Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12d21r
(741 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VEJ3 Cluster: Pyrroline-5-carboxylate reductase; n=14... 219 6e-56
UniRef50_A6C9N7 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 195 8e-49
UniRef50_Q8MUT0 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 186 4e-46
UniRef50_P54904 Cluster: Pyrroline-5-carboxylate reductase; n=11... 186 5e-46
UniRef50_UPI000058613C Cluster: PREDICTED: similar to pyrroline-... 184 2e-45
UniRef50_A7HA48 Cluster: Pyrroline-5-carboxylate reductase; n=16... 184 2e-45
UniRef50_A6PTF6 Cluster: Pyrroline-5-carboxylate reductase precu... 184 3e-45
UniRef50_Q5EI64 Cluster: Pyrroline-5-carboxylate reductase; n=10... 181 1e-44
UniRef50_Q8GE04 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 177 3e-43
UniRef50_A7SQR3 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 177 3e-43
UniRef50_A5D185 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 176 5e-43
UniRef50_Q9HH99 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 172 9e-42
UniRef50_A4M789 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 171 2e-41
UniRef50_P32322 Cluster: Pyrroline-5-carboxylate reductase 1; n=... 170 4e-41
UniRef50_Q2BA85 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 167 2e-40
UniRef50_A6TR68 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 167 2e-40
UniRef50_Q1IRM0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 167 3e-40
UniRef50_P74572 Cluster: Pyrroline-5-carboxylate reductase; n=14... 167 3e-40
UniRef50_UPI00015C417B Cluster: pyrroline-5-carboxylate reductas... 166 4e-40
UniRef50_A5N0V3 Cluster: ProC2; n=1; Clostridium kluyveri DSM 55... 166 4e-40
UniRef50_A0WB61 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 166 4e-40
UniRef50_Q7UTG7 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 165 1e-39
UniRef50_A7SC14 Cluster: Predicted protein; n=1; Nematostella ve... 165 1e-39
UniRef50_Q00XH4 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 164 2e-39
UniRef50_UPI0000D556D2 Cluster: PREDICTED: similar to CG6009-PA;... 161 1e-38
UniRef50_Q8RA68 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 161 2e-38
UniRef50_Q9X8G1 Cluster: Pyrroline-5-carboxylate reductase; n=11... 160 4e-38
UniRef50_Q8KG91 Cluster: Pyrroline-5-carboxylate reductase; n=10... 159 5e-38
UniRef50_A7RN43 Cluster: Predicted protein; n=1; Nematostella ve... 159 5e-38
UniRef50_Q27722 Cluster: Pyrroline carboxylate reductase; n=8; P... 158 1e-37
UniRef50_Q97R93 Cluster: Pyrroline-5-carboxylate reductase; n=13... 158 2e-37
UniRef50_Q97E64 Cluster: Pyrroline-5-carboxylate reductase; n=10... 157 3e-37
UniRef50_A6BFA0 Cluster: Putative uncharacterized protein; n=1; ... 156 6e-37
UniRef50_A0LDU8 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 156 6e-37
UniRef50_Q6NP47 Cluster: Pyrroline-5-carboxylate reductase; n=10... 156 6e-37
UniRef50_Q1F0K7 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 155 1e-36
UniRef50_Q0AYD4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 153 3e-36
UniRef50_UPI00015B577C Cluster: PREDICTED: similar to GA19292-PA... 153 4e-36
UniRef50_Q4SMN2 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 153 4e-36
UniRef50_Q3AAH4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 152 8e-36
UniRef50_Q4QFY6 Cluster: Pyrroline-5-carboxylate reductase; n=7;... 151 2e-35
UniRef50_A5Z6I9 Cluster: Putative uncharacterized protein; n=1; ... 151 2e-35
UniRef50_UPI000051A719 Cluster: PREDICTED: similar to Pyrroline ... 149 7e-35
UniRef50_Q6NJK7 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 147 2e-34
UniRef50_A6G2U4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 147 2e-34
UniRef50_A3DD78 Cluster: Pyrroline-5-carboxylate reductase precu... 147 2e-34
UniRef50_Q8S488 Cluster: Delta-1-pyrroline-5-carboxylate reducta... 145 9e-34
UniRef50_P0A9L9 Cluster: Pyrroline-5-carboxylate reductase; n=65... 145 1e-33
UniRef50_Q9P7Y7 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 145 1e-33
UniRef50_Q86ER8 Cluster: Clone ZZD150 mRNA sequence; n=3; Schist... 144 2e-33
UniRef50_Q0SF18 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 142 6e-33
UniRef50_Q5KFS4 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 140 2e-32
UniRef50_Q8F631 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 140 3e-32
UniRef50_A0K0A3 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 140 3e-32
UniRef50_Q2ZZM3 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 140 4e-32
UniRef50_Q53H96 Cluster: Pyrroline-5-carboxylate reductase-like ... 140 4e-32
UniRef50_Q11141 Cluster: Pyrroline-5-carboxylate reductase; n=18... 139 6e-32
UniRef50_Q6AL13 Cluster: Related to pyrroline-5-carboxylate redu... 138 2e-31
UniRef50_P0C1E4 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 138 2e-31
UniRef50_Q67QH2 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 137 2e-31
UniRef50_Q64E79 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 136 4e-31
UniRef50_P14383 Cluster: Pyrroline-5-carboxylate reductase 1; n=... 136 5e-31
UniRef50_Q5KXH0 Cluster: Pyrroline-5-carboxylate reductase; n=13... 136 7e-31
UniRef50_Q8U084 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 135 1e-30
UniRef50_A4J3P9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 134 3e-30
UniRef50_Q233Y5 Cluster: Pyrroline-5-carboxylate reductase famil... 133 4e-30
UniRef50_A2EU21 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 132 7e-30
UniRef50_P22008 Cluster: Pyrroline-5-carboxylate reductase; n=21... 132 9e-30
UniRef50_Q48P99 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 132 1e-29
UniRef50_Q0ICK3 Cluster: Pyrroline-5-carboxylate reductase; n=17... 131 2e-29
UniRef50_A7GVZ9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 131 2e-29
UniRef50_Q02WW5 Cluster: Pyrroline-5-carboxylate reductase; n=12... 130 4e-29
UniRef50_Q836Y3 Cluster: Pyrroline-5-carboxylate reductase, puta... 129 8e-29
UniRef50_P54552 Cluster: Pyrroline-5-carboxylate reductase 2; n=... 129 8e-29
UniRef50_Q312A7 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 128 1e-28
UniRef50_Q6AAZ1 Cluster: Putative delta-1-pyrroline-5-carboxylat... 128 1e-28
UniRef50_P54893 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 128 2e-28
UniRef50_Q8EU76 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 127 3e-28
UniRef50_Q6CEN0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 126 4e-28
UniRef50_A2QIA2 Cluster: Catalytic activity: L-proline + NAD(P)(... 126 4e-28
UniRef50_Q6KZ51 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 126 6e-28
UniRef50_Q831S6 Cluster: Pyrroline-5-carboxylate reductase, puta... 124 2e-27
UniRef50_A3LST6 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 124 2e-27
UniRef50_Q8YCL9 Cluster: PYRROLINE-5-CARBOXYLATE REDUCTASE; n=11... 123 4e-27
UniRef50_Q83A21 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 123 4e-27
UniRef50_A5CND2 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 123 4e-27
UniRef50_Q1GJ10 Cluster: Pyrroline-5-carboxylate reductase; n=24... 122 9e-27
UniRef50_A5WCA1 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 122 9e-27
UniRef50_A3H628 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 122 9e-27
UniRef50_Q9HLT6 Cluster: Pyrroline-5-carboxylate reductase relat... 122 1e-26
UniRef50_Q8DJK6 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 121 2e-26
UniRef50_Q12740 Cluster: Pyrroline-5-carboxylate reductase; n=7;... 121 2e-26
UniRef50_Q0C2D9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 121 2e-26
UniRef50_A1TY17 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 120 3e-26
UniRef50_A5UQB8 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 120 4e-26
UniRef50_Q1AVY1 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 119 7e-26
UniRef50_Q1FII0 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 119 9e-26
UniRef50_Q9KCR6 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 118 1e-25
UniRef50_Q82X95 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 118 1e-25
UniRef50_Q1UAB2 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 118 2e-25
UniRef50_A6DTF8 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 118 2e-25
UniRef50_A3IBB9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 118 2e-25
UniRef50_Q9PA08 Cluster: Pyrroline-5-carboxylate reductase; n=14... 116 5e-25
UniRef50_Q6N1N9 Cluster: Pyrroline-5-carboxylate reductase; n=23... 116 6e-25
UniRef50_Q1MPA3 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 116 6e-25
UniRef50_Q9CPE8 Cluster: Pyrroline-5-carboxylate reductase; n=93... 116 6e-25
UniRef50_A6GTV0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 116 8e-25
UniRef50_Q20848 Cluster: Putative pyrroline-5-carboxylate reduct... 116 8e-25
UniRef50_Q89DI5 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 114 2e-24
UniRef50_Q88Z19 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 114 2e-24
UniRef50_A6Q4P9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 114 2e-24
UniRef50_P32263 Cluster: Pyrroline-5-carboxylate reductase; n=7;... 114 2e-24
UniRef50_O66553 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 114 2e-24
UniRef50_A3UFN9 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 113 3e-24
UniRef50_Q4TIV0 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 113 4e-24
UniRef50_Q0VL32 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 113 4e-24
UniRef50_A3ERR0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 113 4e-24
UniRef50_Q12641 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 113 4e-24
UniRef50_Q3Y1B7 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 112 8e-24
UniRef50_A0NYJ6 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 112 8e-24
UniRef50_Q0U2X1 Cluster: Putative uncharacterized protein; n=1; ... 112 8e-24
UniRef50_A6SCY1 Cluster: Putative uncharacterized protein; n=2; ... 112 8e-24
UniRef50_Q5WH55 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 111 2e-23
UniRef50_Q0EXW9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 111 2e-23
UniRef50_Q9YFV4 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 111 2e-23
UniRef50_UPI000038E2C3 Cluster: hypothetical protein Faci_030013... 111 2e-23
UniRef50_Q2UTF9 Cluster: Pyrroline-5-carboxylate reductase; n=5;... 111 2e-23
UniRef50_Q9WZ47 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 109 9e-23
UniRef50_Q3MCP7 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 109 9e-23
UniRef50_Q18YN1 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 109 9e-23
UniRef50_A1AVF5 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 108 1e-22
UniRef50_A3HTL9 Cluster: Putative pyrroline-5-carboxylate reduct... 108 2e-22
UniRef50_Q974L3 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 108 2e-22
UniRef50_P27771 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 108 2e-22
UniRef50_Q6MC43 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 107 2e-22
UniRef50_Q5XE84 Cluster: Pyrroline-5-carboxylate reductase; n=14... 107 2e-22
UniRef50_A1IB74 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 107 4e-22
UniRef50_A1H9S1 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 106 5e-22
UniRef50_Q1YVF3 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 106 7e-22
UniRef50_Q1PLB2 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 106 7e-22
UniRef50_Q5NMY3 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 105 1e-21
UniRef50_A4SZT4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 105 2e-21
UniRef50_Q9KEG5 Cluster: Pyrroline-5-carboxylate reductase; n=11... 104 2e-21
UniRef50_A2QNB5 Cluster: Catalytic activity: L-proline + NAD(P)(... 104 2e-21
UniRef50_A7D089 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 104 3e-21
UniRef50_A5FLP2 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 104 3e-21
UniRef50_Q7VYN6 Cluster: Pyrroline-5-carboxylate reductase; n=45... 103 3e-21
UniRef50_Q6LML8 Cluster: Pyrroline-5-carboxylate reductase; n=7;... 103 3e-21
UniRef50_A4XKQ2 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 103 3e-21
UniRef50_Q5QY55 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 103 6e-21
UniRef50_Q087E8 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 102 8e-21
UniRef50_Q04FB4 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 102 1e-20
UniRef50_A4R602 Cluster: Putative uncharacterized protein; n=1; ... 101 1e-20
UniRef50_Q7M801 Cluster: PUTATIVE PYRROLINE-5-CARBOXYLATE REDUCT... 100 3e-20
UniRef50_Q3ZWQ2 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 100 3e-20
UniRef50_Q9K1N1 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 99 6e-20
UniRef50_Q2S8M4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 99 6e-20
UniRef50_Q9FDK7 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 100 7e-20
UniRef50_Q21EI2 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 100 7e-20
UniRef50_A0Z2R8 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 100 7e-20
UniRef50_Q7WJW6 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 99 1e-19
UniRef50_Q5WIM0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 99 1e-19
UniRef50_A5VEU4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 99 1e-19
UniRef50_A6VSQ3 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 99 1e-19
UniRef50_Q8G5S6 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 98 2e-19
UniRef50_Q0BPP7 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 98 2e-19
UniRef50_Q0PQR2 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 97 4e-19
UniRef50_A1W308 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 97 4e-19
UniRef50_A6NV19 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 96 7e-19
UniRef50_A4BKC4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 96 7e-19
UniRef50_Q5ZTZ3 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 96 9e-19
UniRef50_A6QB49 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 95 2e-18
UniRef50_A7EEE1 Cluster: Putative uncharacterized protein; n=1; ... 95 2e-18
UniRef50_A6RSV4 Cluster: Putative uncharacterized protein; n=1; ... 95 2e-18
UniRef50_A7BDU0 Cluster: Putative uncharacterized protein; n=1; ... 94 3e-18
UniRef50_Q2PIP2 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 94 4e-18
UniRef50_A2BJN9 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 94 4e-18
UniRef50_Q5ZP97 Cluster: Pyrroline carboxylate reductase-like pr... 93 5e-18
UniRef50_UPI0000E87E64 Cluster: pyrroline-5-carboxylate reductas... 93 9e-18
UniRef50_Q9AAU9 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 93 9e-18
UniRef50_Q5HFR9 Cluster: Pyrroline-5-carboxylate reductase; n=16... 92 1e-17
UniRef50_UPI00015BCA3C Cluster: UPI00015BCA3C related cluster; n... 92 2e-17
UniRef50_Q0UG51 Cluster: Putative uncharacterized protein; n=1; ... 92 2e-17
UniRef50_Q0CFR0 Cluster: Predicted protein; n=3; Aspergillus|Rep... 92 2e-17
UniRef50_Q03V33 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 91 2e-17
UniRef50_UPI0000E1F031 Cluster: PREDICTED: similar to Pyrroline-... 91 3e-17
UniRef50_Q8A6I2 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 91 3e-17
UniRef50_A4A9D5 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 90 6e-17
UniRef50_Q8D3C2 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 89 1e-16
UniRef50_Q1GX51 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 89 1e-16
UniRef50_A0M2T1 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 89 1e-16
UniRef50_Q18J37 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 89 1e-16
UniRef50_Q1VVL6 Cluster: Pyrroline-5-carboxylate reductase; n=9;... 88 2e-16
UniRef50_Q5FRU8 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 87 4e-16
UniRef50_A7LUS1 Cluster: Putative uncharacterized protein; n=1; ... 87 4e-16
UniRef50_Q11WK0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 86 7e-16
UniRef50_Q88GE6 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 86 1e-15
UniRef50_Q2NCY1 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 86 1e-15
UniRef50_Q1U6D2 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 85 1e-15
UniRef50_Q4HSX5 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 85 2e-15
UniRef50_A3X4C4 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 84 4e-15
UniRef50_Q0P9H8 Cluster: Pyrroline-5-carboxylate reductase; n=10... 83 5e-15
UniRef50_A7JJ83 Cluster: Pyrroline-5-carboxylate reductase; n=11... 83 5e-15
UniRef50_Q1NBI0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 83 9e-15
UniRef50_Q4WFG1 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 83 9e-15
UniRef50_A7C3U2 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 82 2e-14
UniRef50_A0RR69 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 82 2e-14
UniRef50_A3VSN0 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 81 2e-14
UniRef50_Q54IL7 Cluster: Pyrroline-5-carboxylate reductase; n=3;... 81 2e-14
UniRef50_UPI000050FC3D Cluster: COG0345: Pyrroline-5-carboxylate... 81 3e-14
UniRef50_A6LE67 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 81 4e-14
UniRef50_Q6F272 Cluster: 1-pyrroline-5-carboxylate reductase; n=... 80 6e-14
UniRef50_Q1M3U8 Cluster: Putative pyrroline-5-carboxylate reduct... 79 1e-13
UniRef50_A0HA22 Cluster: NADP oxidoreductase, coenzyme F420-depe... 77 3e-13
UniRef50_A3M414 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 77 6e-13
UniRef50_Q0AL89 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 76 8e-13
UniRef50_A1B1A3 Cluster: NADP oxidoreductase, coenzyme F420-depe... 76 8e-13
UniRef50_Q7YYR6 Cluster: Pyrroline-5-carboxylate reductase, poss... 76 8e-13
UniRef50_A7AD19 Cluster: Putative uncharacterized protein; n=1; ... 76 1e-12
UniRef50_A6DA85 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 76 1e-12
UniRef50_Q7VHX1 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 75 2e-12
UniRef50_Q5FK14 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 74 4e-12
UniRef50_A3Y9M8 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 71 3e-11
UniRef50_A3K0L9 Cluster: Putative pyrroline-5-carboxylate reduct... 71 3e-11
UniRef50_A5EV67 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 71 4e-11
UniRef50_Q41BC1 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 69 9e-11
UniRef50_Q0G398 Cluster: Putative pyrroline-5-carboxylate reduct... 69 2e-10
UniRef50_A2A043 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 68 2e-10
UniRef50_A3SP40 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 68 3e-10
UniRef50_Q83FH8 Cluster: Pyrroline-5-carboxylate reductase; n=2;... 67 5e-10
UniRef50_A3UDP5 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 67 5e-10
UniRef50_Q59UW8 Cluster: Putative uncharacterized protein; n=2; ... 65 1e-09
UniRef50_Q67T73 Cluster: ComE operon protein 4; n=1; Symbiobacte... 64 3e-09
UniRef50_Q5FGR8 Cluster: Pyrroline-5-carboxylate reductase; n=6;... 63 6e-09
UniRef50_O25773 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 62 2e-08
UniRef50_Q2FQL0 Cluster: NADP oxidoreductase, coenzyme F420-depe... 57 5e-07
UniRef50_Q6MQK1 Cluster: ProC protein; n=1; Bdellovibrio bacteri... 56 1e-06
UniRef50_A4R344 Cluster: Putative uncharacterized protein; n=1; ... 54 4e-06
UniRef50_UPI0000E45EAB Cluster: PREDICTED: similar to pyrroline-... 54 5e-06
UniRef50_Q4ML40 Cluster: Pyrroline-5-carboxylate reductase; n=1;... 52 2e-05
UniRef50_A6RTE4 Cluster: Putative uncharacterized protein; n=2; ... 51 3e-05
UniRef50_A1FCT9 Cluster: Pyrroline-5-carboxylate reductase-like;... 50 5e-05
UniRef50_UPI00015BAEC8 Cluster: pyrroline-5-carboxylate reductas... 50 8e-05
UniRef50_Q4FKY2 Cluster: Delta 1-pyrroline-5-carboxylate reducta... 49 1e-04
UniRef50_Q8ZW86 Cluster: Pyrroline-5-carboxylate reductase; n=4;... 40 0.064
UniRef50_Q8TGP2 Cluster: Uncharacterized protein YER023C-A; n=2;... 40 0.085
UniRef50_UPI0000DAE5EB Cluster: hypothetical protein Rgryl_01000... 38 0.20
UniRef50_Q3K4H0 Cluster: Rhs element Vgr protein precursor; n=4;... 36 1.0
UniRef50_A2C5X0 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_Q57Z15 Cluster: Putative uncharacterized protein; n=1; ... 34 3.2
UniRef50_Q7NSK8 Cluster: Malonyl CoA-acyl carrier protein transa... 34 4.2
UniRef50_Q01U58 Cluster: Ig family protein precursor; n=1; Solib... 34 4.2
UniRef50_Q0W1B5 Cluster: Putative ATP-dependent phosphofructokin... 34 4.2
UniRef50_UPI0000F2015F Cluster: PREDICTED: hypothetical protein;... 33 7.4
UniRef50_UPI000066001A Cluster: Uncharacterized protein C7orf43.... 33 7.4
UniRef50_Q4RGT0 Cluster: Chromosome 4 SCAF15093, whole genome sh... 33 7.4
UniRef50_A1WWC4 Cluster: Transcriptional regulator, Fis family p... 33 7.4
UniRef50_Q5YZH9 Cluster: Potassium-transporting ATPase A chain; ... 33 7.4
UniRef50_Q7NPM8 Cluster: Gll0027 protein; n=1; Gloeobacter viola... 33 9.7
UniRef50_A3TM86 Cluster: Putative uncharacterized protein; n=1; ... 33 9.7
>UniRef50_Q9VEJ3 Cluster: Pyrroline-5-carboxylate reductase; n=14;
Endopterygota|Rep: Pyrroline-5-carboxylate reductase -
Drosophila melanogaster (Fruit fly)
Length = 273
Score = 219 bits (535), Expect = 6e-56
Identities = 109/186 (58%), Positives = 140/186 (75%), Gaps = 1/186 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L EI+ P + KLF+SVAMGIT++T+ES+L +ARVIRVMPN PA+V G + F RG+K
Sbjct: 83 LSEIQ--PLSSGKLFLSVAMGITLSTIESSLSPQARVIRVMPNLPAVVCSGCSVFVRGSK 140
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
AT DA +T +L ++VGTC+ V E Q+D +TALSGSGPAYV+++IE+LADG V G+PRD
Sbjct: 141 ATDADADITQKLLQSVGTCEPVDESQLDVVTALSGSGPAYVFVMIEALADGAVHMGMPRD 200
Query: 322 LALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
LA RLA+QT LG+ MV+ +G HP LKD VTSPAGSTA LE +GFR+A+ GAV
Sbjct: 201 LAYRLASQTVLGAGHMVRDSGMHPGQLKDGVTSPAGSTAAALRQLELSGFRAAVSGAVEQ 260
Query: 145 AVDRCK 128
A RC+
Sbjct: 261 ATLRCR 266
>UniRef50_A6C9N7 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Planctomyces maris DSM 8797|Rep: Pyrroline-5-carboxylate
reductase - Planctomyces maris DSM 8797
Length = 274
Score = 195 bits (476), Expect = 8e-49
Identities = 99/184 (53%), Positives = 131/184 (71%), Gaps = 1/184 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+EIK+ ++++ L IS+A G ++ L R+IRVMPNTP LVK+GA+AF+RG +
Sbjct: 84 LQEIKSSVTSQH-LLISIAAGCPLSLFLDTLGEFTRMIRVMPNTPCLVKQGASAFARGGQ 142
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
A+ EDA L L VG EVPE Q+DA+T LSGSGPAY+Y +IE+L+DGGVR GLPR
Sbjct: 143 ASTEDATLVESLLSTVGIAFEVPESQLDAVTGLSGSGPAYIYQVIEALSDGGVRVGLPRQ 202
Query: 322 LALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+A +LAAQT G+A MV +TG+HP LKD VTSP G+T G + LE G R++++ AVSA
Sbjct: 203 IATQLAAQTVKGAAEMVLQTGEHPGTLKDAVTSPGGTTIAGIHALEAGGLRNSLMNAVSA 262
Query: 145 AVDR 134
A R
Sbjct: 263 ATSR 266
>UniRef50_Q8MUT0 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Tigriopus californicus|Rep: Pyrroline-5-carboxylate
reductase - Tigriopus californicus (Marine copepod)
Length = 270
Score = 186 bits (454), Expect = 4e-46
Identities = 90/185 (48%), Positives = 131/185 (70%), Gaps = 1/185 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L +IK+L ++K L +S+A G+ +A ++++L +++++R+MPNTP +V+EG + F G +
Sbjct: 84 LPDIKSLVASK--LMVSIAAGVQLAQLQADLNPDSKIVRLMPNTPCIVREGVSVFCSGPQ 141
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
T +D QLF VG DEV E +DA+T +SGSGPAY+Y++IE++ADGGV+ GLPRD
Sbjct: 142 VTPQDNATVKQLFGTVGQIDEVKESMIDAVTGVSGSGPAYMYLIIEAMADGGVKQGLPRD 201
Query: 322 LALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
LA +LAAQT +G+ MV T HPA+LKD V SP G+T LEK+G R++I+ AV A
Sbjct: 202 LAYKLAAQTMVGAGRMVLDTHTHPAVLKDEVCSPGGTTITALDMLEKSGLRTSIMQAVEA 261
Query: 145 AVDRC 131
A RC
Sbjct: 262 ATKRC 266
>UniRef50_P54904 Cluster: Pyrroline-5-carboxylate reductase; n=11;
core eudicotyledons|Rep: Pyrroline-5-carboxylate
reductase - Arabidopsis thaliana (Mouse-ear cress)
Length = 276
Score = 186 bits (453), Expect = 5e-46
Identities = 98/187 (52%), Positives = 127/187 (67%), Gaps = 1/187 (0%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
A+ E+K+ S KNK+ +SVA GI + ++ + R IRVMPNTPA V E A+ S GT
Sbjct: 87 AVTELKSKLS-KNKILVSVAAGIKLNDLQE-WSGQDRFIRVMPNTPAAVGEAASVMSLGT 144
Query: 505 KATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
AT ED + + LF AVG + E DA+T LSGSGPAY+++ IE+LADGGV GLPR
Sbjct: 145 GATEEDGAIVAMLFGAVGKILKADEKMFDAVTGLSGSGPAYIFLAIEALADGGVAAGLPR 204
Query: 325 DLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
+LAL LA+QT LG+A MV KTG HP +LKD+VTSP G+T G + LEK FR+ ++ AV
Sbjct: 205 ELALSLASQTVLGAATMVSKTGKHPGVLKDDVTSPGGTTIAGVHELEKGSFRATLMNAVV 264
Query: 148 AAVDRCK 128
AA R +
Sbjct: 265 AAAKRSR 271
>UniRef50_UPI000058613C Cluster: PREDICTED: similar to
pyrroline-5-carboxylate reductase 1; n=2;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyrroline-5-carboxylate reductase 1 - Strongylocentrotus
purpuratus
Length = 276
Score = 184 bits (449), Expect = 2e-45
Identities = 87/176 (49%), Positives = 124/176 (70%), Gaps = 1/176 (0%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+++LFIS+A GI++ +E+NLP +RV+R MPNTP +++EGA F+ G+ D +L
Sbjct: 89 RDQLFISLAAGISLDFIENNLPERSRVVRAMPNTPTIIREGATVFACGSHIKEGDNRLIQ 148
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
LF +G C E E +DA A+SG GPAY Y+ I++LADGGV+ GLPRD+A++LAAQT
Sbjct: 149 SLFSKLGICIEGDESIIDAAMAVSGCGPAYAYVAIDALADGGVKMGLPRDIAIKLAAQTL 208
Query: 292 LGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
LGSA MV + G HP+ LKD+V SP G+T + + LE+ GFR +I AV AA ++ +
Sbjct: 209 LGSAKMVLRGGKHPSQLKDDVCSPGGTTIDAIHELERGGFRKCLIEAVEAACNKAR 264
>UniRef50_A7HA48 Cluster: Pyrroline-5-carboxylate reductase; n=16;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Anaeromyxobacter sp. Fw109-5
Length = 276
Score = 184 bits (448), Expect = 2e-45
Identities = 90/174 (51%), Positives = 122/174 (70%), Gaps = 1/174 (0%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
KL +S+A G++IA + L + R++R MPNTPALV GA A +RG AT D + L
Sbjct: 93 KLVVSIAAGVSIAAIARKLGAGVRIVRTMPNTPALVGAGATALARGAHATDWDLEQARSL 152
Query: 466 FKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
F+AVGT V E+ +DA+T LSGSGPA+++++IE+LADGGV+ GL R +A+ LAAQT LG
Sbjct: 153 FQAVGTTVIVEEHHLDAVTGLSGSGPAFLFLVIEALADGGVKVGLARSVAMTLAAQTVLG 212
Query: 286 SAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
SA +V +TG+HP LKD VTSP G+ G + LE+ G R+A+I AV AA R +
Sbjct: 213 SAKLVLETGEHPGRLKDQVTSPGGTAIAGVHALEQGGLRAALIAAVEAATRRSR 266
>UniRef50_A6PTF6 Cluster: Pyrroline-5-carboxylate reductase
precursor; n=1; Victivallis vadensis ATCC BAA-548|Rep:
Pyrroline-5-carboxylate reductase precursor -
Victivallis vadensis ATCC BAA-548
Length = 267
Score = 184 bits (447), Expect = 3e-45
Identities = 94/182 (51%), Positives = 124/182 (68%), Gaps = 1/182 (0%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
A N+LF+S+ G++I + + L R++R+MPNTP LV GAA FS G KA ED LT
Sbjct: 87 AGNRLFLSIVAGVSIDRL-TELTGSERIVRIMPNTPMLVGRGAAGFSAGPKANEEDIALT 145
Query: 475 SQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
++ +VG V E MDA+TALSGSGPAYV+ I++LADGGV GLPRD+A +LAAQT
Sbjct: 146 ERILASVGIAFRVDEKYMDAVTALSGSGPAYVFEFIQALADGGVSEGLPRDMATQLAAQT 205
Query: 295 TLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 119
LG+A MV KTG HP +LKD VTSPAG+TA + +NGF + +I A+ A R + +
Sbjct: 206 VLGAAEMVLKTGTHPTVLKDQVTSPAGTTARALEVMYRNGFAATVIDAMHACARRSEELG 265
Query: 118 KQ 113
K+
Sbjct: 266 KK 267
>UniRef50_Q5EI64 Cluster: Pyrroline-5-carboxylate reductase; n=10;
cellular organisms|Rep: Pyrroline-5-carboxylate
reductase - Triticum aestivum (Wheat)
Length = 287
Score = 181 bits (441), Expect = 1e-44
Identities = 95/190 (50%), Positives = 123/190 (64%), Gaps = 1/190 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L E+K L S + KL +S+A GI + ++ + + R+IRVMPNTP+ V + A+ G
Sbjct: 99 LVELKPLLS-EEKLLVSIAAGIKMKDLQ-DWSGQRRIIRVMPNTPSAVGQAASVMCLGET 156
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
AT +D LF A+G E DA+T LSGSGPAY+++ IE++ADGGV GLPRD
Sbjct: 157 ATEKDENRVKSLFSAIGKVWTAEEKYFDAVTGLSGSGPAYIFLAIEAMADGGVAAGLPRD 216
Query: 322 LALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
LAL LAAQT LG+A MV +TG HP LKD VTSPAG+T G + LEK FR +I AV A
Sbjct: 217 LALGLAAQTVLGAATMVSETGKHPGQLKDQVTSPAGTTIAGVHELEKGSFRGTLINAVVA 276
Query: 145 AVDRCKIVKK 116
A RC+ + K
Sbjct: 277 ATTRCRELSK 286
>UniRef50_Q8GE04 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Heliobacillus mobilis|Rep: Pyrroline-5-carboxylate
reductase - Heliobacillus mobilis
Length = 274
Score = 177 bits (430), Expect = 3e-43
Identities = 88/173 (50%), Positives = 118/173 (68%), Gaps = 1/173 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L IS+A GIT+A +ES L E +IRVMPNTPAL+ +GA+A + G + +D Q L
Sbjct: 96 LVISIAAGITLAQLESWLSPEVPLIRVMPNTPALIGKGASALAGGRAVSEQDVQTAKALL 155
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
+AVG + +PE ++A+T SGSGPAYVY+ IE+L D GV+ GL RDLA +LA QT +GS
Sbjct: 156 EAVGIAEVLPETYLNAVTGFSGSGPAYVYLFIEALIDAGVKEGLTRDLARKLAIQTVIGS 215
Query: 283 A-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
A +++TG+HPA+ +D VTSP G+T G LE GFRSA+ AV A R +
Sbjct: 216 AQLLIETGNHPAIERDKVTSPGGTTIAGVQALEDGGFRSAVFAAVHAGTKRAR 268
>UniRef50_A7SQR3 Cluster: Predicted protein; n=3; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 269
Score = 177 bits (430), Expect = 3e-43
Identities = 88/184 (47%), Positives = 128/184 (69%), Gaps = 1/184 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L EI + + KN L +S+A G+++ ++E LP ++RV+RVMPN P LV+ GA+A++ G
Sbjct: 77 LSEIAPVITPKN-LVVSIAAGVSLKSMEKCLPHKSRVVRVMPNIPTLVRAGASAYALGHN 135
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
A +D++ +L AVG ++V E + A+T LSGSGPAY +M IE+LADGGV+ GLPR
Sbjct: 136 AIGDDSETVKRLMSAVGYVEQVREKDVAAVTGLSGSGPAYCFMAIEALADGGVKAGLPRQ 195
Query: 322 LALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+A+ LAA T +G+A +V +TG HP LKD+V SP GSTA + LE+ G R+ ++ AV A
Sbjct: 196 VAINLAAHTLMGAAKLVLETGKHPGELKDSVCSPEGSTAYAIHSLERAGLRATLMDAVDA 255
Query: 145 AVDR 134
A+ R
Sbjct: 256 ALRR 259
>UniRef50_A5D185 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Pelotomaculum thermopropionicum SI
Length = 273
Score = 176 bits (428), Expect = 5e-43
Identities = 95/186 (51%), Positives = 122/186 (65%), Gaps = 1/186 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
+KEI L L IS+A G+T A +ES L S V+RVMPNTP LV EGA+A S G
Sbjct: 83 MKEIAPLLRPGQTL-ISIAAGVTSAFIESFLNSPVPVVRVMPNTPCLVGEGASAVSAGKY 141
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
A E+ + +F A G EVPE +D +T LSGSGPAY+Y+++E L DG VR GLPRD
Sbjct: 142 AGRENMEKALAIFSAAGKAVEVPERLLDCVTGLSGSGPAYMYVILEGLIDGAVRLGLPRD 201
Query: 322 LALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
A LAAQT LG+A MV +TG+HPA LKD VT+P G+T G + LE+ R+ ++ AV A
Sbjct: 202 QARLLAAQTMLGAAKMVLETGEHPARLKDMVTTPGGTTIAGLFALEEGAVRALLMKAVEA 261
Query: 145 AVDRCK 128
A +R +
Sbjct: 262 AAERSR 267
>UniRef50_Q9HH99 Cluster: Pyrroline-5-carboxylate reductase; n=5;
cellular organisms|Rep: Pyrroline-5-carboxylate
reductase - Methanosarcina acetivorans
Length = 270
Score = 172 bits (418), Expect = 9e-42
Identities = 92/191 (48%), Positives = 127/191 (66%), Gaps = 1/191 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L +KN +++ KL IS+A G+ ++T E L RV+RVMPN A V E A+ + G
Sbjct: 81 LSNLKNEITSE-KLVISIAAGVPLSTYEDALLEGTRVVRVMPNIAATVSEAASGIAPGKN 139
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
AT ED + ++F AVGT +VPE MDA+T LSGSGPA+++ +IE++ADG V G+ R
Sbjct: 140 ATPEDLKAALEIFSAVGTAVQVPESLMDAVTGLSGSGPAFIFPVIEAMADGAVLEGMDRK 199
Query: 322 LALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
AL LAAQT LG+A M ++TG HP LKD VTSPAG+T +G + LE+ G R+A + AV
Sbjct: 200 SALTLAAQTVLGAAKMALETGMHPGELKDMVTSPAGTTIQGIHSLEEAGIRAAFMNAVIR 259
Query: 145 AVDRCKIVKKQ 113
A +R K + K+
Sbjct: 260 ASERSKELGKK 270
>UniRef50_A4M789 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Petrotoga mobilis SJ95
Length = 274
Score = 171 bits (415), Expect = 2e-41
Identities = 90/191 (47%), Positives = 124/191 (64%), Gaps = 1/191 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+EI + S +NK+ IS+A G+++ ++ LP+ +++IR MPNTP LV EG A S+
Sbjct: 80 LEEISS--SCENKIVISIAAGVSLRHLDKALPTSSKIIRAMPNTPILVGEGVIAISKKKN 137
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
D + ++ ++VG V E MDAITALSGSGPAYVYM+IE+L+DGGV GLPR+
Sbjct: 138 VDENDLKRVKEILESVGKVYLVEEDIMDAITALSGSGPAYVYMMIEALSDGGVLMGLPRE 197
Query: 322 LALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
L+ AA+T LG+A MV +TG HP LKD VTSP G+ +G LE +G R ++ AV
Sbjct: 198 LSTEFAARTLLGAARMVLETGKHPGELKDMVTSPGGTAIKGIEVLESHGLRGILMDAVKE 257
Query: 145 AVDRCKIVKKQ 113
A R K + Q
Sbjct: 258 ATIRSKELNSQ 268
>UniRef50_P32322 Cluster: Pyrroline-5-carboxylate reductase 1; n=61;
Euteleostomi|Rep: Pyrroline-5-carboxylate reductase 1 -
Homo sapiens (Human)
Length = 319
Score = 170 bits (413), Expect = 4e-41
Identities = 86/176 (48%), Positives = 116/176 (65%), Gaps = 4/176 (2%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPS---EARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+ +S A G+TI+++E L + RVIR M NTP +V+EGA ++ GT A ED +L
Sbjct: 91 IVVSCAAGVTISSIEKKLSAFRPAPRVIRCMTNTPVVVREGATVYATGTHAQVEDGRLME 150
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
QL +VG C EV E +DA+T LSGSGPAY + +++LADGGV+ GLPR LA+RL AQ
Sbjct: 151 QLLSSVGFCTEVEEDLIDAVTGLSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQAL 210
Query: 292 LGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
LG+A M + + HP LKDNV+SP G+T + LE GFRS +I AV A+ R +
Sbjct: 211 LGAAKMLLHSEQHPGQLKDNVSSPGGATIHALHVLESGGFRSLLINAVEASCIRTR 266
>UniRef50_Q2BA85 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Firmicutes|Rep: Pyrroline-5-carboxylate reductase -
Bacillus sp. NRRL B-14911
Length = 272
Score = 167 bits (407), Expect = 2e-40
Identities = 84/183 (45%), Positives = 123/183 (67%), Gaps = 2/183 (1%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
+++ + I++A GI++A ++S E + IR MPNTP+LV EG +A + + T ++
Sbjct: 88 SEDAIIITIAAGISLAFLQSAFGREIKAIRSMPNTPSLVGEGMSALAASRQVTEKERLEA 147
Query: 475 SQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
++LF++ G + + E MD+I A+SGS PAYVYM IE+LADGGV GLPR+ + RLAAQ
Sbjct: 148 AELFESFGKAEFIEEKLMDSIPAISGSSPAYVYMFIEALADGGVLQGLPRETSYRLAAQA 207
Query: 295 TLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK-IV 122
LG+A MV +TG HP LKD V +P G+T E LEK GFRS++I A+ + D+ + +
Sbjct: 208 VLGAAKMVLETGKHPGELKDQVCTPGGATIEAVAELEKQGFRSSVISAMHSCTDKSRQLA 267
Query: 121 KKQ 113
KKQ
Sbjct: 268 KKQ 270
>UniRef50_A6TR68 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Alkaliphilus metalliredigens QYMF|Rep:
Pyrroline-5-carboxylate reductase - Alkaliphilus
metalliredigens QYMF
Length = 281
Score = 167 bits (406), Expect = 2e-40
Identities = 86/186 (46%), Positives = 118/186 (63%), Gaps = 1/186 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+EI+ ++++ + +SVA G++IA +E +VIR MPNTP V EG A +
Sbjct: 85 LEEIREFITSEH-VIVSVAAGVSIALIEGFFDKPVKVIRTMPNTPVFVGEGMTAVTPNNY 143
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
T ++ + ++F ++G + + E MDAI A+SGS PAYVY IE+LADGGV G+PRD
Sbjct: 144 VTDDELRTVVEIFSSMGEVEIIGEGIMDAIPAISGSSPAYVYTFIEALADGGVSLGIPRD 203
Query: 322 LALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
A + AAQ G+A MV ++ +HP +LKD V SPAGST E Y LEKNGFR II A+ A
Sbjct: 204 KAYKFAAQAVYGAAKMVLESNEHPGVLKDQVCSPAGSTIEALYVLEKNGFRGTIIEAMKA 263
Query: 145 AVDRCK 128
R K
Sbjct: 264 CTHRAK 269
>UniRef50_Q1IRM0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Acidobacteria bacterium Ellin345|Rep:
Pyrroline-5-carboxylate reductase - Acidobacteria
bacterium (strain Ellin345)
Length = 280
Score = 167 bits (405), Expect = 3e-40
Identities = 85/175 (48%), Positives = 111/175 (63%), Gaps = 1/175 (0%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
N+L ISVA + A +E L ++ +IR MPNTP+++ G +G ATA L
Sbjct: 101 NQLLISVAASVPTAYMEERLAAKVPIIRAMPNTPSMLGAGMTGICKGAHATAAQLDLAQA 160
Query: 469 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
+F VG V E MDA+T LS SGPA++Y++IESLA+ GV+ GLPRDLA LAAQTT+
Sbjct: 161 MFNTVGRTAIVEEKHMDAVTGLSASGPAFIYIIIESLAEAGVKVGLPRDLATLLAAQTTM 220
Query: 289 GSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
G+A +V +TG HPA LKD VT+PAG T +G LE+ R +I AV A R K
Sbjct: 221 GAAQVVLETGQHPAQLKDAVTTPAGCTIDGILELEEGKLRVTLIKAVVKAAQRAK 275
>UniRef50_P74572 Cluster: Pyrroline-5-carboxylate reductase; n=14;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Synechocystis sp. (strain PCC 6803)
Length = 267
Score = 167 bits (405), Expect = 3e-40
Identities = 88/182 (48%), Positives = 114/182 (62%), Gaps = 1/182 (0%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
A L IS+ G+++ ++ P A +IR MPNTPA V G A + +
Sbjct: 87 ANRPLVISILAGVSLQRIQKGFPDHA-IIRAMPNTPATVGAGMTAIAANKMVEPDQLAKA 145
Query: 475 SQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
+F AVG EVPE MDA+T +SGSGPAYV ++IE+LADGGV GLPR +A +LA QT
Sbjct: 146 KAIFSAVGNVVEVPENLMDAVTGVSGSGPAYVALMIEALADGGVLAGLPRAIAQKLALQT 205
Query: 295 TLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 119
LG+A ++K T +HPA +KD VTSP G+T G LEK GFRSAII AV AA R + +
Sbjct: 206 VLGTAELIKETEEHPAQIKDKVTSPGGTTIAGVAVLEKMGFRSAIIEAVRAAYRRSQELG 265
Query: 118 KQ 113
K+
Sbjct: 266 KK 267
>UniRef50_UPI00015C417B Cluster: pyrroline-5-carboxylate reductase;
n=1; Streptococcus gordonii str. Challis substr.
