependent asparagine adenylase (AsnA)
(Asparagine activase); Aspartate racemase (EC 5.1.1.13);
Phenylalanine racemase [ATP hydrolyzing] (EC 5.1.1.11)];
n=3; Bacillus|Rep: Bacitracin synthetase 3 (BA3)
[Includes: ATP-dependent isoleucine adenylase (IleA)
(Isoleucine activase); ATP-dependent D-phenylalanine
adenylase (D-PheA) (D-phenylalanine activase);
ATP-dependent histidine adenylase (HisA) (Histidine
activase); ATP-dependent D-aspartate adenylase (D-AspA)
(D-aspartate activase); ATP-dependent asparagine
adenylase (AsnA) (Asparagine activase); Aspartate
racemase (EC 5.1.1.13); Phenylalanine racemase [ATP
hydrolyzing] (EC 5.1.1.11)] - Bacillus licheniformis
Length = 6359
Score = 37.5 bits (83), Expect = 0.24
Identities = 15/59 (25%), Positives = 35/59 (59%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
+++ +AE A+ P+K A + D+ LT+RQ + SN++A + + +G + + + ++
Sbjct: 1496 KTICQLFAERAETSPDKTAVVFEDQTLTYRQLHERSNQLARFLREKGVQPDTAVGIMVD 1554
Score = 33.1 bits (72), Expect = 5.2
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +2
Query: 422 QGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
Q Q+V + + A PE+ A + D LT+R+ + +N++A + +G + + +A+ +
Sbjct: 4030 QDQTVHQLFEQQADKTPEQTAVVYADEKLTYRELNERANQLARLLRDKGADADQPVAIMI 4089
Query: 602 E 604
E
Sbjct: 4090 E 4090
>UniRef50_Q89CJ0 Cluster: Blr7807 protein; n=15; Proteobacteria|Rep:
Blr7807 protein - Bradyrhizobium japonicum
Length = 550
Score = 37.1 bits (82), Expect = 0.32
Identities = 20/51 (39%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +2
Query: 458 AKLYPEKKAFIMGD--RALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
A+ P K A+ M +A+T+R+ ++ SN+ A F+ G K+G+ IAL ME
Sbjct: 44 ARATPNKIAYQMAGTGKAITYRELDELSNQGAHLFRSLGLKAGDHIALLME 94
>UniRef50_Q0SEC4 Cluster: Possible long-chain-fatty-acid-CoA ligase;
n=8; Bacteria|Rep: Possible long-chain-fatty-acid-CoA
ligase - Rhodococcus sp. (strain RHA1)
Length = 507
Score = 37.1 bits (82), Expect = 0.32
Identities = 16/47 (34%), Positives = 28/47 (59%)
Frame = +2
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALF 598
A +P+++A DRA T+R+ +D +R A Y + G +GE +A +
Sbjct: 18 AAKFPDRRALTFEDRAWTYRELDDAVSRAAAYLRSLGLSAGERVAAY 64
>UniRef50_Q0S7M5 Cluster: AMP-binding CoA ligase; n=1; Rhodococcus
sp. RHA1|Rep: AMP-binding CoA ligase - Rhodococcus sp.
(strain RHA1)
Length = 536
Score = 37.1 bits (82), Expect = 0.32
Identities = 17/44 (38%), Positives = 27/44 (61%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
PE+ A I G R +T+R+ ED +NR+A +F G +G I + +
Sbjct: 17 PERVALICGARRVTYRELEDRANRLAHHFLEVGLTAGSHIGVHL 60
>UniRef50_A3Z2Q3 Cluster: Acyl-CoA synthase; n=1; Synechococcus sp.
WH 5701|Rep: Acyl-CoA synthase - Synechococcus sp. WH
5701
Length = 321
Score = 37.1 bits (82), Expect = 0.32
Identities = 16/49 (32%), Positives = 28/49 (57%)
Frame = +2
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
A+ YP+ A I D +T+R+ + +A Y + QG K G+ + L+M+
Sbjct: 32 ARRYPDHTAIIFYDAPITYRRLNEEVETLAGYLQAQGVKKGDRVLLYMQ 80
>UniRef50_A3PWM4 Cluster: AMP-dependent synthetase and ligase; n=3;
Mycobacterium|Rep: AMP-dependent synthetase and ligase -
Mycobacterium sp. (strain JLS)
Length = 515
Score = 37.1 bits (82), Expect = 0.32
Identities = 19/48 (39%), Positives = 33/48 (68%), Gaps = 2/48 (4%)
Frame = +2
Query: 467 YPEKKAFIM-GDR-ALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
+P++ A IM G R +LT+R+ ++ +NR+A YF+ G + + IA+F E
Sbjct: 10 HPDRPALIMAGSRESLTYREFDERANRVANYFRDLGLRRTDHIAIFAE 57
>UniRef50_Q1E7N4 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 1912
Score = 37.1 bits (82), Expect = 0.32
Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 5/82 (6%)
Frame = +2
Query: 374 LRVLLATMFRIWRWEKQGQSVVSR-----WAEIAKLYPEKKAFIMGDRALTFRQGEDFSN 538
+RV + +IW W + + + E A +PE+ A + D L++R+ ++FS
Sbjct: 195 IRVTNNELDKIWEWNETVPPTIDTCIHDIFIENASRHPERPAVVSWDGGLSYREVDEFST 254
Query: 539 RIAWYFKRQGFKSGEVIALFME 604
++A K GE I L E
Sbjct: 255 QLAMQLIDSNVKIGEPIMLCFE 276
>UniRef50_O68007 Cluster: Bacitracin synthetase 2 (BA2) [Includes:
ATP-dependent lysine adenylase (LysA) (Lysine activase);
ATP-dependent D-ornithine adenylase (D-OrnA)
(D-ornithine activase); Ornithine racemase (EC
5.1.1.12)]; n=4; Bacillus|Rep: Bacitracin synthetase 2
(BA2) [Includes: ATP-dependent lysine adenylase (LysA)
(Lysine activase); ATP-dependent D-ornithine adenylase
(D-OrnA) (D-ornithine activase); Ornithine racemase (EC
5.1.1.12)] - Bacillus licheniformis
Length = 2607
Score = 37.1 bits (82), Expect = 0.32
Identities = 15/51 (29%), Positives = 30/51 (58%)
Frame = +2
Query: 452 EIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
E A+ P+ A I D+ LT+R+ + +N++AW + +G K ++A+ +
Sbjct: 528 ERAEKTPDHTAVIFEDQQLTYRELNEKANQLAWLLREKGVKPDTIVAIMTD 578
>UniRef50_A1WPK7 Cluster: AMP-dependent synthetase and ligase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: AMP-dependent
synthetase and ligase - Verminephrobacter eiseniae
(strain EF01-2)
Length = 523
Score = 36.7 bits (81), Expect = 0.43
Identities = 17/45 (37%), Positives = 29/45 (64%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
P+ +A I G+R+LT+R+ +NR+A +G + G ++AL ME
