Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12a11r
(507 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 116 4e-25
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 113 2e-24
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 111 1e-23
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 99 3e-20
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 100 4e-20
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 99 7e-20
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 98 9e-20
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 97 2e-19
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 97 2e-19
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 95 6e-19
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 95 8e-19
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 95 1e-18
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 95 1e-18
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 94 2e-18
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 93 3e-18
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 93 4e-18
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 91 1e-17
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 91 2e-17
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 90 2e-17
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 87 3e-16
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 86 4e-16
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 86 4e-16
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 86 5e-16
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 85 1e-15
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 85 1e-15
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 82 6e-15
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 82 8e-15
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 82 8e-15
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 80 2e-14
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 79 4e-14
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 79 6e-14
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 79 8e-14
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 77 2e-13
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 77 3e-13
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 76 5e-13
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 75 9e-13
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 74 2e-12
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 74 2e-12
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 74 2e-12
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 74 2e-12
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 73 3e-12
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 73 3e-12
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 73 4e-12
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 71 1e-11
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 71 1e-11
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 71 1e-11
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 71 1e-11
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 70 3e-11
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 70 3e-11
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 70 3e-11
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 69 5e-11
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 69 5e-11
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 69 6e-11
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 69 8e-11
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 69 8e-11
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 68 1e-10
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 68 1e-10
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 68 1e-10
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 67 2e-10
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 67 2e-10
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 67 2e-10
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 67 2e-10
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 66 3e-10
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 66 3e-10
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 66 4e-10
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 66 6e-10
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 66 6e-10
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 66 6e-10
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 66 6e-10
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 65 8e-10
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 65 1e-09
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 64 1e-09
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 64 1e-09
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 64 2e-09
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 64 2e-09
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 64 2e-09
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 64 2e-09
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 63 3e-09
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 63 3e-09
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 63 3e-09
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 63 4e-09
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 63 4e-09
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 63 4e-09
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 63 4e-09
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 63 4e-09
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 63 4e-09
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 62 5e-09
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 62 5e-09
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 62 7e-09
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 62 7e-09
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 62 7e-09
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 62 7e-09
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 62 9e-09
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 62 9e-09
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 62 9e-09
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 61 1e-08
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 61 2e-08
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 61 2e-08
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 60 2e-08
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 60 3e-08
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 60 3e-08
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 60 3e-08
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 60 3e-08
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 60 4e-08
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 60 4e-08
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 59 5e-08
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 59 7e-08
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 59 7e-08
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 59 7e-08
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 59 7e-08
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 59 7e-08
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 58 9e-08
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 58 9e-08
UniRef50_A2UBY5 Cluster: Plant-metabolite dehydrogenase; n=1; Ba... 58 9e-08
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 58 9e-08
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 58 9e-08
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 58 1e-07
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 58 1e-07
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 58 2e-07
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 58 2e-07
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 58 2e-07
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 57 2e-07
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 57 2e-07
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 57 2e-07
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 57 2e-07
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 57 2e-07
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 57 2e-07
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 57 3e-07
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 57 3e-07
UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1; ... 57 3e-07
UniRef50_A6BFM9 Cluster: Putative uncharacterized protein; n=1; ... 56 3e-07
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 56 3e-07
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 56 3e-07
UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa... 56 3e-07
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 56 3e-07
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 56 3e-07
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 56 3e-07
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 56 3e-07
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 56 5e-07
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 56 5e-07
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 56 5e-07
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 56 5e-07
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 56 5e-07
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 56 6e-07
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 56 6e-07
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 56 6e-07
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 55 8e-07
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 55 8e-07
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 55 8e-07
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 55 8e-07
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 55 8e-07
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 55 8e-07
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 55 1e-06
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 55 1e-06
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 55 1e-06
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 42 1e-06
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 54 1e-06
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 54 2e-06
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 54 2e-06
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 54 2e-06
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 54 2e-06
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 54 2e-06
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 54 2e-06
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 54 2e-06
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 54 2e-06
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 53 3e-06
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 53 3e-06
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 53 3e-06
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 53 3e-06
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 53 4e-06
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 53 4e-06
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 53 4e-06
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 53 4e-06
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 53 4e-06
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 53 4e-06
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 52 6e-06
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 52 7e-06
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 52 7e-06
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 51 2e-05
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 51 2e-05
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 51 2e-05
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 50 2e-05
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 50 2e-05
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 50 2e-05
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 50 3e-05
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 50 3e-05
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 50 3e-05
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 50 4e-05
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 50 4e-05
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 50 4e-05
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 49 5e-05
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 49 5e-05
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 49 5e-05
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 49 7e-05
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 49 7e-05
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 48 9e-05
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 48 9e-05
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 48 9e-05
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 48 2e-04
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 48 2e-04
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 48 2e-04
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 47 2e-04
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 47 3e-04
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 47 3e-04
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 4e-04
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 46 4e-04
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 46 5e-04
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 5e-04
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 46 7e-04
UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1; ... 46 7e-04
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 45 9e-04
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 45 9e-04
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 45 9e-04
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 45 0.001
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 44 0.002
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 44 0.002
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 44 0.003
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 44 0.003
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 43 0.003
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 43 0.003
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 43 0.005
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 43 0.005
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 42 0.006
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 42 0.008
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 42 0.008
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 42 0.011
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 41 0.014
UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella ve... 41 0.014
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 41 0.014
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 41 0.014
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 41 0.014
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 41 0.019
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 41 0.019
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 41 0.019
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 40 0.024
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 40 0.032
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 40 0.043
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 40 0.043
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 40 0.043
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 40 0.043
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 39 0.057
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 39 0.075
UniRef50_Q14LU7 Cluster: Putative aldo/keto reductase n-terminal... 39 0.075
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 38 0.099
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 38 0.099