CH1|Rep: pyrroline-5-carboxylate reductase -
Streptococcus gordonii str. Challis substr. CH1
Length = 268
Score = 166 bits (404), Expect = 4e-40
Identities = 84/178 (47%), Positives = 115/178 (64%), Gaps = 1/178 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L +S+A G+T+ +E PS R IR+MPNTP +V EG +F+ +A D L +L
Sbjct: 90 LLVSMAAGLTLELLEKLTPSHHRWIRIMPNTPVVVGEGVISFALSQQANQTDEDLLQELL 149
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
+ G + E Q+DA TAL+G GPA+VY+ IE+LAD GVR GL RD++L LA QT LG+
Sbjct: 150 SSAGLLVRLEEKQLDAATALAGCGPAFVYLFIEALADAGVRAGLSRDISLELANQTLLGA 209
Query: 283 AAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 113
A + + +G HPA LKD+V SPAGST G LE+N FR ++ AV AA + K + K+
Sbjct: 210 AKLSQVSGQHPAQLKDHVCSPAGSTIAGVASLEENAFRGTVMDAVQAAYKKTKELGKK 267
>UniRef50_A5N0V3 Cluster: ProC2; n=1; Clostridium kluyveri DSM
555|Rep: ProC2 - Clostridium kluyveri DSM 555
Length = 283
Score = 166 bits (404), Expect = 4e-40
Identities = 89/180 (49%), Positives = 118/180 (65%), Gaps = 2/180 (1%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
IS+ GI + +E +LP E V+RVMPNTP LV GA+ + G A+ E A+L +F+A
Sbjct: 104 ISIIGGINTSLIEKHLP-EIPVVRVMPNTPMLVNIGASGVAPGKNASKEHAKLVYGMFEA 162
Query: 457 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 278
+G V E +D+ITA+SG GPAYVYM+IE++ADGGV GLPR++A LAAQT +G A
Sbjct: 163 LGVSYLVEEKYIDSITAISGCGPAYVYMMIEAMADGGVELGLPREMAQTLAAQTVMGGAK 222
Query: 277 MV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIV-KKQLND 104
M+ TG+HP LKD V SP GST G LE+ FR I+ A+ A R + V KK+ N+
Sbjct: 223 MILDTGEHPGKLKDKVCSPGGSTIAGVRALERGAFRGTIMNAIEAGKVRMEEVGKKEENN 282
>UniRef50_A0WB61 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Geobacter lovleyi SZ|Rep: Pyrroline-5-carboxylate
reductase - Geobacter lovleyi SZ
Length = 273
Score = 166 bits (404), Expect = 4e-40
Identities = 86/186 (46%), Positives = 121/186 (65%), Gaps = 1/186 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L ++N +A+ +L +S+ GI+ +E +L + RV+R MPNTPALV+ GA A G +
Sbjct: 81 LTALENTITAQ-QLVLSIMAGISTTIIEESLQNGVRVVRAMPNTPALVQAGATAICGGRR 139
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
A D L +LF VGT +V E QMDA+T +SGSGPAYV+ IE+L+D GV+ GLPRD
Sbjct: 140 AGEADLALAKELFSLVGTVYQVGERQMDAVTGVSGSGPAYVFSFIEALSDAGVKNGLPRD 199
Query: 322 LALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+A LA QT LGSA ++ ++ +HPA+L+D V+SP G+T + LE ++ AV A
Sbjct: 200 VATGLAVQTVLGSAQLLQQSNEHPAVLRDRVSSPGGTTIAALHTLENGRLHGLLMDAVDA 259
Query: 145 AVDRCK 128
AV R K
Sbjct: 260 AVKRSK 265
>UniRef50_Q7UTG7 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Pirellula sp.|Rep: Pyrroline-5-carboxylate reductase -
Rhodopirellula baltica
Length = 276
Score = 165 bits (401), Expect = 1e-39
Identities = 85/174 (48%), Positives = 116/174 (66%), Gaps = 1/174 (0%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
KL +S+A GI + + + + RV+RVMPNTP+LV EGA+ F + +D QL +
Sbjct: 101 KLIVSIAAGIGLDKLIDGVGHD-RVVRVMPNTPSLVGEGASGFCVSGGVSDDDVQLIETM 159
Query: 466 FKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
+VG +V E QM+ +T +SGSGPAYV+++IE+LADGGV GLPR AL+LA QT LG
Sbjct: 160 LNSVGIAAQVTEPQMNGVTGVSGSGPAYVFLIIEALADGGVAAGLPRATALQLATQTVLG 219
Query: 286 SAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
+A MV+ TG+HP LKDNV SP G+T LE+N R A+I AV A+ +R +
Sbjct: 220 AAKMVRETGEHPGFLKDNVCSPGGTTIAAMSVLEQNAVRGAMIQAVQASANRSR 273
>UniRef50_A7SC14 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 274
Score = 165 bits (401), Expect = 1e-39
Identities = 89/191 (46%), Positives = 122/191 (63%), Gaps = 1/191 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
+KEI L + ++ L +SVA GI +++ RVIR+MPN P VK+GAAAFS G K
Sbjct: 85 MKEIDKLITERH-LVVSVAAGIPLSSFSK--VGSIRVIRLMPNLPCSVKQGAAAFSCGEK 141
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
AT EDA L QL G EV E +D + ++GSG A+VY++IE++ADG V+ GLPR
Sbjct: 142 ATREDADLVHQLISTTGFVAEVKEPLIDTVCGVAGSGSAFVYVVIEAMADGAVKAGLPRV 201
Query: 322 LALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
LA + A Q LG+A VK +G HPA LKD SP G+T +G Y LE+ G R+A I AV++
Sbjct: 202 LANQFATQAVLGAATYVKESGKHPAQLKDETCSPGGTTIDGIYQLERGGVRAAFIDAVTS 261
Query: 145 AVDRCKIVKKQ 113
A + + + K+
Sbjct: 262 AASKAQELGKK 272
>UniRef50_Q00XH4 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Ostreococcus|Rep: Pyrroline-5-carboxylate reductase -
Ostreococcus tauri
Length = 282
Score = 164 bits (399), Expect = 2e-39
Identities = 83/176 (47%), Positives = 116/176 (65%), Gaps = 5/176 (2%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEAR----VIRVMPNTPALVKEGAAAFSRGTKATAEDAQL 479
K+F+SVA G+T+ +E + + ++RVMPNTP LV A+ +G+ + E
Sbjct: 100 KVFVSVAAGVTLEAMEGVWTTHDQKPPAIVRVMPNTPCLVGAAASGICKGSTCSEESLHR 159
Query: 478 TSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
L VG C + E QM A+T +SGSGPAYV++LIE++ADGGVR GLPRD+AL LAAQ
Sbjct: 160 ALALMSTVGVCKVIMESQMSALTGVSGSGPAYVFVLIEAMADGGVRAGLPRDVALELAAQ 219
Query: 298 TTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
T G++ MV +TG+HP +LKD V SP G+T + LE+ G R+A++ AV AA +R
Sbjct: 220 TFYGASKMVLETGEHPGVLKDKVCSPGGTTIAAVHALEQAGVRAAMMNAVLAAANR 275
>UniRef50_UPI0000D556D2 Cluster: PREDICTED: similar to CG6009-PA;
n=1; Tribolium castaneum|Rep: PREDICTED: similar to
CG6009-PA - Tribolium castaneum
Length = 309
Score = 161 bits (392), Expect = 1e-38
Identities = 80/181 (44%), Positives = 114/181 (62%), Gaps = 3/181 (1%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLP--SEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
NKLF+S+ GIT+ +E +RVIRVMPNTP +V EG A+ G T ED +
Sbjct: 129 NKLFVSILAGITLRELEEKTKVFQGSRVIRVMPNTPVVVGEGYTAYCPGQNVTEEDLSII 188
Query: 475 SQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
+ + G+C +PE ++A+ A+S SGPA+VY+ IE+L+DGGVR GL R+++ ++AAQT
Sbjct: 189 KSILEVTGSCQLLPEKMINAVGAISSSGPAFVYLFIEALSDGGVRMGLHREMSTKIAAQT 248
Query: 295 TLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 119
+G+A MV +T H LKD V S G+T G + LEK G R +++ AV AA R +
Sbjct: 249 VMGAAKMVLETSKHMGTLKDEVCSAGGTTIAGVHELEKGGVRGSVMNAVEAAAKRADELA 308
Query: 118 K 116
K
Sbjct: 309 K 309
>UniRef50_Q8RA68 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Thermoanaerobacter|Rep: Pyrroline-5-carboxylate
reductase - Thermoanaerobacter tengcongensis
Length = 264
Score = 161 bits (390), Expect = 2e-38
Identities = 87/189 (46%), Positives = 120/189 (63%), Gaps = 1/189 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
LKEI+ + + K+ I++A GITI V+ L +++R +PNTPAL+ EG A + +
Sbjct: 78 LKEIREKVT-EEKIIITIAPGITIDHVKKLL-GRGKIVRTIPNTPALIGEGITAVTYSEE 135
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
ED +L ++F G E+ E +D A+S PA+VYM IE+LADGGV GLPRD
Sbjct: 136 VKEEDKELVRKIFSTCGEIVEIEEKLIDVAMAVSSCSPAFVYMFIEALADGGVLLGLPRD 195
Query: 322 LALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+A +LA++ G+ +MV KTG HP LKD VTSP G+T EG LEK+G RSA+I AV A
Sbjct: 196 VAYKLASKAVSGAGSMVFKTGFHPGQLKDMVTSPGGTTIEGIRVLEKSGMRSAVIEAVIA 255
Query: 145 AVDRCKIVK 119
A + K +K
Sbjct: 256 AYQKAKGLK 264
>UniRef50_Q9X8G1 Cluster: Pyrroline-5-carboxylate reductase; n=11;
Actinomycetales|Rep: Pyrroline-5-carboxylate reductase -
Streptomyces coelicolor
Length = 284
Score = 160 bits (388), Expect = 4e-38
Identities = 83/175 (47%), Positives = 111/175 (63%), Gaps = 1/175 (0%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
++L IS A G+ + E L V+RVM NTPALV E + S GT ATA T +
Sbjct: 102 DRLVISGAAGVPTSFFEERLAPGTPVVRVMTNTPALVDEAMSVISAGTHATAAHLTHTEE 161
Query: 469 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
+F AVG VPE Q DA TALSGSGPAY + L+E++ D G+ GLPRD A L Q+ +
Sbjct: 162 IFGAVGKTLRVPESQQDACTALSGSGPAYFFYLVEAMTDAGILLGLPRDKAHDLIVQSAI 221
Query: 289 GSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
G+A M++ +G+HP L++NVTSPAG+T LE +G R+A+I A+ AA DR +
Sbjct: 222 GAAKMLRDSGEHPVKLRENVTSPAGTTINAIRELENHGVRAALIAALEAARDRSR 276
>UniRef50_Q8KG91 Cluster: Pyrroline-5-carboxylate reductase; n=10;
Chlorobiaceae|Rep: Pyrroline-5-carboxylate reductase -
Chlorobium tepidum
Length = 266
Score = 159 bits (387), Expect = 5e-38
Identities = 84/177 (47%), Positives = 111/177 (62%), Gaps = 1/177 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L +SVA GI+ +ESN P RV+RVMPNTPA V EG A +G ATA+D + ++F
Sbjct: 90 LIVSVAAGISTGFIESNCPEGTRVVRVMPNTPAFVGEGMTALCKGMHATADDLLVAERIF 149
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
A+G + E MDA TA+SGSGPAY++ +I+SLA+GG CGL R+ A LAAQT LG+
Sbjct: 150 NAIGKTAIIEESGMDAATAVSGSGPAYMFRIIDSLAEGGEACGLDRETAQLLAAQTMLGA 209
Query: 283 AAMVKTG-DHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 116
A MV +G P L VT+P G+T G +++ R A+I V AA R K + K
Sbjct: 210 AKMVLSGHKSPEELVREVTTPGGTTEAGLKAMDERDLRGALIDTVRAAAARSKELMK 266
>UniRef50_A7RN43 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 276
Score = 159 bits (387), Expect = 5e-38
Identities = 85/184 (46%), Positives = 121/184 (65%), Gaps = 2/184 (1%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
++ + S+A G+T+ ++ +LP R+IR+M NTP +EG A + G A ED +
Sbjct: 90 RDHIVSSIAAGVTLEWLQKSLPGRTRLIRMMLNTPVQFREGVTAMTFGKFAREEDYKDIH 149
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
+L +VG C EV E MD +TAL+G GPAY+Y+ IE++ADG VR GL R+ A++LAA+T
Sbjct: 150 ELMSSVGYCFEVDEDLMDVMTALTGGGPAYLYLAIEAMADGAVRAGLNREQAMKLAAKTA 209
Query: 292 LGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIV-K 119
G+A MV ++G HP LKD V S GST G + LE++GFR A++ AV+AA R K V K
Sbjct: 210 SGAARMVLESGLHPGELKDQVCSAGGSTIAGIFALEESGFRGALMKAVAAASLRAKEVGK 269
Query: 118 KQLN 107
+LN
Sbjct: 270 GELN 273
>UniRef50_Q27722 Cluster: Pyrroline carboxylate reductase; n=8;
Plasmodium|Rep: Pyrroline carboxylate reductase -
Plasmodium falciparum
Length = 209
Score = 158 bits (384), Expect = 1e-37
Identities = 79/179 (44%), Positives = 106/179 (59%), Gaps = 1/179 (0%)
Frame = -3
Query: 661 PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQ 482
P +KL IS+ G+ I +E + SE +++ VMPNTP LV EG+ + + D +
Sbjct: 26 PYLSSKLLISICGGLNIGKLEEMVGSENKIVWVMPNTPCLVGEGSFIYCSNKNVNSTDKK 85
Query: 481 LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAA 302
+ +F + G E+ E MD TA+SG GPAYVY+ IESL D GV+ GL R+L+ L
Sbjct: 86 YVNDIFNSCGIIHEIKEKDMDIATAISGCGPAYVYLFIESLIDAGVKNGLSRELSKNLVL 145
Query: 301 QTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
QT GS MVK D P LKDN+ SP G TA G Y LEKN F+ ++ AV AA ++ K
Sbjct: 146 QTIKGSVEMVKKSDQPVQQLKDNIVSPGGITAVGLYSLEKNSFKYTVMNAVEAACEKSK 204
>UniRef50_Q97R93 Cluster: Pyrroline-5-carboxylate reductase; n=13;
Streptococcus|Rep: Pyrroline-5-carboxylate reductase -
Streptococcus pneumoniae
Length = 265
Score = 158 bits (383), Expect = 2e-37
Identities = 79/184 (42%), Positives = 118/184 (64%), Gaps = 1/184 (0%)
Frame = -3
Query: 664 LPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDA 485
L ++ L IS+A G+T+ + S +PS+ R+IR+MPNTPA + +G +++ AED+
Sbjct: 82 LEKRESLLLISMAAGLTLEKLASLIPSQHRIIRMMPNTPASIGQGVISYALSPNCRAEDS 141
Query: 484 QLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 305
+L QL G E+ E +DA T L+G GPA+VY+ IE+LAD GV+ GLPR++AL++A
Sbjct: 142 ELFYQLLAKAGLLVELGESLIDAATGLAGCGPAFVYLFIEALADAGVQTGLPREIALKMA 201
Query: 304 AQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
AQT +G+ +V ++ HP +LKD V SP GST G LE + FR ++ AV A R +
Sbjct: 202 AQTVVGAGQLVLESQQHPGVLKDQVCSPGGSTIAGVASLEAHAFRGTVMDAVHQAYKRTQ 261
Query: 127 IVKK 116
+ K
Sbjct: 262 ELGK 265
>UniRef50_Q97E64 Cluster: Pyrroline-5-carboxylate reductase; n=10;
Clostridium|Rep: Pyrroline-5-carboxylate reductase -
Clostridium acetobutylicum
Length = 270
Score = 157 bits (381), Expect = 3e-37
Identities = 78/192 (40%), Positives = 124/192 (64%), Gaps = 2/192 (1%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLP-SEARVIRVMPNTPALVKEGAAAFSRGT 506
+ EIK+L ++ + +++A G++I S RV+R MPNTPALV E A S
Sbjct: 80 ISEIKDLVQ-QSVIIVAIAAGVSIEKTRIMFKNSNIRVVRAMPNTPALVGEAMTAISPCE 138
Query: 505 KATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
+ + + +++F++ G C+ V E M+A+T +SGS PAYVYM +E++AD V G+ R
Sbjct: 139 EIDKGELKNVTEIFESFGKCEVVDEALMNAVTGVSGSSPAYVYMFVEAMADAAVLNGMTR 198
Query: 325 DLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
+ A + AAQ+ LG+A M+ +TG+HP LKD+V SP+G+T E Y LEK+GFR+++I AV
Sbjct: 199 EKAYKFAAQSVLGAAKMILETGEHPGKLKDDVCSPSGTTIEAVYALEKSGFRASVIAAVD 258
Query: 148 AAVDRCKIVKKQ 113
A + + K++ +
Sbjct: 259 ACIKKSKLMSSK 270
>UniRef50_A6BFA0 Cluster: Putative uncharacterized protein; n=1;
Dorea longicatena DSM 13814|Rep: Putative
uncharacterized protein - Dorea longicatena DSM 13814
Length = 173
Score = 156 bits (378), Expect = 6e-37
Identities = 73/171 (42%), Positives = 109/171 (63%), Gaps = 1/171 (0%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
+S+ G+T+ +++ + R++R++PNTPA+V EGA A T ++ + ++
Sbjct: 1 MSIVAGVTVERLQNMIDGTPRILRLLPNTPAMVFEGAFALCSDNDLTEDELEAAKSIYST 60
Query: 457 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 278
+G + +PE+ +DA LSG GPAYV M IE +ADGGV+ GLPR A RLAAQT LG+A
Sbjct: 61 IGVVEMIPEHLLDAACGLSGGGPAYVAMFIEPMADGGVKQGLPRATAYRLAAQTCLGTAK 120
Query: 277 MV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
M+ + G HP LKD VTSP G+T EG LEK G R A+I ++ + ++ +
Sbjct: 121 MILEKGIHPGELKDMVTSPGGTTIEGCEALEKAGMRGAVIECINVSTEKSR 171
>UniRef50_A0LDU8 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Magnetococcus sp. MC-1|Rep: Pyrroline-5-carboxylate
reductase - Magnetococcus sp. (strain MC-1)
Length = 270
Score = 156 bits (378), Expect = 6e-37
Identities = 81/178 (45%), Positives = 114/178 (64%), Gaps = 2/178 (1%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
A + +S+A G+ + T+ + LP+ +IR MPNTPALV +G AE
Sbjct: 89 APTAVVLSIAAGVDLTTMAAALPAGQPIIRAMPNTPALVGQGMTVLCPNGHVDAEQLAQA 148
Query: 475 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
+L ++VG V E MD +TALSGSGPAY++++ E+L+DGGV CGLPR LA +LA Q
Sbjct: 149 QRLLESVGQVAVVKQESLMDGVTALSGSGPAYLFLIAEALSDGGVACGLPRALADQLAVQ 208
Query: 298 TTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
T LGSA +++ +G+HP +LK+ VTSP G+T G LE+ G R A++ AV AA +R K
Sbjct: 209 TLLGSATLLRESGEHPGVLKNRVTSPGGTTIAGLGVLERQGVRGALMAAVEAAWNRSK 266
>UniRef50_Q6NP47 Cluster: Pyrroline-5-carboxylate reductase; n=10;
Endopterygota|Rep: Pyrroline-5-carboxylate reductase -
Drosophila melanogaster (Fruit fly)
Length = 341
Score = 156 bits (378), Expect = 6e-37
Identities = 81/186 (43%), Positives = 117/186 (62%), Gaps = 7/186 (3%)
Frame = -3
Query: 670 KNLPSAKN--KLFISVAMGITIATVESNLP----SEARVIRVMPNTPALVKEGAAAFSRG 509
K++PSAK+ KL +SV G ++ T+E SE +VIR MPNT V EG ++
Sbjct: 149 KHVPSAKDASKLVVSVLAGTSLETLEEAFSFMGSSELKVIRTMPNTSMQVGEGCTVYTGN 208
Query: 508 TKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
+ + D + + A+G +VPE +DA+T ++G GPA+VY +IE+LADGGV+ G+P
Sbjct: 209 ARVSHHDLEKIHLMLNALGLAQQVPESMIDAVTGVAGCGPAFVYTIIEALADGGVKQGVP 268
Query: 328 RDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
R +AL+ AAQT LG+A ++ TG HPA+L+D V SP G+T G + LEK RS +I AV
Sbjct: 269 RQMALQFAAQTLLGAAKTVLLTGKHPAVLRDEVCSPGGATIVGVHELEKGNLRSTLINAV 328
Query: 151 SAAVDR 134
+ R
Sbjct: 329 EKSSQR 334
>UniRef50_Q1F0K7 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=1; Clostridium oremlandii OhILAs|Rep: Delta
1-pyrroline-5-carboxylate reductase - Clostridium
oremlandii OhILAs
Length = 273
Score = 155 bits (375), Expect = 1e-36
Identities = 79/191 (41%), Positives = 113/191 (59%), Gaps = 1/191 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+EI + + K+++ +S+A GIT + ++IR+MPN P V EG A S
Sbjct: 80 LREISSYVT-KDQIIVSLAAGITTEDMGEYFKEPMKIIRIMPNVPVSVGEGMIALSSNGN 138
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
T E+ QL +VG D++ E +DA+T +SG PA++ M +E+LADG VR G+PRD
Sbjct: 139 VTGEEVDFVVQLLSSVGKVDQIDESLIDAVTTISGCSPAFIAMFVEALADGSVRKGMPRD 198
Query: 322 LALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
A AAQT +G+ M+ + G HP LKD V+SP G T EG Y LEK GFR+ +I V A
Sbjct: 199 KAYLYAAQTLIGTGKMILEKGLHPGELKDMVSSPGGVTIEGVYELEKRGFRNMLIEVVEA 258
Query: 145 AVDRCKIVKKQ 113
+ K +K +
Sbjct: 259 CERKTKSMKSK 269
>UniRef50_Q0AYD4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Syntrophomonas wolfei subsp. wolfei str. Goettingen|Rep:
Pyrroline-5-carboxylate reductase - Syntrophomonas
wolfei subsp. wolfei (strain Goettingen)
Length = 268
Score = 153 bits (372), Expect = 3e-36
Identities = 78/171 (45%), Positives = 111/171 (64%), Gaps = 1/171 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L IS+A GI + E+ + V+RVMPNTP LV +G +A S G AT ++ QL +++F
Sbjct: 91 LLISLAAGIKTGSYENEIGLHLPVVRVMPNTPCLVGQGVSAISPGRYATDKNLQLVAKMF 150
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
+ +GTC V E MDAITA+SGSGPAYV++++ESL + ++ GL LA +L T GS
Sbjct: 151 EQLGTCVMVEEKHMDAITAISGSGPAYVFLVVESLMNAALQVGLDLKLARQLVVNTVKGS 210
Query: 283 AAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
M+ ++G+HPA+L++ V SP G+T G LE+NG R A AV A +R
Sbjct: 211 MEMMEQSGEHPAILREQVCSPGGTTIAGIRQLEENGLRRAFFQAVEKAYER 261
>UniRef50_UPI00015B577C Cluster: PREDICTED: similar to GA19292-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA19292-PA - Nasonia vitripennis
Length = 282
Score = 153 bits (371), Expect = 4e-36
Identities = 81/188 (43%), Positives = 116/188 (61%), Gaps = 4/188 (2%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNL---PSEARVIRVMPNTPALVKEGAAAFS 515
AL+ K KLF+SV +GI + T++ L S ++IR MP+TP +V EG +
Sbjct: 85 ALRTCKPPHHTTGKLFVSVIVGIPLDTLDEKLRAVDSFPKIIRSMPSTPMMVGEGITVYC 144
Query: 514 RGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCG 335
+ E+ + LF +G C+++PE M++ LSGSGPAY YM+IE+LADG V+ G
Sbjct: 145 -SLRTNEEEECAINYLFSQLGLCEKIPESLMNSAGGLSGSGPAYAYMIIEALADGAVKKG 203
Query: 334 LPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 158
+PR A R AAQ +G+ MV +TG HP +LKD V SP GST G + +E G R+A++
Sbjct: 204 IPRASATRFAAQVLVGAGKMVLETGKHPGLLKDEVCSPGGSTITGVHAMETGGVRAAMMN 263
Query: 157 AVSAAVDR 134
AV AAV++
Sbjct: 264 AVEAAVNK 271
>UniRef50_Q4SMN2 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Clupeocephala|Rep: Pyrroline-5-carboxylate reductase -
Tetraodon nigroviridis (Green puffer)
Length = 333
Score = 153 bits (371), Expect = 4e-36
Identities = 76/173 (43%), Positives = 111/173 (64%), Gaps = 1/173 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
+ +SVA G+T+AT+E LP VIR+MPN P LV+EGA F+RG+ A ED L L
Sbjct: 158 VIVSVAAGVTLATLEELLPENTVVIRMMPNLPCLVQEGALLFARGSHAKPEDGALLRSLL 217
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
G +E PE +D T +SGSG A+VY+ E+LA+G V+ G+P LA +A+QT LG+
Sbjct: 218 HHCGLVEEGPELWIDIHTGMSGSGVAFVYLFAEALAEGAVKMGMPSALAHSIASQTVLGA 277
Query: 283 AAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
+++ +G HPA L+ V +P G+T G + LE+ G R+A + AV +A +R +
Sbjct: 278 GRVLRDSGKHPAQLRAEVCTPGGTTIYGLHTLEQGGVRAATMSAVESATERAR 330
>UniRef50_Q3AAH4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Carboxydothermus hydrogenoformans Z-2901|Rep:
Pyrroline-5-carboxylate reductase - Carboxydothermus
hydrogenoformans (strain Z-2901 / DSM 6008)
Length = 259
Score = 152 bits (369), Expect = 8e-36
Identities = 81/187 (43%), Positives = 117/187 (62%), Gaps = 2/187 (1%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATV-ESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
+KEI P K+ +SVA G+++ + E +P E V+RVMPNTPAL+ +G A + +
Sbjct: 77 IKEIS--PGLSGKILVSVAAGVSLKKIAEWGVPGECEVVRVMPNTPALIGQGFIAITP-S 133
Query: 505 KATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
KA A L +++F ++G + E D ITAL+GSGPAY+Y++ E+L DG VR GLPR
Sbjct: 134 KANA----LLAEIFDSLGEVVFLEEKYFDQITALAGSGPAYIYLVAEALIDGAVRLGLPR 189
Query: 325 DLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
D+A QT +G+ AM+K T +HP +L+D V +P G+TA G Y LEK G R +
Sbjct: 190 DVARSAVVQTLIGAGAMLKETQEHPGILRDAVVTPGGTTAAGLYQLEKQGIRGMFADCLE 249
Query: 148 AAVDRCK 128
+A +R K
Sbjct: 250 SAYERAK 256
>UniRef50_Q4QFY6 Cluster: Pyrroline-5-carboxylate reductase; n=7;
Trypanosomatidae|Rep: Pyrroline-5-carboxylate reductase
- Leishmania major
Length = 272
Score = 151 bits (366), Expect = 2e-35
Identities = 77/196 (39%), Positives = 121/196 (61%), Gaps = 1/196 (0%)
Frame = -3
Query: 688 PALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRG 509
P L+ IK +KL +S+A G+ IAT+E++ P + +V+RVMPN P+ V EG + S
Sbjct: 78 PVLETIKE-KITPSKLVVSMAAGVPIATIENHCPPKTKVVRVMPNIPSYVGEGVTSISGN 136
Query: 508 TKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
+ T +D + +LF A+G V E + + ++GS PAYV+M +E+L+DG VR G+P
Sbjct: 137 SAVTPDDEAVVMKLFSAIGKSYLVAESAIHGVVGVAGSSPAYVFMFMEALSDGAVRGGIP 196
Query: 328 RDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
R + +AAQ LG+A M++ +G P+ LKD V SP G+T E LEK G RS+II A+
Sbjct: 197 RAQSYEMAAQAVLGAAKMLQDSGKTPSALKDMVCSPGGTTIEAVRFLEKGGMRSSIIEAM 256
Query: 151 SAAVDRCKIVKKQLND 104
+++ K ++ ++
Sbjct: 257 IQCMEKSKEFERMYSE 272
>UniRef50_A5Z6I9 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 273
Score = 151 bits (365), Expect = 2e-35
Identities = 79/179 (44%), Positives = 108/179 (60%), Gaps = 2/179 (1%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAE-DAQLTS 473
+K+ IS+A G TI ++ L + R++R MPNTPA++ EG E + + +
Sbjct: 96 DKVIISLAPGFTITQLKEKLKA-GRIVRSMPNTPAMIGEGMTGVCFDENEFDENEIDVIN 154
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
++F+A G +V E M+++ SGS PAYV+M IE+LAD V+CGLPR A AQT
Sbjct: 155 KIFEATGKAKKVDEKLMNSVVCASGSSPAYVFMFIEALADSAVKCGLPRKDAYEFVAQTV 214
Query: 292 LGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 119
LGSA M++TG HP LKD V SP G+T G LEKNGFR AI A A ++C +K
Sbjct: 215 LGSAKLMLETGKHPGELKDMVCSPGGTTIAGVAELEKNGFRKAIFEATDACFNKCNNIK 273
>UniRef50_UPI000051A719 Cluster: PREDICTED: similar to Pyrroline
5-carboyxlate reductase CG6009-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Pyrroline
5-carboyxlate reductase CG6009-PA - Apis mellifera
Length = 281
Score = 149 bits (361), Expect = 7e-35
Identities = 81/188 (43%), Positives = 116/188 (61%), Gaps = 6/188 (3%)
Frame = -3
Query: 685 ALKEIKNLPSAKNK--LFISVAMGITIATVESNLPSEA---RVIRVMPNTPALVKEGAAA 521
ALK I+ ++K LF+SV +G+T+ + + L S R+IR MPNTP +V EG
Sbjct: 84 ALKGIRETMTSKASHILFVSVLVGVTLDCLANKLKSIVTYPRIIRCMPNTPMMVGEGITV 143
Query: 520 FSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVR 341
+ T +D + +LF +G + VPE M+AI LSGSGPAY Y++IE+LADG V+
Sbjct: 144 YC-SMNTTNQDETIIEKLFSYIGVIENVPESLMNAIGGLSGSGPAYAYLVIEALADGAVK 202
Query: 340 CGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAI 164
G+PR +A + AAQ +G+ MV +TG HP LKD V SP G+T G + +E R+++
Sbjct: 203 MGVPRPMATKFAAQVLVGAGKMVLETGRHPGQLKDEVCSPGGTTITGVHAMECGQVRASM 262
Query: 163 IGAVSAAV 140
+ AV AAV
Sbjct: 263 MNAVEAAV 270
>UniRef50_Q6NJK7 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Corynebacterium diphtheriae|Rep: Pyrroline-5-carboxylate
reductase - Corynebacterium diphtheriae
Length = 270
Score = 147 bits (357), Expect = 2e-34
Identities = 76/187 (40%), Positives = 119/187 (63%), Gaps = 2/187 (1%)
Frame = -3
Query: 688 PALKEIKNL-PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSR 512
P ++EI ++ + + +S+A G+T A +E +L + + VIRVMPNTP LV +G + +
Sbjct: 79 PVVEEIADVVDNNTSTTIVSMAAGVTNAMIEESLAAGSPVIRVMPNTPMLVGKGMSVVAP 138
Query: 511 GTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGL 332
G A + +QL +AVG+ + + E MDA+ ALSGS PAY+++++E+L D GV GL
Sbjct: 139 GRYADEDTVASLTQLLEAVGSVEVIEESSMDAVVALSGSSPAYLFLMVEALIDAGVFLGL 198
Query: 331 PRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGA 155
PRD A LA + G+A M+ +TG+ PA+L+ NV+SP G+T E++G R+A+ A
Sbjct: 199 PRDKAKNLAVSSFAGAATMLEQTGEEPAVLRANVSSPGGTTIAAIREFEESGLRAAVYRA 258
Query: 154 VSAAVDR 134
+AA R
Sbjct: 259 ATAAATR 265
>UniRef50_A6G2U4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Plesiocystis pacifica SIR-1|Rep: Pyrroline-5-carboxylate
reductase - Plesiocystis pacifica SIR-1
Length = 267
Score = 147 bits (357), Expect = 2e-34
Identities = 79/173 (45%), Positives = 108/173 (62%), Gaps = 5/173 (2%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRG----TKATAEDAQL 479
KL IS+A G+T++++ LP A +IR MPNTP L+ EG R T A+ E L
Sbjct: 88 KLLISIAAGVTLSSLAQWLPQTA-LIRAMPNTPCLIGEGMTVLGRRDAGPTAASDEQLAL 146
Query: 478 TSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
++F +VG EV MDA+T+L+GSGPA+VY+++E++ADGGV GLPRD+A+ +AAQ
Sbjct: 147 AKRIFDSVGVTAEVEPKLMDAVTSLNGSGPAFVYVMLEAMADGGVMMGLPRDVAVTIAAQ 206
Query: 298 TTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
G+A MV D HPA LKD VT+PAG T G +E RS + + A
Sbjct: 207 VFRGAAGMVLDTDLHPAALKDQVTTPAGCTIAGILTMEDGRIRSVLARTIQEA 259
>UniRef50_A3DD78 Cluster: Pyrroline-5-carboxylate reductase
precursor; n=2; Clostridium|Rep: Pyrroline-5-carboxylate
reductase precursor - Clostridium thermocellum (strain
ATCC 27405 / DSM 1237)
Length = 271
Score = 147 bits (357), Expect = 2e-34
Identities = 78/179 (43%), Positives = 107/179 (59%), Gaps = 1/179 (0%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
NK+ +SVA+GI I + L + IR MPNTPALV EG ++A+ +
Sbjct: 90 NKILVSVAVGIPIKFYKEMLGENIKFIRTMPNTPALVGEGMTLMCCDKNVDEKEAEQVKK 149
Query: 469 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
+F+ G + + E M +TA++ S PAYV+M IE++AD V G+PR+LA +L+AQ L
Sbjct: 150 IFECFGKVEFLEEKLMSEVTAVTSSSPAYVFMFIEAMADAAVLSGIPRNLAYKLSAQAVL 209
Query: 289 GSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 116
G+A MV +TG HP LKD V SPAG+T E LEKN FR AII A+S + + K
Sbjct: 210 GAAKMVLETGKHPGELKDQVCSPAGTTIEAVRSLEKNRFRYAIIEAMSECTKKALEIGK 268
>UniRef50_Q8S488 Cluster: Delta-1-pyrroline-5-carboxylate reductase;
n=1; Phytophthora nicotianae|Rep:
Delta-1-pyrroline-5-carboxylate reductase - Phytophthora
nicotianae (Buckeye rot agent)
Length = 314
Score = 145 bits (352), Expect = 9e-34
Identities = 73/173 (42%), Positives = 109/173 (63%), Gaps = 2/173 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L ISV G +I ++ +L ++ +IR MPNTPA++ EG +++ + T+ +LT Q+
Sbjct: 126 LVISVVAGQSIKQLQQHLGQDSHIIRTMPNTPAMIGEGTTVWAQSAEVTSVQHELTKQIL 185
Query: 463 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
+ G V E +D TALSGSGPAY +++ E++ D GV G R +A +L QT LG
Sbjct: 186 GSFGVEVFVDDENALDMATALSGSGPAYFFLVAEAMIDTGVHMGFSRPVATKLVQQTMLG 245
Query: 286 SAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRC 131
SA +++ D HP L++N+TSP G+TA G Y EKNGFR+ I ++ AA +RC
Sbjct: 246 SALYMQSEDVHPVELRNNITSPGGTTAAGLYRAEKNGFRAVIADSIWAAYERC 298
>UniRef50_P0A9L9 Cluster: Pyrroline-5-carboxylate reductase; n=65;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Shigella flexneri
Length = 269
Score = 145 bits (351), Expect = 1e-33
Identities = 74/192 (38%), Positives = 114/192 (59%), Gaps = 3/192 (1%)
Frame = -3
Query: 682 LKEIKNLPSAKNK--LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRG 509
+K + + S+ NK L +S+A G+T+ + L + ++IR MPNTPALV G + +
Sbjct: 77 IKVLSEITSSLNKDSLVVSIAAGVTLDQLARALGHDRKIIRAMPNTPALVNAGMTSVTPN 136
Query: 508 TKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
T ED +F+ G + + E + + +SGS PAYV+M IE++AD V G+P
Sbjct: 137 ALVTPEDTADVLNIFRCFGEAEVIAEPMIHPVVGVSGSSPAYVFMFIEAMADAAVLGGMP 196
Query: 328 RDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
R A + AAQ +GSA MV +TG+HP LKD V SP G+T E LE+ GFR+A+I A+
Sbjct: 197 RAQAYKFAAQAVMGSAKMVLETGEHPGALKDMVCSPGGTTIEAVRVLEEKGFRAAVIEAM 256
Query: 151 SAAVDRCKIVKK 116
+ +++ + + K
Sbjct: 257 TKCMEKSEKLSK 268
>UniRef50_Q9P7Y7 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Schizosaccharomyces pombe|Rep: Pyrroline-5-carboxylate
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 282
Score = 145 bits (351), Expect = 1e-33
Identities = 73/180 (40%), Positives = 106/180 (58%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L K + K KL +S+ G TI++++S L RVIR+MPNT + ++E + G
Sbjct: 94 LNSPKMKEALKGKLILSILAGKTISSLQSMLDESTRVIRIMPNTASRIRESMSVICPGPN 153
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
AT ED + +F +G ++PE +DA TA+ GSGPA+V +IE++ DGGV G+P
Sbjct: 154 ATEEDIKFAEWVFNGIGRSMKLPEKLIDAATAVCGSGPAFVATMIEAMTDGGVMMGIPFP 213
Query: 322 LALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
A LAAQT +G+ MV G HPAM++++V++PAG T G LE RS I + A
Sbjct: 214 QAQELAAQTMVGTGRMVLQGQHPAMIRNDVSTPAGCTISGLLALEDGKIRSTIARGIEQA 273