Sbjct: 26 PDAQACIEGERSLTWRELNARANRVAQALHLRGVEHGHIVALSME 70
>UniRef50_A1SK93 Cluster: AMP-dependent synthetase and ligase; n=3;
Actinomycetales|Rep: AMP-dependent synthetase and ligase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 548
Score = 36.7 bits (81), Expect = 0.43
Identities = 15/43 (34%), Positives = 27/43 (62%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALF 598
P+ +A +GDR +T+ E +NR+A Y + QG G+ +A++
Sbjct: 17 PDNRALKVGDRVVTYADLEADANRLAHYLRAQGVGVGDHVAIY 59
>UniRef50_Q2GZD3 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 2471
Score = 36.7 bits (81), Expect = 0.43
Identities = 19/59 (32%), Positives = 30/59 (50%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
QS+ S A+ Y +K A I G LT+ Q SN A F R+G G+++ + ++
Sbjct: 32 QSIHSLLERTAEEYSDKTALICGHTTLTYGQLSSLSNHFARAFVRRGIGKGDLVGVALD 90
>UniRef50_Q7N1E2 Cluster: Similar to proteins involved in antibiotic
biosynthesis; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to proteins involved in antibiotic
biosynthesis - Photorhabdus luminescens subsp. laumondii
Length = 3270
Score = 36.3 bits (80), Expect = 0.56
Identities = 19/61 (31%), Positives = 32/61 (52%)
Frame = +2
Query: 422 QGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
+ Q + R A+ P+ A + GD+ LT+ Q +N++A Y QG K +IA+ +
Sbjct: 1588 RSQCIHERIEAFAEQTPDAIALVFGDQQLTYAQLNAKANQLAHYLVAQGAKPDSMIAICI 1647
Query: 602 E 604
E
Sbjct: 1648 E 1648
Score = 33.5 bits (73), Expect = 4.0
Identities = 15/59 (25%), Positives = 30/59 (50%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
Q+++ R+ K P++ A +T+R+ +N++A Y QG K + +F+E
Sbjct: 2662 QTLIDRFEAQVKATPDEIALNFAGETMTYRELNQRTNQLAQYLVNQGAKVNTPVVMFIE 2720
>UniRef50_Q4ZVI3 Cluster: Amino acid adenylation; n=3;
Pseudomonas|Rep: Amino acid adenylation - Pseudomonas
syringae pv. syringae (strain B728a)
Length = 3021
Score = 36.3 bits (80), Expect = 0.56
Identities = 17/56 (30%), Positives = 31/56 (55%)
Frame = +2
Query: 437 VSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
V R+ +A+ P+ A + +RALT+ + +NR+A Y QG + + + L +E
Sbjct: 1102 VKRFEAVAQRTPDAVALLADERALTYAELNQSANRLANYLIEQGVRPEQCVGLCLE 1157
>UniRef50_Q5KZW0 Cluster: Long-chain fatty-acid-CoA ligase; n=6;
Bacillaceae|Rep: Long-chain fatty-acid-CoA ligase -
Geobacillus kaustophilus
Length = 511
Score = 35.9 bits (79), Expect = 0.74
Identities = 18/51 (35%), Positives = 29/51 (56%)
Frame = +2
Query: 449 AEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
A A+ +PEK A I G+ +L++ + NR+A R G G+ +AL+M
Sbjct: 8 ARNARKFPEKTAVIEGESSLSYAEVNCMVNRLASSLARLGVGRGDKVALYM 58
>UniRef50_A0UXD2 Cluster: Amino acid adenylation domain; n=1;
Clostridium cellulolyticum H10|Rep: Amino acid
adenylation domain - Clostridium cellulolyticum H10
Length = 4196
Score = 35.9 bits (79), Expect = 0.74
Identities = 15/45 (33%), Positives = 24/45 (53%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
P A I + LT+ + + SNRIAWY +G + V+ + +E
Sbjct: 1318 PHNIALIFEGKQLTYHELNEKSNRIAWYLIEKGVREDSVVGIMVE 1362
>UniRef50_A2R3M8 Cluster: Catalytic activity: polyketide synthases
are multifunctional enzymes; n=1; Aspergillus niger|Rep:
Catalytic activity: polyketide synthases are
multifunctional enzymes - Aspergillus niger
Length = 1869
Score = 35.9 bits (79), Expect = 0.74
Identities = 19/62 (30%), Positives = 31/62 (50%)
Frame = +2
Query: 419 KQGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALF 598
K G +VVS + + Y K A + G+ LT+ S+R+A +G G V+AL
Sbjct: 30 KLGHNVVSLFDQTQTRYSPKAAIVCGEHTLTYGALASDSDRLACLLLSRGISRGHVVALA 89
Query: 599 ME 604
++
Sbjct: 90 LD 91
>UniRef50_A1DC00 Cluster: Nonribosomal peptide synthase, putative;
n=3; Pezizomycotina|Rep: Nonribosomal peptide synthase,
putative - Neosartorya fischeri (strain ATCC 1020 / DSM
3700 / NRRL 181)(Aspergillus fischerianus (strain ATCC
1020 / DSM 3700 / NRRL 181))
Length = 2229
Score = 35.9 bits (79), Expect = 0.74
Identities = 20/73 (27%), Positives = 34/73 (46%), Gaps = 5/73 (6%)
Frame = +2
Query: 401 RIWRW-----EKQGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQ 565
R+W W E+ V +++ YP K A D LT+ Q + S ++A + +
Sbjct: 80 RVWTWNVKVPEEVKGCVHDLFSQSVSQYPHKTAISAWDGELTYSQWDTLSTQLAHHLIQT 139
Query: 566 GFKSGEVIALFME 604
G + G+V+ L E
Sbjct: 140 GVRPGDVLPLIFE 152
>UniRef50_O30408 Cluster: Tyrocidine synthetase 2 (Tyrocidine
synthetase II) [Includes: ATP- dependent proline
adenylase (ProA) (Proline activase); ATP-dependent
phenylalanine adenylase (PheA) (Phenylalanine activase);
ATP-dependent D-phenylalanine adenylase (D-PheA)
(D-phenylalanine activase); Phenylalanine racemase
[ATP-hydrolyzing] (EC 5.1.1.11)]; n=5;
Paenibacillaceae|Rep: Tyrocidine synthetase 2
(Tyrocidine synthetase II) [Includes: ATP- dependent
proline adenylase (ProA) (Proline activase);
ATP-dependent phenylalanine adenylase (PheA)
(Phenylalanine activase); ATP-dependent D-phenylalanine
adenylase (D-PheA) (D-phenylalanine activase);
Phenylalanine racemase [ATP-hydrolyzing] (EC 5.1.1.11)]
- Brevibacillus parabrevis
Length = 3587
Score = 35.9 bits (79), Expect = 0.74
Identities = 13/49 (26%), Positives = 32/49 (65%)
Frame = +2
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
