Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12b21f
(609 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protei... 79 1e-14
AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligas... 77 6e-14
D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein. 64 5e-10
BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein. 64 5e-10
AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein. 64 5e-10
BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4 p... 62 2e-09
AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containin... 62 2e-09
AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containin... 62 2e-09
AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4 p... 62 2e-09
AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4 p... 62 2e-09
AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein. 61 3e-09
BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome... 59 1e-08
AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation... 59 1e-08
AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome... 59 1e-08
AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging ... 59 1e-08
AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging ... 59 1e-08
U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein. 58 2e-08
AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein. 57 6e-08
BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6 p... 56 7e-08
AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein. 56 7e-08
AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein. 56 7e-08
AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant pr... 56 7e-08
AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein. 56 7e-08
BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein. 56 1e-07
AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome... 56 1e-07
AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide exch... 56 1e-07
AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein. 56 1e-07
BC142946-1|AAI42947.1| 457|Homo sapiens RCC2 protein protein. 56 1e-07
BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating gu... 56 1e-07
BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein. 56 1e-07
BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome... 56 1e-07
AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein pr... 56 1e-07
AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein. 56 1e-07
AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associat... 56 1e-07
AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associat... 56 1e-07
AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein. 56 1e-07
AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containin... 54 3e-07
AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein. 54 3e-07
BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein. 53 7e-07
AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4 p... 52 1e-06
AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4 p... 52 1e-06
X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein. 52 2e-06
U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPa... 52 2e-06
BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein. 52 2e-06
AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa GT... 52 2e-06
AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa GT... 52 2e-06
AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein. 52 2e-06
AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens ... 51 3e-06
AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein. 51 3e-06
AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa GT... 51 4e-06
AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein. 50 8e-06
AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein. 50 8e-06
AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein. 50 8e-06
AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with... 50 8e-06
AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containin... 48 2e-05
BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis ... 46 8e-05
BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8 p... 46 8e-05
AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8... 46 8e-05
AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a... 46 8e-05
X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for ... 45 2e-04
X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for ... 45 2e-04
D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein. 45 2e-04
DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's t... 45 2e-04
DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's t... 45 2e-04
CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein. 45 2e-04
BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton aga... 45 2e-04
BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton aga... 45 2e-04
BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome... 45 2e-04
BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome... 45 2e-04
BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome... 45 2e-04
BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome... 45 2e-04
AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome... 45 2e-04
AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein. 45 2e-04
AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome... 45 2e-04
AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein. 45 2e-04
BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein. 44 3e-04
BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein. 43 7e-04
BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein. 43 7e-04
BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrom... 43 7e-04
BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrom... 43 7e-04
AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging ... 43 7e-04
BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9 p... 42 0.002
BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis ... 42 0.002
AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERC... 42 0.002
AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek... 42 0.002
AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens ... 42 0.002
AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein. 42 0.002
BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein. 41 0.004
BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein. 41 0.004
AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein. 41 0.004
AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein. 41 0.004
AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein. 41 0.004
AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein. 41 0.004
AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens ... 39 0.012
AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein. 39 0.012
BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein. 38 0.028
AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2 pro... 38 0.037
BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein. 32 1.4
AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein. 32 1.4
AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein. 32 1.4
AB051514-1|BAB21818.1| 1130|Homo sapiens KIAA1727 protein protein. 30 5.5
>AB027289-1|BAA88519.1| 1024|Homo sapiens cyclin-E binding protein 1
protein.
Length = 1024
Score = 79.0 bits (186), Expect = 1e-14
Identities = 59/176 (33%), Positives = 87/176 (49%), Gaps = 5/176 (2%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + E + G NL Q L +G+ S TP VE HSM
Sbjct: 148 YHSLALSKGGELFAWGQNLHGQ--LGVGRKFPSTT-TPQIVEHLAGVPLAQISAGEAHSM 204
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
ALS G++Y WG N+ GQLG+ +E S P L++ DN++V +ACG HS
Sbjct: 205 ALSMSGNIYSWGKNECGQLGLGHTE----SKDDPSLIEGL-DNQKVEF----VACGGSHS 255
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE-----ACRLKCGPWTTV 571
LL +DG ++T GA K+GQL + +++N + C++ E ++ CG W T+
Sbjct: 256 ALLTQDGLLFTFGAGKHGQLG---HNSTQNELRPCLVAELVGYRVTQIACGRWHTL 308
Score = 30.3 bits (65), Expect = 5.5
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +2
Query: 383 QIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+I I CG HS+ L + G ++ G N +GQL
Sbjct: 139 KIIQITCGDYHSLALSKGGELFAWGQNLHGQL 170
>AY337518-1|AAR00320.1| 1024|Homo sapiens HECT E3 ubiquitin ligase
protein.
Length = 1024
Score = 76.6 bits (180), Expect = 6e-14
Identities = 58/176 (32%), Positives = 86/176 (48%), Gaps = 5/176 (2%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + E + G NL Q L +G+ S TP VE HS
Sbjct: 148 YHSLALSKGGELFAWGQNLHGQ--LGVGRKFPSTT-TPQIVEHLAGVPLAQISAGEAHST 204
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
ALS G++Y WG N+ GQLG+ +E S P L++ D N++V +ACG HS
Sbjct: 205 ALSMSGNIYSWGKNECGQLGLGHTE----SKDDPSLIEGLD-NQKVEF----VACGGSHS 255
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE-----ACRLKCGPWTTV 571
LL +DG ++T GA K+GQL + +++N + C++ E ++ CG W T+
Sbjct: 256 ALLTQDGLLFTFGAGKHGQLG---HNSTQNELRPCLVAELVGYRVTQIACGRWHTL 308
Score = 30.3 bits (65), Expect = 5.5
Identities = 13/32 (40%), Positives = 19/32 (59%)
Frame = +2
Query: 383 QIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+I I CG HS+ L + G ++ G N +GQL
Sbjct: 139 KIIQITCGDYHSLALSKGGELFAWGQNLHGQL 170
>D25215-1|BAA04945.2| 1054|Homo sapiens KIAA0032 protein.
Length = 1054
Score = 63.7 bits (148), Expect = 5e-10
Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 1/145 (0%)
Frame = +2
Query: 89 EYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYV 268
E Y G N + QLG + N P Q+ HS+ALS+ G L+
Sbjct: 58 EVYTCGLNT----KGQLGHEREGN--KPEQIGALADQHIIHVACGESHSLALSDRGQLFS 111
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQLG+ +E+ S A+P+L+ N++ LQ ++CG+ H + L DG +
Sbjct: 112 WGAGSDGQLGLMTTED---SVAVPRLIQKL--NQQTILQ---VSCGNWHCLALAADGQFF 163
Query: 449 TTGANKYGQLAC-PQYPNSKNFNKV 520
T G N +GQL ++P+ + +V
Sbjct: 164 TWGKNSHGQLGLGKEFPSQASPQRV 188
Score = 63.3 bits (147), Expect = 6e-10
Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 2/166 (1%)
Frame = +2
Query: 65 CLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMAL 244
CL +++ G N Q L LG++ S +P +V HS AL
Sbjct: 153 CLALAADGQFFTWGKNSHGQ--LGLGKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFAL 209
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
S G ++ WG+N+ GQLG+ + E D +S P V L + V+ I+CG +H+ +
Sbjct: 210 SLSGAVFGWGMNNAGQLGLSD-EKDRES---PCHVKLLRTQKVVY-----ISCGEEHTAV 260
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVI--KEACRLKCG 556
L + G V+T GA GQL + N +V + E ++ CG
Sbjct: 261 LTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACG 306
Score = 50.0 bits (114), Expect = 6e-06
Identities = 30/70 (42%), Positives = 36/70 (51%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQ GI S N A P++ D +K++ACG HSV LLEDG V+
Sbjct: 8 WGYWSLGQPGI--STNLQGIVAEPQVCGFISDRS-----VKEVACGGNHSVFLLEDGEVY 60
Query: 449 TTGANKYGQL 478
T G N GQL
Sbjct: 61 TCGLNTKGQL 70
Score = 47.6 bits (108), Expect = 3e-05
Identities = 29/83 (34%), Positives = 42/83 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ L E G++Y GLN GQLG + N P+ + D +H +ACG
Sbjct: 49 HSVFLLEDGEVYTCGLNTKGQLGHEREGNK------PEQIGALADQHIIH-----VACGE 97
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
HS+ L + G +++ GA GQL
Sbjct: 98 SHSLALSDRGQLFSWGAGSDGQL 120
>BC038960-1|AAH38960.1| 368|Homo sapiens HERC3 protein protein.
Length = 368
Score = 63.7 bits (148), Expect = 5e-10
Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 1/145 (0%)
Frame = +2
Query: 89 EYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYV 268
E Y G N + QLG + N P Q+ HS+ALS+ G L+
Sbjct: 54 EVYTCGLNT----KGQLGHEREGN--KPEQIGALADQHIIHVACGESHSLALSDRGQLFS 107
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQLG+ +E+ S A+P+L+ N++ LQ ++CG+ H + L DG +
Sbjct: 108 WGAGSDGQLGLMTTED---SVAVPRLIQKL--NQQTILQ---VSCGNWHCLALAADGQFF 159
Query: 449 TTGANKYGQLAC-PQYPNSKNFNKV 520
T G N +GQL ++P+ + +V
Sbjct: 160 TWGKNSHGQLGLGKEFPSQASPQRV 184
Score = 63.3 bits (147), Expect = 6e-10
Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 2/166 (1%)
Frame = +2
Query: 65 CLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMAL 244
CL +++ G N Q L LG++ S +P +V HS AL
Sbjct: 149 CLALAADGQFFTWGKNSHGQ--LGLGKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFAL 205
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
S G ++ WG+N+ GQLG+ + E D +S P V L + V+ I+CG +H+ +
Sbjct: 206 SLSGAVFGWGMNNAGQLGLSD-EKDRES---PCHVKLLRTQKVVY-----ISCGEEHTAV 256
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVI--KEACRLKCG 556
L + G V+T GA GQL + N +V + E ++ CG
Sbjct: 257 LTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACG 302
Score = 50.0 bits (114), Expect = 6e-06
Identities = 30/70 (42%), Positives = 36/70 (51%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQ GI S N A P++ D +K++ACG HSV LLEDG V+
Sbjct: 4 WGYWSLGQPGI--STNLQGIVAEPQVCGFISDRS-----VKEVACGGNHSVFLLEDGEVY 56
Query: 449 TTGANKYGQL 478
T G N GQL
Sbjct: 57 TCGLNTKGQL 66
Score = 47.6 bits (108), Expect = 3e-05
Identities = 29/83 (34%), Positives = 42/83 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ L E G++Y GLN GQLG + N P+ + D +H +ACG
Sbjct: 45 HSVFLLEDGEVYTCGLNTKGQLGHEREGNK------PEQIGALADQHIIH-----VACGE 93
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
HS+ L + G +++ GA GQL
Sbjct: 94 SHSLALSDRGQLFSWGAGSDGQL 116
>AC098582-1|AAY41038.1| 382|Homo sapiens unknown protein.
Length = 382
Score = 63.7 bits (148), Expect = 5e-10
Identities = 45/145 (31%), Positives = 70/145 (48%), Gaps = 1/145 (0%)
Frame = +2
Query: 89 EYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYV 268
E Y G N + QLG + N P Q+ HS+ALS+ G L+
Sbjct: 54 EVYTCGLNT----KGQLGHEREGN--KPEQIGALADQHIIHVACGESHSLALSDRGQLFS 107
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQLG+ +E+ S A+P+L+ N++ LQ ++CG+ H + L DG +
Sbjct: 108 WGAGSDGQLGLMTTED---SVAVPRLIQKL--NQQTILQ---VSCGNWHCLALAADGQFF 159
Query: 449 TTGANKYGQLAC-PQYPNSKNFNKV 520
T G N +GQL ++P+ + +V
Sbjct: 160 TWGKNSHGQLGLGKEFPSQASPQRV 184
Score = 63.3 bits (147), Expect = 6e-10
Identities = 49/166 (29%), Positives = 76/166 (45%), Gaps = 2/166 (1%)
Frame = +2
Query: 65 CLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMAL 244
CL +++ G N Q L LG++ S +P +V HS AL
Sbjct: 149 CLALAADGQFFTWGKNSHGQ--LGLGKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSFAL 205
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
S G ++ WG+N+ GQLG+ + E D +S P V L + V+ I+CG +H+ +
Sbjct: 206 SLSGAVFGWGMNNAGQLGLSD-EKDRES---PCHVKLLRTQKVVY-----ISCGEEHTAV 256
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVI--KEACRLKCG 556
L + G V+T GA GQL + N +V + E ++ CG
Sbjct: 257 LTKSGGVFTFGAGSCGQLGHDSMNDEVNPRRVLELMGSEVTQIACG 302
Score = 50.0 bits (114), Expect = 6e-06
Identities = 30/70 (42%), Positives = 36/70 (51%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQ GI S N A P++ D +K++ACG HSV LLEDG V+
Sbjct: 4 WGYWSLGQPGI--STNLQGIVAEPQVCGFISDRS-----VKEVACGGNHSVFLLEDGEVY 56
Query: 449 TTGANKYGQL 478
T G N GQL
Sbjct: 57 TCGLNTKGQL 66
Score = 47.6 bits (108), Expect = 3e-05
Identities = 29/83 (34%), Positives = 42/83 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ L E G++Y GLN GQLG + N P+ + D +H +ACG
Sbjct: 45 HSVFLLEDGEVYTCGLNTKGQLGHEREGNK------PEQIGALADQHIIH-----VACGE 93
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
HS+ L + G +++ GA GQL
Sbjct: 94 SHSLALSDRGQLFSWGAGSDGQL 116
>BC039600-1|AAH39600.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/115 (33%), Positives = 58/115 (50%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG + + + P QV H++AL++ G +Y WGL+ GQLG+ SE
Sbjct: 65 QLGHEKSR--KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSE 122
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ +P+ + D +QI +ACG HS+ L + V+ G NKYGQL
Sbjct: 123 ECIR---VPRNIKSLSD-----IQIVQVACGYYHSLALSKASEVFCWGQNKYGQL 169
Score = 54.4 bits (125), Expect = 3e-07
Identities = 46/154 (29%), Positives = 66/154 (42%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + E + G N + Q L LG D +P ++ HS
Sbjct: 147 YHSLALSKASEVFCWGQNKYGQ--LGLGTD-CKKQTSPQLLKSLLGIPFMQVAAGGAHSF 203
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
L+ G ++ WG N GQLG+ + END Y +P L+ + V+ I CG H+
Sbjct: 204 VLTLSGAIFGWGRNKFGQLGLND-END--RY-VPNLLKSLRSQKIVY-----ICCGEDHT 254
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKV 520
L ++G V+T GA YGQL + N KV
Sbjct: 255 AALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKV 288
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/70 (32%), Positives = 41/70 (58%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQLG+ + ++ P+ D + ++ +++D+ CG +H+V +L+DG+V+
Sbjct: 4 WGNASFGQLGLGGIDEEI--VLEPRKSDFF-----INKRVRDVGCGLRHTVFVLDDGTVY 56
Query: 449 TTGANKYGQL 478
T G N GQL
Sbjct: 57 TCGCNDLGQL 66
>AY650033-1|AAV66579.1| 979|Homo sapiens HECT and RCC1 containing
protein 4 isoform 3 protein.
Length = 979
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/115 (33%), Positives = 58/115 (50%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG + + + P QV H++AL++ G +Y WGL+ GQLG+ SE
Sbjct: 65 QLGHEKSR--KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSE 122
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ +P+ + D +QI +ACG HS+ L + V+ G NKYGQL
Sbjct: 123 ECIR---VPRNIKSLSD-----IQIVQVACGYYHSLALSKASEVFCWGQNKYGQL 169
Score = 54.4 bits (125), Expect = 3e-07
Identities = 46/154 (29%), Positives = 66/154 (42%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + E + G N + Q L LG D +P ++ HS
Sbjct: 147 YHSLALSKASEVFCWGQNKYGQ--LGLGTD-CKKQTSPQLLKSLLGIPFMQVAAGGAHSF 203
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
L+ G ++ WG N GQLG+ + END Y +P L+ + V+ I CG H+
Sbjct: 204 VLTLSGAIFGWGRNKFGQLGLND-END--RY-VPNLLKSLRSQKIVY-----ICCGEDHT 254
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKV 520
L ++G V+T GA YGQL + N KV
Sbjct: 255 AALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKV 288
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/70 (32%), Positives = 41/70 (58%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQLG+ + ++ P+ D + ++ +++D+ CG +H+V +L+DG+V+
Sbjct: 4 WGNASFGQLGLGGIDEEI--VLEPRKSDFF-----INKRVRDVGCGLRHTVFVLDDGTVY 56
Query: 449 TTGANKYGQL 478
T G N GQL
Sbjct: 57 TCGCNDLGQL 66
>AY221963-1|AAO65480.1| 1057|Homo sapiens HECT and RCC1 containing
protein 4 isoform 1 protein.
Length = 1057
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/115 (33%), Positives = 58/115 (50%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG + + + P QV H++AL++ G +Y WGL+ GQLG+ SE
Sbjct: 65 QLGHEKSR--KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSE 122
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ +P+ + D +QI +ACG HS+ L + V+ G NKYGQL
Sbjct: 123 ECIR---VPRNIKSLSD-----IQIVQVACGYYHSLALSKASEVFCWGQNKYGQL 169
Score = 54.4 bits (125), Expect = 3e-07
Identities = 46/154 (29%), Positives = 66/154 (42%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + E + G N + Q L LG D +P ++ HS
Sbjct: 147 YHSLALSKASEVFCWGQNKYGQ--LGLGTD-CKKQTSPQLLKSLLGIPFMQVAAGGAHSF 203
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
L+ G ++ WG N GQLG+ + END Y +P L+ + V+ I CG H+
Sbjct: 204 VLTLSGAIFGWGRNKFGQLGLND-END--RY-VPNLLKSLRSQKIVY-----ICCGEDHT 254
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKV 520
L ++G V+T GA YGQL + N KV
Sbjct: 255 AALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKV 288
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/70 (32%), Positives = 41/70 (58%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQLG+ + ++ P+ D + ++ +++D+ CG +H+V +L+DG+V+
Sbjct: 4 WGNASFGQLGLGGIDEEI--VLEPRKSDFF-----INKRVRDVGCGLRHTVFVLDDGTVY 56
Query: 449 TTGANKYGQL 478
T G N GQL
Sbjct: 57 TCGCNDLGQL 66
>AL356741-3|CAH74148.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/115 (33%), Positives = 58/115 (50%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG + + + P QV H++AL++ G +Y WGL+ GQLG+ SE
Sbjct: 65 QLGHEKSR--KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSE 122
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ +P+ + D +QI +ACG HS+ L + V+ G NKYGQL
Sbjct: 123 ECIR---VPRNIKSLSD-----IQIVQVACGYYHSLALSKASEVFCWGQNKYGQL 169
Score = 54.4 bits (125), Expect = 3e-07
Identities = 46/154 (29%), Positives = 66/154 (42%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + E + G N + Q L LG D +P ++ HS
Sbjct: 147 YHSLALSKASEVFCWGQNKYGQ--LGLGTD-CKKQTSPQLLKSLLGIPFMQVAAGGAHSF 203
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
L+ G ++ WG N GQLG+ + END Y +P L+ + V+ I CG H+
Sbjct: 204 VLTLSGAIFGWGRNKFGQLGLND-END--RY-VPNLLKSLRSQKIVY-----ICCGEDHT 254
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKV 520
L ++G V+T GA YGQL + N KV
Sbjct: 255 AALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKV 288
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/70 (32%), Positives = 41/70 (58%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQLG+ + ++ P+ D + ++ +++D+ CG +H+V +L+DG+V+
Sbjct: 4 WGNASFGQLGLGGIDEEI--VLEPRKSDFF-----INKRVRDVGCGLRHTVFVLDDGTVY 56
Query: 449 TTGANKYGQL 478
T G N GQL
Sbjct: 57 TCGCNDLGQL 66
>AL133551-3|CAI16032.1| 1049|Homo sapiens hect domain and RLD 4
protein.
Length = 1049
Score = 61.7 bits (143), Expect = 2e-09
Identities = 38/115 (33%), Positives = 58/115 (50%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG + + + P QV H++AL++ G +Y WGL+ GQLG+ SE
Sbjct: 65 QLGHEKSR--KKPEQVVALDAQNIVAVSCGEAHTLALNDKGQVYAWGLDSDGQLGLVGSE 122
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ +P+ + D +QI +ACG HS+ L + V+ G NKYGQL
Sbjct: 123 ECIR---VPRNIKSLSD-----IQIVQVACGYYHSLALSKASEVFCWGQNKYGQL 169
Score = 54.4 bits (125), Expect = 3e-07
Identities = 46/154 (29%), Positives = 66/154 (42%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + E + G N + Q L LG D +P ++ HS
Sbjct: 147 YHSLALSKASEVFCWGQNKYGQ--LGLGTD-CKKQTSPQLLKSLLGIPFMQVAAGGAHSF 203
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
L+ G ++ WG N GQLG+ + END Y +P L+ + V+ I CG H+
Sbjct: 204 VLTLSGAIFGWGRNKFGQLGLND-END--RY-VPNLLKSLRSQKIVY-----ICCGEDHT 254
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKV 520
L ++G V+T GA YGQL + N KV
Sbjct: 255 AALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKV 288
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/70 (32%), Positives = 41/70 (58%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQLG+ + ++ P+ D + ++ +++D+ CG +H+V +L+DG+V+
Sbjct: 4 WGNASFGQLGLGGIDEEI--VLEPRKSDFF-----INKRVRDVGCGLRHTVFVLDDGTVY 56
Query: 449 TTGANKYGQL 478
T G N GQL
Sbjct: 57 TCGCNDLGQL 66
>AF071172-1|AAD08657.1| 4834|Homo sapiens HERC2 protein.
