Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12b08f
(683 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC008324-1|AAH08324.1| 273|Homo sapiens splA/ryanodine receptor... 138 1e-32
AK056367-1|BAB71165.1| 273|Homo sapiens protein ( Homo sapiens ... 138 1e-32
AF403029-1|AAL57348.1| 273|Homo sapiens SPRY domain-containing ... 138 1e-32
AB209559-1|BAD92796.1| 371|Homo sapiens SPRY domain-containing ... 138 2e-32
BC015711-1|AAH15711.1| 273|Homo sapiens splA/ryanodine receptor... 133 5e-31
AL358252-1|CAI14376.2| 273|Homo sapiens splA/ryanodine receptor... 133 5e-31
AL008734-2|CAM12844.1| 202|Homo sapiens splA/ryanodine receptor... 133 5e-31
AL008734-1|CAM12843.1| 273|Homo sapiens splA/ryanodine receptor... 133 5e-31
AF403026-1|AAL57345.1| 273|Homo sapiens SPRY domain-containing ... 133 5e-31
AK026046-1|BAB15335.1| 273|Homo sapiens protein ( Homo sapiens ... 130 3e-30
U47924-10|AAB51328.1| 263|Homo sapiens C9 protein. 103 8e-22
BC071933-1|AAH71933.1| 263|Homo sapiens SPSB2 protein protein. 103 8e-22
BC002983-1|AAH02983.1| 263|Homo sapiens splA/ryanodine receptor... 103 8e-22
AF403027-1|AAL57346.1| 263|Homo sapiens SPRY domain-containing ... 103 8e-22
BC047441-1|AAH47441.2| 355|Homo sapiens splA/ryanodine receptor... 31 3.8
BC024244-1|AAH24244.1| 355|Homo sapiens splA/ryanodine receptor... 31 3.8
BC007588-1|AAH07588.2| 355|Homo sapiens splA/ryanodine receptor... 31 3.8
AF403028-1|AAL57347.1| 355|Homo sapiens SPRY domain-containing ... 31 3.8
>BC008324-1|AAH08324.1| 273|Homo sapiens splA/ryanodine receptor
domain and SOCS box containing 4 protein.
Length = 273
Score = 138 bits (335), Expect = 1e-32
Identities = 67/124 (54%), Positives = 78/124 (62%)
Frame = +2
Query: 296 MGQKLSGGVKSVSRECTAPFKAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKHAWNPN 475
MGQKLSG +KSV A + QL+HAWNP
Sbjct: 1 MGQKLSGSLKSVEVREPA-LRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPE 59
Query: 476 DRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVAT 655
DRSLN+FVK++D LTFHRHPVAQSTD IRG+ G+ RGLH W++ WPARQRGTHAVVGVAT
Sbjct: 60 DRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVAT 119
Query: 656 SHAP 667
+ AP
Sbjct: 120 ARAP 123
>AK056367-1|BAB71165.1| 273|Homo sapiens protein ( Homo sapiens
cDNA FLJ31805 fis, clone NT2RI2009144. ).
Length = 273
Score = 138 bits (335), Expect = 1e-32
Identities = 67/124 (54%), Positives = 78/124 (62%)
Frame = +2
Query: 296 MGQKLSGGVKSVSRECTAPFKAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKHAWNPN 475
MGQKLSG +KSV A + QL+HAWNP
Sbjct: 1 MGQKLSGSLKSVEVREPA-LRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPE 59
Query: 476 DRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVAT 655
DRSLN+FVK++D LTFHRHPVAQSTD IRG+ G+ RGLH W++ WPARQRGTHAVVGVAT
Sbjct: 60 DRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVAT 119
Query: 656 SHAP 667
+ AP
Sbjct: 120 ARAP 123
>AF403029-1|AAL57348.1| 273|Homo sapiens SPRY domain-containing
SOCS box protein SSB-4 protein.