A+ PE+ A + D+ LT+R+ ++ SN++A + +++G +G ++ ++
Sbjct: 477 AEKTPEQVAVVFADQHLTYRELDEKSNQLARFLRKKGIGTGSLVGTLLD 525
>UniRef50_Q93I56 Cluster: Iturin A synthetase A; n=6; Bacillus|Rep:
Iturin A synthetase A - Bacillus subtilis
Length = 3982
Score = 35.5 bits (78), Expect = 0.98
Identities = 17/57 (29%), Positives = 34/57 (59%), Gaps = 1/57 (1%)
Frame = +2
Query: 428 QSVVSRWAEI-AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
+ V RW E+ A+ P+ +A I G+ T+RQ + +NR+A + +G ++ + +A+
Sbjct: 2950 KETVYRWFEMQAEQSPDHEAVIFGNERYTYRQLNERANRLARTLRTKGVQADQFVAI 3006
>UniRef50_Q5DIP4 Cluster: PvdJ; n=19; root|Rep: PvdJ - Pseudomonas
aeruginosa
Length = 4991
Score = 35.5 bits (78), Expect = 0.98
Identities = 16/60 (26%), Positives = 31/60 (51%)
Frame = +2
Query: 425 GQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
GQ V + A L P+ A + G+ L++ + +NR+AW + +G S ++ + +E
Sbjct: 511 GQGVHRLFEAQAGLTPDAPALLFGEERLSYAELNALANRLAWRLREEGVGSDVLVGIALE 570
>UniRef50_A6FHU7 Cluster: O-succinylbenzoic acid--CoA ligase; n=1;
Moritella sp. PE36|Rep: O-succinylbenzoic acid--CoA
ligase - Moritella sp. PE36
Length = 483
Score = 35.5 bits (78), Expect = 0.98
Identities = 18/49 (36%), Positives = 24/49 (48%)
Frame = +2
Query: 446 WAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIA 592
W A L PEK A + G++ T++Q N A QG + G VIA
Sbjct: 12 WQHWADLTPEKVALVYGEQQFTWQQVNGLVNGYAKQLSGQGVREGNVIA 60
>UniRef50_A3P7D6 Cluster: Non-ribosomal peptide synthase; n=34;
Bacteria|Rep: Non-ribosomal peptide synthase -
Burkholderia pseudomallei (strain 1106a)
Length = 4468
Score = 35.5 bits (78), Expect = 0.98
Identities = 15/43 (34%), Positives = 27/43 (62%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALF 598
P+ A I +RALT+ + +NR+A Y + +G + G+ +AL+
Sbjct: 560 PDAIAVIQDERALTYAELNRCANRLAHYLRARGVRGGDRVALY 602
>UniRef50_A0QH53 Cluster: Linear gramicidin synthetase subunit D; n=4;
Bacteria|Rep: Linear gramicidin synthetase subunit D -
Mycobacterium avium (strain 104)
Length = 10421
Score = 35.5 bits (78), Expect = 0.98
Identities = 17/55 (30%), Positives = 32/55 (58%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
S+ + +AE A P+ A + G R +T+R+ ++ +NR+A + +G G +AL
Sbjct: 5532 SLPTLFAEQAARTPDAVALVCGGRRMTYRELDEAANRVAHLLRVRGAGPGHTVAL 5586
Score = 34.3 bits (75), Expect = 2.3
Identities = 18/55 (32%), Positives = 31/55 (56%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
SV +R+A A P+ A R++T+R+ ++ +NR+A + G GE +AL
Sbjct: 3424 SVPTRFAAQAARTPDAVALTCDGRSMTYRELDEAANRLAHFMIHHGAGPGERVAL 3478
Score = 34.3 bits (75), Expect = 2.3
Identities = 19/58 (32%), Positives = 33/58 (56%)
Frame = +2
Query: 422 QGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
Q S+ + +AE A P+ A + DR+ T+R+ ++ +NR+A G +GE +AL
Sbjct: 8074 QFHSIPTVFAEQAARTPDAVALVYEDRSWTYRELDEAANRLAHRLAGFGVGAGERVAL 8131
Score = 32.7 bits (71), Expect = 6.9
Identities = 16/48 (33%), Positives = 29/48 (60%)
Frame = +2
Query: 452 EIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
++A++ PE A + D ++T+RQ ++ SNR+A G G+ +AL
Sbjct: 4487 QVARV-PETVALVCDDLSVTYRQLDEASNRLAHRLAAAGAGPGQTVAL 4533
>UniRef50_Q93H58 Cluster: Non-ribosomal peptide synthetase; n=1;
Streptomyces avermitilis|Rep: Non-ribosomal peptide
synthetase - Streptomyces avermitilis
Length = 3686
Score = 35.1 bits (77), Expect = 1.3
Identities = 17/64 (26%), Positives = 36/64 (56%)
Frame = +2
Query: 413 WEKQGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIA 592
+E + SV+ R+ E A P A +G+R LT+ + ++ +NR+A + +G + +A
Sbjct: 2568 YEAETASVLRRFEEQAARTPRAPAVTLGERTLTYAELDEHANRLAHALRARGVGAESRVA 2627
Query: 593 LFME 604
+ ++
Sbjct: 2628 VQLD 2631
>UniRef50_Q7N2F7 Cluster: Complete genome; segment 11/17; n=4;
Photorhabdus luminescens subsp. laumondii|Rep: Complete
genome; segment 11/17 - Photorhabdus luminescens subsp.
laumondii
Length = 5457
Score = 35.1 bits (77), Expect = 1.3
Identities = 15/45 (33%), Positives = 26/45 (57%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
PE A I GD+ L++ + +NR+A+ QG + + +AL +E
Sbjct: 3526 PEATALIAGDKTLSYMELNTCANRLAYQLIEQGIRPDDHVALLLE 3570
>UniRef50_Q3KE51 Cluster: Amino acid adenylation; n=7;
Pseudomonas|Rep: Amino acid adenylation - Pseudomonas
fluorescens (strain PfO-1)
Length = 5422
Score = 35.1 bits (77), Expect = 1.3
Identities = 21/75 (28%), Positives = 37/75 (49%)
Frame = +2
Query: 377 RVLLATMFRIWRWEKQGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYF 556
R LL R G +V + KL+P+ A + G+ ALT+ + +NR+A +
Sbjct: 1607 RELLVGFNATQREYPSGSTVHGLFELQVKLHPQAVAAVHGNAALTYDELNQRANRLAHFL 1666
Query: 557 KRQGFKSGEVIALFM 601
QG + G+ +A+ +
Sbjct: 1667 IGQGVQPGDPVAILL 1681
>UniRef50_A6V024 Cluster: Amino acid adenylation domain; n=1;
Pseudomonas aeruginosa PA7|Rep: Amino acid adenylation
domain - Pseudomonas aeruginosa PA7
Length = 992
Score = 35.1 bits (77), Expect = 1.3
Identities = 18/58 (31%), Positives = 34/58 (58%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
SV+ +++ AK +PE+ A + R+LT+R+ + S+R+A +G G ++ L E
Sbjct: 5 SVLGLFSQQAKSHPERLAIVDHARSLTYRELDRLSDRLAARLAGRGVGKGALLPLLAE 62
>UniRef50_A1E027 Cluster: Ibuprofen CoA ligase; n=2; cellular
organisms|Rep: Ibuprofen CoA ligase - Sphingomonas sp.