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 38 0.17
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 37 0.30
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 36 0.40
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 36 0.53
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 36 0.53
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 36 0.53
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 36 0.53
UniRef50_Q98EU0 Cluster: Oxidoreductase; MocA; n=27; Bacteria|Re... 36 0.70
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 36 0.70
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 36 0.70
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 35 0.92
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 35 1.2
UniRef50_Q0UQ60 Cluster: Putative uncharacterized protein; n=1; ... 35 1.2
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 34 2.1
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 34 2.1
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 33 3.7
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 33 4.9
UniRef50_Q30VP1 Cluster: Putative uncharacterized protein; n=1; ... 32 6.5
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 32 6.5
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 32 8.6
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 116 bits (278), Expect = 4e-25
Identities = 60/157 (38%), Positives = 84/157 (53%), Gaps = 1/157 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF QI R++ KP Q+E N Q +L + + DI AY P G
Sbjct: 124 SIGVSNFNSEQITRLLAECEIKPVTNQVECNPSLNQRKLTEFCKNLDITLTAYSPLGRPN 183
Query: 326 PSKAQPD-APPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
+ PD P P +DD +++ I +KYNKT Q LR+L+++G + +PKS + ER QNI
Sbjct: 184 YYEKDPDNMPKPALDDPKVIEIGKKYNKTSGQVILRYLVDIGTIPIPKSSNSERIRQNID 243
Query: 149 LXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
+ F T EE + F TG RT+P + H PF
Sbjct: 244 IFDFKLTEEEIKIMDGFHTGQRTVPFNLCTSHKYFPF 280
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 113 bits (272), Expect = 2e-24
Identities = 61/159 (38%), Positives = 87/159 (54%), Gaps = 1/159 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + Q+ ++ KP ALQIE + Q +L ++ I+ M Y PFGSL
Sbjct: 174 SIGLSNFNKLQVATVLQECTIKPVALQIEVHPQIIQEDLITYAKDEGIIVMGYSPFGSLV 233
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D P P++DD L S+A+KY KT Q LR+L++ V +PK+V +R +NI +
Sbjct: 234 -KRFGMDLPGPKMDDPVLTSLAKKYEKTPAQIVLRWLVDRKVVPIPKTVSPKRLLENINI 292
Query: 146 XXFSXTPEEXNLXKSFDTGXR-TLPQTKWSKHPDXPFQL 33
F EE F++ R TLP W KHP PF +
Sbjct: 293 FDFKLKEEEIEKINQFNSNTRYTLPSF-WQKHPFYPFDM 330
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 111 bits (266), Expect = 1e-23
Identities = 59/158 (37%), Positives = 91/158 (57%), Gaps = 2/158 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
S+G+SNF + Q++ I++ GL+ KP + Q+E + QP+L K +++DIV AY P G+
Sbjct: 165 SLGVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGT 224
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
+ PP + D L S+ ++YNKT Q LRF I+ G VV+PKS + ER ++N
Sbjct: 225 SRNPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENF 284
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
Q+ FS T EE ++ + R + W HP+ PF
Sbjct: 285 QIFDFSLTEEEMKDIEALNKNVRFVELLMWRDHPEYPF 322
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 99 bits (238), Expect = 3e-20
Identities = 53/158 (33%), Positives = 88/158 (55%), Gaps = 2/158 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
SIG+SNF + Q++ I++ GL+ KP QIE + Q ++ + + DIV +AY GS
Sbjct: 184 SIGVSNFNRRQLEMILNKPGLKYKPVCNQIECHPYLNQKQMLEFCKSKDIVVVAYGVLGS 243
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
K + P ++D L+SI QKY+K+ Q ++R++I+ G V + KS + +R +QN+
Sbjct: 244 PGAGKWVDQSCPILLEDPVLISIGQKYSKSPAQVSMRYMIQRGCVAIAKSFNPDRMKQNL 303
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
++ F + EE + R ++W KHP PF
Sbjct: 304 EVFDFQLSQEEMAAIDGLNKNMRYWSFSEWEKHPQYPF 341
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 99.5 bits (237), Expect = 4e-20
Identities = 53/159 (33%), Positives = 81/159 (50%), Gaps = 1/159 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF Q+ R+++S KP QIE ++ Q +L + I Y PFG+
Sbjct: 161 SIGVSNFNSQQLTRLLESASIKPVMNQIELHINLNQKKLREFCASKSIAVTGYSPFGAPG 220
Query: 326 PSKA-QPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
+ QP + + IA+KYNKT Q LR++I++GA+ +PKS ++R ++NI
Sbjct: 221 RNNVFQPAGADISLQSPVITGIAKKYNKTNAQIVLRYVIDIGAIPIPKSSSEKRIKENID 280
Query: 149 LXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPFQL 33
+ F TPEE D G RT + + PF +
Sbjct: 281 IFDFKLTPEEIAAIDKLDCGFRTCSAIEHKDCKEYPFNI 319
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 98.7 bits (235), Expect = 7e-20
Identities = 52/156 (33%), Positives = 86/156 (55%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF Q +R++ + +P Q+E + Q +L + + + +V AY P
Sbjct: 156 SIGLSNFNAAQTERVLANCRIRPVVNQVECHPGFQQRQLREHAKRHGLVICAYCPLARPQ 215
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P++ P P + DE ++A+KY +T Q LR+L++LG V LPKS +K R E+N ++
Sbjct: 216 PARQWP----PFLYDEHAQNLAKKYGRTTAQICLRYLVQLGVVPLPKSSNKARIEENFRV 271
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
F +P++ + + TG RT+P + S H PF
Sbjct: 272 FDFELSPDDVAGMEQYHTGQRTVPFSGMSGHKYYPF 307
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 98.3 bits (234), Expect = 9e-20
Identities = 58/158 (36%), Positives = 85/158 (53%), Gaps = 2/158 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
+IG+SNF QI+RI++ GL+ KP QIE + Q +L + IV AY P GS
Sbjct: 156 TIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYCHSKGIVVTAYSPLGS 215
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
A+P+ P ++D R+ +IA KYNKT Q +RF I+ VV+PKSV R +N+
Sbjct: 216 PDRPWAKPE-DPSLLEDPRIKAIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPVRIAENL 274
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
++ F + E+ S++ R +KH D PF
Sbjct: 275 KVFDFEVSSEDMATLLSYNRNWRVCALMSCAKHKDYPF 312
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 97.5 bits (232), Expect = 2e-19
Identities = 55/158 (34%), Positives = 81/158 (51%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF QI R++++ KP Q+E +L Q L + +++DI Y P G
Sbjct: 414 SIGVSNFNSEQITRLLEAAKIKPVNNQVEVSLKLNQKALIEFCKKHDITVTGYSPLGRPG 473
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+A DD + + +KY KT Q A RF+ +LGA+ +PKSV K R ++N ++
Sbjct: 474 NRYGITNA----WDDPIIQELVKKYGKTPAQIACRFVSQLGAIPIPKSVTKSRIKENFEI 529
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPFQL 33
FS T EE N +S TG R P + PF +
Sbjct: 530 FDFSLTDEEINSIQSIATGERVAPMEDAKESKYYPFNI 567
Score = 81.0 bits (191), Expect = 1e-14
Identities = 45/129 (34%), Positives = 67/129 (51%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF QI R++ S KP Q+E + Q L + ++++I + P G
Sbjct: 157 SIGLSNFNSEQIARLLSSAKIKPVNNQVEVTMNLNQKPLIEFCKKHEITVTGFSPLGR-- 214
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P D+ ++ +AQKY KT A RF+ +LG +PKSV K R ++N+ +
Sbjct: 215 PGNRH--GIQNLWDEPQIQKLAQKYKKTPANIACRFIHQLGVTPIPKSVTKSRIKENLDI 272
Query: 146 XXFSXTPEE 120
FS TPEE
Sbjct: 273 FDFSLTPEE 281
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 97.5 bits (232), Expect = 2e-19
Identities = 50/159 (31%), Positives = 85/159 (53%), Gaps = 1/159 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF Q++RI+ + KP Q+E + Q L + E DIV A+ PFG
Sbjct: 164 SIGVSNFNSEQLERILANCRVKPVTNQVECSARINQKLLIEFCMERDIVVTAHSPFGRPH 223
Query: 326 PSKAQP-DAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
+ P D P P +D+ +V I +K++K+ Q LR+L++ G V +PKS + +QN++
Sbjct: 224 LFEKNPKDKPKPVLDEPEIVEIGKKFDKSSAQVVLRYLLQNGVVPIPKSTSAQHLKQNLE 283
Query: 149 LXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPFQL 33
+ F + ++ + F+T R + + +H PF +
Sbjct: 284 IFDFELSSDDMAILDGFNTNQRMVRLSLLKEHKYYPFNI 322
>UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,
isoform A; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG6084-PA, isoform A - Tribolium castaneum
Length = 493
Score = 95.5 bits (227), Expect = 6e-19
Identities = 54/158 (34%), Positives = 83/158 (52%), Gaps = 1/158 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIGISNF QI R++ S P QIE + Q +L K + I +Y P GS
Sbjct: 333 SIGISNFNSNQIDRLLKSAKIAPVINQIECHPYLNQSKLRKFCSDRGITVTSYSPLGS-- 390
Query: 326 PSKA-QPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
P++ Q P I+D ++ I KY K+ Q LR+ ++LG VV+PKS ++ R +N+
Sbjct: 391 PARPWQKPGDPYVINDPKIKEIGNKYGKSPAQILLRYNVQLGNVVIPKSSNRNRLVENMS 450
Query: 149 LXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPFQ 36
+ F+ + ++ +FD R PQ + +HP PF+
Sbjct: 451 IFDFTLSEDDMKYIGTFDCNGRICPQAEAREHPFYPFK 488
Score = 62.5 bits (145), Expect = 5e-09
Identities = 38/138 (27%), Positives = 72/138 (52%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF QI+RI+++ +P QI+ + Q +L K N I ++Y P G+
Sbjct: 141 AIGLSNFNSKQIERILENCTIRPQVNQIQCHPYLNQAKLRKYCSNNGIAVISYSPLGA-- 198
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ QP++ + D R+ IA++YNKT + L++ ++LG +V+ + ++
Sbjct: 199 RNNIQPESLDV-LSDCRIKEIARRYNKTPTEIVLKYNVQLGNIVI-----SDMLIESANF 252
Query: 146 XXFSXTPEEXNLXKSFDT 93
F PE+ + +F +
Sbjct: 253 FDFYLAPEDMSYISTFSS 270
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 95.1 bits (226), Expect = 8e-19
Identities = 52/158 (32%), Positives = 84/158 (53%), Gaps = 2/158 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
SIG+SNF + Q++ I++ GL+ KP Q+E +L Q +L + NDIV +AY G+
Sbjct: 162 SIGVSNFNRRQLEMILNKPGLKYKPVCNQVECHLYLNQSKLLAYCKMNDIVLVAYGALGT 221
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
+ P +DD L ++A+KY +T ALR+ ++ G V L KS ++ER +N+
Sbjct: 222 QRYKYCINEDTPVLLDDPVLCAMAKKYKRTPALIALRYQLDRGIVALAKSFNEERIRENM 281
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
Q+ F ++ + D R P + HP+ PF
Sbjct: 282 QVFDFQLASDDMKILDGLDRNLRYFPADMFKAHPNFPF 319
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 94.7 bits (225), Expect = 1e-18
Identities = 51/158 (32%), Positives = 83/158 (52%), Gaps = 2/158 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
SIG+SNF Q++ I++ GL+ KP Q+E ++ Q +L + + DIV + Y GS
Sbjct: 163 SIGVSNFNHKQLELILNMPGLKYKPVCNQVECHVYLNQSKLLEFCKSKDIVLVGYSVLGS 222
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
+ + P ++D L IA+K+N+T Q A+R+ ++ G VVL KS R +QN
Sbjct: 223 SRDERWIEASTPVLLEDPALTEIAKKHNRTPAQVAMRYHLQRGVVVLAKSFTPARIQQNF 282
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
Q+ F E+ + R + ++WS HP P+
Sbjct: 283 QVFDFQLDAEDMRSIDGLNRNMRYIDTSRWSDHPKYPY 320
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 94.7 bits (225), Expect = 1e-18
Identities = 57/159 (35%), Positives = 77/159 (48%), Gaps = 3/159 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF Q QIQRI+D+ KP LQIE ++ QPEL K + N I AY P GS
Sbjct: 158 NIGLSNFNQRQIQRILDNCQIKPANLQIENHIYLQQPELVKFCKANGITVTAYSPLGSKG 217
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
K P +D+ + IA+K K+ Q LR L++ G +PKS + R NI L
Sbjct: 218 IEKLLGREVPDLLDNPVVKDIAEKLGKSPAQVLLRHLLQRGISTIPKSTNPTRLRDNIDL 277
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKW---SKHPDXPF 39
F + D R + +KHP+ PF
Sbjct: 278 FGFEIDDSDMVRLNQLDQNIRICDFGFFPGITKHPEFPF 316
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 93.9 bits (223), Expect = 2e-18
Identities = 56/158 (35%), Positives = 79/158 (50%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF QI+RI+ KP Q+E N Q +L + I AY P G
Sbjct: 164 SIGLSNFNSEQIERILQIATVKPVNNQVEANPGYDQRKLIAFCQARGITVTAYGPMGR-- 221
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P + + +DD +++ I +KY KT Q LR+LI++G + +P S ++ER QNI +
Sbjct: 222 PHRTT-NGNRNALDDPKVLEIGRKYGKTGGQVILRYLIDIGTIPIPYSTNEERMRQNIDV 280
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPFQL 33
F T EE SF + RT+P H PF L
Sbjct: 281 CDFKLTGEEIEYLASFHS-ARTIPFLPLKSHKYYPFDL 317
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 93.1 bits (221), Expect = 3e-18
Identities = 54/158 (34%), Positives = 84/158 (53%), Gaps = 2/158 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
+IGISNF Q++ I++ GL+ KP QIE + Q +L + + IV AY P GS
Sbjct: 156 AIGISNFNHLQVEMILNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS 215
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
A+P+ P ++D R+ +IA K+NKT Q +RF ++ VV+PKSV ER +N
Sbjct: 216 PDRPWAKPE-DPSLLEDPRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENF 274
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
++ F + ++ S++ R + H D PF
Sbjct: 275 KVFDFELSSQDMTTLLSYNRNWRVCALLSCTSHKDYPF 312
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 92.7 bits (220), Expect = 4e-18
Identities = 50/157 (31%), Positives = 77/157 (49%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF Q+QR++D P QIE + Q ++ E I+ AY P GS
Sbjct: 161 NIGVSNFNAKQVQRVLDVARIPPATNQIECHPYLHQSKITTFCAEKGIIVTAYSPLGSPA 220
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D P +DD + +A+K+ K+ Q +R+ I+LG VV+PKSV KER N +
Sbjct: 221 RPWVKAD-DPVLMDDATVGQLAKKHGKSAAQILIRYQIQLGHVVIPKSVTKERIASNFDV 279
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPFQ 36
F ++ + R P++ HP PF+
Sbjct: 280 FSFQLDEDDMKQLAGLERNGRICPESSAFGHPHHPFE 316
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 91.5 bits (217), Expect = 1e-17
Identities = 54/163 (33%), Positives = 90/163 (55%), Gaps = 7/163 (4%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF QI+RI+ + K LQIE ++ Q EL K ++ +I AY P GS
Sbjct: 159 AIGLSNFNISQIKRILKNTKMKISMLQIELHVYFQQKELVKFCKQENIPITAYSPLGSRS 218
Query: 326 PSKA--QPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
K + + + ++ ++ IA+KY K+ Q LR++++ G VV+PKS++ +R ++NI
Sbjct: 219 LIKLLNKTEEISDMLQNDVVMEIAKKYKKSSAQILLRYIVQNGIVVIPKSINPQRIKENI 278
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRT-LPQTKWSK----HPDXPF 39
QL + PE+ + D G + + K+ K HP+ PF
Sbjct: 279 QLFDWEINPEDMKKLYNLDRGESSRICDLKFFKGIETHPEYPF 321
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 90.6 bits (215), Expect = 2e-17
Identities = 52/145 (35%), Positives = 76/145 (52%), Gaps = 4/145 (2%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS-- 333
SIG+SNF Q Q+ I ++ KP LQ+E + Q +L K +E++IV AY P GS
Sbjct: 177 SIGLSNFNQSQVLNIYNNAEIKPSNLQVETHAYLQQKQLRKFCKEHNIVMTAYAPLGSHN 236
Query: 332 --LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQ 159
L + P P ++ + S+A KYNK+ Q LR I+ G V +PKS + +R +
Sbjct: 237 ARLNLHRGTPKELPALVELPLIKSLAAKYNKSPGQILLRHTIQEGLVAIPKSSNAQRQKS 296
Query: 158 NIQLXXFSXTPEEXNLXKSFDTGXR 84
NI + F T EE + D G +
Sbjct: 297 NIDIFDFKLTDEEMKKIDALDKGEK 321
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 90.2 bits (214), Expect = 2e-17
Identities = 50/157 (31%), Positives = 79/157 (50%), Gaps = 1/157 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF QIQR+ D+ KP LQ+E + Q +L + +E IV + Y P G+
Sbjct: 156 SIGLSNFTHSQIQRVWDAAEVKPACLQVELHPYFTQVKLREFCKEKGIVVVGYSPLGNPG 215
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + D P + +E + IA+ + KT Q LR+ ++ G +PKSV +R +N+ +
Sbjct: 216 SAFFRKDGDPNVLTNEVVAGIAKAHGKTPAQIILRWFVDSGLSAIPKSVTPQRISENLAV 275
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP-QTKWSKHPDXPF 39
F T EE + + R + + HP PF
Sbjct: 276 FDFQLTAEEISKIDGINKNWRIVDLSQRDGDHPHCPF 312
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 86.6 bits (205), Expect = 3e-16
Identities = 48/137 (35%), Positives = 70/137 (51%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + R+I P QIE + Q +L E I MAY PFG
Sbjct: 168 SIGVSNFDTALLDRLIAGSNTVPAVNQIEVHPSKTQEKLVADSHERGIEVMAYSPFG-FY 226
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
S+ + P +D + IA+KYNKTV Q +R+L+E + +PKS +++R +NI +
Sbjct: 227 VSRGSHNNPVK--NDRTVADIARKYNKTVNQVLVRYLLERSLIPIPKSTNQQRIRENIDV 284
Query: 146 XXFSXTPEEXNLXKSFD 96
F +PE+ N D
Sbjct: 285 FDFQLSPEDINAIGKLD 301
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 86.2 bits (204), Expect = 4e-16
Identities = 53/158 (33%), Positives = 81/158 (51%), Gaps = 2/158 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