Length = 273
Score = 138 bits (335), Expect = 1e-32
Identities = 67/124 (54%), Positives = 78/124 (62%)
Frame = +2
Query: 296 MGQKLSGGVKSVSRECTAPFKAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKHAWNPN 475
MGQKLSG +KSV A + QL+HAWNP
Sbjct: 1 MGQKLSGSLKSVEVREPA-LRPAKRELRGAEPGRPARLDQLLDMPAAGLAVQLRHAWNPE 59
Query: 476 DRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVAT 655
DRSLN+FVK++D LTFHRHPVAQSTD IRG+ G+ RGLH W++ WPARQRGTHAVVGVAT
Sbjct: 60 DRSLNVFVKDDDRLTFHRHPVAQSTDGIRGKVGHARGLHAWQINWPARQRGTHAVVGVAT 119
Query: 656 SHAP 667
+ AP
Sbjct: 120 ARAP 123
>AB209559-1|BAD92796.1| 371|Homo sapiens SPRY domain-containing
SOCS box protein SSB-1 variant protein.
Length = 371
Score = 138 bits (333), Expect = 2e-32
Identities = 67/128 (52%), Positives = 82/128 (64%), Gaps = 1/128 (0%)
Frame = +2
Query: 287 GMNMGQKLSGGVKSVS-RECTAPFKAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKHA 463
G NMGQK++GG+K+V R+ T ++ + QL H+
Sbjct: 96 GANMGQKVTGGIKTVDLRDPT--YRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHS 153
Query: 464 WNPNDRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVV 643
WN NDRSLN+FVKE+D L FHRHPVAQSTD IRG+ GYTRGLH W++ W RQRGTHAVV
Sbjct: 154 WNNNDRSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVV 213
Query: 644 GVATSHAP 667
GVAT+ AP
Sbjct: 214 GVATADAP 221
>BC015711-1|AAH15711.1| 273|Homo sapiens splA/ryanodine receptor
domain and SOCS box containing 1 protein.
Length = 273
Score = 133 bits (322), Expect = 5e-31
Identities = 63/124 (50%), Positives = 77/124 (62%)
Frame = +2
Query: 296 MGQKLSGGVKSVSRECTAPFKAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKHAWNPN 475
MGQK++GG+K+V ++ + QL H+WN N
Sbjct: 1 MGQKVTGGIKTVDMR-DPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNN 59
Query: 476 DRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVAT 655
DRSLN+FVKE+D L FHRHPVAQSTD IRG+ GYTRGLH W++ W RQRGTHAVVGVAT
Sbjct: 60 DRSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVAT 119
Query: 656 SHAP 667
+ AP
Sbjct: 120 ADAP 123
>AL358252-1|CAI14376.2| 273|Homo sapiens splA/ryanodine receptor
domain and SOCS box containing 1 protein.
Length = 273
Score = 133 bits (322), Expect = 5e-31
Identities = 63/124 (50%), Positives = 77/124 (62%)
Frame = +2
Query: 296 MGQKLSGGVKSVSRECTAPFKAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKHAWNPN 475
MGQK++GG+K+V ++ + QL H+WN N
Sbjct: 1 MGQKVTGGIKTVDMR-DPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNN 59
Query: 476 DRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVAT 655
DRSLN+FVKE+D L FHRHPVAQSTD IRG+ GYTRGLH W++ W RQRGTHAVVGVAT
Sbjct: 60 DRSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVAT 119
Query: 656 SHAP 667
+ AP
Sbjct: 120 ADAP 123
>AL008734-2|CAM12844.1| 202|Homo sapiens splA/ryanodine receptor
domain and SOCS box containing 1 protein.
Length = 202
Score = 133 bits (322), Expect = 5e-31
Identities = 63/124 (50%), Positives = 77/124 (62%)
Frame = +2
Query: 296 MGQKLSGGVKSVSRECTAPFKAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKHAWNPN 475
MGQK++GG+K+V ++ + QL H+WN N
Sbjct: 1 MGQKVTGGIKTVDMR-DPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNN 59
Query: 476 DRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVAT 655
DRSLN+FVKE+D L FHRHPVAQSTD IRG+ GYTRGLH W++ W RQRGTHAVVGVAT
Sbjct: 60 DRSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVAT 119
Query: 656 SHAP 667
+ AP
Sbjct: 120 ADAP 123
>AL008734-1|CAM12843.1| 273|Homo sapiens splA/ryanodine receptor
domain and SOCS box containing 1 protein.