Length = 4834
Score = 60.9 bits (141), Expect = 3e-09
Identities = 38/117 (32%), Positives = 57/117 (48%), Gaps = 2/117 (1%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG + S + P +E HS ++ GDLY WG G+LG +SE
Sbjct: 4070 KLGHGNRSPCDRPRVIESLRGIEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRLGHSDSE 4129
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGS--KHSVLLLEDGSVWTTGANKYGQL 478
+ LK PKLV+ + ++ DIACGS ++ L +D +VW+ G YG+L
Sbjct: 4130 DQLK----PKLVEALQGH-----RVVDIACGSGDAQTLCLTDDDTVWSWGDGDYGKL 4177
Score = 52.0 bits (119), Expect = 2e-06
Identities = 26/83 (31%), Positives = 43/83 (51%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +AL+ G++Y WG D G+LG D PK++ + ++ + IACGS
Sbjct: 506 HYLALAATGEVYSWGCGDGGRLG----HGDTVPLEEPKVISAFS-GKQAGKHVVHIACGS 560
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
+S + +G ++T G YG+L
Sbjct: 561 TYSAAITAEGELYTWGRGNYGRL 583
Score = 51.2 bits (117), Expect = 3e-06
Identities = 33/117 (28%), Positives = 57/117 (48%), Gaps = 2/117 (1%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG N + P +E HS AL+ G+LY WGL + G+LG ++
Sbjct: 3078 KLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNT 3137
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK--HSVLLLEDGSVWTTGANKYGQL 478
LK PK+V + + ++ +ACGS+ ++ L ++G V++ G +G+L
Sbjct: 3138 TQLK----PKMVKVL-----LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKL 3185
Score = 50.0 bits (114), Expect = 6e-06
Identities = 37/121 (30%), Positives = 57/121 (47%), Gaps = 6/121 (4%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXX----XWHSMALSEFGDLYVWGLNDTGQLGI 301
+LG DT LE P + +S A++ G+LY WG + G+LG
Sbjct: 526 RLGHGDTVPLEEPKVISAFSGKQAGKHVVHIACGSTYSAAITAEGELYTWGRGNYGRLGH 585
Query: 302 KESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS--KHSVLLLEDGSVWTTGANKYGQ 475
SE++ A+P LV L++ D+ACGS ++ + E+G VW+ G YG+
Sbjct: 586 GSSEDE----AIPMLVAGLKG-----LKVIDVACGSGDAQTLAVTENGQVWSWGDGDYGK 636
Query: 476 L 478
L
Sbjct: 637 L 637
Score = 45.6 bits (103), Expect = 1e-04
Identities = 30/117 (25%), Positives = 53/117 (45%), Gaps = 2/117 (1%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXW--HSMALSEFGDLYVWGLNDTGQLGIKE 307
+LG T ++ TPT +E H +ALS G++Y WG + G+LG
Sbjct: 4016 RLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLG--- 4072
Query: 308 SENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+ P++++ +++ D+A G HS + G ++T G +YG+L
Sbjct: 4073 -HGNRSPCDRPRVIESLRG-----IEVVDVAAGGAHSACVTAAGDLYTWGKGRYGRL 4123
Score = 43.6 bits (98), Expect = 6e-04
Identities = 30/110 (27%), Positives = 49/110 (44%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG+ + +TP +E S+AL++ G +Y WG D +LG E
Sbjct: 636 KLGRGGSDGCKTPKLIEKLQDLDVVKVRCGSQFSIALTKDGQVYSWGKGDNQRLGHGTEE 695
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGAN 463
+ PKL++ + + D+A GS H + L ED V + G+N
Sbjct: 696 H----VRYPKLLEGLQGKKVI-----DVAAGSTHCLALTEDSEVHSWGSN 736
Score = 43.2 bits (97), Expect = 7e-04
Identities = 32/115 (27%), Positives = 52/115 (45%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG+ + + P +++ S+AL++ G +Y WG D +LG S+
Sbjct: 4176 KLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLG-HGSD 4234
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+ ++ P+ V + + IA GS H V EDG V+T G N GQL
Sbjct: 4235 DHVRR---PRQVQGLQGKKVIA-----IATGSLHCVCCTEDGEVYTWGDNDEGQL 4281
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/96 (26%), Positives = 41/96 (42%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG ++ P QV+ H + +E G++Y WG ND GQLG +
Sbjct: 4228 RLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLG----D 4283
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSV 421
+ P+LV ++ +ACGS H++
Sbjct: 4284 GTTNAIQRPRLVAALQGK-----KVNRVACGSAHTL 4314
Score = 41.9 bits (94), Expect = 0.002
Identities = 24/75 (32%), Positives = 43/75 (57%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK 412
++A++E G ++ WG D G+LG + + K+ PKL++ D L + + CGS+
Sbjct: 617 TLAVTENGQVWSWGDGDYGKLG-RGGSDGCKT---PKLIEKLQD-----LDVVKVRCGSQ 667
Query: 413 HSVLLLEDGSVWTTG 457
S+ L +DG V++ G
Sbjct: 668 FSIALTKDGQVYSWG 682
Score = 39.1 bits (87), Expect = 0.012
Identities = 28/96 (29%), Positives = 41/96 (42%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG ++ P VE H +A+++ G +Y WG ND GQ G +
Sbjct: 3236 RLGHGSDVHVRKPQVVEGLRGKKIVHVAVGALHCLAVTDSGQVYAWGDNDHGQQGNGTTT 3295
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSV 421
+ K P LV + + I +ACGS HSV
Sbjct: 3296 VNRK----PTLVQGLEGQK-----ITRVACGSSHSV 3322
Score = 36.3 bits (80), Expect = 0.084
Identities = 24/82 (29%), Positives = 42/82 (51%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK 412
++AL++ G ++ WG D G+LG SE +P+ ++ + + I CG++
Sbjct: 3165 TLALTDEGLVFSWGDGDFGKLGRGGSEG----CNIPQNIERLNGQG-----VCQIECGAQ 3215
Query: 413 HSVLLLEDGSVWTTGANKYGQL 478
S+ L + G VWT G Y +L
Sbjct: 3216 FSLALTKSGVVWTWGKGDYFRL 3237
>BC029052-1|AAH29052.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 59.3 bits (137), Expect = 1e-08
Identities = 33/100 (33%), Positives = 51/100 (51%)
Frame = +2
Query: 236 MALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKH 415
MA+ + G++YVWG N GQLG+ S N + L + +++ +ACG H
Sbjct: 218 MAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGI---------RVQRVACGYAH 268
Query: 416 SVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE 535
+++L ++G V+ GAN YGQL N V V K+
Sbjct: 269 TLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKD 308
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 3/173 (1%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXWHSMAL 244
+L TT E + G N ++Q LG T++ P + +HS+ L
Sbjct: 112 VLATTEGEVFTWGHNAYSQ----LGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVL 167
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+ G+++ WG N++GQ+G + N +P+ V N+ V IACG +
Sbjct: 168 TSDGEVFAWGYNNSGQVGSGSTVNQ----PIPRRVTGCLQNKVV----VTIACGQMCCMA 219
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIK--EACRLKCGPWTTVVV 577
+++ G V+ G N GQL N +V ++ R+ CG T+V+
Sbjct: 220 VVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVL 272
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/96 (31%), Positives = 41/96 (42%)
Frame = +2
Query: 65 CLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMAL 244
C+ T E YV G N QLG ++ N TP +V H++ L
Sbjct: 217 CMAVVDTGEVYVWGYN----GNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVL 272
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVD 352
++ G +Y WG N GQLG N +SY P V+
Sbjct: 273 TDEGQVYAWGANSYGQLGTGNKSN--QSYPTPVTVE 306
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/83 (31%), Positives = 42/83 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + + G+++ WG N QLG N ++ L V + + Q+ ++ACGS
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLG-----NGTTNHGL---VPCHISTNLSNKQVIEVACGS 161
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
HS++L DG V+ G N GQ+
Sbjct: 162 YHSLVLTSDGEVFAWGYNNSGQV 184
>AY341245-1|AAP88928.1| 551|Homo sapiens chromosome condensation
1-like protein.
Length = 551
Score = 59.3 bits (137), Expect = 1e-08
Identities = 33/100 (33%), Positives = 51/100 (51%)
Frame = +2
Query: 236 MALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKH 415
MA+ + G++YVWG N GQLG+ S N + L + +++ +ACG H
Sbjct: 218 MAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGI---------RVQRVACGYAH 268
Query: 416 SVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE 535
+++L ++G V+ GAN YGQL N V V K+
Sbjct: 269 TLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKD 308
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 3/173 (1%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXWHSMAL 244
+L TT E + G N ++Q LG T++ P + +HS+ L
Sbjct: 112 VLATTEGEVFTWGHNAYSQ----LGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVL 167
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+ G+++ WG N++GQ+G + N +P+ V N+ V IACG +
Sbjct: 168 TSDGEVFAWGYNNSGQVGSGSTVNQ----PIPRRVTGCLQNKVV----VTIACGQMCCMA 219
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIK--EACRLKCGPWTTVVV 577
+++ G V+ G N GQL N +V ++ R+ CG T+V+
Sbjct: 220 VVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVL 272
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/96 (31%), Positives = 41/96 (42%)
Frame = +2
Query: 65 CLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMAL 244
C+ T E YV G N QLG ++ N TP +V H++ L
Sbjct: 217 CMAVVDTGEVYVWGYN----GNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVL 272
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVD 352
++ G +Y WG N GQLG N +SY P V+
Sbjct: 273 TDEGQVYAWGANSYGQLGTGNKSN--QSYPTPVTVE 306
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/83 (31%), Positives = 42/83 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + + G+++ WG N QLG N ++ L V + + Q+ ++ACGS
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLG-----NGTTNHGL---VPCHISTNLSNKQVIEVACGS 161
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
HS++L DG V+ G N GQ+
Sbjct: 162 YHSLVLTSDGEVFAWGYNNSGQV 184
>AL157813-1|CAH70795.1| 551|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 551
Score = 59.3 bits (137), Expect = 1e-08
Identities = 33/100 (33%), Positives = 51/100 (51%)
Frame = +2
Query: 236 MALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKH 415
MA+ + G++YVWG N GQLG+ S N + L + +++ +ACG H
Sbjct: 218 MAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGI---------RVQRVACGYAH 268
Query: 416 SVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE 535
+++L ++G V+ GAN YGQL N V V K+
Sbjct: 269 TLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKD 308
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 3/173 (1%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXWHSMAL 244
+L TT E + G N ++Q LG T++ P + +HS+ L
Sbjct: 112 VLATTEGEVFTWGHNAYSQ----LGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVL 167
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+ G+++ WG N++GQ+G + N +P+ V N+ V IACG +
Sbjct: 168 TSDGEVFAWGYNNSGQVGSGSTVNQ----PIPRRVTGCLQNKVV----VTIACGQMCCMA 219
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIK--EACRLKCGPWTTVVV 577
+++ G V+ G N GQL N +V ++ R+ CG T+V+
Sbjct: 220 VVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVL 272
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/96 (31%), Positives = 41/96 (42%)
Frame = +2
Query: 65 CLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMAL 244
C+ T E YV G N QLG ++ N TP +V H++ L
Sbjct: 217 CMAVVDTGEVYVWGYN----GNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVL 272
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVD 352
++ G +Y WG N GQLG N +SY P V+
Sbjct: 273 TDEGQVYAWGANSYGQLGTGNKSN--QSYPTPVTVE 306
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/83 (31%), Positives = 42/83 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + + G+++ WG N QLG N ++ L V + + Q+ ++ACGS
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLG-----NGTTNHGL---VPCHISTNLSNKQVIEVACGS 161
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
HS++L DG V+ G N GQ+
Sbjct: 162 YHSLVLTSDGEVFAWGYNNSGQV 184
>AF060219-1|AAC79987.1| 551|Homo sapiens RCC1-like G exchanging
factor RLG protein.
Length = 551
Score = 59.3 bits (137), Expect = 1e-08
Identities = 33/100 (33%), Positives = 51/100 (51%)
Frame = +2
Query: 236 MALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKH 415
MA+ + G++YVWG N GQLG+ S N + L + +++ +ACG H
Sbjct: 218 MAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGI---------RVQRVACGYAH 268
Query: 416 SVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE 535
+++L ++G V+ GAN YGQL N V V K+
Sbjct: 269 TLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKD 308
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 3/173 (1%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXWHSMAL 244
+L TT E + G N ++Q LG T++ P + +HS+ L
Sbjct: 112 VLATTEGEVFTWGHNAYSQ----LGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVL 167
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+ G+++ WG N++GQ+G + N +P+ V N+ V IACG +
Sbjct: 168 TSDGEVFAWGYNNSGQVGSGSTVNQ----PIPRRVTGCLQNKVV----VTIACGQMCCMA 219
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIK--EACRLKCGPWTTVVV 577
+++ G V+ G N GQL N +V ++ R+ CG T+V+
Sbjct: 220 VVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVL 272
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/96 (31%), Positives = 41/96 (42%)
Frame = +2
Query: 65 CLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMAL 244
C+ T E YV G N QLG ++ N TP +V H++ L
Sbjct: 217 CMAVVDTGEVYVWGYN----GNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVL 272
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVD 352
++ G +Y WG N GQLG N +SY P V+
Sbjct: 273 TDEGQVYAWGANSYGQLGTGNKSN--QSYPTPVTVE 306
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/83 (31%), Positives = 42/83 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + + G+++ WG N QLG N ++ L V + + Q+ ++ACGS
Sbjct: 110 HIVLATTEGEVFTWGHNAYSQLG-----NGTTNHGL---VPCHISTNLSNKQVIEVACGS 161
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
HS++L DG V+ G N GQ+
Sbjct: 162 YHSLVLTSDGEVFAWGYNNSGQV 184
>AB209543-1|BAD92780.1| 556|Homo sapiens RCC1-like G exchanging
factor RLG variant protein.
Length = 556
Score = 59.3 bits (137), Expect = 1e-08
Identities = 33/100 (33%), Positives = 51/100 (51%)
Frame = +2
Query: 236 MALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKH 415
MA+ + G++YVWG N GQLG+ S N + L + +++ +ACG H
Sbjct: 223 MAVVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGI---------RVQRVACGYAH 273
Query: 416 SVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE 535
+++L ++G V+ GAN YGQL N V V K+
Sbjct: 274 TLVLTDEGQVYAWGANSYGQLGTGNKSNQSYPTPVTVEKD 313
Score = 50.8 bits (116), Expect = 4e-06
Identities = 44/173 (25%), Positives = 75/173 (43%), Gaps = 3/173 (1%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXWHSMAL 244
+L TT E + G N ++Q LG T++ P + +HS+ L
Sbjct: 117 VLATTEGEVFTWGHNAYSQ----LGNGTTNHGLVPCHISTNLSNKQVIEVACGSYHSLVL 172
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+ G+++ WG N++GQ+G + N +P+ V N+ V IACG +
Sbjct: 173 TSDGEVFAWGYNNSGQVGSGSTVNQ----PIPRRVTGCLQNKVV----VTIACGQMCCMA 224
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIK--EACRLKCGPWTTVVV 577
+++ G V+ G N GQL N +V ++ R+ CG T+V+
Sbjct: 225 VVDTGEVYVWGYNGNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVL 277
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/96 (31%), Positives = 41/96 (42%)
Frame = +2
Query: 65 CLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMAL 244
C+ T E YV G N QLG ++ N TP +V H++ L
Sbjct: 222 CMAVVDTGEVYVWGYN----GNGQLGLGNSGNQPTPCRVAALQGIRVQRVACGYAHTLVL 277
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVD 352
++ G +Y WG N GQLG N +SY P V+
Sbjct: 278 TDEGQVYAWGANSYGQLGTGNKSN--QSYPTPVTVE 311
Score = 44.0 bits (99), Expect = 4e-04
Identities = 26/83 (31%), Positives = 42/83 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + + G+++ WG N QLG N ++ L V + + Q+ ++ACGS
Sbjct: 115 HIVLATTEGEVFTWGHNAYSQLG-----NGTTNHGL---VPCHISTNLSNKQVIEVACGS 166
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
HS++L DG V+ G N GQ+
Sbjct: 167 YHSLVLTSDGEVFAWGYNNSGQV 189
>U50078-1|AAD12586.1| 4861|Homo sapiens p532 protein.
Length = 4861
Score = 58.0 bits (134), Expect = 2e-08
Identities = 36/118 (30%), Positives = 60/118 (50%), Gaps = 2/118 (1%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HSMAL+E G+++ WG D G+LG S+ + P+ ++ E V + +CG
Sbjct: 4093 HSMALTESGEVFSWGDGDYGKLGHGNSDRQRR----PRQIEALQGEEVVQM-----SCGF 4143
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIK--EACRLKCGPWTTVVV 577
KHS ++ DG ++T G YG+L N K +V ++ + ++ CG T+ V
Sbjct: 4144 KHSAVVTSDGKLFTFGNGDYGRLGLGNTSNKKLPERVTALEGYQIGQVACGLNHTLAV 4201
Score = 53.6 bits (123), Expect = 5e-07
Identities = 40/139 (28%), Positives = 67/139 (48%), Gaps = 2/139 (1%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXW-HSMAL 244
L FTT E + G + + LG ++S + P ++ + HS A+
Sbjct: 471 LAFTTEGEVFSWGDGDYGK----LGHGNSSTQKYPKLIQGPLQGKVVVCVSAGYRHSAAV 526
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+E G+LY WG D G+LG D S +P LV +++ + +++CGS H++
Sbjct: 527 TEDGELYTWGEGDFGRLG----HGDSNSRNIPTLV------KDIS-NVGEVSCGSSHTIA 575
Query: 425 LLEDG-SVWTTGANKYGQL 478
L +DG +VW+ G G+L
Sbjct: 576 LSKDGRTVWSFGGGDNGKL 594
Score = 49.2 bits (112), Expect = 1e-05
Identities = 33/116 (28%), Positives = 51/116 (43%), Gaps = 1/116 (0%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG ++ P Q+E HS ++ G L+ +G D G+LG+ +
Sbjct: 4113 KLGHGNSDRQRRPRQIEALQGEEVVQMSCGFKHSAVVTSDGKLFTFGNGDYGRLGLGNTS 4172
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGS-VWTTGANKYGQL 478
N LP+ V + QI +ACG H++ + DGS VW G YG+L
Sbjct: 4173 NK----KLPERVTALEG-----YQIGQVACGLNHTLAVSADGSMVWAFGDGDYGKL 4219
Score = 43.6 bits (98), Expect = 6e-04
Identities = 32/114 (28%), Positives = 47/114 (41%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG DT+ + P +E S+AL+ G +Y WG LG SE
Sbjct: 593 KLGHGDTNRVYKPKVIEALQGMFIRKVCAGSQSSLALTSTGQVYAWGCG--ACLGCGSSE 650
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQ 475
+ PKL++ E +I D++ G H + L D V+ G N GQ
Sbjct: 651 ---ATALRPKLIE-----ELAATRIVDVSIGDSHCLALSHDNEVYAWGNNSMGQ 696
Score = 37.9 bits (84), Expect = 0.028
Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Frame = +2
Query: 116 FNQWRL-QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQ 292
F Q RL L + N P Q+ H++AL+ GD+Y WG N GQ
Sbjct: 4263 FGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQ 4322
Query: 293 LGI 301
LG+
Sbjct: 4323 LGL 4325
Score = 36.7 bits (81), Expect = 0.064
Identities = 26/115 (22%), Positives = 53/115 (46%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG +++ +P +++ S+AL++ G +Y +G + L +
Sbjct: 4218 KLGLGNSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRAR 4277
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
N + +P L + I+D+A G++H++ L +G V+ G+N GQL
Sbjct: 4278 NHNRPQQIPVLAGVI---------IEDVAVGAEHTLALASNGDVYAWGSNSEGQL 4323
Score = 34.3 bits (75), Expect = 0.34
Identities = 27/93 (29%), Positives = 39/93 (41%)
Frame = +2
Query: 242 LSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSV 421
+SE ++YVWG N + QL E L+ PKL + D + I G +
Sbjct: 368 VSETCEVYVWGSNSSHQLVEGTQEKILQ----PKLAPSFSD-------AQTIEAGQYCTF 416
Query: 422 LLLEDGSVWTTGANKYGQLACPQYPNSKNFNKV 520
++ DGSV G YG+L N K+
Sbjct: 417 VISTDGSVRACGKGSYGRLGLGDSNNQSTLKKL 449
Score = 33.5 bits (73), Expect = 0.60
Identities = 31/118 (26%), Positives = 45/118 (38%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALS 247
L T+T + Y G L G + + L P +E H +ALS
Sbjct: 627 LALTSTGQVYAWGCGAC----LGCGSSEATALR-PKLIEELAATRIVDVSIGDSHCLALS 681
Query: 248 EFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSV 421
++Y WG N GQ G S + PK V D + I+ I+ G+ HS+
Sbjct: 682 HDNEVYAWGNNSMGQCGQGNSTGPITK---PKKVSGLDG-----IAIQQISAGTSHSL 731
>AF225407-1|AAO27483.1| 409|Homo sapiens HERC2 protein.