Ibu-2
Length = 527
Score = 35.1 bits (77), Expect = 1.3
Identities = 14/49 (28%), Positives = 30/49 (61%)
Frame = +2
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
A+ YP K A++ G+R+ ++R+ + S+R ++ G + GE +A+ +
Sbjct: 11 ARNYPTKTAYLCGERSRSWREMDQRSDRFGVALQQLGHRPGEAVAILTQ 59
>UniRef50_UPI000023DA7C Cluster: hypothetical protein FG11395.1; n=1;
Gibberella zeae PH-1|Rep: hypothetical protein FG11395.1
- Gibberella zeae PH-1
Length = 2381
Score = 34.7 bits (76), Expect = 1.7
Identities = 18/57 (31%), Positives = 30/57 (52%)
Frame = +2
Query: 434 VVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
V R +++K P+ A D LT++Q ED+SN A + QG G+ + + +E
Sbjct: 1301 VHDRIRDLSKSQPDALAVHSMDLDLTYQQVEDYSNHFASHLISQGVTQGDFVPVLIE 1357
>UniRef50_Q4ANX0 Cluster: O-succinylbenzoate-CoA ligase; n=2;
Chlorobiaceae|Rep: O-succinylbenzoate-CoA ligase -
Chlorobium phaeobacteroides BS1
Length = 482
Score = 34.7 bits (76), Expect = 1.7
Identities = 17/51 (33%), Positives = 26/51 (50%)
Frame = +2
Query: 449 AEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
A AK + + A + G L+F E + RIA + G + G+V+AL M
Sbjct: 5 AAAAKTFSDSPALVTGKEILSFHDLEATTTRIAHTLSQHGIRKGDVVALCM 55
>UniRef50_Q1D6A2 Cluster: Non-ribosomal peptide synthase; n=1;
Myxococcus xanthus DK 1622|Rep: Non-ribosomal peptide
synthase - Myxococcus xanthus (strain DK 1622)
Length = 5741
Score = 34.7 bits (76), Expect = 1.7
Identities = 15/49 (30%), Positives = 26/49 (53%)
Frame = +2
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
A+ P+ A + GD LT+R+ +N +AW + QG ++ LF +
Sbjct: 1174 AQRTPDAVAVVCGDGVLTYRELNQRANAVAWRLREQGVGPECIVGLFAD 1222
>UniRef50_Q06YY9 Cluster: Nonribosomal peptide synthetase; n=1;
Streptomyces fungicidicus|Rep: Nonribosomal peptide
synthetase - Streptomyces fungicidicus
Length = 859
Score = 34.7 bits (76), Expect = 1.7
Identities = 16/53 (30%), Positives = 32/53 (60%)
Frame = +2
Query: 446 WAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
+AE A P+ A + GDR +T+R+ +++S+R+A + G G ++ + +E
Sbjct: 283 FAERAAERPDALALVDGDRTVTYRRLDEWSDRLAHGLRAAGAGDGTLVGVCLE 335
>UniRef50_A1SPU7 Cluster: AMP-dependent synthetase and ligase; n=11;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 521
Score = 34.7 bits (76), Expect = 1.7
Identities = 13/46 (28%), Positives = 28/46 (60%)
Frame = +2
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
A +P++ A ++GD L++ + + F+N +A +G + G+ +AL
Sbjct: 14 AATHPDRTAIVLGDTRLSYAEVDTFANMVANLLVSRGIRPGDKVAL 59
>UniRef50_Q08Y42 Cluster: AMP-dependent synthetase and ligase; n=3;
Proteobacteria|Rep: AMP-dependent synthetase and ligase
- Stigmatella aurantiaca DW4/3-1
Length = 845
Score = 34.3 bits (75), Expect = 2.3
Identities = 13/46 (28%), Positives = 29/46 (63%)
Frame = +2
Query: 467 YPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
+P+KKA ++G ++ T+ Q + ++R+A +G G+ +A++ E
Sbjct: 15 FPDKKAIVLGAQSATYAQLDRMASRVAHALVDRGIVRGDRVAIYSE 60
>UniRef50_A4STS1 Cluster: Non-ribosomal peptide synthetase module;
n=3; Gammaproteobacteria|Rep: Non-ribosomal peptide
synthetase module - Aeromonas salmonicida (strain A449)
Length = 1459
Score = 34.3 bits (75), Expect = 2.3
Identities = 16/41 (39%), Positives = 26/41 (63%)
Frame = +2
Query: 473 EKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
+K A I GDR +++R D RI F+R+G +G+V+A+
Sbjct: 883 DKIALIQGDRRISYRTLGDSVLRIMGAFEREGITAGKVVAI 923
>UniRef50_A3RXA3 Cluster: AMP-(Fatty)acid ligases; n=6;
Burkholderiales|Rep: AMP-(Fatty)acid ligases - Ralstonia
solanacearum UW551
Length = 563
Score = 34.3 bits (75), Expect = 2.3
Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 1/61 (1%)
Frame = +2
Query: 425 GQSVVSRW-AEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
G+ + R+ A A PE+ A + R + +R+ + S R+A F+R G G+ +ALF+
Sbjct: 14 GEMPLHRYCAHHAAQTPERIALLWYGRTICWRELDQLSTRLAVQFQRLGVARGDRVALFL 73
Query: 602 E 604
+
Sbjct: 74 Q 74
>UniRef50_Q8YTS1 Cluster: Multifunctional peptide synthetase; n=3;
Cyanobacteria|Rep: Multifunctional peptide synthetase -
Anabaena sp. (strain PCC 7120)
Length = 1164
Score = 33.9 bits (74), Expect = 3.0
Identities = 16/52 (30%), Positives = 32/52 (61%)
Frame = +2
Query: 449 AEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
A++ K P++ A I +++LT+ + SN++A Y K++G K ++ L +E
Sbjct: 541 AQVEKT-PDEVAIIFENQSLTYTELNQKSNQVAHYLKKKGVKPEVIVGLCVE 591
>UniRef50_Q4C3C0 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation:Thioester reductase; n=1; Crocosphaera
watsonii WH 8501|Rep: Non-ribosomal peptide
synthase:Amino acid adenylation:Thioester reductase -
Crocosphaera watsonii
Length = 1993
Score = 33.9 bits (74), Expect = 3.0
Identities = 15/59 (25%), Positives = 32/59 (54%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
Q + + E K P+K A + ++ LT+ + +N++A Y + QG K ++ +++E
Sbjct: 457 QCIHKLFEEQVKRKPDKVAVVFEEQQLTYNELNVKANQLANYLQNQGIKPDSLVGVYLE 515
>UniRef50_A6V359 Cluster: Linear gramicidin synthetase subunit C;
n=4; Proteobacteria|Rep: Linear gramicidin synthetase
subunit C - Pseudomonas aeruginosa PA7
Length = 528
Score = 33.9 bits (74), Expect = 3.0
Identities = 17/52 (32%), Positives = 30/52 (57%)
Frame = +2
Query: 446 WAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
+A IA P+ A +R L++ Q +NR+AW +G ++G+VIA+ +
Sbjct: 34 FARIAAERPQAIALRYRERELSYAQLNAQANRLAWQLLARGVQTGDVIAVVL 85
>UniRef50_A5A9U3 Cluster: Mps2 protein; n=2; Mycobacterium|Rep: Mps2