>UniRef50_Q86ER8 Cluster: Clone ZZD150 mRNA sequence; n=3;
Schistosoma japonicum|Rep: Clone ZZD150 mRNA sequence -
Schistosoma japonicum (Blood fluke)
Length = 313
Score = 144 bits (350), Expect = 2e-33
Identities = 81/210 (38%), Positives = 117/210 (55%), Gaps = 2/210 (0%)
Frame = -3
Query: 739 VERSEXXXXXXXXXXXVPALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVM 560
VE+S+ +P LK + N NKL IS+A GIT+ ++ +P+ R+IR+M
Sbjct: 104 VEKSDIIFACVKPHILLPVLKGLWN--RLDNKLLISIAAGITLDQIQKAVPTSTRIIRIM 161
Query: 559 PNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDE-VPEYQMDAITALSGSGPAY 383
PNTP V G A ++ + T D QL S L ++ E +PE +A A+SGS PA+
Sbjct: 162 PNTPCQVGVGTAVYAHTSTVTEHDIQLISALCSSIFPVFEAIPESLFNAAVAMSGSSPAF 221
Query: 382 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAE 206
+YM+ E++ D GV GLPR A +L T LGSA M++ D + LK+NV SP G+T
Sbjct: 222 IYMVAEAITDAGVLLGLPRATAQKLIVNTILGSAVMMQKSDKNTTELKNNVCSPGGTTIH 281
Query: 205 GTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 116
G Y LEK R+ ++ AV R + + K
Sbjct: 282 GVYALEKGNLRATLMDAVQKVCARGEELSK 311
>UniRef50_Q0SF18 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Actinomycetales|Rep: Pyrroline-5-carboxylate reductase -
Rhodococcus sp. (strain RHA1)
Length = 271
Score = 142 bits (345), Expect = 6e-33
Identities = 79/184 (42%), Positives = 109/184 (59%), Gaps = 3/184 (1%)
Frame = -3
Query: 685 ALKEIKN--LPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSR 512
AL E+ L + +L +S+A GI A E+ LP+ V+RVMPNTP LV EG + +
Sbjct: 76 ALTEVSKVELDGEREQLLVSLAAGIPTAFYETRLPAGFPVVRVMPNTPMLVGEGVSVLAP 135
Query: 511 GTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGL 332
G E +L + +VG VPE Q+DA+TA+SGSGPAY +++ E++ D GV GL
Sbjct: 136 GRHVKKEHLELVRGVLSSVGKVVVVPESQIDAVTAVSGSGPAYFFLVAEAMIDAGVGLGL 195
Query: 331 PRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGA 155
R A L QT +GSAAM+ ++G+ L+ VTSP G+TA LE NG R+A A
Sbjct: 196 TRATASELVVQTMVGSAAMLDRSGESATELRAAVTSPGGTTAAAIRRLEGNGLRTAFFDA 255
Query: 154 VSAA 143
+ AA
Sbjct: 256 LEAA 259
>UniRef50_Q5KFS4 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Basidiomycota|Rep: Pyrroline-5-carboxylate reductase -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 313
Score = 140 bits (340), Expect = 2e-32
Identities = 75/173 (43%), Positives = 105/173 (60%), Gaps = 1/173 (0%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+ KL IS+ G+TI+ ++S +P RV+R MPNTP + EG + + A + L
Sbjct: 133 EGKLLISICAGVTISQLKSWVPESTRVVRAMPNTPCKIGEGMTIVTPLSDALSRT--LIL 190
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
+F + G C + E DA TAL+GSGPA+V +++E++ADGGV GLPR AL LAAQT
Sbjct: 191 NIFTSCGRCRFLDEKHFDACTALAGSGPAFVALVLEAMADGGVMMGLPRSEALELAAQTM 250
Query: 292 LGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVD 137
G+ M ++TG HPA LKD+VT+P G T G LE RS + A+ A +
Sbjct: 251 QGTGRMALQTGLHPAQLKDSVTTPGGCTIAGLLTLEDGRVRSTMARAIQVATN 303
>UniRef50_Q8F631 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Leptospira|Rep: Pyrroline-5-carboxylate reductase -
Leptospira interrogans
Length = 273
Score = 140 bits (339), Expect = 3e-32
Identities = 82/180 (45%), Positives = 110/180 (61%), Gaps = 7/180 (3%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
K ISVA GI I T+ NLP+ + V+RVMPN P LV EGA F E + S++
Sbjct: 94 KKIISVAAGIHIDTILKNLPTGSNVVRVMPNLPLLVSEGAIGFF----GDEELYETVSEI 149
Query: 466 FKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
F+ +G ++ E MDA+T LSGSGPAYV+ I++LA+GGV GL AL L+ QT +
Sbjct: 150 FQPLGHSVKLGSETLMDAVTGLSGSGPAYVFKFIQALAEGGVLSGLGYQEALDLSIQTVI 209
Query: 289 GSAAMVK------TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
GSA +++ HP + K+ VTSP G+T G LEKNGF +A++ AV AA +R K
Sbjct: 210 GSAQLLRKEREKDPTTHPEVWKNKVTSPGGTTIAGLVELEKNGFSNAVLEAVKAAANRSK 269
>UniRef50_A0K0A3 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Arthrobacter|Rep: Pyrroline-5-carboxylate reductase -
Arthrobacter sp. (strain FB24)
Length = 277
Score = 140 bits (339), Expect = 3e-32
Identities = 75/179 (41%), Positives = 104/179 (58%), Gaps = 1/179 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
+ +SVA ++IA +E+ LP+ VIR MPNTPA + G + S GT +AE QL +
Sbjct: 98 IVVSVAAAVSIAQLEAALPAGQPVIRTMPNTPAKLGRGVVSVSPGTNCSAEQLQLAKNIL 157
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
K GT EVPE Q+DA++A+SGSGPAYV+ L E++A GV GL +L+L LA +T G
Sbjct: 158 KGAGTVVEVPEEQVDALSAISGSGPAYVFYLAEAMAAAGVELGLDPELSLLLARETVAGG 217
Query: 283 AAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 110
M+ + G P L+ VTSP G+T ++ G + I AA R + KQL
Sbjct: 218 GLMLAEPGADPTALRKAVTSPNGTTERAIATFDERGLPAIIADGARAAAARAAEITKQL 276
>UniRef50_Q2ZZM3 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=4; Lactobacillales|Rep: Delta
1-pyrroline-5-carboxylate reductase - Streptococcus suis
89/1591
Length = 261
Score = 140 bits (338), Expect = 4e-32
Identities = 81/189 (42%), Positives = 117/189 (61%), Gaps = 1/189 (0%)
Frame = -3
Query: 676 EIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKAT 497
+I PSA ++IS+A G+ + ++ + + ++ ++IR+MPNTP + +G +S
Sbjct: 80 QISQNPSA---IWISMAAGVPLDSLAAFVSAD-KLIRIMPNTPVAIGQGMTTYSL---VN 132
Query: 496 AEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLA 317
E A L Q+ + G +VPE +DA TA++G GPA+VY +IE+L D GV+ GL A
Sbjct: 133 QELAPLLEQILEKSGKVQQVPESLIDAATAIAGCGPAFVYQMIEALTDAGVQNGLTAQDA 192
Query: 316 LRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAV 140
LAAQT G+A MV T D HPA L+ VTSP GST G LEK GFR AII AV+AA+
Sbjct: 193 KVLAAQTLAGTAQMVLTSDKHPAQLRQEVTSPGGSTIAGVVALEKEGFRYAIIRAVAAAL 252
Query: 139 DRCKIVKKQ 113
+ + + K+
Sbjct: 253 KKTRKLGKK 261
>UniRef50_Q53H96 Cluster: Pyrroline-5-carboxylate reductase-like
protein; n=27; Euteleostomi|Rep: Pyrroline-5-carboxylate
reductase-like protein - Homo sapiens (Human)
Length = 276
Score = 140 bits (338), Expect = 4e-32
Identities = 68/152 (44%), Positives = 98/152 (64%), Gaps = 1/152 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
+ +SVA G++++T+E LP RV+RV+PN P +V+EGA +RG + + L L
Sbjct: 109 ILVSVAAGVSLSTLEELLPPNTRVLRVLPNLPCVVQEGAIVMARGRHVGSSETNLLQHLL 168
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
+A G C+EVPE +D T LSGSG A+V E+LA+G V+ G+P LA R+AAQT LG+
Sbjct: 169 EACGRCEEVPEAYVDIHTGLSGSGVAFVCAFSEALAEGAVKMGMPSSLAHRIAAQTLLGT 228
Query: 283 AAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHL 191
A M + G HPA L+ +V +P G+T G + L
Sbjct: 229 AKMLLHEGQHPAQLRSDVCTPGGTTIYGLHAL 260
>UniRef50_Q11141 Cluster: Pyrroline-5-carboxylate reductase; n=18;
Corynebacterineae|Rep: Pyrroline-5-carboxylate reductase
- Mycobacterium tuberculosis
Length = 295
Score = 139 bits (337), Expect = 6e-32
Identities = 84/189 (44%), Positives = 109/189 (57%), Gaps = 18/189 (9%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
++F++V GITIA ES LP+ V+R MPN ALV G A ++G T + + S L
Sbjct: 98 QVFVTVVAGITIAYFESKLPAGTPVVRAMPNAAALVGAGVTALAKGRFVTPQQLEEVSAL 157
Query: 466 FKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
F AVG VPE Q+DA+TA+SGSGPAY ++L+E+L D GV GL R +A LAAQT G
Sbjct: 158 FDAVGGVLTVPESQLDAVTAVSGSGPAYFFLLVEALVDAGVGVGLSRQVATDLAAQTMAG 217
Query: 286 SAAMV----------KTGD--------HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAII 161
SAAM+ G+ + L+ VTSP G+TA LE+ GFR A+
Sbjct: 218 SAAMLLERMEQDQGGANGELMGLRVDLTASRLRAAVTSPGGTTAAALRELERGGFRMAVD 277
Query: 160 GAVSAAVDR 134
AV AA R
Sbjct: 278 AAVQAAKSR 286
>UniRef50_Q6AL13 Cluster: Related to pyrroline-5-carboxylate
reductase; n=1; Desulfotalea psychrophila|Rep: Related
to pyrroline-5-carboxylate reductase - Desulfotalea
psychrophila
Length = 272
Score = 138 bits (333), Expect = 2e-31
Identities = 71/181 (39%), Positives = 112/181 (61%), Gaps = 2/181 (1%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLP-SEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
++ L I++A G+ I++ L ++IRVMPNTPALV + A+A + + E+
Sbjct: 90 EDHLLITIAAGLPISSYVKTLALPRLKIIRVMPNTPALVGQSASALTASPYVSQEELDKV 149
Query: 475 SQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
+F +GT + E +DA+T LSGSGPAYV+ IE+L D GV GL R ++ LA QT
Sbjct: 150 QNIFNQIGTTTVLEECHLDAVTGLSGSGPAYVFSFIEALIDAGVAEGLNRQVSTNLALQT 209
Query: 295 TLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 119
GS +++ G+HPA+ + V+SP G+T + LE++GF++ I+ AV+AA ++ K +
Sbjct: 210 VAGSVELLRQNGEHPAVERARVSSPGGTTIAASKILERSGFQAIIMDAVAAATEKSKELG 269
Query: 118 K 116
K
Sbjct: 270 K 270
>UniRef50_P0C1E4 Cluster: Pyrroline-5-carboxylate reductase; n=5;
Corynebacterium|Rep: Pyrroline-5-carboxylate reductase -
Corynebacterium glutamicum (Brevibacterium flavum)
Length = 270
Score = 138 bits (333), Expect = 2e-31
Identities = 72/183 (39%), Positives = 109/183 (59%), Gaps = 1/183 (0%)
Frame = -3
Query: 658 SAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQL 479
++ + +S+A GI+IA +E + + V+RVMPNTP LV +G + ++G AE +
Sbjct: 88 NSAQSVVVSMAAGISIAAMEESASAGLPVVRVMPNTPMLVGKGMSTVTKGRYVDAEQLEQ 147
Query: 478 TSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
L VG EV E +DA+TA+SGS PAY++++ E+L + GV GLPR A +LA
Sbjct: 148 VKDLLSTVGDVLEVAESDIDAVTAMSGSSPAYLFLVTEALIEAGVNLGLPRATAKKLAVA 207
Query: 298 TTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIV 122
+ G+A M+K TG P+ L+ V+SPAG+T LE++G R A A A DR + +
Sbjct: 208 SFEGAATMMKETGKEPSELRAGVSSPAGTTVAAIRELEESGIRGAFYRAAQACADRSEEL 267
Query: 121 KKQ 113
K+
Sbjct: 268 GKR 270
>UniRef50_Q67QH2 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Symbiobacterium thermophilum|Rep:
Pyrroline-5-carboxylate reductase - Symbiobacterium
thermophilum
Length = 284
Score = 137 bits (332), Expect = 2e-31
Identities = 71/174 (40%), Positives = 103/174 (59%), Gaps = 1/174 (0%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
++ +S+A GI + +E + V+R MPNT V E A A G AT E +L +++
Sbjct: 96 QIVLSLAAGIATSFIEERVADGVMVVRAMPNTSCQVGESATAVCLGRAATPEAMRLVTEM 155
Query: 466 FKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
+VG VPE QMDA+T LSGSGPAYVY ++E++ + G GL ++A L QT G
Sbjct: 156 LASVGQVYTVPEEQMDAVTGLSGSGPAYVYYIVEAMIEAGEAVGLAPEVARALTLQTLKG 215
Query: 286 SA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
+A + TG PA+L++ VTSP G+TA G L + GF A+I A+ A +R +
Sbjct: 216 AALTLATTGADPAVLREQVTSPGGTTAAGLQVLREAGFAQALISAIVRATERSR 269
>UniRef50_Q64E79 Cluster: Pyrroline-5-carboxylate reductase; n=1;
uncultured archaeon GZfos13E1|Rep:
Pyrroline-5-carboxylate reductase - uncultured archaeon
GZfos13E1
Length = 295
Score = 136 bits (330), Expect = 4e-31
Identities = 74/184 (40%), Positives = 109/184 (59%), Gaps = 4/184 (2%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNL-PSEAR---VIRVMPNTPALVKEGAAAFSRGTKATAEDA 485
++K+ ISVA G+ A ++ L ++AR VIRVMPN A V+E A +G A D
Sbjct: 107 EDKILISVAAGVPTAAIDGYLGEAKARGRKVIRVMPNIGACVREAVCAICKGKYADEADE 166
Query: 484 QLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 305
++ ++ A+GT V E MD IT LSGSG A+V +I+++ADG V GLPR+L+L +A
Sbjct: 167 EIAKEILSAIGTVHSVNEGDMDVITGLSGSGIAFVATVIDAMADGAVYEGLPRELSLTIA 226
Query: 304 AQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKI 125
AQT +G+A M+ G P+ + SP G+T G Y +E ++A++ AV A R
Sbjct: 227 AQTAIGAAKMILEGKQPSEIVTMTASPGGTTIRGIYTMESRNVKAAMMEAVIEATRRATE 286
Query: 124 VKKQ 113
+ KQ
Sbjct: 287 ISKQ 290
>UniRef50_P14383 Cluster: Pyrroline-5-carboxylate reductase 1; n=5;
Bacillus|Rep: Pyrroline-5-carboxylate reductase 1 -
Bacillus subtilis
Length = 297
Score = 136 bits (329), Expect = 5e-31
Identities = 73/189 (38%), Positives = 111/189 (58%), Gaps = 1/189 (0%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
++L +SV GIT + +E +L +E V+RVMPNT +++ A A + G + + +L
Sbjct: 105 HQLILSVLAGITTSFIEQSLLNEQPVVRVMPNTSSMIGASATAIALGKYVSEDLKKLAEA 164
Query: 469 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
L +G + E QMD T ++GSGPAY Y L+E + G GL + L+ + AQT L
Sbjct: 165 LLGCMGEVYTIQENQMDIFTGIAGSGPAYFYYLMEFIEKTGEEAGLDKQLSRSIGAQTLL 224
Query: 289 GSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 113
G+A M ++TG+HP +L+DN+TSP G+TA G L+K+G AI A+ A R K + +
Sbjct: 225 GAAKMLMETGEHPEILRDNITSPNGTTAAGLQALKKSGGGEAISQAIKHAAKRSKEISED 284
Query: 112 LND*TA*LS 86
+ A LS
Sbjct: 285 IEKTAAPLS 293
>UniRef50_Q5KXH0 Cluster: Pyrroline-5-carboxylate reductase; n=13;
Bacillaceae|Rep: Pyrroline-5-carboxylate reductase -
Geobacillus kaustophilus
Length = 299
Score = 136 bits (328), Expect = 7e-31
Identities = 73/173 (42%), Positives = 100/173 (57%), Gaps = 1/173 (0%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
++L +S+ GIT T+E V+R MPNT A V A A + G A E ++ Q
Sbjct: 112 HQLILSLLAGITTETIERLAGRNIPVVRAMPNTSAAVGLSATAIAGGRFAAKEHLEVAKQ 171
Query: 469 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
LF+ VG VPE + A+T LSGSGPAYVY L+E++ GL RD+A RL QT +
Sbjct: 172 LFETVGIVAVVPEKDLHAVTGLSGSGPAYVYYLVEAMEKAAADIGLERDVAKRLILQTII 231
Query: 289 GSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
G+A M+K D HP++L+ VTSP G+T G LE+ F+ A+I + A R
Sbjct: 232 GAAEMLKASDKHPSVLRREVTSPGGTTEAGIGVLEQYRFQEAVIACIRRATAR 284
>UniRef50_Q8U084 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Thermococcaceae|Rep: Pyrroline-5-carboxylate reductase -
Pyrococcus furiosus
Length = 261
Score = 135 bits (326), Expect = 1e-30
Identities = 75/193 (38%), Positives = 119/193 (61%), Gaps = 1/193 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+EIK ++K+ IS+A GI I ++ + A+ +R MPN LVKE A++
Sbjct: 73 LEEIKE--EVESKIVISLAAGIPIKLLKRF--ANAKFVRAMPNIAVLVKESFTAYAT-ED 127
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
+ E+ + ++F++ G + E MDAIT LSGSGPAYV + +E++ GG+R GLPRD
Sbjct: 128 LSEEEIRTVEKIFESFGKYIRIDEEYMDAITGLSGSGPAYVSVFLEAMIYGGLRVGLPRD 187
Query: 322 LALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+A AAQT LG+A ++ + HPA ++D V +P G+T +G + LE+ R+ I+ A+ A
Sbjct: 188 IAKLAAAQTLLGTAKLLLNFEGHPAEIRDMVITPGGTTIDGIFELEEGKIRTTIMKAIDA 247
Query: 145 AVDRCKIVKKQLN 107
A + KI+ +L+
Sbjct: 248 ATKKSKILSTRLS 260
>UniRef50_A4J3P9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Desulfotomaculum reducens MI-1|Rep:
Pyrroline-5-carboxylate reductase - Desulfotomaculum
reducens MI-1
Length = 281
Score = 134 bits (323), Expect = 3e-30
Identities = 70/185 (37%), Positives = 109/185 (58%), Gaps = 1/185 (0%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
AL E+++ + +N++ ISV G+ + +E +L ++ VIR MPNT + E A S G
Sbjct: 82 ALDELRD-STQENQIIISVLAGVPTSLIEDSLNTQIAVIRAMPNTSCAILESATGLSAGR 140
Query: 505 KATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
T +L ++F +G V E+ +DA+T LSGSGPAY+Y L+E++ G G+PR
Sbjct: 141 FTTPNQLKLAEEIFCMMGEVVVVEEHLLDAVTGLSGSGPAYIYYLVEAMEKAGETAGIPR 200
Query: 325 DLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
+LA L +T LG+A M ++TG++P L+ VTSP G+T G L K F++ + A+
Sbjct: 201 ELARPLVLKTLLGAAKMLMETGENPEELRRQVTSPNGTTMAGINELNKGDFQNTLRKAIL 260
Query: 148 AAVDR 134
A R
Sbjct: 261 KATRR 265
>UniRef50_Q233Y5 Cluster: Pyrroline-5-carboxylate reductase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
Pyrroline-5-carboxylate reductase family protein -
Tetrahymena thermophila SB210
Length = 336
Score = 133 bits (322), Expect = 4e-30
Identities = 79/183 (43%), Positives = 106/183 (57%), Gaps = 1/183 (0%)
Frame = -3
Query: 679 KEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
KEI + ++KL IS+A G + T L R+IRVMPNTP +V GA+AFS G +
Sbjct: 145 KEIAEV--CQDKLIISIAAGTKLETFYK-LFGHKRIIRVMPNTPMMVGIGASAFSMGDQC 201
Query: 499 TAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 320
D + +F VG +V E MDA+TA+SGSGPAYV+ I++LAD GV+ GL ++
Sbjct: 202 KETDRDICLSIFSPVGKIHQVEECHMDAVTAVSGSGPAYVFQFIKALADAGVQQGLQPEV 261
Query: 319 ALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
+L LA QT LG+A MV P L VTSP G+T +EK F+ + V AA
Sbjct: 262 SLDLATQTVLGAAMMVSLNQGTPEELTKAVTSPNGTTYAALCCMEKLQFKETVYKFVEAA 321
Query: 142 VDR 134
+R
Sbjct: 322 TNR 324
>UniRef50_A2EU21 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Trichomonas vaginalis G3|Rep: Pyrroline-5-carboxylate
reductase - Trichomonas vaginalis G3
Length = 269
Score = 132 bits (320), Expect = 7e-30
Identities = 76/188 (40%), Positives = 105/188 (55%), Gaps = 5/188 (2%)
Frame = -3
Query: 682 LKEIKNLPSAKNK----LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFS 515
LKEI N ++ K + +++A G TI+ +S L + +IR+MPNTP LV EG
Sbjct: 77 LKEIANTVKSERKKRELVILTIAAGKTISFYQSIL-GDIPIIRLMPNTPCLVSEGMTLLV 135
Query: 514 RGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCG 335
R KAT E + F G E+PE QMDA +++G G + M IE+LADG V G
Sbjct: 136 RSPKATDEHVEKVKNFFSKSGLIQEIPESQMDAAGSVAGCGTGFFCMFIEALADGAVMEG 195
Query: 334 LPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 158
+PR A + AAQ G+A +V ++G HP LKD + SP GST G LE FR+ ++
Sbjct: 196 IPRPDAYKYAAQALKGTAELVLQSGKHPGALKDEICSPGGSTIAGVKALEDGKFRATVME 255
Query: 157 AVSAAVDR 134
AV + R
Sbjct: 256 AVLQSTKR 263
>UniRef50_P22008 Cluster: Pyrroline-5-carboxylate reductase; n=21;
Gammaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Pseudomonas aeruginosa
Length = 273
Score = 132 bits (319), Expect = 9e-30
Identities = 73/187 (39%), Positives = 112/187 (59%), Gaps = 3/187 (1%)
Frame = -3
Query: 661 PSAK-NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDA 485
P+ K +L +S+A GI A++E+ L V+R MPNTPAL+++GA+ + +A
Sbjct: 85 PALKPEQLIVSIAAGIPCASLEAWLGQPRPVVRCMPNTPALLRQGASGLYANAQVSAAQC 144
Query: 484 QLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRL 308
+ QL AVG + E Q+DA+TA+SGSGPAY ++L++++ D G + GL R+ A RL
Sbjct: 145 EQAGQLLSAVGIALWLDDEAQIDAVTAVSGSGPAYFFLLMQAMTDAGEKLGLSRETASRL 204
Query: 307 AAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRC 131
QT LG+A M + + PA L+ VTSP G+T + NGF + + A++AA R
Sbjct: 205 TLQTALGAAQMALSSEVEPAELRRRVTSPNGTTEAAIKSFQANGFEALVEQALNAASQRS 264
Query: 130 KIVKKQL 110
+ +QL
Sbjct: 265 AELAEQL 271
>UniRef50_Q48P99 Cluster: Pyrroline-5-carboxylate reductase; n=6;
Gammaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Pseudomonas syringae pv. phaseolicola
(strain 1448A / Race 6)
Length = 284
Score = 132 bits (318), Expect = 1e-29
Identities = 75/182 (41%), Positives = 108/182 (59%), Gaps = 2/182 (1%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
N+L +SVA GIT A++ L + V+R MPNTP+L+++GA+ K TAE + Q
Sbjct: 102 NQLIVSVAAGITCASLTQWLGDQP-VVRCMPNTPSLLRQGASGLYATDKVTAEQREQAEQ 160
Query: 469 LFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
L AVG V E MDA+TA+SGSGPAY ++++E++ GV+ GLP D+A +L QT
Sbjct: 161 LLSAVGVAVWVEQEKHMDAVTAVSGSGPAYFFLMMEAMTAAGVKLGLPEDIAKKLTLQTA 220
Query: 292 LGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 116
LGSA + D A L+ VTSP G+T + GF + + A++AA R + +
Sbjct: 221 LGSALIATGSDVGAGELRRRVTSPGGTTEAAIKAFQAGGFEALVETALTAADHRAAELAE 280
Query: 115 QL 110
QL
Sbjct: 281 QL 282
>UniRef50_Q0ICK3 Cluster: Pyrroline-5-carboxylate reductase; n=17;
Cyanobacteria|Rep: Pyrroline-5-carboxylate reductase -
Synechococcus sp. (strain CC9311)
Length = 294
Score = 131 bits (317), Expect = 2e-29
Identities = 69/174 (39%), Positives = 103/174 (59%), Gaps = 1/174 (0%)
Frame = -3
Query: 661 PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQ 482
P++ + L +SV G+ +A +++ P +R +PNTP LV +G + G + Q
Sbjct: 113 PASGSSLLLSVLAGVPLARLQALFPGRI-CVRAVPNTPCLVGQGLTGLAWGDGISDPQKQ 171
Query: 481 LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAA 302
F+ V E+PE ++DA AL+ SGPAYV ++ E++ADG V G+PR A LA
Sbjct: 172 QVRSFFEPVSEVLELPEERLDAFLALTSSGPAYVALIAEAMADGAVAMGMPRSQAHHLAH 231
Query: 301 QTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
+T G+AA+++ + HP LKD V SP G+T HLEK+G RSA+I A+ AA
Sbjct: 232 RTLAGTAALLQEQELHPGELKDMVASPGGTTMAALRHLEKSGLRSALIEAIVAA 285
>UniRef50_A7GVZ9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Campylobacter curvus 525.92|Rep: Pyrroline-5-carboxylate
reductase - Campylobacter curvus 525.92
Length = 303
Score = 131 bits (316), Expect = 2e-29
Identities = 74/176 (42%), Positives = 101/176 (57%), Gaps = 4/176 (2%)
Frame = -3
Query: 658 SAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQL 479
+A +FI+VA +I V L ++A+V R MPN P+L+ EG A + + TA+D
Sbjct: 122 NASQPIFITVAPNFSIQMVREVLGADAKVARTMPNMPSLIGEGVTAVNFSSNFTADDRAA 181
Query: 478 TSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
++ G E+ E + TA++GS PAY++M IE+LADG V GL R+ A + +
Sbjct: 182 VMKILSYFGKSYELAEDKFAVFTAIAGSLPAYIFMFIEALADGAVLEGLGREKAYAIVCE 241
Query: 298 TTLGSAAM----VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
GSA M +K G HPA LKD V SP G+T E LE FR+AII AVSAA
Sbjct: 242 AVAGSAKMATAALKEGKHPARLKDEVCSPGGTTIEAVRVLENAKFRAAIIEAVSAA 297
>UniRef50_Q02WW5 Cluster: Pyrroline-5-carboxylate reductase; n=12;
Streptococcaceae|Rep: Pyrroline-5-carboxylate reductase
- Lactococcus lactis subsp. cremoris (strain SK11)
Length = 263
Score = 130 bits (314), Expect = 4e-29
Identities = 66/181 (36%), Positives = 109/181 (60%), Gaps = 2/181 (1%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEAR-VIRVMPNTPALVKEGAAAFSRGTKATAEDAQL 479
+K+K IS+A G+T++ ++ SE + +IRVMPN A + + +A + ++
Sbjct: 83 SKDKTLISIAAGLTLSDLKHLADSENQPIIRVMPNINAQIGQSTSAIVKNEFVDDSADEI 142
Query: 478 TSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
++FKAVG+ E+ E A++GS PA++YM I+++A GV GLP+D A + ++
Sbjct: 143 AQEIFKAVGSVHEIAEKDFSTFAAIAGSSPAFIYMFIDAMARAGVLRGLPKDQATAIVSE 202
Query: 298 TTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIV 122
T SA M +K+G++P L D V+SP G+T G LE+N F +I A+SA ++R K +
Sbjct: 203 TVKASAEMLLKSGENPWSLVDKVSSPGGTTVAGVVSLEQNHFGGTVIDAISATIEREKYL 262
Query: 121 K 119
K
Sbjct: 263 K 263
>UniRef50_Q836Y3 Cluster: Pyrroline-5-carboxylate reductase,
putative; n=1; Enterococcus faecalis|Rep:
Pyrroline-5-carboxylate reductase, putative -
Enterococcus faecalis (Streptococcus faecalis)
Length = 271
Score = 129 bits (311), Expect = 8e-29
Identities = 75/194 (38%), Positives = 106/194 (54%), Gaps = 3/194 (1%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVES--NLPSEARVIRVMPNTPALVKEGAAAFSR 512
AL E K K L +S+A G TIA + R++RVMPN AL+ GAAA
Sbjct: 77 ALLEAKEAILDKQPLIVSIAAGTTIAELYQLFETTQPLRLVRVMPNMNALIGAGAAAVCG 136
Query: 511 GTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGL 332
A+ ED Q LF+AVG E+ E TA++GS PAY ++ I+S+A V+ G+
Sbjct: 137 NAFASPEDIQTVLSLFRAVGQAWELEEQYFSIFTAIAGSTPAYAFLFIDSIARAAVKNGM 196
Query: 331 PRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGA 155
++LAL +A Q LGSA + + ++P L D V+SP G+T G LE N F S +I
Sbjct: 197 NKELALEIATQAVLGSAQTLANSTENPWTLIDQVSSPGGTTVAGIVELENNAFISTVIKG 256
Query: 154 VSAAVDRCKIVKKQ 113
+ A + R + + KQ
Sbjct: 257 IEATILRDQELAKQ 270
>UniRef50_P54552 Cluster: Pyrroline-5-carboxylate reductase 2; n=4;
Bacillus|Rep: Pyrroline-5-carboxylate reductase 2 -
Bacillus subtilis
Length = 278
Score = 129 bits (311), Expect = 8e-29
Identities = 68/184 (36%), Positives = 102/184 (55%), Gaps = 1/184 (0%)
Frame = -3
Query: 661 PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQ 482
P K++L ISV G+TI T++ + VIRVMPNT A +++ A FS T+A+ D
Sbjct: 85 PYIKDQLVISVLAGLTIETIQHYFGRKLAVIRVMPNTSAAIRKSATGFSVSTEASKNDII 144
Query: 481 LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAA 302
L + +G V E +DA+TA++GSGPAYVY IE++ + GL ++ A L
Sbjct: 145 AAKALLETIGDATLVEERHLDAVTAIAGSGPAYVYRYIEAMEKAAQKVGLDKETAKALIL 204
Query: 301 QTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKI 125
QT G+ M +++G P L+ +TSP G+T G L+ + F AII + R
Sbjct: 205 QTMAGATDMLLQSGKQPEKLRKEITSPGGTTEAGLRALQDSRFEEAIIHCIEETAKRSAE 264
Query: 124 VKKQ 113
+K+Q
Sbjct: 265 IKEQ 268
>UniRef50_Q312A7 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Desulfovibrio|Rep: Pyrroline-5-carboxylate reductase -
Desulfovibrio desulfuricans (strain G20)
Length = 267
Score = 128 bits (310), Expect = 1e-28
Identities = 67/173 (38%), Positives = 102/173 (58%), Gaps = 2/173 (1%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA-TAEDAQLTSQ 470
K+ +S+A G+++ + S A V+RVMPNTPA+V G A +AE A
Sbjct: 89 KVLVSIAAGVSLEAMRSAAQGAAPVVRVMPNTPAMVGRGIYGMCLDDPALSAEAATAVRN 148
Query: 469 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
LF A+G +PE + +A TA++G GPAYV+ ++E++ + V G R A + +
Sbjct: 149 LFAAIGKVIVLPEQKFEAFTAVAGCGPAYVFHMMEAVIEAAVTVGFTRQQATEMVTELFS 208
Query: 289 GSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
GS A+ +TG HP++L++ VTSPAG+T GT HL++ R II AV AA ++
Sbjct: 209 GSCALAEQTGIHPSLLREMVTSPAGTTIAGTNHLDRTAVRGHIIDAVLAAYEK 261
>UniRef50_Q6AAZ1 Cluster: Putative delta-1-pyrroline-5-carboxylate
reductase; n=1; Propionibacterium acnes|Rep: Putative
delta-1-pyrroline-5-carboxylate reductase -
Propionibacterium acnes
Length = 263
Score = 128 bits (309), Expect = 1e-28
Identities = 71/183 (38%), Positives = 107/183 (58%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+E+ A + + +S+A G+T T + + + +++RVMPNTP V +GA S
Sbjct: 80 LEEVSGALKA-DAVVVSIAAGVT--TEKLLMAWQGKIVRVMPNTPVRVGKGAFIVS-SAP 135
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
+ + A+ L ++VG VPE +A TA+SGSGPAYV+++ E++ D V G+PRD
Sbjct: 136 GSEDAAKKVGDLLESVGVVVTVPEELHNAATAVSGSGPAYVFLVAEAMIDAAVALGVPRD 195
Query: 322 LALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
A +L T GSA ++ G+HPA+L+ VTSP G+TA LE G RS A++A
Sbjct: 196 QASQLTVATLAGSAELLAGGEHPAVLRSKVTSPGGTTAAAVAALEAGGVRSVFADAMTAC 255
Query: 142 VDR 134
DR
Sbjct: 256 RDR 258
>UniRef50_P54893 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Deinococci|Rep: Pyrroline-5-carboxylate reductase -
Thermus thermophilus (strain HB27 / ATCC BAA-163 / DSM
7039)
Length = 261
Score = 128 bits (308), Expect = 2e-28
Identities = 70/170 (41%), Positives = 98/170 (57%), Gaps = 1/170 (0%)
Frame = -3
Query: 640 FISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKAT-AEDAQLTSQLF 464
+IS+ GI+ + + L + RV+R MPN ++ E + A + +A AED LF
Sbjct: 86 YISIMAGISTSVLARRLDNR-RVVRAMPNLAVVIGESSTALTALKEAREAEDLAFARALF 144
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
VG E+PE+ DA T +S S PAY+ ++ E+LAD GV+ G+PR LALRLAA +
Sbjct: 145 ATVGDVYEIPEHLFDAFTGMSASAPAYLAVVAEALADAGVKMGMPRALALRLAADALAAT 204
Query: 283 AAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
++K G HPA +KD V SP G+T G + LE R+A AV AA R
Sbjct: 205 GELLK-GRHPAQVKDEVASPGGTTIHGLHALEARAVRAAFYEAVEAATRR 253
>UniRef50_Q8EU76 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Oceanobacillus iheyensis|Rep: Pyrroline-5-carboxylate
reductase - Oceanobacillus iheyensis
Length = 270
Score = 127 bits (306), Expect = 3e-28
Identities = 63/172 (36%), Positives = 96/172 (55%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
+++ ISV G+T +E+ L E VIR MPNT AL+ A A ++G+ T E + Q
Sbjct: 91 DQMVISVIAGLTTERMEAILEKEIPVIRTMPNTSALIGYSATAIAKGSYVTDEQLAVAEQ 150
Query: 469 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
LF+ VG + E M +TA++GSGPA+ Y ++E++ V GL ++A +L AQT +
Sbjct: 151 LFQTVGMTTIIKEKDMHTVTAIAGSGPAFFYYMVEAMEQAAVEAGLDAEMASQLIAQTVI 210
Query: 289 GSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
G+ M++ P L+ N+TSP G+T G L F S + V A +R
Sbjct: 211 GAGKMLELSGDPITLRKNITSPGGTTEAGVQQLMSEDFASIVQSCVQRARER 262
>UniRef50_Q6CEN0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Yarrowia lipolytica|Rep: Pyrroline-5-carboxylate
reductase - Yarrowia lipolytica (Candida lipolytica)
Length = 299
Score = 126 bits (305), Expect = 4e-28
Identities = 71/180 (39%), Positives = 106/180 (58%), Gaps = 5/180 (2%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVES--NLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQL 479
+ K+ +S+ G TIA +ES + V+R M NTP+ + G S AT +++ +
Sbjct: 111 EGKVLVSLLAGKTIADIESYSGRCPKPLVVRAMTNTPSRIGAGMTVLSFPDNATVDESVV 170
Query: 478 T--SQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 305
S +F+ G C + E QMD TAL GS PA+ +++IE+LADG VR G+P + A + A
Sbjct: 171 NAVSWIFEQTGKCITLEEKQMDVSTALCGSSPAFCFLIIEALADGAVRMGMPYNTAFQCA 230
Query: 304 AQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
AQ+ LG+A M V++G HPA+LK V +P G+T G LE G RS++ AV + + K
Sbjct: 231 AQSMLGAAKMVVESGQHPAVLKSAVCTPGGTTIGGLLALEDKGVRSSVARAVEESTNIAK 290
>UniRef50_A2QIA2 Cluster: Catalytic activity: L-proline + NAD(P)(+)
<=> 1-pyrroline-5- carboxylate + NAD(P)H. precursor;
n=8; Pezizomycotina|Rep: Catalytic activity: L-proline +
NAD(P)(+) <=> 1-pyrroline-5- carboxylate + NAD(P)H.