Length = 409
Score = 56.8 bits (131), Expect = 6e-08
Identities = 33/85 (38%), Positives = 48/85 (56%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS ++ GDLY WG G+LG +SE+ LK PKLV+ + ++ DIACGS
Sbjct: 6 HSACVTAAGDLYTWGKGRYGRLGHSDSEDQLK----PKLVEALQGH-----RVVDIACGS 56
Query: 410 --KHSVLLLEDGSVWTTGANKYGQL 478
++ L +D +VW+ G YG+L
Sbjct: 57 GDAQTLCLTDDDTVWSWGDGDYGKL 81
Score = 43.2 bits (97), Expect = 7e-04
Identities = 32/115 (27%), Positives = 52/115 (45%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG+ + + P +++ S+AL++ G +Y WG D +LG S+
Sbjct: 80 KLGRGGSDGCKVPMKIDSLTGLGVVKVECGSQFSVALTKSGAVYTWGKGDYHRLG-HGSD 138
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+ ++ P+ V + + IA GS H V EDG V+T G N GQL
Sbjct: 139 DHVRR---PRQVQGLQGKKVIA-----IATGSLHCVCCTEDGEVYTWGDNDEGQL 185
Score = 42.7 bits (96), Expect = 0.001
Identities = 25/96 (26%), Positives = 41/96 (42%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG ++ P QV+ H + +E G++Y WG ND GQLG +
Sbjct: 132 RLGHGSDDHVRRPRQVQGLQGKKVIAIATGSLHCVCCTEDGEVYTWGDNDEGQLG----D 187
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSV 421
+ P+LV ++ +ACGS H++
Sbjct: 188 GTTNAIQRPRLVAALQGK-----KVNRVACGSAHTL 218
>BC042047-1|AAH42047.2| 1022|Homo sapiens hect domain and RLD 6
protein.
Length = 1022
Score = 56.4 bits (130), Expect = 7e-08
Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Frame = +2
Query: 128 RLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKE 307
R QLG+ E P ++ HS+A+ G ++ WG GQLGI E
Sbjct: 52 RGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGE 111
Query: 308 SENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLAC- 484
+ S+ K++ L D ++I ++CG HS+ L +D V++ G N +GQL
Sbjct: 112 FKE--ISFTPKKIMTLND------IKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLG 163
Query: 485 PQYPNSKNFNKV 520
++P+ + +V
Sbjct: 164 KEFPSQASPQRV 175
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/172 (27%), Positives = 71/172 (41%), Gaps = 1/172 (0%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + + + G N Q L LG++ S +P +V HS
Sbjct: 138 YHSLALSKDSQVFSWGKNSHGQ--LGLGKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSF 194
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
ALS G + WG N GQL + ++S P V + L + I+CG H+
Sbjct: 195 ALSLCGTSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKN-----LGVVYISCGDAHT 248
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE-ACRLKCGPWTTV 571
+L +DG V+T G N+ GQL P + V I ++ CG + T+
Sbjct: 249 AVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGLVSQIDCGSYHTL 300
>AY653203-1|AAV66897.1| 322|Homo sapiens truncated HERC6 protein.
Length = 322
Score = 56.4 bits (130), Expect = 7e-08
Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Frame = +2
Query: 128 RLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKE 307
R QLG+ E P ++ HS+A+ G ++ WG GQLGI E
Sbjct: 52 RGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGE 111
Query: 308 SENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLAC- 484
+ S+ K++ L D ++I ++CG HS+ L +D V++ G N +GQL
Sbjct: 112 FKE--ISFTPKKIMTLND------IKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLG 163
Query: 485 PQYPNSKNFNKV 520
++P+ + +V
Sbjct: 164 KEFPSQASPQRV 175
Score = 51.2 bits (117), Expect = 3e-06
Identities = 42/149 (28%), Positives = 62/149 (41%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + + + G N Q L LG++ S +P +V HS
Sbjct: 138 YHSLALSKDSQVFSWGKNSHGQ--LGLGKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSF 194
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
ALS G + WG N GQL + ++S P V + L + I+CG H+
Sbjct: 195 ALSLCGTSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKN-----LGVVYISCGDAHT 248
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSK 505
+L +DG V+T G N+ GQL P +
Sbjct: 249 AVLTQDGKVFTFGDNRSGQLGYSPTPEKR 277
>AY653202-1|AAV66896.1| 364|Homo sapiens truncated HERC6 protein.
Length = 364
Score = 56.4 bits (130), Expect = 7e-08
Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Frame = +2
Query: 128 RLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKE 307
R QLG+ E P ++ HS+A+ G ++ WG GQLGI E
Sbjct: 52 RGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGE 111
Query: 308 SENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLAC- 484
+ S+ K++ L D ++I ++CG HS+ L +D V++ G N +GQL
Sbjct: 112 FKE--ISFTPKKIMTLND------IKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLG 163
Query: 485 PQYPNSKNFNKV 520
++P+ + +V
Sbjct: 164 KEFPSQASPQRV 175
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/172 (27%), Positives = 71/172 (41%), Gaps = 1/172 (0%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + + + G N Q L LG++ S +P +V HS
Sbjct: 138 YHSLALSKDSQVFSWGKNSHGQ--LGLGKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSF 194
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
ALS G + WG N GQL + ++S P V + L + I+CG H+
Sbjct: 195 ALSLCGTSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKN-----LGVVYISCGDAHT 248
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE-ACRLKCGPWTTV 571
+L +DG V+T G N+ GQL P + V I ++ CG + T+
Sbjct: 249 AVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGLVSQIDCGSYHTL 300
>AY653201-1|AAV66895.1| 986|Homo sapiens HERC6 splice variant
protein.
Length = 986
Score = 56.4 bits (130), Expect = 7e-08
Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Frame = +2
Query: 128 RLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKE 307
R QLG+ E P ++ HS+A+ G ++ WG GQLGI E
Sbjct: 52 RGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGE 111
Query: 308 SENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLAC- 484
+ S+ K++ L D ++I ++CG HS+ L +D V++ G N +GQL
Sbjct: 112 FKE--ISFTPKKIMTLND------IKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLG 163
Query: 485 PQYPNSKNFNKV 520
++P+ + +V
Sbjct: 164 KEFPSQASPQRV 175
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/172 (27%), Positives = 71/172 (41%), Gaps = 1/172 (0%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + + + G N Q L LG++ S +P +V HS
Sbjct: 138 YHSLALSKDSQVFSWGKNSHGQ--LGLGKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSF 194
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
ALS G + WG N GQL + ++S P V + L + I+CG H+
Sbjct: 195 ALSLCGTSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKN-----LGVVYISCGDAHT 248
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE-ACRLKCGPWTTV 571
+L +DG V+T G N+ GQL P + V I ++ CG + T+
Sbjct: 249 AVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGLVSQIDCGSYHTL 300
>AF336798-1|AAQ14893.1| 1022|Homo sapiens HERC6 protein.
Length = 1022
Score = 56.4 bits (130), Expect = 7e-08
Identities = 37/132 (28%), Positives = 62/132 (46%), Gaps = 1/132 (0%)
Frame = +2
Query: 128 RLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKE 307
R QLG+ E P ++ HS+A+ G ++ WG GQLGI E
Sbjct: 52 RGQLGRRGAQRGELPEPIQALETLIVDLVSCGKEHSLAVCHKGRVFAWGAGSEGQLGIGE 111
Query: 308 SENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLAC- 484
+ S+ K++ L D ++I ++CG HS+ L +D V++ G N +GQL
Sbjct: 112 FKE--ISFTPKKIMTLND------IKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLG 163
Query: 485 PQYPNSKNFNKV 520
++P+ + +V
Sbjct: 164 KEFPSQASPQRV 175
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/172 (27%), Positives = 71/172 (41%), Gaps = 1/172 (0%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + + + G N Q L LG++ S +P +V HS
Sbjct: 138 YHSLALSKDSQVFSWGKNSHGQ--LGLGKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSF 194
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
ALS G + WG N GQL + ++S P V + L + I+CG H+
Sbjct: 195 ALSLCGTSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKN-----LGVVYISCGDAHT 248
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKE-ACRLKCGPWTTV 571
+L +DG V+T G N+ GQL P + V I ++ CG + T+
Sbjct: 249 AVLTQDGKVFTFGDNRSGQLGYSPTPEKRGPQLVERIDGLVSQIDCGSYHTL 300
>BC038104-1|AAH38104.1| 355|Homo sapiens RCBTB1 protein protein.
Length = 355
Score = 56.0 bits (129), Expect = 1e-07
Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 1/135 (0%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXWHSMALSEFGDLYVWGLNDTGQLGIKES 310
Q+G T+N TP +V SMA+ + G++Y WG N GQLG+ +
Sbjct: 159 QVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNN 218
Query: 311 ENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQ 490
N L + L + + I CG H++ L ++G ++ GAN YGQL
Sbjct: 219 GNQLTPVRVAALHSVC---------VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGN 269
Query: 491 YPNSKNFNKVCVIKE 535
N + + V KE
Sbjct: 270 KNNLLSPAHIMVEKE 284
Score = 51.2 bits (117), Expect = 3e-06
Identities = 34/112 (30%), Positives = 55/112 (49%), Gaps = 3/112 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHL-QIKDIACG 406
HSMAL+ G+++ WG N+ GQ+G + N P+ V +H+ ++ IACG
Sbjct: 139 HSMALAADGEVFAWGYNNCGQVGSGSTANQ----PTPRKV-----TNCLHIKRVVGIACG 189
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEAC--RLKCG 556
S+ +L++G V+ G N GQL N +V + C ++ CG
Sbjct: 190 QTSSMAVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241
Score = 50.0 bits (114), Expect = 6e-06
Identities = 47/174 (27%), Positives = 71/174 (40%), Gaps = 4/174 (2%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXW-HSMAL 244
L T E +V G N N LG D + P ++E H +
Sbjct: 35 LYVTDNDEVFVFGLNYSNC----LGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLS 90
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+E G +Y WG N QLG + + + + +L + Q+ ++ACGS HS+
Sbjct: 91 TEDGVVYAWGHNGYSQLGNGTTNQGIATVQV--CTNL------LIKQVVEVACGSHHSMA 142
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKV--CV-IKEACRLKCGPWTTVVV 577
L DG V+ G N GQ+ N KV C+ IK + CG +++ V
Sbjct: 143 LAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAV 196
Score = 33.5 bits (73), Expect = 0.60
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 4/112 (3%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS- 409
++ +++ +++V+GLN + LG ++++ L +PK ++ + IK ++ GS
Sbjct: 34 ALYVTDNDEVFVFGLNYSNCLGTGDNQSTL----VPKKLEGLCGKK-----IKSLSYGSG 84
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVC---VIKEACRLKCG 556
H +L EDG V+ G N Y QL +VC +IK+ + CG
Sbjct: 85 PHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIATVQVCTNLLIKQVVEVACG 136
>AL139321-5|CAH71047.1| 531|Homo sapiens regulator of chromosome
condensation (RCC1) and BTB (POZ) domain containing pro
protein.
Length = 531
Score = 56.0 bits (129), Expect = 1e-07
Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 1/135 (0%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXWHSMALSEFGDLYVWGLNDTGQLGIKES 310
Q+G T+N TP +V SMA+ + G++Y WG N GQLG+ +
Sbjct: 159 QVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNN 218
Query: 311 ENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQ 490
N L + L + + I CG H++ L ++G ++ GAN YGQL
Sbjct: 219 GNQLTPVRVAALHSVC---------VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGN 269
Query: 491 YPNSKNFNKVCVIKE 535
N + + V KE
Sbjct: 270 KNNLLSPAHIMVEKE 284
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/167 (28%), Positives = 71/167 (42%), Gaps = 4/167 (2%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQV-EXXXXXXXXXXXXXXWHSMAL 244
LL T Y G N ++Q LG T+ P QV HSMAL
Sbjct: 88 LLSTEDGVVYAWGHNGYSQ----LGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMAL 143
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHL-QIKDIACGSKHSV 421
+ G+++ WG N+ GQ+G + N P+ V +H+ ++ IACG S+
Sbjct: 144 AADGEVFAWGYNNCGQVGSGSTANQ----PTPRKV-----TNCLHIKRVVGIACGQTSSM 194
Query: 422 LLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEAC--RLKCG 556
+L++G V+ G N GQL N +V + C ++ CG
Sbjct: 195 AVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241
Score = 49.2 bits (112), Expect = 1e-05
Identities = 47/174 (27%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXW-HSMAL 244
L T E +V G N N LG D + P ++E H +
Sbjct: 35 LYVTDNDEVFVFGLNYSNC----LGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLS 90
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+E G +Y WG N QLG + + + +L + Q+ ++ACGS HS+
Sbjct: 91 TEDGVVYAWGHNGYSQLGNGTTNQGIAPVQV--CTNL------LIKQVVEVACGSHHSMA 142
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKV--CV-IKEACRLKCGPWTTVVV 577
L DG V+ G N GQ+ N KV C+ IK + CG +++ V
Sbjct: 143 LAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAV 196
Score = 32.7 bits (71), Expect = 1.0
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 4/112 (3%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS- 409
++ +++ +++V+GLN + LG ++++ L +PK ++ + IK ++ GS
Sbjct: 34 ALYVTDNDEVFVFGLNYSNCLGTGDNQSTL----VPKKLEGLCGKK-----IKSLSYGSG 84
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVC---VIKEACRLKCG 556
H +L EDG V+ G N Y QL +VC +IK+ + CG
Sbjct: 85 PHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACG 136
>AK096654-1|BAC04833.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39335 fis, clone OCBBF2017398, moderately
similar to Homo sapiens RCC1-like G exchanging factor
RLG mRNA. ).
Length = 531
Score = 56.0 bits (129), Expect = 1e-07
Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 1/135 (0%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXWHSMALSEFGDLYVWGLNDTGQLGIKES 310
Q+G T+N TP +V SMA+ + G++Y WG N GQLG+ +
Sbjct: 159 QVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNN 218
Query: 311 ENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQ 490
N L + L + + I CG H++ L ++G ++ GAN YGQL
Sbjct: 219 GNQLTPVRVAALHSVC---------VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGN 269
Query: 491 YPNSKNFNKVCVIKE 535
N + + V KE
Sbjct: 270 KNNLLSPAHIMVEKE 284
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/167 (28%), Positives = 71/167 (42%), Gaps = 4/167 (2%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQV-EXXXXXXXXXXXXXXWHSMAL 244
LL T Y G N ++Q LG T+ P QV HSMAL
Sbjct: 88 LLSTEDGVVYAWGHNGYSQ----LGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMAL 143
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHL-QIKDIACGSKHSV 421
+ G+++ WG N+ GQ+G + N P+ V +H+ ++ IACG S+
Sbjct: 144 AADGEVFAWGYNNCGQVGSGSTANQ----PTPRKV-----TNCLHIKRVVGIACGQTSSM 194
Query: 422 LLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEAC--RLKCG 556
+L++G V+ G N GQL N +V + C ++ CG
Sbjct: 195 AVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241
Score = 49.2 bits (112), Expect = 1e-05
Identities = 47/174 (27%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXW-HSMAL 244
L T E +V G N N LG D + P ++E H +
Sbjct: 35 LYVTDNDEVFVFGLNYSNC----LGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLS 90
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+E G +Y WG N QLG + + + +L + Q+ ++ACGS HS+
Sbjct: 91 TEDGVVYAWGHNGYSQLGNGTTNQGIAPVQV--CTNL------LIKQVVEVACGSHHSMA 142
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKV--CV-IKEACRLKCGPWTTVVV 577
L DG V+ G N GQ+ N KV C+ IK + CG +++ V
Sbjct: 143 LAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAV 196
Score = 32.7 bits (71), Expect = 1.0
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 4/112 (3%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS- 409
++ +++ +++V+GLN + LG ++++ L +PK ++ + IK ++ GS
Sbjct: 34 ALYVTDNDEVFVFGLNYSNCLGTGDNQSTL----VPKKLEGLCGKK-----IKSLSYGSG 84
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVC---VIKEACRLKCG 556
H +L EDG V+ G N Y QL +VC +IK+ + CG
Sbjct: 85 PHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACG 136
>AJ319660-1|CAC40027.1| 531|Homo sapiens guanine nucleotide
exchange factor protein.
Length = 531
Score = 56.0 bits (129), Expect = 1e-07
Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 1/135 (0%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXWHSMALSEFGDLYVWGLNDTGQLGIKES 310
Q+G T+N TP +V SMA+ + G++Y WG N GQLG+ +
Sbjct: 159 QVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNN 218
Query: 311 ENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQ 490
N L + L + + I CG H++ L ++G ++ GAN YGQL
Sbjct: 219 GNQLTPVRVAALHSVC---------VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGN 269
Query: 491 YPNSKNFNKVCVIKE 535
N + + V KE
Sbjct: 270 KNNLLSPAHIMVEKE 284
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/167 (28%), Positives = 71/167 (42%), Gaps = 4/167 (2%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQV-EXXXXXXXXXXXXXXWHSMAL 244
LL T Y G N ++Q LG T+ P QV HSMAL
Sbjct: 88 LLSTEDGVVYAWGHNGYSQ----LGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMAL 143
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHL-QIKDIACGSKHSV 421
+ G+++ WG N+ GQ+G + N P+ V +H+ ++ IACG S+
Sbjct: 144 AADGEVFAWGYNNCGQVGSGSTANQ----PTPRKV-----TNCLHIKRVVGIACGQTSSM 194
Query: 422 LLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEAC--RLKCG 556
+L++G V+ G N GQL N +V + C ++ CG
Sbjct: 195 AVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241
Score = 49.2 bits (112), Expect = 1e-05
Identities = 47/174 (27%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXW-HSMAL 244
L T E +V G N N LG D + P ++E H +
Sbjct: 35 LYVTDNDEVFVFGLNYSNC----LGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLS 90
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+E G +Y WG N QLG + + + +L + Q+ ++ACGS HS+
Sbjct: 91 TEDGVVYAWGHNGYSQLGNGTTNQGIAPVQV--CTNL------LIKQVVEVACGSHHSMA 142
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKV--CV-IKEACRLKCGPWTTVVV 577
L DG V+ G N GQ+ N KV C+ IK + CG +++ V
Sbjct: 143 LAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAV 196
Score = 32.7 bits (71), Expect = 1.0
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 4/112 (3%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS- 409
++ +++ +++V+GLN + LG ++++ L +PK ++ + IK ++ GS
Sbjct: 34 ALYVTDNDEVFVFGLNYSNCLGTGDNQSTL----VPKKLEGLCGKK-----IKSLSYGSG 84
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVC---VIKEACRLKCG 556
H +L EDG V+ G N Y QL +VC +IK+ + CG
Sbjct: 85 PHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACG 136
>AF334406-1|AAK38372.1| 531|Homo sapiens CLLL7 protein protein.
Length = 531
Score = 56.0 bits (129), Expect = 1e-07
Identities = 39/135 (28%), Positives = 59/135 (43%), Gaps = 1/135 (0%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXWHSMALSEFGDLYVWGLNDTGQLGIKES 310
Q+G T+N TP +V SMA+ + G++Y WG N GQLG+ +
Sbjct: 159 QVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAVLDNGEVYGWGYNGNGQLGLGNN 218
Query: 311 ENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQ 490
N L + L + + I CG H++ L ++G ++ GAN YGQL
Sbjct: 219 GNQLTPVRVAALHSVC---------VNQIVCGYAHTLALTDEGLLYAWGANTYGQLGTGN 269
Query: 491 YPNSKNFNKVCVIKE 535
N + + V KE
Sbjct: 270 KNNLLSPAHIMVEKE 284
Score = 52.0 bits (119), Expect = 2e-06
Identities = 47/167 (28%), Positives = 71/167 (42%), Gaps = 4/167 (2%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQV-EXXXXXXXXXXXXXXWHSMAL 244
LL T Y G N ++Q LG T+ P QV HSMAL
Sbjct: 88 LLSTEDGVVYAWGHNGYSQ----LGNGTTNQGIAPVQVCTNLLIKQVVEVACGSHHSMAL 143
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHL-QIKDIACGSKHSV 421
+ G+++ WG N+ GQ+G + N P+ V +H+ ++ IACG S+
Sbjct: 144 AADGEVFAWGYNNCGQVGSGSTANQ----PTPRKV-----TNCLHIKRVVGIACGQTSSM 194
Query: 422 LLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEAC--RLKCG 556
+L++G V+ G N GQL N +V + C ++ CG
Sbjct: 195 AVLDNGEVYGWGYNGNGQLGLGNNGNQLTPVRVAALHSVCVNQIVCG 241
Score = 49.2 bits (112), Expect = 1e-05
Identities = 47/174 (27%), Positives = 70/174 (40%), Gaps = 4/174 (2%)
Frame = +2
Query: 68 LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXW-HSMAL 244
L T E +V G N N LG D + P ++E H +
Sbjct: 35 LYVTDNDEVFVFGLNYSNC----LGTGDNQSTLVPKKLEGLCGKKIKSLSYGSGPHVLLS 90
Query: 245 SEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVL 424
+E G +Y WG N QLG + + + +L + Q+ ++ACGS HS+
Sbjct: 91 TEDGVVYAWGHNGYSQLGNGTTNQGIAPVQV--CTNL------LIKQVVEVACGSHHSMA 142
Query: 425 LLEDGSVWTTGANKYGQLACPQYPNSKNFNKV--CV-IKEACRLKCGPWTTVVV 577
L DG V+ G N GQ+ N KV C+ IK + CG +++ V
Sbjct: 143 LAADGEVFAWGYNNCGQVGSGSTANQPTPRKVTNCLHIKRVVGIACGQTSSMAV 196
Score = 32.7 bits (71), Expect = 1.0
Identities = 30/112 (26%), Positives = 56/112 (50%), Gaps = 4/112 (3%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS- 409
++ +++ +++V+GLN + LG ++++ L +PK ++ + IK ++ GS
Sbjct: 34 ALYVTDNDEVFVFGLNYSNCLGTGDNQSTL----VPKKLEGLCGKK-----IKSLSYGSG 84
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVC---VIKEACRLKCG 556
H +L EDG V+ G N Y QL +VC +IK+ + CG
Sbjct: 85 PHVLLSTEDGVVYAWGHNGYSQLGNGTTNQGIAPVQVCTNLLIKQVVEVACG 136
>BC142946-1|AAI42947.1| 457|Homo sapiens RCC2 protein protein.