protein - Mycobacterium abscessus
Length = 2581
Score = 33.9 bits (74), Expect = 3.0
Identities = 16/44 (36%), Positives = 24/44 (54%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
PE A + DR+ T+R+ + +NRIA G GEV+ L +
Sbjct: 54 PETVALVCRDRSWTYRELDQITNRIAHLLAGNGAGPGEVVGLLV 97
>UniRef50_Q9NS00 Cluster: Glycoprotein-N-acetylgalactosamine
3-beta-galactosyltransferase 1; n=25; Euteleostomi|Rep:
Glycoprotein-N-acetylgalactosamine
3-beta-galactosyltransferase 1 - Homo sapiens (Human)
Length = 363
Score = 33.9 bits (74), Expect = 3.0
Identities = 17/55 (30%), Positives = 29/55 (52%)
Frame = +1
Query: 358 EGFSRSKGTVSDNVQDMALGKTRPVSGVKVGGNSEAVSGKEGFYHGGQGSHLSSG 522
+ F K T S +++D+ALG+ + V+ G + + + GKE F+ HL G
Sbjct: 225 DAFKTDKCTHSSSIEDLALGRCMEIMNVEAGDSRDTI-GKETFHPFVPEHHLIKG 278
>UniRef50_Q7N848 Cluster: Similarities with peptide synthetase like
pristinamycin I synthase 3; n=3; Photorhabdus
luminescens subsp. laumondii|Rep: Similarities with
peptide synthetase like pristinamycin I synthase 3 -
Photorhabdus luminescens subsp. laumondii
Length = 2009
Score = 33.5 bits (73), Expect = 4.0
Identities = 16/58 (27%), Positives = 30/58 (51%)
Frame = +2
Query: 422 QGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
QG+ + E L PEK A + G+ L+++ +N++A Y QG + ++A+
Sbjct: 545 QGRCFHELFEEQVALNPEKTALVFGEETLSYQAVNVQANQLAHYLIEQGIQPDTLVAI 602
>UniRef50_Q6LGA3 Cluster: Hypothetical peptide synthetase; n=1;
Photobacterium profundum|Rep: Hypothetical peptide
synthetase - Photobacterium profundum (Photobacterium
sp. (strain SS9))
Length = 2168
Score = 33.5 bits (73), Expect = 4.0
Identities = 14/43 (32%), Positives = 28/43 (65%)
Frame = +2
Query: 467 YPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
+PEK+A I G ++LT+ + E +NR+A + +G +S ++ +
Sbjct: 527 HPEKQAVIHGGQSLTYAELESRANRLANWLIERGLRSESLVGI 569
>UniRef50_Q84BC7 Cluster: NcpB; n=3; Cyanobacteria|Rep: NcpB -
Nostoc sp. ATCC 53789
Length = 4803
Score = 33.5 bits (73), Expect = 4.0
Identities = 16/61 (26%), Positives = 34/61 (55%)
Frame = +2
Query: 422 QGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
Q +S+ + E +L P+ A + ++ LT+R+ +N++A Y K G K+ ++ + +
Sbjct: 479 QDKSIHQLFEEQVELTPDAVAVVYENQHLTYRELNSRANQLAHYLKSLGVKADALVGICV 538
Query: 602 E 604
E
Sbjct: 539 E 539
>UniRef50_Q333V2 Cluster: NRPS protein; n=1; Micromonospora sp.
ML1|Rep: NRPS protein - Micromonospora sp. ML1
Length = 768
Score = 33.5 bits (73), Expect = 4.0
Identities = 18/53 (33%), Positives = 30/53 (56%), Gaps = 1/53 (1%)
Frame = +2
Query: 449 AEIAKLYPEKKAFIMGDR-ALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
AE A+ +P++ A + D+ LT R+ +NR+A + G G+ +ALF E
Sbjct: 24 AEAAERHPDRPAIVTSDKQVLTHRELHRRANRLARLLRDLGVGRGDTVALFGE 76
>UniRef50_Q2ANW8 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=1; Bacillus weihenstephanensis KBAB4|Rep:
Non-ribosomal peptide synthase:Amino acid adenylation -
Bacillus weihenstephanensis KBAB4
Length = 4080
Score = 33.5 bits (73), Expect = 4.0
Identities = 13/45 (28%), Positives = 25/45 (55%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
P+ A + +R +T+ + D SN ++ R+G K GE+I + +
Sbjct: 477 PDNVAIVYKNRTMTYEELNDISNNLSNELLRKGVKKGEIIGIMTD 521
>UniRef50_Q18ZS3 Cluster: AMP-dependent synthetase and ligase; n=5;
Firmicutes|Rep: AMP-dependent synthetase and ligase -
Desulfitobacterium hafniense (strain DCB-2)
Length = 539
Score = 33.5 bits (73), Expect = 4.0
Identities = 20/65 (30%), Positives = 36/65 (55%)
Frame = +2
Query: 401 RIWRWEKQGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSG 580
++W G+++ S W+E Y + A DR +T+R+ E + R+A ++R+GF G
Sbjct: 16 KVWEDITLGKAL-SAWSET---YGDNIALTEADRQVTYRELETAARRMAAGWQRRGFGRG 71
Query: 581 EVIAL 595
+ I L
Sbjct: 72 DKIVL 76
>UniRef50_A3KI35 Cluster: Putative peptide synthetase; n=1;
Streptomyces ambofaciens ATCC 23877|Rep: Putative
peptide synthetase - Streptomyces ambofaciens ATCC 23877
Length = 2873
Score = 33.5 bits (73), Expect = 4.0
Identities = 18/59 (30%), Positives = 30/59 (50%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
+++ + E A PE+ A GD LT+ + +NR+A +G G V+AL +E
Sbjct: 456 RTLTELFEERAAAGPERSAVTCGDERLTYAELNAEANRLARLLAERGAGPGRVVALALE 514
>UniRef50_A4QTM3 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 631
Score = 33.5 bits (73), Expect = 4.0
Identities = 16/50 (32%), Positives = 29/50 (58%)
Frame = +2
Query: 452 EIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
++ + P +A + +LT++Q D +NR A +F QG + + +ALFM
Sbjct: 60 DVVRQKPNAEAIWTREGSLTWQQLYDGTNRFAQWFLAQGVRPKDFVALFM 109
>UniRef50_P27743 Cluster:
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine
synthase (EC 6.3.2.26)
(Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine
synthetase); n=5; Actinomycetales|Rep:
N-(5-amino-5-carboxypentanoyl)-L-cysteinyl-D-valine
synthase (EC 6.3.2.26)
(Delta-(L-alpha-aminoadipyl)-L-cysteinyl-D-valine
synthetase) - Nocardia lactamdurans
Length = 3649
Score = 33.5 bits (73), Expect = 4.0
Identities = 16/52 (30%), Positives = 33/52 (63%), Gaps = 1/52 (1%)
Frame = +2
Query: 452 EIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGF-KSGEVIALFME 604
E+A +P++ A + GD LT+R+ + +NR+A + + ++ E+IAL ++
Sbjct: 2407 EVAATWPDRVAVVHGDVRLTYRELNERANRLAHHLRSVAEPRADELIALVLD 2458
>UniRef50_UPI000023F703 Cluster: hypothetical protein FG00042.1; n=1;
Gibberella zeae PH-1|Rep: hypothetical protein FG00042.1
- Gibberella zeae PH-1
Length = 7791