precursor - Aspergillus niger
Length = 286
Score = 126 bits (305), Expect = 4e-28
Identities = 75/180 (41%), Positives = 102/180 (56%), Gaps = 7/180 (3%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSE----ARVIRVMPNTPALVKEGAAAFSRGTKATAEDA 485
K + +S+A GIT+ +++ L E A V+RVMPNTPALV EGA+ G + + ED
Sbjct: 96 KFPIVVSIAAGITLESLQKWLSVEGGKVAPVVRVMPNTPALVTEGASGAFAGVEVSKEDK 155
Query: 484 QLTSQLFKAVGTCDEVPEYQ--MDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 311
L L +V E + + +D +T LSGSGPAY + ++E L GL ++ A R
Sbjct: 156 GLVEALLGSVSRVTEWVDKEELLDVVTGLSGSGPAYFFAMVEHLVASATALGLTKEQATR 215
Query: 310 LAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
LAAQT LG+ M V++ D PA L+ NVTSP G+T EK F + AV AA DR
Sbjct: 216 LAAQTCLGAGKMLVESDDEPAQLRKNVTSPNGTTYAALQTFEKLNFADIVDQAVKAATDR 275
>UniRef50_Q6KZ51 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Picrophilus torridus|Rep: Pyrroline-5-carboxylate
reductase - Picrophilus torridus
Length = 257
Score = 126 bits (304), Expect = 6e-28
Identities = 70/191 (36%), Positives = 108/191 (56%), Gaps = 1/191 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L EIK+ + KNK+ +S GI I +ES ++ + R MPN P + + A +
Sbjct: 72 LNEIKD--NIKNKIIVSFLAGINIDYIESY--AKTSIFRAMPNLPIITGDAITAVAY-KN 126
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
A ++ +FK G C + E MDA+T LSGSGPA++ ++I+S+ G+R GLPRD
Sbjct: 127 ADENTIKIVDDIFKKTGECIFIDEKSMDAVTGLSGSGPAFISIMIDSMIVAGIRMGLPRD 186
Query: 322 LALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
A +L +T G+A M KTG P+ ++D V +PAG+ A G + +E R+ I AV A
Sbjct: 187 TARKLTLKTFEGTARLMEKTGLPPSEIRDRVMTPAGTAAAGVFEIENGNIRTTIARAVEA 246
Query: 145 AVDRCKIVKKQ 113
+ R +K++
Sbjct: 247 STKRSMELKRK 257
>UniRef50_Q831S6 Cluster: Pyrroline-5-carboxylate reductase,
putative; n=1; Enterococcus faecalis|Rep:
Pyrroline-5-carboxylate reductase, putative -
Enterococcus faecalis (Streptococcus faecalis)
Length = 260
Score = 124 bits (300), Expect = 2e-27
Identities = 72/185 (38%), Positives = 101/185 (54%), Gaps = 3/185 (1%)
Frame = -3
Query: 688 PALKEIKNLPSAKNK-LFISVAMGITIATVESNLPS-EARVIRVMPNTPALVKEGAAAFS 515
P L+E+ P N+ L ISVA G TI + L + EA+V+ +PNTP V +G +
Sbjct: 75 PVLQELA--PHFSNESLLISVATGHTIQEAQMALGNKEAKVVHAIPNTPVSVNQGVIGVA 132
Query: 514 RGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCG 335
+ L +L +G E+ E Q++ ++G PA+V + +E+L D V G
Sbjct: 133 LAPTIEGQTKDLAMELLATLGLVKEIREAQLETFGTVAGCSPAFVDIFMEALGDAAVLEG 192
Query: 334 LPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 158
LPRDL+ + AQ G+A + + T HP LKD VTSP GST G LEKNGFR A++
Sbjct: 193 LPRDLSYEIVAQMIKGTATLALDTKKHPGALKDEVTSPGGSTIRGVVALEKNGFRYAVMD 252
Query: 157 AVSAA 143
AV A
Sbjct: 253 AVQQA 257
>UniRef50_A3LST6 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=5; Saccharomycetales|Rep: Delta
1-pyrroline-5-carboxylate reductase - Pichia stipitis
(Yeast)
Length = 277
Score = 124 bits (300), Expect = 2e-27
Identities = 80/190 (42%), Positives = 107/190 (56%), Gaps = 2/190 (1%)
Frame = -3
Query: 676 EIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKAT 497
E+K+ + K +L IS+ G TI+ + P V +VM NTPA G A S +A
Sbjct: 92 EVKDSLTGK-QLLISLLAGTTISELTIFTPY---VAKVMTNTPARFGCGTAGISFSPEAE 147
Query: 496 AEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLA 317
A+ L +L VG ++PE MDA TAL GSGPA+ +++ESL DGGVR GLP ++A
Sbjct: 148 AKYEDLVLKLIGTVGEAFKIPEKNMDAATALIGSGPAFCLLMMESLIDGGVRMGLPFEVA 207
Query: 316 LRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAII-GAVSAA 143
AA+ G+A MV +TGDHPA LK V +P G+T G +E G R+ I G AA
Sbjct: 208 KLSAAKVMEGTARMVLETGDHPAALKSMVCTPGGTTIGGLLKMEDAGVRAGIARGVEEAA 267
Query: 142 VDRCKIVKKQ 113
V KK+
Sbjct: 268 VISASFAKKK 277
>UniRef50_Q8YCL9 Cluster: PYRROLINE-5-CARBOXYLATE REDUCTASE; n=11;
Alphaproteobacteria|Rep: PYRROLINE-5-CARBOXYLATE
REDUCTASE - Brucella melitensis
Length = 300
Score = 123 bits (297), Expect = 4e-27
Identities = 69/147 (46%), Positives = 91/147 (61%), Gaps = 3/147 (2%)
Frame = -3
Query: 640 FISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGA-AAFSRGTKATAEDAQLTSQLF 464
F+SVA GI +A ES+L + VIR MPNTPA + +G F + A +A +TS L
Sbjct: 122 FVSVAAGIPVALFESHLGKDVAVIRCMPNTPAAIGKGMLVTFKNANVSDANEAFVTS-LL 180
Query: 463 KAVGTCDEVPEYQ-MDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
K G V E MDA+TA+SGSGPAY++ IE+L D GV GLPR+ A LA QT +G
Sbjct: 181 KTSGKVASVDEEGLMDAVTAVSGSGPAYIFHFIEALTDAGVNLGLPRETAALLAMQTVMG 240
Query: 286 SAAMVKTG-DHPAMLKDNVTSPAGSTA 209
+ A+ D P+ L++ VTSP G+TA
Sbjct: 241 AGALADASTDSPSKLREQVTSPNGTTA 267
>UniRef50_Q83A21 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Coxiella burnetii|Rep: Pyrroline-5-carboxylate reductase
- Coxiella burnetii
Length = 274
Score = 123 bits (297), Expect = 4e-27
Identities = 69/193 (35%), Positives = 109/193 (56%), Gaps = 2/193 (1%)
Frame = -3
Query: 679 KEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
+E+K++ S L IS+A+G+T +E L +R++R MPNTP+ V+ GA
Sbjct: 81 EELKDILSETKILVISLAVGVTTPLIEKWLGKASRIVRAMPNTPSSVRAGATGLFANETV 140
Query: 499 TAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
+ L + +AVG V E Q++ I ALSGSGPAY+++++E+L + + GL ++
Sbjct: 141 DKDQKNLAESIMRAVGLVIWVSSEDQIEKIAALSGSGPAYIFLIMEALQEAAEQLGLTKE 200
Query: 322 LALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
A L QT LG+A M ++T L+ VTSP G+T + LE R I A++A
Sbjct: 201 TAELLTEQTVLGAARMALETEQSVVQLRQFVTSPGGTTEQAIKVLESGNLRELFIKALTA 260
Query: 145 AVDRCKIVKKQLN 107
AV+R K + K ++
Sbjct: 261 AVNRAKELSKTVD 273
>UniRef50_A5CND2 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Actinobacteria (class)|Rep: Pyrroline-5-carboxylate
reductase - Clavibacter michiganensis subsp.
michiganensis (strain NCPPB 382)
Length = 291
Score = 123 bits (297), Expect = 4e-27
Identities = 71/173 (41%), Positives = 95/173 (54%), Gaps = 1/173 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L ISVA G+TIAT ES LP+ V+R MPNTP+LV G + GT++ E L +F
Sbjct: 114 LVISVAAGVTIATFESLLPAHVAVLRSMPNTPSLVGRGVTGLAAGTRSGPEHLALARAVF 173
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
VG EVPE ++DA++ +SGSGPAYV++LIE L G D A L T G+
Sbjct: 174 ATVGDVVEVPEERIDALSTISGSGPAYVFLLIEELTRTAKAKGFSPDEARVLVQGTFRGA 233
Query: 283 AAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
++ +GD PA L+ VTSP G+T L+ A AA+ R +
Sbjct: 234 VELLAVSGDEPAELRRRVTSPNGTTERAVQVLQAADLSGLFDRATDAALARAR 286
>UniRef50_Q1GJ10 Cluster: Pyrroline-5-carboxylate reductase; n=24;
Alphaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Silicibacter sp. (strain TM1040)
Length = 271
Score = 122 bits (294), Expect = 9e-27
Identities = 79/186 (42%), Positives = 102/186 (54%), Gaps = 9/186 (4%)
Frame = -3
Query: 664 LPSAKN-----KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
LPSAK+ LFISVA G I+T E+ L ++R MPNTPA V G A
Sbjct: 79 LPSAKSYGGGGTLFISVAAGTPISTFETMLGESTPIVRAMPNTPAAVGRGITALIGNAHV 138
Query: 499 TAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
L +AVG + E QMDA+T +SGSGPAYV+ LIE+LA GV GLP
Sbjct: 139 DEAKMAQADALLQAVGQTVRLDDEGQMDAVTGVSGSGPAYVFHLIETLAAAGVAQGLPEP 198
Query: 322 LALRLAAQTTLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHL--EKNGFRSAIIGAV 152
LA++LA T G+ A+ + + P+ L+ NVTSP G+T L E+ GF + AV
Sbjct: 199 LAMQLAKATVAGAGALAEAAEEDPSALRVNVTSPNGTTQAALEVLMDEETGFPPLLQRAV 258
Query: 151 SAAVDR 134
+AA R
Sbjct: 259 AAAAKR 264
>UniRef50_A5WCA1 Cluster: Pyrroline-5-carboxylate reductase; n=5;
Moraxellaceae|Rep: Pyrroline-5-carboxylate reductase -
Psychrobacter sp. PRwf-1
Length = 282
Score = 122 bits (294), Expect = 9e-27
Identities = 69/183 (37%), Positives = 103/183 (56%), Gaps = 2/183 (1%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
+L ISVA G++ ++ L ++R MPNTPA++++GA + D QL + L
Sbjct: 100 QLVISVAAGLSTDSLSKMLSGYQNIVRAMPNTPAMIQKGATGLYANDSISETDKQLAATL 159
Query: 466 FKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
A G V E Q+ A+TA+SGS PAY + +IES+ + GV GL R A LA QT L
Sbjct: 160 MAASGLVSWVEQEEQLHAVTAVSGSAPAYFFYMIESMIEAGVEQGLDRKQAAALAMQTAL 219
Query: 289 GSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 113
G+A M + +G+ PA L+ VTSP G+T L+++ F I A+ A R + + ++
Sbjct: 220 GAAQMAITSGEAPAELRRKVTSPNGTTQAAIESLQQDDFAGIIKKAMQACYTRSEQISQE 279
Query: 112 LND 104
L D
Sbjct: 280 LAD 282
>UniRef50_A3H628 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Caldivirga maquilingensis IC-167|Rep:
Pyrroline-5-carboxylate reductase - Caldivirga
maquilingensis IC-167
Length = 187
Score = 122 bits (294), Expect = 9e-27
Identities = 70/178 (39%), Positives = 99/178 (55%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
ISV G++ + S ++ARVIR MPN L G A SRG +AT D + T LF A
Sbjct: 2 ISVVAGLSTKLLGSL--TKARVIRTMPNISILEGSGVTAVSRGPRATDADVEFTCSLFNA 59
Query: 457 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 278
VG C V E ++A+TALSGSGPAYV M++E+L + G+ GLP DLA L+ + S A
Sbjct: 60 VGKCYIVNEEYLNAVTALSGSGPAYVAMIVEALWEAGILIGLPSDLAWSLSID-VIESGA 118
Query: 277 MVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQLND 104
+ P + +V +P G T G E+ G + ++G + +A R V+K + D
Sbjct: 119 KLLNSKKPWEIISDVATPGGVTISGIKFAEERGLKGLLMGMIESAYRRSTDVQKTIED 176
>UniRef50_Q9HLT6 Cluster: Pyrroline-5-carboxylate reductase related
protein; n=2; Thermoplasma|Rep: Pyrroline-5-carboxylate
reductase related protein - Thermoplasma acidophilum
Length = 279
Score = 122 bits (293), Expect = 1e-26
Identities = 66/193 (34%), Positives = 110/193 (56%), Gaps = 2/193 (1%)
Frame = -3
Query: 682 LKEIKNLPSA-KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
+ E+K L + K+ +S+A + I + LP + ++R M N A V G F
Sbjct: 81 VSEMKKLSQILEGKIVVSMAAAVPIRVIRHILP-RSFIVRSMTNIAAEVNAGYTPFCTLE 139
Query: 505 KATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
+ + S++ G + V E MDA+TALSGSGPAY+ +IE++ GG++ GLPR
Sbjct: 140 EDEGK-ISFVSRVLGVFGETERVDEKYMDALTALSGSGPAYILTIIEAMMYGGLKVGLPR 198
Query: 325 DLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
+AL+ + QT +GSA ++ +GDHP+ +K+ V +P G T +G Y LE R++I+ A+
Sbjct: 199 SIALKASYQTVMGSAKLLAMSGDHPSAIKEKVITPGGVTIDGIYELENGKIRTSIMKAIE 258
Query: 148 AAVDRCKIVKKQL 110
++ + + + K L
Sbjct: 259 SSTLKARKISKDL 271
>UniRef50_Q8DJK6 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Synechococcus elongatus|Rep: Pyrroline-5-carboxylate
reductase - Synechococcus elongatus (Thermosynechococcus
elongatus)
Length = 273
Score = 121 bits (292), Expect = 2e-26
Identities = 72/183 (39%), Positives = 98/183 (53%), Gaps = 2/183 (1%)
Frame = -3
Query: 676 EIKNLPSAKNK-LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
E+ + P A+ + +S+ GI + P + R MPNTPA V G A + + A
Sbjct: 87 ELADTPVAQEMGVVLSIMAGIHSGRLRRLFPQRL-IFRAMPNTPAQVGAGVIALASDSAA 145
Query: 499 TAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 320
+ + Q L +G V E QMDA+TALSGSGPA+V +++E+L D GV GL R L
Sbjct: 146 SELEIQKIKNLLGVLGQVVAVSEGQMDAVTALSGSGPAFVALIVEALCDAGVAVGLSRSL 205
Query: 319 ALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
L T G+ ++K G HPA LKD V SPAG+T G LE G R ++ V AA
Sbjct: 206 TQELVYGTIAGTVQLLKERGLHPAQLKDAVASPAGTTIAGLEVLEAAGMRGTLMQTVKAA 265
Query: 142 VDR 134
+R
Sbjct: 266 YER 268
>UniRef50_Q12740 Cluster: Pyrroline-5-carboxylate reductase; n=7;
Ascomycota|Rep: Pyrroline-5-carboxylate reductase -
Zalerion arboricola
Length = 320
Score = 121 bits (292), Expect = 2e-26
Identities = 65/157 (41%), Positives = 94/157 (59%), Gaps = 1/157 (0%)
Frame = -3
Query: 577 RVIRVMPNTPALVKEGAAAFSRGTKA-TAEDAQLTSQLFKAVGTCDEVPEYQMDAITALS 401
+V+R MPNT + ++E + + +A + L + +FK +G ++P MDA TAL
Sbjct: 156 QVVRAMPNTASGIRESMTVIATSSPPLSATTSSLITWIFKRIGDVVQLPAATMDASTALC 215
Query: 400 GSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPA 221
GSGPA+ +++E+ DG V GLPR A R+AAQT G+A +V +G+HPA+LKD VT+P
Sbjct: 216 GSGPAFFALILEAAIDGAVAMGLPRAEAQRMAAQTMKGAAGLVLSGEHPALLKDKVTTPG 275
Query: 220 GSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 110
G T G LE+ G R G V+ AV +V QL
Sbjct: 276 GCTIGGLMVLEEGGVR----GTVARAVREATVVASQL 308
>UniRef50_Q0C2D9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Hyphomonas neptunium ATCC 15444|Rep:
Pyrroline-5-carboxylate reductase - Hyphomonas neptunium
(strain ATCC 15444)
Length = 268
Score = 121 bits (291), Expect = 2e-26
Identities = 72/171 (42%), Positives = 99/171 (57%), Gaps = 3/171 (1%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
IS+ G+ +A + L +E RVIR MPNTP + +G F+ A D +L
Sbjct: 90 ISIMAGVRLAQLSRRLGTE-RVIRSMPNTPGAIGQGVTVFTAPEGAKRTDLSAARELLAP 148
Query: 457 VGTCD-EVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA 281
+G V E M A+TALSGSGPAY+++L E +A+ GV GLPRDLAL LA +T G+A
Sbjct: 149 LGEVHGPVDEAMMSAVTALSGSGPAYIFLLAEVMAEAGVAQGLPRDLALSLARRTVEGAA 208
Query: 280 AMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAII-GAVSAAVDR 134
A++ ++GD P L+ VTSP G+T L G A+ A+SAA +R
Sbjct: 209 ALMGESGDSPEALRKAVTSPGGTTQAALDILMDTGGMPALFRNALSAAANR 259
>UniRef50_A1TY17 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Marinobacter|Rep: Pyrroline-5-carboxylate reductase -
Marinobacter aquaeolei (strain ATCC 700491 / DSM 11845 /
VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
11845))
Length = 277
Score = 120 bits (290), Expect = 3e-26
Identities = 64/182 (35%), Positives = 104/182 (57%), Gaps = 2/182 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L +S+A G+T T+++ L ++RVMPNTP+LV +GAA ++ + ++F
Sbjct: 94 LMVSIAAGLTAGTLDTWLGGGLPLVRVMPNTPSLVGKGAAGLFANSQVKDDQRNAVQKVF 153
Query: 463 KAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
+++G+ V E + ++TALSGSGPAY ++++E+L G+ + A LA QT G
Sbjct: 154 ESIGSALWVDDENLLHSVTALSGSGPAYFFLMLEALESAATEAGIESETARALAIQTMAG 213
Query: 286 SAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 110
+A M ++ D P LK NV SP G+T E+ G R + A SAA +R + + ++L
Sbjct: 214 AAEMAARSEDDPGQLKRNVMSPGGTTERAINTFEEGGLRDLVKKAYSAAFERSREMSREL 273
Query: 109 ND 104
D
Sbjct: 274 AD 275
>UniRef50_A5UQB8 Cluster: Pyrroline-5-carboxylate reductase; n=5;
Chloroflexi (class)|Rep: Pyrroline-5-carboxylate
reductase - Roseiflexus sp. RS-1
Length = 272
Score = 120 bits (289), Expect = 4e-26
Identities = 68/183 (37%), Positives = 103/183 (56%), Gaps = 2/183 (1%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+ +L IS+A G+ I T L A V+R MPNTPA + EG ++ + + E
Sbjct: 91 EGELVISIAAGVPIRTYVQGLAHGA-VVRAMPNTPAQIGEGMTVWTASSAVSEEQRGWAR 149
Query: 472 QLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
+ + G V E +D TA++G+GPAY++M++E++ D GV GLPR +A L QT
Sbjct: 150 AILGSFGRQMFVDDETYLDMATAINGTGPAYIFMVLEAMIDAGVHLGLPRYMAEELVLQT 209
Query: 295 TLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 119
LGS +++ HPA L++ VTSP G+TA Y LE+ G R+ + A+ AA R +
Sbjct: 210 MLGSVHYAMQSRRHPAELRNGVTSPGGTTAAALYELERGGLRTVLSDAIWAAYRRSAELG 269
Query: 118 KQL 110
K +
Sbjct: 270 KMM 272
>UniRef50_Q1AVY1 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
Pyrroline-5-carboxylate reductase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 262
Score = 119 bits (287), Expect = 7e-26
Identities = 74/186 (39%), Positives = 101/186 (54%), Gaps = 1/186 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+EI + + SVA G+ I T+ES LP V+RVMPN A V GAA +
Sbjct: 76 LEEISPAMGSGGRSVTSVAAGVEIRTIESYLPEGTPVLRVMPNVCASVGLGAAVITANEP 135
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
++ +F VG E+PE DA TAL GSGPAYV + ++L GVR GLPR+
Sbjct: 136 GRRVLPEVMD-IFGRVGEVMELPERLFDAATALHGSGPAYVALFADALIQAGVREGLPRE 194
Query: 322 LALRLAAQTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+A RL T G+A ++K D A ++D V +P G+TA +EK GF A+ V+A
Sbjct: 195 VARRLVVGTLAGTAVLLK--DRSAHQVRDEVMTPGGTTAAAFVAMEKAGFVGAVYDGVNA 252
Query: 145 AVDRCK 128
A R +
Sbjct: 253 ATRRAR 258
>UniRef50_Q1FII0 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Clostridium phytofermentans ISDg
Length = 265
Score = 119 bits (286), Expect = 9e-26
Identities = 64/168 (38%), Positives = 90/168 (53%), Gaps = 1/168 (0%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+ K+ ISVA G E+ L + +PNTP + EG T E+ +
Sbjct: 90 QKKIVISVAAGYPFDKYEAILVPGTHHLSTIPNTPVSIGEGIIICENHHSLTKEEYDTVA 149
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
LF + + V Q+ LSG GPA+V M +E+LADG V+ GLPRD + RLA+Q
Sbjct: 150 DLFSKIALLEFVDTKQLTVAGTLSGCGPAFVSMFLEALADGAVKHGLPRDTSYRLASQMV 209
Query: 292 LGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
G+ + ++TG HP +KD V SP G+T G LE+ G RSA+I A+
Sbjct: 210 AGTGKLQIETGAHPGAMKDAVCSPGGTTIVGVATLERKGLRSAVIEAI 257
>UniRef50_Q9KCR6 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacillus halodurans|Rep: Pyrroline-5-carboxylate
reductase - Bacillus halodurans
Length = 279
Score = 118 bits (285), Expect = 1e-25
Identities = 69/187 (36%), Positives = 104/187 (55%), Gaps = 1/187 (0%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
A++EI+ + K +LFISV G T + +E+ L E V+R MPNT A V A G
Sbjct: 82 AIEEIRGEITEK-QLFISVLAGTTTSYIETLLAHEVPVVRTMPNTSAKVGASATGLCGGR 140
Query: 505 KATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
A A +L + +F A+GT EV E ++DA+T L+GSGPAY Y ++E++ V+ GL
Sbjct: 141 YANASHVKLATLIFTAIGTVTEVTEDKLDAVTGLAGSGPAYFYYMVEAMERAAVQSGLTE 200
Query: 325 DLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
A +QT +G+ + +T L V SP G+T G LE+ + AI A++
Sbjct: 201 SEAKAFISQTLIGTGKRLEQTSKTAEELYKEVMSPGGTTEAGLRVLEQQQMQQAIEEAIT 260
Query: 148 AAVDRCK 128
AA++R +
Sbjct: 261 AAINRSR 267
>UniRef50_Q82X95 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=2; Nitrosomonas|Rep: Delta 1-pyrroline-5-carboxylate
reductase - Nitrosomonas europaea
Length = 270
Score = 118 bits (285), Expect = 1e-25
Identities = 68/177 (38%), Positives = 100/177 (56%), Gaps = 2/177 (1%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+NKL IS+A G+ + + L VIR MPNTPAL+ EG + + +
Sbjct: 85 QNKLVISIAAGVRASDLSQWLNRHEFVIRAMPNTPALIGEGITGLYALPLVDSRQKEQAT 144
Query: 472 QLFKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
+ +A+GT V E Q+DA+TALSGSGPAYV+ +E++ + G + GL D A +LA QT
Sbjct: 145 TILEAIGTVIWVNEEAQLDAVTALSGSGPAYVFYFLEAMQEAGTQLGLTADTAKQLAMQT 204
Query: 295 TLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
LG+ + ++ D A L+ VTS G+T + +E+ R A I A+ AA DR +
Sbjct: 205 FLGATHLAAQSNDTLATLRMKVTSQGGTTEQALLSMEQADIRGAFIRAMHAACDRSR 261
>UniRef50_Q1UAB2 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=2; Lactobacillus reuteri|Rep: Delta
1-pyrroline-5-carboxylate reductase - Lactobacillus
reuteri 100-23
Length = 257
Score = 118 bits (283), Expect = 2e-25
Identities = 63/168 (37%), Positives = 97/168 (57%), Gaps = 1/168 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
+FIS A GIT A + LP++ ++ ++PNTP V G + T +AE +
Sbjct: 87 IFISAAAGITHADLAKVLPNK-EIVNIIPNTPVEVNAGTIGLALPTGISAEAISKVMTVL 145
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
++G EVPE Q+D I + G GPA+V +++++++D V+ GL R A + A G+
Sbjct: 146 DSLGDVIEVPERQLDIIGVIGGCGPAFVDVMMDAMSDAAVKHGLDRQTAYEVIASMVKGT 205
Query: 283 AAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
+ PA+L+D VTSPAG+T +G LEKNGFR A++ AV+ A
Sbjct: 206 GTLAYDSKLAPALLRDQVTSPAGTTIKGVEALEKNGFRYALMDAVNKA 253
>UniRef50_A6DTF8 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Lentisphaera araneosa HTCC2155|Rep:
Pyrroline-5-carboxylate reductase - Lentisphaera
araneosa HTCC2155
Length = 266
Score = 118 bits (283), Expect = 2e-25
Identities = 69/178 (38%), Positives = 101/178 (56%), Gaps = 2/178 (1%)
Frame = -3
Query: 661 PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQ 482
P K++ F+S+ GIT+ +E L ++ +V R MPNTP V +GA A+ + D
Sbjct: 82 PMVKDQYFVSICAGITLDNLEQWLGTD-KVTRTMPNTPLCVSKGAVAYCSASGVGESDLA 140
Query: 481 LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAA 302
L +Q F+ G +V E ++ ITALSGSGPAYV+ +I++LA GL ++AL +
Sbjct: 141 LLTQYFECSGILAKVAEDDINTITALSGSGPAYVFEMIDALAQSAKANGLSDEVALAFSI 200
Query: 301 QTTLGSAAMV--KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
QT LGSA M+ K G P L++ VTSP G+T + ++N R + AA DR
Sbjct: 201 QTFLGSAQMLSDKLGT-PEELRNAVTSPNGTTYAALENFKQNNLREVLHQGFQAAKDR 257
>UniRef50_A3IBB9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacillus sp. B14905|Rep: Pyrroline-5-carboxylate
reductase - Bacillus sp. B14905
Length = 267
Score = 118 bits (283), Expect = 2e-25
Identities = 72/187 (38%), Positives = 103/187 (55%), Gaps = 1/187 (0%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
A++E+K +A++ + +S+ GI I T+ L S V RVMPNT A + A+ +
Sbjct: 78 AMRELKPKITAQSAI-LSILAGIGIGTITELLGSRP-VARVMPNTSATIGMSASGIAFNN 135
Query: 505 KATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
+ + L QL +AVG+ EV E Q+ A+TALSGSGPAY+Y L+E+ G GL +
Sbjct: 136 EVSTAQRILFLQLLEAVGSVIEVEEDQLHAVTALSGSGPAYIYYLMEAFERVGTEVGLSK 195
Query: 325 DLALRLAAQTTLGSAAMVKTG-DHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
D L QT G+A M+K D P +L+ VTSP G+T G LE+ F AI +
Sbjct: 196 DTVRLLMTQTLAGTAEMLKQSVDEPDVLRKKVTSPGGTTEAGIQALEQYQFNEAIEACIK 255
Query: 148 AAVDRCK 128
A R +
Sbjct: 256 EAEARSR 262
>UniRef50_Q9PA08 Cluster: Pyrroline-5-carboxylate reductase; n=14;
Gammaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Xylella fastidiosa
Length = 305
Score = 116 bits (280), Expect = 5e-25
Identities = 70/186 (37%), Positives = 100/186 (53%), Gaps = 3/186 (1%)
Frame = -3
Query: 664 LPSAKNK-LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAED 488
LP N L IS+A GIT ++ L ++R MPNTPAL+ G + TA
Sbjct: 113 LPVQPNTPLVISIAAGITTCKLKHWLGDTCAIVRAMPNTPALLGAGVTGLFATSHTTATQ 172
Query: 487 AQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 311
L +LF +VG T E MDA+TA+SGSGPAY ++L E++ + GL A
Sbjct: 173 RTLAEELFNSVGKTLWITEEALMDAVTAVSGSGPAYAFLLAEAMEAAAIMQGLSTANART 232
Query: 310 LAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
L QT LG+A M+ + G+ PA L+ VTSP G+T ++N F++ + A+ AA R
Sbjct: 233 LVQQTLLGAARMMTELGETPAALRHRVTSPHGTTEAAIATFQENDFQALVAKAIDAATRR 292
Query: 133 CKIVKK 116
+ + K
Sbjct: 293 ARALGK 298
>UniRef50_Q6N1N9 Cluster: Pyrroline-5-carboxylate reductase; n=23;
Alphaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Rhodopseudomonas palustris
Length = 280
Score = 116 bits (279), Expect = 6e-25
Identities = 73/179 (40%), Positives = 94/179 (52%), Gaps = 3/179 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L +S+ G IA + L V+R MPNTPA + G TA + L
Sbjct: 104 LVVSIMAGKPIAALSEQLGGH--VVRAMPNTPAAIGRGITVAVAAGNVTAAQRGIADALL 161
Query: 463 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
+A G + V E +DA+TA+SGSGPAYV++L E LA GV GLP LA+ LA T G
Sbjct: 162 RATGGVEWVDDEALIDAVTAVSGSGPAYVFLLAEELARAGVEAGLPEGLAMTLARATVAG 221
Query: 286 SAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKN-GFRSAIIGAVSAAVDRCKIVKK 116
S ++ D A L+ NVTSP G+TA L N GFR + AV+AA R K + K
Sbjct: 222 SGELLHRSDLDAATLRKNVTSPGGTTAAALEVLMANDGFRPLLTRAVAAATKRSKELAK 280
>UniRef50_Q1MPA3 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Lawsonia intracellularis PHE/MN1-00|Rep:
Pyrroline-5-carboxylate reductase - Lawsonia
intracellularis (strain PHE/MN1-00)
Length = 278
Score = 116 bits (279), Expect = 6e-25
Identities = 71/190 (37%), Positives = 101/190 (53%), Gaps = 3/190 (1%)
Frame = -3
Query: 688 PALKEIKNLPSAK-NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFS- 515
P LKE LP + + IS+A GIT + + S VIRVMPNTPALV G A
Sbjct: 85 PILKEC--LPFLRPGHIIISLAAGITQIMLTEAVESFCPVIRVMPNTPALVGSGIFALCL 142
Query: 514 RGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCG 335
K + E +Q LF +G +PE Q A TAL G GPAYV+ +++L + V G
Sbjct: 143 EDPKLSNEQSQSVIDLFSLIGLPIILPEKQFSAFTALIGCGPAYVFHFMDALVEAAVTLG 202
Query: 334 LPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 158
PR ++ + ++ GSA + + G+HPA+L++ V SP G T H+++ R II
Sbjct: 203 FPRQQSIYMVSELLNGSAKLATQPGNHPALLREQVCSPGGITIAAINHMDRTAIRGNIID 262
Query: 157 AVSAAVDRCK 128
A+ A + K
Sbjct: 263 AILTAYKKEK 272
>UniRef50_Q9CPE8 Cluster: Pyrroline-5-carboxylate reductase; n=93;
Proteobacteria|Rep: Pyrroline-5-carboxylate reductase -
Pasteurella multocida
Length = 275
Score = 116 bits (279), Expect = 6e-25
Identities = 68/180 (37%), Positives = 100/180 (55%), Gaps = 3/180 (1%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
KL IS+A G+++ ++S LP+ +++RVMPNTPALV EG + E Q T L
Sbjct: 94 KLVISIAAGVSVTKLQSRLPTAKQIVRVMPNTPALVAEGMSGLFAQNSLKPEYKQFTQDL 153
Query: 466 FKAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
AVG TC E M ITA SGS PAY ++ +E++ + + D A L Q+ L
Sbjct: 154 LNAVGKTCWVTQEADMHTITAGSGSSPAYFFLFMEAMQQALCQMNMDEDTARLLVQQSAL 213
Query: 289 GSAAMV-KTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 116
G+A MV + D P A L++NVTS G+TA L + + + A+ A V+R + ++K
Sbjct: 214 GAAKMVIENPDLPIATLRENVTSKGGTTAAALQVLNQQQLQHIVQQAMQACVERSQQMEK 273
>UniRef50_A6GTV0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Limnobacter sp. MED105|Rep: Pyrroline-5-carboxylate
reductase - Limnobacter sp. MED105
Length = 268
Score = 116 bits (278), Expect = 8e-25
Identities = 66/179 (36%), Positives = 101/179 (56%), Gaps = 3/179 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVES-NLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
L IS+A G+++A +++ + ARV+R MPNTPALV +G + + + ED + Q+
Sbjct: 87 LIISIAAGVSVAQIQNWSQQGNARVVRCMPNTPALVSQGISGLFFTSNCSVEDRNIAQQI 146
Query: 466 FKAVGTCDEVPEY-QMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
F + G + E +++A+TA+SGSGP YV+ L+E+LA+ G A L +QT L
Sbjct: 147 FSSCGEVLVLNEEDEINAVTAISGSGPGYVFFLMEALAEAAKNLGFNESQANLLVSQTFL 206
Query: 289 GSAAMVKTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 116
G+A + K D A L++ VTS G+T G L G + AI A AA R ++K
Sbjct: 207 GAATLAKQSDDSFATLREKVTSKGGTTFAGLEQLRALGVQDAIKSAAKAACTRAVELQK 265
>UniRef50_Q20848 Cluster: Putative pyrroline-5-carboxylate
reductase; n=2; Caenorhabditis|Rep: Putative
pyrroline-5-carboxylate reductase - Caenorhabditis
elegans
Length = 299
Score = 116 bits (278), Expect = 8e-25
Identities = 73/198 (36%), Positives = 107/198 (54%), Gaps = 15/198 (7%)
Frame = -3
Query: 658 SAKNKLFISVAMGITIATVESNLP---SEARVIRVMPNTPALVKEGAAA--FSRGTKATA 494
+++ + ISV G+ + + + LP ++R+MPN + + GA+ + + K
Sbjct: 100 NSRPEFIISVMAGVPLKVLNAKLPFVSGNTTIVRLMPNVASSIGAGASTMCYEKNEKIMN 159
Query: 493 EDA--QLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 320
+D+ +L + + VGT + +PE + A+ GS PA+ +M IESLADG V GL R
Sbjct: 160 QDSHIELAREFAECVGTVELIPERCFNPAMAIGGSSPAWTFMYIESLADGAVAQGLGRAE 219
Query: 319 ALRLAAQTTLGSAAMVKTGD--------HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAI 164
A RLAAQ LG+A MV + H LKD V SP G+T EG LEKNGFR A+
Sbjct: 220 AKRLAAQAVLGAAQMVLNSNSGFDIETQHFGSLKDMVCSPGGTTIEGVRALEKNGFRYAV 279
Query: 163 IGAVSAAVDRCKIVKKQL 110
+ AV AA + + K L
Sbjct: 280 MEAVVAASTKADEMAKSL 297
>UniRef50_Q89DI5 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=10; Alphaproteobacteria|Rep: Delta
1-pyrroline-5-carboxylate reductase - Bradyrhizobium
japonicum
Length = 292
Score = 114 bits (275), Expect = 2e-24
Identities = 70/190 (36%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = -3
Query: 676 EIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKAT 497
++K S K + +S+ G TIA+++ V+R MPNTPA + G +
Sbjct: 106 KLKPFVSEKTSV-VSIMAGTTIASLQE--VCGGAVVRAMPNTPAAIGRGITVAVAAKNVS 162
Query: 496 AEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 320
+ L +A G+ + V E MDA+TA+SGSGPAYV++L E LA GV GLP L
Sbjct: 163 TAQRAVADALLRATGSVEWVEDESLMDAVTAVSGSGPAYVFLLAEELARAGVEAGLPEAL 222
Query: 319 ALRLAAQTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGT-YHLEKNGFRSAIIGAVSA 146
A +LA +T GS ++ + P+ L+ NVTSP G+TA + + G R +I A++A
Sbjct: 223 ATKLARETVAGSGELLHQSELPSGTLRQNVTSPGGTTAAALGVLMGEPGLRDLMIRAIAA 282
Query: 145 AVDRCKIVKK 116
A R K + K
Sbjct: 283 ATQRSKELAK 292
>UniRef50_Q88Z19 Cluster: Pyrroline-5-carboxylate reductase; n=5;
Lactobacillaceae|Rep: Pyrroline-5-carboxylate reductase
- Lactobacillus plantarum
Length = 263
Score = 114 bits (275), Expect = 2e-24
Identities = 64/183 (34%), Positives = 98/183 (53%), Gaps = 1/183 (0%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
ALKE++ + K I++ G+++A + P + V+R+MPN + G A
Sbjct: 77 ALKEVQ--AALTGKWVITMVSGLSLADYATVAP-DLPVLRIMPNVNVAIGAGMTALVGND 133
Query: 505 KATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
T E QLF A+G + E +AL+GS PAY+Y I+++A GV+ GL +
Sbjct: 134 ALTPEQYAAGQQLFDAIGATSAIAEKDFPTFSALAGSSPAYIYFFIDAMARAGVKHGLSK 193
Query: 325 DLALRLAAQTTLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
D A ++AAQ TLGSA V D P L D V+SP G+T G +E+ GF +A++ +
Sbjct: 194 DAATKIAAQATLGSAQNVLASDKIPFDLIDQVSSPGGTTVAGLLAMEEAGFMTAVVKGID 253
Query: 148 AAV 140
A +
Sbjct: 254 ATI 256
>UniRef50_A6Q4P9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Nitratiruptor sp. SB155-2|Rep: Pyrroline-5-carboxylate
reductase - Nitratiruptor sp. (strain SB155-2)
Length = 244
Score = 114 bits (275), Expect = 2e-24
Identities = 68/187 (36%), Positives = 112/187 (59%), Gaps = 1/187 (0%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
AL+++ N S K +L IS+ G I+T+ +P++ + +R MPN A +K+ + T
Sbjct: 67 ALEDVANQVSGKAELLISILAGTPISTLHK-IPAQ-KYVRAMPNIAA-IKQASI-----T 118
Query: 505 KATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
T + + +L + +G V E ++D TA++GSGPA++ ++ E++ADGGV CGL
Sbjct: 119 AMTGDKDERAIELIEKIGKVVWVESEKELDIATAIAGSGPAFLALVAEAMADGGVLCGLK 178
Query: 328 RDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
RD+A L + AA+ + +HPA++KD V SPAG+TA G LE+NG R+ I ++
Sbjct: 179 RDIAYGLVSGLFQSYAAI--SEEHPALIKDKVMSPAGTTAAGYKALEENGVRNGFIQSIQ 236
Query: 148 AAVDRCK 128
A ++ K
Sbjct: 237 KAFEKTK 243
>UniRef50_P32263 Cluster: Pyrroline-5-carboxylate reductase; n=7;
Saccharomycetales|Rep: Pyrroline-5-carboxylate reductase
- Saccharomyces cerevisiae (Baker's yeast)
Length = 286
Score = 114 bits (275), Expect = 2e-24
Identities = 67/169 (39%), Positives = 93/169 (55%), Gaps = 1/169 (0%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
KL IS+A G TI + + V RVM NTPA G A S + E L ++L
Sbjct: 109 KLLISLAAGWTIDQLSQYTST---VCRVMTNTPAKYGYGCAVVSYSADVSKEQKPLVNEL 165
Query: 466 FKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
VG E+PE MDA TAL GSGPA+V +++ESL + G++ G+P + A + G
Sbjct: 166 ISQVGKYVELPEKNMDAATALVGSGPAFVLLMLESLMESGLKLGIPLQESKECAMKVLEG 225
Query: 286 SAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
+ MV K+G HP++LK V +P G+T G +E+ G +S II V A
Sbjct: 226 TVKMVEKSGAHPSVLKHQVCTPGGTTIAGLCVMEEKGVKSGIINGVEEA 274
>UniRef50_O66553 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Aquifex aeolicus|Rep: Pyrroline-5-carboxylate reductase
- Aquifex aeolicus
Length = 265
Score = 114 bits (274), Expect = 2e-24
Identities = 59/173 (34%), Positives = 95/173 (54%), Gaps = 1/173 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
+ +S+ G++I +E L + +++RVMPN V G A + + E+ +L
Sbjct: 91 IILSIMAGVSIEKMEKILGKDKKIVRVMPNVNVAVGSGVMAITDNGNLSEEERSKVEELL 150
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
+ GT + E DA TAL+GSGPA+V+ I++LA GV G + ALR+A T +GS
Sbjct: 151 LSCGTLYRIEERLFDAFTALAGSGPAFVFSFIDALALAGVHQGFSYEQALRIALDTVMGS 210
Query: 283 AAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
A ++K +P L VTSP G+T EG +LE+ GF+ ++ ++ + K
Sbjct: 211 AKLLKEFQVNPNELIAKVTSPGGTTIEGIKYLEEKGFKGTVMECINRTSQKAK 263
>UniRef50_A3UFN9 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Hyphomonadaceae|Rep: Pyrroline-5-carboxylate reductase -
Oceanicaulis alexandrii HTCC2633
Length = 282
Score = 113 bits (273), Expect = 3e-24
Identities = 70/185 (37%), Positives = 102/185 (55%), Gaps = 3/185 (1%)
Frame = -3
Query: 679 KEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
K ++LP + L IS+A G+ + T+ + LP ++R MPNTPA + EG + A
Sbjct: 89 KVSEDLP--EGALVISIAAGVPLRTLSAALPGRP-IVRAMPNTPAAIGEGVSVCVANEAA 145
Query: 499 TAEDA-QLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
+ + +L K G + + E MDA+TA+SGSGPAYV++ E+LA GL R
Sbjct: 146 DTKTLIRQAERLLKPAGLVEWISDERMMDAVTAVSGSGPAYVFLFTEALAAAAEAEGLSR 205
Query: 325 DLALRLAAQTTLGSAAMVKTG-DHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
+LA+ LA QT +G+ AM+K G P L+ NVTSP G+T G L G ++
Sbjct: 206 ELAMTLAKQTVIGAGAMMKAGLGEPDELRRNVTSPNGTTQAGLDALMSGGGLPGLVRNAV 265
Query: 148 AAVDR 134
AA +R
Sbjct: 266 AAAER 270
>UniRef50_Q4TIV0 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Euteleostomi|Rep: Pyrroline-5-carboxylate reductase -
Tetraodon nigroviridis (Green puffer)
Length = 377
Score = 113 bits (272), Expect = 4e-24
Identities = 54/99 (54%), Positives = 69/99 (69%)
Frame = -3
Query: 586 SEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITA 407
S +V+R M NTP +VKEGA ++ GT A ED +L QL +VG C EV E +DA+T
Sbjct: 165 SAPKVMRCMTNTPVVVKEGATVYATGTHAEVEDGKLLEQLMASVGFCTEVEEDLIDAVTG 224
Query: 406 LSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
LSGSGPAY + +++LADGGV+ GLPR LA+RL AQ L
Sbjct: 225 LSGSGPAYAFTALDALADGGVKMGLPRRLAVRLGAQALL 263
>UniRef50_Q0VL32 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Alcanivorax borkumensis SK2|Rep: Pyrroline-5-carboxylate
reductase - Alcanivorax borkumensis (strain SK2 / ATCC
700651 / DSM 11573)
Length = 269
Score = 113 bits (272), Expect = 4e-24
Identities = 66/185 (35%), Positives = 105/185 (56%), Gaps = 4/185 (2%)
Frame = -3
Query: 676 EIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKAT 497
++++L + + L IS+A G+T+ + L S ++R MPNTP+LV+ GA +
Sbjct: 82 DLRDLIAERQPLVISIAAGVTVGNLRRWLGSTP-IVRCMPNTPSLVQAGATGLYAADDVS 140
Query: 496 AEDAQLTSQLFKAVGTC---DEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
E + ++ +VG DE E ++DA+TA+SGSGPAY ++L+ESL + GL
Sbjct: 141 DEQKAMAKEILGSVGIAFWFDE--EKELDAVTAVSGSGPAYFFLLMESLIEAAKAQGLDA 198
Query: 325 DLALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
A ++ QT G+A + T + P +L+ VTSP G+TA E+ GFR + AV+
Sbjct: 199 GTARQMVLQTAWGAAQLAITSEVGPDVLRQQVTSPGGTTAAALGVFEEAGFREQVQAAVA 258
Query: 148 AAVDR 134
AA +R
Sbjct: 259 AARER 263
>UniRef50_A3ERR0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Leptospirillum sp. Group II UBA|Rep:
Pyrroline-5-carboxylate reductase - Leptospirillum sp.