++G+SNF QI+R+++ GL+ KP Q+E + Q +L + I AY P GS
Sbjct: 156 ALGVSNFNHFQIERLLNKPGLKHKPVTNQVECHPYLTQEKLTQYCHSKGITITAYSPLGS 215
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
A+P+ P ++ ++ IA K+ KT Q +RF IE VV+PKSV R ++NI
Sbjct: 216 PDRPSAKPE-DPLLLEIPKIKEIAAKHKKTAAQVLIRFHIERNVVVIPKSVTPSRIQENI 274
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
Q+ F + E+ SF+ R S + D PF
Sbjct: 275 QVFDFQLSEEDMAAILSFNRNWRACGLFAASHNEDFPF 312
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 86.2 bits (204), Expect = 4e-16
Identities = 51/153 (33%), Positives = 77/153 (50%), Gaps = 2/153 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + Q+ I+ G +P Q+E ++ Q +L K I+ MAY P G
Sbjct: 150 SIGVSNFNEEQLMEIVTHGSIRPVVNQVECSIGFHQVKLRKFCNREGILIMAYSPLGKPK 209
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P K +D L +A+KY ++ Q +LRFLIE+G + +PKS +R ++N+ +
Sbjct: 210 PGKKHVF-----LDSSDLNKMAEKYGRSPAQISLRFLIEIGTIPIPKSSKTDRMKENLDV 264
Query: 146 XXFSXTPEEXNLXKSFDTGXR--TLPQTKWSKH 54
F + +SF R TL K SKH
Sbjct: 265 LSFKLEETDVQALESFVKQQRSMTLDWLKSSKH 297
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 85.8 bits (203), Expect = 5e-16
Identities = 46/156 (29%), Positives = 76/156 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++R+I+ +P LQ+E + Q +L + +E+++ AY P G+
Sbjct: 114 AIGLSNFSMKMMKRVIEKATIQPANLQVELHPLLTQEKLIEFCKEHNMTVTAYSPLGAPD 173
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D P ++D + IA K K+ Q +RF +E G + +PKSV R + N +
Sbjct: 174 RPWVKDD-DPKLMEDPIVTGIATKKGKSPAQILIRFCLERGIICIPKSVTPSRIQANFEA 232
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
F PE+ + + G R W HP PF
Sbjct: 233 LNFELDPEDLKTLLAMNIGYRGC-LLDWVNHPQHPF 267
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 84.6 bits (200), Expect = 1e-15
Identities = 47/129 (36%), Positives = 75/129 (58%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF QI++I+ KP Q+E N+ Q +L + + +IV AY P G
Sbjct: 150 SIGLSNFTIPQIEKIMKMCRIKPVINQVELNVYLQQNKLREVCKSYNIVVEAYRPIGGKP 209
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+++ + +DDE +VS+A+KYNKT Q LR+L++ G + +PKS + R QN Q+
Sbjct: 210 ANESDKNC----LDDEVVVSLAKKYNKTTAQICLRWLVQNGIIAVPKSTNPNRLLQNYQV 265
Query: 146 XXFSXTPEE 120
+S + E+
Sbjct: 266 FEWSLSNED 274
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 84.6 bits (200), Expect = 1e-15
Identities = 50/158 (31%), Positives = 79/158 (50%), Gaps = 2/158 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
SIG+SNF Q++RI++ GL+ KP Q+E +L Q +L DIV +AY G+
Sbjct: 162 SIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGT 221
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
+ P ++D L +A+K ++ ALR+LI+ G V L +S + +N+
Sbjct: 222 QRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENL 281
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPF 39
Q+ F +PE+ + R LP HP+ PF
Sbjct: 282 QVFGFQLSPEDMKTLDGLNKNFRYLPAEFLVDHPEYPF 319
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 82.2 bits (194), Expect = 6e-15
Identities = 51/158 (32%), Positives = 76/158 (48%), Gaps = 3/158 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
++G+SNF Q+Q + D+ KP Q+E ++ Q EL ++ + AY P GS
Sbjct: 159 ALGVSNFSCNQLQALYDAAEVKPANQQVECHIYWPQQELRALCKKLGVTVTAYAPLGSPG 218
Query: 326 PSKAQPDAPPPRIDD--ERLVS-IAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
A+PD P D E +V +A KY+KT Q +R L + G +PKSV +R +N
Sbjct: 219 RKAARPDGVWPEGDPLLEPIVKQLAAKYHKTAAQILIRHLTQHGISTIPKSVSPDRIVEN 278
Query: 155 IQLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXP 42
I F + E+ + S +T R KHP P
Sbjct: 279 ISTFDFKLSDEDMHTLNSIETRTRLFIADFAVKHPFFP 316
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 81.8 bits (193), Expect = 8e-15
Identities = 53/144 (36%), Positives = 70/144 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
S+G+SNF I +I ++G P QIE + Q EL R + I ++ PF
Sbjct: 139 SVGVSNFLSEHIDKIKEAGFPLPSVNQIELHPWLQQRELVLSCRNDGIQIESWGPFARFS 198
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
DA P L A++Y KT Q LR+ I+ G VV PK+VH ER QNI +
Sbjct: 199 KDL---DAFP------ELTRPAKQYGKTPAQVILRWHIQKGYVVFPKTVHAERLRQNIDI 249
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP 75
F TP+E + S D G RT P
Sbjct: 250 FDFDLTPDEISGIDSLDAGFRTGP 273
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 81.8 bits (193), Expect = 8e-15
Identities = 49/163 (30%), Positives = 81/163 (49%), Gaps = 7/163 (4%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS-- 333
+IG+SNF Q+QRII +P LQ+E ++ Q L ++DIV A+ P G
Sbjct: 170 NIGLSNFNADQVQRIIKGCQVRPAVLQVEVHVYMQQGALRAFCAQHDIVVCAFCPLGGPF 229
Query: 332 -LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
L ++P ++D +++ +A ++KT Q LR+L ++ + +PKS + R QN
Sbjct: 230 RLIRKASRPGEVKLLLEDPQVLDVATAHHKTPAQVLLRYLHQINVIPIPKSANPTRLFQN 289
Query: 155 IQLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSK----HPDXPF 39
Q+ F T E + D G T++ + HP+ PF
Sbjct: 290 TQIFDFELTSAEMSRLAGLDRGHEGRIFTEFRRGDHTHPEFPF 332
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 80.2 bits (189), Expect = 2e-14
Identities = 49/160 (30%), Positives = 77/160 (48%), Gaps = 3/160 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF QI R++ P Q+E + Q +L + +I A+ PFGS
Sbjct: 130 SIGVSNFTMEQIDRLLSVAKIPPAVNQVELHPYLVQSDLIDYCKSKNIALTAHSPFGSPG 189
Query: 326 -PSKAQPDAPPPR--IDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
P + Q P ++D +V +A+K+ +T Q LR+ I+ V+PKSV +N
Sbjct: 190 RPLEFQTGDEDPMGLLEDPVVVDVARKHRRTPAQVLLRYHIQQDIAVIPKSVKPHHILEN 249
Query: 155 IQLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPFQ 36
++ F+ E+ N KS + G R T+ H PF+
Sbjct: 250 TKIFDFTLDEEDMNALKSLNRGWRACIITELEAHYFYPFK 289
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 79.4 bits (187), Expect = 4e-14
Identities = 44/147 (29%), Positives = 68/147 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
S+G+SNF Q+ ++ P LQ+E + Q EL RE +V AY P G
Sbjct: 158 SLGLSNFNSKQLDDVLQHSTVPPSVLQVESHPFLPQVELLNFCRERSVVVSAYSPLGC-G 216
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ P DD L+ IAQ+ K++ Q A+RF ++ G V+PKS ++NI +
Sbjct: 217 DRAWKLSGEPSIFDDPGLLKIAQRLRKSIAQVAIRFQVQRGIPVIPKSATPSHIQENINV 276
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTK 66
F + ++ L S +P K
Sbjct: 277 FDFELSEDDMALLSSLPRRRILVPPKK 303
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 79.0 bits (186), Expect = 6e-14
Identities = 50/157 (31%), Positives = 78/157 (49%), Gaps = 1/157 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG++NF Q++++ GL KP LQ+E N Q E+ + RE I+ A+ G+
Sbjct: 163 SIGLANFNIGQVEQVWTKGLIKPAVLQVEMNPFLDQEEIRQFCREKGIILTAFMLTGNPG 222
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + P + +E L SIA+ + K+V Q +R+ I+L L KS +R QNI +
Sbjct: 223 SALYRKHEDPNLLYNETLQSIAKGHGKSVVQVLVRWAIDLRTTALVKSSESKRIRQNINI 282
Query: 146 XXFSXTPEEXNLXKSFDTGXRTL-PQTKWSKHPDXPF 39
F T +E K+ + R L P HP P+
Sbjct: 283 FKFRLTSQEIARIKALNIDFRILNPLLGNYDHPYFPW 319
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 78.6 bits (185), Expect = 8e-14
Identities = 47/158 (29%), Positives = 73/158 (46%), Gaps = 1/158 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + Q+ R++ KP LQIE + Q L +N I AY GS
Sbjct: 159 AIGVSNFNEQQMNRLLSVAKLKPVVLQIECHPYLSQKPLITLCYDNAIAVTAYSCLGSGH 218
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI-Q 150
+P A P + +++IA+KY +T Q LRF + G +V+P+SV K+ N +
Sbjct: 219 TPYEKPGA-YPLLQHPTILAIAEKYERTAAQVLLRFQTQSGIIVIPRSVSKQHMLDNFKR 277
Query: 149 LXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPFQ 36
+ F ++ D R + HP PF+
Sbjct: 278 IWDFELAVDDIQAINELDCNGRFMTMKAAYGHPHHPFE 315
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 77.0 bits (181), Expect = 2e-13
Identities = 47/158 (29%), Positives = 74/158 (46%), Gaps = 1/158 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + QI R++ KP LQIE + Q L +N I AY GS
Sbjct: 158 AIGVSNFNEKQINRLLCLAKLKPVMLQIECHPYLRQKSLITLCYDNAIGVTAYSSLGSGH 217
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI-Q 150
+P + P + + +VS+A+KY +T Q LR+ + G +V+P+SV K+ N +
Sbjct: 218 TPYEKPGSYP-LLQNPIIVSVAEKYGRTPAQVLLRYQTQSGIIVIPRSVSKQHMHDNFKR 276
Query: 149 LXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPFQ 36
+ F ++ D R + HP PF+
Sbjct: 277 IWDFQLAIDDVKAIDGLDCNGRFMTMKAAYGHPHHPFE 314
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 76.6 bits (180), Expect = 3e-13
Identities = 49/165 (29%), Positives = 77/165 (46%), Gaps = 8/165 (4%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + Q+ R++ + +P QIE ++ Q +L + +I AY P GS
Sbjct: 160 SIGVSNFSKDQVARLLKNCKIRPANNQIEHHVYLQQRDLVDFCKSENITVTAYSPLGSKG 219
Query: 326 PSKAQPDAP-----PPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXE 162
+K A P +D + IA + KT Q LR++I+ G +PKS + R +
Sbjct: 220 IAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPAQVLLRWIIDTGVSAIPKSTNPARLK 279
Query: 161 QNIQLXXFSXTPEEXNLXKSFDTGXRTLPQTKW---SKHPDXPFQ 36
QN+ + F T EE S D R + +HP+ F+
Sbjct: 280 QNLDVFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHPEFTFK 324
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 75.8 bits (178), Expect = 5e-13
Identities = 39/129 (30%), Positives = 69/129 (53%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
++G+SNF QI I+ +P LQ+E + Q EL + + AY P GS
Sbjct: 158 ALGLSNFNSRQIDDILSVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSD 217
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ PD P +++ ++++A+KY ++ Q LR+ ++ + +PKS+ R QNI++
Sbjct: 218 RAWRDPDEPV-LLEEPVVLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKV 276
Query: 146 XXFSXTPEE 120
F+ +PEE
Sbjct: 277 FDFTFSPEE 285
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 74.9 bits (176), Expect = 9e-13
Identities = 45/155 (29%), Positives = 78/155 (50%), Gaps = 2/155 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+ NF ++ ++D KP QIE N QP++ K RENDI A+ P G+
Sbjct: 145 AIGVCNFNVERMTDLLDHAKIKPAINQIEFNPLIHQPKIVKFCRENDIQLEAWSPLGN-- 202
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ ++ + IA ++ K+ Q LR+ I+ G +VL K+ H +R ++N ++
Sbjct: 203 ---------GRLLSNDVIKQIADEHQKSPAQVILRWEIQQGFIVLTKTTHPQRMKENAEI 253
Query: 146 XXFSXTPEEXNLXKSFDTGXRTL--PQTKWSKHPD 48
F+ +P+E D ++ + KWS +PD
Sbjct: 254 FDFTLSPDEMKQIDKLDQEKHSIWYDKFKWSGNPD 288
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 74.1 bits (174), Expect = 2e-12
Identities = 47/147 (31%), Positives = 75/147 (51%), Gaps = 4/147 (2%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXA-LQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS- 333
+IG+SNF QIQR++D + P A +Q+E + Q EL + ++ I AY P GS
Sbjct: 160 AIGVSNFTVAQIQRVLDLPPKYPIANVQVECHPFLAQNELIEFCKKQGITVTAYSPLGSP 219
Query: 332 --LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQ 159
+ +A D P ++D + +IA+K + Q +R+ ++ G VLPKSV R +Q
Sbjct: 220 ERVLQKRATTD--PLLMEDPVVCAIAKKKGVSPAQVLIRYQLQRGVAVLPKSVMPSRIQQ 277
Query: 158 NIQLXXFSXTPEEXNLXKSFDTGXRTL 78
N + F + EE + + R L
Sbjct: 278 NFEALNFELSKEEFQALVNLNKNYRLL 304
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 74.1 bits (174), Expect = 2e-12
Identities = 48/137 (35%), Positives = 72/137 (52%), Gaps = 2/137 (1%)
Frame = -2
Query: 443 KPXALQI-EXNLXXXQPELFKXXRENDIVXMAYXPFGSLX-PSKAQPDAPPPRIDDERLV 270
KP Q+ E + Q +L + + DIV +AY GS P PD P +++ L
Sbjct: 166 KPTCNQVVECHPYLNQSKLLEFCKSKDIVLVAYSALGSQRDPQWVDPDCPH-LLEEPILK 224
Query: 269 SIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLXXFSXTPEEXNLXKSFDTG 90
SIA+K++++ Q ALR+ ++ G VVL KS +ER ++N Q+ F TPE+ K+ D
Sbjct: 225 SIAKKHSRSPGQVALRYQLQRGVVVLAKSFSQERIKENFQIFDFELTPED---MKAIDGL 281
Query: 89 XRTLPQTKWSKHPDXPF 39
R L + HP PF
Sbjct: 282 NRNLRYDNAANHPYFPF 298
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 74.1 bits (174), Expect = 2e-12
Identities = 39/129 (30%), Positives = 69/129 (53%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++Q ++ +P Q+E NL Q +L + +EN I+ A+ P
Sbjct: 163 AIGVSNFSVKKLQNLLSVATIRPVVDQVEMNLAWQQKKLREFCKENGIIVTAFSPL---- 218
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
K P ++++ L IA+ + K++ Q +LR+L E G +PKS KER QN+ +
Sbjct: 219 -RKGASRGPNEVMENDVLKEIAEAHGKSIAQVSLRWLYEQGVTFVPKSYDKERMNQNLHI 277
Query: 146 XXFSXTPEE 120
++ T ++
Sbjct: 278 FDWALTEQD 286
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 73.7 bits (173), Expect = 2e-12
Identities = 49/168 (29%), Positives = 87/168 (51%), Gaps = 12/168 (7%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS-- 333
+IG+SNF + QI RI++ A Q+E +L Q + ++++I+ AY GS
Sbjct: 149 AIGVSNFNESQIVRIMNIQKVPIHASQLELHLYLPQKAHRELCKKHNILITAYATLGSPG 208
Query: 332 ---LXPSKAQP-----DAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVH 177
+ S +P ++D+ + ++AQKY+KT Q LR +E+G +V+PK+ +
Sbjct: 209 RMSVVGSNGRPLFESTQNSENEMNDKHVKALAQKYSKTPAQILLRATVEMGIIVIPKTTN 268
Query: 176 KERXEQNIQLXXFSXTPEEXNLXKSFD--TGXRTLPQTKWSKHPDXPF 39
ER ++NI + F+ + E NL ++ + R + HP+ PF
Sbjct: 269 PERMKENINIFDFNISNAEVNLLEAHERTKQERLFWWPNVADHPEDPF 316
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 73.3 bits (172), Expect = 3e-12
Identities = 42/121 (34%), Positives = 67/121 (55%), Gaps = 2/121 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
++GISNF QI+++++ GL+ KP Q+E + Q +L + I AY P GS
Sbjct: 156 ALGISNFNHFQIEKLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITITAYSPLGS 215
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
A+P+ P +++ ++ IA K+ KT Q +RF I+ +V+PKSV R +NI
Sbjct: 216 PDRPWAKPE-DPSLLEEPKIKEIAAKHKKTTAQVLIRFHIQRNVIVIPKSVTPARIVENI 274
Query: 152 Q 150
Q
Sbjct: 275 Q 275
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 73.3 bits (172), Expect = 3e-12
Identities = 42/150 (28%), Positives = 78/150 (52%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF +++ ++ +P Q E ++ +P+L + ++++I Y P G+
Sbjct: 148 SIGVSNFNIKKLEELLAIAKIQPAVNQFEFHIYYQRPKLHQFCKKHNIHITGYCPLGNPG 207
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
S P AP ++E + +IA+K+NK Q ++F I G V+PKSVH+ER ++N ++
Sbjct: 208 ISSGVP-AP---FENEVVKAIAKKHNKKAAQICIKFSIASGHSVIPKSVHEERIKENGEV 263
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWSK 57
F E+ + D + + + K
Sbjct: 264 FDFELDEEDMEKLRGLDKNIKVCDMSFYFK 293
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 72.9 bits (171), Expect = 4e-12
Identities = 51/165 (30%), Positives = 75/165 (45%), Gaps = 9/165 (5%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + Q+ + + KP LQIE Q + + E +I A+ GS
Sbjct: 181 SIGLSNFNKSQLLNVYEHAEIKPSNLQIELQAYNQQRPMRELCAERNITVTAFSTLGSPG 240
Query: 326 PS---KAQPDAPPPRIDDERLVS-IAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQ 159
S K + P + D +V IA+ +N+T Q LR ++ G +VLPKS + R +Q
Sbjct: 241 SSPDKKTRYIKSLPTLFDHPIVKKIAEAHNRTSAQVLLRHAVQNGIIVLPKSTNPGRIKQ 300
Query: 158 NIQLXXFSXTPEEXNLXKSFDTGXR-----TLPQTKWSKHPDXPF 39
NI + F+ T +E D G + KHP PF
Sbjct: 301 NIGIFDFALTEDEMQAMNGLDKGEKGRIFHFFIDKGVEKHPQYPF 345
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 71.3 bits (167), Expect = 1e-11
Identities = 45/146 (30%), Positives = 71/146 (48%), Gaps = 5/146 (3%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + QI I+ KP LQ+E + Q L + ++N I+ Y P GS
Sbjct: 184 SIGLSNFNETQITNILKEAKIKPSNLQVEVHAYHQQKPLIEFCQKNGIIVTGYAPLGSPG 243
Query: 326 PSK----AQPDAPPPRIDDERLVS-IAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXE 162
K Q + P + +V+ IA+K+ K+V Q L L++ G V+ S + +
Sbjct: 244 ARKELHPGQMEEEFPDVFKLPVVNEIAKKHGKSVVQILLHHLVQKGIAVIFSSKNPNHLK 303
Query: 161 QNIQLXXFSXTPEEXNLXKSFDTGXR 84
+NI++ F T +E + D G R
Sbjct: 304 ENIEIFDFELTEDEMKSLDALDKGER 329
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 71.3 bits (167), Expect = 1e-11
Identities = 41/129 (31%), Positives = 66/129 (51%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + Q++++ + KP QIE + Q +L + +NDIV Y P G
Sbjct: 134 AIGVSNFSEDQLKQVFEMATVKPMINQIERHPYKVQADLGQFDTDNDIVNEGYSPIGHGH 193
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
++D + +A+KY K+ Q LR+ I+ G VV PKS R ++N ++
Sbjct: 194 LI----------LEDPVITKLAEKYGKSPAQIVLRWQIDTGFVVFPKSSKPARVKENFEI 243
Query: 146 XXFSXTPEE 120
FS T +E
Sbjct: 244 SGFSLTADE 252
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 71.3 bits (167), Expect = 1e-11