Score = 33.1 bits (72), Expect = 5.2
Identities = 16/49 (32%), Positives = 24/49 (48%)
Frame = +2
Query: 443 RWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVI 589
R +A P+ +A D TF++ SNR A Y + QG K G ++
Sbjct: 3489 RLDRLAVSNPDAEAVCAWDGIFTFKELNSLSNRYAVYLQSQGIKPGNIV 3537
>UniRef50_Q2SAB9 Cluster: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II; n=4;
Gammaproteobacteria|Rep: Acyl-CoA synthetases
(AMP-forming)/AMP-acid ligases II - Hahella chejuensis
(strain KCTC 2396)
Length = 611
Score = 33.1 bits (72), Expect = 5.2
Identities = 15/49 (30%), Positives = 28/49 (57%)
Frame = +2
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
A + + A + DR ++++ ++NR A YF+ +G G+VIA +E
Sbjct: 52 ANAHGDCDAVLYRDRRISYQAFNAWANRFAHYFRARGIARGDVIAFNLE 100
>UniRef50_O31782 Cluster: Polyketide synthase of type I; n=2;
Bacillus subtilis|Rep: Polyketide synthase of type I -
Bacillus subtilis
Length = 5488
Score = 33.1 bits (72), Expect = 5.2
Identities = 15/51 (29%), Positives = 29/51 (56%)
Frame = +2
Query: 452 EIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
E AK P+ A + DR+LT+++ ++ S +A Y + QG + + + + E
Sbjct: 474 EKAKQTPDAVAVMFEDRSLTYKEVDEKSTSVAVYLQHQGVRPEQPVGICAE 524
>UniRef50_Q4PK62 Cluster: Predicted very-long-chain acyl-CoA
synthetase; n=1; uncultured bacterium MedeBAC49C08|Rep:
Predicted very-long-chain acyl-CoA synthetase -
uncultured bacterium MedeBAC49C08
Length = 588
Score = 33.1 bits (72), Expect = 5.2
Identities = 14/48 (29%), Positives = 24/48 (50%)
Frame = +2
Query: 461 KLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
K YP + AF+ + LT++Q D + + + G G+ AL M+
Sbjct: 46 KKYPNENAFLFKEEVLTWKQASDKIDNYSGVIRSLGLNKGDSFALLMD 93
>UniRef50_Q4C639 Cluster: Amino acid adenylation; n=1; Crocosphaera
watsonii WH 8501|Rep: Amino acid adenylation -
Crocosphaera watsonii
Length = 2281
Score = 33.1 bits (72), Expect = 5.2
Identities = 19/59 (32%), Positives = 29/59 (49%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
QS+ SR+ E K YP+K A D T+++ +N+IA G +ALF +
Sbjct: 1506 QSIPSRFEEQVKKYPDKIAVQSKDNQYTYQKLNTEANKIAKSLLNLGIDKQAKVALFFD 1564
>UniRef50_Q2VQ12 Cluster: Nonribosomal peptide synthetase F; n=1;
Brevibacillus texasporus|Rep: Nonribosomal peptide
synthetase F - Brevibacillus texasporus
Length = 2491
Score = 33.1 bits (72), Expect = 5.2
Identities = 11/45 (24%), Positives = 27/45 (60%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
PE+ A + + T+R+ + +N++AW +++ + E++A+ E
Sbjct: 483 PEQIAVVFKGESFTYRELNEKANQLAWVLRKREVRPNEIVAIMAE 527
>UniRef50_Q091C0 Cluster: Non-ribosomal peptide synthase; n=2;
Cystobacterineae|Rep: Non-ribosomal peptide synthase -
Stigmatella aurantiaca DW4/3-1
Length = 1443
Score = 33.1 bits (72), Expect = 5.2
Identities = 17/66 (25%), Positives = 33/66 (50%)
Frame = +2
Query: 407 WRWEKQGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEV 586
W+ + +G + A P+ A +MGD LT+ + + S+R+A Y + G V
Sbjct: 523 WKDDARGHCLHELIEAQALQAPDACAIVMGDWELTYGELDQLSDRLAVYLQSLGVGPEGV 582
Query: 587 IALFME 604
+ +++E
Sbjct: 583 VGIYLE 588
>UniRef50_O87314 Cluster: FxbC; n=5; Mycobacterium smegmatis|Rep: FxbC
- Mycobacterium smegmatis
Length = 4976
Score = 33.1 bits (72), Expect = 5.2
Identities = 16/57 (28%), Positives = 32/57 (56%)
Frame = +2
Query: 425 GQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
G+++ + +AE+A YP+ A GD LT+R+ +D + +A +G + +A+
Sbjct: 1573 GRTLGASFAEVAATYPDAVAVSCGDTRLTYRELDDRAAAVAATLAERGVGAESRVAI 1629
>UniRef50_A6P629 Cluster: Nonribosomal peptide synthetase; n=1;
Microcystis aeruginosa|Rep: Nonribosomal peptide
synthetase - Microcystis aeruginosa
Length = 1619
Score = 33.1 bits (72), Expect = 5.2
Identities = 16/49 (32%), Positives = 27/49 (55%)
Frame = +2
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
AK+ P++ A + D +LT+ Q SNR+A + G + E + L +E
Sbjct: 473 AKINPQEIALVFEDESLTYDQLNLLSNRLAHHLHNLGLQPDERVGLCLE 521
>UniRef50_A5YBV1 Cluster: Fusaricidin synthetase; n=1; Paenibacillus
polymyxa|Rep: Fusaricidin synthetase - Paenibacillus
polymyxa (Bacillus polymyxa)
Length = 2564
Score = 33.1 bits (72), Expect = 5.2
Identities = 17/50 (34%), Positives = 29/50 (58%)
Frame = +2
Query: 446 WAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
+AE K PE+ A + GD LT+ + ED ++R+A +R G + +A+
Sbjct: 1506 FAEQVKRTPEQTALVFGDVQLTYLELEDKASRLAQTLRRLGTLREQPVAV 1555
>UniRef50_A3HJ78 Cluster: Amino acid adenylation domain; n=1;
Pseudomonas putida GB-1|Rep: Amino acid adenylation
domain - Pseudomonas putida (strain GB-1)
Length = 3942
Score = 33.1 bits (72), Expect = 5.2
Identities = 16/52 (30%), Positives = 29/52 (55%)
Frame = +2
Query: 449 AEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
AE A+L P+ A + GD+ L++ Q + +NR+A + G K + + +E
Sbjct: 3101 AEHARLRPDALAVVCGDQQLSYAQLDQRANRLAHHLIALGTKPESTVGIALE 3152
>UniRef50_A1RCH2 Cluster: Putative coenzyme A ligase; n=1;
Arthrobacter aurescens TC1|Rep: Putative coenzyme A
ligase - Arthrobacter aurescens (strain TC1)
Length = 547
Score = 33.1 bits (72), Expect = 5.2
Identities = 16/53 (30%), Positives = 31/53 (58%)
Frame = +2
Query: 449 AEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFMET 607
A+ A+ P K +GD +LT+++ D + A F+R+G +G+ + L M++
Sbjct: 22 ADQARRRPSKAFLRVGDVSLTYQEAHDRVDSFAAGFQRRGVHAGDRVLLVMDS 74
>UniRef50_Q5D6D3 Cluster: Nonribosomal peptide synthetase 6; n=5;
Pleosporales|Rep: Nonribosomal peptide synthetase 6 -