Group II UBA
Length = 288
Score = 113 bits (272), Expect = 4e-24
Identities = 65/171 (38%), Positives = 100/171 (58%), Gaps = 1/171 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L +SV G ++T++ +LP R IR M N EG + G +A ED S++F
Sbjct: 102 LGVSVMAGTPLSTLQESLP-RWRWIRTMSNLALTRGEGMTLLTPGARAQDEDLSAVSRIF 160
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
+G +PE D TAL+GSGP + +++E+L+D GVR GL R+ A+ L+AQ G+
Sbjct: 161 LELGRVMMLPEKDFDVATALAGSGPGLMALVLEALSDAGVRHGLKREDAVFLSAQMLKGT 220
Query: 283 AAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
A+++ + G P+ L+ V SP+G+T EG LE+ G R++ I AV+ V R
Sbjct: 221 ASLILEEGMDPSELRKRVASPSGTTIEGLVALEEGGVRASFIQAVARMVGR 271
>UniRef50_Q12641 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Neurospora crassa|Rep: Pyrroline-5-carboxylate reductase
- Neurospora crassa
Length = 311
Score = 113 bits (272), Expect = 4e-24
Identities = 63/177 (35%), Positives = 100/177 (56%), Gaps = 9/177 (5%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEAR--------VIRVMPNTPALVKEGAAAFSRGTKATAE 491
K+ IS+ G+T+ +E L + V+R MPNT + ++E + +
Sbjct: 115 KIIISICAGVTVPDLERVLREDVGLSADNLPIVVRAMPNTASKIRESMTVINTVDPPLPD 174
Query: 490 DA-QLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLAL 314
+L + +F+ +G +P + MDA T+L SG A+ +++E+ ADGGV GLPR A
Sbjct: 175 TVTELLTWIFERIGEVVYLPPHLMDACTSLCASGTAFFALMMEAAADGGVAMGLPRAEAN 234
Query: 313 RLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
R+AAQT G+A +V G+HPA+L++ V++P G T G LE+ G R+A+ AV A
Sbjct: 235 RMAAQTMRGAAGLVLEGEHPAILREKVSTPGGCTIGGLLVLEEGGVRAAVARAVREA 291
>UniRef50_Q3Y1B7 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=2; Lactobacillales|Rep: Delta
1-pyrroline-5-carboxylate reductase - Enterococcus
faecium DO
Length = 283
Score = 112 bits (270), Expect = 8e-24
Identities = 61/172 (35%), Positives = 96/172 (55%), Gaps = 2/172 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPS-EARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
LFIS+A G ++ +E+ L +A ++RVMPN V G +A + AT E Q + +
Sbjct: 104 LFISIASGKSLTDLETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMI 163
Query: 466 FKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
F+A+G+ + E L+GS PA+VYMLI+++ GV GL + A +AA+ +G
Sbjct: 164 FEAIGSVYPLAESDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMG 223
Query: 286 SAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
S + D +P L D V+SP G+T G LE+ GF AII ++ +++
Sbjct: 224 SCQKFLSSDKNPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEK 275
>UniRef50_A0NYJ6 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Stappia aggregata IAM 12614|Rep: Pyrroline-5-carboxylate
reductase - Stappia aggregata IAM 12614
Length = 272
Score = 112 bits (270), Expect = 8e-24
Identities = 65/179 (36%), Positives = 103/179 (57%), Gaps = 3/179 (1%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
A + L +SVA G ++ E + R MPNTPA+VK G A +A+
Sbjct: 91 ASDTLVLSVAAGTPVSKFEEFF-GHVPICRCMPNTPAMVKRGITAVYPTPAVSAQAKDDV 149
Query: 475 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
++L +VG + E Q+D +T +SGSGPAYV+ L E+L++ G + GLP ++A LA
Sbjct: 150 TRLLSSVGKVVWLDSEDQIDLVTGVSGSGPAYVFFLAEALSEAGRQAGLPEEIAQELAIA 209
Query: 298 TTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEG-TYHLEKNGFRSAIIGAVSAAVDRCK 128
T G+ ++ ++G+HP++L+ NVTSP G+TA + +G + + AV+AAV R +
Sbjct: 210 TVCGAGELMHQSGEHPSVLRKNVTSPNGTTAAALDVLMHADGLQPVMTEAVAAAVKRAR 268
>UniRef50_Q0U2X1 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 307
Score = 112 bits (270), Expect = 8e-24
Identities = 63/169 (37%), Positives = 93/169 (55%), Gaps = 9/169 (5%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVE--------SNLPSEARVIRVMPNTPALVKEGAAAFSRGTKAT 497
K K+ +S+ G+T +E S + RV+RVMPNT + V E + T
Sbjct: 120 KGKVLVSILAGVTQQQIEDFLYPEGASKVDGACRVVRVMPNTASFVGESMSVIQTSTPPL 179
Query: 496 AEDAQ-LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 320
+E L + +F ++G +P QMD TAL GSGPA+ +++E+ ADG V GLPR
Sbjct: 180 SESQHNLVNFVFSSIGRVVSLPPAQMDISTALCGSGPAFFALILEAAADGAVAMGLPRAE 239
Query: 319 ALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFR 173
A +AAQT G+ +V G+HPA+LKD V++P G H+ + G+R
Sbjct: 240 AQLMAAQTMRGTTGLVLNGEHPAVLKDKVSTPRG-VHHRRAHVARGGWR 287
>UniRef50_A6SCY1 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 301
Score = 112 bits (270), Expect = 8e-24
Identities = 60/174 (34%), Positives = 94/174 (54%), Gaps = 7/174 (4%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPS-------EARVIRVMPNTPALVKEGAAAFSRGTKATA 494
++K+ +S+ G+TI +ES L S A + R MPNT + V+E +A
Sbjct: 112 QDKVLVSLLAGVTIPDIESVLQSVGGKSYYPATIARAMPNTASFVRESITVIETPEATSA 171
Query: 493 EDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLAL 314
+ LF+++G + D TAL S PA+ +++++L DG V GL R A
Sbjct: 172 SHLLAINWLFESIGKIKHISATNFDTCTALGASTPAFFAIILDALIDGAVTLGLTRKDAT 231
Query: 313 RLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
+AAQ+ G AA+V G+HPA +K+N+T+P GST G LE+ R+ + GA+
Sbjct: 232 LMAAQSMKGCAALVLAGEHPASVKENITTPGGSTIMGVLALEQGNVRAVVAGAL 285
>UniRef50_Q5WH55 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacillus clausii KSM-K16|Rep: Pyrroline-5-carboxylate
reductase - Bacillus clausii (strain KSM-K16)
Length = 283
Score = 111 bits (267), Expect = 2e-23
Identities = 67/179 (37%), Positives = 93/179 (51%), Gaps = 1/179 (0%)
Frame = -3
Query: 667 NLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAED 488
+L + +L ISVA GI + T+ES LP++ VIR MPNT A V A S GT AT
Sbjct: 88 SLLDPQKQLVISVAAGIKLETLESWLPADTAVIRAMPNTSARVLASATTLSIGTYATEWQ 147
Query: 487 AQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRL 308
LF ++GT V E QMDA T ++GSGPAY+Y + E++ + + GL A L
Sbjct: 148 LAFAKTLFSSIGTVTVVDEQQMDAATGIAGSGPAYIYYVAEAMLNAAIAEGLSPAEARAL 207
Query: 307 AAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
QT G+A + + P L + SP G+T HL+ + + A+ AV R
Sbjct: 208 INQTIGGAAKQLSNSSKSPKDLYKEIMSPNGTTEAAIAHLDHSSAQELFQQAIHQAVKR 266
>UniRef50_Q0EXW9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Mariprofundus ferrooxydans PV-1|Rep:
Pyrroline-5-carboxylate reductase - Mariprofundus
ferrooxydans PV-1
Length = 268
Score = 111 bits (267), Expect = 2e-23
Identities = 68/173 (39%), Positives = 103/173 (59%), Gaps = 3/173 (1%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSE-ARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFK 461
+S+A G++I+++ L + A ++RVMPNTPALV EG + + A E + L +
Sbjct: 94 VSIAAGVSISSLAEWLSGKSANLVRVMPNTPALVGEGMSVLY--SDAGDEHHNRATYLMQ 151
Query: 460 AVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
A G + V E QM A+TA+SGSGPAY ++L E + GV GL +LA +LAAQT LG+
Sbjct: 152 ACGAVEWVDSEQQMHAVTAVSGSGPAYFFLLAEVMRASGVALGLSEELAGKLAAQTALGA 211
Query: 283 AAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
M+ ++G P +L+ VTSP G+T + + G + + A++AA R K
Sbjct: 212 GRMLAESGRTPEILRQQVTSPGGTTQAALDVMFEEGLPATVRKALAAASKRSK 264
>UniRef50_Q9YFV4 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Thermoprotei|Rep: Pyrroline-5-carboxylate reductase -
Aeropyrum pernix
Length = 279
Score = 111 bits (267), Expect = 2e-23
Identities = 70/195 (35%), Positives = 110/195 (56%), Gaps = 2/195 (1%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+EI+++ + K+ +SV G+ ++T+ L + V R MPN AL+ A + T
Sbjct: 82 LEEIRDV--MEGKIVVSVVAGVRLSTLSRALEG-SHVYRAMPNINALIGRSTTAVAEYTG 138
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
+ A + +G+ +PE MD TAL GS PAYV ++I+SL GGV GLPR+
Sbjct: 139 D--KRASFVESILSCMGSVYWIPEEWMDVWTALVGSMPAYVAVMIDSLTLGGVSAGLPRE 196
Query: 322 LALRLAAQTTLGSAA--MVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
+A + A TLG+ A + K HP++L+D VT+PAG+T EG +E G +A+I V
Sbjct: 197 VAFK-AVIDTLGATAEHLGKRDIHPSVLRDEVTTPAGTTIEGLKVIEGEGVDAALIRTVE 255
Query: 148 AAVDRCKIVKKQLND 104
AA R + + +++
Sbjct: 256 AAARRAAAIGEAIDN 270
>UniRef50_UPI000038E2C3 Cluster: hypothetical protein Faci_03001369;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03001369 - Ferroplasma acidarmanus fer1
Length = 261
Score = 111 bits (266), Expect = 2e-23
Identities = 64/194 (32%), Positives = 108/194 (55%), Gaps = 1/194 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
++EI++ +AK KL IS GIT++ ++ L ++ V R MP+ P LV++ A+S
Sbjct: 72 MEEIRS--AAKGKLVISFMAGITLSHMQEML-KDSMVARGMPSIPMLVQKSVTAYSY-KN 127
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
E + ++ K G+ + E MDA+T LSGSGPA+V ++ +S+ + G+ G+P+
Sbjct: 128 LDKEHKDVLEKVLKGFGSAVHIDESYMDAVTGLSGSGPAFVAIMADSMINAGILAGIPKI 187
Query: 322 LALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
A L T + + ++++ G + L+D V +P G+T G Y +EK R+AI AV
Sbjct: 188 QARELVIDTFINTMSLMREKGFSASDLRDEVMTPGGTTVAGIYEMEKANARTAIANAVLG 247
Query: 145 AVDRCKIVKKQLND 104
+ R K + K D
Sbjct: 248 SYRRAKEISKNSRD 261
>UniRef50_Q2UTF9 Cluster: Pyrroline-5-carboxylate reductase; n=5;
Pezizomycotina|Rep: Pyrroline-5-carboxylate reductase -
Aspergillus oryzae
Length = 299
Score = 111 bits (266), Expect = 2e-23
Identities = 69/195 (35%), Positives = 103/195 (52%), Gaps = 13/195 (6%)
Frame = -3
Query: 649 NKLFISVAMGITIATVE----------SNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
NKL ISVA G T +E SN A V+R +PN A V +G A
Sbjct: 102 NKLLISVAAGWTRQKLETTLYGSPTTTSNAEGRAWVVRTLPNIAASVSQGLTAIEISEPE 161
Query: 499 TAEDAQ-LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
E Q +T +F +G +P MDA TA++GS PA+ ++++++ D V G+PRD
Sbjct: 162 VPEHYQKITDAVFDNLGKTVHIPPTLMDATTAVAGSTPAFFAVIVDAMIDAAVAVGVPRD 221
Query: 322 LALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
LA + Q G+AA++++G HPA+L+D TSP G T G +E+ G R + A+ A
Sbjct: 222 LARTMTVQAMTGTAALLQSGMHPAVLRDQGTSPEGCTIGGLMVMEEAGVRGHVGRALREA 281
Query: 142 VDRCKIV--KKQLND 104
V +++ + LND
Sbjct: 282 VTIARLMDGTRHLND 296
>UniRef50_Q9WZ47 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Thermotoga|Rep: Pyrroline-5-carboxylate reductase -
Thermotoga maritima
Length = 255
Score = 109 bits (261), Expect = 9e-23
Identities = 56/171 (32%), Positives = 97/171 (56%), Gaps = 1/171 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
+ +S+ G+ I + +V R+MPN V EG A + + E+ +L L
Sbjct: 80 ILLSIVAGLKIEEIRKY--GIHKVARIMPNVAVRVGEGVLATAFSADMSLEERELVKSLL 137
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
+ +G E+ E A+TAL+GSGPA++++++E+ D ++ G+P D A L + GS
Sbjct: 138 EKLGFVVEIEEKLFSAVTALTGSGPAFIFVVVEAFLDAALKMGIPLDTAKELVYRLFKGS 197
Query: 283 AAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
A ++ +TG+HPA+ K V+SPAG+T EG +E+ RS +I ++ ++ R
Sbjct: 198 AELLTETGEHPALWKHRVSSPAGTTIEGLITMERFAVRSGVIESLISSYRR 248
>UniRef50_Q3MCP7 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=5; Nostocaceae|Rep: Delta 1-pyrroline-5-carboxylate
reductase - Anabaena variabilis (strain ATCC 29413 / PCC
7937)
Length = 314
Score = 109 bits (261), Expect = 9e-23
Identities = 63/172 (36%), Positives = 94/172 (54%), Gaps = 2/172 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L IS+ G +++++ L + V+R MPN V G +S + T T +
Sbjct: 131 LVISIVGGASVSSLCQGL-NHGAVVRTMPNIAVQVGHGTTVWSASSNVTEIQRSHTQIIL 189
Query: 463 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
+A+G E+ +D TALS +G +V++ IE++ D GV+ GL R A L T G
Sbjct: 190 QALGKEFVTQNEHYLDMATALSSAGTGFVFLYIEAMIDAGVQMGLTRIQAQELTLHTIAG 249
Query: 286 SAA-MVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
S M++T +HPA+L++ VTSP G TA G Y LEK G R++I A S A+ R
Sbjct: 250 SVELMLQTNEHPAVLRNKVTSPGGVTAAGIYELEKGGMRTSISNAFSTALSR 301
>UniRef50_Q18YN1 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Desulfitobacterium hafniense|Rep:
Pyrroline-5-carboxylate reductase - Desulfitobacterium
hafniense (strain DCB-2)
Length = 267
Score = 109 bits (261), Expect = 9e-23
Identities = 65/192 (33%), Positives = 102/192 (53%), Gaps = 1/192 (0%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
AL +I+ S+ N+L ISVA GI +A +E +LP +IR MPNT + V +G
Sbjct: 75 ALAQIREGISS-NQLLISVAAGIPLALLEKHLP-HCPIIRAMPNTSSAVLHSMTGLVKGQ 132
Query: 505 KATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
+ +F AVG + E Q++ + A+SGSGPAY Y+ E+L GV G +
Sbjct: 133 GVNEAKQRDVEDIFGAVGKYIWITEEQINPLIAMSGSGPAYFYLFTEALVKAGVDMGFSQ 192
Query: 325 DLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
++A LA +T +G+A M+ ++G P L+ VTSP G+T E + G + A
Sbjct: 193 EVAENLAKETLMGAAKMLAQSGKSPGELRVAVTSPKGTTQEALEVFREQGLEELVAQAAK 252
Query: 148 AAVDRCKIVKKQ 113
A R + ++++
Sbjct: 253 ACKHRAQAMERE 264
>UniRef50_A1AVF5 Cluster: Pyrroline-5-carboxylate reductase; n=2;
sulfur-oxidizing symbionts|Rep: Pyrroline-5-carboxylate
reductase - Ruthia magnifica subsp. Calyptogena
magnifica
Length = 286
Score = 108 bits (260), Expect = 1e-22
Identities = 63/194 (32%), Positives = 100/194 (51%), Gaps = 2/194 (1%)
Frame = -3
Query: 679 KEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
K++KN A N L IS+A G+ +E L ++R MPN PAL+ +G +
Sbjct: 92 KDLKN-KLAINTLIISIAAGVRSRDIERWLGDNQAIVRTMPNMPALLNQGITGLFANKQV 150
Query: 499 TAEDAQLTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
+ + L + +VG C V E +D ITA+SGSGPAY ++++ES+ G GL
Sbjct: 151 SDKQKSLAENILNSVGECLWVNDEGLLDVITAVSGSGPAYFFLMLESMTKVGAALGLDEA 210
Query: 322 LALRLAAQTTLGSAAMVKTG-DHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+A +L+ QT LG++ + + D P L++ VTS G+T + F I A+ A
Sbjct: 211 VAQKLSIQTALGASIVASSSEDSPQQLRNKVTSKNGTTQAAIESFQDQDFEVIIAHAMRA 270
Query: 145 AVDRCKIVKKQLND 104
A +R + +L +
Sbjct: 271 AFNRANEIGMELGN 284
>UniRef50_A3HTL9 Cluster: Putative pyrroline-5-carboxylate
reductase; n=1; Algoriphagus sp. PR1|Rep: Putative
pyrroline-5-carboxylate reductase - Algoriphagus sp. PR1
Length = 267
Score = 108 bits (259), Expect = 2e-22
Identities = 65/192 (33%), Positives = 100/192 (52%), Gaps = 1/192 (0%)
Frame = -3
Query: 688 PALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRG 509
P LKEIK + K ++ IS+A GI++A + L S+ R MPN A ++E +
Sbjct: 79 PLLKEIKPVLDPKKQVIISLATGISLAEMYEVLDSKTVTFRAMPNIAADIQESITCVCQ- 137
Query: 508 TKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
A+ + ++ QLF ++G ++ E M+A T L G AYV + ++ GG++ G
Sbjct: 138 QGASLKQIEIIKQLFDSIGITIDIDEKLMEAATVLGACGIAYVLRFMRAMIQGGIQIGFD 197
Query: 328 RDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
A R+ QT G+A M++ HP D VT+P G T G +E GF SA++ V
Sbjct: 198 SKTASRIVNQTVKGAAELMIQQNTHPEEAIDKVTTPKGCTIVGLNEMEHQGFSSAMVRGV 257
Query: 151 SAAVDRCKIVKK 116
A+ + KI KK
Sbjct: 258 IASFE--KIEKK 267
>UniRef50_Q974L3 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Sulfolobus tokodaii|Rep: Pyrroline-5-carboxylate
reductase - Sulfolobus tokodaii
Length = 259
Score = 108 bits (259), Expect = 2e-22
Identities = 65/184 (35%), Positives = 103/184 (55%), Gaps = 2/184 (1%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDA-QLT 476
+ K +SV GI I+T+ + L + A+V R MPN A++ + T A AE+ +
Sbjct: 82 EGKKVVSVMAGIRISTL-TRL-TNAKVYRAMPNINAVI-------GKATTALAEERDEEV 132
Query: 475 SQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
++F+ +G +PE DA TA+ GSGPA+V +I++ A G V CG+ R+LA +
Sbjct: 133 ERIFRTIGNVYWIPEELFDAWTAIIGSGPAFVAEIIDAFALGAVACGMSRELAYQAILDM 192
Query: 295 TLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 119
G+ + K HP +L+D VT+PAG+T G +E G +SAII + AA R +
Sbjct: 193 VEGTVYTLRKDKTHPVLLRDQVTTPAGTTIRGLMVMESEGIKSAIIKTIEAAYQRSMAIG 252
Query: 118 KQLN 107
K+++
Sbjct: 253 KEID 256
>UniRef50_P27771 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Treponema pallidum|Rep: Pyrroline-5-carboxylate
reductase - Treponema pallidum
Length = 263
Score = 108 bits (259), Expect = 2e-22
Identities = 71/184 (38%), Positives = 101/184 (54%), Gaps = 6/184 (3%)
Frame = -3
Query: 673 IKNLPSAKNKLFISVAMGITIATVESNLPSEA----RVIRVMPNTPALVKEGAA-AFSRG 509
+++ S + K+ IS+A G++ A E+ ++ R + ++PN P V G A +R
Sbjct: 78 LRDRQSFQGKVLISLAAGMSCAAYEALFAADPHQGIRHLSLLPNLPCQVARGVIIAEARH 137
Query: 508 TKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
T E A L + L + V + V ++G PA+ IE+LAD GVR GL
Sbjct: 138 TLHHDEHAALLAVL-RTVAQVEVVDTAYFAIAGVIAGCAPAFAAQFIEALADAGVRYGLA 196
Query: 328 RDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
RD A RLAA G+AA+++ +G HPA LKD V SPAGST G LE+ G R A+I AV
Sbjct: 197 RDQAYRLAAHMLEGTAALIQHSGVHPAQLKDRVCSPAGSTIRGVLALEEQGLRRAVIHAV 256
Query: 151 SAAV 140
AA+
Sbjct: 257 RAAL 260
>UniRef50_Q6MC43 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Candidatus Protochlamydia amoebophila UWE25|Rep:
Pyrroline-5-carboxylate reductase - Protochlamydia
amoebophila (strain UWE25)
Length = 264
Score = 107 bits (258), Expect = 2e-22
Identities = 63/183 (34%), Positives = 99/183 (54%), Gaps = 1/183 (0%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
++ +S+ GI T++ S++ V+R+MPN + +G + T +
Sbjct: 83 HQTIVSILAGINYKTLKHRF-SQSIVVRMMPNLALIHGKGVIGLVENDQLTDKLKMQLKA 141
Query: 469 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
LF +G+ +PE ++DA+TAL+GSGPA+++ L+ES+ + G+ G A L Q
Sbjct: 142 LFDPLGSVYWLPESKIDALTALTGSGPAFIFALVESMIEAGIYMGFQMTDAKSLIFQMLK 201
Query: 289 GSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 113
GS A+++T D HPA LK +TSPAG T EG E G RS II A+ ++ K V
Sbjct: 202 GSLALLETTDKHPADLKWQITSPAGMTIEGLKTFEDYGVRSGIIHTFLASFNKIKQVSDS 261
Query: 112 LND 104
L +
Sbjct: 262 LKN 264
>UniRef50_Q5XE84 Cluster: Pyrroline-5-carboxylate reductase; n=14;
Streptococcus|Rep: Pyrroline-5-carboxylate reductase -
Streptococcus pyogenes serotype M6
Length = 256
Score = 107 bits (258), Expect = 2e-22
Identities = 59/188 (31%), Positives = 97/188 (51%), Gaps = 1/188 (0%)
Frame = -3
Query: 688 PALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRG 509
P L E P + IS+A GI++ + + + + ++R+MPN A + + + A +
Sbjct: 67 PQLFETVLKPLHFKQPIISMAAGISLQRLATFVGQDLPMLRIMPNMNAQILQSSTALTGN 126
Query: 508 TKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
+ E L + G+ ++ E D TAL+GS PAY+Y+ IE+LA GV+ G+P
Sbjct: 127 ALVSQELQARVRDLTDSFGSTFDISEKDFDTFTALAGSSPAYIYLFIEALAKAGVKNGMP 186
Query: 328 RDLALRLAAQTTLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
+ AL + QT L SA+ +KT P D + SP G+T G LE+ G + + A+
Sbjct: 187 KAKALEIVTQTVLASASNLKTSSQSPHDFIDAICSPGGTTIAGLMELERLGLTTTVSSAI 246
Query: 151 SAAVDRCK 128
+D+ K
Sbjct: 247 DKTIDKAK 254
>UniRef50_A1IB74 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
Pyrroline-5-carboxylate reductase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 280
Score = 107 bits (256), Expect = 4e-22
Identities = 65/187 (34%), Positives = 92/187 (49%), Gaps = 4/187 (2%)
Frame = -3
Query: 661 PSAKNKLFISVAMGITIATVESNLPSEA--RVIRVMPNTPALVKEGAAAFSRGTKATAED 488
P KL I++A GI + T+E L S V+R MPNTPALV G T+ D
Sbjct: 92 PRLSKKLVITIAAGIPVQTIEGMLASAPGLAVVRAMPNTPALVGCGMCGMYANPHVTSAD 151
Query: 487 AQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 311
+ +A G E E +DA+TA+SGSGPAYV+ +E++ G GL A
Sbjct: 152 RGHARAILEATGRVIEFETEALLDAVTAVSGSGPAYVFYFVEAMVKAGENLGLDTKDAFA 211
Query: 310 LAAQTTLGSAA-MVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
+ QT G+ M + G+ P L+ VTSP G+T L + F ++ A+ AA R
Sbjct: 212 MTLQTVKGAVTLMEERGESPKELRQKVTSPGGTTEAALRVLREKEFPEIVMTAIEAACQR 271
Query: 133 CKIVKKQ 113
+ +Q
Sbjct: 272 AGELSRQ 278
>UniRef50_A1H9S1 Cluster: Pyrroline-5-carboxylate reductase; n=6;
Burkholderiales|Rep: Pyrroline-5-carboxylate reductase -
Ralstonia pickettii 12J
Length = 349
Score = 106 bits (255), Expect = 5e-22
Identities = 65/180 (36%), Positives = 92/180 (51%), Gaps = 2/180 (1%)
Frame = -3
Query: 661 PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQ 482
P + L +SVA GI I + L ARV+R MPNTPAL G + + D
Sbjct: 161 PHLGDSLVLSVAAGIRIQDLSRWLNGHARVVRAMPNTPALSGLGMTGLAANAGLSDADRA 220
Query: 481 LTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 305
S + AVG VP E Q+DA+TA+SGSGPAYV+ IE++ GL + LA
Sbjct: 221 TASAIANAVGKSVWVPAEAQIDAVTAISGSGPAYVFYFIEAMQQAAQELGLSAEDGRTLA 280
Query: 304 AQTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
+T +G+A + P +L++ VTS G+T +E ++A + A+ AA R K
Sbjct: 281 VETFIGAATLAGQSSEPVEVLRERVTSKGGTTYAALTSMEGADIKAAFVRAMHAAAARGK 340
>UniRef50_Q1YVF3 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Gammaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - gamma proteobacterium HTCC2207
Length = 271
Score = 106 bits (254), Expect = 7e-22
Identities = 65/184 (35%), Positives = 97/184 (52%), Gaps = 4/184 (2%)
Frame = -3
Query: 673 IKNLPSAKNK--LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
+K+L S+ N + +SVA GI + + L + ++RVMPNTP++V+ GAA
Sbjct: 78 VKDLASSINPGAVVVSVAAGIQLCNFQDWLGASRAIVRVMPNTPSMVRCGAAGLFANALV 137
Query: 499 TAEDAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
+ E +F AVG +C E Q+DA+TA+SGSGPAY ++ +E++ G GL
Sbjct: 138 SNEQKVSIESIFNAVGISCWVDNEAQIDAVTAVSGSGPAYFFLFMETMQRVGQELGLSEQ 197
Query: 322 LALRLAAQTTLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+A L QT LG+A M +H L+ V+SP G+T E I A+ A
Sbjct: 198 VARELTIQTALGAAEMASNSEHNTEELRLQVSSPGGTTRAAIAQFEALDIEETIRQAMRA 257
Query: 145 AVDR 134
A +R
Sbjct: 258 AHNR 261
>UniRef50_Q1PLB2 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=8; Prochlorococcus marinus|Rep: Delta
1-pyrroline-5-carboxylate reductase - uncultured
Prochlorococcus marinus clone ASNC1092
Length = 270
Score = 106 bits (254), Expect = 7e-22
Identities = 57/176 (32%), Positives = 97/176 (55%), Gaps = 1/176 (0%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
K+ L +S+ G++I + P+ + +RV+ N P + +G G + T + Q T
Sbjct: 93 KDNLIVSILAGVSINRLSKKFPNH-KCVRVVTNIPITIGKGLTGICWGEEITEDQKQFTK 151
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
+LF+ E PE +D AL+ SGPA + ++IE+L+DGG+ GLP+ ++ L +
Sbjct: 152 KLFENTSKIYEFPEDYLDIFLALTSSGPAIIALIIEALSDGGLSGGLPKIISEELVMEMI 211
Query: 292 LGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
LG+ ++K + LK+ VTSP G+T LEK RSA++ ++ +A +R K
Sbjct: 212 LGTICLLKENKLTTSELKNLVTSPGGTTISALRILEKKSVRSALMESIVSASNRSK 267
>UniRef50_Q5NMY3 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Zymomonas mobilis|Rep: Pyrroline-5-carboxylate reductase
- Zymomonas mobilis
Length = 284
Score = 105 bits (252), Expect = 1e-21
Identities = 59/153 (38%), Positives = 82/153 (53%), Gaps = 1/153 (0%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
IS+ G+ + T+ P ++R MPN P + +G A K T E + +L
Sbjct: 102 ISILAGVELETLRHFFPKAKSIVRAMPNLPVALGKGVVALC-ADKLTDEQRKCIEKLAST 160
Query: 457 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 278
+G + V E Q D TAL+G GPA+VY I++LA G + GL D AL +A T G+A+
Sbjct: 161 LGIFEWVNENQFDTATALAGCGPAFVYRFIDALAQAGQKLGLTADQALPMAIATVEGAAS 220
Query: 277 MVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKN 182
M K D PA L D V SP GST +G L+K+
Sbjct: 221 MAKQADITPAELADKVASPGGSTRKGMDVLDKD 253
>UniRef50_A4SZT4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Polynucleobacter sp. QLW-P1DMWA-1|Rep:
Pyrroline-5-carboxylate reductase - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 289
Score = 105 bits (251), Expect = 2e-21
Identities = 64/185 (34%), Positives = 94/185 (50%), Gaps = 2/185 (1%)
Frame = -3
Query: 658 SAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQL 479
SA L +S+A GI + + L R +R MPNTPAL+ +G D L
Sbjct: 103 SAPGPLILSIAAGIRLKDMSRWL-DHTRCVRAMPNTPALIGKGITGLFADAAVGQSDRTL 161
Query: 478 TSQLFKAVGTCDEVPEYQ-MDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAA 302
+ AVG V E MDA+TA+SGSGPAYV+ IE++ G + GL A +LA
Sbjct: 162 AETICNAVGQSVWVSEENLMDAVTAVSGSGPAYVFAFIEAMQSAGEKLGLDEKTARKLAY 221
Query: 301 QTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKI 125
T G+ + D H +L++ VTS G+TA ++++G+ + A+ AA R K
Sbjct: 222 ATLEGATQLAHNSDEHAGVLRERVTSKGGTTAAALDVMKQHGWNEILEKAIDAASQRGKT 281
Query: 124 VKKQL 110
+ +L
Sbjct: 282 MGDEL 286
>UniRef50_Q9KEG5 Cluster: Pyrroline-5-carboxylate reductase; n=11;
Bacillus|Rep: Pyrroline-5-carboxylate reductase -
Bacillus halodurans
Length = 267
Score = 104 bits (250), Expect = 2e-21
Identities = 64/190 (33%), Positives = 97/190 (51%), Gaps = 3/190 (1%)
Frame = -3
Query: 688 PALKE--IKNL-PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAF 518
PA E +K L P +L I+VA GI +E++LP +MPNT A V E + +
Sbjct: 74 PAAHENVLKKLSPICNGQLVITVAAGIGPTDLETHLPKGTPTAWIMPNTAASVGESMSIY 133
Query: 517 SRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRC 338
G D QL S + A+G +++ E Q+ +TA++GS PA++Y L E+L
Sbjct: 134 CFGQHVKERDKQLISFILDAIGMSEQLTESQIHHLTAITGSAPAFLYFLAEALEQSAQSY 193
Query: 337 GLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 158
G+ + A L GSA M++ P L++ VT+P G+TA G L + F+ A+
Sbjct: 194 GVAPEKARELVIGMITGSAKMLEEYKDPTQLREQVTTPGGATAAGLQSLLHDDFQGALQR 253
Query: 157 AVSAAVDRCK 128
AV A R +
Sbjct: 254 AVQATNGRAQ 263
>UniRef50_A2QNB5 Cluster: Catalytic activity: L-proline + NAD(P)(+)
<=> 1-pyrroline-5- carboxylate + NAD(P)H; n=1;
Aspergillus niger|Rep: Catalytic activity: L-proline +
NAD(P)(+) <=> 1-pyrroline-5- carboxylate + NAD(P)H -
Aspergillus niger
Length = 304
Score = 104 bits (250), Expect = 2e-21
Identities = 65/187 (34%), Positives = 96/187 (51%), Gaps = 13/187 (6%)
Frame = -3
Query: 661 PSAKNKLFISVAMGITIATVESNL--PSEA--RVIRVMPNTPALVKEGAAAF-------- 518
P++ KL IS+A G T++++ L P E+ ++R +PN A + + A
Sbjct: 99 PTSSPKLLISIAAGWTVSSLRELLSPPQESILYILRALPNICATISQSITAIELPSEEVQ 158
Query: 517 -SRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVR 341
S T+ LT +F +G +V QMD T L GS PA++ + +E+L DGGV
Sbjct: 159 LSARTRVPQALISLTEGIFSRIGRTVQVRADQMDTFTVLGGSTPAFIAVFVEALVDGGVA 218
Query: 340 CGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAII 161
GL R+ A AQ G+ ++ G+HPA+LK+ TSP G T G LE+ GFR +
Sbjct: 219 MGLGREEARMTVAQVLRGTGDLLLGGEHPALLKERGTSPGGCTMGGLCVLEEGGFRGLVG 278
Query: 160 GAVSAAV 140
AV V
Sbjct: 279 RAVREGV 285
>UniRef50_A7D089 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Opitutaceae bacterium TAV2|Rep: Pyrroline-5-carboxylate
reductase - Opitutaceae bacterium TAV2
Length = 150
Score = 104 bits (249), Expect = 3e-21
Identities = 58/144 (40%), Positives = 77/144 (53%), Gaps = 1/144 (0%)
Frame = -3
Query: 562 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 383
MPNTP + G + D L + + ++G E+ E Q+DA+T LSGSGPAY
Sbjct: 1 MPNTPGAIGAGITGWCSLHPLADADRTLVTNILNSLGKHVELAETQLDAVTGLSGSGPAY 60
Query: 382 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAE 206
V+ +L + G+ GLPRD A LA +T LGSA M +TG P L++ VTSP G+T
Sbjct: 61 VFEFAAALREAGIAAGLPRDTAQLLAIETLLGSARLMSQTGTEPETLRNQVTSPNGTTYA 120
Query: 205 GTYHLEKNGFRSAIIGAVSAAVDR 134
G + FR I V AA R
Sbjct: 121 GLQRMAARDFRGLIQETVLAAKTR 144
>UniRef50_A5FLP2 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Flavobacterium|Rep: Pyrroline-5-carboxylate reductase -
Flavobacterium johnsoniae UW101
Length = 258
Score = 104 bits (249), Expect = 3e-21
Identities = 62/180 (34%), Positives = 90/180 (50%), Gaps = 1/180 (0%)
Frame = -3
Query: 664 LPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDA 485
LP +NK S G+++ ++S +E V+R+MPN A E A S K E+A
Sbjct: 79 LPVIQNKTIASAVSGLSLDILQSKTNNEYPVVRIMPNIAAQFGESATCISFPEKYK-ENA 137
Query: 484 QLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 305
LF+ +GT + E MDA T L G AY I + G+ G + AL +A
Sbjct: 138 APIVDLFQDLGTAPVIDEKLMDAATVLGACGTAYALRYIRASMQAGIEIGFDSNTALAIA 197
Query: 304 AQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
AQT G+A M ++ HP L D VT+P G T G +E NGF S++I + ++ + K
Sbjct: 198 AQTVKGAAKMLLEERVHPEQLIDRVTTPQGCTIVGLNEMEHNGFSSSLIKGIKTSLKQIK 257
>UniRef50_Q7VYN6 Cluster: Pyrroline-5-carboxylate reductase; n=45;
Proteobacteria|Rep: Pyrroline-5-carboxylate reductase -
Bordetella pertussis
Length = 277
Score = 103 bits (248), Expect = 3e-21
Identities = 68/178 (38%), Positives = 95/178 (53%), Gaps = 6/178 (3%)
Frame = -3
Query: 643 LFISVAMGITIATVESNL--PSEA--RVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
L +SVA GI T+ L P + R++R MPNTPALV G + T +D +L
Sbjct: 92 LIVSVAAGIRADTLAGWLGEPGQPWQRLVRCMPNTPALVGAGMTGLAALPGVTPQDRELA 151
Query: 475 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
QL +VG V + +DA+TALSGSGPAYV++ IE+L GG GL + A +LA
Sbjct: 152 GQLLTSVGEVVWVDGDAGLDAVTALSGSGPAYVFLFIEALIAGGRAVGLTDEQARQLALG 211
Query: 298 TTLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
T G+ + D PA+L++ VTS G+TA + F + A+ AA R +
Sbjct: 212 TLAGATRLAAQSDEPPAVLRERVTSKGGTTAAALDVYAQGDFAGLVERAMQAAARRSR 269
>UniRef50_Q6LML8 Cluster: Pyrroline-5-carboxylate reductase; n=7;
Gammaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Photobacterium profundum (Photobacterium sp.