Identities = 49/131 (37%), Positives = 68/131 (51%), Gaps = 2/131 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIID-SGLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
SIG+SNF + IQ + D GL+ KP QIE + + +L + IV AY P +
Sbjct: 145 SIGVSNFGKHHIQELYDWEGLKYKPIVNQIELSPWLMRKDLVDYCQNLGIVLEAYCPLTT 204
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
+++D LV +A+KYNKT Q LR+ I+ G VV+PKS+ ER QN
Sbjct: 205 -----------GAKLNDPTLVKLAKKYNKTPAQVLLRWNIDRGVVVIPKSLKPERLPQNF 253
Query: 152 QLXXFSXTPEE 120
L F T E+
Sbjct: 254 DLFDFKLTDED 264
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 71.3 bits (167), Expect = 1e-11
Identities = 44/149 (29%), Positives = 72/149 (48%), Gaps = 1/149 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SN+ + + KP Q E + + L K ++ ++ A+ P G
Sbjct: 157 SIGLSNYELFLTRDCLAYSKIKPAVSQFETHPYFQRDSLVKFCMKHGVLPTAHTPLGGAA 216
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+K + P +DD L +A+KY K+V Q LR+ I+ V+PKS +R ++N+++
Sbjct: 217 ANKDMFGSVSP-LDDPVLNDVAKKYGKSVAQICLRWGIQRKTAVIPKSSKIQRLKENLEV 275
Query: 146 XXFSXTPEEXNLXKSFDTGXRT-LPQTKW 63
F + E+ L S D RT LP W
Sbjct: 276 LEFQLSDEDMQLIYSIDRKYRTSLPSKTW 304
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 70.1 bits (164), Expect = 3e-11
Identities = 44/144 (30%), Positives = 68/144 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG SNF ++RII E P QIE N QPE+ + + +V A+ P G+
Sbjct: 136 SIGTSNFNADHLERIIAETGEAPVLNQIELNPMLQQPEMRAVHKAHGVVTQAWTPLGNAR 195
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+A+P + + K+ Q LR+ ++LG V+P+SV R +N+ +
Sbjct: 196 SFEAEP-----------ITKAVARTGKSPVQVILRWHVQLGNAVIPRSVKAHRQAENLDV 244
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP 75
F+ T E + + D G RT P
Sbjct: 245 FDFTLTEAEMSEIATLDMGLRTGP 268
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 70.1 bits (164), Expect = 3e-11
Identities = 40/119 (33%), Positives = 61/119 (51%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + +I+ ++ + P QIE + Q +L + + IV Y P G+
Sbjct: 156 SIGVSNFTREKIEELLKTAKITPAVNQIEAHPFLQQRDLLEWSTQKGIVVAGYSPLGNNI 215
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
+ P +DD ++ A+K NKT Q + + ++ G VVLPKSV ER E N Q
Sbjct: 216 YNI------PRAVDDPLVIETAKKLNKTPAQVLISWAVQRGTVVLPKSVTPERIESNFQ 268
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 69.7 bits (163), Expect = 3e-11
Identities = 41/149 (27%), Positives = 67/149 (44%), Gaps = 1/149 (0%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS-LX 327
IG+SNF +Q I+D+G +P Q+E + QPEL ++I AY P GS
Sbjct: 155 IGVSNFSVPNLQMILDAGEVRPEMNQVEMHPYLPQPELVSFAEAHNIPITAYSPLGSGDR 214
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P + D P + + + IA ++ + Q L++ + G V+PKS + N+
Sbjct: 215 PDAMKADDEPTLMANPTINDIADRHGVSPAQVLLQWGVARGTAVIPKSTTPAHIKDNLAA 274
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWS 60
+ +E S D+ R L W+
Sbjct: 275 ADLDLSADELETIDSLDSKYRYLAGAAWT 303
>UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1;
Helicobacter hepaticus|Rep: Putative uncharacterized
protein - Helicobacter hepaticus
Length = 270
Score = 69.3 bits (162), Expect = 5e-11
Identities = 45/147 (30%), Positives = 68/147 (46%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IGISNF + S P Q E +L Q L + + + ++ PF +
Sbjct: 133 IGISNFGAKAYSEFVKSCEVIPAINQCETHLLLQQKPLREAMKSKKTLLQSWSPFIAGKG 192
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
S +++ L SIAQKYNKT Q LRFLIE G V+PK+ + R ++N+ +
Sbjct: 193 SI---------LENPTLKSIAQKYNKTPAQVVLRFLIEQGISVIPKTSKRARMQENLNVF 243
Query: 143 XFSXTPEEXNLXKSFDTGXRTLPQTKW 63
FS + ++ + K DT T +
Sbjct: 244 DFSLSAQDTQILKELDTNKSAFSWTNY 270
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 69.3 bits (162), Expect = 5e-11
Identities = 42/139 (30%), Positives = 68/139 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + ++ KP Q+E + QPE + ++ A+ P G
Sbjct: 141 AIGVSNFYPHVLANFCETVRVKPMVNQVELHPYFAQPEALATMKYYNVQPEAWAPLGG-- 198
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ +P ++ L SIA + K++ Q LR+ I+ G VV+PKS H++R E+N +
Sbjct: 199 -GRHKP------FENNLLQSIADAHQKSISQVILRWNIQRGVVVIPKSTHQQRIEENFAI 251
Query: 146 XXFSXTPEEXNLXKSFDTG 90
FS T +E S D G
Sbjct: 252 WDFSLTEKEMAQISSLDLG 270
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 68.9 bits (161), Expect = 6e-11
Identities = 42/142 (29%), Positives = 70/142 (49%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SN+ + ++ + P Q+E + Q L + +++ I AY P
Sbjct: 140 AIGVSNYTIIHLTELLKNSQITPAVNQVEFHPFLNQIHLLEYCKKHKIQLEAYSPL---- 195
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A +I+D + IAQKY+KT Q +R+ IE VV+PKS+ KER +N ++
Sbjct: 196 -------AHGQKIEDPTIAKIAQKYDKTPAQILIRWAIEQKIVVIPKSIKKERIIENSKV 248
Query: 146 XXFSXTPEEXNLXKSFDTGXRT 81
F+ + E+ + S D RT
Sbjct: 249 FDFAISEEDMKILNSLDEDFRT 270
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 68.5 bits (160), Expect = 8e-11
Identities = 44/148 (29%), Positives = 67/148 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + ++ KP A Q+E + QPEL K +++I AY P G+
Sbjct: 154 SIGLSNFNVQGLMEVLSYARIKPAANQVELHPFLSQPELKKFCDKHNIHLTAYSPLGN-- 211
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+D+E + +IA+KYNKT+P ++ I+ V+PKS R +N L
Sbjct: 212 ---------GAFVDNEEVGAIAKKYNKTIPNVLCKWAIQKNFSVIPKSSTPSRVAENFDL 262
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKW 63
F + D RT K+
Sbjct: 263 FNFEIEEADMLFLDKMDKNLRTCDPAKF 290
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 68.5 bits (160), Expect = 8e-11
Identities = 39/141 (27%), Positives = 68/141 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + ++ + P Q+E + Q L E +I A+ P G
Sbjct: 136 AIGVSNFEPHHLDDLLANCTVPPMVNQVEMHPHFQQKALRAYCAEKNIAVTAWRPLGK-- 193
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + +LV +A+K+ ++ Q +R+LI+LG + +PKS H+ER +QN +
Sbjct: 194 ---------GALLTEPQLVELAEKHKRSAAQVIIRWLIQLGVIAIPKSSHEERIKQNFDV 244
Query: 146 XXFSXTPEEXNLXKSFDTGXR 84
F +PE+ +S D R
Sbjct: 245 FDFELSPEDMRRIESMDRNSR 265
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 68.1 bits (159), Expect = 1e-10
Identities = 39/129 (30%), Positives = 65/129 (50%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + QI ++ P QIE ++ Q + K ++ +I+ M Y P G
Sbjct: 161 SIGVSNFNEHQINALLSDASIVPAVNQIECSIGFNQRPMRKFCQQQNILVMGYTPLGK-- 218
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P + + RL IA +KT Q +LR+LI+ G V + KS ++R ++N+ +
Sbjct: 219 -------QKLPFLQNNRLKEIALSVDKTTAQVSLRYLIDEGVVPIVKSTDRKRQQENLDI 271
Query: 146 XXFSXTPEE 120
F T ++
Sbjct: 272 FDFKLTKQQ 280
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 68.1 bits (159), Expect = 1e-10
Identities = 47/146 (32%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIID-SGLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
SIG+SN+ Q + ++ GL+ +P Q+E N + EL + REN+I A+ P
Sbjct: 148 SIGVSNYGQQHLSELLGWEGLKIRPVVNQVEINPWLCRQELVQYCRENNIAVQAFSP--- 204
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
L K R+DD L +A +Y+K V Q +R+ I++G +VLPK+ KER N
Sbjct: 205 LMRGK--------RLDDPILQKVAHQYDKGVAQILVRWSIQMGFIVLPKAAKKERLAPNF 256
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLP 75
+ F + E + D T+P
Sbjct: 257 DIWDFELSAETMSELTHSDDYFVTVP 282
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 67.7 bits (158), Expect = 1e-10
Identities = 41/119 (34%), Positives = 59/119 (49%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIGISNF Q +I ++ + P QIE + QP L K +E +I+ +AY P G+
Sbjct: 156 SIGISNFTQDKIDDLLKTAKIPPAVNQIEAHPYLQQPGLHKYLKEKNILSVAYSPLGNNI 215
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
+ P +DD + +IA K K + + ++ G VLPKSV R E N Q
Sbjct: 216 YN------APRVVDDPDVKAIADKLGKDPAALLISWAVQRGTAVLPKSVTPSRIESNFQ 268
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 67.3 bits (157), Expect = 2e-10
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 4/148 (2%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
+IGISNF + QI+ +++ GL+ KP QIE + Q +L R I A+ GS
Sbjct: 180 AIGISNFNKDQIEAVLNKPGLKHKPATNQIECHPHLNQEKLIHFCRSRGISVTAFACLGS 239
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
S A D P +DD ++ +IA+K T Q ++F I+ + KSV R ++NI
Sbjct: 240 ADRSWASADEPS-FLDDPQINAIARKNQMTPAQVLIKFQIQRNITAVVKSVSPHRIKENI 298
Query: 152 QLXXFSXTPEEXNLXKSFDTGXR--TLP 75
+ + + ++ SF++ R TLP
Sbjct: 299 KAFDYELSDDDMKTLMSFNSNWRGYTLP 326
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 67.3 bits (157), Expect = 2e-10
Identities = 40/145 (27%), Positives = 70/145 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + R++ P QIE + Q L + E+ I+ A+ P G +
Sbjct: 151 AIGVSNFMPEHLTRLLTETSIVPAVNQIEVHPYFQQRALQRLHAEHGILTQAWSPIGGIT 210
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + ++D L+ IAQ++ K+ Q LR+ ++ G V+PKS R +N +
Sbjct: 211 FYRGGEKST---LEDPVLLEIAQQHGKSAAQVMLRWHLQEGRSVIPKSTKPARIAENFDV 267
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQ 72
F + E+ + DTG R+ P+
Sbjct: 268 FDFELSGEQIAAIDALDTGVRSGPE 292
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 66.9 bits (156), Expect = 2e-10
Identities = 41/136 (30%), Positives = 69/136 (50%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + ++ + P QI N + E+ R++DI+ AY P G+
Sbjct: 147 AIGVSNFRPKHLDALLKTAKVVPAVNQIFLNPSDMEDEVVAYNRKHDILSEAYSPLGT-- 204
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + P L ++A KY+K+V Q LR+ ++ G + LPKSVH +R EQN +L
Sbjct: 205 ---GKIFSIP------ELKTLADKYDKSVAQVVLRWSLQHGFLPLPKSVHADRIEQNTEL 255
Query: 146 XXFSXTPEEXNLXKSF 99
F + ++ + F
Sbjct: 256 FDFELSDDDMKVIDGF 271
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 66.9 bits (156), Expect = 2e-10
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 5/144 (3%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + + I +GL P A QIE + +P+L ++ I +AY L
Sbjct: 179 SIGVSNFNESHLNEIKAAGLPMPDANQIELHPWSQKPDLLAYMDQHAIAPIAYSSLVPLS 238
Query: 326 PSKAQPDAPPPRIDDERLVS-----IAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXE 162
+ + + D+ + +A+KY + Q LR+ ++ G VLPKS++ +R
Sbjct: 239 TWRTKEGQASAKTDEMKAAGTTFRDMAEKYGVSEAQLLLRWGVQNGYAVLPKSMNPDRMR 298
Query: 161 QNIQLXXFSXTPEEXNLXKSFDTG 90
QNI L FS + + D G
Sbjct: 299 QNIDLFSFSIDDTDMAKMATMDQG 322
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 66.5 bits (155), Expect = 3e-10
Identities = 44/137 (32%), Positives = 64/137 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIGISNF ++ + + KP ALQ+E + Q EL + + ++ P G
Sbjct: 130 SIGISNFDGERLVDLFNFADIKPSALQVETHPYHQQKELQEFLKPYGTKIESWYPLGH-- 187
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+D+ RL IAQKYNKTV Q LR+ I+ G +V P+S E +NI +
Sbjct: 188 -------GDQRLLDESRLKKIAQKYNKTVAQIILRWHIQEGIIVFPRSTRVEHLAENINI 240
Query: 146 XXFSXTPEEXNLXKSFD 96
F + E + D
Sbjct: 241 FDFELSCTEIKEIRKLD 257
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 66.5 bits (155), Expect = 3e-10
Identities = 43/131 (32%), Positives = 65/131 (49%), Gaps = 2/131 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXN--LXXXQPELFKXXRENDIVXMAYXPFGS 333
+IG+SNF +QRI+ KP QIE + L P ++K +E+DI+ AY P G
Sbjct: 153 NIGVSNFAVEDLQRILKVAEVKPQVNQIEFSPFLQNQTPGIYKFCQEHDILVEAYSPLGP 212
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
L AQ D+ P E + +++KY K+ Q LR++ + G + + S +R
Sbjct: 213 LQKKTAQDDSQP---FFEYVKELSEKYIKSEAQIILRWVTKRGVLPVTTSSKPQRISDAQ 269
Query: 152 QLXXFSXTPEE 120
L F T EE
Sbjct: 270 NLFSFDLTAEE 280
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 66.1 bits (154), Expect = 4e-10
Identities = 45/141 (31%), Positives = 69/141 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIGISNF + ++I+ + P A+QIE + Q EL + + I ++Y GS
Sbjct: 156 SIGISNFGKANTEKILGTCRICPAAIQIELHPYLNQKELVEFMKSKGIQVISYSSLGSAP 215
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
S A+ DD+ + +IA+KY Q L ++ G V+PKS KE +NI L
Sbjct: 216 GSSAKVR------DDKTIKAIAKKYGCAPSQIILSYITAQGICVIPKSRSKEHLRENIDL 269
Query: 146 XXFSXTPEEXNLXKSFDTGXR 84
S E+ + + +TG R
Sbjct: 270 KELSR--EDISAIDALNTGHR 288
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 65.7 bits (153), Expect = 6e-10
Identities = 41/142 (28%), Positives = 65/142 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SN+ ++ + E P Q+E + Q L +E+DIV A+ P G
Sbjct: 138 SIGVSNYTIAHLELLATKAKEMPVVNQVEYHPYLNQQALADYDQEHDIVTEAWSPLGRRV 197
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+DD L +A +NK+V Q LR+ ++ V +PKS H ER ++N +
Sbjct: 198 V-----------LDDPMLAKMAAHHNKSVAQVILRWELQHQLVTIPKSTHPERIQENANI 246
Query: 146 XXFSXTPEEXNLXKSFDTGXRT 81
FS +E + + RT
Sbjct: 247 FDFSLDIDEMTMIDLLNKNERT 268
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 65.7 bits (153), Expect = 6e-10
Identities = 44/153 (28%), Positives = 69/153 (45%), Gaps = 3/153 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF Q Q+ I+ G KP QIE + Q ++ I+ A+ P G
Sbjct: 141 NIGVSNFNQTQMADILAHGTVKPVVDQIETHPYFQQNDMHAYLESQGILHEAWSPLGG-- 198
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+A + D + +A ++ + Q LR+ ++ VV+PKS+H+ R +QN +
Sbjct: 199 ---GNNNA----LTDSVINELAAAHDVSAAQIILRWHVQREEVVIPKSIHEARIQQNRDI 251
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP---QTKWSK 57
F +E DTG R P T W K
Sbjct: 252 FAFGLDEDEMKAISDLDTGKRVGPDPDDTAWLK 284
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 65.7 bits (153), Expect = 6e-10
Identities = 38/129 (29%), Positives = 65/129 (50%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++++++ + +P A Q+E N Q L + R + Y P G
Sbjct: 163 AIGVSNFSAKKLEQLLSFAVVRPAANQVEMNPMWQQRTLREVCRREGVQLCGYSPLG--- 219
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+K P +D L IAQ KT+ Q LR++ E G V+L K+ ++ R ++N+ +
Sbjct: 220 -AKGTPWGSAAVMDSGVLHDIAQTKGKTLAQICLRWMYEQGDVLLVKTYNENRMKENLDI 278
Query: 146 XXFSXTPEE 120
+ T EE
Sbjct: 279 FDWELTEEE 287
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 65.7 bits (153), Expect = 6e-10
Identities = 46/160 (28%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
+IG+SNF Q++R+++ GL KP QIE + Q L + D+ AY P G
Sbjct: 166 NIGVSNFNHEQLERLLNKPGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLGG 225
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
S D ID+ + IA+++ K+ Q +RF I+ +V+P S+ ++NI
Sbjct: 226 ---SCEGVDL----IDNPVIKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENI 278
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPDXPFQL 33
Q+ F T + + S + R H D PF +
Sbjct: 279 QVFDFELTQHDMDNILSLNRNLRLAMFPITKNHNDYPFHI 318
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 65.3 bits (152), Expect = 8e-10
Identities = 38/148 (25%), Positives = 67/148 (45%), Gaps = 1/148 (0%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL-X 327
IG+SNF ++Q+++ +KP Q+E + QP L + +I+ AY P GS+
Sbjct: 173 IGVSNFTVKKLQQLVSHCKQKPEVNQVEHHPLLQQPTLIEYCASEEILITAYSPLGSMDR 232
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P + P +D + +IA+ + Q L + ++ G +PKSV R +N+Q
Sbjct: 233 PQSLKVKDAPAVLDHPVIRAIAETRGCSPAQVVLAWDVQRGISAIPKSVKPSRLLENLQA 292
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKW 63
+ E ++ D R + W
Sbjct: 293 ADIQLSNTELQKIEALDQNFRLVNGAFW 320
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 64.9 bits (151), Expect = 1e-09
Identities = 40/129 (31%), Positives = 63/129 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SN+ Q ++ + + + P QIE + Q EL + RE DI +Y P L
Sbjct: 149 AIGVSNYHQSHLEATLKTAVIAPVINQIEHHPYLQQEELLRFQREKDIKIASYGP---LT 205
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P P P D ++ +A KY T + LR+ I+ G V + S + R ++ +Q+
Sbjct: 206 PILRAPGGPV----DPKVSELAAKYKVTEGEVLLRWSIDRGDVAVTTSSKESRLQEFLQV 261
Query: 146 XXFSXTPEE 120
F TPEE
Sbjct: 262 LTFQLTPEE 270
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 64.5 bits (150), Expect = 1e-09
Identities = 42/140 (30%), Positives = 70/140 (50%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG++NF ++ ++ P QIE + Q EL + ++ I+ A+ P G
Sbjct: 136 IGVANFQIQHLEELMKHSRITPMINQIETHPEFPQNELHQYLTKHKILHEAWAPLGQ--G 193
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
+KA +++ L IA + KTV Q LR+ I+ G +++PKS + +R ++NIQL
Sbjct: 194 NKAL-------LENTVLKKIASNHEKTVAQVILRWHIQRGIIIIPKSSNPKRIKENIQLF 246