Length = 457
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/83 (38%), Positives = 43/83 (51%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ ++ G L+ WG N+ GQLG D K P+L++ H I ACG
Sbjct: 96 HSLLITTEGKLWSWGRNEKGQLG----HGDTKRVEAPRLIEGLS-----HEVIVSAACGR 146
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H++ L E GSV+ G NK GQL
Sbjct: 147 NHTLALTETGSVFAFGENKMGQL 169
Score = 53.2 bits (122), Expect = 7e-07
Identities = 32/115 (27%), Positives = 57/115 (49%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG DT +E P +E H++AL+E G ++ +G N GQLG+
Sbjct: 116 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT 175
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+ A+P + + + I +ACG++ S+++ G++++ G +YGQL
Sbjct: 176 D-----AVPSPAQIMYNGQ----PITKMACGAEFSMIMDCKGNLYSFGCPEYGQL 221
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 20/169 (11%)
Frame = +2
Query: 32 GCDHCVIV*YLC-----LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXX 196
G H VIV C L T T + G N Q L LG + T + +P Q+
Sbjct: 133 GLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQ--LGLG-NQTDAVPSPAQIMYNGQ 189
Query: 197 XXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLG--------IKESENDLKSYALPKLVD 352
+ SM + G+LY +G + GQLG + + +P+ V
Sbjct: 190 PITKMACGAEF-SMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVA 248
Query: 353 LYDDNEE-------VHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ + + ++ ++D+ACG+ H+++L V++ G YG+L
Sbjct: 249 IFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRL 297
>BC065375-1|AAH65375.1| 458|Homo sapiens secretion regulating
guanine nucleotide exchange factor protein.
Length = 458
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/106 (33%), Positives = 57/106 (53%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS +++ GDL+V GLN GQLG+ +E D+ + K L+ I+ +ACG
Sbjct: 60 HSAVVTDGGDLFVCGLNKDGQLGLGHTE-DIPYFTPCK--SLFG------CPIQQVACGW 110
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRL 547
+++L E+G V + G+N +GQL P P + CV+ +A L
Sbjct: 111 DFTIMLTENGQVLSCGSNSFGQLGVPHGP------RRCVVPQAIEL 150
Score = 43.6 bits (98), Expect = 6e-04
Identities = 27/83 (32%), Positives = 42/83 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS +L++ G++YVWG N GQL N+ +P+ ++ + E ++ I G
Sbjct: 223 HSASLTDAGEVYVWGSNKHGQLA-----NEAAFLPVPQKIEAHCFQNE---KVTAIWSGW 274
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H V E G ++T G YGQL
Sbjct: 275 THLVAQTETGKMFTWGRADYGQL 297
Score = 37.9 bits (84), Expect = 0.028
Identities = 24/73 (32%), Positives = 37/73 (50%)
Frame = +2
Query: 260 LYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDG 439
L+ WG N GQLG+ E+ L LP+ ++ + V + I G HS ++ + G
Sbjct: 17 LFAWGANSYGQLGLGHKEDVL----LPQQLNDFCKPRSV----RRITGGGGHSAVVTDGG 68
Query: 440 SVWTTGANKYGQL 478
++ G NK GQL
Sbjct: 69 DLFVCGLNKDGQL 81
Score = 34.3 bits (75), Expect = 0.34
Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Frame = +2
Query: 77 TTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXW-HSMALSE 250
T E YV GSN Q ++ + L P ++E W H +A +E
Sbjct: 228 TDAGEVYVWGSNKHGQLA-----NEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTE 282
Query: 251 FGDLYVWGLNDTGQLGIK-ESENDLK----SYALP--KLVDLYDDNEEVHLQIKDIACGS 409
G ++ WG D GQLG K E+ K LP + + + +++CGS
Sbjct: 283 TGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEVSCGS 342
Query: 410 KHSVLLLEDGSVWTTGANKYG 472
+H++ ++ G ++ G N++G
Sbjct: 343 EHNLAII-GGVCYSWGWNEHG 362
Score = 33.5 bits (73), Expect = 0.60
Identities = 14/29 (48%), Positives = 19/29 (65%)
Frame = +2
Query: 395 IACGSKHSVLLLEDGSVWTTGANKYGQLA 481
+ GS HS L + G V+ G+NK+GQLA
Sbjct: 217 VLAGSDHSASLTDAGEVYVWGSNKHGQLA 245
>BC053908-1|AAH53908.1| 522|Homo sapiens RCC2 protein protein.
Length = 522
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/83 (38%), Positives = 43/83 (51%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ ++ G L+ WG N+ GQLG D K P+L++ H I ACG
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLG----HGDTKRVEAPRLIEGLS-----HEVIVSAACGR 211
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H++ L E GSV+ G NK GQL
Sbjct: 212 NHTLALTETGSVFAFGENKMGQL 234
Score = 53.2 bits (122), Expect = 7e-07
Identities = 32/115 (27%), Positives = 57/115 (49%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG DT +E P +E H++AL+E G ++ +G N GQLG+
Sbjct: 181 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT 240
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+ A+P + + + I +ACG++ S+++ G++++ G +YGQL
Sbjct: 241 D-----AVPSPAQIMYNGQ----PITKMACGAEFSMIMDCKGNLYSFGCPEYGQL 286
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 20/169 (11%)
Frame = +2
Query: 32 GCDHCVIV*YLC-----LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXX 196
G H VIV C L T T + G N Q L LG + T + +P Q+
Sbjct: 198 GLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQ--LGLG-NQTDAVPSPAQIMYNGQ 254
Query: 197 XXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLG--------IKESENDLKSYALPKLVD 352
+ SM + G+LY +G + GQLG + + +P+ V
Sbjct: 255 PITKMACGAEF-SMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVA 313
Query: 353 LYDDNEE-------VHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ + + ++ ++D+ACG+ H+++L V++ G YG+L
Sbjct: 314 IFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRL 362
>BC042141-1|AAH42141.1| 522|Homo sapiens regulator of chromosome
condensation 2 protein.
Length = 522
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/83 (38%), Positives = 43/83 (51%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ ++ G L+ WG N+ GQLG D K P+L++ H I ACG
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLG----HGDTKRVEAPRLIEGLS-----HEVIVSAACGR 211
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H++ L E GSV+ G NK GQL
Sbjct: 212 NHTLALTETGSVFAFGENKMGQL 234
Score = 53.2 bits (122), Expect = 7e-07
Identities = 32/115 (27%), Positives = 57/115 (49%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG DT +E P +E H++AL+E G ++ +G N GQLG+
Sbjct: 181 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT 240
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+ A+P + + + I +ACG++ S+++ G++++ G +YGQL
Sbjct: 241 D-----AVPSPAQIMYNGQ----PITKMACGAEFSMIMDCKGNLYSFGCPEYGQL 286
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 20/169 (11%)
Frame = +2
Query: 32 GCDHCVIV*YLC-----LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXX 196
G H VIV C L T T + G N Q L LG + T + +P Q+
Sbjct: 198 GLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQ--LGLG-NQTDAVPSPAQIMYNGQ 254
Query: 197 XXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLG--------IKESENDLKSYALPKLVD 352
+ SM + G+LY +G + GQLG + + +P+ V
Sbjct: 255 PITKMACGAEF-SMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVA 313
Query: 353 LYDDNEE-------VHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ + + ++ ++D+ACG+ H+++L V++ G YG+L
Sbjct: 314 IFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRL 362
>AL359612-1|CAB94882.1| 333|Homo sapiens hypothetical protein
protein.
Length = 333
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/83 (38%), Positives = 43/83 (51%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ ++ G L+ WG N+ GQLG D K P+L++ H I ACG
Sbjct: 17 HSLLITTEGKLWSWGRNEKGQLG----HGDTKRVEAPRLIEGLS-----HEVIVSAACGR 67
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H++ L E GSV+ G NK GQL
Sbjct: 68 NHTLALTETGSVFAFGENKMGQL 90
Score = 53.2 bits (122), Expect = 7e-07
Identities = 32/115 (27%), Positives = 57/115 (49%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG DT +E P +E H++AL+E G ++ +G N GQLG+
Sbjct: 37 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT 96
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+ A+P + + + I +ACG++ S+++ G++++ G +YGQL
Sbjct: 97 D-----AVPSPAQIMYNGQ----PITKMACGAEFSMIMDCKGNLYSFGCPEYGQL 142
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 20/169 (11%)
Frame = +2
Query: 32 GCDHCVIV*YLC-----LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXX 196
G H VIV C L T T + G N Q L LG + T + +P Q+
Sbjct: 54 GLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQ--LGLG-NQTDAVPSPAQIMYNGQ 110
Query: 197 XXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLG--------IKESENDLKSYALPKLVD 352
+ SM + G+LY +G + GQLG + + +P+ V
Sbjct: 111 PITKMACGAEF-SMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVA 169
Query: 353 LYDDNEE-------VHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ + + ++ ++D+ACG+ H+++L V++ G YG+L
Sbjct: 170 IFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRL 218
>AJ421269-1|CAD13148.1| 522|Homo sapiens RCC1-like protein protein.
Length = 522
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/83 (38%), Positives = 43/83 (51%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ ++ G L+ WG N+ GQLG D K P+L++ H I ACG
Sbjct: 161 HSLLITTEGKLWSWGRNEKGQLG----HGDTKRVEAPRLIEGLS-----HEVIVSAACGR 211
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H++ L E GSV+ G NK GQL
Sbjct: 212 NHTLALTETGSVFAFGENKMGQL 234
Score = 53.2 bits (122), Expect = 7e-07
Identities = 32/115 (27%), Positives = 57/115 (49%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG DT +E P +E H++AL+E G ++ +G N GQLG+
Sbjct: 181 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT 240
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+ A+P + + + I +ACG++ S+++ G++++ G +YGQL
Sbjct: 241 D-----AVPSPAQIMYNGQ----PITKMACGAEFSMIMDCKGNLYSFGCPEYGQL 286
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 20/169 (11%)
Frame = +2
Query: 32 GCDHCVIV*YLC-----LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXX 196
G H VIV C L T T + G N Q L LG + T + +P Q+
Sbjct: 198 GLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQ--LGLG-NQTDAVPSPAQIMYNGQ 254
Query: 197 XXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLG--------IKESENDLKSYALPKLVD 352
+ SM + G+LY +G + GQLG + + +P+ V
Sbjct: 255 PITKMACGAEF-SMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVA 313
Query: 353 LYDDNEE-------VHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ + + ++ ++D+ACG+ H+++L V++ G YG+L
Sbjct: 314 IFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRL 362
>AJ243951-1|CAB60833.1| 288|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 288
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/106 (33%), Positives = 57/106 (53%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS +++ GDL+V GLN GQLG+ +E D+ + K L+ I+ +ACG
Sbjct: 60 HSAVVTDGGDLFVCGLNKDGQLGLGHTE-DIPYFTPCK--SLFG------CPIQQVACGW 110
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRL 547
+++L E+G V + G+N +GQL P P + CV+ +A L
Sbjct: 111 DFTIMLTENGQVLSCGSNSFGQLGVPHGP------RRCVVPQAIEL 150
Score = 37.9 bits (84), Expect = 0.028
Identities = 24/73 (32%), Positives = 37/73 (50%)
Frame = +2
Query: 260 LYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDG 439
L+ WG N GQLG+ E+ L LP+ ++ + V + I G HS ++ + G
Sbjct: 17 LFAWGANSYGQLGLGHKEDVL----LPQQLNDFCKPRSV----RRITGGGGHSAVVTDGG 68
Query: 440 SVWTTGANKYGQL 478
++ G NK GQL
Sbjct: 69 DLFVCGLNKDGQL 81
Score = 33.5 bits (73), Expect = 0.60
Identities = 14/29 (48%), Positives = 19/29 (65%)
Frame = +2
Query: 395 IACGSKHSVLLLEDGSVWTTGANKYGQLA 481
+ GS HS L + G V+ G+NK+GQLA
Sbjct: 217 VLAGSDHSASLTDAGEVYVWGSNKHGQLA 245
Score = 32.3 bits (70), Expect = 1.4
Identities = 12/22 (54%), Positives = 17/22 (77%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQL 295
HS +L++ G++YVWG N GQL
Sbjct: 223 HSASLTDAGEVYVWGSNKHGQL 244
>AJ243950-1|CAB60832.1| 458|Homo sapiens deafness locus associated
putative guanine nucleotide exchange factor protein.
Length = 458
Score = 55.6 bits (128), Expect = 1e-07
Identities = 36/106 (33%), Positives = 57/106 (53%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS +++ GDL+V GLN GQLG+ +E D+ + K L+ I+ +ACG
Sbjct: 60 HSAVVTDGGDLFVCGLNKDGQLGLGHTE-DIPYFTPCK--SLFG------CPIQQVACGW 110
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRL 547
+++L E+G V + G+N +GQL P P + CV+ +A L
Sbjct: 111 DFTIMLTENGQVLSCGSNSFGQLGVPHGP------RRCVVPQAIEL 150
Score = 43.6 bits (98), Expect = 6e-04
Identities = 27/83 (32%), Positives = 42/83 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS +L++ G++YVWG N GQL N+ +P+ ++ + E ++ I G
Sbjct: 223 HSASLTDAGEVYVWGSNKHGQLA-----NEAAFLPVPQKIEAHCFQNE---KVTAIWSGW 274
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H V E G ++T G YGQL
Sbjct: 275 THLVAQTETGKMFTWGRADYGQL 297
Score = 37.9 bits (84), Expect = 0.028
Identities = 24/73 (32%), Positives = 37/73 (50%)
Frame = +2
Query: 260 LYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDG 439
L+ WG N GQLG+ E+ L LP+ ++ + V + I G HS ++ + G
Sbjct: 17 LFAWGANSYGQLGLGHKEDVL----LPQQLNDFCKPRSV----RRITGGGGHSAVVTDGG 68
Query: 440 SVWTTGANKYGQL 478
++ G NK GQL
Sbjct: 69 DLFVCGLNKDGQL 81
Score = 34.3 bits (75), Expect = 0.34
Identities = 36/141 (25%), Positives = 61/141 (43%), Gaps = 9/141 (6%)
Frame = +2
Query: 77 TTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXX-XXW-HSMALSE 250
T E YV GSN Q ++ + L P ++E W H +A +E
Sbjct: 228 TDAGEVYVWGSNKHGQLA-----NEAAFLPVPQKIEAHCFQNEKVTAIWSGWTHLVAQTE 282
Query: 251 FGDLYVWGLNDTGQLGIK-ESENDLK----SYALP--KLVDLYDDNEEVHLQIKDIACGS 409
G ++ WG D GQLG K E+ K LP + + + +++CGS
Sbjct: 283 TGKMFTWGRADYGQLGRKLETYEGWKLEKQDSFLPCSRPPNSMPSSPHCLTGATEVSCGS 342
Query: 410 KHSVLLLEDGSVWTTGANKYG 472
+H++ ++ G ++ G N++G
Sbjct: 343 EHNLAII-GGVCYSWGWNEHG 362
Score = 33.5 bits (73), Expect = 0.60
Identities = 14/29 (48%), Positives = 19/29 (65%)
Frame = +2
Query: 395 IACGSKHSVLLLEDGSVWTTGANKYGQLA 481
+ GS HS L + G V+ G+NK+GQLA
Sbjct: 217 VLAGSDHSASLTDAGEVYVWGSNKHGQLA 245
>AB040903-1|BAA95994.1| 564|Homo sapiens KIAA1470 protein protein.
Length = 564
Score = 55.6 bits (128), Expect = 1e-07
Identities = 32/83 (38%), Positives = 43/83 (51%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ ++ G L+ WG N+ GQLG D K P+L++ H I ACG
Sbjct: 203 HSLLITTEGKLWSWGRNEKGQLG----HGDTKRVEAPRLIEGLS-----HEVIVSAACGR 253
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H++ L E GSV+ G NK GQL
Sbjct: 254 NHTLALTETGSVFAFGENKMGQL 276
Score = 53.2 bits (122), Expect = 7e-07
Identities = 32/115 (27%), Positives = 57/115 (49%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG DT +E P +E H++AL+E G ++ +G N GQLG+
Sbjct: 223 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT 282
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+ A+P + + + I +ACG++ S+++ G++++ G +YGQL
Sbjct: 283 D-----AVPSPAQIMYNGQ----PITKMACGAEFSMIMDCKGNLYSFGCPEYGQL 328
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 20/169 (11%)
Frame = +2
Query: 32 GCDHCVIV*YLC-----LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXX 196
G H VIV C L T T + G N Q L LG + T + +P Q+
Sbjct: 240 GLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQ--LGLG-NQTDAVPSPAQIMYNGQ 296
Query: 197 XXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLG--------IKESENDLKSYALPKLVD 352
+ SM + G+LY +G + GQLG + + +P+ V
Sbjct: 297 PITKMACGAEF-SMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVA 355
Query: 353 LYDDNEE-------VHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ + + ++ ++D+ACG+ H+++L V++ G YG+L
Sbjct: 356 IFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRL 404
>AY650032-1|AAV66578.1| 117|Homo sapiens HECT and RCC1 containing
protein 4 isoform 2 protein.
Length = 117
Score = 54.4 bits (125), Expect = 3e-07
Identities = 29/93 (31%), Positives = 48/93 (51%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQLG+ + ++ P+ D + ++ +++D+ CG +H+V +L+DG+V+
Sbjct: 4 WGNASFGQLGLGGIDEEI--VLEPRKSDFF-----INKRVRDVGCGLRHTVFVLDDGTVY 56
Query: 449 TTGANKYGQLACPQYPNSKNFNKVCVIKEACRL 547
T G N GQL + KVC I RL
Sbjct: 57 TCGCNDLGQLGHEKSRKKPEILKVCQISRLYRL 89
>AB046813-1|BAB13419.1| 953|Homo sapiens KIAA1593 protein protein.
Length = 953
Score = 54.4 bits (125), Expect = 3e-07
Identities = 46/154 (29%), Positives = 66/154 (42%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + E + G N + Q L LG D +P ++ HS
Sbjct: 43 YHSLALSKASEVFCWGQNKYGQ--LGLGTD-CKKQTSPQLLKSLLGIPFMQVAAGGAHSF 99
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
L+ G ++ WG N GQLG+ + END Y +P L+ + V+ I CG H+
Sbjct: 100 VLTLSGAIFGWGRNKFGQLGLND-END--RY-VPNLLKSLRSQKIVY-----ICCGEDHT 150
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKV 520
L ++G V+T GA YGQL + N KV
Sbjct: 151 AALTKEGGVFTFGAGGYGQLGHNSTSHEINPRKV 184
Score = 36.3 bits (80), Expect = 0.084
Identities = 16/33 (48%), Positives = 21/33 (63%)
Frame = +2
Query: 380 LQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+QI +ACG HS+ L + V+ G NKYGQL
Sbjct: 33 IQIVQVACGYYHSLALSKASEVFCWGQNKYGQL 65
>BC004933-1|AAH04933.1| 351|Homo sapiens RCC2 protein protein.