(strain SS9))
Length = 272
Score = 103 bits (248), Expect = 3e-21
Identities = 58/181 (32%), Positives = 96/181 (53%), Gaps = 3/181 (1%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
NKL IS+A GI+ + + L +E ++RVMPNTP+L+ +G + + D Q
Sbjct: 90 NKLVISIAAGISASRLNEMLNTELNLVRVMPNTPSLIGKGMSGLFASQSVSENDKVYAEQ 149
Query: 469 LFKAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
L +AVG C E ++ + A +GS PAY ++ +E++ ++ G D A L Q+
Sbjct: 150 LMQAVGEACWVQQESGINGVIAAAGSAPAYFFLFMEAMQKEAIKQGFDADTARLLVQQSA 209
Query: 292 LGSAAMVKTGDHPAM--LKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 119
LG+A +VK + L++ VTS G+TAE ++ + A+ AAV R + ++
Sbjct: 210 LGAAELVKANPETELSTLREQVTSKGGTTAEAIRTFNEHQLSDIVAKAMRAAVSRAEEME 269
Query: 118 K 116
K
Sbjct: 270 K 270
>UniRef50_A4XKQ2 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Pyrroline-5-carboxylate reductase - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 260
Score = 103 bits (248), Expect = 3e-21
Identities = 61/188 (32%), Positives = 99/188 (52%), Gaps = 1/188 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L++IK++ +K+ +S+A GI++ ++ ++ +++RVMPN V+EG
Sbjct: 75 LRKIKDVVG--DKIIVSIAAGISVERIK-DVVGNKKIVRVMPNININVEEGILGVCFSES 131
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
E+ ++LFK++G V E MDAITAL GSGPA+V +ES D V+ G +
Sbjct: 132 VLQEEKDKVTELFKSMGAVIVVDEKFMDAITALFGSGPAFVAHFVESYIDATVKLGFSKQ 191
Query: 322 LALRLAAQTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+ L + G+ +K +KD VTSP G+T EG E+ + AII +
Sbjct: 192 ESYDLVLKLFYGTIVNMKNNMLTTHQIKDMVTSPGGTTIEGLIEFERKALKGAIIDGIIK 251
Query: 145 AVDRCKIV 122
A +R K +
Sbjct: 252 AYERSKSI 259
>UniRef50_Q5QY55 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Idiomarina|Rep: Pyrroline-5-carboxylate reductase -
Idiomarina loihiensis
Length = 274
Score = 103 bits (246), Expect = 6e-21
Identities = 63/181 (34%), Positives = 91/181 (50%), Gaps = 2/181 (1%)
Frame = -3
Query: 670 KNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAE 491
+N+ + +KL I++A GI I L R+IRVMPNTP+LV +G +
Sbjct: 86 ENVHNLTDKLIITIAAGIRIPKYREYLGENIRIIRVMPNTPSLVGQGMSGLVTDDSVDEA 145
Query: 490 DAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLAL 314
D ++ F VG T E Q+D + A++GSGPAY + ++SLA G + A
Sbjct: 146 DKNFVTEAFNGVGETLWVSDEDQLDILGAVAGSGPAYFFEFMDSLAKAATELGFDAEKAR 205
Query: 313 RLAAQTTLGSAAMVKTGDHPAM-LKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVD 137
+ QT LG+A M K + L+ VTS GSTA+G + + AV AAV+
Sbjct: 206 AMVQQTCLGAAQMAKESELSLEDLRKQVTSKGGSTAKGVEAYQDSDLHGISEKAVKAAVN 265
Query: 136 R 134
R
Sbjct: 266 R 266
>UniRef50_Q087E8 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Shewanella|Rep: Pyrroline-5-carboxylate reductase -
Shewanella frigidimarina (strain NCIMB 400)
Length = 292
Score = 102 bits (245), Expect = 8e-21
Identities = 57/175 (32%), Positives = 86/175 (49%), Gaps = 2/175 (1%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
KL IS+A G+ AT+ L +VI MPN P + EG G A D L +L
Sbjct: 113 KLVISIAAGVKHATLRQKLHFSPKVICAMPNLPTAIGEGLTGLYAGPDTHANDIALAERL 172
Query: 466 FKAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
+AVG T E QM I A +GS PAY+++ +E++ + GLP ++A + Q+ +
Sbjct: 173 MRAVGETVWLKEESQMSTIVAAAGSSPAYLFLFLEAMEKAAIEQGLPPEIAAKAVLQSAM 232
Query: 289 GSAAMVKTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
G+ +M H A L+ VTSP G+T + + + A++ A R K
Sbjct: 233 GAISMAMNSQHNLASLRHQVTSPKGTTEQAILAFQDGDLDDLVASAMACATTRAK 287
>UniRef50_Q04FB4 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Oenococcus oeni|Rep: Pyrroline-5-carboxylate reductase -
Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 261
Score = 102 bits (244), Expect = 1e-20
Identities = 56/172 (32%), Positives = 95/172 (55%), Gaps = 1/172 (0%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
NKL +SV ++ + LP+ A+++RV+PN A + + G + ED +LT
Sbjct: 84 NKLIVSVLGSTSLKELTEFLPT-AKIVRVLPNVNAEFNNSLTSVAFGQNLSNEDLKLTKN 142
Query: 469 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
+A GT E+ E A +A++GSGPA+V + I++L + G++ G+ +L++A T
Sbjct: 143 FLQAFGTIIELAERDFPAFSAIAGSGPAFVALFIKALQEAGIKQGIDSKESLQIALHTIK 202
Query: 289 GSAA-MVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVD 137
GS ++++G L V SP GSTA+G LE+N F + A+ A ++
Sbjct: 203 GSTENILQSGKTADQLVKKVASPGGSTADGVESLEENHFIETVNNAILATIN 254
>UniRef50_A4R602 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 246
Score = 101 bits (243), Expect = 1e-20
Identities = 58/163 (35%), Positives = 91/163 (55%), Gaps = 7/163 (4%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAED--AQLTSQ 470
+F++ GI + T+ S LP A ++R MPNTPA +++GA A G TA A+ +
Sbjct: 75 VFVTACPGIRVKTLASWLPQNAAIVRTMPNTPACIRQGATAAFAGPTVTAIPGAAEAVAA 134
Query: 469 LFKAVGT--CDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
L + V C E +D ++SGS PAY++ L++++ + GVR GLP D+A L Q+
Sbjct: 135 LIRHVSPSLCFVPTEDLLDVAASVSGSAPAYIFTLMQAMVEAGVRRGLPPDIAASLVKQS 194
Query: 295 TLGSAAM-VKTGDHPAM--LKDNVTSPAGSTAEGTYHLEKNGF 176
GSA + ++TG + L +V P GST++ L + GF
Sbjct: 195 AFGSAGLALQTGQLGCLEKLTSDVCVPGGSTSQAMMVLHEEGF 237
>UniRef50_Q7M801 Cluster: PUTATIVE PYRROLINE-5-CARBOXYLATE
REDUCTASE; n=1; Wolinella succinogenes|Rep: PUTATIVE
PYRROLINE-5-CARBOXYLATE REDUCTASE - Wolinella
succinogenes
Length = 253
Score = 100 bits (240), Expect = 3e-20
Identities = 65/178 (36%), Positives = 98/178 (55%), Gaps = 1/178 (0%)
Frame = -3
Query: 658 SAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQL 479
S + K S+ G++I + +P+++ IR MPN A + A A L
Sbjct: 80 SGEAKGVYSILAGVSIERLREKIPAQS-YIRAMPNMAASLGSSCTALCGDESLKA----L 134
Query: 478 TSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAA 302
S++F +GT + E ++DA TAL+GSGPAY+ ++ E+L D GVR GL R+ + L
Sbjct: 135 ASEIFAPLGTSLWLDKESKIDAATALAGSGPAYLALMAEALMDAGVREGLSREESKALTQ 194
Query: 301 QTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
G A +++ HPA++K+ VTSP G+TAE LE G R +I AV AA+ + K
Sbjct: 195 GLFSGFADLLE-DRHPALIKEEVTSPGGTTAEALALLESKGLRGILIEAVRAALLKAK 251
>UniRef50_Q3ZWQ2 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Dehalococcoides|Rep: Pyrroline-5-carboxylate reductase -
Dehalococcoides sp. (strain CBDB1)
Length = 267
Score = 100 bits (240), Expect = 3e-20
Identities = 62/176 (35%), Positives = 91/176 (51%), Gaps = 2/176 (1%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
A +L IS+ G T++ + L +A V+RVMPNTPA++ G + ++ +
Sbjct: 86 ADKQLVISIIAGATLSKLSGGLAHKA-VVRVMPNTPAMIGMGMSVWTALPSVSPAQKDQA 144
Query: 475 SQLFKAVGT-CDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
+ A+G E +DA TA+SGSGPAY ++ +E L + G + A L +Q
Sbjct: 145 KAILSAMGKEIYTGKETMLDAATAISGSGPAYFFLFMEGLEKAALEMGFTPEEASILVSQ 204
Query: 298 TTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
T GSA K+G L+ NVTSP G+TAE E+ G + II A AA +R
Sbjct: 205 TAAGSAIYAGKSGLALTQLRKNVTSPGGTTAEAIKAFEEAGLEATIIKAAKAAFNR 260
>UniRef50_Q9K1N1 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Neisseria|Rep: Pyrroline-5-carboxylate reductase -
Neisseria meningitidis serogroup B
Length = 263
Score = 99 bits (238), Expect = 6e-20
Identities = 59/179 (32%), Positives = 96/179 (53%), Gaps = 2/179 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L +SVA G+++ T+ L R++RVMPNTP + G + + + D ++ ++
Sbjct: 83 LVLSVAAGLSVGTLSRYLGGTRRIVRVMPNTPGKIGLGVSGMYAEAEVSETDRRIADRIM 142
Query: 463 KAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
K+VG T E +M IT +SGSGPAYV+ L+++L + +R G A L+ T G
Sbjct: 143 KSVGLTVWLDDEEKMHGITGISGSGPAYVFYLLDALQNAAIRQGFDMAEARALSLATFKG 202
Query: 286 SAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 113
+ A+ +TG+ L+ NVTS G+T E ++ AI V A V R + +++Q
Sbjct: 203 AVALAEQTGEDFEKLQKNVTSKGGTTHEAVEAFRRHRVAEAISEGVCACVRRSQEMERQ 261
>UniRef50_Q2S8M4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Hahella chejuensis KCTC 2396|Rep:
Pyrroline-5-carboxylate reductase - Hahella chejuensis
(strain KCTC 2396)
Length = 276
Score = 99 bits (238), Expect = 6e-20
Identities = 56/175 (32%), Positives = 91/175 (52%), Gaps = 2/175 (1%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+ L +S+A G++ +E+ L + V+R MPNTPA V GA+ + + ++
Sbjct: 91 RRPLIVSIAAGVSCEQIEAWLGGDLPVVRCMPNTPAQVHLGASGLYANPRVSEAQREIAD 150
Query: 472 QLFKAVGTCDEVPEYQ-MDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
LF AVG + + + +TALSGSGPAY +M +E++ + GL A LA QT
Sbjct: 151 NLFSAVGIVAWTSKQEDIHTVTALSGSGPAYCFMFMEAMEEAAASLGLNPASARTLAIQT 210
Query: 295 TLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
G+A + ++ + PA LK V SP G+T + E+ ++ + A+ A R
Sbjct: 211 MRGAAELATRSEESPAQLKKRVMSPGGTTEQAIKSFEEQDMKAMVKTAIRKAWGR 265
>UniRef50_Q9FDK7 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Zymomonas mobilis|Rep: Pyrroline-5-carboxylate reductase
- Zymomonas mobilis
Length = 271
Score = 99.5 bits (237), Expect = 7e-20
Identities = 60/177 (33%), Positives = 87/177 (49%), Gaps = 2/177 (1%)
Frame = -3
Query: 658 SAKNK-LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQ 482
+AK K L +S+ G+T+A E L E + R++PNT + + +S D
Sbjct: 89 NAKEKALIVSIVAGVTLAQFEDLLGKERAIARIIPNT---LTDTGLGYSGVVINNQADKA 145
Query: 481 LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAA 302
LT + G C + E +D T GP YVY IE+L D GV GLPRD+A
Sbjct: 146 LTEKFVSGFGKCLFLEESLIDIFTGFGVCGPNYVYYFIEALVDAGVLAGLPRDIAWETTM 205
Query: 301 QTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
+ +GS M++ +G HP L D SPAG + L ++ F + + +V AAV R
Sbjct: 206 ENLVGSVKMLEISGKHPRQLLDINNSPAGVGMNSLFALNQSDFTAGLQNSVLAAVKR 262
>UniRef50_Q21EI2 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Saccharophagus degradans 2-40|Rep:
Pyrroline-5-carboxylate reductase - Saccharophagus
degradans (strain 2-40 / ATCC 43961 / DSM 17024)
Length = 285
Score = 99.5 bits (237), Expect = 7e-20
Identities = 61/188 (32%), Positives = 97/188 (51%), Gaps = 8/188 (4%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEAR------VIRVMPNTPALVKEGAAAFSRGTKATAED 488
N + +SVA GIT ++ + L + A+ V+R MPNTP+ + GA +
Sbjct: 96 NCVVLSVAAGITCQSLANWLATPAQPAENIAVVRTMPNTPSHIGLGACGLFASSAVAQTQ 155
Query: 487 AQLTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 311
+ AVG V E +++ +TA+SGSGPAY +++ E++ D + GL R A +
Sbjct: 156 KDQAQAIMAAVGLAVWVNSEDEINIVTAVSGSGPAYFFLVFEAMIDAAEKMGLDRQTATQ 215
Query: 310 LAAQTTLGSAAMVKTGDHPAM-LKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
L QT LG+A + +T + A+ L+ VTSP G+T E+N R A+ A DR
Sbjct: 216 LTLQTALGAAKLAQTSEDDAVTLRKKVTSPNGTTERAIASFEQNKLRDTFAAAMQACSDR 275
Query: 133 CKIVKKQL 110
+ + +L
Sbjct: 276 AQQLATEL 283
>UniRef50_A0Z2R8 Cluster: Pyrroline-5-carboxylate reductase; n=1;
marine gamma proteobacterium HTCC2080|Rep:
Pyrroline-5-carboxylate reductase - marine gamma
proteobacterium HTCC2080
Length = 275
Score = 99.5 bits (237), Expect = 7e-20
Identities = 60/184 (32%), Positives = 95/184 (51%), Gaps = 3/184 (1%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLP-SEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQL 479
A + +SVA GI+++ ++ L S A V+R MPNTPALV GA+ + T
Sbjct: 90 APETVVMSVAAGISVSALKDQLSNSNAPVVRCMPNTPALVGAGASGLFASPEVTDRQRAG 149
Query: 478 TSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAA 302
+ VGT + E +D +TA+SGSGPAY + +E++ G R GL + A +L
Sbjct: 150 IDAVMGVVGTTVWLEKESHIDVVTAISGSGPAYFFAFMEAMIATGERMGLDHETASQLTL 209
Query: 301 QTTLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKI 125
QT LG+A + P L+ NVTSP G+T +++ + + + A + R +
Sbjct: 210 QTALGAAKLATQQSDPVNELRRNVTSPGGTTERALESFDQDNLEALVNRGMQACLARAQE 269
Query: 124 VKKQ 113
+ K+
Sbjct: 270 MAKE 273
>UniRef50_Q7WJW6 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bordetella|Rep: Pyrroline-5-carboxylate reductase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 264
Score = 99.1 bits (236), Expect = 1e-19
Identities = 66/191 (34%), Positives = 96/191 (50%), Gaps = 5/191 (2%)
Frame = -3
Query: 685 ALKEIKNLPSAK--NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSR 512
A + ++ +P A+ +S+ G+ + L V R MPNTP + +G
Sbjct: 69 AQQALRAVPPARLARACLVSIMAGVPAGALRQALQPPRPVARAMPNTPVMAGQGCTGLYG 128
Query: 511 GTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCG 335
G +LF+AVG V E Q+ A+TALSGSGPAY ++ E+LA G + G
Sbjct: 129 GDDVAPAQRAAIGRLFEAVGAAFWVDTEDQLHAVTALSGSGPAYYHLFSEALAQAGEQLG 188
Query: 334 LPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNG-FRSAII 161
LP LA LAA+T LG+A++ + G A L+ VTSP G+T E+ G R+ +
Sbjct: 189 LPAALARSLAARTALGAASLQCEEGADFAALRREVTSPHGTTHAAIEVFEQAGALRTLVR 248
Query: 160 GAVSAAVDRCK 128
AV A R +
Sbjct: 249 DAVRQAQARSR 259
>UniRef50_Q5WIM0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacillus clausii KSM-K16|Rep: Pyrroline-5-carboxylate
reductase - Bacillus clausii (strain KSM-K16)
Length = 266
Score = 99.1 bits (236), Expect = 1e-19
Identities = 56/178 (31%), Positives = 87/178 (48%)
Frame = -3
Query: 661 PSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQ 482
P + +L I+VA GI + +E+ LP +MPNT A V + ++ G +
Sbjct: 85 PMIRGQLIITVAAGIGPSDMEAQLPEGTAAAWIMPNTAAQVGTSISLYAFGKNVAEKQKL 144
Query: 481 LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAA 302
L ++ A+G +E+ E Q+ +TA++GS PA+VY L + G+ A L
Sbjct: 145 LVKEIVHAIGAGEELSEEQIHDLTAITGSAPAFVYEFALQLEKMALSYGITDKQARHLVK 204
Query: 301 QTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
GS M++TG P L+D VT+P G+T G L + F + + AV A D K
Sbjct: 205 TMLAGSVKMLETGAPPQELRDQVTTPGGATEAGLVSLGNDHFSAMLERAVHAVTDHAK 262
>UniRef50_A5VEU4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Sphingomonas wittichii RW1|Rep: Pyrroline-5-carboxylate
reductase - Sphingomonas wittichii RW1
Length = 268
Score = 99.1 bits (236), Expect = 1e-19
Identities = 68/189 (35%), Positives = 102/189 (53%), Gaps = 6/189 (3%)
Frame = -3
Query: 682 LKEIKNLPSAKN---KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSR 512
L EI L +AK +L +SV G+ T++ ++ ++R MPN P + EG A
Sbjct: 71 LGEIAPLFAAKAGAPRLLLSVLAGVETTTLKDVFGADV-IVRAMPNLPVSIGEGVTALY- 128
Query: 511 GTKATAEDAQLTSQLFKAVGTCDEVPEYQM-DAITALSGSGPAYVYMLIESLADGGVRCG 335
+ A + L ++G + V E ++ DA+TALSG GP +++ IE++A G G
Sbjct: 129 SSDADEGARNEAAGLVASLGLVEWVDEEKLFDAVTALSGCGPGFLFRFIEAMAQAGEALG 188
Query: 334 LPRDLALRLAAQTTLGSAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 158
LP ALRLA T GSA + + + PA+L D V SP GST EG L+++ A++
Sbjct: 189 LPAGQALRLATATVKGSALLAAGSNEGPAVLADRVASPGGSTREGLNVLDRDEALKALMR 248
Query: 157 A-VSAAVDR 134
A +SAA R
Sbjct: 249 ATLSAAAQR 257
>UniRef50_A6VSQ3 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Marinomonas|Rep: Pyrroline-5-carboxylate reductase -
Marinomonas sp. MWYL1
Length = 275
Score = 98.7 bits (235), Expect = 1e-19
Identities = 59/176 (33%), Positives = 86/176 (48%), Gaps = 2/176 (1%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
++LFISVA GI + ++ L V+R MPNTP+ + G +E S+
Sbjct: 89 DQLFISVAAGIELDSLAHWLGKPVAVVRSMPNTPSQLGAGMTGLIANEHTNSEQKNWVSE 148
Query: 469 LFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
LF ++G V E M +T+LSGS PAY + IE++ GL + LA+
Sbjct: 149 LFSSIGNSVWVENEVHMHTVTSLSGSAPAYFFRFIEAMVKNAKEQGLDEATSRELASNAM 208
Query: 292 LGSAAMVKTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
G+A MV D P A L+ N+TSP G+T + E + A+ A V+R K
Sbjct: 209 FGAARMVMELDEPIAQLRKNITSPKGTTEQALLSFEAADIDKIVADAMMACVNRSK 264
>UniRef50_Q8G5S6 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Bifidobacterium|Rep: Pyrroline-5-carboxylate reductase -
Bifidobacterium longum
Length = 266
Score = 97.9 bits (233), Expect = 2e-19
Identities = 58/183 (31%), Positives = 92/183 (50%), Gaps = 4/183 (2%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSE---ARVIRVMPNTPALVKEGAAAFSR 512
+K + + ++K +S+A G + ++ A + +PNTP V +G
Sbjct: 81 IKPVIGAIADEDKFVVSIAAGWDLDKYRDLFGADFNAAHIQCTIPNTPMAVGKGVLVTEA 140
Query: 511 GTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGL 332
T A++ +LF ++ + V M ++G PA+ M IE+L D GV+ GL
Sbjct: 141 DNTLTDTQAEVFERLFSSISLIERVDSAHMGIGMCIAGCAPAFTDMYIEALGDAGVKYGL 200
Query: 331 PRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGA 155
R A RLAA+ G A+ +K HP ++KD V SP G+T +G LE++ FR A+I A
Sbjct: 201 QRATAYRLAAKMVEGVGALYLKNETHPGVMKDAVCSPGGTTIKGVTSLEESAFRGAVIKA 260
Query: 154 VSA 146
V A
Sbjct: 261 VDA 263
>UniRef50_Q0BPP7 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Granulibacter bethesdensis CGDNIH1|Rep:
Pyrroline-5-carboxylate reductase - Granulobacter
bethesdensis (strain ATCC BAA-1260 / CGDNIH1)
Length = 280
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/177 (35%), Positives = 96/177 (54%), Gaps = 3/177 (1%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
A + +F+SV G+T A + L +A ++R MPNTP+ + +G G L
Sbjct: 90 AGHSVFLSVMAGLTQAGLAGILGEQAAIVRSMPNTPSAIGKGFTMAHAGPHVDGAQRSLC 149
Query: 475 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
L +AVGT E ++ A TA+SG GPAYV+++ E L + + GL DLA +A Q
Sbjct: 150 HTLLEAVGTVAWAEQETELLAATAISGGGPAYVFLIAELLENCALEQGLEPDLARSMARQ 209
Query: 298 TTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHL-EKNGFRSAIIGAVSAAVDR 134
T +G+A +++ + A+L+ VTSP G+T + L ++ SA AV AA+ R
Sbjct: 210 TVIGAALLLEREEADAAVLRRAVTSPGGTTEQALKILMAEDALPSAFSRAVKAAIKR 266
>UniRef50_Q0PQR2 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep:
Pyrroline-5-carboxylate reductase - Endoriftia
persephone 'Hot96_1+Hot96_2'
Length = 186
Score = 97.1 bits (231), Expect = 4e-19
Identities = 55/142 (38%), Positives = 80/142 (56%), Gaps = 6/142 (4%)
Frame = -3
Query: 562 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPA 386
MPNTPA+++ GA + +AVG V E Q+DA+TALSGSGPA
Sbjct: 42 MPNTPAMIQAGATGLHASAGVNDAQRNQAESILRAVGLTRWVEDEAQIDAVTALSGSGPA 101
Query: 385 YVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTA 209
Y ++++E++ V GL + A L QT LG+A M +++ D PA L+ VTSP G+T
Sbjct: 102 YFFLVMEAMEAAAVELGLDSESARLLTLQTALGAARMAIESRDAPATLRQKVTSPGGNTE 161
Query: 208 EGTYHLEKNG----FRSAIIGA 155
+ LE+ G F+ A++GA
Sbjct: 162 KALGILEEGGLRDLFKDALLGA 183
>UniRef50_A1W308 Cluster: Pyrroline-5-carboxylate reductase; n=6;
Comamonadaceae|Rep: Pyrroline-5-carboxylate reductase -
Acidovorax sp. (strain JS42)
Length = 288
Score = 97.1 bits (231), Expect = 4e-19
Identities = 60/174 (34%), Positives = 92/174 (52%), Gaps = 2/174 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L +SVA GI ++ L ++ ++R MPNTPALV +G + + L ++
Sbjct: 108 LHLSVAAGIPTDSIARWLDTQ-HIVRAMPNTPALVGKGITGLFARPQVDPQGKALVERVI 166
Query: 463 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
G V E Q+DA+TALSGSGPAYV++ +E++ GV GLP A +LA T G
Sbjct: 167 ATTGQFVWVEAEEQLDAVTALSGSGPAYVFLFLEAMTQAGVDMGLPPAQAYQLAVATFQG 226
Query: 286 SAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
++ + ++ + +L+ VTS G+T HL+ + I A+ AA R K
Sbjct: 227 ASELAARSPESAEVLRQRVTSKGGTTHAAITHLQAAQVPAHFIAAMRAAEARAK 280
>UniRef50_A6NV19 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacteroides capillosus ATCC 29799|Rep:
Pyrroline-5-carboxylate reductase - Bacteroides
capillosus ATCC 29799
Length = 253
Score = 96.3 bits (229), Expect = 7e-19
Identities = 57/180 (31%), Positives = 92/180 (51%), Gaps = 1/180 (0%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+ K +S++ G ++A + LP V+R MPNTP LV +G A ++ E +
Sbjct: 75 RGKGVLSISPGYSLAWLREQLPG-CHVMRAMPNTPLLVGKGCTALAQSGDVPEELFEAVK 133
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
+F + G VPE+ +DA+ A++GS PAY + + +++ G GL D ALR+AA T
Sbjct: 134 AVFSSAGEVFVVPEHLIDAVIAIAGSSPAYFFRMADAMVSAGQSLGLAPDDALRMAALTM 193
Query: 292 LGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 116
G+A M +++G LK V SP G+T + F + A+ V R + + K
Sbjct: 194 EGAARMLLESGKTAGELKRQVCSPGGTTLAALTAFDDYRFEEMVNEAMERCVRRSQELGK 253
>UniRef50_A4BKC4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Reinekea sp. MED297|Rep: Pyrroline-5-carboxylate
reductase - Reinekea sp. MED297
Length = 273
Score = 96.3 bits (229), Expect = 7e-19
Identities = 58/195 (29%), Positives = 92/195 (47%), Gaps = 2/195 (1%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+ + + A L +SV I ++E L +IR MPNTP+LVK+GA +
Sbjct: 78 LQPLADEAQAHQPLLLSVVAAIPATSIERWLGGNLAIIRTMPNTPSLVKQGATGLYANER 137
Query: 502 ATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
T L F +G V E + A+TA +GS PAY + ES+ + GL
Sbjct: 138 VTDAQKSLAETTFAGIGRYSWVDNEADLHAVTATAGSAPAYFFQFAESMQKTALELGLTD 197
Query: 325 DLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
+ L QT LG+A M+ +T A ++ NV SP G+T + + + + A+
Sbjct: 198 AQSRTLIGQTMLGAATMILETDTDIAQMRKNVCSPNGTTERAIQSFQTDDIDAVVRRAML 257
Query: 148 AAVDRCKIVKKQLND 104
A ++R + + +L D
Sbjct: 258 ACLERSEELSSELGD 272
>UniRef50_Q5ZTZ3 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Legionella pneumophila|Rep: Pyrroline-5-carboxylate
reductase - Legionella pneumophila subsp. pneumophila
(strain Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 262
Score = 95.9 bits (228), Expect = 9e-19
Identities = 55/147 (37%), Positives = 78/147 (53%), Gaps = 2/147 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L ISVA G+++ V+R MPNTPA+V A + + + QLF
Sbjct: 84 LLISVAAGLSLTWFAKYCKKGQAVVRTMPNTPAIVGFAATSMIANEFVNEKQKKWAEQLF 143
Query: 463 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
++G D V E MD +TALSGSGPAYV++ +E++ + GV+ GL +A A QT G
Sbjct: 144 SSIGITDWVKDEEDMDTLTALSGSGPAYVFLFLEAMINAGVQLGLEETVAKHFAIQTFSG 203
Query: 286 SAAMVKTGD-HPAMLKDNVTSPAGSTA 209
S + + L+ VTSP G+TA
Sbjct: 204 SLQLAQHSQLSLTELRKKVTSPGGTTA 230
>UniRef50_A6QB49 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Epsilonproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Sulfurovum sp. (strain NBC37-1)
Length = 252
Score = 94.7 bits (225), Expect = 2e-18
Identities = 65/186 (34%), Positives = 99/186 (53%), Gaps = 1/186 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
++E+ K ++ SV G ++ ++ ++ S+A V+R MPN A V + G
Sbjct: 71 VEEVGKQLKGKARVLFSVLAGTSLEKLKKHIKSKA-VVRAMPNLAASVGASMTTLT-GDH 128
Query: 502 ATAEDAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
+A+ L AVG T E ++D TAL+GSGPAY+ ++ E+LADG V+ GL R
Sbjct: 129 RFQREAE---SLLGAVGDTLWLNSEKEIDIATALAGSGPAYLALVAEALADGAVKQGLKR 185
Query: 325 DLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+ A+ G +++ HPA+LKD V SP G+TA G LE+ RSA + A+
Sbjct: 186 EDAMAAMRGLFNGFGKLIQE-VHPALLKDGVMSPGGTTAAGYGALEEGNVRSACMDAIEE 244
Query: 145 AVDRCK 128
A R K
Sbjct: 245 AYKRAK 250
>UniRef50_A7EEE1 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 326
Score = 94.7 bits (225), Expect = 2e-18
Identities = 55/177 (31%), Positives = 92/177 (51%), Gaps = 7/177 (3%)
Frame = -3
Query: 649 NKLFISVAMGITIATVES---NLPSEAR---VIRVMPNTPALVKEGAAAFSRGTKATAED 488
NKL ISV G T ++ N S+ + +R MPN A +KE + S G++ +
Sbjct: 141 NKLIISVLAGSTTEQLKEFAFNGSSDTKGCSFVRSMPNLGAQIKESSTVISTGSETISSK 200
Query: 487 AQLTSQ-LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 311
+ + +F+++G VP+ L+G PA+ + + DG V G+ RD A
Sbjct: 201 HEKAMEWIFQSIGQYTYVPDNVFQVAGVLAGCTPAWFLTAFDGILDGAVSEGMKRDTAKE 260
Query: 310 LAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAV 140
+ A + L +A +++ G+HPA+L++ V+SP G+T +G +EK G RS A +V
Sbjct: 261 ILAGSMLAAAKLIQNGEHPAVLREKVSSPKGTTIQGLKTIEKGGVRSTYCDATIDSV 317
>UniRef50_A6RSV4 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 314
Score = 94.7 bits (225), Expect = 2e-18
Identities = 56/177 (31%), Positives = 92/177 (51%), Gaps = 7/177 (3%)
Frame = -3
Query: 649 NKLFISVAMGITIATVES---NLPSEAR---VIRVMPNTPALVKEGAAAFSRGTKATAED 488
NKL ISV G T ++ N S+ + +R MPN A +KE + S GT+ +
Sbjct: 129 NKLVISVLAGSTTEQLKEFAFNGSSDTKGCAFVRSMPNLGAQIKESSTVISTGTETISPK 188
Query: 487 AQLTSQ-LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 311
+ + +F+++G VP+ L+G PA+ + + DG V G+ RD A
Sbjct: 189 YEEAMKWIFQSIGQYTYVPDNVFQVAGVLAGCTPAWFLTAFDGILDGAVSEGMRRDTATE 248
Query: 310 LAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAV 140
+ A + L +A +++ G+HPA+L++ V+SP G+T +G +EK G RS A +V
Sbjct: 249 ILAGSMLAAAKLIQNGEHPAVLREKVSSPKGTTIQGLKTIEKGGVRSTYCDATIDSV 305
>UniRef50_A7BDU0 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 268
Score = 94.3 bits (224), Expect = 3e-18
Identities = 56/172 (32%), Positives = 93/172 (54%), Gaps = 6/172 (3%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF-- 464
+S+A G T+ + ++ + ++RVMPN A V + A T A A DAQ+ + F
Sbjct: 93 VSLAAGRTLDQITTDFGAGIPLVRVMPNVAATVGQSMTAL---TAARATDAQVAAVRFLM 149
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
++G + E AL+ PA+ + +++S A G++ GL +D A+ +AAQ G+
Sbjct: 150 DSIGRTILIDEDYFPVFQALASCSPAWYFQIVDSFARAGLKHGLSKDSAVEIAAQAMAGA 209
Query: 283 AAMV----KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAV 140
AA++ + G PA L D VTSP G+T G E+ G +A++ AV A++
Sbjct: 210 AALLLAERENGTIPAQLIDRVTSPGGTTIAGLLAAEEGGLSTALVSAVDASI 261
>UniRef50_Q2PIP2 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Trichocomaceae|Rep: Pyrroline-5-carboxylate reductase -
Aspergillus oryzae
Length = 292
Score = 93.9 bits (223), Expect = 4e-18
Identities = 53/184 (28%), Positives = 88/184 (47%), Gaps = 9/184 (4%)
Frame = -3
Query: 652 KNKLFISVAMGIT------IATVESNLP---SEARVIRVMPNTPALVKEGAAAFSRGTKA 500
+ KL +S+ GIT +A E + P S + +R MPN A ++E ++ G+
Sbjct: 104 QGKLVLSIMAGITTKALNILALGEDSAPDNESALQCVRAMPNMAAKIREAVTLYTAGSGT 163
Query: 499 TAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 320
T E+ ++ S +F VG +PE D G + + + I+ L D V G+ R
Sbjct: 164 TKENLEIASWVFSQVGEAHRIPESSFDICAVSVGCAGSLLLLAIDGLLDAAVAEGVKRPD 223
Query: 319 ALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAV 140
L + +G +V GDH ++L++ + SP G + LEK G R+A A+ AA
Sbjct: 224 VQNLVVNSAIGMMKLVPAGDHVSVLREKIASPGGCSIRALLELEKLGVRAAFTTAIMAAA 283
Query: 139 DRCK 128
++ K
Sbjct: 284 EKSK 287
>UniRef50_A2BJN9 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Hyperthermus butylicus DSM 5456|Rep:
Pyrroline-5-carboxylate reductase - Hyperthermus
butylicus (strain DSM 5456 / JCM 9403)
Length = 247
Score = 93.9 bits (223), Expect = 4e-18
Identities = 60/181 (33%), Positives = 97/181 (53%), Gaps = 2/181 (1%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
K +SV G+ ++ ++ L A V R MPN ++ G + + + A L +
Sbjct: 58 KPVVSVMAGVPVSLLQKVLKG-AEVYRAMPNLN--IRVGRSLTALYSPPNARHYGLVRRA 114
Query: 466 FKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
GT +VPE +DA TA++GSGPA V +++L + GLPR +A R+AA+
Sbjct: 115 LSCFGTVYDVPEEFIDAWTAVAGSGPALVAEFLDALVLAALAVGLPRSIARRVAAELLES 174
Query: 286 SAA-MVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 113
+A +++ D HP +L+D V +PAG+T LE GF+SA+I AV A R + ++
Sbjct: 175 TARYLLENPDVHPGVLRDEVITPAGTTIAAIRTLESRGFKSAVIDAVRDATLRAGEIARE 234
Query: 112 L 110
+
Sbjct: 235 I 235
>UniRef50_Q5ZP97 Cluster: Pyrroline carboxylate reductase-like
protein; n=1; Angiococcus disciformis|Rep: Pyrroline
carboxylate reductase-like protein - Angiococcus
disciformis
Length = 358
Score = 93.5 bits (222), Expect = 5e-18
Identities = 64/178 (35%), Positives = 94/178 (52%), Gaps = 3/178 (1%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQL-T 476
++ + +S+ G + T+ L V+R MPNTPA V++ AA F + +E A +
Sbjct: 167 EDTIVVSIIAGARLQTLCEGL-EHPLVVRAMPNTPARVRK-AATFWIPSAGLSEPALVRV 224
Query: 475 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
L A+GT EV E ++ T L+G PA+VY LIE+ D GV GLPRD A +
Sbjct: 225 RSLLGALGTEVEVADEAGVEMATGLAGPMPAFVYFLIEAFIDAGVALGLPRDQATLATVE 284
Query: 298 TTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
+ GS ++ ++ + PA L+ VTSP G+T G E G R A+ AV A R +
Sbjct: 285 SMRGSLELLHRSQESPAALRKQVTSPGGATLAGLKVFESAGVRDAMDAAVRAVHARAQ 342
>UniRef50_UPI0000E87E64 Cluster: pyrroline-5-carboxylate reductase;
n=1; Methylophilales bacterium HTCC2181|Rep:
pyrroline-5-carboxylate reductase - Methylophilales
bacterium HTCC2181
Length = 269
Score = 92.7 bits (220), Expect = 9e-18
Identities = 55/173 (31%), Positives = 94/173 (54%), Gaps = 2/173 (1%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQL 467
+L IS+A GI+I + L + ++R MPN A ++ A + + + +
Sbjct: 90 QLIISIAAGISIKNISKWLGNYKHIVRTMPNLVAQIQRSMTALCGAEELSQDHKNDAQSI 149
Query: 466 FKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
F +G + E+++DA+T++SGSGPAYV+ ++SL + G + GL RD A LA +T +
Sbjct: 150 FNTIGKILWLNDEFKIDAVTSISGSGPAYVFYFLDSLIEAGEKVGLSRDEAEYLAHETLI 209
Query: 289 GSAAMVKTG-DHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
GSA M ++ + L +NV+S G+T + L+ + I AV++A R
Sbjct: 210 GSAIMSESYLNDLGTLINNVSSKGGTTEQAISVLKNKDLKEIIGLAVASAFKR 262
>UniRef50_Q9AAU9 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Caulobacter|Rep: Pyrroline-5-carboxylate reductase -
Caulobacter crescentus (Caulobacter vibrioides)
Length = 260
Score = 92.7 bits (220), Expect = 9e-18
Identities = 64/179 (35%), Positives = 93/179 (51%), Gaps = 3/179 (1%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAA-FSRGTKATAEDAQL 479
A + + +S+A G+ A + RV RVMP T + +GAA+ ++ +A A L
Sbjct: 82 APDAVIVSIAAGVRAADISQAFGGR-RVARVMPTTAVAIGQGAASLYADDAEALARARAL 140
Query: 478 TSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
+ L + E M A TA+SGS PAY+Y IE+L G GL + RLA
Sbjct: 141 FAPL---AAVAELASEDLMHAATAVSGSAPAYLYAFIEALEAAGAAQGLDPAQSARLARA 197
Query: 298 TTLGSAA-MVKTGDHPAMLKDNVTSPAGSTAEG-TYHLEKNGFRSAIIGAVSAAVDRCK 128
T +G+AA M ++G+ PA L+ VTSP G+TA + + GF + A+ AAV R K
Sbjct: 198 TIIGAAALMAQSGEEPAELRKQVTSPGGTTAAALSVLMGAGGFGDLLPKALDAAVARSK 256
>UniRef50_Q5HFR9 Cluster: Pyrroline-5-carboxylate reductase; n=16;
Staphylococcus|Rep: Pyrroline-5-carboxylate reductase -
Staphylococcus aureus (strain COL)
Length = 271
Score = 92.3 bits (219), Expect = 1e-17