Query: 143 XFSXTPEEXNLXKSFDTGXR 84
F + EE +TG R
Sbjct: 247 DFELSSEEMEKINQLNTGKR 266
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 64.5 bits (150), Expect = 1e-09
Identities = 41/121 (33%), Positives = 60/121 (49%), Gaps = 2/121 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXREN--DIVXMAYXPFGS 333
SIG+SNF +I+ ++ + P QIE + QP L K +E +I+ +AY P G+
Sbjct: 176 SIGVSNFTIEKIEELLKTARIPPAVNQIEAHPYLQQPALHKYLKEKVTNILSVAYSPLGN 235
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
+ P +DD + IAQK NK + + ++ G VLPKSV R E N
Sbjct: 236 NIYNA------PRVVDDPTVKEIAQKLNKDPAALLISWAVQRGTSVLPKSVTPSRIESNF 289
Query: 152 Q 150
Q
Sbjct: 290 Q 290
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 64.1 bits (149), Expect = 2e-09
Identities = 39/129 (30%), Positives = 62/129 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF I ++ + P QIE + E+ K + ++I+ A+ P G
Sbjct: 147 AIGVSNFMPHHIAELMKTAKVAPAVDQIEVHPGWPHTEVVKYLQAHNILVEAWAPLGGQG 206
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + ++ IA KY KT Q LR++++ G + LPKSVHKER N +
Sbjct: 207 AKV---------LTNPTMIQIADKYQKTPAQVCLRWVLQQGILPLPKSVHKERMISNQNI 257
Query: 146 XXFSXTPEE 120
F T E+
Sbjct: 258 FDFELTDED 266
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/144 (30%), Positives = 62/144 (43%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+ NF + IID P QIE + Q EL + IV AY P G
Sbjct: 143 SIGVCNFNAEHLSNIIDLSFFTPAINQIELHPLLNQAELREVNAGYGIVTEAYGPLGV-- 200
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+D + +AQ + KT Q LR+ I+LG VV+ +S + +R N+++
Sbjct: 201 ---------GRLLDHAAVTGVAQAHGKTPAQVLLRWSIQLGNVVIARSANPDRITSNLEV 251
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP 75
F T +E D G R P
Sbjct: 252 FDFELTDDEMATLNGLDEGTRFRP 275
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 64.1 bits (149), Expect = 2e-09
Identities = 41/129 (31%), Positives = 64/129 (49%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + IQ ID + P Q++ + PE+ + +N+I+ A+ P
Sbjct: 165 SIGVSNFGKKHIQEFIDQKVPLPTVNQVDLHPFMRHPEIVEICEQNEILLEAWGPL---- 220
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A R D +V IA++ K Q LR+ I+ G VV+PKSV ++R N ++
Sbjct: 221 -------ARAMRFDHPVVVKIAKEKGKDAAQIMLRWGIQHGFVVIPKSVSQKRIVSNSKI 273
Query: 146 XXFSXTPEE 120
F + EE
Sbjct: 274 FDFELSSEE 282
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 63.7 bits (148), Expect = 2e-09
Identities = 39/138 (28%), Positives = 66/138 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
++G+SNF + + ++ KP QIE + Q + + +N+I + P G
Sbjct: 141 ALGVSNFMEHHLTPLLQHATIKPTVNQIEYHPGYMQQDCVQFCNDNNIQVEGWSPLG--- 197
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D D+E L +A KYNKTV Q ++R+ I+ + LPKSV R +N ++
Sbjct: 198 ----RGDV----FDNEVLKQLAHKYNKTVAQLSIRWAIQNNVIPLPKSVTPNRIIENFEV 249
Query: 146 XXFSXTPEEXNLXKSFDT 93
F+ + + L DT
Sbjct: 250 SDFNISESDMALINKIDT 267
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 63.3 bits (147), Expect = 3e-09
Identities = 40/151 (26%), Positives = 71/151 (47%), Gaps = 3/151 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG++NF + ++ KP QIE Q +L + I +A P G
Sbjct: 165 SIGVANFNCQMVLDLLSYAKIKPVVNQIEVTPYLPQIDLINFLKRCKIETVAISPLGRAG 224
Query: 326 PSKAQPDAPPPRIDDERLVS-IAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
+ P+ ++ +E + IAQK+ K+V Q LR L++ +++PK+ +R ++N +
Sbjct: 225 CFENTPEGMKIKLLEEDIFKQIAQKHKKSVVQVILRCLVQREIMMIPKTAKLDRLKENSE 284
Query: 149 LXXFSXTPEEXNLXKSFDTGXR--TLPQTKW 63
+ F T E+ S + G R L ++W
Sbjct: 285 IFDFELTEEDMKQIYSLENGTRAINLKHSQW 315
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 63.3 bits (147), Expect = 3e-09
Identities = 42/139 (30%), Positives = 62/139 (44%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF +QR+ P QIE + E+ + E+ I A+ P
Sbjct: 145 SIGVSNFQVNHLQRLAQEATVVPAVNQIEVHPYFGNEEVRRHCGEHQIGVEAWSPI---- 200
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A +DD + ++A + K+ Q LR+ +E G +V PKSV R E+N L
Sbjct: 201 -------AQGKVLDDPTVTAVANRLGKSPAQVVLRWHVERGDIVFPKSVTPSRMEENFAL 253
Query: 146 XXFSXTPEEXNLXKSFDTG 90
F T E+ L + D G
Sbjct: 254 FDFELTEEDLALISALDKG 272
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 63.3 bits (147), Expect = 3e-09
Identities = 40/141 (28%), Positives = 66/141 (46%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SNF +Q +I+ KP Q E + + + ++N I+ AY P
Sbjct: 157 IGVSNFNINHLQHLIEKSEFKPEMNQFEIHPLCFNKKTIEFCQKNGILVEAYSPLAR--- 213
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
+ + P I+ +AQKY KTV Q LR+ ++ V++PKS +R ++NI +
Sbjct: 214 -QHEKVMKHPLINQ-----LAQKYKKTVAQVILRWALQNNMVIIPKSKTPQRIQENIDIL 267
Query: 143 XFSXTPEEXNLXKSFDTGXRT 81
F+ +P+E D T
Sbjct: 268 DFALSPQELEQMNQLDENLHT 288
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 62.9 bits (146), Expect = 4e-09
Identities = 43/129 (33%), Positives = 63/129 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++R+ P QIE + Q + E I A+ P GS
Sbjct: 137 AIGVSNFLPEHLERLTAETSVIPAVNQIELHPHLQQHAAREVHAEQGIATEAWSPLGS-- 194
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
K D P +V+IAQK+ +T Q LR+ ++LG VV+PKSV R ++NI +
Sbjct: 195 -GKGILDIPA-------IVAIAQKHGRTPAQVVLRWHLQLGNVVIPKSVTPSRIKENIDV 246
Query: 146 XXFSXTPEE 120
FS E+
Sbjct: 247 FGFSLDTED 255
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 62.9 bits (146), Expect = 4e-09
Identities = 43/139 (30%), Positives = 66/139 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ ++ P QIE + + E + R +I A+ PF
Sbjct: 136 AIGVSNFYPDRLMDLMVHHEIVPAVNQIEIHPFYQRQEEIEFMRNYNIQPEAWGPFAEGR 195
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ Q L SIA+KY KTV Q LR+L + G V +PK+V +ER ++NI +
Sbjct: 196 KNIFQNGV---------LRSIAEKYGKTVAQVILRWLTQKGIVAIPKTVRRERMKENISI 246
Query: 146 XXFSXTPEEXNLXKSFDTG 90
F T E+ + D G
Sbjct: 247 FDFELTQEDMEKIATLDEG 265
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 62.9 bits (146), Expect = 4e-09
Identities = 43/140 (30%), Positives = 74/140 (52%), Gaps = 3/140 (2%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLE---KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFG 336
+IG+SNF + R++D L KP QIE + + E + + ++ FG
Sbjct: 131 AIGVSNF---EADRLVDFCLHVDVKPVINQIELHPLRQRIEDLHWNNKYGVAVESWASFG 187
Query: 335 SLXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
A +++ LVS+A+KYNKTVPQ LR+LI+ VV+PK+V + R ++N
Sbjct: 188 R---------ATSEIMENPILVSLAEKYNKTVPQIILRWLIQQNIVVIPKTVTESRLKEN 238
Query: 155 IQLXXFSXTPEEXNLXKSFD 96
+ + F + ++ +L K+ +
Sbjct: 239 MDIFDFEISDDDMDLIKTIN 258
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 62.9 bits (146), Expect = 4e-09
Identities = 38/120 (31%), Positives = 64/120 (53%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF Q I+ I+++G P QIE ++ EL ++ I AY P L
Sbjct: 146 SIGVSNFLQEDIENIVNNGTITPAVNQIEVHIGKVPVELMDYCKKLGIKIEAYSP---LS 202
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
K ++D+++++ A+KYN T Q L F ++LG +V+PKS + ++N+ +
Sbjct: 203 HGKL--------LNDDQIIAYAKKYNVTPAQLMLAFDMQLGCIVIPKSDNVTEMKENLNI 254
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 62.9 bits (146), Expect = 4e-09
Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 3/148 (2%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS-- 333
+IG+SNF ++ +++++ P Q+E + Q +L + I+ AY P G+
Sbjct: 159 AIGVSNFSVKRLNKLLETASIVPACNQVELHPYLPQEKLKEFCDSKGILLTAYSPLGNPG 218
Query: 332 -LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
L P K + + P +++ + IA K+N +V + LR+ I+ G VLPKS ++ N
Sbjct: 219 RLVP-KERLEREPKVMEEPVIKEIAAKHNCSVARVLLRWGIQRGYPVLPKSTSRDHLHDN 277
Query: 155 IQLXXFSXTPEEXNLXKSFDTGXRTLPQ 72
T +E KS T R L Q
Sbjct: 278 FSALGLVLTDDEMAAIKSITTRQRYLTQ 305
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 62.9 bits (146), Expect = 4e-09
Identities = 40/143 (27%), Positives = 63/143 (44%), Gaps = 2/143 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFG--S 333
+IG++NF I ++ KP LQIE + Q L K +E I AY FG S
Sbjct: 164 NIGVANFNCQAILDLLSYAKIKPAVLQIEIHPLLPQERLVKWVQEQGIQVTAYSSFGPTS 223
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
+ + + SIA K+N Q LR+ ++ V+PKSVH++R + N+
Sbjct: 224 YVDLCESGKTYSSLLANADVKSIANKHNANTGQILLRYALDRNIAVIPKSVHEDRMKSNL 283
Query: 152 QLXXFSXTPEEXNLXKSFDTGXR 84
+ ++ + S T R
Sbjct: 284 DILNIQLDQDDRKILNSLKTNQR 306
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 62.5 bits (145), Expect = 5e-09
Identities = 37/141 (26%), Positives = 65/141 (46%), Gaps = 1/141 (0%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+ N+ + ++ KP LQIE + Q L + R ++ A+ P GSL
Sbjct: 170 IGVCNYSAVLLHDLMSYARIKPAMLQIESHPYLTQEALLRTARSYNMAVTAFSPLGSLSY 229
Query: 323 SKA-QPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ A + D +++ AQ+ T Q LR+ I+ G V+PK+ + +R +N+ L
Sbjct: 230 VELNMAGANDTVLTDPSVLAAAQRNGVTAAQVVLRWGIQRGTAVIPKTSNPQRLIENLTL 289
Query: 146 XXFSXTPEEXNLXKSFDTGXR 84
F+ EE + + + R
Sbjct: 290 TEFTLNDEEMDAISALNQNHR 310
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 62.5 bits (145), Expect = 5e-09
Identities = 43/139 (30%), Positives = 63/139 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF +QR+ D P Q+E + Q EL ++ IV A+ P G
Sbjct: 191 SIGVSNFTPVYLQRLFDETGIVPVVNQVELHPRLQQHELRAFHAKHRIVTEAWSPLGQ-- 248
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D L IAQK+ ++ Q +R+ I+ G VV+PKSV R +N +
Sbjct: 249 ---------GTLLADPVLAGIAQKHGRSAAQVIIRWHIQQGLVVIPKSVTPSRIAENANV 299
Query: 146 XXFSXTPEEXNLXKSFDTG 90
F+ E+ S D G
Sbjct: 300 FDFTLDAEDMAAIASLDAG 318
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 62.1 bits (144), Expect = 7e-09
Identities = 49/156 (31%), Positives = 71/156 (45%), Gaps = 1/156 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ I+ S P Q+E + Q E + + I+ A+ P G
Sbjct: 142 AIGVSNFLPHHLEPILASANVAPMVDQLEFHPGYTQDEAVAFCQNHSILVEAWSPLGR-- 199
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
++ + R+ E VS A Q LRF ++ G + LPKS ER +N+ L
Sbjct: 200 -NRLTGNGVLTRLAAEHGVSPA--------QICLRFALQRGVLPLPKSSSPERMAENLDL 250
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWS-KHPDXP 42
FS T EE T+PQT WS +HPD P
Sbjct: 251 FSFSLTGEEM-------AALSTMPQTGWSGEHPDRP 279
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 62.1 bits (144), Expect = 7e-09
Identities = 43/151 (28%), Positives = 68/151 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ ++ + P Q+E N Q +L + + N I+ +AY G++
Sbjct: 161 AIGVSNFSCKKLSDVLANAKVPPAVNQVEVNPCWQQKQLTEFCKSNGILVVAYAALGAVG 220
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ E L IA+ TV Q LR+ E G VL KS +KER EQN+Q+
Sbjct: 221 TFYGTNRV----MGSEVLNEIARIRGNTVAQVCLRWAYEQGIGVLVKSFNKERMEQNLQI 276
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWSKH 54
++ + +E G L S H
Sbjct: 277 FNWTLSDDESKKISEIPQGRACLGTDYTSVH 307
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 62.1 bits (144), Expect = 7e-09
Identities = 42/144 (29%), Positives = 62/144 (43%), Gaps = 3/144 (2%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + ++ +P LQIE + Q L ++ I AY FG L
Sbjct: 162 SIGVSNFSAQLLMDLLRYARIRPATLQIEHHPYLTQERLVTYAQKEGIAVTAYSSFGPLS 221
Query: 326 PSKAQ-PDA--PPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
+ DA P D + + IAQK+ KT Q LR+ + V+PKS R QN
Sbjct: 222 FVELDLKDAHETPKLFDHDVIKGIAQKHGKTPAQVLLRWATQRNIAVIPKSNDPTRLAQN 281
Query: 155 IQLXXFSXTPEEXNLXKSFDTGXR 84
+ + + E + S + R
Sbjct: 282 LDVTGWDLETSEIEVISSLNRNLR 305
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 62.1 bits (144), Expect = 7e-09
Identities = 37/129 (28%), Positives = 63/129 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++++++ +P Q+E N Q L + R + Y P G
Sbjct: 161 AIGVSNFSAKKLEQLLSLAAVRPAVNQVEVNPMWQQRTLREVCRREGVQLCGYSPLG--- 217
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+K P +D L IA KT+ Q LR+L E G V+L K+ +++R ++N+ +
Sbjct: 218 -AKGTPWGSAAVMDSGVLQEIAGAKGKTLAQICLRWLYEQGDVLLVKTYNEKRMKENLDI 276
Query: 146 XXFSXTPEE 120
+ T EE
Sbjct: 277 FNWELTDEE 285
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 61.7 bits (143), Expect = 9e-09
Identities = 41/144 (28%), Positives = 65/144 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF IQR+I+ P QIE + Q +L ++IV ++ P
Sbjct: 134 SIGVSNFQPEHIQRLINETGVHPVINQIELHPLLQQRQLHAWNATHNIVTESWSPLAQGG 193
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D++ + + QKY KT Q +R+ I+ G +V+PKS R ++N +
Sbjct: 194 ENV---------FDNQLVQHLTQKYGKTPAQVVIRWHIDNGMIVIPKSTTLSRIKENFDV 244
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP 75
F E+ + D G R P
Sbjct: 245 FDFKLEKEDLTAMTTLDIGKRLGP 268
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 61.7 bits (143), Expect = 9e-09
Identities = 40/137 (29%), Positives = 63/137 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF Q+ + KP QIE N + K +++D+ A+ PF
Sbjct: 134 SIGVSNFWPDQLMNLQLMSNVKPVVNQIEVNPWFQREPEVKWNQKDDVAVEAWAPFA--- 190
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + L I +KY K+ Q LR+LI+ G +V+PKSVH R ++NI +
Sbjct: 191 ------EGKDGIFTNPVLTEIGKKYGKSNGQVILRWLIQRGIIVIPKSVHDARQKENIDI 244
Query: 146 XXFSXTPEEXNLXKSFD 96
F ++ + D
Sbjct: 245 FDFELNNDDMQKIAALD 261
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 61.7 bits (143), Expect = 9e-09
Identities = 42/144 (29%), Positives = 62/144 (43%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+ NF +QR+ID P QIE + Q +L + I ++ P
Sbjct: 134 SIGVCNFHIPHLQRLIDETGIAPTVNQIELHPLLQQRQLHAWNATHHIATESWSPLAQGG 193
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
D E + +AQ+YNKT Q +R+ ++ G +V+PKSV R +N ++
Sbjct: 194 KGV---------FDQEIIRKLAQQYNKTPAQIVIRWHLDSGLIVIPKSVTPARIRENFEV 244
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP 75
F EE D G R P
Sbjct: 245 FDFKLQKEELLAITKLDCGKRLGP 268
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 61.3 bits (142), Expect = 1e-08
Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 3/150 (2%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+ NF + Q+ +I + P QIE + Q L R IV A+ P G
Sbjct: 137 AIGVCNFLEDQLDELIAASDVVPAVNQIELHPYFAQKPLLAKNRALGIVTEAWSPIGGAI 196
Query: 326 PSKAQPDAPPPR---IDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
+ D R + D + +IA+ + ++ Q LR+ + V +PKSV+ ER +N
Sbjct: 197 -NDGDGDNHGGRKHPLTDPVITTIAEAHGRSAAQVILRWHFQNDVVAIPKSVNPERIAKN 255
Query: 155 IQLXXFSXTPEEXNLXKSFDTGXRTLPQTK 66
I + F+ + E DTG R P +
Sbjct: 256 IDVFDFALSDAEMAQLDELDTGVRIGPDPR 285
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/123 (32%), Positives = 62/123 (50%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF I+ + S P Q+E + QPE+ + ++N+IV A+ PF
Sbjct: 150 AIGLSNFLVHHIEALKKSAKILPMVNQLEFHPGYLQPEIVEYCQKNNIVVQAWSPFSQ-- 207
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
SK ++++ LV +A+KY TV Q L ++I+ V LPKS ER N +
Sbjct: 208 -SKV--------LENKTLVQLAKKYEVTVAQLILNWIIQKDIVPLPKSKTPERIRSNFDV 258
Query: 146 XXF 138
F
Sbjct: 259 FNF 261
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 60.9 bits (141), Expect = 2e-08
Identities = 38/137 (27%), Positives = 71/137 (51%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF ++RI+D+ P QIE + Q L + +++I ++ P G
Sbjct: 139 SIGVSNFESEHLERIMDATGVVPVVNQIELHPDFQQRALREFHEKHNIRTESWRPLG--- 195
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
K + + DER+ IA+K+++T Q +R+ ++ G +V+PKSV+ +R +N+ +
Sbjct: 196 --KGRV------LSDERIGKIAEKHSRTPAQVVIRWHLQNGLIVIPKSVNPKRLAENLDV 247
Query: 146 XXFSXTPEEXNLXKSFD 96
F ++ + D
Sbjct: 248 FGFVLDADDMQAIEQMD 264
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 60.5 bits (140), Expect = 2e-08
Identities = 45/153 (29%), Positives = 70/153 (45%), Gaps = 5/153 (3%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFG--S 333
SIG+SNF IQ ++ KP ALQIE + Q L + + +DI +AY FG S
Sbjct: 166 SIGVSNFQGSLIQDLLRGCRIKPVALQIEHHPYLTQEHLVEFCKLHDIQVVAYSSFGPQS 225
Query: 332 LXPSKAQ-PDAPPPRIDDERLVSIAQKY-NKTVPQXALRFLIELGAVVLPKSVHKERXEQ 159
Q P +++ + ++Q + T Q LR+ + G V+PKS KER
Sbjct: 226 FIEMDLQLAKTTPTLFENDVIKKVSQNHPGSTTSQVLLRWATQRGIAVIPKSSKKERLLG 285
Query: 158 NIQL-XXFSXTPEEXNLXKSFDTGXRTLPQTKW 63
N+++ F+ T +E + + R W
Sbjct: 286 NLEIEKKFTLTEQELKDISALNANIRFNDPWTW 318
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 60.1 bits (139), Expect = 3e-08