Length = 273
Score = 133 bits (322), Expect = 5e-31
Identities = 63/124 (50%), Positives = 77/124 (62%)
Frame = +2
Query: 296 MGQKLSGGVKSVSRECTAPFKAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKHAWNPN 475
MGQK++GG+K+V ++ + QL H+WN N
Sbjct: 1 MGQKVTGGIKTVDMR-DPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNN 59
Query: 476 DRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVAT 655
DRSLN+FVKE+D L FHRHPVAQSTD IRG+ GYTRGLH W++ W RQRGTHAVVGVAT
Sbjct: 60 DRSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVAT 119
Query: 656 SHAP 667
+ AP
Sbjct: 120 ADAP 123
>AF403026-1|AAL57345.1| 273|Homo sapiens SPRY domain-containing
SOCS box protein SSB-1 protein.
Length = 273
Score = 133 bits (322), Expect = 5e-31
Identities = 63/124 (50%), Positives = 77/124 (62%)
Frame = +2
Query: 296 MGQKLSGGVKSVSRECTAPFKAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKHAWNPN 475
MGQK++GG+K+V ++ + QL H+WN N
Sbjct: 1 MGQKVTGGIKTVDMR-DPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNN 59
Query: 476 DRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVAT 655
DRSLN+FVKE+D L FHRHPVAQSTD IRG+ GYTRGLH W++ W RQRGTHAVVGVAT
Sbjct: 60 DRSLNVFVKEDDKLIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVAT 119
Query: 656 SHAP 667
+ AP
Sbjct: 120 ADAP 123
>AK026046-1|BAB15335.1| 273|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22393 fis, clone HRC07880. ).
Length = 273
Score = 130 bits (315), Expect = 3e-30
Identities = 62/124 (50%), Positives = 76/124 (61%)
Frame = +2
Query: 296 MGQKLSGGVKSVSRECTAPFKAVVXXXXXXXXXXXXXXXXXXXXXXXXXXXQLKHAWNPN 475
MGQK++GG+K+V ++ + QL H+WN N
Sbjct: 1 MGQKVTGGIKTVDMR-DPTYRPLKQELQGLDYCKPTRLDLLLDMPPVSYDVQLLHSWNNN 59
Query: 476 DRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVAT 655
DRSLN+FVKE+D FHRHPVAQSTD IRG+ GYTRGLH W++ W RQRGTHAVVGVAT
Sbjct: 60 DRSLNVFVKEDDKPIFHRHPVAQSTDAIRGKVGYTRGLHVWQITWAMRQRGTHAVVGVAT 119
Query: 656 SHAP 667
+ AP
Sbjct: 120 ADAP 123
>U47924-10|AAB51328.1| 263|Homo sapiens C9 protein.
Length = 263
Score = 103 bits (246), Expect = 8e-22
Identities = 48/73 (65%), Positives = 53/73 (72%)
Frame = +2
Query: 449 QLKHAWNPNDRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRG 628
Q +H WNP D S NI VKE L F R PVAQSTD RG+ GY+RGLH WE+ WP QRG
Sbjct: 43 QRRHGWNPKDCSENIEVKE-GGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRG 101
Query: 629 THAVVGVATSHAP 667
THAVVGVAT+ AP
Sbjct: 102 THAVVGVATALAP 114
>BC071933-1|AAH71933.1| 263|Homo sapiens SPSB2 protein protein.
Length = 263
Score = 103 bits (246), Expect = 8e-22
Identities = 48/73 (65%), Positives = 53/73 (72%)
Frame = +2
Query: 449 QLKHAWNPNDRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRG 628
Q +H WNP D S NI VKE L F R PVAQSTD RG+ GY+RGLH WE+ WP QRG
Sbjct: 43 QRRHGWNPKDCSENIEVKE-GGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRG 101
Query: 629 THAVVGVATSHAP 667
THAVVGVAT+ AP
Sbjct: 102 THAVVGVATALAP 114
>BC002983-1|AAH02983.1| 263|Homo sapiens splA/ryanodine receptor
domain and SOCS box containing 2 protein.