Identities = 54/174 (31%), Positives = 84/174 (48%), Gaps = 1/174 (0%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
K+ FIS+ GI I ++ L + V R+MPNT A V S + +
Sbjct: 88 KDNCFISIMAGIPIDYIKQQLECQNPVARIMPNTNAQVGHSVTGISFSNNFDPKSKDEIN 147
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
L KA G+ EV E + +TA++GSGPA++Y + E G + GL ++
Sbjct: 148 DLVKAFGSVIEVSEDHLHQVTAITGSGPAFLYHVFEQYVKAGTKLGLEKEQVEESIRNLI 207
Query: 292 LGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
+G++ M++ D A L+ N+TS G+T G L + S ++AAVDR
Sbjct: 208 IGTSKMIERSDLSMAQLRKNITSKGGTTQAGLDTLSQYDLVSIFEDCLNAAVDR 261
>UniRef50_UPI00015BCA3C Cluster: UPI00015BCA3C related cluster; n=1;
unknown|Rep: UPI00015BCA3C UniRef100 entry - unknown
Length = 247
Score = 91.9 bits (218), Expect = 2e-17
Identities = 54/187 (28%), Positives = 102/187 (54%), Gaps = 2/187 (1%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L +K L + K +S+ GI+++ ++ ++ +A + R+MPN + K+G F
Sbjct: 68 LTSLKGL-NFNEKSLVSMLAGISVSRLKEHI-KDAYITRIMPNLAVIYKKGVIGFY---- 121
Query: 502 ATAEDAQ--LTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
+EDA+ + + + +G E+ E DA TA+ GSGPA++ ++E++ G+ GL
Sbjct: 122 --SEDAKKDVIKSILQHLGKVYELDEKHFDAFTAIGGSGPAFIASVVEAMRLSGIYMGLN 179
Query: 328 RDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
+D++ LA T G+ ++K + ++ V+SPAG+T EG Y++EK G + ++
Sbjct: 180 KDISYDLAIATIEGTLEILKAYNEEELVL-KVSSPAGTTIEGIYNIEKTGLKGILMETFI 238
Query: 148 AAVDRCK 128
A + K
Sbjct: 239 KAYQKSK 245
>UniRef50_Q0UG51 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 291
Score = 91.9 bits (218), Expect = 2e-17
Identities = 53/177 (29%), Positives = 93/177 (52%), Gaps = 3/177 (1%)
Frame = -3
Query: 673 IKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATA 494
I++ A + +++ GITI+ +++ LP+ +IR MPNTP V +GA A T+
Sbjct: 102 IESFCKANPPVVLTMCPGITISQLQTWLPANYPIIRSMPNTPVAVGQGATALFANKFVTS 161
Query: 493 EDAQLTSQLFKAVGTCDEVPEYQ--MDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 320
++F V C E + +D + ++SGSGPAY++ + +++ D + GLP
Sbjct: 162 GSINEIKKVFLNVSPCVECLNCEDLLDVVASVSGSGPAYLFYMAQAIVDAAIAKGLPEKQ 221
Query: 319 ALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
A L Q+ +G++ + + + L D+V P GST + L+ +G AI+ AV
Sbjct: 222 AKSLVIQSVIGASLLAQRMPQSLSELLDDVCVPGGSTEKAMATLDLHGANDAILKAV 278
>UniRef50_Q0CFR0 Cluster: Predicted protein; n=3; Aspergillus|Rep:
Predicted protein - Aspergillus terreus (strain NIH
2624)
Length = 304
Score = 91.9 bits (218), Expect = 2e-17
Identities = 55/169 (32%), Positives = 87/169 (51%), Gaps = 1/169 (0%)
Frame = -3
Query: 631 VAMGITIATVESNLPSEAR-VIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAV 455
+A I A+ ++ S+AR ++R MPN A +++ +AE A L + +F+ V
Sbjct: 136 IAACIDHASPTADAGSDARNIVRAMPNVAARLRQSMTIIEADPALSAERAALLTWMFEQV 195
Query: 454 GTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAM 275
G V Q DA L G+ A + ++ L DG V G+ R A +AAQ G AA+
Sbjct: 196 GHVKYVAAEQFDAAGMLVGASMAMFTVPLDGLLDGCVVEGIRRPEAQEMAAQVLQGMAAL 255
Query: 274 VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
+K G HPA+L++++ SP G T +G +E+ G R+A + D K
Sbjct: 256 LKDGAHPAVLRESIASPRGCTIQGLMTVERRGVRAAFADGMIDGTDHLK 304
>UniRef50_Q03V33 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Leuconostoc mesenteroides subsp. mesenteroides ATCC
8293|Rep: Pyrroline-5-carboxylate reductase -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 255
Score = 91.5 bits (217), Expect = 2e-17
Identities = 52/183 (28%), Positives = 92/183 (50%), Gaps = 1/183 (0%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+ + N + K+ ISV +TIA ++ P+ V R +PN + + +G+ A + +
Sbjct: 70 LRTLGNSLNLDGKIVISVLAQVTIADLDEVFPTAFNV-RSLPNINSAIGKGSTALAFSKR 128
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
++ + +GT + E +A++GSGPA+V I++L G+ GL +
Sbjct: 129 LNEGQIEVVQNYWHLLGTTSVLDEQHFAIFSAIAGSGPAFVLKFIDALTQAGINNGLDGE 188
Query: 322 LALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
A +AA T G+ + K+ L +NV SP GST G + E+N F + + A++A
Sbjct: 189 SAAAIAASTVAGTTETLQKSNSDAVTLMNNVASPGGSTRAGLDNFEQNDFDTIVNSAINA 248
Query: 145 AVD 137
V+
Sbjct: 249 TVN 251
>UniRef50_UPI0000E1F031 Cluster: PREDICTED: similar to
Pyrroline-5-carboxylate reductase family, member 2
isoform 1; n=2; Catarrhini|Rep: PREDICTED: similar to
Pyrroline-5-carboxylate reductase family, member 2
isoform 1 - Pan troglodytes
Length = 253
Score = 91.1 bits (216), Expect = 3e-17
Identities = 67/175 (38%), Positives = 88/175 (50%), Gaps = 3/175 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPS---EARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+ +S A G+TI++VE L + +VIR M NTP +V+EGA ++ GT A ED QL
Sbjct: 55 IVVSCAAGVTISSVEKKLMAFQPAPKVIRCMTNTPVVVREGATVYATGTHALVEDGQLLE 114
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
QL +VG C EV E D I A++G L+ G G AA+
Sbjct: 115 QLMSSVGFCTEVEE---DLIDAVTG------------LSGSGPAYG---------AAKML 150
Query: 292 LGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
L S HP LKDNV SP G+T + LE GFRS +I AV A+ R +
Sbjct: 151 LDSE------QHPCQLKDNVCSPGGATIHALHFLESGGFRSLLINAVEASCIRTR 199
>UniRef50_Q8A6I2 Cluster: Pyrroline-5-carboxylate reductase; n=6;
Bacteroides|Rep: Pyrroline-5-carboxylate reductase -
Bacteroides thetaiotaomicron
Length = 266
Score = 91.1 bits (216), Expect = 3e-17
Identities = 50/172 (29%), Positives = 89/172 (51%), Gaps = 1/172 (0%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
++ ++ +S+ GI+I+ + +E + RV+PN A+ + + KA E QL
Sbjct: 85 SRTQILVSLVTGISISHLAHLSETEMPIFRVVPNI-AITEHSSLTLITSRKAGKEHQQLI 143
Query: 475 SQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
Q F+ G C E Q+D I+AL+ SG A+ I + G+ G+ + A+R+ A +
Sbjct: 144 KQTFEEGGKCLFAEEKQLDIISALTSSGIAFALKYIHAAMQAGIELGISAEDAMRMTAYS 203
Query: 295 TLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
G+ ++ D HP + + +P G+T +G LE GF SA+I A+ ++
Sbjct: 204 MEGATELILNHDTHPLLEIEKAATPGGATIKGLNELEHRGFTSAVIHAIKSS 255
>UniRef50_A4A9D5 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=1; Congregibacter litoralis KT71|Rep: Delta
1-pyrroline-5-carboxylate reductase - Congregibacter
litoralis KT71
Length = 272
Score = 89.8 bits (213), Expect = 6e-17
Identities = 56/181 (30%), Positives = 87/181 (48%), Gaps = 2/181 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L ISVA G+T + L S+ V+R MPNTP+ + GA+ + Q ++
Sbjct: 92 LVISVAAGVTADNIHRWLGSKGEVVRCMPNTPSQIGAGASGLYARASVGDANRQRAEEVM 151
Query: 463 KAVGTCDEVPEYQM-DAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
AVG V E + A+TA++GS PAY + +E++ R GL + A L AQT +G
Sbjct: 152 SAVGVVRWVQEEPLLHAVTAVAGSAPAYFFQFMEAMIAEAGRMGLDEESARTLCAQTCIG 211
Query: 286 SAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQL 110
+ M+ GD A L+ V SP G+T G + A+ A R + + ++
Sbjct: 212 AGRMLAEGDVDAAELRRRVCSPNGATERAVDAFSAGGLDKLVSKAMEACAARSEELAQEF 271
Query: 109 N 107
+
Sbjct: 272 S 272
>UniRef50_Q8D3C2 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Wigglesworthia glossinidia endosymbiont of Glossina
brevipalpis|Rep: Pyrroline-5-carboxylate reductase -
Wigglesworthia glossinidia brevipalpis
Length = 291
Score = 89.0 bits (211), Expect = 1e-16
Identities = 55/188 (29%), Positives = 96/188 (51%), Gaps = 4/188 (2%)
Frame = -3
Query: 679 KEIKNLPSAKNKLFISVAMGITIATVESNLPS-EARVIRVMPNTPALVKEGAAAFSRGTK 503
+EIKNL + +NKL ISVA GI I +++ L + +A + R MPNTP LV+EG
Sbjct: 95 EEIKNLTNIENKLIISVAAGININSIKKYLNNKKALIARAMPNTPVLVREGVIGLYAKKD 154
Query: 502 ATAEDAQLTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
+ Q+F +G + E +++ I + S S AY +++++++ + G+ +
Sbjct: 155 IRTIHEKTIEQIFNRIGKIFWLSQEKEINYIISASSSATAYFFLMMDAMKNTAENIGINK 214
Query: 325 DLALRLAAQTTLGSAAMVKTGDHPAM--LKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
+ + QT G+ + + + LK ++TS G+T +KN FR + ++
Sbjct: 215 SYSREVILQTAKGAIVLAEHFSEISFNTLKKHITSKKGTTEAALNSFKKNNFRKIVEISM 274
Query: 151 SAAVDRCK 128
AAV R K
Sbjct: 275 KAAVSRAK 282
>UniRef50_Q1GX51 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Sphingopyxis alaskensis|Rep: Pyrroline-5-carboxylate
reductase - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 286
Score = 88.6 bits (210), Expect = 1e-16
Identities = 56/171 (32%), Positives = 93/171 (54%), Gaps = 3/171 (1%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
+S+ G+++A + + P+ +R++PN A + G +A + +A D + L
Sbjct: 107 LSILAGVSLADLAARFPAAKAQVRILPNLAARIGAGVSAVASSGEA---DMAAVTALLDP 163
Query: 457 VGTCDEVPEYQ-MDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA 281
+GT + + MD +TA +GSGPA+V+ LIES A G R GL + AL+LA T G+
Sbjct: 164 LGTIVALADDSTMDLVTAFTGSGPAFVFRLIESYAAAGERLGLSAEDALKLATATFGGAT 223
Query: 280 AMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAII-GAVSAAVDR 134
A++ +G+ P L V S G+T G L+ +G +A++ + AA DR
Sbjct: 224 ALLADSGEKPGTLIAQVASKGGTTQAGLDVLDSDGQLAALLTNVLRAARDR 274
>UniRef50_A0M2T1 Cluster: Pyrroline-5-carboxylate reductase; n=6;
Flavobacteriaceae|Rep: Pyrroline-5-carboxylate reductase
- Gramella forsetii (strain KT0803)
Length = 268
Score = 88.6 bits (210), Expect = 1e-16
Identities = 53/184 (28%), Positives = 95/184 (51%), Gaps = 2/184 (1%)
Frame = -3
Query: 679 KEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
+E+K++ + K+++F+S+ G+TI ++ L + +V+R MPN PA V +G +++ +
Sbjct: 79 EEMKSMVN-KDQIFVSLMAGVTINKIQEGLGVK-KVVRSMPNLPAQVGKGVTSYTESKEV 136
Query: 499 TAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
+ + + L G V E +DA T +SGSGPAYV+ + S+ + ++ G ++
Sbjct: 137 SRVELLMVRNLLDTTGESIHVENENYIDASTGISGSGPAYVFYFMNSMLEAALKMGFSKN 196
Query: 322 LALRLAAQTTLGSAAMVKTGD-HPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
+ L +QT G+ + D P D V S G+T ++ N + I A A
Sbjct: 197 DSKVLVSQTFEGAVELFNQNDLSPDTWMDRVASKGGTTRAALDSMDDNNVKELIKDAAYA 256
Query: 145 AVDR 134
A DR
Sbjct: 257 AFDR 260
>UniRef50_Q18J37 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Halobacteriaceae|Rep: Pyrroline-5-carboxylate reductase
- Haloquadratum walsbyi (strain DSM 16790)
Length = 258
Score = 88.6 bits (210), Expect = 1e-16
Identities = 60/169 (35%), Positives = 94/169 (55%), Gaps = 1/169 (0%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
++ A G+ + V + ++A VIR+MPN A ++E AAA + A + L+
Sbjct: 86 MTAAAGVERSFVSNQ--TDATVIRLMPNLAASLREMAAAVAWDEPDPAVETMLSD----- 138
Query: 457 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 278
+G+ + E M+ TAL+GSGPA+VY LI+S+ ++ GL + A LA QT +G+A
Sbjct: 139 LGSYVVIDETHMNIATALNGSGPAFVYYLIQSMQTRAIKEGLDKSDAQTLAIQTFIGAAE 198
Query: 277 MVKTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
MV+ D P L D V SP G+T EG L + + + A++AA +R
Sbjct: 199 MVRAADEPIESLIDAVCSPNGTTIEGMNVLFDSNVDAEVGDALTAATER 247
>UniRef50_Q1VVL6 Cluster: Pyrroline-5-carboxylate reductase; n=9;
Bacteroidetes|Rep: Pyrroline-5-carboxylate reductase -
Psychroflexus torquis ATCC 700755
Length = 266
Score = 88.2 bits (209), Expect = 2e-16
Identities = 54/181 (29%), Positives = 88/181 (48%), Gaps = 1/181 (0%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+N + IS G I+ +E + ++ +IR MPNT V + K A+ ++
Sbjct: 85 ENHILISTITGFLISKIEGLVGNDQFIIRAMPNTAIAVGKSMTCLCSNEKG-AKRIKVAE 143
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
+F +G +PE QM A T + SG A+ LI + ++ G A LA T+
Sbjct: 144 AIFNRLGHTLAIPESQMQAATVICASGIAFWMRLIRASTQAAIQLGFDAKEAQELAMYTS 203
Query: 292 LGSAAMVKT-GDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 116
G+A ++ T G HP D VT+P G T EG +E G S++I + A+ ++ +KK
Sbjct: 204 EGAANLLITNGLHPEEEIDRVTTPKGCTIEGLNEMEHKGLSSSLIQGMVASFNKINNIKK 263
Query: 115 Q 113
+
Sbjct: 264 E 264
>UniRef50_Q5FRU8 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Gluconobacter oxydans|Rep: Pyrroline-5-carboxylate
reductase - Gluconobacter oxydans (Gluconobacter
suboxydans)
Length = 259
Score = 87.0 bits (206), Expect = 4e-16
Identities = 65/184 (35%), Positives = 88/184 (47%), Gaps = 8/184 (4%)
Frame = -3
Query: 661 PSAKNKLFISVAMGITIATVESNLP---SEARVIRVMPNTPALVKEGAAAFSRGTKATAE 491
P N +SV G T A + ++ V+R MPNTP+ V G + AT E
Sbjct: 72 PRMSNAAILSVMAGRTCAALSDAARLAGADIPVLRAMPNTPSAVGAGISGLYAAPSATPE 131
Query: 490 DAQLTSQLFKAVGTCDEVP---EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDL 320
+ L AVG D VP E + +TA+SGSGPAYV++L E L G + GL +
Sbjct: 132 QKSICHDLLFAVG--DVVPVEKEADLSVVTAISGSGPAYVFLLAELLEKAGQQHGLSPTI 189
Query: 319 ALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEK-NGFRSAIIGAVSA 146
A RLA T G+ M+ D L+ VTSP G+TA L K + + + A+ A
Sbjct: 190 ARRLARGTIYGAGRMLDDLPDSAEDLRKAVTSPNGTTAAALAVLMKSDAWPETVPKAIDA 249
Query: 145 AVDR 134
A R
Sbjct: 250 ATKR 253
>UniRef50_A7LUS1 Cluster: Putative uncharacterized protein; n=1;
Bacteroides ovatus ATCC 8483|Rep: Putative
uncharacterized protein - Bacteroides ovatus ATCC 8483
Length = 271
Score = 87.0 bits (206), Expect = 4e-16
Identities = 49/173 (28%), Positives = 91/173 (52%), Gaps = 2/173 (1%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAF-SRGTKATAEDAQL 479
++ ++ +S+ G+ I+ + +E + R +PN + SRGT E QL
Sbjct: 85 SRTQILVSLVSGVCISHLAHLTEAEMPIFRAVPNMAITERSSLTLIASRGTDK--EYQQL 142
Query: 478 TSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
Q+F+ G C + E Q+D +AL+ SG A+ ++++ G+ G+P A+++AA
Sbjct: 143 IKQIFEEGGKCLFLQEKQLDTTSALTSSGIAFALKYMQAVMQAGIELGIPGKDAMQMAAY 202
Query: 298 TTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
+ G+ ++ HP + + VT+P G+T +G LE GF S+II A+ ++
Sbjct: 203 SMEGATELILNHNTHPLLEIEKVTTPGGTTIKGLNELEHKGFTSSIIQAIKSS 255
>UniRef50_Q11WK0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Cytophaga hutchinsonii ATCC 33406|Rep:
Pyrroline-5-carboxylate reductase - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 268
Score = 86.2 bits (204), Expect = 7e-16
Identities = 54/177 (30%), Positives = 93/177 (52%), Gaps = 2/177 (1%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+N++ +S+ GI IA +++ L + V+R MPNTPA + G AF+ A+ E+ +
Sbjct: 87 ENQMILSIMAGIQIAQIQTLLEHK-NVVRAMPNTPAQLGFGITAFTVAKDASFENISVVD 145
Query: 472 QLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
L + G + E +DA+TALSGSGPAY Y +++++ + G + G+ ++A L +T
Sbjct: 146 MLLETTGKAIFMKDETMLDAVTALSGSGPAYFYYIVQNMIEAGKQMGVDENVAGMLVKET 205
Query: 295 TLGSAAMVKTGDHPA-MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
+G+ ++ L V S G+T L++ + II A+ A R K
Sbjct: 206 MMGAFQILNHSKSSIDELIAMVASKGGTTEAALNTLKQREVGAHIIEALKNAEKRAK 262
>UniRef50_Q88GE6 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Pseudomonas putida KT2440|Rep: Pyrroline-5-carboxylate
reductase - Pseudomonas putida (strain KT2440)
Length = 264
Score = 85.8 bits (203), Expect = 1e-15
Identities = 57/170 (33%), Positives = 86/170 (50%), Gaps = 2/170 (1%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
+SV GIT AT+ L +A V+R +PNTP+ V +G + + A A Q+F
Sbjct: 90 VSVMAGITHATLVRLLGHDA-VVRAIPNTPSEVAQGVTMYYAPSDADAALIDSARQIFDV 148
Query: 457 VGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA 281
+G V E Q+D TAL+G GPA V ++L D G+ GL + A +A Q G+A
Sbjct: 149 IGLSLRVNDERQIDTGTALAGGGPALVAHFADALQDYGLHMGLDSEQAAVVALQLLSGTA 208
Query: 280 AMVKTGDHPA-MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDR 134
A+++ PA + V + G+T L+ GF+ + A+ AA R
Sbjct: 209 ALIQASGKPASQICQEVQTAGGTTERAIRALDAAGFKGLVNAALDAAARR 258
>UniRef50_Q2NCY1 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Sphingomonadales|Rep: Pyrroline-5-carboxylate reductase
- Erythrobacter litoralis (strain HTCC2594)
Length = 269
Score = 85.8 bits (203), Expect = 1e-15
Identities = 55/155 (35%), Positives = 80/155 (51%), Gaps = 3/155 (1%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTP-ALVKEGAAAFSRGTKATAEDAQLTSQLFK 461
+SV GI +A++ + P V+R MPN AL K G T + + L +
Sbjct: 88 LSVLAGIELASLRARFPQAEGVVRFMPNLACALGKAPNGLIGEGLSDTQRG--MVTDLAE 145
Query: 460 AVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
+G+ + + E + D +TAL+GSGP +VY I++LA G R GL A RLA Q G+
Sbjct: 146 KLGSAEWLEDESRFDLVTALAGSGPGFVYRFIDALAVAGTRLGLDEGQAGRLAIQMVEGA 205
Query: 283 AAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKN 182
AA+ +H P L V SP G T +G L++N
Sbjct: 206 AALAAQSEHSPGELARRVASPGGMTQKGLDVLDEN 240
>UniRef50_Q1U6D2 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Lactobacillus reuteri|Rep: Pyrroline-5-carboxylate
reductase - Lactobacillus reuteri 100-23
Length = 270
Score = 85.4 bits (202), Expect = 1e-15
Identities = 55/176 (31%), Positives = 86/176 (48%), Gaps = 1/176 (0%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
+S+ G+T+A + S A + R++PNT + + A +S K + + +
Sbjct: 95 LSIIAGVTVAQLSSQEDLFA-ITRIIPNT---LTDVAMGYSGVVKNDRANQTVIEDFLNS 150
Query: 457 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 278
G D + E +D T +GP Y+Y + S + GV G+PR A +LA + +AA
Sbjct: 151 FGKVDYIDESLLDVFTGYGVAGPNYIYNFLISFTNAGVLAGMPRQQANKLALENLRAAAA 210
Query: 277 MV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 113
V ++G HPA L D S G + L+K+ F + I AV AAV R K + KQ
Sbjct: 211 FVEQSGKHPAELLDINNSAGGVGITAQHELDKSSFSAGIENAVLAAVKRTKELGKQ 266
>UniRef50_Q4HSX5 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Campylobacter|Rep: Pyrroline-5-carboxylate reductase -
Campylobacter upsaliensis RM3195
Length = 244
Score = 84.6 bits (200), Expect = 2e-15
Identities = 56/179 (31%), Positives = 94/179 (52%), Gaps = 1/179 (0%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
AL E+ + + ++ ISV ++ +E + R+MPN A K F
Sbjct: 67 ALNEMSQILKGEARILISVLANTSLKELECIRAQN--IARIMPNIAAKYKASTTPFILKN 124
Query: 505 KATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
+ E+ Q+ + G E+ E QM + ALSG PA++ ++ E+LA+GGV GL
Sbjct: 125 ELFKEEI---IQILTSFGNAYELSSEKQMPSAMALSGCAPAFLSLVAEALANGGVYRGLD 181
Query: 328 RDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
++L+L+L Q S + + +HPA++K++V SPAG + +G LE+ R+A + AV
Sbjct: 182 KELSLKL-TQGLFESFSTLLAHEHPALIKESVCSPAGVSIKGVKVLEERAIRAAFMEAV 239
>UniRef50_A3X4C4 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Roseobacter sp. MED193|Rep: Pyrroline-5-carboxylate
reductase - Roseobacter sp. MED193
Length = 224
Score = 83.8 bits (198), Expect = 4e-15
Identities = 50/122 (40%), Positives = 71/122 (58%), Gaps = 2/122 (1%)
Frame = -3
Query: 646 KLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ- 470
KL +S+A G+TI T+E L + R MPNTPAL+ GA T+E +L +Q
Sbjct: 87 KLLLSIAAGVTIGTLEQ-LFGPVAIARTMPNTPALLSLGATGLYVNDH-TSEVQRLEAQK 144
Query: 469 LFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
+ ++ G C V E +D++TA+SGSGPAY +++IE + G GL R+ A L QT
Sbjct: 145 IIESFGICVAVAKEDLLDSVTAVSGSGPAYYFLMIEEMIKAGTAQGLSREDAAALTVQTA 204
Query: 292 LG 287
LG
Sbjct: 205 LG 206
>UniRef50_Q0P9H8 Cluster: Pyrroline-5-carboxylate reductase; n=10;
Campylobacter|Rep: Pyrroline-5-carboxylate reductase -
Campylobacter jejuni
Length = 243
Score = 83.4 bits (197), Expect = 5e-15
Identities = 52/182 (28%), Positives = 98/182 (53%), Gaps = 1/182 (0%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
AL+ I + + ++ ISV + +++ +R++PNT A K +
Sbjct: 65 ALENIAQMLKGQARILISVLANVDFEKLQTI--KAQNYVRIIPNTAAKYKASTTPYI--L 120
Query: 505 KATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
K + + ++ + K G+ ++ E QM+A A+SG PA++ ++ ES+A+ GV GL
Sbjct: 121 KNSHFENEILD-ILKTFGSAYKLDNEIQMNAAMAISGCAPAFLALIAESIANAGVYEGLS 179
Query: 328 RDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
++L+L L S A+++ +HPA++K+N+ SP G T +G LE+ G R + A++
Sbjct: 180 KELSLNLTRSLFKSSNALLE-HEHPAIIKENICSPGGVTIKGIKILEQKGIRGSFFEAIN 238
Query: 148 AA 143
A+
Sbjct: 239 AS 240
>UniRef50_A7JJ83 Cluster: Pyrroline-5-carboxylate reductase; n=11;
Francisella tularensis|Rep: Pyrroline-5-carboxylate
reductase - Francisella tularensis subsp. novicida
GA99-3549
Length = 274
Score = 83.4 bits (197), Expect = 5e-15
Identities = 54/186 (29%), Positives = 89/186 (47%), Gaps = 4/186 (2%)
Frame = -3
Query: 673 IKNLPSA--KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
IKN+ ++ ++VA GI + E E R +PNTP+ + GA
Sbjct: 77 IKNIRDTVTSTQVIVTVAAGIQTSAYEKLFNKEISFARTIPNTPSSLGYGATGIFFNKVI 136
Query: 499 TAEDAQLTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
A+ L + + +G V E ++D I A++ SGPAY + +E + + V+ GL +
Sbjct: 137 AADKKDLVIDIMQTMGVVTVVEDEKEIDIIAAIASSGPAYYFQFMEHMVEAVVKQGLDKK 196
Query: 322 LALRLAAQTTLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSA 146
A +L QT LG+A M + T ++ + L+ NVTS G T E E+ + A+ A
Sbjct: 197 QAEKLVVQTCLGAAQMALNTNENMSELRKNVTSKKGITYEALNIFEQFNLGGIVDKAIQA 256
Query: 145 AVDRCK 128
+ R +
Sbjct: 257 NIARAQ 262
>UniRef50_Q1NBI0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Sphingomonas sp. SKA58|Rep: Pyrroline-5-carboxylate
reductase - Sphingomonas sp. SKA58
Length = 270
Score = 82.6 bits (195), Expect = 9e-15
Identities = 44/147 (29%), Positives = 72/147 (48%), Gaps = 2/147 (1%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
+S+ G T+ + + P+ ++R MPN P + +G A + L
Sbjct: 92 LSILAGTTLGDLRARFPATGDIVRAMPNLPVGMGQGVVALYTDAHTSPSGRANMEALLGP 151
Query: 457 VGTCDEVPEYQM-DAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSA 281
+G + + + + + +TALSG GPA+++ +++L+ G G+P D A R+A T G+A
Sbjct: 152 LGLSEWMADEALFNRVTALSGCGPAFLFRFVDALSRAGEAIGIPADQAARMAMATVQGAA 211
Query: 280 AMVKTGD-HPAMLKDNVTSPAGSTAEG 203
M PA L D V SP G T EG
Sbjct: 212 NMAAAAQVTPATLADQVASPGGMTREG 238
>UniRef50_Q4WFG1 Cluster: Pyrroline-5-carboxylate reductase; n=3;
Trichocomaceae|Rep: Pyrroline-5-carboxylate reductase -
Aspergillus fumigatus (Sartorya fumigata)
Length = 280
Score = 82.6 bits (195), Expect = 9e-15
Identities = 46/152 (30%), Positives = 78/152 (51%)
Frame = -3
Query: 607 TVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEY 428
T + S+A ++R MPN A +++ + + A + +F+ +G +
Sbjct: 118 TPADDAESKAIIVRAMPNVAARLRQSMTIIEINNNLSHDIADTLTWIFEQIGKVKFLAAD 177
Query: 427 QMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAM 248
D T L GS A + + + + DG V GL R AL +AAQ +G A +++ G HPA+
Sbjct: 178 LFDIGTMLVGSSIAVLTVPFDGILDGCVAEGLRRADALEMAAQNLIGMAGLLREGVHPAI 237
Query: 247 LKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
L+++++SP G T +G +EK G R A A+
Sbjct: 238 LRESISSPRGCTIQGLLAVEKEGMRGACAQAM 269
>UniRef50_A7C3U2 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=1; Beggiatoa sp. PS|Rep: Delta
1-pyrroline-5-carboxylate reductase - Beggiatoa sp. PS
Length = 192
Score = 81.8 bits (193), Expect = 2e-14
Identities = 47/109 (43%), Positives = 65/109 (59%), Gaps = 2/109 (1%)
Frame = -3
Query: 679 KEIKNLPSAKNKLFISVAMGITIATVESNLPSE-ARVIRVMPNTPALVKEGAAAFSRGTK 503
K I LFIS+A GI IA + L ++ ++RVMPNTPALV+ GA+A G
Sbjct: 78 KSIATAMPTSPPLFISIAAGIRIADLAHWLGTQPVPIVRVMPNTPALVRSGASALYAGQH 137
Query: 502 ATAEDAQLTSQLFKAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESL 359
+ +L + ++VG T E QMDA+TALSGSGPAY ++++E L
Sbjct: 138 VSDFQHELAENILRSVGLTVWLSDEKQMDAVTALSGSGPAYFFLIMEML 186
>UniRef50_A0RR69 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Campylobacter fetus subsp. fetus 82-40|Rep:
Pyrroline-5-carboxylate reductase - Campylobacter fetus
subsp. fetus (strain 82-40)
Length = 248
Score = 81.8 bits (193), Expect = 2e-14
Identities = 56/185 (30%), Positives = 98/185 (52%), Gaps = 1/185 (0%)
Frame = -3
Query: 685 ALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGT 506
AL + NL S + ++ ISV I + S++ ++ + +PN A F
Sbjct: 68 ALSSVSNLLSGEAEVCISVLARTGIEMLNSSIKAKNYAV-CLPNIAAKFNSSVTPFI--- 123
Query: 505 KATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLP 329
+ +D + ++ G C ++ + ++DA + L+G PAY+ ++ E+L++ GV GL
Sbjct: 124 -SDGDDNTIV-EILNGFGKCVKLETKNELDAASVLAGCAPAYLALVAEALSNAGVLEGLK 181
Query: 328 RDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
+D A L G A ++K+ HPA++K++V SPAG+T EG LE+ G R A + AV
Sbjct: 182 KDDANFLVNGLFDGFAKLLKSS-HPALIKESVCSPAGTTIEGVAKLEECGVRHAFLQAVK 240
Query: 148 AAVDR 134
A+ +
Sbjct: 241 ASAKK 245
>UniRef50_A3VSN0 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Parvularcula bermudensis HTCC2503|Rep:
Pyrroline-5-carboxylate reductase - Parvularcula
bermudensis HTCC2503
Length = 273
Score = 81.4 bits (192), Expect = 2e-14
Identities = 58/178 (32%), Positives = 85/178 (47%), Gaps = 6/178 (3%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEA---RVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
LFIS+A G ++ + L +A R++R MPN PA + EG + G T +D +
Sbjct: 92 LFISMAAGTSLGEIGKLLKGQAPNARLVRTMPNLPAAIGEGMSLLCAGEGVTDKDKAAAT 151
Query: 472 QLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
L +A G E +D +T +SGSGP +V ++E+ G A LA QT
Sbjct: 152 ALMEAAGQVVWTKTEDDVDRLTGVSGSGPGFVLYVVEAFEAAAKAQGASDSDARLLAEQT 211
Query: 295 TLGSAA-MVKTGDHPAMLKDNVTSPAGSTAEG-TYHLEKNGFRSAIIGAVSAAVDRCK 128
+G+A + + G A L+ VTSP G+T G + I AV AA DR +
Sbjct: 212 IIGTALHLSRDGRTAAELRKAVTSPGGTTEAGLNVLMADERLHRLIAEAVEAAYDRAQ 269
>UniRef50_Q54IL7 Cluster: Pyrroline-5-carboxylate reductase; n=3;
cellular organisms|Rep: Pyrroline-5-carboxylate
reductase - Dictyostelium discoideum AX4
Length = 551
Score = 81.4 bits (192), Expect = 2e-14
Identities = 53/185 (28%), Positives = 90/185 (48%), Gaps = 12/185 (6%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEG------AAAFSRGTKATAE 491
+N + ISV G +I + S+L + ++R MPNT + ++ + T + ++
Sbjct: 91 ENHIIISVVSGASIEDIRSHLEKDVPIVRAMPNTAIQHCQSMTCLAIRSSHQKSTNSPSD 150
Query: 490 DA-----QLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPR 326
A ++ ++F +G + E Q+ TAL G A+ I + A GG G
Sbjct: 151 KAKDNALEVAKKIFNCLGMSIVLSEEQIVPATALCACGIAFFCRAIRAAAQGGCEIGFHA 210
Query: 325 DLALRLAAQTTLGSAA-MVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVS 149
+ A+R+AAQT G+A +++ HP D VT+P G T G +E GF SA+I +
Sbjct: 211 EDAIRIAAQTAKGAATLLLENNFHPEYEIDKVTTPQGCTIAGLNQMEHAGFSSAMIKGIV 270
Query: 148 AAVDR 134
+ D+
Sbjct: 271 TSSDK 275
>UniRef50_UPI000050FC3D Cluster: COG0345: Pyrroline-5-carboxylate
reductase; n=1; Brevibacterium linens BL2|Rep: COG0345:
Pyrroline-5-carboxylate reductase - Brevibacterium
linens BL2
Length = 278
Score = 81.0 bits (191), Expect = 3e-14
Identities = 46/179 (25%), Positives = 85/179 (47%)
Frame = -3
Query: 649 NKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ 470
+ + +S+A G+ +A + + P ++R+MPNTP+ + G A + +
Sbjct: 94 DSVLVSMAAGVAMADLATLAPQNP-IVRIMPNTPSSIGHGVIALAPSAEVDDTIVDTLRT 152
Query: 469 LFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
L G + E ++ A+T +SGSG AY ++L E++ GV+ GL + A ++ T
Sbjct: 153 LLSGAGLVVALDESEIPAMTGISGSGVAYFFLLAETMIAAGVKMGLSEETAKQMVVATAD 212
Query: 289 GSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQ 113
G+ ++ P+ + V+S G+T G G AV AA +R ++K+
Sbjct: 213 GAGRLLTEKPDPSAQRQAVSSKGGTTLAGLQTFIDAGLFDTTEAAVQAAGNRSLEMEKE 271
>UniRef50_A6LE67 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteroidales|Rep: Pyrroline-5-carboxylate reductase -
Parabacteroides distasonis (strain ATCC 8503 / DSM 20701
/ NCTC11152)
Length = 267
Score = 80.6 bits (190), Expect = 4e-14
Identities = 54/189 (28%), Positives = 89/189 (47%), Gaps = 9/189 (4%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEA--------RVIRVMPNTPALVKEGA 527
+ EIK++ + ++ +SVA G+T + + L + R+MPNT A+ +
Sbjct: 79 IDEIKSVLDFEKQIIVSVAAGVTFDLLNTYLTKNTDFDCLATPTIFRIMPNT-AIEVMSS 137
Query: 526 AAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGG 347
F A+ E L +F +G V E M A TAL+ SG A+ I + +GG
Sbjct: 138 MTFVSARNASKEQTDLIIHIFNELGNAMLVEERLMGAGTALASSGIAFALRYIRAAIEGG 197
Query: 346 VRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRS 170
V G A + T G+ +++ +P M D VT+P G T +G +E +GF S
Sbjct: 198 VELGFYPKQAQEIVVHTVKGAVDLLLENKSNPEMEIDKVTTPGGITIKGLNEMELSGFTS 257
Query: 169 AIIGAVSAA 143
++I + A+
Sbjct: 258 SVIRGLKAS 266
>UniRef50_Q6F272 Cluster: 1-pyrroline-5-carboxylate reductase; n=1;
Mesoplasma florum|Rep: 1-pyrroline-5-carboxylate
reductase - Mesoplasma florum (Acholeplasma florum)
Length = 266
Score = 79.8 bits (188), Expect = 6e-14
Identities = 50/188 (26%), Positives = 90/188 (47%), Gaps = 3/188 (1%)
Frame = -3
Query: 688 PALKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARV--IRVMPNTPALVKEGAAAFS 515
P K + L + K I +A +TI V++N +V IR+MPN A +++ A +
Sbjct: 78 PLCKNMDQL-NIDGKTIICMANAVTIEDVQNNFVKNKKVSVIRMMPNMNASIQKSVTALA 136
Query: 514 RGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCG 335
A+ E + S++F+ G + + E + +TA+SG P+Y+ +++ D + G
Sbjct: 137 T-KNASNETMKFVSEMFELCGIVENIDEDKFGTLTAISGCSPSYIISFFKAMTDYAIDKG 195
Query: 334 LPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIG 158
++ A R+ + +GS K+ + D + P GST EG L+ F I
Sbjct: 196 FEKEQAFRIIEEAIIGSVMNASKSEVELRTMVDQICVPNGSTIEGQKILDNKNFEKIIQE 255
Query: 157 AVSAAVDR 134
A++AA +
Sbjct: 256 ALTAATKK 263
>UniRef50_Q1M3U8 Cluster: Putative pyrroline-5-carboxylate
reductase; n=2; Rhizobium|Rep: Putative
pyrroline-5-carboxylate reductase - Rhizobium
leguminosarum bv. viciae (strain 3841)
Length = 264
Score = 78.6 bits (185), Expect = 1e-13
Identities = 54/173 (31%), Positives = 84/173 (48%), Gaps = 2/173 (1%)
Frame = -3
Query: 655 AKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLT 476
A KL ISV GI + + S + RVIR +PN A V + + T +D L
Sbjct: 82 AGGKLIISVMAGIRLDAL-SERHNTGRVIRALPNAAAEVAKSYTPWIGARDVTEDDRALV 140
Query: 475 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQ 299
+F+A G+ DEV E +D +T LSGSGPA+ +L ++ V GLP ++A R
Sbjct: 141 RAIFQACGSEDEVARESDIDYLTGLSGSGPAFPALLAAAMMRDAVANGLPAEIARRAVNT 200
Query: 298 TTLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
G+ +++ D P + + G+TA + GF +++ +SAA
Sbjct: 201 VITGAGRLLERHDECPDDVVETFVGYRGTTAAAIEGMRVAGFDASVAKGLSAA 253