Length = 351
Score = 53.2 bits (122), Expect = 7e-07
Identities = 32/115 (27%), Positives = 57/115 (49%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG DT +E P +E H++AL+E G ++ +G N GQLG+
Sbjct: 10 QLGHGDTKRVEAPRLIEGLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQLGLGNQT 69
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
+ A+P + + + I +ACG++ S+++ G++++ G +YGQL
Sbjct: 70 D-----AVPSPAQIMYNGQ----PITKMACGAEFSMIMDCKGNLYSFGCPEYGQL 115
Score = 47.2 bits (107), Expect = 5e-05
Identities = 28/70 (40%), Positives = 35/70 (50%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG N+ GQLG D K P+L++ H I ACG H++ L E GSV+
Sbjct: 3 WGRNEKGQLG----HGDTKRVEAPRLIEGLS-----HEVIVSAACGRNHTLALTETGSVF 53
Query: 449 TTGANKYGQL 478
G NK GQL
Sbjct: 54 AFGENKMGQL 63
Score = 35.5 bits (78), Expect = 0.15
Identities = 41/169 (24%), Positives = 71/169 (42%), Gaps = 20/169 (11%)
Frame = +2
Query: 32 GCDHCVIV*YLC-----LLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXX 196
G H VIV C L T T + G N Q L LG + T + +P Q+
Sbjct: 27 GLSHEVIVSAACGRNHTLALTETGSVFAFGENKMGQ--LGLG-NQTDAVPSPAQIMYNGQ 83
Query: 197 XXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLG--------IKESENDLKSYALPKLVD 352
+ SM + G+LY +G + GQLG + + +P+ V
Sbjct: 84 PITKMACGAEF-SMIMDCKGNLYSFGCPEYGQLGHNSDGKFIARAQRIEYDCELVPRRVA 142
Query: 353 LYDDNEE-------VHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
++ + + ++ ++D+ACG+ H+++L V++ G YG+L
Sbjct: 143 IFIEKTKDGQILPVPNVVVRDVACGANHTLVLDSQKRVFSWGFGGYGRL 191
>AL356741-1|CAH74146.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 52.4 bits (120), Expect = 1e-06
Identities = 44/144 (30%), Positives = 63/144 (43%)
Frame = +2
Query: 89 EYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYV 268
E + G N + Q L LG D +P ++ HS L+ G ++
Sbjct: 7 EVFCWGQNKYGQ--LGLGTD-CKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFG 63
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG N GQLG+ + END Y +P L+ + V+ I CG H+ L ++G V+
Sbjct: 64 WGRNKFGQLGLND-END--RY-VPNLLKSLRSQKIVY-----ICCGEDHTAALTKEGGVF 114
Query: 449 TTGANKYGQLACPQYPNSKNFNKV 520
T GA YGQL + N KV
Sbjct: 115 TFGAGGYGQLGHNSTSHEINPRKV 138
>AL133551-1|CAI16031.1| 907|Homo sapiens hect domain and RLD 4
protein.
Length = 907
Score = 52.4 bits (120), Expect = 1e-06
Identities = 44/144 (30%), Positives = 63/144 (43%)
Frame = +2
Query: 89 EYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYV 268
E + G N + Q L LG D +P ++ HS L+ G ++
Sbjct: 7 EVFCWGQNKYGQ--LGLGTD-CKKQTSPQLLKSLLGIPFMQVAAGGAHSFVLTLSGAIFG 63
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG N GQLG+ + END Y +P L+ + V+ I CG H+ L ++G V+
Sbjct: 64 WGRNKFGQLGLND-END--RY-VPNLLKSLRSQKIVY-----ICCGEDHTAALTKEGGVF 114
Query: 449 TTGANKYGQLACPQYPNSKNFNKV 520
T GA YGQL + N KV
Sbjct: 115 TFGAGGYGQLGHNSTSHEINPRKV 138
>X97668-1|CAA66258.1| 815|Homo sapiens XLRP3 protein.
Length = 815
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/167 (25%), Positives = 70/167 (41%)
Frame = +2
Query: 77 TTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFG 256
T + Y+ GSN W QLG S + PT V+ H++ +E G
Sbjct: 51 TGNNKLYMFGSN---NWG-QLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGG 106
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
++Y G N+ GQLG+ ++E + + + +IK ++ GS S L ED
Sbjct: 107 NVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH--------KIKQLSAGSNTSAALTED 158
Query: 437 GSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLKCGPWTTVVV 577
G ++ G N GQ+ N +V + K + CG + + V
Sbjct: 159 GRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFV 205
Score = 50.8 bits (116), Expect = 4e-06
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
Q+G + SN+ P QV +HS ++ G+LYV+G + G+LG+
Sbjct: 171 QIGLKNVSNVCVPQQV--TIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
L ++ P+LV E+ ++ +ACG +H+V+L E+ +V+T G ++GQL
Sbjct: 229 --LGNHRTPQLV------SEIPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQL 274
Score = 46.0 bits (104), Expect = 1e-04
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK 412
S AL+E G L++WG N GQ+G+K N +P+ V + + I+CG
Sbjct: 152 SAALTEDGRLFMWGDNSEGQIGLKNVSN----VCVPQQVT-------IGKPVSWISCGYY 200
Query: 413 HSVLLLEDGSVWTTGANKYGQLACPQ--YPNSKNFNKVCVIKE-ACRLKCGPWTTVVV 577
HS + DG ++ G + G+L P N + V I E ++ CG TVV+
Sbjct: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVL 258
Score = 43.2 bits (97), Expect = 7e-04
Identities = 30/107 (28%), Positives = 47/107 (43%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS ++ LY++G N+ GQLG+ K + L E+V L ACG
Sbjct: 46 HSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKP-----EKVKLA----ACGR 96
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLK 550
H+++ E G+V+ TG N GQL F+ + ++K
Sbjct: 97 NHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIK 143
>U57629-1|AAC50481.1| 815|Homo sapiens retinitis pigmentosa GTPase
regulator protein.
Length = 815
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/167 (25%), Positives = 70/167 (41%)
Frame = +2
Query: 77 TTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFG 256
T + Y+ GSN W QLG S + PT V+ H++ +E G
Sbjct: 51 TGNNKLYMFGSN---NWG-QLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGG 106
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
++Y G N+ GQLG+ ++E + + + +IK ++ GS S L ED
Sbjct: 107 NVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH--------KIKQLSAGSNTSAALTED 158
Query: 437 GSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLKCGPWTTVVV 577
G ++ G N GQ+ N +V + K + CG + + V
Sbjct: 159 GRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFV 205
Score = 50.8 bits (116), Expect = 4e-06
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
Q+G + SN+ P QV +HS ++ G+LYV+G + G+LG+
Sbjct: 171 QIGLKNVSNVCVPQQV--TIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
L ++ P+LV E+ ++ +ACG +H+V+L E+ +V+T G ++GQL
Sbjct: 229 --LGNHRTPQLV------SEIPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQL 274
Score = 46.0 bits (104), Expect = 1e-04
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK 412
S AL+E G L++WG N GQ+G+K N +P+ V + + I+CG
Sbjct: 152 SAALTEDGRLFMWGDNSEGQIGLKNVSN----VCVPQQVT-------IGKPVSWISCGYY 200
Query: 413 HSVLLLEDGSVWTTGANKYGQLACPQ--YPNSKNFNKVCVIKE-ACRLKCGPWTTVVV 577
HS + DG ++ G + G+L P N + V I E ++ CG TVV+
Sbjct: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVL 258
Score = 43.2 bits (97), Expect = 7e-04
Identities = 30/107 (28%), Positives = 47/107 (43%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS ++ LY++G N+ GQLG+ K + L E+V L ACG
Sbjct: 46 HSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKP-----EKVKLA----ACGR 96
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLK 550
H+++ E G+V+ TG N GQL F+ + ++K
Sbjct: 97 NHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIK 143
>BC031624-1|AAH31624.1| 480|Homo sapiens RPGR protein protein.
Length = 480
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/167 (25%), Positives = 70/167 (41%)
Frame = +2
Query: 77 TTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFG 256
T + Y+ GSN W QLG S + PT V+ H++ +E G
Sbjct: 51 TGNNKLYMFGSN---NWG-QLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGG 106
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
++Y G N+ GQLG+ ++E + + + +IK ++ GS S L ED
Sbjct: 107 NVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH--------KIKQLSAGSNTSAALTED 158
Query: 437 GSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLKCGPWTTVVV 577
G ++ G N GQ+ N +V + K + CG + + V
Sbjct: 159 GRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFV 205
Score = 50.8 bits (116), Expect = 4e-06
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
Q+G + SN+ P QV +HS ++ G+LYV+G + G+LG+
Sbjct: 171 QIGLKNVSNVCVPQQV--TIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
L ++ P+LV E+ ++ +ACG +H+V+L E+ +V+T G ++GQL
Sbjct: 229 --LGNHRTPQLV------SEIPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQL 274
Score = 46.0 bits (104), Expect = 1e-04
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK 412
S AL+E G L++WG N GQ+G+K N +P+ V + + I+CG
Sbjct: 152 SAALTEDGRLFMWGDNSEGQIGLKNVSN----VCVPQQVT-------IGKPVSWISCGYY 200
Query: 413 HSVLLLEDGSVWTTGANKYGQLACPQ--YPNSKNFNKVCVIKE-ACRLKCGPWTTVVV 577
HS + DG ++ G + G+L P N + V I E ++ CG TVV+
Sbjct: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVL 258
Score = 43.2 bits (97), Expect = 7e-04
Identities = 30/107 (28%), Positives = 47/107 (43%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS ++ LY++G N+ GQLG+ K + L E+V L ACG
Sbjct: 46 HSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKP-----EKVKLA----ACGR 96
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLK 550
H+++ E G+V+ TG N GQL F+ + ++K
Sbjct: 97 NHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIK 143
>AL606748-2|CAI95407.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/167 (25%), Positives = 70/167 (41%)
Frame = +2
Query: 77 TTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFG 256
T + Y+ GSN W QLG S + PT V+ H++ +E G
Sbjct: 51 TGNNKLYMFGSN---NWG-QLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGG 106
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
++Y G N+ GQLG+ ++E + + + +IK ++ GS S L ED
Sbjct: 107 NVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH--------KIKQLSAGSNTSAALTED 158
Query: 437 GSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLKCGPWTTVVV 577
G ++ G N GQ+ N +V + K + CG + + V
Sbjct: 159 GRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFV 205
Score = 50.8 bits (116), Expect = 4e-06
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
Q+G + SN+ P QV +HS ++ G+LYV+G + G+LG+
Sbjct: 171 QIGLKNVSNVCVPQQV--TIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
L ++ P+LV E+ ++ +ACG +H+V+L E+ +V+T G ++GQL
Sbjct: 229 --LGNHRTPQLV------SEIPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQL 274
Score = 46.0 bits (104), Expect = 1e-04
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK 412
S AL+E G L++WG N GQ+G+K N +P+ V + + I+CG
Sbjct: 152 SAALTEDGRLFMWGDNSEGQIGLKNVSN----VCVPQQVT-------IGKPVSWISCGYY 200
Query: 413 HSVLLLEDGSVWTTGANKYGQLACPQ--YPNSKNFNKVCVIKE-ACRLKCGPWTTVVV 577
HS + DG ++ G + G+L P N + V I E ++ CG TVV+
Sbjct: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVL 258
Score = 43.2 bits (97), Expect = 7e-04
Identities = 30/107 (28%), Positives = 47/107 (43%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS ++ LY++G N+ GQLG+ K + L E+V L ACG
Sbjct: 46 HSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKP-----EKVKLA----ACGR 96
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLK 550
H+++ E G+V+ TG N GQL F+ + ++K
Sbjct: 97 NHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIK 143
>AK223491-1|BAD97211.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator variant protein.
Length = 815
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/167 (25%), Positives = 70/167 (41%)
Frame = +2
Query: 77 TTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFG 256
T + Y+ GSN W QLG S + PT V+ H++ +E G
Sbjct: 51 TGNNKLYMFGSN---NWG-QLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGG 106
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
++Y G N+ GQLG+ ++E + + + +IK ++ GS S L ED
Sbjct: 107 NVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH--------KIKQLSAGSNTSAALTED 158
Query: 437 GSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLKCGPWTTVVV 577
G ++ G N GQ+ N +V + K + CG + + V
Sbjct: 159 GRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFV 205
Score = 50.8 bits (116), Expect = 4e-06
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
Q+G + SN+ P QV +HS ++ G+LYV+G + G+LG+
Sbjct: 171 QIGLKNVSNVCVPQQV--TIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
L ++ P+LV E+ ++ +ACG +H+V+L E+ +V+T G ++GQL
Sbjct: 229 --LGNHRTPQLV------SEIPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQL 274
Score = 46.0 bits (104), Expect = 1e-04
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK 412
S AL+E G L++WG N GQ+G+K N +P+ V + + I+CG
Sbjct: 152 SAALTEDGRLFMWGDNSEGQIGLKNVSN----VCVPQQVT-------IGKPVSWISCGYY 200
Query: 413 HSVLLLEDGSVWTTGANKYGQLACPQ--YPNSKNFNKVCVIKE-ACRLKCGPWTTVVV 577
HS + DG ++ G + G+L P N + V I E ++ CG TVV+
Sbjct: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVL 258
Score = 43.2 bits (97), Expect = 7e-04
Identities = 30/107 (28%), Positives = 47/107 (43%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS ++ LY++G N+ GQLG+ K + L E+V L ACG
Sbjct: 46 HSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKP-----EKVKLA----ACGR 96
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLK 550
H+++ E G+V+ TG N GQL F+ + ++K
Sbjct: 97 NHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIK 143
>AJ238395-1|CAB54002.1| 646|Homo sapiens RPGR protein protein.
Length = 646
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/167 (25%), Positives = 70/167 (41%)
Frame = +2
Query: 77 TTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFG 256
T + Y+ GSN W QLG S + PT V+ H++ +E G
Sbjct: 51 TGNNKLYMFGSN---NWG-QLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGG 106
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
++Y G N+ GQLG+ ++E + + + +IK ++ GS S L ED
Sbjct: 107 NVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH--------KIKQLSAGSNTSAALTED 158
Query: 437 GSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLKCGPWTTVVV 577
G ++ G N GQ+ N +V + K + CG + + V
Sbjct: 159 GRLFMWGDNSEGQIGLKNVSNVCVPQQVTIGKPVSWISCGYYHSAFV 205
Score = 50.8 bits (116), Expect = 4e-06
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
Q+G + SN+ P QV +HS ++ G+LYV+G + G+LG+
Sbjct: 171 QIGLKNVSNVCVPQQV--TIGKPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
L ++ P+LV E+ ++ +ACG +H+V+L E+ +V+T G ++GQL
Sbjct: 229 --LGNHRTPQLV------SEIPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQL 274
Score = 46.0 bits (104), Expect = 1e-04
Identities = 36/118 (30%), Positives = 55/118 (46%), Gaps = 3/118 (2%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK 412
S AL+E G L++WG N GQ+G+K N +P+ V + + I+CG
Sbjct: 152 SAALTEDGRLFMWGDNSEGQIGLKNVSN----VCVPQQVT-------IGKPVSWISCGYY 200
Query: 413 HSVLLLEDGSVWTTGANKYGQLACPQ--YPNSKNFNKVCVIKE-ACRLKCGPWTTVVV 577
HS + DG ++ G + G+L P N + V I E ++ CG TVV+
Sbjct: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVL 258
Score = 43.2 bits (97), Expect = 7e-04
Identities = 30/107 (28%), Positives = 47/107 (43%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS ++ LY++G N+ GQLG+ K + L E+V L ACG
Sbjct: 46 HSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKP-----EKVKLA----ACGR 96
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLK 550
H+++ E G+V+ TG N GQL F+ + ++K
Sbjct: 97 NHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIK 143
>AK092403-1|BAC03879.1| 184|Homo sapiens protein ( Homo sapiens
cDNA FLJ35084 fis, clone PLACE6005482. ).
Length = 184
Score = 51.2 bits (117), Expect = 3e-06
Identities = 42/149 (28%), Positives = 62/149 (41%)
Frame = +2
Query: 59 YLCLLFTTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSM 238
Y L + + + G N Q L LG++ S +P +V HS
Sbjct: 16 YHSLALSKDSQVFSWGKNSHGQ--LGLGKEFPSQA-SPQRVRSLEGIPLAQVAAGGAHSF 72
Query: 239 ALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHS 418
ALS G + WG N GQL + ++S P V + L + I+CG H+
Sbjct: 73 ALSLCGTSFGWGSNSAGQLALSGRNVPVQSNK-PLSVGALKN-----LGVVYISCGDAHT 126
Query: 419 VLLLEDGSVWTTGANKYGQLACPQYPNSK 505
+L +DG V+T G N+ GQL P +
Sbjct: 127 AVLTQDGKVFTFGDNRSGQLGYSPTPEKR 155
Score = 34.3 bits (75), Expect = 0.34
Identities = 15/48 (31%), Positives = 29/48 (60%), Gaps = 1/48 (2%)
Frame = +2
Query: 380 LQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLAC-PQYPNSKNFNKV 520
++I ++CG HS+ L +D V++ G N +GQL ++P+ + +V
Sbjct: 6 IKIIQVSCGHYHSLALSKDSQVFSWGKNSHGQLGLGKEFPSQASPQRV 53
>AF224249-1|AAO27475.1| 328|Homo sapiens HERC2 protein.
Length = 328
Score = 51.2 bits (117), Expect = 3e-06
Identities = 33/117 (28%), Positives = 57/117 (48%), Gaps = 2/117 (1%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG N + P +E HS AL+ G+LY WGL + G+LG ++
Sbjct: 116 KLGHFSRMNCDKPRLIEALKTKRIRDIACGSSHSAALTSSGELYTWGLGEYGRLGHGDNT 175
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK--HSVLLLEDGSVWTTGANKYGQL 478
LK PK+V + + ++ +ACGS+ ++ L ++G V++ G +G+L
Sbjct: 176 TQLK----PKMVKVL-----LGHRVIQVACGSRDAQTLALTDEGLVFSWGDGDFGKL 223
Score = 36.3 bits (80), Expect = 0.084
Identities = 24/82 (29%), Positives = 42/82 (51%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK 412
++AL++ G ++ WG D G+LG SE +P+ ++ + + I CG++
Sbjct: 203 TLALTDEGLVFSWGDGDFGKLGRGGSEG----CNIPQNIERLNGQG-----VCQIECGAQ 253
Query: 413 HSVLLLEDGSVWTTGANKYGQL 478
S+ L + G VWT G Y +L
Sbjct: 254 FSLALTKSGVVWTWGKGDYFRL 275
>AJ318463-1|CAC86116.1| 815|Homo sapiens retinitis pigmentosa
GTPase regulator protein.
Length = 815
Score = 50.8 bits (116), Expect = 4e-06
Identities = 35/115 (30%), Positives = 61/115 (53%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
Q+G + SN+ P QV +HS ++ G+LYV+G + G+LG+
Sbjct: 171 QIGLKNVSNVCVPQQV--TIGNPVSWISCGYYHSAFVTTDGELYVFGEPENGKLGLPNQL 228
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
L ++ P+LV E+ ++ +ACG +H+V+L E+ +V+T G ++GQL
Sbjct: 229 --LGNHRTPQLV------SEIPEKVIQVACGGEHTVVLTEN-AVYTFGLGQFGQL 274
Score = 50.0 bits (114), Expect = 6e-06
Identities = 42/150 (28%), Positives = 65/150 (43%)
Frame = +2
Query: 77 TTTMEYYVAGSNLFNQWRLQLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFG 256
T + Y+ GSN W QLG S + PT V+ H++ +E G
Sbjct: 51 TGNNKLYMFGSN---NWG-QLGLGSKSAISKPTCVKALKPEKVKLAACGRNHTLVSTEGG 106
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
++Y G N+ GQLG+ ++E + + + +IK ++ GS S L ED
Sbjct: 107 NVYATGGNNEGQLGLGDTEERNTFHVISFFTSEH--------KIKQLSAGSNTSAALTED 158
Query: 437 GSVWTTGANKYGQLACPQYPNSKNFNKVCV 526
G ++ G N GQ+ KN + VCV
Sbjct: 159 GRLFMWGDNSEGQIGL------KNVSNVCV 182
Score = 46.4 bits (105), Expect = 8e-05
Identities = 36/118 (30%), Positives = 56/118 (47%), Gaps = 3/118 (2%)
Frame = +2
Query: 233 SMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSK 412
S AL+E G L++WG N GQ+G+K N +P+ V + + + I+CG
Sbjct: 152 SAALTEDGRLFMWGDNSEGQIGLKNVSN----VCVPQQVTIGN-------PVSWISCGYY 200
Query: 413 HSVLLLEDGSVWTTGANKYGQLACPQ--YPNSKNFNKVCVIKE-ACRLKCGPWTTVVV 577
HS + DG ++ G + G+L P N + V I E ++ CG TVV+
Sbjct: 201 HSAFVTTDGELYVFGEPENGKLGLPNQLLGNHRTPQLVSEIPEKVIQVACGGEHTVVL 258
Score = 43.2 bits (97), Expect = 7e-04
Identities = 30/107 (28%), Positives = 47/107 (43%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS ++ LY++G N+ GQLG+ K + L E+V L ACG
Sbjct: 46 HSAVVTGNNKLYMFGSNNWGQLGLGSKSAISKPTCVKALKP-----EKVKLA----ACGR 96
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLK 550
H+++ E G+V+ TG N GQL F+ + ++K
Sbjct: 97 NHTLVSTEGGNVYATGGNNEGQLGLGDTEERNTFHVISFFTSEHKIK 143
>AL359257-2|CAI39759.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 49.6 bits (113), Expect = 8e-06
Identities = 37/118 (31%), Positives = 48/118 (40%), Gaps = 2/118 (1%)
Frame = +2
Query: 140 GQDDTSNLET--PTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
G+ D S + T P V HS+ L E GD+Y +G GQLG
Sbjct: 881 GEKDASKITTYPPGSVRFDCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLG----H 936
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
D+ S P LV + GS H+ +LL DG V+T G+ GQL P
Sbjct: 937 GDVNSRGCPTLVQALPGPST------QVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRP 988
Score = 34.3 bits (75), Expect = 0.34
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = +2
Query: 386 IKDIACGSKHSVLLLEDGSVWTTGANKYGQ 475
+ +A G H+ +L+++G VWT G N GQ
Sbjct: 645 VTQVAMGKAHTCVLMKNGEVWTFGVNNKGQ 674
>AL159158-1|CAI16842.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 49.6 bits (113), Expect = 8e-06
Identities = 37/118 (31%), Positives = 48/118 (40%), Gaps = 2/118 (1%)
Frame = +2
Query: 140 GQDDTSNLET--PTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
G+ D S + T P V HS+ L E GD+Y +G GQLG
Sbjct: 881 GEKDASKITTYPPGSVRFDCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLG----H 936
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
D+ S P LV + GS H+ +LL DG V+T G+ GQL P
Sbjct: 937 GDVNSRGCPTLVQALPGPST------QVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRP 988
Score = 34.3 bits (75), Expect = 0.34
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = +2
Query: 386 IKDIACGSKHSVLLLEDGSVWTTGANKYGQ 475
+ +A G H+ +L+++G VWT G N GQ
Sbjct: 645 VTQVAMGKAHTCVLMKNGEVWTFGVNNKGQ 674
>AL159154-1|CAH73736.1| 4640|Homo sapiens AC001226.5 protein.