Identities = 41/143 (28%), Positives = 65/143 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IGISNF + + KP QIE N+ QP L + ++ ++ AY P
Sbjct: 148 NIGISNFNVQMLLDLYSYCKIKPVVNQIEVNVYCQQPRLLEFCKKLNLHVTAYCPLARCQ 207
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ +D L ++ KY K+V Q L+FL+ LG V+PK+ + ER +NI+
Sbjct: 208 NTD----------NDALLTELSTKYKKSVCQIMLQFLLSLGVSVIPKTQNLERLRENIES 257
Query: 146 XXFSXTPEEXNLXKSFDTGXRTL 78
FS + K + R +
Sbjct: 258 TDFSLDEADIAKLKGLNKNFRLI 280
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 60.1 bits (139), Expect = 3e-08
Identities = 38/117 (32%), Positives = 59/117 (50%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF ++ ++ P Q+E + Q EL + ++N+IV A+ PFGS+
Sbjct: 186 SIGVSNFSIPYLEELLKEAEVVPAVNQVELHPLLPQLELMEFCKKNNIVMTAFSPFGSVG 245
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
P + +E +VS+A KYN + + I G VV+PKSV R +N
Sbjct: 246 ---------GPLLKNELVVSLADKYNTSPGGILTSYHIGNGTVVIPKSVTNSRIVEN 293
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 60.1 bits (139), Expect = 3e-08
Identities = 38/129 (29%), Positives = 60/129 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + ++D KP Q+E NL EL + + AY PFGS
Sbjct: 165 NIGVSNFNIRRTSEVVDEASIKPVVNQVEVNLGVHNEELRNYAHAHGVTLQAYSPFGS-N 223
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ A+ ++D +V +AQ+ N T Q L + + + + KSV ER E+N ++
Sbjct: 224 QNVAK------SLEDPVVVDVAQRNNITPAQVLLAWTLGRDIIPISKSVTPERIEENFRV 277
Query: 146 XXFSXTPEE 120
EE
Sbjct: 278 LDIQLAEEE 286
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 60.1 bits (139), Expect = 3e-08
Identities = 41/141 (29%), Positives = 66/141 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ ++ + KP QIE + EL + I AY P
Sbjct: 152 TIGVSNFDVEELDHLLANCRIKPAVNQIESHPFFAHEELREACISRGIHIQAYSPM---- 207
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
AQ A +D + +IA K+ KT Q L++ + G ++LPKS+ K R E N QL
Sbjct: 208 ---AQGQA----LDRPEIKTIASKHGKTPAQILLKWGLTHGNIILPKSLTKHRIESNAQL 260
Query: 146 XXFSXTPEEXNLXKSFDTGXR 84
F ++ ++ + D G +
Sbjct: 261 FDFELDSDDMDVLDNLDEGMK 281
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 59.7 bits (138), Expect = 4e-08
Identities = 36/120 (30%), Positives = 61/120 (50%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ I++ P QI+ L +P++ K E+ ++ AY P
Sbjct: 145 AIGVSNFAVRDLKNILNQATIPPMVNQIQYYLGFTEPKITKFSEEHAMLVEAYSPL---- 200
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A +D+ ++ + A KY +V Q ALRF+++ G + LPK+V+ E N QL
Sbjct: 201 -------ATGGVLDNPQVQAYADKYGVSVAQLALRFVLQNGVLPLPKAVNPAHIEANTQL 253
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 59.7 bits (138), Expect = 4e-08
Identities = 41/139 (29%), Positives = 65/139 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF Q QRI+D P Q+E + Q EL ++++I A+ P G
Sbjct: 127 AIGLSNFDVAQTQRILDECEVVPTINQVECHPYFPQTELKALLKDHNITLQAWYPLGGRG 186
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ P + +A++++K+ Q LR+ I+ G +V+P S QNI L
Sbjct: 187 NDSIMSE---PIVQ-----GLAEEHSKSPAQVLLRWHIQQGHIVIPGSKTPSHIAQNIDL 238
Query: 146 XXFSXTPEEXNLXKSFDTG 90
F+ T E+ S D G
Sbjct: 239 FDFALTDEDMAQIDSLDKG 257
>UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1;
Coccidioides immitis|Rep: Putative uncharacterized
protein - Coccidioides immitis
Length = 324
Score = 59.7 bits (138), Expect = 4e-08
Identities = 35/116 (30%), Positives = 58/116 (50%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SNF +++R++ P Q+E N Q +L + E++I AY P G
Sbjct: 161 IGVSNFSTPKLKRLLSVCRIFPVVNQVELNPYFPQKQLLRFCHEHEIHVTAYGPLGCTPV 220
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
P ++D + ++A++Y++T Q L LI LG V+PKS + R +N
Sbjct: 221 PYLIGRKTPGPLEDCTVKAMAERYSRTPAQIILAHLIMLGVSVIPKSNNLSRISEN 276
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 59.3 bits (137), Expect = 5e-08
Identities = 40/143 (27%), Positives = 63/143 (44%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SN+ + +++ P A Q+E + Q +L E I+ M Y P
Sbjct: 139 SIGVSNYSIEDLDELLEFASILPHANQVELHPWFHQADLKNYCDELGILTMGYCPL---- 194
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A ++DE L IA KY K+ Q LR+ I+ +PKS R ++N +
Sbjct: 195 -------AKGKYLEDETLCKIASKYQKSPAQICLRWSIQQNVPTVPKSTDCRRLKENTNV 247
Query: 146 XXFSXTPEEXNLXKSFDTGXRTL 78
F + E+ N SF + R +
Sbjct: 248 FDFELSAEDMNTLNSFSSQNRKI 270
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 58.8 bits (136), Expect = 7e-08
Identities = 41/139 (29%), Positives = 66/139 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ + P QIE N Q + + R+ + A+ PF
Sbjct: 131 AIGVSNFGVDRVVDLAAFNDITPQVNQIEINPFQQQSKNIEALRKEGVAVEAWAPF---- 186
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
++ + D + L IA+KY K+V Q LR+LIE +VL KSV ER QN+ +
Sbjct: 187 -AEGKNDI----FTNPILTKIAEKYGKSVAQVILRWLIEQDIIVLAKSVKPERMAQNLAV 241
Query: 146 XXFSXTPEEXNLXKSFDTG 90
F + E+ + + + G
Sbjct: 242 FDFELSEEDKSAIATLNQG 260
>UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas
mobilis|Rep: Putative oxidoreductase - Zymomonas mobilis
Length = 273
Score = 58.8 bits (136), Expect = 7e-08
Identities = 43/138 (31%), Positives = 64/138 (46%), Gaps = 1/138 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRII-DSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
SIG+SNF + II DSG+ P QIE + Q EL E IV ++ P G
Sbjct: 133 SIGVSNFTIDHLDHIIADSGV-VPAVNQIELHPYFQQKELRAYHAERGIVTTSWSPLGR- 190
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
++D + IA K+ KT Q L + + LG V+PK+ K R ++N++
Sbjct: 191 ----------GAALNDPVIREIALKHGKTPAQVVLNWHLSLGLTVIPKASSKARLQENLE 240
Query: 149 LXXFSXTPEEXNLXKSFD 96
F+ E+ +S D
Sbjct: 241 ADSFALDEEDMQRIESLD 258
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 58.8 bits (136), Expect = 7e-08
Identities = 35/129 (27%), Positives = 63/129 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + + ++++ KP QI N Q E+ ++ D++ AY P G+
Sbjct: 146 AIGVSNFRKHHLDALMETAEIKPVVNQIFLNPSDLQSEVVTENKKLDLLSEAYSPLGT-- 203
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ +E + +A Y K+ Q +R+ ++ G + LPKSVH E + N +
Sbjct: 204 ---------GGLLGNEVVKEVAANYGKSTAQVLIRWSLQHGFLPLPKSVHPEYIKANADV 254
Query: 146 XXFSXTPEE 120
F +PE+
Sbjct: 255 FDFEISPED 263
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 58.8 bits (136), Expect = 7e-08
Identities = 44/153 (28%), Positives = 70/153 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SN ++RI+ + P QIE + Q E+ +D+ ++ P G
Sbjct: 135 SIGVSNHLVPHLERIVAATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWGPLG--- 191
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + D E + + A + KT Q LR+ ++ G VV PKSV +ER E+N+ +
Sbjct: 192 --QGKYDL----FGAEPVTAAAAAHGKTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDV 245
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHPD 48
F T E + D G + + S HPD
Sbjct: 246 FDFDLTDTEIAAIDAMDPGDGS---GRVSAHPD 275
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 58.8 bits (136), Expect = 7e-08
Identities = 37/142 (26%), Positives = 66/142 (46%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+ N+ ++ R++ S P Q+E + ++F+ +++ I AY P GS
Sbjct: 163 IGVCNYTVTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHVTAYSPLGSSEK 222
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
+ A D + +A K NKT Q +++ ++ G V+PKS ER ++NIQ+
Sbjct: 223 NLAH---------DPVVEKVANKLNKTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVF 273
Query: 143 XFSXTPEEXNLXKSFDTGXRTL 78
+ E+ + S R L
Sbjct: 274 GWEIPEEDFKVLCSIKDEKRVL 295
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 58.4 bits (135), Expect = 9e-08
Identities = 37/120 (30%), Positives = 60/120 (50%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF Q ++ I+ + KP A QI ++ L ++ +I+ AY P
Sbjct: 152 SIGVSNFLQKDLENILKNCKTKPAANQILCHIGNTPFTLLDYCKKQNILAEAYSPI---- 207
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A + D R++ +A+KYN + Q +R+ +ELG V LPKS + +N Q+
Sbjct: 208 -------AHGELLKDPRVIELAKKYNVSPAQICIRYTLELGLVSLPKSKTPKYIAENAQV 260
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 58.4 bits (135), Expect = 9e-08
Identities = 39/143 (27%), Positives = 68/143 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+S+F ++ +I KP QIE N+ + + + + + A+ PF
Sbjct: 132 AIGVSSFWNERLADLITFNDVKPAVNQIETNVWNQEWKSQQYMEKEGVQPEAWAPFAE-- 189
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A P +++ IA+K++KT Q LR+ ++ VV+PKSVHK+R +N +
Sbjct: 190 --GANHIFTNPLLEE-----IAEKHHKTTAQVMLRWFLQRNYVVIPKSVHKKRLAENYDV 242
Query: 146 XXFSXTPEEXNLXKSFDTGXRTL 78
F ++ K+ D G L
Sbjct: 243 FDFELDADDMKKIKTLDQGHSIL 265
>UniRef50_A2UBY5 Cluster: Plant-metabolite dehydrogenase; n=1;
Bacillus coagulans 36D1|Rep: Plant-metabolite
dehydrogenase - Bacillus coagulans 36D1
Length = 113
Score = 58.4 bits (135), Expect = 9e-08
Identities = 28/64 (43%), Positives = 39/64 (60%)
Frame = -2
Query: 275 LVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLXXFSXTPEEXNLXKSFD 96
LV + +KY KT Q LR+ +E G VV+PKSV R ++N ++ FS TPE+ S +
Sbjct: 31 LVELGKKYGKTPAQIVLRWHVERGIVVIPKSVTPSRIKENSEIFDFSLTPEDMEKIASLN 90
Query: 95 TGXR 84
TG R
Sbjct: 91 TGKR 94
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 58.4 bits (135), Expect = 9e-08
Identities = 36/134 (26%), Positives = 65/134 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIGI N+ ++ ++++ P Q+E N Q L + ++ I A+ P G+
Sbjct: 162 SIGICNYGTKKLTKLLEIATIPPAVNQVEMNPSWQQGNLREFCKQKGIHVSAWSPLGAYK 221
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
++++ L IA KT+ Q ALR++ + G+ + KS +KER +QN+++
Sbjct: 222 IFWGSGAV----MENQILQDIATAKGKTIAQVALRWVYQQGSSAMAKSFNKERMKQNLEI 277
Query: 146 XXFSXTPEEXNLXK 105
F + EE K
Sbjct: 278 FDFELSEEELEKIK 291
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 58.4 bits (135), Expect = 9e-08
Identities = 37/126 (29%), Positives = 63/126 (50%), Gaps = 2/126 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLEK-PXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
+IG+SNF + ++ ++++S G+ P QIE + QP+LF + DI AY P G
Sbjct: 150 AIGVSNFNKKKLDKLLNSEGVNVVPVINQIEAHPLLTQPDLFDYLKSKDIYITAYSPLGH 209
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
S + ++ + IA+K+N Q + + ++ G +V+PKS ER NI
Sbjct: 210 ADAST---------LKNKVVTDIAKKHNANAGQVLISWGVQRGTIVIPKSTTDERIIDNI 260
Query: 152 QLXXFS 135
+ S
Sbjct: 261 KTFTLS 266
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 58.0 bits (134), Expect = 1e-07
Identities = 39/137 (28%), Positives = 64/137 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
S+ ++NF ++ I+ P Q+E + Q E RE +V A+ P G
Sbjct: 147 SVAVANFYPEVLREIVAETGIAPVLNQVELHPGFSQAEQRAVDRELGVVTEAWSPLG--- 203
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D+ ++ E + IAQ Y KT Q LR++ +LG V+PKS + +R +N+ +
Sbjct: 204 ----RGDS----LNAEAITLIAQCYEKTPAQVTLRWIHQLGCSVVPKSANPQRQRENLDI 255
Query: 146 XXFSXTPEEXNLXKSFD 96
F E+ N S D
Sbjct: 256 FDFELNTEDMNSITSLD 272
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 58.0 bits (134), Expect = 1e-07
Identities = 34/129 (26%), Positives = 64/129 (49%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
S+G+SNF ++ + + P QIE + QP++ + + + I ++ P L
Sbjct: 139 SLGVSNFWPEHLEALFQTAKVSPSVNQIEFHPGYWQPQVTEFCKNHGIAVESWSP---LA 195
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
K ++ L+ +++KY K+V Q LR++I+ + +PKS ER ++NI +
Sbjct: 196 RGKV--------FGNDLLIGLSKKYQKSVSQVCLRWIIQHDVIAIPKSSSPERIKENIDV 247
Query: 146 XXFSXTPEE 120
F + EE
Sbjct: 248 FDFELSKEE 256
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 57.6 bits (133), Expect = 2e-07
Identities = 38/142 (26%), Positives = 65/142 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + R+++ G P QIE + Q + ++N IV A+ P
Sbjct: 133 AIGVSNFHIPHLTRVLEEGTVVPAVNQIELHPFLSQEAIRAFCQKNGIVVEAWSPL---- 188
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
K + P I D IA ++ KT Q LR+ ++ + +PKSV R ++N+ +
Sbjct: 189 -MKGRDALTDPVITD-----IAARHGKTPAQVVLRWHLQHDIIAIPKSVTPSRIQENLDI 242
Query: 146 XXFSXTPEEXNLXKSFDTGXRT 81
F +P++ + RT
Sbjct: 243 FDFVLSPDDMRQIDQLNRNERT 264
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 57.6 bits (133), Expect = 2e-07
Identities = 43/151 (28%), Positives = 65/151 (43%), Gaps = 2/151 (1%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEK--PXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
IG+SNF + Q+ + D K P QIE + L K + + AY P
Sbjct: 152 IGVSNFNEAQLAALCDDPRTKIQPACNQIESHPLWSNDSLVKYSQSKGLTVTAYSPL--- 208
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
AQ ++E LV +A+KY T Q LR+ ++ VV+PKS +R N
Sbjct: 209 ----AQGGE---LFENEILVGLAKKYGVTPAQVVLRWNVQRDVVVIPKSTSAKRIASNAD 261
Query: 149 LXXFSXTPEEXNLXKSFDTGXRTLPQTKWSK 57
L F + E+ + K D ++ WS+
Sbjct: 262 LFGFELSDEDMDAMKVLDV-MKSCATAPWSE 291
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 57.6 bits (133), Expect = 2e-07
Identities = 38/119 (31%), Positives = 57/119 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SN I+ II +G P Q+E + Q L K +E I+ AY P GS
Sbjct: 187 AIGLSNAGIPIIEHIIKTGKVTPAVNQVELHPYCPQHALLKYCKEKGILLEAYSPLGSTS 246
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
P +D L+++A+K+N + + + G VVLPKSV R E N++
Sbjct: 247 S---------PLHEDPDLLAVAKKHNVPTATVLISYQVNRGVVVLPKSVTPARIESNLK 296
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 57.2 bits (132), Expect = 2e-07
Identities = 38/141 (26%), Positives = 63/141 (44%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
++G+ NF ++R+ + P QIE + Q E+ +E+ I AY P
Sbjct: 147 TLGVCNFMPADLKRLHEETGAWPAVNQIELHPTWQQREVVAFCKEHGIAVEAYSPMARGA 206
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A D + IA + + Q LR+ IE G +++PKSVH +R ++N+ L
Sbjct: 207 DLNA---------GDGTIEKIAAAHEVSPAQVILRWHIENGTIIIPKSVHADRQKENLNL 257
Query: 146 XXFSXTPEEXNLXKSFDTGXR 84
F+ T +E + D R
Sbjct: 258 FGFALTADEHAAIDALDGPTR 278
>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
YvgN - Bacillus sp. NRRL B-14911
Length = 268
Score = 57.2 bits (132), Expect = 2e-07
Identities = 35/129 (27%), Positives = 61/129 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + + + + KP QI+ NL L ++ +I +A+ P +
Sbjct: 145 AIGVSNFEENHLDELKEFAKVKPAVNQIQINLKEPNKNLLAVLKDEEITPVAWGPMKAEA 204
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
K E L I + Y+K+ Q L++ I+ G +V+PKS ++E N++L
Sbjct: 205 HQK------------EALDEIGKIYHKSGAQILLKYQIQRGVIVIPKSHNRENQASNLEL 252
Query: 146 XXFSXTPEE 120
F T E+
Sbjct: 253 FDFELTAED 261
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/132 (30%), Positives = 60/132 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF ++ + P QIE + EL + + NDI AY P
Sbjct: 121 SIGVSNFEIRHLEELRRVSGIVPAVNQIECHPLCYPKELIEYCQANDIQVQAYAPL---- 176
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A +D++ L + KY T Q LR+ ++ G V+PKSVH ER N ++
Sbjct: 177 -------ARGAYLDNDVLCVLGTKYAHTPAQIGLRWAVQKGISVIPKSVHPERIASNARI 229
Query: 146 XXFSXTPEEXNL 111
F+ E+ +L
Sbjct: 230 FDFTIDQEDMDL 241
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 57.2 bits (132), Expect = 2e-07
Identities = 30/129 (23%), Positives = 64/129 (49%), Gaps = 1/129 (0%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
+G+SNF + +++ + E P Q+E + Q +L+ + I+ Y P GS
Sbjct: 156 VGVSNFSKEKLESLKGKVEEMPEMNQVELHPYLPQNDLYSYCSKEGILLTGYSPLGSGDR 215
Query: 323 SKA-QPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
S+ + D P +D+ + +A++ N + Q + + + G V+PKS ++ R ++N++
Sbjct: 216 SEGMKADDEPSLFEDDTIKKVAERNNISKGQTLIAWAKQRGTAVIPKSTNEGRIKENLES 275
Query: 146 XXFSXTPEE 120
+ E+
Sbjct: 276 DNIELSKED 284
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 57.2 bits (132), Expect = 2e-07
Identities = 40/148 (27%), Positives = 68/148 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SN+ ++ + P A Q+E + + L K +E +I A F SL
Sbjct: 156 SIGVSNYEIVHLEELKTYAKVPPCANQLEYHPHFARIPLQKYCKEKNIFFQA---FSSLA 212
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ P I+D +V +A+K+N +VP L + + ++PKSV R +N ++
Sbjct: 213 RHE------PKLIEDPVVVELAKKHNTSVPLVLLAWALRQNVGIVPKSVTPSRIVENFKV 266
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKW 63
+ TPE+ + D G + T W
Sbjct: 267 IDIALTPEDIQSLTALDRGQHYIRCTGW 294