>UniRef50_A0HA22 Cluster: NADP oxidoreductase, coenzyme
F420-dependent; n=1; Comamonas testosteroni KF-1|Rep:
NADP oxidoreductase, coenzyme F420-dependent - Comamonas
testosteroni KF-1
Length = 268
Score = 77.4 bits (182), Expect = 3e-13
Identities = 50/189 (26%), Positives = 91/189 (48%), Gaps = 7/189 (3%)
Frame = -3
Query: 658 SAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAED--A 485
S K + +S+ GI++ T+++ P +R+IR++PNTP G + + A
Sbjct: 80 SHKVDIVVSMMAGISVDTIKTVFPG-SRIIRIIPNTPCAFGAGITPIYTDFNSLKDTTTA 138
Query: 484 QLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 305
+ + L + + E ++ T +S GPAY+ ++ E++ G + +L
Sbjct: 139 SVLTALSRLGPLMPVLDEPMINCATGISAGGPAYIMLIAEAMISTAEEMGFEPAESRQLV 198
Query: 304 AQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEK----NGFRSAIIGAVSAAV 140
A T LGSA +++T P L V +P G+T G L++ N FR+A++ A A+
Sbjct: 199 AHTLLGSAELLIQTSKSPRELAQEVMTPNGTTERGVSELQRRDIGNSFRTALLNASKRAI 258
Query: 139 DRCKIVKKQ 113
D + + Q
Sbjct: 259 DIARESRNQ 267
>UniRef50_A3M414 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Acinetobacter baumannii ATCC 17978|Rep:
Pyrroline-5-carboxylate reductase - Acinetobacter
baumannii (strain ATCC 17978 / NCDC KC 755)
Length = 182
Score = 76.6 bits (180), Expect = 6e-13
Identities = 55/174 (31%), Positives = 78/174 (44%), Gaps = 2/174 (1%)
Frame = -3
Query: 622 GITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVG-TC 446
G+ I + S + ++IRV+ N P L G D ++ ++ A G T
Sbjct: 4 GVNIQQLMS-ITGSKKIIRVISNPPVLTYTGTHVLIGSDYLEPLDKEVIETIYSATGRTY 62
Query: 445 DEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-K 269
E Q DAI ALSGSGPAY + +++S+ GV GL + AL L Q G+ MV K
Sbjct: 63 WANSESQSDAIIALSGSGPAYFFYILDSMVKTGVSMGLDKQFALDLILQAASGAVEMVRK 122
Query: 268 TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKKQLN 107
+ P+ L VT G T E I A+ AA R K + ++N
Sbjct: 123 SNVQPSELCGKVTLANGITESALRMFELGNLSDDIRLALKAAYHRSKEISLEIN 176
>UniRef50_Q0AL89 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Alphaproteobacteria|Rep: Pyrroline-5-carboxylate
reductase - Maricaulis maris (strain MCS10)
Length = 259
Score = 76.2 bits (179), Expect = 8e-13
Identities = 50/172 (29%), Positives = 83/172 (48%), Gaps = 3/172 (1%)
Frame = -3
Query: 640 FISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFK 461
++S+A G + A++ L + VIR+MPN PAL+ + L ++L +
Sbjct: 84 YVSIAAGFSTASL-GKLVGDQPVIRIMPNLPALIGRSVNGLFANPTCQDKHRDLANELAR 142
Query: 460 AVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
GT + E ++D +TA++GSGP YV+ + S G ++ A L +T G+
Sbjct: 143 TTGTAVWLDDEDELDRLTAIAGSGPGYVFEIARSYVAAAQALGFSKETARALVLETMGGA 202
Query: 283 AAMVKTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNGFRSAII-GAVSAAVDR 134
M D A L+++V S G+T G L ++G A++ AA DR
Sbjct: 203 IEMATRSDQDVADLRNSVMSKNGTTEAGINVLRRDGQLDALLRDTTRAAYDR 254
>UniRef50_A1B1A3 Cluster: NADP oxidoreductase, coenzyme
F420-dependent; n=1; Paracoccus denitrificans
PD1222|Rep: NADP oxidoreductase, coenzyme F420-dependent
- Paracoccus denitrificans (strain Pd 1222)
Length = 262
Score = 76.2 bits (179), Expect = 8e-13
Identities = 50/157 (31%), Positives = 78/157 (49%), Gaps = 3/157 (1%)
Frame = -3
Query: 577 RVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVP-EYQMDAITALS 401
R++RVMPN A + + F T D +L A+GT DE+ E Q+D +TAL
Sbjct: 104 RIVRVMPNAAAEIGGSYSPFWVAEGVTDADRDTVRRLLSAIGTTDELETEAQIDLMTALP 163
Query: 400 GSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV--KTGDHPAMLKDNVTS 227
GSG AY ++ ++A G+ +A R A +G A ++ + + PAM+
Sbjct: 164 GSGAAYPALMAVAMAGFMQAQGVSEPIAWRAAEAAVIGGARLLEGRISEAPAMVA-AYRD 222
Query: 226 PAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVKK 116
G+TA G E GF A++ A+ AA D+ + + K
Sbjct: 223 YRGTTAAGLEAAEAAGFSRAVVAALEAATDKARRMAK 259
>UniRef50_Q7YYR6 Cluster: Pyrroline-5-carboxylate reductase,
possible; n=3; Cryptosporidium|Rep:
Pyrroline-5-carboxylate reductase, possible -
Cryptosporidium parvum
Length = 284
Score = 76.2 bits (179), Expect = 8e-13
Identities = 54/201 (26%), Positives = 92/201 (45%), Gaps = 12/201 (5%)
Frame = -3
Query: 682 LKEIKNLP-----SAKNKLFISVAMGITIATVESNLPS-EARVIRVMPNTPALVKEGAAA 521
L EI NL + +K+ ISV G TI+ + S E IRVMPN + +G
Sbjct: 83 LSEINNLNIESDLKSGDKVLISVCAGKTISDILKEFQSNEIHCIRVMPNLTLSICQGTWL 142
Query: 520 FSRG-----TKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLA 356
+ TK ++ ++ + GT ++ E T++SG GP Y +
Sbjct: 143 YYENPVAHFTKYKQNNSNEIIEILSSCGTVYKINEDIFSHCTSISGCGPGYFSNIAHHFI 202
Query: 355 DGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVTSPAGSTAEGTYHLEKNG 179
G++ G+P DLA +L +T G++ ++ ++ P + + V++P GST G LE
Sbjct: 203 QSGIKIGIPEDLARKLVIETMYGTSKLLFESSIDPQVFQSKVSTPGGSTQAGIDILEDRL 262
Query: 178 FRSAIIGAVSAAVDRCKIVKK 116
+ +++DRC + K
Sbjct: 263 IGKIFQDCLYSSLDRCNQLSK 283
>UniRef50_A7AD19 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 268
Score = 75.8 bits (178), Expect = 1e-12
Identities = 53/190 (27%), Positives = 86/190 (45%), Gaps = 10/190 (5%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEA---------RVIRVMPNTPALVKEG 530
+ +IK + ++ +SVA GIT + + L + R+MPNT A+
Sbjct: 79 IDQIKGILDYDKQIIVSVAAGITFDLLNTYLTKNTGFDDCLTTPTIFRIMPNT-AIEVLS 137
Query: 529 AAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADG 350
+ F A+ E L +F +G V E M A TAL+ SG A+ I + +G
Sbjct: 138 SMTFVAARNASKEQTDLIINIFNELGNAMLVEERLMSAGTALASSGIAFALRYIRAAIEG 197
Query: 349 GVRCGLPRDLALRLAAQTTLGSA-AMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFR 173
GV G A + T G+ +++ +P D VT+P G T +G +E +GF
Sbjct: 198 GVELGFYPKQAQEIVVHTVKGAVDLLLENKSNPETEIDKVTTPGGITIKGLNEMELSGFT 257
Query: 172 SAIIGAVSAA 143
S++I + A+
Sbjct: 258 SSVIRGLKAS 267
>UniRef50_A6DA85 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=1; Caminibacter mediatlanticus TB-2|Rep: Delta
1-pyrroline-5-carboxylate reductase - Caminibacter
mediatlanticus TB-2
Length = 247
Score = 75.8 bits (178), Expect = 1e-12
Identities = 53/189 (28%), Positives = 93/189 (49%), Gaps = 4/189 (2%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L+E+ + K+ IS+ G ++ +E + S +R MPN AA + T
Sbjct: 68 LQEVSMRIKGEAKVLISILAGKSVFEIEKYIKSNY-YLRAMPNI-------AAKYQASTT 119
Query: 502 ATAEDAQLTSQLFKAVGTCDEV----PEYQMDAITALSGSGPAYVYMLIESLADGGVRCG 335
A D ++ K +G +V + ++D TA+ GSGPA++ ++ ++ D GV G
Sbjct: 120 ALTGDVEVKELGEKILGYIGDVIWVNNDDEIDMATAIIGSGPAFLSLIASAIEDAGVYTG 179
Query: 334 LPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGA 155
L R+++ +L ++ + D +K+ V SP G+TAEG Y LE++G R I+
Sbjct: 180 LKREISHKLTKGLFKSFTSLKENFD---TIKNQVMSPKGTTAEGVYSLEEDGIRGKIMKG 236
Query: 154 VSAAVDRCK 128
V ++ K
Sbjct: 237 VIKTYEKSK 245
>UniRef50_Q7VHX1 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Helicobacter hepaticus|Rep: Pyrroline-5-carboxylate
reductase - Helicobacter hepaticus
Length = 284
Score = 74.5 bits (175), Expect = 2e-12
Identities = 54/174 (31%), Positives = 87/174 (50%), Gaps = 5/174 (2%)
Frame = -3
Query: 634 SVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQ----L 467
SV G +IA ++ +L S + ++R+MPN A K A AF T + AQ+
Sbjct: 98 SVLAGTSIAMIQKHL-SASSIVRLMPNIAAHSKLSATAFYYHMLDTKDSAQVLHNEIRPF 156
Query: 466 FKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTL 290
++ G +V E +++ A SGS A++ ++ ESL D G+ GL ++ L QT +
Sbjct: 157 IESFGVAVQVDSEALIESSIAASGSSIAFLALIAESLIDAGILEGLNEQQSIALVKQTFV 216
Query: 289 GSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
G A + P LK ++SP G+T G LE++G R +I A A + +
Sbjct: 217 GFATEL-AHKSPNELKYAISSPGGTTIRGLAVLEESGMRGILIKAAHTAAEHAR 269
>UniRef50_Q5FK14 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteria|Rep: Pyrroline-5-carboxylate reductase -
Lactobacillus acidophilus
Length = 91
Score = 73.7 bits (173), Expect = 4e-12
Identities = 40/83 (48%), Positives = 53/83 (63%), Gaps = 1/83 (1%)
Frame = -3
Query: 406 LSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMV-KTGDHPAMLKDNVT 230
+SG GPA+V + +++L D GV GL RD A LAA GSA + +T PA+L+D V
Sbjct: 4 ISGYGPAFVDIFLDALGDAGVLNGLSRDQANTLAANMVKGSANLAYETKIAPAILRDQVC 63
Query: 229 SPAGSTAEGTYHLEKNGFRSAII 161
SP G+T +G LEK+GFR II
Sbjct: 64 SPGGTTIQGVASLEKHGFRYTII 86
>UniRef50_A3Y9M8 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Marinomonas sp. MED121|Rep: Pyrroline-5-carboxylate
reductase - Marinomonas sp. MED121
Length = 261
Score = 70.9 bits (166), Expect = 3e-11
Identities = 47/172 (27%), Positives = 80/172 (46%), Gaps = 5/172 (2%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L +S+ G++ A ++ P ++V+R MPNTP G ++ + S
Sbjct: 77 LIVSMLAGVSCAEIQHYFP-HSQVVRCMPNTPCEFGVGITPIYFSGNSSGTFSAHYSAFL 135
Query: 463 KAVGTCDEV----PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
+A E+ E +D T +SG GPAYV ++ +++ G + + RL +T
Sbjct: 136 EAAQFMGELFFVEKESDIDGATGISGGGPAYVMLMADAMIKASQTLGFSYEESKRLVGKT 195
Query: 295 TLGSAAMVKTGDH-PAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAA 143
GS M++ D PA L +V +P G+T +G L+ +AI A+ A
Sbjct: 196 LEGSGKMLQMSDKMPAQLAQDVMTPNGTTEQGVNELKAKQVETAIYDALLKA 247
>UniRef50_A3K0L9 Cluster: Putative pyrroline-5-carboxylate reductase
protein; n=1; Sagittula stellata E-37|Rep: Putative
pyrroline-5-carboxylate reductase protein - Sagittula
stellata E-37
Length = 255
Score = 70.9 bits (166), Expect = 3e-11
Identities = 54/180 (30%), Positives = 85/180 (47%), Gaps = 3/180 (1%)
Frame = -3
Query: 658 SAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAE-DAQ 482
+A + L +SV G T A ++ S RVIR M ++PA + A G+ A E D
Sbjct: 75 AAPDALVLSVIAGATRARLQETTGSP-RVIRAM-SSPAAARRLAYTPWIGSAAITEADRT 132
Query: 481 LTSQLFKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 305
+ +F A+G DE+ E +D TAL+G P + + ++A V G+P D+A R
Sbjct: 133 QANAVFSAIGRTDEIGDEAHIDLFTALTGPVPGFAALFASAMARHAVSQGVPPDIADRAV 192
Query: 304 AQTTLGSAAMVKTGDHPAMLK-DNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
Q L + M+ H A + + + AG+TA G + G + + AA DR +
Sbjct: 193 RQLFLSAGEMLAHDAHTADAHVEGMIAYAGTTAAGFLSMRAAGLEEIVANGLQAATDRAR 252
>UniRef50_A5EV67 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Dichelobacter nodosus VCS1703A|Rep:
Pyrroline-5-carboxylate reductase - Dichelobacter
nodosus (strain VCS1703A)
Length = 285
Score = 70.5 bits (165), Expect = 4e-11
Identities = 40/124 (32%), Positives = 61/124 (49%), Gaps = 1/124 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
+ I++A GI I L E ++R MPN A V+ + D L +F
Sbjct: 95 VIITLAAGIKIEDYRKILGDEVTIVRAMPNIAASVQAALTGIYSDDGLSEHDENLIEDIF 154
Query: 463 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
A+G+ + E Q+D ITALSGSG AY Y L++++A G + G + + T LG
Sbjct: 155 SAIGSTAWLDDEIQLDGITALSGSGIAYFYRLMQAMAQAGEQYGFEKQELYDIITLTALG 214
Query: 286 SAAM 275
+A +
Sbjct: 215 AATL 218
>UniRef50_Q41BC1 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Exiguobacterium sibiricum 255-15|Rep:
Pyrroline-5-carboxylate reductase - Exiguobacterium
sibiricum 255-15
Length = 256
Score = 69.3 bits (162), Expect = 9e-11
Identities = 51/179 (28%), Positives = 81/179 (45%), Gaps = 2/179 (1%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
L IK ++L +SVA IT A +E+++ A + MPNTP + G G
Sbjct: 73 LDYIKQQTWRTDQLVVSVAAHITPAEIEAHISCGA--VCAMPNTPVAFRTGMTGLWFGDL 130
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRD 323
+ E Q + LF VG E M + A +G PA+ Y ++ ++ + G
Sbjct: 131 VSDEKRQQATALFGRVGETVETNAATMPYLMAAAGCSPAFFYEIVGAMTPVLTKAGFDAS 190
Query: 322 LALRLAAQTTLGSAAMVKTGDHPA--MLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAV 152
A R+ AQ GSA ++ + P ++KD V +P G T G L ++ A+ A+
Sbjct: 191 SARRIIAQAMKGSAELLLHEERPTEELIKD-VAAPGGPTDRGVRVLREHDLAQAMYEAL 248
>UniRef50_Q0G398 Cluster: Putative pyrroline-5-carboxylate reductase
protein; n=1; Fulvimarina pelagi HTCC2506|Rep: Putative
pyrroline-5-carboxylate reductase protein - Fulvimarina
pelagi HTCC2506
Length = 266
Score = 68.5 bits (160), Expect = 2e-10
Identities = 46/177 (25%), Positives = 80/177 (45%), Gaps = 2/177 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
+ +S G+ +A +E N P +AR++R MP A D L +L
Sbjct: 87 IVVSFMAGVPLAHLERNWP-DARIVRAMPGGGAREGNAHVPICAADGIADADLDLVERLL 145
Query: 463 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
+GT D V E+++ +TALSGSG AY ++ +++ D GV G+ ++ R
Sbjct: 146 SVIGTVDRVANEHELAFLTALSGSGAAYPALMAKAMYDRGVAEGITPEVVWRAVTSVVCD 205
Query: 286 SAAMVKTGDHPAM-LKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 119
+ ++++ A + + + G TA G G AI A+ AA R + ++
Sbjct: 206 APSLLRGSPAEASHMLETLEGYRGPTAAGIEAARLAGLGKAIGSALDAATKRAETMR 262
>UniRef50_A2A043 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Bacteroidetes|Rep: Pyrroline-5-carboxylate reductase -
Microscilla marina ATCC 23134
Length = 266
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/121 (30%), Positives = 65/121 (53%), Gaps = 1/121 (0%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L IS+ GI+I ++ +P+ ++IR MPN PA + G F+ ++ + L
Sbjct: 90 LLISIMAGISIDKIKRWVPT-TKIIRAMPNLPAQIGMGMTGFTAAASVDKKELFIVQNLI 148
Query: 463 KAVG-TCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
G + E +++A+TA+SGSGPAYV+ ++++ D + G + A L QT +G
Sbjct: 149 NTTGKSLYFEDEEKLNAVTAISGSGPAYVFYFMQAMMDTAQQMGFSQSEAELLVEQTFMG 208
Query: 286 S 284
+
Sbjct: 209 A 209
>UniRef50_A3SP40 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Roseovarius nubinhibens ISM|Rep: Pyrroline-5-carboxylate
reductase - Roseovarius nubinhibens ISM
Length = 264
Score = 67.7 bits (158), Expect = 3e-10
Identities = 46/174 (26%), Positives = 80/174 (45%), Gaps = 2/174 (1%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L +SV G+++A + + A V+R MPN + + + + +A D + +
Sbjct: 89 LVLSVMAGVSMAEIRERTGARA-VVRSMPNAAMEIGQSFSPWVAEAEADDADRAMVRAVL 147
Query: 463 KAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLG 287
A G + E +D A+ G+GPA+ +L+E+LA G GL + AL A +G
Sbjct: 148 GASGREEAFAREADIDVYAAICGAGPAWAALLLEALAAAGRAEGLSPEQALAAAEGAVVG 207
Query: 286 SAAMVK-TGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCK 128
+ AM+ G + D + AG+TA G GF A+ ++A + +
Sbjct: 208 AGAMLAGQGAQAGAMVDEFIAYAGTTAAGLEAARAAGFAEAVAAGIAAGTQKAR 261
>UniRef50_Q83FH8 Cluster: Pyrroline-5-carboxylate reductase; n=2;
Tropheryma whipplei|Rep: Pyrroline-5-carboxylate
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 296
Score = 66.9 bits (156), Expect = 5e-10
Identities = 31/127 (24%), Positives = 61/127 (48%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
+ KL +S+A + ++ + + LPS ++R N P V+ G S D +
Sbjct: 114 RKKLIVSLAKDVNLSNLAAMLPSGTAIVRCATNLPITVRHGFTGLSCNKHVLPSDVKAVY 173
Query: 472 QLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTT 293
LF+ +G C + E + ++A++G P Y+ ++ + + + GLPRD++
Sbjct: 174 TLFELLGRCTMLSEEHLTIVSAITGFYPVYMLYMLTKIKEATEKLGLPRDISQAAVETAW 233
Query: 292 LGSAAMV 272
+G A +V
Sbjct: 234 IGYAQVV 240
>UniRef50_A3UDP5 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=1; Oceanicaulis alexandrii HTCC2633|Rep: Delta
1-pyrroline-5-carboxylate reductase - Oceanicaulis
alexandrii HTCC2633
Length = 251
Score = 66.9 bits (156), Expect = 5e-10
Identities = 54/172 (31%), Positives = 82/172 (47%), Gaps = 4/172 (2%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
+S+A G + A V S +R+MPN PA V G + +AT + +L + L +A
Sbjct: 76 VSIAAGASAAKV-SEAAGGVSALRLMPNMPARVGRGVSGLYADDRATKDHRELGTTLGEA 134
Query: 457 VGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGL-PRDLALRLAAQTTLGS 284
VG + E Q+D ITA +GSGP YV+ + G P+D A RL +T G
Sbjct: 135 VGEAIWLEDEDQIDRITAAAGSGPGYVFEFARTYQKAVEAQGFDPKD-ARRLVIETLAGC 193
Query: 283 AAMVKTGDHP-AMLKDNVTSPAGSTAEGTYHLEKNG-FRSAIIGAVSAAVDR 134
A+ + L++++ S G+TA G L +G + A+ AA R
Sbjct: 194 MALALEDEAGFEDLRNSIMSKGGTTAAGVNALNGDGVLDERLNAALDAAYSR 245
>UniRef50_Q59UW8 Cluster: Putative uncharacterized protein; n=2;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 213
Score = 65.3 bits (152), Expect = 1e-09
Identities = 55/171 (32%), Positives = 75/171 (43%), Gaps = 2/171 (1%)
Frame = +3
Query: 144 AADTAPI-MAERKPFFSK*YVPSAVDPAGLVTLSFNMAG*SPVL-TMAAEPRVVWXXXXX 317
AA + P+ +A P S P V P G+ TL FN AG SPV T+ A P +
Sbjct: 37 AASSTPLAIALLNPRSSMVNKPPIVVPPGVHTLLFNAAGCSPVSKTIRAVPSITLAAATD 96
Query: 318 XXXXGKPQRTPPSARDSISM*T*AGPLPLRAVIASIWYSGTSSQVPTALKSCDXXXXXXX 497
G P T PS DSI AGP P+ V S+++SG + +PT +
Sbjct: 97 ATSYGIPILTAPSIMDSIINKQKAGPDPINEVAMSMFFSGIFTVIPTVSINFITNSWLSS 156
Query: 498 XXXXPRLKAAAPSFTNAGVFGITRITRASEGKFDSTVAIVIPMATEMKSLF 650
AA P +AGV +T T K D++ IV+P E+ + F
Sbjct: 157 LTSGANAIAAVPQPNSAGVLVMTLATYGV--KIDNSF-IVVPANNEINNCF 204
>UniRef50_Q67T73 Cluster: ComE operon protein 4; n=1;
Symbiobacterium thermophilum|Rep: ComE operon protein 4
- Symbiobacterium thermophilum
Length = 270
Score = 64.1 bits (149), Expect = 3e-09
Identities = 48/181 (26%), Positives = 87/181 (48%), Gaps = 7/181 (3%)
Frame = -3
Query: 643 LFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLF 464
L +++ +T+A +E+ P AR +V+P+ V+ G + G + T D L +L
Sbjct: 91 LLVTINNTVTLAMLEARTP--ARAAKVIPSVVHAVRRGVSLLVFGGRCTHRDRALLMRLM 148
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADG--GVRCGLPRDLALRLAAQTTL 290
AV VPE + + L+ GPA++ +++ ++A+ G L R+ + + +T
Sbjct: 149 GAVSRPFVVPEEAVRTASDLTACGPAFLSLVLHAMAEAARGKAPALSREAVMAMVRETAR 208
Query: 289 GSA-AMVKTGDHPAMLKDNVTSPAGSTAEG--TYHLEKNGFRSAIIGAVSA--AVDRCKI 125
+ M +TG A + V +P G A G H +GF A++ A +A A R ++
Sbjct: 209 ATCELMEQTGYDFADVAARVATPGGVAAAGVDALHPRLDGFWEAVLAATAAHEAAKRAQL 268
Query: 124 V 122
V
Sbjct: 269 V 269
>UniRef50_Q5FGR8 Cluster: Pyrroline-5-carboxylate reductase; n=6;
canis group|Rep: Pyrroline-5-carboxylate reductase -
Ehrlichia ruminantium (strain Gardel)
Length = 303
Score = 63.3 bits (147), Expect = 6e-09
Identities = 43/149 (28%), Positives = 79/149 (53%), Gaps = 2/149 (1%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
K+ FIS+ GI I ++ +L S +IRVMPN + E + + + ++ Q
Sbjct: 118 KSASFISLCAGIDIEFLKKHLDSTT-IIRVMPNIAMSLGE-SVNLAYMEEEIDQEKQKVH 175
Query: 472 QLFKAVGTCDEVPEYQM-DAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
+F G + + + D ++ ++GSGPAY + L E L ++ G+ + A++L +QT
Sbjct: 176 TVFNGTGLLYWLQKEDVFDKLSPITGSGPAYFFSLAEELVKNTMKAGIREEDAIKLISQT 235
Query: 295 TLGSAAMVKTGDHP-AMLKDNVTSPAGST 212
+GSA +++T + + L ++TS G T
Sbjct: 236 FIGSAKLLETRKNSISNLISSITSRGGIT 264
>UniRef50_O25773 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Helicobacter|Rep: Pyrroline-5-carboxylate reductase -
Helicobacter pylori (Campylobacter pylori)
Length = 257
Score = 61.7 bits (143), Expect = 2e-08
Identities = 37/122 (30%), Positives = 64/122 (52%), Gaps = 1/122 (0%)
Frame = -3
Query: 487 AQLTSQLFKAVGTCDEVPEYQM-DAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 311
+Q + ++ G C V ++ DA A +GS A++ ++ SL D G+R GL +L
Sbjct: 137 SQKALSVIESFGNCVRVGHEELVDASVATNGSALAFLSLVANSLKDAGIREGLNARGSLE 196
Query: 310 LAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRC 131
L + G A +++ + P M+ + + +P G+T EG LEK G R A I A +V +
Sbjct: 197 LVKMSFKGFAKLLEK-ERPEMIIEQICTPKGATIEGLSVLEKKGVRGAFIEACHKSVKKM 255
Query: 130 KI 125
++
Sbjct: 256 RL 257
>UniRef50_Q2FQL0 Cluster: NADP oxidoreductase, coenzyme
F420-dependent; n=1; Methanospirillum hungatei JF-1|Rep:
NADP oxidoreductase, coenzyme F420-dependent -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 227
Score = 56.8 bits (131), Expect = 5e-07
Identities = 35/126 (27%), Positives = 58/126 (46%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKA 458
+S+A I IAT+ + VIR++PN + V EG G+ + ++L A
Sbjct: 63 VSLAPKIKIATINQLTGASRSVIRMIPNAASYVNEGYNPVVFGSSCPENIRKKFTELMVA 122
Query: 457 VGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAA 278
+G EVPE ++A T ++ GP Y++ + L GL + A G+A
Sbjct: 123 LGQMPEVPEEMLEAYTVITAMGPTYLWFQLAELIHLAQTFGLTQKDATDAVLPMAEGAAK 182
Query: 277 MVKTGD 260
++K D
Sbjct: 183 IMKKSD 188
>UniRef50_Q6MQK1 Cluster: ProC protein; n=1; Bdellovibrio
bacteriovorus|Rep: ProC protein - Bdellovibrio
bacteriovorus
Length = 275
Score = 55.6 bits (128), Expect = 1e-06
Identities = 46/183 (25%), Positives = 84/183 (45%), Gaps = 2/183 (1%)
Frame = -3
Query: 652 KNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDAQLTS 473
++K+ ISVA GI + +E + AR+ RVMPNTP+L+ G + +
Sbjct: 93 EHKIVISVAAGIRMEKLERYVQG-ARLARVMPNTPSLIGRGVIGYLLNDDDDSGLDSTVE 151
Query: 472 QLFKAVGTCDEV-PEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQT 296
LF+ +G +V E Q +A+ SG +V+ ++ D G + A + +T
Sbjct: 152 DLFQPLGRVIQVHDEDQFEALMVSCSSGTGFVFEMMMYWQDWIEEHGFSVEEARMMTIET 211
Query: 295 TLGSAAM-VKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAIIGAVSAAVDRCKIVK 119
+G++ + + + L+ VTS G TA G + + A+ + A R K +
Sbjct: 212 FVGASLLAAQAREGVEDLQARVTSKKGVTAAGLQSMRELEIERALRISFEKAAMRNKEMA 271
Query: 118 KQL 110
+++
Sbjct: 272 REI 274
>UniRef50_A4R344 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 241
Score = 54.0 bits (124), Expect = 4e-06
Identities = 38/121 (31%), Positives = 57/121 (47%), Gaps = 2/121 (1%)
Frame = -3
Query: 664 LPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKATAEDA 485
L +A +++ G+++A + S LP V+R MPN P ++GA S A
Sbjct: 108 LRAAARPTVVTMCPGVSVAQLLSWLPRGTPVVRSMPNLPVTRRQGALFPS--ADAVGGSV 165
Query: 484 QLTSQLFKAVGTCDEV-PEYQM-DAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALR 311
+L + + V V PE + D ++SGS PAY Y LIESL G+ + A
Sbjct: 166 ELVAAVLGLVSPAVSVLPEESLLDVAASVSGSAPAYFYYLIESLVSAAEARGMSAETARS 225
Query: 310 L 308
L
Sbjct: 226 L 226
>UniRef50_UPI0000E45EAB Cluster: PREDICTED: similar to
pyrroline-5-carboxylate reductase-like; n=1;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyrroline-5-carboxylate reductase-like -
Strongylocentrotus purpuratus
Length = 120
Score = 53.6 bits (123), Expect = 5e-06
Identities = 43/140 (30%), Positives = 63/140 (45%)
Frame = -3
Query: 562 MPNTPALVKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAY 383
MPN V EG + RG AT ED + +L + + + + Q+D
Sbjct: 1 MPNVAIAVCEGNISGVRGAHATDEDMVVVGKLMNPISNYEVMSDPQLD------------ 48
Query: 382 VYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEG 203
++ S A GV G + ++TG HP +KD+V SP GST G
Sbjct: 49 ---IMSSTAGTGVAWGTGK---------------LYLETGKHPGEIKDSVCSPGGSTIRG 90
Query: 202 TYHLEKNGFRSAIIGAVSAA 143
+ LEK+G R+A++ AV AA
Sbjct: 91 VHALEKSGVRAAMMNAVEAA 110
>UniRef50_Q4ML40 Cluster: Pyrroline-5-carboxylate reductase; n=1;
Bacillus cereus G9241|Rep: Pyrroline-5-carboxylate
reductase - Bacillus cereus G9241
Length = 163
Score = 51.6 bits (118), Expect = 2e-05
Identities = 27/84 (32%), Positives = 46/84 (54%)
Frame = -3
Query: 682 LKEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTK 503
+ EIK + + + +++A G +I + E+ + +V+RVMPNTPALV EG +A
Sbjct: 80 INEIKEVIK-NDAIIVTIAAGKSIESTENAFNKKLKVVRVMPNTPALVGEGMSALCPNEM 138
Query: 502 ATAEDAQLTSQLFKAVGTCDEVPE 431
T +D + +F + G + V E
Sbjct: 139 VTEKDLEDVLNIFNSFGQSEIVSE 162
>UniRef50_A6RTE4 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 362
Score = 50.8 bits (116), Expect = 3e-05
Identities = 26/125 (20%), Positives = 62/125 (49%), Gaps = 2/125 (1%)
Frame = -3
Query: 637 ISVAMGITIATVESNLPSEARVIRVMPNTPALVKEG--AAAFSRGTKATAEDAQLTSQLF 464
++ A+GI+ +++ E ++R MP+ A E S T + ++ + +F
Sbjct: 139 MTAALGISESSIGKGKGKEIAIVRAMPSLAASFGESNTVVEISPSTALSQQNKSIVRYIF 198
Query: 463 KAVGTCDEVPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGS 284
+ +G+ EV Q DA + ++ + A++ + ++ + DGGV+ G+ R + ++ G
Sbjct: 199 RCIGSIVEVGPGQYDAASVMAATSMAFLTVALDGILDGGVKEGIKRSEGRDILVRSLKGL 258
Query: 283 AAMVK 269
+++
Sbjct: 259 VGLLE 263
>UniRef50_A1FCT9 Cluster: Pyrroline-5-carboxylate reductase-like;
n=1; Pseudomonas putida W619|Rep:
Pyrroline-5-carboxylate reductase-like - Pseudomonas
putida W619
Length = 121
Score = 50.4 bits (115), Expect = 5e-05
Identities = 28/58 (48%), Positives = 38/58 (65%), Gaps = 1/58 (1%)
Frame = -3
Query: 475 SQLFKAVGTCDEVP-EYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLA 305
++LF+AVG+ V E +D +TALSGSGPAY + E+L+ GV GL +LA LA
Sbjct: 27 TRLFEAVGSTSWVEHEGLLDTVTALSGSGPAYYQLFSEALSAAGVALGLSPELARTLA 84
>UniRef50_UPI00015BAEC8 Cluster: pyrroline-5-carboxylate reductase;
n=1; Ignicoccus hospitalis KIN4/I|Rep:
pyrroline-5-carboxylate reductase - Ignicoccus
hospitalis KIN4/I
Length = 245
Score = 49.6 bits (113), Expect = 8e-05
Identities = 40/134 (29%), Positives = 61/134 (45%), Gaps = 1/134 (0%)
Frame = -3
Query: 577 RVIRVMPNTPALVKEGAAAFS-RGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALS 401
+V RVMP+ V + RG A + + ++ +G V E +DA +
Sbjct: 99 KVYRVMPSVTVEVNSSPVLVAERGGGADS----VVEAVWGKLGKVYWVNERVLDAALPVV 154
Query: 400 GSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGDHPAMLKDNVTSPA 221
GSGPA S + V G+ R LA LA ++ +G+ M++ D P L+ V +P
Sbjct: 155 GSGPAVHAEYFRSAVEALVASGVERSLAEELARESIIGTIKMLEKYD-PYKLRSKVETPG 213
Query: 220 GSTAEGTYHLEKNG 179
G T E LE+ G
Sbjct: 214 GITVEMLLKLEEEG 227
>UniRef50_Q4FKY2 Cluster: Delta 1-pyrroline-5-carboxylate reductase;
n=2; Candidatus Pelagibacter ubique|Rep: Delta
1-pyrroline-5-carboxylate reductase - Pelagibacter
ubique
Length = 255
Score = 48.8 bits (111), Expect = 1e-04
Identities = 45/175 (25%), Positives = 75/175 (42%), Gaps = 3/175 (1%)
Frame = -3
Query: 679 KEIKNLPSAKNKLFISVAMGITIATVESNLPSEARVIRVMPNTPALVKEGAAAFSRGTKA 500
K IKNL N+ IS IT+A ++ + +A++IR +P P +K+G K
Sbjct: 76 KIIKNLKFRSNQTVISFISTITLAQLKKAIKVKAKIIRAIPLPPISLKKGPVPICPPNKK 135
Query: 499 TAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSG-PAYVYMLIESLADGGVRCGLPRD 323
+ F +GT E+ + + +I S SG A Y L+ + D V+ G+ R+
Sbjct: 136 VKD-------FFNKIGTTVEI-KNEKSSINFWSTSGMMAPFYELLRVMTDWLVKRGVKRN 187
Query: 322 LALRLAAQ--TTLGSAAMVKTGDHPAMLKDNVTSPAGSTAEGTYHLEKNGFRSAI 164
A + L A+V + L +P G +G L + GF ++
Sbjct: 188 NAQKYITSLFLALSEDAVVNSKKDLKFLVKESQTPKGLNEQGVKELSRAGFYKSL 242
>UniRef50_Q8ZW86 Cluster: Pyrroline-5-carboxylate reductase; n=4;
Pyrobaculum|Rep: Pyrroline-5-carboxylate reductase -
Pyrobaculum aerophilum
Length = 238
Score = 39.9 bits (89), Expect = 0.064
Identities = 28/87 (32%), Positives = 39/87 (44%)
Frame = -3
Query: 439 VPEYQMDAITALSGSGPAYVYMLIESLADGGVRCGLPRDLALRLAAQTTLGSAAMVKTGD 260
V E +D +T L GSGPA V L +L GV G+P DL+ R + + S +
Sbjct: 134 VEERLIDPLTVLLGSGPAIVAELALALIRAGVNIGIPWDLS-REIVLSLMASLPSLDDKF 192
Query: 259 HPAMLKDNVTSPAGSTAEGTYHLEKNG 179
L V +P G+T + L G
Sbjct: 193 SMEKLAQYVATPGGTTIKALVELSPAG 219
>UniRef50_Q8TGP2 Cluster: Uncharacterized protein YER023C-A; n=2;
Saccharomycetaceae|Rep: Uncharacterized protein
YER023C-A - Saccharomyces cerevisiae (Baker's yeast)
Length = 70
Score = 39.5 bits (88), Expect = 0.085
Identities = 21/45 (46%), Positives = 29/45 (64%)
Frame = +3
Query: 330 GKPQRTPPSARDSISM*T*AGPLPLRAVIASIWYSGTSSQVPTAL 464
G P P S +DS T AGP P +AV AS+++SG+S+ +PT L
Sbjct: 10 GIPNFNPLSIKDSNIKRTKAGPEPTKAVAASMFFSGSSTYLPTWL 54
>UniRef50_UPI0000DAE5EB Cluster: hypothetical protein
Rgryl_01000761; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000761 - Rickettsiella
grylli
Length = 138
Score = 38.3 bits (85), Expect = 0.20
Identities = 22/53 (41%), Positives = 32/53 (60%), Gaps = 1/53 (1%)
Frame = -3
Query: 676 EIKNLPSAKNKLFISVAMGITIATVESNLPSE-ARVIRVMPNTPALVKEGAAA 521
EI +N L IS+A+GI + +E+ L ++ +IR MPNTPAL+ A A
Sbjct: 81 EIAKCMQERNPLVISIAVGIRLNHLENYLLNQNLALIRCMPNTPALIGCAATA 133
>UniRef50_Q3K4H0 Cluster: Rhs element Vgr protein precursor; n=4;
Pseudomonas|Rep: Rhs element Vgr protein precursor -
Pseudomonas fluorescens (strain PfO-1)
Length = 1118
Score = 35.9 bits (79), Expect = 1.0
Identities = 12/39 (30%), Positives = 24/39 (61%)
Frame = +2
Query: 98 GLIVQLFFYNLTSIYCRRHCTDYGRTETVFLQVICSLSG 214
G++V F +++ + R +CT YG ++ F+Q +C+ G
Sbjct: 126 GILVDAFTFHVQPLVAREYCTQYGESDFEFIQRLCAEEG 164
>UniRef50_A2C5X0 Cluster: Putative uncharacterized protein; n=1;
Prochlorococcus marinus str. MIT 9303|Rep: Putative
uncharacterized protein - Prochlorococcus marinus
(strain MIT 9303)
Length = 531
Score = 35.1 bits (77), Expect = 1.8
Identities = 31/111 (27%), Positives = 47/111 (42%), Gaps = 2/111 (1%)
Frame = -3
Query: 541 VKEGAAAFSRGTKATAEDAQLTSQLFKAVGTCDEVPEYQMDAITALSGSGPAYVYMLIES 362
+ G+ F G K T + + +QL VG Y D+ITAL+ G VY
Sbjct: 187 ITAGSTPFIGGGKGT-DSISIATQLGTIVGG------YGADSITALAAFGGGIVYGDANG 239
Query: 361 LADGGVRCGLPRDLALRL--AAQTTLGSAAMVKTGDHPAMLKDNVTSPAGS 215
+ GG G D A R+ +A T G+ + G + + N + AG+
Sbjct: 240 VTTGGTGTGTSADGADRISFSAGTVSGATTVYSGGGNDIITTANTSGTAGT 290
>UniRef50_Q57Z15 Cluster: Putative uncharacterized protein; n=1;
Trypanosoma brucei|Rep: Putative uncharacterized protein
- Trypanosoma brucei
Length = 585
Score = 34.3 bits (75), Expect = 3.2
Identities = 24/88 (27%), Positives = 42/88 (47%), Gaps = 5/88 (5%)
Frame = -3
Query: 619 ITIATVESNLPSEARVIRVMPNTPALV-----KEGAAAFSRGTKATAEDAQLTSQLFKAV 455
+ ++T+ S LP++A ++ +P T V E + S G AT D+ + +A
Sbjct: 341 LQLSTISSLLPTDADIVAQLPTTSLCVFADEDPEQSGELSSGFHATKRDS--GDHVLRAA 398
Query: 454 GTCDEVPEYQMDAITALSGSGPAYVYML 371
D+V E + A+T SG P ++ L
Sbjct: 399 AATDDV-EVESHAVTPTSGGEPPLLHPL 425
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 763,955,187
Number of Sequences: 1657284
Number of extensions: 16485635
Number of successful extensions: 39483
Number of sequences better than 10.0: 260
Number of HSP's better than 10.0 without gapping: 37720
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39181
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 60500186565
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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