Length = 4640
Score = 49.6 bits (113), Expect = 8e-06
Identities = 37/118 (31%), Positives = 48/118 (40%), Gaps = 2/118 (1%)
Frame = +2
Query: 140 GQDDTSNLET--PTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
G+ D S + T P V HS+ L E GD+Y +G GQLG
Sbjct: 881 GEKDASKITTYPPGSVRFDCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLG----H 936
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
D+ S P LV + GS H+ +LL DG V+T G+ GQL P
Sbjct: 937 GDVNSRGCPTLVQALPGPST------QVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRP 988
Score = 34.3 bits (75), Expect = 0.34
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = +2
Query: 386 IKDIACGSKHSVLLLEDGSVWTTGANKYGQ 475
+ +A G H+ +L+++G VWT G N GQ
Sbjct: 645 VTQVAMGKAHTCVLMKNGEVWTFGVNNKGQ 674
>AF075587-1|AAC39928.1| 4641|Homo sapiens protein associated with Myc
protein.
Length = 4641
Score = 49.6 bits (113), Expect = 8e-06
Identities = 37/118 (31%), Positives = 48/118 (40%), Gaps = 2/118 (1%)
Frame = +2
Query: 140 GQDDTSNLET--PTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
G+ D S + T P V HS+ L E GD+Y +G GQLG
Sbjct: 881 GEKDASKITTYPPGSVRFDCELRAVQVSCGFHHSVVLMENGDVYTFGYGQHGQLG----H 936
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
D+ S P LV + GS H+ +LL DG V+T G+ GQL P
Sbjct: 937 GDVNSRGCPTLVQALPGPST------QVTAGSNHTAVLLMDGQVFTFGSFSKGQLGRP 988
Score = 34.3 bits (75), Expect = 0.34
Identities = 12/30 (40%), Positives = 19/30 (63%)
Frame = +2
Query: 386 IKDIACGSKHSVLLLEDGSVWTTGANKYGQ 475
+ +A G H+ +L+++G VWT G N GQ
Sbjct: 645 VTQVAMGKAHTCVLMKNGEVWTFGVNNKGQ 674
>AY650034-1|AAV66580.1| 110|Homo sapiens HECT and RCC1 containing
protein 4 isoform 4 protein.
Length = 110
Score = 48.4 bits (110), Expect = 2e-05
Identities = 23/70 (32%), Positives = 41/70 (58%)
Frame = +2
Query: 269 WGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVW 448
WG GQLG+ + ++ P+ D + ++ +++D+ CG +H+V +L+DG+V+
Sbjct: 4 WGNASFGQLGLGGIDEEI--VLEPRKSDFF-----INKRVRDVGCGLRHTVFVLDDGTVY 56
Query: 449 TTGANKYGQL 478
T G N GQL
Sbjct: 57 TCGCNDLGQL 66
>BC113705-1|AAI13706.1| 692|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 8 protein.
Length = 692
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/114 (26%), Positives = 51/114 (44%)
Frame = +2
Query: 137 LGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESEN 316
LG +++ PT VE H +ALS +L+ WG D+G+LG+ E
Sbjct: 423 LGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRE- 481
Query: 317 DLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
S++ P+ V + E + + CG S++L G G+N++ +L
Sbjct: 482 ---SHSCPQQVPMPPGQE-----AQRVVCGIDSSMILTVPGQALACGSNRFNKL 527
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS A++ GD Y +G N GQLG N + P V + +++ +ACG
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLG----TNTRRGSRAPCKVQGLEG-----IKMAMVACGD 622
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
+V + + V++ G G+L
Sbjct: 623 AFTVAIGAESEVYSWGKGARGRL 645
>BC112240-1|AAI12241.1| 692|Homo sapiens NIMA-related kinase 8
protein.
Length = 692
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/114 (26%), Positives = 51/114 (44%)
Frame = +2
Query: 137 LGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESEN 316
LG +++ PT VE H +ALS +L+ WG D+G+LG+ E
Sbjct: 423 LGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRE- 481
Query: 317 DLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
S++ P+ V + E + + CG S++L G G+N++ +L
Sbjct: 482 ---SHSCPQQVPMPPGQE-----AQRVVCGIDSSMILTVPGQALACGSNRFNKL 527
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS A++ GD Y +G N GQLG N + P V + +++ +ACG
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLG----TNTRRGSRAPCKVQGLEG-----IKMAMVACGD 622
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
+V + + V++ G G+L
Sbjct: 623 AFTVAIGAESEVYSWGKGARGRL 645
>AY267371-1|AAP04006.1| 692|Homo sapiens NIMA-family kinase NEK8
protein.
Length = 692
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/114 (26%), Positives = 51/114 (44%)
Frame = +2
Query: 137 LGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESEN 316
LG +++ PT VE H +ALS +L+ WG D+G+LG+ E
Sbjct: 423 LGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRE- 481
Query: 317 DLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
S++ P+ V + E + + CG S++L G G+N++ +L
Sbjct: 482 ---SHSCPQQVPMPPGQE-----AQRVVCGIDSSMILTVPGQALACGSNRFNKL 527
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS A++ GD Y +G N GQLG N + P V + +++ +ACG
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLG----TNTRRGSRAPCKVQGLEG-----IKMAMVACGD 622
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
+V + + V++ G G+L
Sbjct: 623 AFTVAIGAESEVYSWGKGARGRL 645
>AY242354-1|AAO88243.1| 692|Homo sapiens NIMA-related kinase 12a
protein.
Length = 692
Score = 46.4 bits (105), Expect = 8e-05
Identities = 30/114 (26%), Positives = 51/114 (44%)
Frame = +2
Query: 137 LGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESEN 316
LG +++ PT VE H +ALS +L+ WG D+G+LG+ E
Sbjct: 423 LGHGSLTDISQPTIVEALLGYEMVQVACGASHVLALSTERELFAWGRGDSGRLGLGTRE- 481
Query: 317 DLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
S++ P+ V + E + + CG S++L G G+N++ +L
Sbjct: 482 ---SHSCPQQVPMPPGQE-----AQRVVCGIDSSMILTVPGQALACGSNRFNKL 527
Score = 31.9 bits (69), Expect = 1.8
Identities = 23/83 (27%), Positives = 38/83 (45%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS A++ GD Y +G N GQLG N + P V + +++ +ACG
Sbjct: 572 HSAAVTASGDCYTFGSNQHGQLG----TNTRRGSRAPCKVQGLEG-----IKMAMVACGD 622
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
+V + + V++ G G+L
Sbjct: 623 AFTVAIGAESEVYSWGKGARGRL 645
>X12654-1|CAA31182.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLG-IKE------SENDLKSYALPKLVDLYDDNEEVHLQI 388
H + L+ GDLY G + GQLG + E L+ +PK V L H++
Sbjct: 183 HLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRF 242
Query: 389 KDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
+D CG+ + + +G V+ G + Y QL P
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP 275
Score = 39.5 bits (88), Expect = 0.009
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGL--NDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIAC 403
H+ AL++ G +++WG ++ G +G+ E +K +P V L + + +A
Sbjct: 130 HTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQL-------DVPVVKVAS 179
Query: 404 GSKHSVLLLEDGSVWTTGANKYGQL 478
G+ H V+L DG ++T G + GQL
Sbjct: 180 GNDHLVMLTADGDLYTLGCGEQGQL 204
Score = 33.5 bits (73), Expect = 0.60
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +E G + G D GQLG+ E+ + K P LV + +D + G
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK---PALVSIPED-------VVQAEAGG 76
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H+V L + G V++ G N G L
Sbjct: 77 MHTVCLSKSGQVYSFGCNDEGAL 99
Score = 29.9 bits (64), Expect = 7.3
Identities = 21/94 (22%), Positives = 46/94 (48%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+ + A+S G +Y +GL++ QLG +E S +P+ + + ++ + + G
Sbjct: 250 YFTFAISHEGHVYGFGLSNYHQLGTPGTE----SCFIPQNLTSFKNSTKSWVGFSG---G 302
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V + +G ++ G +YG+L + K+
Sbjct: 303 QHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS 336
>X06130-1|CAA29496.1| 421|Homo sapiens protein ( Human mRNA for
cell cycle gene RCC1. ).
Length = 421
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLG-IKE------SENDLKSYALPKLVDLYDDNEEVHLQI 388
H + L+ GDLY G + GQLG + E L+ +PK V L H++
Sbjct: 183 HLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRF 242
Query: 389 KDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
+D CG+ + + +G V+ G + Y QL P
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP 275
Score = 39.5 bits (88), Expect = 0.009
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGL--NDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIAC 403
H+ AL++ G +++WG ++ G +G+ E +K +P V L + + +A
Sbjct: 130 HTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQL-------DVPVVKVAS 179
Query: 404 GSKHSVLLLEDGSVWTTGANKYGQL 478
G+ H V+L DG ++T G + GQL
Sbjct: 180 GNDHLVMLTADGDLYTLGCGEQGQL 204
Score = 33.5 bits (73), Expect = 0.60
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +E G + G D GQLG+ E+ + K P LV + +D + G
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK---PALVSIPED-------VVQAEAGG 76
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H+V L + G V++ G N G L
Sbjct: 77 MHTVCLSKSGQVYSFGCNDEGAL 99
Score = 29.9 bits (64), Expect = 7.3
Identities = 21/94 (22%), Positives = 46/94 (48%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+ + A+S G +Y +GL++ QLG +E S +P+ + + ++ + + G
Sbjct: 250 YFTFAISHEGHVYGFGLSNYHQLGTPGTE----SCFIPQNLTSFKNSTKSWVGFSG---G 302
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V + +G ++ G +YG+L + K+
Sbjct: 303 QHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS 336
>D00591-1|BAA00469.1| 421|Homo sapiens RCC1 protein.
Length = 421
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLG-IKE------SENDLKSYALPKLVDLYDDNEEVHLQI 388
H + L+ GDLY G + GQLG + E L+ +PK V L H++
Sbjct: 183 HLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRF 242
Query: 389 KDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
+D CG+ + + +G V+ G + Y QL P
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP 275
Score = 39.5 bits (88), Expect = 0.009
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGL--NDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIAC 403
H+ AL++ G +++WG ++ G +G+ E +K +P V L + + +A
Sbjct: 130 HTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQL-------DVPVVKVAS 179
Query: 404 GSKHSVLLLEDGSVWTTGANKYGQL 478
G+ H V+L DG ++T G + GQL
Sbjct: 180 GNDHLVMLTADGDLYTLGCGEQGQL 204
Score = 33.5 bits (73), Expect = 0.60
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +E G + G D GQLG+ E+ + K P LV + +D + G
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK---PALVSIPED-------VVQAEAGG 76
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H+V L + G V++ G N G L
Sbjct: 77 MHTVCLSKSGQVYSFGCNDEGAL 99
Score = 29.9 bits (64), Expect = 7.3
Identities = 21/94 (22%), Positives = 46/94 (48%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+ + A+S G +Y +GL++ QLG +E S +P+ + + ++ + + G
Sbjct: 250 YFTFAISHEGHVYGFGLSNYHQLGTPGTE----SCFIPQNLTSFKNSTKSWVGFSG---G 302
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V + +G ++ G +YG+L + K+
Sbjct: 303 QHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS 336
>DQ005634-1|AAY55907.1| 1196|Homo sapiens inhibitor of Bruton's
tyrosine kinase-beta protein.
Length = 1196
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/94 (31%), Positives = 48/94 (51%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+HS+ LS+ G +Y G G+LG D ++ +P+LV+ + + +A
Sbjct: 187 FHSVFLSQKGQVYTCGHGPGGRLG----HGDEQTCLVPRLVEGLNGHN-----CSQVAAA 237
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V+L EDG V+T G N + QL P+S N
Sbjct: 238 KDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCN 271
Score = 37.5 bits (83), Expect = 0.037
Identities = 36/124 (29%), Positives = 52/124 (41%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D P VE H++ L+E G +Y +GLN QLGI
Sbjct: 208 RLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPP 267
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQY 493
+ S +P+ + I +A G H+VL + +V+T G N GQL C
Sbjct: 268 S---SCNVPRQIQAKYLKGRT---IIGVAAGRFHTVLWTRE-AVYTMGLNG-GQLGCLLD 319
Query: 494 PNSK 505
PN +
Sbjct: 320 PNGE 323
>DQ005633-1|AAY55906.1| 1353|Homo sapiens inhibitor of Bruton's
tyrosine kinase-alpha protein.
Length = 1353
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/94 (31%), Positives = 48/94 (51%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+HS+ LS+ G +Y G G+LG D ++ +P+LV+ + + +A
Sbjct: 187 FHSVFLSQKGQVYTCGHGPGGRLG----HGDEQTCLVPRLVEGLNGHN-----CSQVAAA 237
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V+L EDG V+T G N + QL P+S N
Sbjct: 238 KDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCN 271
Score = 37.5 bits (83), Expect = 0.037
Identities = 36/124 (29%), Positives = 52/124 (41%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D P VE H++ L+E G +Y +GLN QLGI
Sbjct: 208 RLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPP 267
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQY 493
+ S +P+ + I +A G H+VL + +V+T G N GQL C
Sbjct: 268 S---SCNVPRQIQAKYLKGRT---IIGVAAGRFHTVLWTRE-AVYTMGLNG-GQLGCLLD 319
Query: 494 PNSK 505
PN +
Sbjct: 320 PNGE 323
>CR407693-1|CAG28621.1| 421|Homo sapiens CHC1 protein.
Length = 421
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLG-IKE------SENDLKSYALPKLVDLYDDNEEVHLQI 388
H + L+ GDLY G + GQLG + E L+ +PK V L H++
Sbjct: 183 HLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRF 242
Query: 389 KDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
+D CG+ + + +G V+ G + Y QL P
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP 275
Score = 39.5 bits (88), Expect = 0.009
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGL--NDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIAC 403
H+ AL++ G +++WG ++ G +G+ E +K +P V L + + +A
Sbjct: 130 HTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQL-------DVPVVKVAS 179
Query: 404 GSKHSVLLLEDGSVWTTGANKYGQL 478
G+ H V+L DG ++T G + GQL
Sbjct: 180 GNDHLVMLTADGDLYTLGCGEQGQL 204
Score = 33.5 bits (73), Expect = 0.60
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +E G + G D GQLG+ E+ + K P LV + +D + G
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK---PALVSIPED-------VVQAEAGG 76
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H+V L + G V++ G N G L
Sbjct: 77 MHTVCLSKSGQVYSFGCNDEGAL 99
Score = 29.9 bits (64), Expect = 7.3
Identities = 21/94 (22%), Positives = 46/94 (48%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+ + A+S G +Y +GL++ QLG +E S +P+ + + ++ + + G
Sbjct: 250 YFTFAISHEGHVYGFGLSNYHQLGTPGTE----SCFIPQNLTSFKNSTKSWVGFSG---G 302
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V + +G ++ G +YG+L + K+
Sbjct: 303 QHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS 336
>BC113698-1|AAI13699.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/94 (31%), Positives = 48/94 (51%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+HS+ LS+ G +Y G G+LG D ++ +P+LV+ + + +A
Sbjct: 187 FHSVFLSQKGQVYTCGHGPGGRLG----HGDEQTCLVPRLVEGLNGHN-----CSQVAAA 237
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V+L EDG V+T G N + QL P+S N
Sbjct: 238 KDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCN 271
Score = 37.5 bits (83), Expect = 0.037
Identities = 36/124 (29%), Positives = 52/124 (41%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D P VE H++ L+E G +Y +GLN QLGI
Sbjct: 208 RLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPP 267
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQY 493
+ S +P+ + I +A G H+VL + +V+T G N GQL C
Sbjct: 268 S---SCNVPRQIQAKYLKGRT---IIGVAAGRFHTVLWTRE-AVYTMGLNG-GQLGCLLD 319
Query: 494 PNSK 505
PN +
Sbjct: 320 PNGE 323
>BC113696-1|AAI13697.1| 1353|Homo sapiens inhibitor of Bruton
agammaglobulinemia tyrosine kinase protein.