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 57.2 bits (132), Expect = 2e-07
Identities = 44/152 (28%), Positives = 74/152 (48%), Gaps = 5/152 (3%)
Frame = -2
Query: 503 IGISNFXQXQIQRI-IDSGLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
IG+SNF Q++R+ D G++ +P Q+E ++ Q + + + ++Y G
Sbjct: 152 IGVSNFSIEQLERMRYDPGVKIQPYCNQVESHMYLQQQPMLDYLTQRKMYMISYTCLGR- 210
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELG--AVVLPKSVHKERXEQN 156
+ + P + D L +A++ KT Q LRFL++L AVV+PKS++ + N
Sbjct: 211 --ATLKGPYGYPLLQDPVLNEVAKEIGKTPAQTNLRFLLKLSPYAVVIPKSLNPANIKGN 268
Query: 155 IQLXXFSXTPEEXNLXKSFDTGXRTL-PQTKW 63
I L F T E+ +S G R + P W
Sbjct: 269 ISL-DFDLTQEQFEKLRSRQCGWRFVNPYPNW 299
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 56.8 bits (131), Expect = 3e-07
Identities = 37/144 (25%), Positives = 64/144 (44%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG++NF Q + ++ + EKP Q+E + Q +L K E +I A+ P
Sbjct: 137 SIGVANFKQHHLSDLLVAANEKPVLNQVETHPLLPQNDLRKYLAEQNIAHAAWSPL---- 192
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A + + + IA+K+ +V Q L++ + ++ PKS+ R E+N +L
Sbjct: 193 -------AKGILMQNPVITEIAKKHQASVDQVILQWHLNRNTIIFPKSITSSRIEENSRL 245
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP 75
F + +TG R P
Sbjct: 246 SYFQLDASDMEKIDRLETGKRVGP 269
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 56.8 bits (131), Expect = 3e-07
Identities = 35/120 (29%), Positives = 59/120 (49%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
++G+SN+ + +++++ P Q+E + Q EL +E I MAY P GS
Sbjct: 158 AVGVSNYSKAWLEQLLPHATTVPAVNQVENHPQLPQQELVDFCKEKGIHIMAYSPLGS-- 215
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P + E +V IA+K++ + L + I G V+PKSV+ +R + N QL
Sbjct: 216 -------TGGPLLTAEPVVKIAEKHSISPAAVLLGYQIARGITVIPKSVNPDRIKANAQL 268
>UniRef50_Q2H1Q3 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 274
Score = 56.8 bits (131), Expect = 3e-07
Identities = 40/131 (30%), Positives = 63/131 (48%), Gaps = 2/131 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEK--PXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
++G+SNF ++R+++ K P QIE + P+L E I Y P GS
Sbjct: 124 NLGVSNFGIKNLERLLNDPSCKIVPAVNQIELHPGNPSPKLIAYCAEKGIHCSGYSPLGS 183
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
+ P +E + SIA+ N++V Q L + ++ G VLPKSV+ +R + N
Sbjct: 184 ---------SDSPLYKNETIASIAKAKNRSVQQVLLMWGVKKGWSVLPKSVNPDRVKANF 234
Query: 152 QLXXFSXTPEE 120
L + T EE
Sbjct: 235 DLDGWDLTDEE 245
>UniRef50_A6BFM9 Cluster: Putative uncharacterized protein; n=1;
Dorea longicatena DSM 13814|Rep: Putative
uncharacterized protein - Dorea longicatena DSM 13814
Length = 93
Score = 56.4 bits (130), Expect = 3e-07
Identities = 26/53 (49%), Positives = 35/53 (66%)
Frame = -2
Query: 248 KTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLXXFSXTPEEXNLXKSFDTG 90
KT Q ALRFLI+ G VV+PKSVHKER E+N + F+ + E+ ++ D G
Sbjct: 21 KTPAQVALRFLIQSGVVVIPKSVHKERMEENFNVFDFTLSEEDMKTLEALDGG 73
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/152 (23%), Positives = 64/152 (42%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
S+G++NF + ++ KP QIE + Q +L +I AY PFGS
Sbjct: 155 SMGVANFTAPMLLDLLSYAKIKPAVHQIELHPYLAQNDLVAFCYSQNIAVTAYSPFGS-- 212
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P + D + +A+ KT Q LR+ ++ V+P+S + R ++N ++
Sbjct: 213 -------TEAPVLTDPTVKEVAKGLGKTPAQVLLRWAVQRNTSVIPRSSNATRIKENFEI 265
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHP 51
F + E + + R + +W P
Sbjct: 266 ATFELSNEHMAALNTLNRNKRFVNPIEWWGFP 297
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 56.4 bits (130), Expect = 3e-07
Identities = 38/139 (27%), Positives = 67/139 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF ++R++ + P QI+ + + R + IV +Y P G+
Sbjct: 136 SIGVSNFKPAHLERLMAACDVVPAVNQIQVSPAITRIVDIAYNRRHGIVTESYSPLGA-- 193
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+AP L IAQK+ KT Q LR+ +E G V +PK+ + +R ++N+ +
Sbjct: 194 -GSDLLNAPV-------LGRIAQKHGKTPGQIVLRWHVEQGLVAIPKTANPQRMKENLDI 245
Query: 146 XXFSXTPEEXNLXKSFDTG 90
F+ ++ + + D G
Sbjct: 246 FGFTLDADDTSAIATLDGG 264
>UniRef50_Q0DHN0 Cluster: Os05g0456200 protein; n=2; Oryza sativa
(japonica cultivar-group)|Rep: Os05g0456200 protein -
Oryza sativa subsp. japonica (Rice)
Length = 229
Score = 56.4 bits (130), Expect = 3e-07
Identities = 36/113 (31%), Positives = 59/113 (52%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF +++ +++ P Q+E + Q +L K + + AY P GS
Sbjct: 95 AIGVSNFSCKKLEDLLNVARVPPAVNQVECHPVWQQGKLRKLCQSKGVHLSAYAPLGS-- 152
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKER 168
P D P + ++SIA+K K+ Q ALR+ I++G VLPKS ++ R
Sbjct: 153 PGSPGNDGPNV-LSHPTVISIAKKLQKSPAQVALRWGIQMGQSVLPKSDNEVR 204
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 56.4 bits (130), Expect = 3e-07
Identities = 35/129 (27%), Positives = 60/129 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + +++ P Q+E N Q + + I AY P G
Sbjct: 161 AIGVSNFTTKHLDKLLAVATIPPAVNQVEMNPVWQQRTVREYCAAKGIRVAAYSPLGGQN 220
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
D ++ L IA+ K++ Q +LR++ E G +PKS +KER +QN+++
Sbjct: 221 WIGEGNDV----MESPVLADIARARGKSIAQVSLRWIHEQGVTPIPKSYNKERLKQNLEI 276
Query: 146 XXFSXTPEE 120
+ T E+
Sbjct: 277 FDWELTKED 285
>UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces
cerevisiae Probable oxidoreductase YJR096W; n=2;
Yarrowia lipolytica|Rep: Similar to sp|P47137
Saccharomyces cerevisiae Probable oxidoreductase YJR096W
- Yarrowia lipolytica (Candida lipolytica)
Length = 287
Score = 56.4 bits (130), Expect = 3e-07
Identities = 38/139 (27%), Positives = 66/139 (47%), Gaps = 1/139 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
++ +SN+ ++ D+ + KP QIE + ++ E+DIV Y P L
Sbjct: 148 TLAVSNYGVKHLKEFWDADTKYKPVLNQIESSPWNVHQDIHDYCNEHDIVVEQYSP---L 204
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
K + D+ + S+A+KYNKT Q +R+ I+ G + +PKS +R + N
Sbjct: 205 IRGK--------KFDEPGVQSLAKKYNKTPAQILIRWGIDKGMLPIPKSDQPQRQKSNAD 256
Query: 149 LXXFSXTPEEXNLXKSFDT 93
+ F TP+E + D+
Sbjct: 257 VFDFKLTPDEVTALQDLDS 275
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 56.4 bits (130), Expect = 3e-07
Identities = 39/144 (27%), Positives = 62/144 (43%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ ++ P Q+E + Q +L I A+ P G
Sbjct: 145 AIGVSNFHIHHLEDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQ-- 202
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + L +I KYNKT Q LR+ I+ + +PKSVH+ER E+N +
Sbjct: 203 ---------GKLLSNPILSAIGAKYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADI 253
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP 75
F E+ + +T R P
Sbjct: 254 FDFELGAEDVMSIDALNTNSRYGP 277
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 56.4 bits (130), Expect = 3e-07
Identities = 43/151 (28%), Positives = 70/151 (46%), Gaps = 2/151 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEK--PXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
++G+SNF ++ ++ S K P A Q+E + Q EL + IV AY P GS
Sbjct: 165 AVGVSNFSINNLKDLLASQGNKLTPAANQVEIHPLLPQDELINFCKSKGIVVEAYSPLGS 224
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
DAP + + ++ IA+K N + + ++ G VVLPKSV+ +R + N
Sbjct: 225 T-------DAP--LLKEPVILEIAKKNNVQPGHVVISWHVQRGYVVLPKSVNPDRIKTNR 275
Query: 152 QLXXFSXTPEEXNLXKSFDTGXRTLPQTKWS 60
++ S E S + G + + WS
Sbjct: 276 KIFTLSTEDFEAINNISKEKGEKRVVHPNWS 306
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 56.0 bits (129), Expect = 5e-07
Identities = 39/141 (27%), Positives = 64/141 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IGISNF + +++R+++S P +Q+E + Q + + + I Y G+
Sbjct: 154 AIGISNFSKGEMERLLESCSIVPAVMQMELHPWLQQNDFVEWLKSKGIHVTQYSSLGNQN 213
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + I+D L +I KY KT Q AL + I G VL KS R +QN +
Sbjct: 214 EVYSGRERYGRLIEDPALAAIGTKYGKTGAQVALAWGITKGHSVLVKSKTPHRIQQNFE- 272
Query: 146 XXFSXTPEEXNLXKSFDTGXR 84
F E+ ++ D R
Sbjct: 273 SDFELKQEDMKAIENIDKKLR 293
>UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 293
Score = 56.0 bits (129), Expect = 5e-07
Identities = 43/138 (31%), Positives = 59/138 (42%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SNF ++ + P QIE + Q ++ K E+ I AY P
Sbjct: 146 IGVSNFGIHHLKALPPP---VPAVNQIELHPFCQQRDIVKYCEEHGIAIEAYSPLVR--- 199
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
A D+E LV +A+KY K V Q LR+ ++ G + LPKSV R E N L
Sbjct: 200 ------ANKKHYDNEVLVKVAKKYGKEVAQVLLRWSLQKGYIPLPKSVTPSRIESNADLY 253
Query: 143 XFSXTPEEXNLXKSFDTG 90
F E+ D G
Sbjct: 254 DFKLDQEDMAEIDGLDKG 271
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 56.0 bits (129), Expect = 5e-07
Identities = 38/124 (30%), Positives = 58/124 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SN+ + +++ P A Q+E + Q EL K + I+ AY P GS
Sbjct: 188 AIGVSNWSIAFLDKLLAKAKIVPAANQVELHPFLPQHELVKYCHDKGILPQAYSPLGS-- 245
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ P + DER+ SIA+ + Q + + + G V LPKSV R E N +L
Sbjct: 246 -------SGGPVLQDERVQSIAKAHKADPAQVVISWAAQRGVVALPKSVTPSRIETNGKL 298
Query: 146 XXFS 135
S
Sbjct: 299 IVLS 302
>UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 293
Score = 56.0 bits (129), Expect = 5e-07
Identities = 42/142 (29%), Positives = 63/142 (44%), Gaps = 1/142 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
S+G+SNF IQ +IDS + P QIE + Q E+ + I+ AY P
Sbjct: 150 SLGVSNFGPHHIQELIDSKPKVLPVCNQIECHPFFAQKEVRAASEAHSIIVQAYCPL--- 206
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
A D L +A + KT Q LR+L++ G V LPKS + +R +N +
Sbjct: 207 --------ARGHYYGDPTLKKVAAETGKTEAQVMLRWLVQHGIVALPKSSNLQRQVENAE 258
Query: 149 LXXFSXTPEEXNLXKSFDTGXR 84
F + E+ + D G +
Sbjct: 259 CLTFVLSDEQMKELDALDRGDK 280
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 56.0 bits (129), Expect = 5e-07
Identities = 40/136 (29%), Positives = 63/136 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++R+I KP Q+E + Q EL K +DI+ AY P G
Sbjct: 188 AIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLG--- 244
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
S P+ P + +A+KYN T + + I G +V+P+S++ R +I+
Sbjct: 245 -SHGAPNLKIPLVK-----KLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF 298
Query: 146 XXFSXTPEEXNLXKSF 99
S T +E F
Sbjct: 299 A--SLTKDELQELNDF 312
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 55.6 bits (128), Expect = 6e-07
Identities = 39/139 (28%), Positives = 56/139 (40%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SN Q+ + P Q+E N Q L + D+ A+ P G
Sbjct: 134 SIGVSNMTPTLWQKFVPQFETIPAVNQVEFNPYFQQQPLRQLLAAQDVKLEAWAPLGQ-- 191
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + +A KY+K Q LRF + G +V PKSVH R + N +
Sbjct: 192 -------GNQALFKEPIIQQLAIKYHKDAGQIILRFEHQEGVIVFPKSVHSARIKSNRDI 244
Query: 146 XXFSXTPEEXNLXKSFDTG 90
F T E ++ DTG
Sbjct: 245 FDFELTSTEMAQLRALDTG 263
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 55.6 bits (128), Expect = 6e-07
Identities = 37/137 (27%), Positives = 64/137 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IGISNF Q +I +P QIE +L Q ++ + + +IV +Y P G+
Sbjct: 128 AIGISNFNSRQTLDLIHQSSVRPMVDQIETHLFLQQWKMHEFLEKENIVHESYSPLGN-- 185
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
Q + I + L I++KY K+ Q LR+L++ V +P+S + + NI +
Sbjct: 186 ---GQQNL----ISNPVLKEISEKYGKSPIQVILRYLVQNDVVTIPRSTNPAHIKSNIDI 238
Query: 146 XXFSXTPEEXNLXKSFD 96
F ++ + D
Sbjct: 239 FDFELDNDDLKRLRVLD 255
>UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome.
precursor; n=1; Aspergillus niger|Rep: Contig An01c0460,
complete genome. precursor - Aspergillus niger
Length = 351
Score = 55.6 bits (128), Expect = 6e-07
Identities = 34/119 (28%), Positives = 59/119 (49%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SNF +++R++ S P QIE + Q EL + + N I +A+ P G
Sbjct: 198 IGVSNFNILKLERLLGSARIPPAVNQIELHPYLPQVELVRFCKANGIHLVAHQPLGGKPV 257
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ P+A P A K+ ++ Q L ++++ G V+PK+V + R +N+ L
Sbjct: 258 AAVNPNADRP----------ASKHERSPAQIILSWIVQQGISVIPKTVRQSRMVENLDL 306
>UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG07276.1 - Gibberella zeae PH-1
Length = 284
Score = 55.2 bits (127), Expect = 8e-07
Identities = 37/140 (26%), Positives = 66/140 (47%), Gaps = 1/140 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXAL-QIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
+IG+SNF + + + E P ++ QIE + Q E+ K ++N+I+ AY P
Sbjct: 145 NIGVSNFRVRHLDEMKEYATEWPPSVNQIELHPWCQQKEVVKYCQDNEIIIEAYSPL--- 201
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
A R++D + I+ K++K+ Q +R+ ++ G V LPKS +R +N
Sbjct: 202 --------ATGARLEDPLVEGISTKHDKSHAQVLIRYSLQKGWVPLPKSSRPDRISENFN 253
Query: 149 LXXFSXTPEEXNLXKSFDTG 90
+ F ++ D G
Sbjct: 254 VFDFVLDEDDMETLDDLDKG 273
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 55.2 bits (127), Expect = 8e-07
Identities = 43/137 (31%), Positives = 67/137 (48%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SN+ I+ ++D+ E P Q+E + EL N IV AY P
Sbjct: 117 IGVSNYSIELIEELVDATGEIPVVNQVEWSPFGHDLELKHYADFNGIVIQAYSPL----- 171
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
++A R+DD L A+KY KT Q +R+ +E G V +PK+ ++NI +
Sbjct: 172 TRAT------RLDDAALCETAEKYGKTPAQVLIRWNLERGTVPIPKANLHSHMKENISV- 224
Query: 143 XFSXTPEEXNLXKSFDT 93
F T E+ +L +S D+
Sbjct: 225 -FDFTLEKSDL-ESLDS 239
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 55.2 bits (127), Expect = 8e-07
Identities = 38/144 (26%), Positives = 67/144 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ ++ KP Q+E + Q EL + I A+ P
Sbjct: 137 AIGVSNFQVHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKAQGIQLEAWSPL---- 192
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ Q +D+E L IA+K+NK+V Q LR+ ++ V +PKS+ + R +N +
Sbjct: 193 -MQGQ------LLDNEVLTQIAEKHNKSVAQVILRWDLQHEVVTIPKSIKEHRIIENADI 245
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP 75
F + E+ + + + R P
Sbjct: 246 FDFELSQEDMDKIDALNKDERVGP 269
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 55.2 bits (127), Expect = 8e-07
Identities = 33/117 (28%), Positives = 58/117 (49%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ ++++ KP QI + Q ++ ++N I+ AY P L
Sbjct: 145 AIGVSNFSVSDLKAVMENAKIKPMVNQIRYFIGHTQEDVTAFCQDNGILVEAYSP---LA 201
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
K +++ + IA KY KT+PQ + + ++ G + LPKS H+ QN
Sbjct: 202 TGKI--------LENAEIQKIADKYGKTLPQVCICYCLQKGVLPLPKSTHEAFILQN 250
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 55.2 bits (127), Expect = 8e-07
Identities = 34/143 (23%), Positives = 68/143 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+ NF ++ +++ P Q+E + + + ++N+I AY P GS
Sbjct: 189 NIGVCNFTVTKLNKLLGFAELIPAVCQMEMHPGWRNDRILEFCKKNEIHVTAYSPLGSQE 248
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ I D+ + IA+K NKT Q +++ ++ G V+PKS++ ER ++NI++
Sbjct: 249 GGR-------DLIHDQTVDRIAKKLNKTPGQILVKWGLQRGTSVIPKSLNPERIKENIKV 301
Query: 146 XXFSXTPEEXNLXKSFDTGXRTL 78
+ ++ S R +
Sbjct: 302 FDWVIPEQDFQALNSITDQKRVI 324
>UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 286
Score = 55.2 bits (127), Expect = 8e-07
Identities = 32/119 (26%), Positives = 57/119 (47%), Gaps = 1/119 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + +RI++ +P Q+E + Q EL + I MA+ P G
Sbjct: 137 AIGLSNFNILKTKRILEIARIRPAVNQVEAHPYFPQHELLAFCEKEHIHLMAHQPLGGKP 196
Query: 326 PSKAQPDAP-PPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
P A P + D ++ IA + T Q L + ++ G ++PK+ ++ R +N+
Sbjct: 197 VGVVAPHADIPGPLFDTKIAQIAAQTGMTPAQVILSWAVQRGTSIIPKTSNESRLSENL 255
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 54.8 bits (126), Expect = 1e-06
Identities = 33/124 (26%), Positives = 63/124 (50%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ +++ P Q+E + Q +L + + + AY P GS
Sbjct: 154 AIGVSNFSTKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPG 213
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + D + + L +A+K K+ Q ALR+ +++G VLPKS ++ R ++N +
Sbjct: 214 TTWLKSDV----LKNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNV 269