Cochliobolus heterostrophus (Drechslera maydis)
Length = 1761
Score = 33.1 bits (72), Expect = 5.2
Identities = 18/52 (34%), Positives = 28/52 (53%)
Frame = +2
Query: 449 AEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
+E A L+PEK A D LT+ Q ED+S+++A + S +I + E
Sbjct: 62 SERAALHPEKIAIDAWDGTLTYGQIEDYSDKLAKLLRLLDDSSNRIIPVLFE 113
>UniRef50_UPI0000E488E2 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 514
Score = 32.7 bits (71), Expect = 6.9
Identities = 17/57 (29%), Positives = 28/57 (49%)
Frame = +2
Query: 431 SVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
++ ++ E A P K I + T+ +NRIA +R GFK G+ +A F+
Sbjct: 36 TIADKFEEHATKSPAKTMLIFEGKKYTYDDVNRRANRIARIAQRMGFKRGDKVAFFI 92
>UniRef50_Q4ZV19 Cluster: Non-ribosomal peptide synthase:Amino acid
adenylation; n=6; Pseudomonadaceae|Rep: Non-ribosomal
peptide synthase:Amino acid adenylation - Pseudomonas
syringae pv. syringae (strain B728a)
Length = 2883
Score = 32.7 bits (71), Expect = 6.9
Identities = 18/56 (32%), Positives = 28/56 (50%)
Frame = +2
Query: 437 VSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
+S W + + K A +G + L+F + E SNR A Y Q K G +AL ++
Sbjct: 505 LSLWQQGLRAGRGKTALRVGQQVLSFDELETRSNRFARYLHAQDIKPGMTVALCLD 560
>UniRef50_Q140M1 Cluster: Putative long chain fatty acid CoA ligase;
n=1; Burkholderia xenovorans LB400|Rep: Putative long
chain fatty acid CoA ligase - Burkholderia xenovorans
(strain LB400)
Length = 543
Score = 32.7 bits (71), Expect = 6.9
Identities = 12/50 (24%), Positives = 31/50 (62%)
Frame = +2
Query: 452 EIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
E A+ +PE+ ++ + ++++Q ++ +R+A G + G+V+A++M
Sbjct: 24 EAARKWPERTGWVFEEEHISYQQMKEHVDRVARALLASGIERGDVVAVWM 73
>UniRef50_Q0SEL8 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 513
Score = 32.7 bits (71), Expect = 6.9
Identities = 14/42 (33%), Positives = 25/42 (59%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
P + A ++GDRALT+R+ + S +A G + G+V+ +
Sbjct: 12 PGRIAIVVGDRALTYRELDSASEALARQLAAVGVRPGQVVLI 53
>UniRef50_O07944 Cluster: Pristinamycin I synthase 3 and 4; n=2;
Streptomyces|Rep: Pristinamycin I synthase 3 and 4 -
Streptomyces pristinaespiralis
Length = 4848
Score = 32.7 bits (71), Expect = 6.9
Identities = 15/56 (26%), Positives = 33/56 (58%)
Frame = +2
Query: 428 QSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
+++ + + + A P+ A +MGDR+LT+ + + +NR+A + G +++AL
Sbjct: 1517 RTLTALFEQQAAATPDATALVMGDRSLTYAELDARANRLARHLVALGAGPEQIVAL 1572
>UniRef50_A3Y827 Cluster: 2,3-dihydroxybenzoate--[carrier protein]
ligase; n=1; Marinomonas sp. MED121|Rep:
2,3-dihydroxybenzoate--[carrier protein] ligase -
Marinomonas sp. MED121
Length = 453
Score = 32.7 bits (71), Expect = 6.9
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = +2
Query: 452 EIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFK 574
E A+ K A I GDR +T+ E +N +A Y ++QG K
Sbjct: 33 EQAEANAHKVAIIEGDRQITYLALEQMANNLALYLQQQGVK 73
>UniRef50_Q6C6T2 Cluster: Similar to sp|P34244 Saccharomyces
cerevisiae YKL101w HSL1 ser/thr protein kinase; n=1;
Yarrowia lipolytica|Rep: Similar to sp|P34244
Saccharomyces cerevisiae YKL101w HSL1 ser/thr protein
kinase - Yarrowia lipolytica (Candida lipolytica)
Length = 1058
Score = 32.7 bits (71), Expect = 6.9
Identities = 12/32 (37%), Positives = 19/32 (59%)
Frame = -2
Query: 273 MVGEPRRSHPSPAVVSAMDVRIIPLHRSASSN 178
+V PRR P+P V S D ++P+H+ +N
Sbjct: 809 VVSAPRRPAPAPPVQSVADTMVLPMHQQQQNN 840
>UniRef50_A1DJT7 Cluster: Polyketide synthase, putative; n=2;
Trichocomaceae|Rep: Polyketide synthase, putative -
Neosartorya fischeri (strain ATCC 1020 / DSM 3700 / NRRL
181)(Aspergillus fischerianus (strain ATCC 1020 / DSM
3700 / NRRL 181))
Length = 739
Score = 32.7 bits (71), Expect = 6.9
Identities = 15/45 (33%), Positives = 25/45 (55%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
P+ A D +LT+++ +D S R+A R+G G V+ L+ E
Sbjct: 233 PDSPAVCAWDGSLTYKELDDLSTRLALGLARKGVGRGVVVPLYFE 277
>UniRef50_A1CMH4 Cluster: AMP dependent ligase; n=7;
Trichocomaceae|Rep: AMP dependent ligase - Aspergillus
clavatus
Length = 632
Score = 32.7 bits (71), Expect = 6.9
Identities = 21/92 (22%), Positives = 45/92 (48%), Gaps = 2/92 (2%)
Frame = +2
Query: 335 YLWKKTH-KRDFLGLRVLLATMFRIWRWEKQGQ-SVVSRWAEIAKLYPEKKAFIMGDRAL 508
YL K H +D LR+ ++ QG+ +V + + K YP+ ++
Sbjct: 19 YLNAKFHIAKDISSLRLARKSIRSYEHAAAQGRGNVWFIFLQTVKKYPDMVCLWTREKVY 78
Query: 509 TFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
T+R ++ + + A +F +G K G+++A +++
Sbjct: 79 TYRDVQNLACQYAHFFLAKGVKKGDLVAFYLQ 110
>UniRef50_Q6FBY9 Cluster: Putative acyl-CoA ligase; n=1;
Acinetobacter sp. ADP1|Rep: Putative acyl-CoA ligase -
Acinetobacter sp. (strain ADP1)
Length = 517
Score = 32.3 bits (70), Expect = 9.2
Identities = 15/47 (31%), Positives = 27/47 (57%), Gaps = 2/47 (4%)
Frame = +2
Query: 470 PEKKAFIMGD--RALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFME 604
P+K A I + L++ Q +NR A F++ G K G+V+++ +E
Sbjct: 11 PDKAACIFASTQQVLSYAQMNALANRCAHLFRQHGLKRGDVVSILLE 57
>UniRef50_Q0SEL9 Cluster: Non-ribosomal peptide synthetase; n=1;
Rhodococcus sp. RHA1|Rep: Non-ribosomal peptide
synthetase - Rhodococcus sp. (strain RHA1)
Length = 3046
Score = 32.3 bits (70), Expect = 9.2
Identities = 13/42 (30%), Positives = 24/42 (57%)
Frame = +2
Query: 470 PEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
P A G+ +++R+ +D+SNR+AW R+G +A+