Length = 1353
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/94 (31%), Positives = 48/94 (51%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+HS+ LS+ G +Y G G+LG D ++ +P+LV+ + + +A
Sbjct: 187 FHSVFLSQKGQVYTCGHGPGGRLG----HGDEQTCLVPRLVEGLNGHN-----CSQVAAA 237
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V+L EDG V+T G N + QL P+S N
Sbjct: 238 KDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCN 271
Score = 37.5 bits (83), Expect = 0.037
Identities = 36/124 (29%), Positives = 52/124 (41%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D P VE H++ L+E G +Y +GLN QLGI
Sbjct: 208 RLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPP 267
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQY 493
+ S +P+ + I +A G H+VL + +V+T G N GQL C
Sbjct: 268 S---SCNVPRQIQAKYLKGRT---IIGVAAGRFHTVLWTRE-AVYTMGLNG-GQLGCLLD 319
Query: 494 PNSK 505
PN +
Sbjct: 320 PNGE 323
>BC069198-1|AAH69198.1| 452|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 452
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLG-IKE------SENDLKSYALPKLVDLYDDNEEVHLQI 388
H + L+ GDLY G + GQLG + E L+ +PK V L H++
Sbjct: 214 HLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRF 273
Query: 389 KDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
+D CG+ + + +G V+ G + Y QL P
Sbjct: 274 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP 306
Score = 39.5 bits (88), Expect = 0.009
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGL--NDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIAC 403
H+ AL++ G +++WG ++ G +G+ E +K +P V L + + +A
Sbjct: 161 HTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQL-------DVPVVKVAS 210
Query: 404 GSKHSVLLLEDGSVWTTGANKYGQL 478
G+ H V+L DG ++T G + GQL
Sbjct: 211 GNDHLVMLTADGDLYTLGCGEQGQL 235
Score = 33.5 bits (73), Expect = 0.60
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +E G + G D GQLG+ E+ + K P LV + +D + G
Sbjct: 58 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK---PALVSIPED-------VVQAEAGG 107
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H+V L + G V++ G N G L
Sbjct: 108 MHTVCLSKSGQVYSFGCNDEGAL 130
Score = 29.9 bits (64), Expect = 7.3
Identities = 21/94 (22%), Positives = 46/94 (48%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+ + A+S G +Y +GL++ QLG +E S +P+ + + ++ + + G
Sbjct: 281 YFTFAISHEGHVYGFGLSNYHQLGTPGTE----SCFIPQNLTSFKNSTKSWVGFSG---G 333
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V + +G ++ G +YG+L + K+
Sbjct: 334 QHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS 367
>BC036903-1|AAH36903.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLG-IKE------SENDLKSYALPKLVDLYDDNEEVHLQI 388
H + L+ GDLY G + GQLG + E L+ +PK V L H++
Sbjct: 183 HLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRF 242
Query: 389 KDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
+D CG+ + + +G V+ G + Y QL P
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP 275
Score = 39.5 bits (88), Expect = 0.009
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGL--NDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIAC 403
H+ AL++ G +++WG ++ G +G+ E +K +P V L + + +A
Sbjct: 130 HTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQL-------DVPVVKVAS 179
Query: 404 GSKHSVLLLEDGSVWTTGANKYGQL 478
G+ H V+L DG ++T G + GQL
Sbjct: 180 GNDHLVMLTADGDLYTLGCGEQGQL 204
Score = 33.5 bits (73), Expect = 0.60
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +E G + G D GQLG+ E+ + K P LV + +D + G
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK---PALVSIPED-------VVQAEAGG 76
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H+V L + G V++ G N G L
Sbjct: 77 MHTVCLSKSGQVYSFGCNDEGAL 99
Score = 29.9 bits (64), Expect = 7.3
Identities = 21/94 (22%), Positives = 46/94 (48%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+ + A+S G +Y +GL++ QLG +E S +P+ + + ++ + + G
Sbjct: 250 YFTFAISHEGHVYGFGLSNYHQLGTPGTE----SCFIPQNLTSFKNSTKSWVGFSG---G 302
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V + +G ++ G +YG+L + K+
Sbjct: 303 QHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS 336
>BC010067-1|AAH10067.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLG-IKE------SENDLKSYALPKLVDLYDDNEEVHLQI 388
H + L+ GDLY G + GQLG + E L+ +PK V L H++
Sbjct: 183 HLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRF 242
Query: 389 KDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
+D CG+ + + +G V+ G + Y QL P
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP 275
Score = 39.5 bits (88), Expect = 0.009
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGL--NDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIAC 403
H+ AL++ G +++WG ++ G +G+ E +K +P V L + + +A
Sbjct: 130 HTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQL-------DVPVVKVAS 179
Query: 404 GSKHSVLLLEDGSVWTTGANKYGQL 478
G+ H V+L DG ++T G + GQL
Sbjct: 180 GNDHLVMLTADGDLYTLGCGEQGQL 204
Score = 33.5 bits (73), Expect = 0.60
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +E G + G D GQLG+ E+ + K P LV + +D + G
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK---PALVSIPED-------VVQAEAGG 76
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H+V L + G V++ G N G L
Sbjct: 77 MHTVCLSKSGQVYSFGCNDEGAL 99
Score = 29.9 bits (64), Expect = 7.3
Identities = 21/94 (22%), Positives = 46/94 (48%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+ + A+S G +Y +GL++ QLG +E S +P+ + + ++ + + G
Sbjct: 250 YFTFAISHEGHVYGFGLSNYHQLGTPGTE----SCFIPQNLTSFKNSTKSWVGFSG---G 302
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V + +G ++ G +YG+L + K+
Sbjct: 303 QHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS 336
>BC007300-1|AAH07300.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLG-IKE------SENDLKSYALPKLVDLYDDNEEVHLQI 388
H + L+ GDLY G + GQLG + E L+ +PK V L H++
Sbjct: 183 HLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRF 242
Query: 389 KDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
+D CG+ + + +G V+ G + Y QL P
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP 275
Score = 39.5 bits (88), Expect = 0.009
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGL--NDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIAC 403
H+ AL++ G +++WG ++ G +G+ E +K +P V L + + +A
Sbjct: 130 HTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQL-------DVPVVKVAS 179
Query: 404 GSKHSVLLLEDGSVWTTGANKYGQL 478
G+ H V+L DG ++T G + GQL
Sbjct: 180 GNDHLVMLTADGDLYTLGCGEQGQL 204
Score = 33.5 bits (73), Expect = 0.60
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +E G + G D GQLG+ E+ + K P LV + +D + G
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK---PALVSIPED-------VVQAEAGG 76
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H+V L + G V++ G N G L
Sbjct: 77 MHTVCLSKSGQVYSFGCNDEGAL 99
Score = 29.9 bits (64), Expect = 7.3
Identities = 21/94 (22%), Positives = 46/94 (48%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+ + A+S G +Y +GL++ QLG +E S +P+ + + ++ + + G
Sbjct: 250 YFTFAISHEGHVYGFGLSNYHQLGTPGTE----SCFIPQNLTSFKNSTKSWVGFSG---G 302
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V + +G ++ G +YG+L + K+
Sbjct: 303 QHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS 336
>AL513497-2|CAI22287.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLG-IKE------SENDLKSYALPKLVDLYDDNEEVHLQI 388
H + L+ GDLY G + GQLG + E L+ +PK V L H++
Sbjct: 183 HLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRF 242
Query: 389 KDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
+D CG+ + + +G V+ G + Y QL P
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP 275
Score = 39.5 bits (88), Expect = 0.009
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGL--NDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIAC 403
H+ AL++ G +++WG ++ G +G+ E +K +P V L + + +A
Sbjct: 130 HTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQL-------DVPVVKVAS 179
Query: 404 GSKHSVLLLEDGSVWTTGANKYGQL 478
G+ H V+L DG ++T G + GQL
Sbjct: 180 GNDHLVMLTADGDLYTLGCGEQGQL 204
Score = 33.5 bits (73), Expect = 0.60
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +E G + G D GQLG+ E+ + K P LV + +D + G
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK---PALVSIPED-------VVQAEAGG 76
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H+V L + G V++ G N G L
Sbjct: 77 MHTVCLSKSGQVYSFGCNDEGAL 99
Score = 29.9 bits (64), Expect = 7.3
Identities = 21/94 (22%), Positives = 46/94 (48%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+ + A+S G +Y +GL++ QLG +E S +P+ + + ++ + + G
Sbjct: 250 YFTFAISHEGHVYGFGLSNYHQLGTPGTE----SCFIPQNLTSFKNSTKSWVGFSG---G 302
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V + +G ++ G +YG+L + K+
Sbjct: 303 QHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS 336
>AL050333-2|CAI23416.1| 1187|Homo sapiens RP1-93K22.1 protein.
Length = 1187
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/94 (31%), Positives = 48/94 (51%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+HS+ LS+ G +Y G G+LG D ++ +P+LV+ + + +A
Sbjct: 183 FHSVFLSQKGQVYTCGHGPGGRLG----HGDEQTCLVPRLVEGLNGHN-----CSQVAAA 233
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V+L EDG V+T G N + QL P+S N
Sbjct: 234 KDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCN 267
Score = 37.5 bits (83), Expect = 0.037
Identities = 36/124 (29%), Positives = 52/124 (41%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D P VE H++ L+E G +Y +GLN QLGI
Sbjct: 204 RLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPP 263
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQY 493
+ S +P+ + I +A G H+VL + +V+T G N GQL C
Sbjct: 264 S---SCNVPRQIQAKYLKGRT---IIGVAAGRFHTVLWTRE-AVYTMGLNG-GQLGCLLD 315
Query: 494 PNSK 505
PN +
Sbjct: 316 PNGE 319
>AF498924-1|AAM21072.1| 421|Homo sapiens regulator of chromosome
condensation 1 protein.
Length = 421
Score = 45.2 bits (102), Expect = 2e-04
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 7/93 (7%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLG-IKE------SENDLKSYALPKLVDLYDDNEEVHLQI 388
H + L+ GDLY G + GQLG + E L+ +PK V L H++
Sbjct: 183 HLVMLTADGDLYTLGCGEQGQLGRVPELFANRGGRQGLERLLVPKCVMLKSRGSRGHVRF 242
Query: 389 KDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
+D CG+ + + +G V+ G + Y QL P
Sbjct: 243 QDAFCGAYFTFAISHEGHVYGFGLSNYHQLGTP 275
Score = 39.5 bits (88), Expect = 0.009
Identities = 25/85 (29%), Positives = 45/85 (52%), Gaps = 2/85 (2%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGL--NDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIAC 403
H+ AL++ G +++WG ++ G +G+ E +K +P V L + + +A
Sbjct: 130 HTAALTDDGRVFLWGSFRDNNGVIGLLEP---MKKSMVPVQVQL-------DVPVVKVAS 179
Query: 404 GSKHSVLLLEDGSVWTTGANKYGQL 478
G+ H V+L DG ++T G + GQL
Sbjct: 180 GNDHLVMLTADGDLYTLGCGEQGQL 204
Score = 33.5 bits (73), Expect = 0.60
Identities = 25/83 (30%), Positives = 37/83 (44%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H +E G + G D GQLG+ E+ + K P LV + +D + G
Sbjct: 27 HRSHSTEPGLVLTLGQGDVGQLGLGENVMERKK---PALVSIPED-------VVQAEAGG 76
Query: 410 KHSVLLLEDGSVWTTGANKYGQL 478
H+V L + G V++ G N G L
Sbjct: 77 MHTVCLSKSGQVYSFGCNDEGAL 99
Score = 29.9 bits (64), Expect = 7.3
Identities = 21/94 (22%), Positives = 46/94 (48%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+ + A+S G +Y +GL++ QLG +E S +P+ + + ++ + + G
Sbjct: 250 YFTFAISHEGHVYGFGLSNYHQLGTPGTE----SCFIPQNLTSFKNSTKSWVGFSG---G 302
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V + +G ++ G +YG+L + K+
Sbjct: 303 QHHTVCMDSEGKAYSLGRAEYGRLGLGEGAEEKS 336
>AB037838-1|BAA92655.2| 1379|Homo sapiens KIAA1417 protein protein.
Length = 1379
Score = 45.2 bits (102), Expect = 2e-04
Identities = 30/94 (31%), Positives = 48/94 (51%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
+HS+ LS+ G +Y G G+LG D ++ +P+LV+ + + +A
Sbjct: 213 FHSVFLSQKGQVYTCGHGPGGRLG----HGDEQTCLVPRLVEGLNGHN-----CSQVAAA 263
Query: 407 SKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKN 508
H+V+L EDG V+T G N + QL P+S N
Sbjct: 264 KDHTVVLTEDGCVYTFGLNIFHQLGIIPPPSSCN 297
Score = 37.5 bits (83), Expect = 0.037
Identities = 36/124 (29%), Positives = 52/124 (41%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D P VE H++ L+E G +Y +GLN QLGI
Sbjct: 234 RLGHGDEQTCLVPRLVEGLNGHNCSQVAAAKDHTVVLTEDGCVYTFGLNIFHQLGIIPPP 293
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACPQY 493
+ S +P+ + I +A G H+VL + +V+T G N GQL C
Sbjct: 294 S---SCNVPRQIQAKYLKGRT---IIGVAAGRFHTVLWTRE-AVYTMGLNG-GQLGCLLD 345
Query: 494 PNSK 505
PN +
Sbjct: 346 PNGE 349
>BC113826-1|AAI13827.1| 244|Homo sapiens RCCD1 protein protein.
Length = 244
Score = 44.4 bits (100), Expect = 3e-04
Identities = 19/56 (33%), Positives = 27/56 (48%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGI 301
QLG P +E WHS+ +SE GD+Y+WG N++GQL +
Sbjct: 57 QLGHGTLEAELEPRLLEALQGLVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLAL 112
Score = 38.7 bits (86), Expect = 0.016
Identities = 20/63 (31%), Positives = 33/63 (52%), Gaps = 4/63 (6%)
Frame = +2
Query: 398 ACGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKV-CVIKEACRLK---CGPWT 565
+CGS+H+ ++ G ++T G KYGQL + +V + + ++K CGPW
Sbjct: 174 SCGSRHTAVVTRTGELYTWGWGKYGQLGHEDTTSLDRPRRVEYFVDKQLQVKAVTCGPWN 233
Query: 566 TVV 574
T V
Sbjct: 234 TYV 236
Score = 37.9 bits (84), Expect = 0.028
Identities = 20/59 (33%), Positives = 30/59 (50%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACG 406
H+ ++ G+LY WG GQLG D S P+ V+ + D + LQ+K + CG
Sbjct: 179 HTAVVTRTGELYTWGWGKYGQLG----HEDTTSLDRPRRVEYFVDKQ---LQVKAVTCG 230
Score = 33.5 bits (73), Expect = 0.60
Identities = 15/36 (41%), Positives = 22/36 (61%)
Frame = +2
Query: 380 LQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLACP 487
L + ++A G HSV + E G ++ G N+ GQLA P
Sbjct: 78 LVMAEVAAGGWHSVCVSETGDIYIWGWNESGQLALP 113
>BC040695-1|AAH40695.1| 358|Homo sapiens WBSCR16 protein protein.
Length = 358
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/88 (30%), Positives = 42/88 (47%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ L++ ++ G N GQ G K EN++ Y+ V D + Q+ +ACG
Sbjct: 185 HSLVLTDREGVFSMGNNSYGQCGRKVVENEI--YSESHRVHRMQDFDG---QVVQVACGQ 239
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQY 493
HS+ L + G V++ G GQ Y
Sbjct: 240 DHSLFLTDKGEVYSCGWGADGQTGLGHY 267
Score = 39.9 bits (89), Expect = 0.007
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 6/76 (7%)
Frame = +2
Query: 266 VWG--LNDTGQLGIKESENDLK---SYAL-PKLVDLYDDNEEVHLQIKDIACGSKHSVLL 427
VWG LN QLG S D Y L P V L D + ++ ++CG HS++L
Sbjct: 131 VWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQ-ETRVLQVSCGRAHSLVL 189
Query: 428 LEDGSVWTTGANKYGQ 475
+ V++ G N YGQ
Sbjct: 190 TDREGVFSMGNNSYGQ 205
>BC032712-1|AAH32712.1| 454|Homo sapiens WBSCR16 protein protein.
Length = 454
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/88 (30%), Positives = 42/88 (47%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ L++ ++ G N GQ G K EN++ Y+ V D + Q+ +ACG
Sbjct: 185 HSLVLTDREGVFSMGNNSYGQCGRKVVENEI--YSESHRVHRMQDFDG---QVVQVACGQ 239
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQY 493
HS+ L + G V++ G GQ Y
Sbjct: 240 DHSLFLTDKGEVYSCGWGADGQTGLGHY 267
Score = 39.9 bits (89), Expect = 0.007
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 6/76 (7%)
Frame = +2
Query: 266 VWG--LNDTGQLGIKESENDLK---SYAL-PKLVDLYDDNEEVHLQIKDIACGSKHSVLL 427
VWG LN QLG S D Y L P V L D + ++ ++CG HS++L
Sbjct: 131 VWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQ-ETRVLQVSCGRAHSLVL 189
Query: 428 LEDGSVWTTGANKYGQ 475
+ V++ G N YGQ
Sbjct: 190 TDREGVFSMGNNSYGQ 205
Score = 31.5 bits (68), Expect = 2.4
Identities = 15/37 (40%), Positives = 20/37 (54%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALP 340
H AL+ G+L+VWG N G LGI E+ + P
Sbjct: 405 HFAALTNKGELFVWGKNIRGCLGIGRLEDQYFPWRAP 441
>BC019008-1|AAH19008.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/88 (30%), Positives = 42/88 (47%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ L++ ++ G N GQ G K EN++ Y+ V D + Q+ +ACG
Sbjct: 185 HSLVLTDREGVFSMGNNSYGQCGRKVVENEI--YSESHRVHRMQDFDG---QVVQVACGQ 239
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQY 493
HS+ L + G V++ G GQ Y
Sbjct: 240 DHSLFLTDKGEVYSCGWGADGQTGLGHY 267
Score = 39.9 bits (89), Expect = 0.007
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 6/76 (7%)
Frame = +2
Query: 266 VWG--LNDTGQLGIKESENDLK---SYAL-PKLVDLYDDNEEVHLQIKDIACGSKHSVLL 427
VWG LN QLG S D Y L P V L D + ++ ++CG HS++L
Sbjct: 131 VWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQ-ETRVLQVSCGRAHSLVL 189
Query: 428 LEDGSVWTTGANKYGQ 475
+ V++ G N YGQ
Sbjct: 190 TDREGVFSMGNNSYGQ 205
Score = 31.9 bits (69), Expect = 1.8
Identities = 25/66 (37%), Positives = 31/66 (46%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H AL+ G+L+VWG N G LGI E+ P V + E V D+ACG
Sbjct: 405 HFAALTNKGELFVWGKNIRGCLGIGRLEDQY----FPWRVTM--PGEPV-----DVACGV 453
Query: 410 KHSVLL 427
H V L
Sbjct: 454 DHMVTL 459
>BC007823-1|AAH07823.1| 464|Homo sapiens Williams-Beuren syndrome
chromosome region 16 protein.
Length = 464
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/88 (30%), Positives = 42/88 (47%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ L++ ++ G N GQ G K EN++ Y+ V D + Q+ +ACG
Sbjct: 185 HSLVLTDREGVFSMGNNSYGQCGRKVVENEI--YSESHRVHRMQDFDG---QVVQVACGQ 239
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQY 493
HS+ L + G V++ G GQ Y
Sbjct: 240 DHSLFLTDKGEVYSCGWGADGQTGLGHY 267
Score = 39.9 bits (89), Expect = 0.007
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 6/76 (7%)
Frame = +2
Query: 266 VWG--LNDTGQLGIKESENDLK---SYAL-PKLVDLYDDNEEVHLQIKDIACGSKHSVLL 427
VWG LN QLG S D Y L P V L D + ++ ++CG HS++L
Sbjct: 131 VWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQ-ETRVLQVSCGRAHSLVL 189
Query: 428 LEDGSVWTTGANKYGQ 475
+ V++ G N YGQ
Sbjct: 190 TDREGVFSMGNNSYGQ 205
Score = 31.9 bits (69), Expect = 1.8
Identities = 25/66 (37%), Positives = 31/66 (46%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H AL+ G+L+VWG N G LGI E+ P V + E V D+ACG
Sbjct: 405 HFAALTNKGELFVWGKNIRGCLGIGRLEDQY----FPWRVTM--PGEPV-----DVACGV 453
Query: 410 KHSVLL 427
H V L
Sbjct: 454 DHMVTL 459
>AF410455-1|AAM62304.1| 464|Homo sapiens RCC1-like G exchanging
factor-like protein protein.
Length = 464
Score = 43.2 bits (97), Expect = 7e-04
Identities = 27/88 (30%), Positives = 42/88 (47%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
HS+ L++ ++ G N GQ G K EN++ Y+ V D + Q+ +ACG
Sbjct: 185 HSLVLTDREGVFSMGNNSYGQCGRKVVENEI--YSESHRVHRMQDFDG---QVVQVACGQ 239
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQY 493
HS+ L + G V++ G GQ Y
Sbjct: 240 DHSLFLTDKGEVYSCGWGADGQTGLGHY 267
Score = 39.9 bits (89), Expect = 0.007
Identities = 27/76 (35%), Positives = 37/76 (48%), Gaps = 6/76 (7%)
Frame = +2
Query: 266 VWG--LNDTGQLGIKESENDLK---SYAL-PKLVDLYDDNEEVHLQIKDIACGSKHSVLL 427
VWG LN QLG S D Y L P V L D + ++ ++CG HS++L
Sbjct: 131 VWGMGLNKDSQLGFHRSRKDKTRGYEYVLEPSPVSLPLDRPQ-ETRVLQVSCGRAHSLVL 189
Query: 428 LEDGSVWTTGANKYGQ 475
+ V++ G N YGQ
Sbjct: 190 TDREGVFSMGNNSYGQ 205
Score = 31.9 bits (69), Expect = 1.8
Identities = 25/66 (37%), Positives = 31/66 (46%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H AL+ G+L+VWG N G LGI E+ P V + E V D+ACG
Sbjct: 405 HFAALTNKGELFVWGKNIRGCLGIGRLEDQY----FPWRVTM--PGEPV-----DVACGV 453
Query: 410 KHSVLL 427
H V L
Sbjct: 454 DHMVTL 459
>BC112101-1|AAI12102.1| 979|Homo sapiens NIMA related kinase 9
protein.
Length = 979
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/153 (22%), Positives = 62/153 (40%), Gaps = 7/153 (4%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D + TP +V+ + L++ G + GLN+ +LG+ +
Sbjct: 511 RLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCM 570
Query: 314 NDLKSYA----LPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLA 481
+ + ++ +P + +I+ IA G H+ + E G + T G NK GQL
Sbjct: 571 SGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLG 630
Query: 482 CPQYPNSKNFNKV---CVIKEACRLKCGPWTTV 571
Y N + K+ R+ CG T+
Sbjct: 631 VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTI 663
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/115 (22%), Positives = 53/115 (46%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D ++ P VE ++ +++ G LY +G + G +G+ +
Sbjct: 405 QLGHGDKASYRQPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDK-- 462
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
A P++++ N + ++ ++CG H V+L + V++ G +YG+L
Sbjct: 463 -----VAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRL 512
Score = 40.3 bits (90), Expect = 0.005
Identities = 27/87 (31%), Positives = 43/87 (49%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + L+ ++Y WG + G+LG+ +SE D Y P+ VD+ L I + CG
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGL-DSEED---YYTPQKVDV-----PKALIIVAVQCGC 541
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQ 490
+ LL + G V G N++ +L Q
Sbjct: 542 DGTFLLTQSGKVLACGLNEFNKLGLNQ 568
>BC093881-1|AAH93881.1| 979|Homo sapiens NIMA (never in mitosis
gene a)- related kinase 9 protein.
Length = 979
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/153 (22%), Positives = 62/153 (40%), Gaps = 7/153 (4%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D + TP +V+ + L++ G + GLN+ +LG+ +
Sbjct: 511 RLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCM 570
Query: 314 NDLKSYA----LPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLA 481
+ + ++ +P + +I+ IA G H+ + E G + T G NK GQL
Sbjct: 571 SGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLG 630
Query: 482 CPQYPNSKNFNKV---CVIKEACRLKCGPWTTV 571
Y N + K+ R+ CG T+
Sbjct: 631 VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTI 663
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/115 (22%), Positives = 53/115 (46%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D ++ P VE ++ +++ G LY +G + G +G+ +
Sbjct: 405 QLGHGDKASYRQPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDK-- 462
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
A P++++ N + ++ ++CG H V+L + V++ G +YG+L
Sbjct: 463 -----VAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRL 512
Score = 40.3 bits (90), Expect = 0.005
Identities = 27/87 (31%), Positives = 43/87 (49%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + L+ ++Y WG + G+LG+ +SE D Y P+ VD+ L I + CG
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGL-DSEED---YYTPQKVDV-----PKALIIVAVQCGC 541
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQ 490
+ LL + G V G N++ +L Q
Sbjct: 542 DGTFLLTQSGKVLACGLNEFNKLGLNQ 568
>AY080896-1|AAL87410.1| 979|Homo sapiens NIMA-family kinase NERCC1
protein.