Length = 263
Score = 103 bits (246), Expect = 8e-22
Identities = 48/73 (65%), Positives = 53/73 (72%)
Frame = +2
Query: 449 QLKHAWNPNDRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRG 628
Q +H WNP D S NI VKE L F R PVAQSTD RG+ GY+RGLH WE+ WP QRG
Sbjct: 43 QRRHGWNPKDCSENIEVKE-GGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRG 101
Query: 629 THAVVGVATSHAP 667
THAVVGVAT+ AP
Sbjct: 102 THAVVGVATALAP 114
>AF403027-1|AAL57346.1| 263|Homo sapiens SPRY domain-containing
SOCS box protein SSB-2 protein.
Length = 263
Score = 103 bits (246), Expect = 8e-22
Identities = 48/73 (65%), Positives = 53/73 (72%)
Frame = +2
Query: 449 QLKHAWNPNDRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRG 628
Q +H WNP D S NI VKE L F R PVAQSTD RG+ GY+RGLH WE+ WP QRG
Sbjct: 43 QRRHGWNPKDCSENIEVKE-GGLYFERRPVAQSTDGARGKRGYSRGLHAWEISWPLEQRG 101
Query: 629 THAVVGVATSHAP 667
THAVVGVAT+ AP
Sbjct: 102 THAVVGVATALAP 114
>BC047441-1|AAH47441.2| 355|Homo sapiens splA/ryanodine receptor
domain and SOCS box containing 3 protein.
Length = 355
Score = 31.1 bits (67), Expect = 3.8
Identities = 18/62 (29%), Positives = 27/62 (43%)
Frame = +2
Query: 473 NDRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVA 652
N S + + ++FH + T IRG G H WE+ + GT +VG+
Sbjct: 111 NKSSATLLSCDNRKVSFHME-YSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIG 169
Query: 653 TS 658
TS
Sbjct: 170 TS 171
>BC024244-1|AAH24244.1| 355|Homo sapiens splA/ryanodine receptor
domain and SOCS box containing 3 protein.
Length = 355
Score = 31.1 bits (67), Expect = 3.8
Identities = 18/62 (29%), Positives = 27/62 (43%)
Frame = +2
Query: 473 NDRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVA 652
N S + + ++FH + T IRG G H WE+ + GT +VG+
Sbjct: 111 NKSSATLLSCDNRKVSFHME-YSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIG 169
Query: 653 TS 658
TS
Sbjct: 170 TS 171
>BC007588-1|AAH07588.2| 355|Homo sapiens splA/ryanodine receptor
domain and SOCS box containing 3 protein.
Length = 355
Score = 31.1 bits (67), Expect = 3.8
Identities = 18/62 (29%), Positives = 27/62 (43%)
Frame = +2
Query: 473 NDRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVA 652
N S + + ++FH + T IRG G H WE+ + GT +VG+
Sbjct: 111 NKSSATLLSCDNRKVSFHME-YSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIG 169
Query: 653 TS 658
TS
Sbjct: 170 TS 171
>AF403028-1|AAL57347.1| 355|Homo sapiens SPRY domain-containing
SOCS box protein SSB-3 protein.
Length = 355
Score = 31.1 bits (67), Expect = 3.8
Identities = 18/62 (29%), Positives = 27/62 (43%)
Frame = +2
Query: 473 NDRSLNIFVKEEDALTFHRHPVAQSTDCIRGRTGYTRGLHCWEVVWPARQRGTHAVVGVA 652
N S + + ++FH + T IRG G H WE+ + GT +VG+
Sbjct: 111 NKSSATLLSCDNRKVSFHME-YSCGTAAIRGTKELGEGQHFWEIKMTSPVYGTDMMVGIG 169
Query: 653 TS 658
TS
Sbjct: 170 TS 171
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 76,466,530
Number of Sequences: 237096
Number of extensions: 1130519
Number of successful extensions: 3129
Number of sequences better than 10.0: 18
Number of HSP's better than 10.0 without gapping: 3011
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3121
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7783251346
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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