Sbjct: 1756 PHAVALSYGNAVMSYRELDDWSNRLAWVLIRRGIGPEHHVAI 1797
>UniRef50_Q0SA57 Cluster: Long-chain-fatty-acid--CoA ligase; n=8;
Bacteria|Rep: Long-chain-fatty-acid--CoA ligase -
Rhodococcus sp. (strain RHA1)
Length = 523
Score = 32.3 bits (70), Expect = 9.2
Identities = 14/46 (30%), Positives = 27/46 (58%)
Frame = +2
Query: 458 AKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
A+ +P++ A I+GD +T+ + SN++A G + G+ +AL
Sbjct: 12 ARRFPDRDALILGDTRMTYADLDARSNQVANLLMSCGIEPGDKVAL 57
>UniRef50_Q0RMN6 Cluster: Putative non ribosomal peptide synthetase;
n=1; Frankia alni ACN14a|Rep: Putative non ribosomal
peptide synthetase - Frankia alni (strain ACN14a)
Length = 1119
Score = 32.3 bits (70), Expect = 9.2
Identities = 15/61 (24%), Positives = 35/61 (57%)
Frame = +2
Query: 419 KQGQSVVSRWAEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALF 598
++ +VV +A + P+ A + DR++T+R+ ++ S+R+A +R+ + +A+
Sbjct: 497 RRAPTVVDLFARQVERTPDAVAVVSADRSVTYRELDESSSRVAAALRRRRVEPETTVAVA 556
Query: 599 M 601
M
Sbjct: 557 M 557
>UniRef50_A7GTG0 Cluster: Amino acid adenylation domain; n=2;
Firmicutes|Rep: Amino acid adenylation domain - Bacillus
cereus subsp. cytotoxis NVH 391-98
Length = 2031
Score = 32.3 bits (70), Expect = 9.2
Identities = 15/48 (31%), Positives = 26/48 (54%)
Frame = +2
Query: 452 EIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
E K P+ A GD +T+ + + SNR+A + +G K G++I +
Sbjct: 792 EQCKQTPQAIAIEYGDEKVTYSELDHLSNRLAHCLREKGVKRGDLIGI 839
>UniRef50_A6DM14 Cluster: Cytochrome c5530 family protein; n=1;
Lentisphaera araneosa HTCC2155|Rep: Cytochrome c5530
family protein - Lentisphaera araneosa HTCC2155
Length = 2057
Score = 32.3 bits (70), Expect = 9.2
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 2/74 (2%)
Frame = +2
Query: 287 ATLGAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATMFRIWRWEKQGQSVVSRWA--EIA 460
A L ++TGDR + + +WKKT DFL R + T F++ S +RW +
Sbjct: 1416 AELAEEMITGDRTKAMMVWKKT---DFLADRNVTPTRFKLDLIGSADLSYENRWVVEKDG 1472
Query: 461 KLYPEKKAFIMGDR 502
+ Y + F G++
Sbjct: 1473 QFYISDQTFTTGNQ 1486
>UniRef50_A5UQX5 Cluster: AMP-dependent synthetase and ligase; n=2;
Bacteria|Rep: AMP-dependent synthetase and ligase -
Roseiflexus sp. RS-1
Length = 560
Score = 32.3 bits (70), Expect = 9.2
Identities = 15/45 (33%), Positives = 26/45 (57%)
Frame = +2
Query: 461 KLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIAL 595
+++PEK + GDR LT+ R+A +RQG + G+ +A+
Sbjct: 39 RVFPEKTGIVDGDRRLTYAAFGARVYRLANALRRQGVEPGDRVAI 83
>UniRef50_A0QHN3 Cluster: Syringomycin synthetase; n=3; Mycobacterium
avium|Rep: Syringomycin synthetase - Mycobacterium avium
(strain 104)
Length = 6212
Score = 32.3 bits (70), Expect = 9.2
Identities = 16/51 (31%), Positives = 31/51 (60%)
Frame = +2
Query: 449 AEIAKLYPEKKAFIMGDRALTFRQGEDFSNRIAWYFKRQGFKSGEVIALFM 601
A++A+ PE A G+R+ T+R+ + +NR+A +G + GE +A+ +
Sbjct: 1603 AQVART-PEAVAISCGERSWTYRELDSSANRLARVLAGRGARPGERVAVLV 1652
>UniRef50_Q4DTW0 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma cruzi|Rep: Putative uncharacterized protein
- Trypanosoma cruzi
Length = 909
Score = 32.3 bits (70), Expect = 9.2
Identities = 17/70 (24%), Positives = 31/70 (44%)
Frame = +2
Query: 245 GWLLRGSPTMMSAVATLGAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATMFRIWRWEKQ 424
G L +PT + +TL + LW++ + + + LA +F WRW
Sbjct: 583 GLLTLSTPTPHAISSTLQMLPRKEQKRVLFQLWREQARMSYAPRLLRLAQLFSRWRWRTY 642
Query: 425 GQSVVSRWAE 454
Q +++ +AE
Sbjct: 643 QQEIINYFAE 652
>UniRef50_Q4WVX2 Cluster: Ubiquitin C-terminal hydrolase, putative;
n=6; Trichocomaceae|Rep: Ubiquitin C-terminal hydrolase,
putative - Aspergillus fumigatus (Sartorya fumigata)
Length = 679
Score = 32.3 bits (70), Expect = 9.2
Identities = 18/46 (39%), Positives = 26/46 (56%)
Frame = +1
Query: 343 EEDAQEGFSRSKGTVSDNVQDMALGKTRPVSGVKVGGNSEAVSGKE 480
++DAQE FS+ G V VQ +TR + G+K+ G E + G E
Sbjct: 223 QQDAQEYFSKVVGQVDHEVQQATKRRTRNL-GLKMAGPVENIIGAE 267
>UniRef50_A7ESR0 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 503
Score = 32.3 bits (70), Expect = 9.2
Identities = 16/67 (23%), Positives = 30/67 (44%), Gaps = 2/67 (2%)
Frame = +2
Query: 248 WLLRGSPTMMSAVATL--GAYLLTGDRYQWIYLWKKTHKRDFLGLRVLLATMFRIWRWEK 421
++LRG T + + L+TGD W+ LW +R R + + W +
Sbjct: 12 YILRGHATPIHVAKFIRGNTRLITGDAEGWVVLWSLETRRGVAVWRAHGGVLLGVGEWGE 71
Query: 422 QGQSVVS 442
+G+ +V+
Sbjct: 72 RGEGIVT 78
>UniRef50_O27872 Cluster: Putative uncharacterized protein; n=1;
Methanothermobacter thermautotrophicus str. Delta H|Rep:
Putative uncharacterized protein - Methanobacterium
thermoautotrophicum
Length = 248
Score = 32.3 bits (70), Expect = 9.2
Identities = 18/45 (40%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Frame = -3
Query: 359 SCASSSKGKSIG-IYHRSIDKLPASQ-QRSSWSESRVEAIPVQLL 231
SC +SKGK +G + R I L A + R W+E +E IP++ L
Sbjct: 77 SCRLTSKGKLMGAVLSRFIASLDAVRLHRDFWNEHSIEVIPLEFL 121
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 609,827,153
Number of Sequences: 1657284
Number of extensions: 12962487
Number of successful extensions: 37459
Number of sequences better than 10.0: 123
Number of HSP's better than 10.0 without gapping: 36201
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37446
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 43147568152
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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