Length = 979
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/153 (22%), Positives = 62/153 (40%), Gaps = 7/153 (4%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D + TP +V+ + L++ G + GLN+ +LG+ +
Sbjct: 511 RLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCM 570
Query: 314 NDLKSYA----LPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLA 481
+ + ++ +P + +I+ IA G H+ + E G + T G NK GQL
Sbjct: 571 SGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLG 630
Query: 482 CPQYPNSKNFNKV---CVIKEACRLKCGPWTTV 571
Y N + K+ R+ CG T+
Sbjct: 631 VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTI 663
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/115 (22%), Positives = 53/115 (46%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D ++ P VE ++ +++ G LY +G + G +G+ +
Sbjct: 405 QLGHGDKASYRQPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDK-- 462
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
A P++++ N + ++ ++CG H V+L + V++ G +YG+L
Sbjct: 463 -----VAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRL 512
Score = 40.3 bits (90), Expect = 0.005
Identities = 27/87 (31%), Positives = 43/87 (49%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + L+ ++Y WG + G+LG+ +SE D Y P+ VD+ L I + CG
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGL-DSEED---YYTPQKVDV-----PKALIIVAVQCGC 541
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQ 490
+ LL + G V G N++ +L Q
Sbjct: 542 DGTFLLTQSGKVLACGLNEFNKLGLNQ 568
>AY048580-1|AAL05428.1| 979|Homo sapiens NIMA-related kinase Nek8
protein.
Length = 979
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/153 (22%), Positives = 62/153 (40%), Gaps = 7/153 (4%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D + TP +V+ + L++ G + GLN+ +LG+ +
Sbjct: 511 RLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCM 570
Query: 314 NDLKSYA----LPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLA 481
+ + ++ +P + +I+ IA G H+ + E G + T G NK GQL
Sbjct: 571 SGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLG 630
Query: 482 CPQYPNSKNFNKV---CVIKEACRLKCGPWTTV 571
Y N + K+ R+ CG T+
Sbjct: 631 VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTI 663
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/115 (22%), Positives = 53/115 (46%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D ++ P VE ++ +++ G LY +G + G +G+ +
Sbjct: 405 QLGHGDKASYRQPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDK-- 462
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
A P++++ N + ++ ++CG H V+L + V++ G +YG+L
Sbjct: 463 -----VAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRL 512
Score = 40.3 bits (90), Expect = 0.005
Identities = 27/87 (31%), Positives = 43/87 (49%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + L+ ++Y WG + G+LG+ +SE D Y P+ VD+ L I + CG
Sbjct: 491 HVVVLTRNKEVYSWGCGEYGRLGL-DSEED---YYTPQKVDV-----PKALIIVAVQCGC 541
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQ 490
+ LL + G V G N++ +L Q
Sbjct: 542 DGTFLLTQSGKVLACGLNEFNKLGLNQ 568
>AC007055-4|AAD31939.1| 414|Homo sapiens protein ( Homo sapiens
chromosome 14 clone BAC 201F1 map 14q24.3, complete
sequence. ).
Length = 414
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/153 (22%), Positives = 62/153 (40%), Gaps = 7/153 (4%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D + TP +V+ + L++ G + GLN+ +LG+ +
Sbjct: 181 RLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCM 240
Query: 314 NDLKSYA----LPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLA 481
+ + ++ +P + +I+ IA G H+ + E G + T G NK GQL
Sbjct: 241 SGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLG 300
Query: 482 CPQYPNSKNFNKV---CVIKEACRLKCGPWTTV 571
Y N + K+ R+ CG T+
Sbjct: 301 VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTI 333
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/115 (22%), Positives = 53/115 (46%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D ++ P VE ++ +++ G LY +G + G +G+ +
Sbjct: 75 QLGHGDKASYRQPKHVEKLQGKAIRQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDK-- 132
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
A P++++ N + ++ ++CG H V+L + V++ G +YG+L
Sbjct: 133 -----VAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRL 182
Score = 40.3 bits (90), Expect = 0.005
Identities = 27/87 (31%), Positives = 43/87 (49%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + L+ ++Y WG + G+LG+ +SE D Y P+ VD+ L I + CG
Sbjct: 161 HVVVLTRNKEVYSWGCGEYGRLGL-DSEED---YYTPQKVDV-----PKALIIVAVQCGC 211
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQ 490
+ LL + G V G N++ +L Q
Sbjct: 212 DGTFLLTQSGKVLACGLNEFNKLGLNQ 238
>AB082526-1|BAC02704.1| 1011|Homo sapiens KIAA1995 protein protein.
Length = 1011
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/153 (22%), Positives = 62/153 (40%), Gaps = 7/153 (4%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG D + TP +V+ + L++ G + GLN+ +LG+ +
Sbjct: 543 RLGLDSEEDYYTPQKVDVPKALIIVAVQCGCDGTFLLTQSGKVLACGLNEFNKLGLNQCM 602
Query: 314 NDLKSYA----LPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQLA 481
+ + ++ +P + +I+ IA G H+ + E G + T G NK GQL
Sbjct: 603 SGIINHEAYHEVPYTTSFTLAKQLSFYKIRTIAPGKTHTAAIDERGRLLTFGCNKCGQLG 662
Query: 482 CPQYPNSKNFNKV---CVIKEACRLKCGPWTTV 571
Y N + K+ R+ CG T+
Sbjct: 663 VGNYKKRLGINLLGGPLGGKQVIRVSCGDEFTI 695
Score = 41.5 bits (93), Expect = 0.002
Identities = 26/115 (22%), Positives = 53/115 (46%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D ++ P VE ++ +++ G LY +G + G +G+ +
Sbjct: 437 QLGHGDKASYRQPKHVEKLQGKAIHQVSCGDDFTVCVTDEGQLYAFGSDYYGCMGVDK-- 494
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
A P++++ N + ++ ++CG H V+L + V++ G +YG+L
Sbjct: 495 -----VAGPEVLEPMQLNFFLSNPVEQVSCGDNHVVVLTRNKEVYSWGCGEYGRL 544
Score = 40.3 bits (90), Expect = 0.005
Identities = 27/87 (31%), Positives = 43/87 (49%)
Frame = +2
Query: 230 HSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGS 409
H + L+ ++Y WG + G+LG+ +SE D Y P+ VD+ L I + CG
Sbjct: 523 HVVVLTRNKEVYSWGCGEYGRLGL-DSEED---YYTPQKVDV-----PKALIIVAVQCGC 573
Query: 410 KHSVLLLEDGSVWTTGANKYGQLACPQ 490
+ LL + G V G N++ +L Q
Sbjct: 574 DGTFLLTQSGKVLACGLNEFNKLGLNQ 600
>BC071576-1|AAH71576.1| 1237|Homo sapiens ALS2 protein protein.
Length = 1237
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/82 (29%), Positives = 37/82 (45%)
Frame = +2
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
+++ WG GQLG D+ P V D E +HL+ G HS+ L
Sbjct: 527 EVWTWGKGKEGQLG----HGDVLPRLQPLCVKCLDGKEVIHLE-----AGGYHSLALTAK 577
Query: 437 GSVWTTGANKYGQLACPQYPNS 502
V++ G+N +GQL +P +
Sbjct: 578 SQVYSWGSNTFGQLGHSDFPTT 599
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEE--VHLQIKDIA 400
+HS A+++ G Y+WG N GQ + + P V + D + ++I +A
Sbjct: 101 FHSGAVTDNGVAYMWGENSAGQCAVANQQ----YVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 401 CGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSK 505
CG +H++ L +W G L +P +K
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQLGLITTAFPVTK 191
Score = 34.3 bits (75), Expect = 0.34
Identities = 27/100 (27%), Positives = 43/100 (43%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D P V+ +HS+AL+ +Y WG N GQLG
Sbjct: 538 QLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG----H 593
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLE 433
+D + +P+L + +N + IA G +S+ L++
Sbjct: 594 SDFPT-TVPRLAKISSEN-----GVWSIAAGRDYSLFLVD 627
>BC029174-1|AAH29174.1| 812|Homo sapiens ALS2 protein protein.
Length = 812
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/82 (29%), Positives = 37/82 (45%)
Frame = +2
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
+++ WG GQLG D+ P V D E +HL+ G HS+ L
Sbjct: 527 EVWTWGKGKEGQLG----HGDVLPRLQPLCVKCLDGKEVIHLE-----AGGYHSLALTAK 577
Query: 437 GSVWTTGANKYGQLACPQYPNS 502
V++ G+N +GQL +P +
Sbjct: 578 SQVYSWGSNTFGQLGHSDFPTT 599
Score = 34.3 bits (75), Expect = 0.34
Identities = 27/100 (27%), Positives = 43/100 (43%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D P V+ +HS+AL+ +Y WG N GQLG
Sbjct: 538 QLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG----H 593
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLE 433
+D + +P+L + +N + IA G +S+ L++
Sbjct: 594 SDFPT-TVPRLAKISSEN-----GVWSIAAGRDYSLFLVD 627
Score = 33.9 bits (74), Expect = 0.45
Identities = 23/95 (24%), Positives = 41/95 (43%), Gaps = 2/95 (2%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIK--DIA 400
+HS A+++ G Y+ G N GQ + + + P V + D L ++ +A
Sbjct: 101 FHSGAVTDNGVAYMCGENSAGQCAVANQQYVPE----PNPVSIADSEASPLLAVRILQLA 156
Query: 401 CGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSK 505
CG +H++ L +W G L +P +K
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQLGLITTAFPVTK 191
>AF391100-1|AAL14103.1| 1657|Homo sapiens alsin protein.
Length = 1657
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/82 (29%), Positives = 37/82 (45%)
Frame = +2
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
+++ WG GQLG D+ P V D E +HL+ G HS+ L
Sbjct: 527 EVWTWGKGKEGQLG----HGDVLPRLQPLCVKCLDGKEVIHLE-----AGGYHSLALTAK 577
Query: 437 GSVWTTGANKYGQLACPQYPNS 502
V++ G+N +GQL +P +
Sbjct: 578 SQVYSWGSNTFGQLGHSDFPTT 599
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEE--VHLQIKDIA 400
+HS A+++ G Y+WG N GQ + + P V + D + ++I +A
Sbjct: 101 FHSGAVTDNGVAYMWGENSAGQCAVANQQ----YVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 401 CGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSK 505
CG +H++ L +W G L +P +K
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQLGLITTAFPVTK 191
Score = 34.3 bits (75), Expect = 0.34
Identities = 27/100 (27%), Positives = 43/100 (43%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D P V+ +HS+AL+ +Y WG N GQLG
Sbjct: 538 QLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG----H 593
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLE 433
+D + +P+L + +N + IA G +S+ L++
Sbjct: 594 SDFPT-TVPRLAKISSEN-----GVWSIAAGRDYSLFLVD 627
>AC007279-1|AAY15058.1| 1598|Homo sapiens unknown protein.
Length = 1598
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/82 (29%), Positives = 37/82 (45%)
Frame = +2
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
+++ WG GQLG D+ P V D E +HL+ G HS+ L
Sbjct: 468 EVWTWGKGKEGQLG----HGDVLPRLQPLCVKCLDGKEVIHLE-----AGGYHSLALTAK 518
Query: 437 GSVWTTGANKYGQLACPQYPNS 502
V++ G+N +GQL +P +
Sbjct: 519 SQVYSWGSNTFGQLGHSDFPTT 540
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEE--VHLQIKDIA 400
+HS A+++ G Y+WG N GQ + + P V + D + ++I +A
Sbjct: 42 FHSGAVTDNGVAYMWGENSAGQCAVANQQ----YVPEPNPVSIADSEASPLLAVRILQLA 97
Query: 401 CGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSK 505
CG +H++ L +W G L +P +K
Sbjct: 98 CGEEHTLALSISREIWAWGTGCQLGLITTAFPVTK 132
Score = 34.3 bits (75), Expect = 0.34
Identities = 27/100 (27%), Positives = 43/100 (43%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D P V+ +HS+AL+ +Y WG N GQLG
Sbjct: 479 QLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG----H 534
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLE 433
+D + +P+L + +N + IA G +S+ L++
Sbjct: 535 SDFPT-TVPRLAKISSEN-----GVWSIAAGRDYSLFLVD 568
>AB053305-1|BAB69014.1| 1657|Homo sapiens ALS2 protein.
Length = 1657
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/82 (29%), Positives = 37/82 (45%)
Frame = +2
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
+++ WG GQLG D+ P V D E +HL+ G HS+ L
Sbjct: 527 EVWTWGKGKEGQLG----HGDVLPRLQPLCVKCLDGKEVIHLE-----AGGYHSLALTAK 577
Query: 437 GSVWTTGANKYGQLACPQYPNS 502
V++ G+N +GQL +P +
Sbjct: 578 SQVYSWGSNTFGQLGHSDFPTT 599
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEE--VHLQIKDIA 400
+HS A+++ G Y+WG N GQ + + P V + D + ++I +A
Sbjct: 101 FHSGAVTDNGVAYMWGENSAGQCAVANQQ----YVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 401 CGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSK 505
CG +H++ L +W G L +P +K
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQLGLITTAFPVTK 191
Score = 34.3 bits (75), Expect = 0.34
Identities = 27/100 (27%), Positives = 43/100 (43%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D P V+ +HS+AL+ +Y WG N GQLG
Sbjct: 538 QLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG----H 593
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLE 433
+D + +P+L + +N + IA G +S+ L++
Sbjct: 594 SDFPT-TVPRLAKISSEN-----GVWSIAAGRDYSLFLVD 627
>AB046783-1|BAB13389.2| 1658|Homo sapiens KIAA1563 protein protein.
Length = 1658
Score = 40.7 bits (91), Expect = 0.004
Identities = 24/82 (29%), Positives = 37/82 (45%)
Frame = +2
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLED 436
+++ WG GQLG D+ P V D E +HL+ G HS+ L
Sbjct: 528 EVWTWGKGKEGQLG----HGDVLPRLQPLCVKCLDGKEVIHLE-----AGGYHSLALTAK 578
Query: 437 GSVWTTGANKYGQLACPQYPNS 502
V++ G+N +GQL +P +
Sbjct: 579 SQVYSWGSNTFGQLGHSDFPTT 600
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEE--VHLQIKDIA 400
+HS A+++ G Y+WG N GQ + + P V + D + ++I +A
Sbjct: 102 FHSGAVTDNGVAYMWGENSAGQCAVANQQ----YVPEPNPVSIADSEASPLLAVRILQLA 157
Query: 401 CGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSK 505
CG +H++ L +W G L +P +K
Sbjct: 158 CGEEHTLALSISREIWAWGTGCQLGLITTAFPVTK 192
Score = 34.3 bits (75), Expect = 0.34
Identities = 27/100 (27%), Positives = 43/100 (43%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
QLG D P V+ +HS+AL+ +Y WG N GQLG
Sbjct: 539 QLGHGDVLPRLQPLCVKCLDGKEVIHLEAGGYHSLALTAKSQVYSWGSNTFGQLG----H 594
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLE 433
+D + +P+L + +N + IA G +S+ L++
Sbjct: 595 SDFPT-TVPRLAKISSEN-----GVWSIAAGRDYSLFLVD 628
>AK023024-1|BAB14362.1| 396|Homo sapiens protein ( Homo sapiens
cDNA FLJ12962 fis, clone NT2RP2005694, weakly similar to
X-LINKED RETINITIS PIGMENTOSA GTPASE REGULATOR. ).
Length = 396
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEE--VHLQIKDIA 400
+HS A+++ G Y+WG N GQ + + P V + D + ++I +A
Sbjct: 101 FHSGAVTDNGVAYMWGENSAGQCAVANQQ----YVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 401 CGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSK 505
CG +H++ L +W G L +P +K
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQLGLITTAFPVTK 191
>AB053306-1|BAB69015.1| 396|Homo sapiens ALS2 protein.
Length = 396
Score = 39.1 bits (87), Expect = 0.012
Identities = 24/95 (25%), Positives = 42/95 (44%), Gaps = 2/95 (2%)
Frame = +2
Query: 227 WHSMALSEFGDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEE--VHLQIKDIA 400
+HS A+++ G Y+WG N GQ + + P V + D + ++I +A
Sbjct: 101 FHSGAVTDNGVAYMWGENSAGQCAVANQQ----YVPEPNPVSIADSEASPLLAVRILQLA 156
Query: 401 CGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSK 505
CG +H++ L +W G L +P +K
Sbjct: 157 CGEEHTLALSISREIWAWGTGCQLGLITTAFPVTK 191
>BC040929-1|AAH40929.1| 651|Homo sapiens HERC1 protein protein.
Length = 651
Score = 37.9 bits (84), Expect = 0.028
Identities = 21/63 (33%), Positives = 28/63 (44%), Gaps = 1/63 (1%)
Frame = +2
Query: 116 FNQWRL-QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQ 292
F Q RL L + N P Q+ H++AL+ GD+Y WG N GQ
Sbjct: 53 FGQDRLIGLPEGRARNHNRPQQIPVLAGVIIEDVAVGAEHTLALASNGDVYAWGSNSEGQ 112
Query: 293 LGI 301
LG+
Sbjct: 113 LGL 115
Score = 36.7 bits (81), Expect = 0.064
Identities = 26/115 (22%), Positives = 53/115 (46%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG +++ +P +++ S+AL++ G +Y +G + L +
Sbjct: 8 KLGLGNSTAKSSPQKIDVLCGIGIKKVACGTQFSVALTKDGHVYTFGQDRLIGLPEGRAR 67
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLEDGSVWTTGANKYGQL 478
N + +P L + I+D+A G++H++ L +G V+ G+N GQL
Sbjct: 68 NHNRPQQIPVLAGVI---------IEDVAVGAEHTLALASNGDVYAWGSNSEGQL 113
>AC004460-2|AAC06339.1| 371|Homo sapiens WUGSC:H_DJ1086D14.2
protein.
Length = 371
Score = 37.5 bits (83), Expect = 0.037
Identities = 28/96 (29%), Positives = 40/96 (41%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXWHSMALSEFGDLYVWGLNDTGQLGIKESE 313
+LG ++ P VE H +A+ + G +Y WG ND GQ G +
Sbjct: 65 RLGHRSDVHVRKPQVVEGLRGKKIVHVAVGAQHCLAVMDSGQVYAWGDNDHGQQGNGTTT 124
Query: 314 NDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSV 421
+ K P LV + + I +ACGS HSV
Sbjct: 125 VNRK----PMLVQGLEGQK-----IMCVACGSSHSV 151
Score = 29.5 bits (63), Expect = 9.7
Identities = 21/75 (28%), Positives = 35/75 (46%)
Frame = +2
Query: 254 GDLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDIACGSKHSVLLLE 433
G ++ WG D G+LG SE +P+ ++ + + I CG++ + L +
Sbjct: 1 GLVFSWGDGDFGKLGRGGSEG----CNIPQNIERLNGQG-----VCQIECGAQFLLALTK 51
Query: 434 DGSVWTTGANKYGQL 478
G VWT G Y +L
Sbjct: 52 SGVVWTWGKGDYFRL 66
>BC067293-1|AAH67293.1| 580|Homo sapiens F-box protein 24 protein.
Length = 580
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/53 (32%), Positives = 25/53 (47%)
Frame = +2
Query: 398 ACGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLKCG 556
A G H L+ E G ++ G N+YGQL + +VC ++ L CG
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPITLWCG 415
>AF225404-1|AAO27482.1| 259|Homo sapiens HERC2 protein.
Length = 259
Score = 32.3 bits (70), Expect = 1.4
Identities = 18/57 (31%), Positives = 27/57 (47%), Gaps = 2/57 (3%)
Frame = +2
Query: 134 QLGQDDTSNLETPTQVEXXXXXXXXXXXXXXW--HSMALSEFGDLYVWGLNDTGQLG 298
+LG T ++ TPT +E H +ALS G++Y WG + G+LG
Sbjct: 191 RLGIGGTESVSTPTLLESIQHVFIKKVAVNSGGKHCLALSSEGEVYSWGEAEDGKLG 247
>AC069281-1|AAP21863.1| 580|Homo sapiens unknown protein.
Length = 580
Score = 32.3 bits (70), Expect = 1.4
Identities = 17/53 (32%), Positives = 25/53 (47%)
Frame = +2
Query: 398 ACGSKHSVLLLEDGSVWTTGANKYGQLACPQYPNSKNFNKVCVIKEACRLKCG 556
A G H L+ E G ++ G N+YGQL + +VC ++ L CG
Sbjct: 363 ALGYNHLGLVDEFGRIFMQGNNRYGQLGTGDKMDRGEPTQVCYLQRPITLWCG 415
>AB051514-1|BAB21818.1| 1130|Homo sapiens KIAA1727 protein protein.
Length = 1130
Score = 30.3 bits (65), Expect = 5.5
Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 3/70 (4%)
Frame = +2
Query: 257 DLYVWGLNDTGQLGIKESENDLKSYALPKLVDLYDDNEEVHLQIKDI-ACGSKHSV--LL 427
D +++GL ++ LK LP LY D + IK++ +C HS+ L+
Sbjct: 226 DSFLYGLIQVPNYSLRIEAMVLKKEFLPSCSSLYTDITVLRTAIKELMSCEELHSILHLV 285
Query: 428 LEDGSVWTTG 457
L+ G++ G
Sbjct: 286 LQAGNIMNAG 295
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,103,597
Number of Sequences: 237096
Number of extensions: 1943678
Number of successful extensions: 3929
Number of sequences better than 10.0: 102
Number of HSP's better than 10.0 without gapping: 3327
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3701
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6466646650
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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