Query: 146 XXFS 135
+S
Sbjct: 270 FDWS 273
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 54.8 bits (126), Expect = 1e-06
Identities = 35/129 (27%), Positives = 65/129 (50%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF ++ R++ P Q+E N+ Q ++ + E +V AY P G+
Sbjct: 177 SIGVSNFSAAKMSRLLALAAVPPAVNQVEMNVGWRQEKVREVCGEGGVVVAAYSPLGA-H 235
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ DA ++ L +A KT+ Q ALR+L E G ++ +S ++ R +QN+ +
Sbjct: 236 GAHWGSDAV---MNSGVLHDVAAARCKTIAQVALRWLYEQGVCMVARSFNEGRMKQNMDI 292
Query: 146 XXFSXTPEE 120
+ + ++
Sbjct: 293 FDWELSDQD 301
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 54.8 bits (126), Expect = 1e-06
Identities = 37/129 (28%), Positives = 59/129 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
S+G+SNF ++ + P Q+E + Q +L K EN+I AY GS
Sbjct: 145 SVGVSNFEICHLEELKKDSNVVPAVNQVEYHPHFHQDDLVKYCNENNIHFQAYSSLGS-- 202
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P+ + + P I + +AQKYN +P L F G VLP++ + E N ++
Sbjct: 203 PTYRKQLSEEPLIKE-----LAQKYNVEIPVLLLGFAYCQGISVLPRTTNPEHVATNFKV 257
Query: 146 XXFSXTPEE 120
+ T E+
Sbjct: 258 TKLAITQED 266
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 42.3 bits (95), Expect(2) = 1e-06
Identities = 22/58 (37%), Positives = 37/58 (63%)
Frame = -2
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
S ++P APP + + L+ IA++ N T Q AL++ + G V+PKS H+E ++N+Q
Sbjct: 261 SSSKPKAPP-LLQNPILIDIAEERNCTPAQVALKWNMGRGISVIPKSSHEEWIKENLQ 317
Score = 31.9 bits (69), Expect(2) = 1e-06
Identities = 18/69 (26%), Positives = 31/69 (44%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF Q++ ++ +G P Q+E + Q + I AY P G+
Sbjct: 172 NIGVSNFSPLQLKNVVSTG-TIPYMHQMELHPYLQQSAWVATHKALGIKMTAYSPLGNTN 230
Query: 326 PSKAQPDAP 300
P+ +P
Sbjct: 231 PTYHSSTSP 239
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 54.4 bits (125), Expect = 1e-06
Identities = 34/123 (27%), Positives = 57/123 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
S+G+SNF ++ + +G P QIE N Q E+ K ++ I Y P
Sbjct: 139 SVGVSNFGVHHLEELRKAGCRTPAINQIEINPFWRQEEIIKYCNKHGITVEGYAPVFR-- 196
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D LV ++++Y KTV Q +R+ ++ + +PKS + ER +N Q+
Sbjct: 197 ---------GCKFDHPVLVEMSERYGKTVAQIMIRWSVQKQYITIPKSSNPERILENAQV 247
Query: 146 XXF 138
F
Sbjct: 248 FDF 250
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 54.0 bits (124), Expect = 2e-06
Identities = 39/139 (28%), Positives = 59/139 (42%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ + P QIE N Q R+ + A+ PF
Sbjct: 131 AIGVSNFSPDRVIDLAAFNEVTPQVNQIEVNPFQQQTANLAILRKEGVAIEAWAPF---- 186
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
++ + D ++ L I KY K+ Q LR+L+E +VL KSV ER QN+ +
Sbjct: 187 -AEGKNDI----FNNPVLTKIGAKYGKSAAQVILRWLVEQDIIVLAKSVKPERMAQNLAI 241
Query: 146 XXFSXTPEEXNLXKSFDTG 90
F T + D G
Sbjct: 242 FDFELTEADKEEIAGLDQG 260
>UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Bacteroides fragilis|Rep: 2,5-diketo-D-gluconic acid
reductase - Bacteroides fragilis
Length = 298
Score = 54.0 bits (124), Expect = 2e-06
Identities = 40/146 (27%), Positives = 66/146 (45%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SNF ++++ G E P QI + + E + N I M Y P L
Sbjct: 158 IGVSNFHINHLEKLKSIG-ECPSINQIYVSPLSIKHEDLEYSINNAIQLMTYSPLMDLVH 216
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
+ ++D L+ +A+KY KT Q LR+ I+ G + LP++ + R N +L
Sbjct: 217 GQ---------LNDNILMPLAEKYRKTKHQVILRWNIDRGCMPLPRTTNPNRLLGNFELF 267
Query: 143 XFSXTPEEXNLXKSFDTGXRTLPQTK 66
F T EE + + + L ++K
Sbjct: 268 DFKLTEEEIEAISAMNRDLQFLVESK 293
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 54.0 bits (124), Expect = 2e-06
Identities = 38/138 (27%), Positives = 64/138 (46%), Gaps = 1/138 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEK-PXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
+IG+SNF IQ ++DS + P QIE + Q ++ I AY P
Sbjct: 135 AIGVSNFGPHHIQELLDSHPKIIPCVNQIELHPFCSQQKVVDYCESKGIQLAAYAPL--- 191
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
+ +++L++IA KYNK+ Q +R+ ++ G +VLPKS R ++N
Sbjct: 192 --------VHGEKFGNKQLLAIASKYNKSEAQIMIRYCLQRGFIVLPKSSTPRRIKENGD 243
Query: 149 LXXFSXTPEEXNLXKSFD 96
+ F + E+ + D
Sbjct: 244 VFDFEISKEDMEKLYNLD 261
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 53.6 bits (123), Expect = 2e-06
Identities = 36/132 (27%), Positives = 59/132 (44%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+ NF ++R+ E P QIE + Q + K +E+ I ++ P
Sbjct: 137 SIGVCNFLPEHLERLKQETGELPTINQIELHPFFNQEDQRKWHQEHQIATESWSPLARTN 196
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+D L +A +N+TV Q LR+ +L A+ +PKS R +NI +
Sbjct: 197 DV----------LDHPVLQKLASNHNRTVSQIILRWHYQLDAIAIPKSATPSRQLENISI 246
Query: 146 XXFSXTPEEXNL 111
F + EE ++
Sbjct: 247 FDFELSDEEMSI 258
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 53.6 bits (123), Expect = 2e-06
Identities = 35/138 (25%), Positives = 66/138 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF I+R+I+ P Q+E + Q ++ E I +Y PFGS
Sbjct: 135 SIGVSNFTCQHIERLIEDTGVVPAVNQLELHPHFQQCDVRDYHHEAGIAIQSYSPFGSNG 194
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + + ++ +A++++ + Q LR+ ++ G LP++ + R +N+ +
Sbjct: 195 AAV---------LRNAVVMVLARRHDHSPAQIVLRWHLQQGLTPLPRTTNGARFSENVDV 245
Query: 146 XXFSXTPEEXNLXKSFDT 93
F + EE L S +T
Sbjct: 246 WDFELSEEEMKLLASLNT 263
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 53.6 bits (123), Expect = 2e-06
Identities = 37/142 (26%), Positives = 66/142 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ ++++ P QIE + Q EL + I A+ P G
Sbjct: 153 AIGVSNFQPAHLEHLLETAEVVPAVNQIELHPWLQQDELRQLHDRLGIRTEAWSPLG--- 209
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ Q A P ++ +A + ++ Q LR+ ++LG VV+PK+ R +N+ +
Sbjct: 210 --RGQVLADPV------VLELAAAHRRSAAQIILRWHVQLGNVVIPKASSYARIRENLDV 261
Query: 146 XXFSXTPEEXNLXKSFDTGXRT 81
F+ P E + + G RT
Sbjct: 262 FGFTLDPAEMAALAALERGHRT 283
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 53.6 bits (123), Expect = 2e-06
Identities = 39/117 (33%), Positives = 55/117 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF +I ++D P Q+E + Q +L K EN+I Y P G
Sbjct: 155 SIGVSNFSSKKIFDLLDFASVSPSVNQVEMHPLWRQRKLRKVCEENNIHVSGYSPLGG-- 212
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
P I+ + SIA K+N T Q ALR+ + GA V+ KS + R +N
Sbjct: 213 PGNCWGSTAV--IEHPIIKSIALKHNATPAQVALRWGMSKGASVIVKSFNGARMIEN 267
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 53.6 bits (123), Expect = 2e-06
Identities = 35/121 (28%), Positives = 61/121 (50%), Gaps = 1/121 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRII-DSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
SIG+SN+ ++ ++ D P Q+E + QPEL + R++ I AY GS
Sbjct: 188 SIGVSNYTVKHLKEMLADCKGIVPAVNQVEWHPYYYQPELLEYCRQHGIFLQAYSSLGSS 247
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
++ + +DE + S+A+ KT Q LR+ IE +LPK+ ++ ++N+
Sbjct: 248 NTAELR--------EDETVQSVAKSLQKTPVQVLLRWAIEQEVGILPKARSRDHIQENVG 299
Query: 149 L 147
L
Sbjct: 300 L 300
>UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 283
Score = 53.6 bits (123), Expect = 2e-06
Identities = 38/138 (27%), Positives = 65/138 (47%), Gaps = 1/138 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
S+G+SN+ +Q + S + P QIE + Q ++ K + +DI AY P
Sbjct: 142 SVGVSNYGVKHLQELYASNPKFYPCVNQIELHPFLSQDDIVKYCQSHDIAIEAYSPL--- 198
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
R++DE+LV IA+K N +V Q +R+ ++ G + + KS KE ++
Sbjct: 199 --------THGIRLNDEKLVPIAKKLNISVAQLLIRWSLQKGYIPIIKSTKKEHMLSDLD 250
Query: 149 LXXFSXTPEEXNLXKSFD 96
+ F+ + SFD
Sbjct: 251 VFNFTIPDDVVQELSSFD 268
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 53.6 bits (123), Expect = 2e-06
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ + + P QIE + + EL K + I AY P G
Sbjct: 164 AIGVSNFSIKNLEILAKTSKVTPAVNQIEAHPYLPEHELVKYCKHKSIHVTAYSPLGQYN 223
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
S + D+ L IA+K++ T AL + ++ G V PKS +++R +QNI L
Sbjct: 224 ASIHE---------DKDLNEIAKKHDVTAATVALSWAVQRGTSVAPKSTNEKRMKQNITL 274
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 53.2 bits (122), Expect = 3e-06
Identities = 37/137 (27%), Positives = 60/137 (43%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+ NF + + +G P QIE + Q E R+ IV A+ P G
Sbjct: 142 SIGVCNFYPEALDALKQAG-HTPAVNQIEIHPGFSQAEQRSDNRDRGIVTEAWSPLGQ-- 198
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D + IA ++ +V Q +R+ I+ G VV+P+S ER QN +
Sbjct: 199 ---------GQNLTDPTIAKIAAEHGVSVAQAIIRWHIQRGDVVIPRSSKVERVRQNFDV 249
Query: 146 XXFSXTPEEXNLXKSFD 96
F + +E + ++ D
Sbjct: 250 FGFELSADEVSAIEALD 266
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 53.2 bits (122), Expect = 3e-06
Identities = 37/141 (26%), Positives = 60/141 (42%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + ++ + P Q+E + Q EL RE I AY P G
Sbjct: 139 AIGVSNFLGEHLDTLLPAADVVPAVNQVEIHPTFQQQELAAKCRELGIAVEAYSPLGQ-- 196
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
D + D +A KY+ T Q L + + G +V+PKS +R +N+
Sbjct: 197 ----GADLNATAVKD-----LAGKYDATPAQIVLAWHLAQGTIVIPKSADSKRMRENLGA 247
Query: 146 XXFSXTPEEXNLXKSFDTGXR 84
+P E + + ++G R
Sbjct: 248 VAVELSPAELSEISALESGAR 268
>UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid
reductase; n=5; Pezizomycotina|Rep: Related to 2,
5-diketo-D-gluconic acid reductase - Neurospora crassa
Length = 289
Score = 53.2 bits (122), Expect = 3e-06
Identities = 38/136 (27%), Positives = 59/136 (43%), Gaps = 1/136 (0%)
Frame = -2
Query: 500 GISNFXQXQIQRIIDSGLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
G+SN+ + ++ + + KP QIE + QPE+ + IV AY P
Sbjct: 152 GVSNYGVKHLDEVMSAPFKIKPLVNQIECHPFNTQPEIRAACEKYGIVIEAYAPL----- 206
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
A R+ L ++A+KY T Q +R+ ++ G V LPKS KER +N +
Sbjct: 207 ------ARGMRMKHPVLTAVAKKYGVTPAQVLVRWSVQHGFVTLPKSTKKERLVENADVG 260
Query: 143 XFSXTPEEXNLXKSFD 96
F E+ D
Sbjct: 261 RFELAEEDMEKLDGLD 276
>UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9;
Dikarya|Rep: Aldo-keto reductase, putative - Aspergillus
clavatus
Length = 283
Score = 53.2 bits (122), Expect = 3e-06
Identities = 43/140 (30%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRI-IDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
SIG+SNF I+ + + + P QIE + Q + + N IV AY P +
Sbjct: 143 SIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIDAYCKRNGIVVEAYSPL--V 200
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
KA +D LV +A+KY KT Q +R+ ++ V LPKS ER E N +
Sbjct: 201 RNYKA---------NDPTLVDLAKKYGKTTAQVLIRYALQKHWVPLPKSDTPERIEANTK 251
Query: 149 LXXFSXTPEEXNLXKSFDTG 90
+ F + E+ + + D G
Sbjct: 252 VFDFEISEEDMAVLNALDQG 271
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 52.8 bits (121), Expect = 4e-06
Identities = 36/129 (27%), Positives = 60/129 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + + DSG P Q+E + +L + R+ +IV Y P
Sbjct: 151 AIGVSNFLIPHLNELKDSGGIVPHVNQVEFHPFQQPMKLVEHCRKENIVFEGYCPL---- 206
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+K Q P ++ +A+KY ++ Q +R+ I+ G V +PKS +R +N Q+
Sbjct: 207 -AKGQALTHP------HILELAKKYGRSASQICIRWSIQNGVVTIPKSTKPDRIYENCQV 259
Query: 146 XXFSXTPEE 120
F E
Sbjct: 260 FGFRLEDSE 268
>UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus
tropicalis|Rep: LOC548351 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 248
Score = 52.8 bits (121), Expect = 4e-06
Identities = 37/129 (28%), Positives = 60/129 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + ++ + P Q+E + EL R N+IV Y P
Sbjct: 110 SIGVSNFLIHHLDQLKEDCNMVPHLNQVEYHPFQRPQELVDYCRRNNIVFEGYCPL---- 165
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+K Q ++ + IA+ Y KT Q +R+ I+ G V +PKS +ER ++N ++
Sbjct: 166 -AKGQA------LNHPVIQKIAKNYGKTPAQVCIRWSIQNGIVTIPKSTKEERIQENCEV 218
Query: 146 XXFSXTPEE 120
F E+
Sbjct: 219 FGFVLADED 227
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 52.8 bits (121), Expect = 4e-06
Identities = 38/138 (27%), Positives = 64/138 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF Q+ + + KP QIE N + + + A+ PF
Sbjct: 135 AIGVSNFDIAQLTNLAEFSDIKPMLNQIEVNPFQQNKKDITYFSQYGVQVEAWAPF---- 190
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
++ + D + L IA K++K++ Q LR+L + +V+ KSV ER QN+ +
Sbjct: 191 -AEGKNDL----FSNILLRKIADKHHKSIAQIVLRWLTQRNIIVVAKSVKPERMAQNLDI 245
Query: 146 XXFSXTPEEXNLXKSFDT 93
F T +E ++ DT
Sbjct: 246 FDFKLTHQELAEIETLDT 263
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 52.8 bits (121), Expect = 4e-06
Identities = 36/142 (25%), Positives = 63/142 (44%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF ++ + + P QIE + EL R++ I AY P
Sbjct: 134 SIGVSNFNIHHLEALQKHSVIPPVVNQIEVHPYLQMEELVDFCRKHSIAIQAYSPL---- 189
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
++ + ++ D L S+ KY KT Q LR+ ++ G + + KSV R +N+ +
Sbjct: 190 -TRGE------KLHDPLLRSLGDKYGKTPAQVLLRWSLQKGYICISKSVQLSRIIENVDV 242
Query: 146 XXFSXTPEEXNLXKSFDTGXRT 81
F+ + + + + RT
Sbjct: 243 FNFTISMADMEILDGLEENLRT 264
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 52.8 bits (121), Expect = 4e-06
Identities = 38/129 (29%), Positives = 57/129 (44%), Gaps = 1/129 (0%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SNF + R D Q++ + Q +L R +D++ AY P
Sbjct: 134 IGVSNFSPSLLDRARDISSAPIFTDQVQYHPYWDQRKLLDYCRIHDVLLTAYSPL----- 188
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIEL-GAVVLPKSVHKERXEQNIQL 147
A +DD LV I KY K+ Q ALR+L++ G +PK+ +E E N+ +
Sbjct: 189 ------ARGGVLDDPALVQIGNKYGKSPAQVALRWLVQQDGVAAIPKASSREHLEANLAV 242
Query: 146 XXFSXTPEE 120
F T E
Sbjct: 243 FDFELTDAE 251
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 52.8 bits (121), Expect = 4e-06
Identities = 35/120 (29%), Positives = 58/120 (48%), Gaps = 2/120 (1%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SNF ++RI+ KP Q+E + Q E + ++ I AY PFG+
Sbjct: 164 IGLSNFNDTNLERILKVAKVKPAVHQMELHPFLPQTEFVEKHKKLGIHVTAYSPFGN--Q 221
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNK--TVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
+ P I+ E + IA+ + T A+ + I G V+PKSV+++R + N +
Sbjct: 222 NTIYESKIPKLIEHETIQKIAKSKGEGVTGATIAVSWAITRGTSVIPKSVNEQRIKSNFK 281
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 52.4 bits (120), Expect = 6e-06
Identities = 35/117 (29%), Positives = 57/117 (48%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SN+ ++++++ KP QIE + EL + +NDI+ AY P GS
Sbjct: 173 AIGVSNWTIPGLKQLLEFARIKPAVNQIEIHPFLPNTELVEFCFQNDILPEAYSPLGS-- 230
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
P D+ L ++A + ++ Q L + ++ G VVLPKS R E N
Sbjct: 231 -QNQVPTTGERVRDNPTLNAVADRRGSSLAQVLLAWGLKRGYVVLPKSSTPSRIESN 286
>UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase family;
n=1; Mycoplasma penetrans|Rep: Oxidoreductase-aldo/keto
reductase family - Mycoplasma penetrans
Length = 299
Score = 52.0 bits (119), Expect = 7e-06
Identities = 35/137 (25%), Positives = 64/137 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
S+G+SN+ +I + KP +Q E ++ + E+ +I A+ PFG
Sbjct: 162 SVGLSNWYIKEINSFLPQINIKPSLIQNEIHIYYQEKEVVPYMHNLNIAMQAWYPFGGRG 221
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + + P +VSIA+ +NKT Q R+L++ G + + S + ++NI +
Sbjct: 222 HTFSVLNNPT-------IVSIAKDHNKTSAQIISRWLLQRGIITIVGSSNPIHIKENISV 274
Query: 146 XXFSXTPEEXNLXKSFD 96
F + +E L S D
Sbjct: 275 FDFELSNQEMELIASLD 291
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 52.0 bits (119), Expect = 7e-06
Identities = 36/133 (27%), Positives = 60/133 (45%), Gaps = 5/133 (3%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEK---PXALQIEXN--LXXXQPELFKXXRENDIVXMAYXPF 339
IG+SNF + ++R P QIE + L P + K +ENDI+ AY P
Sbjct: 168 IGVSNFSKEHLERTFKVAGNPDFYPKVNQIEFHPYLQNQSPGIIKFAQENDILIEAYGPL 227
Query: 338 GSLXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQ 159
+L K E + +A+KY KT Q LR+ ++ + + S +R Q
Sbjct: 228 STLFRIKQNGVDVEDHPLKELIPKLAEKYGKTDAQILLRYTLQKKILPITTSSKLDRIRQ 287
Query: 158 NIQLXXFSXTPEE 120
++++ F + E+
Sbjct: 288 SLEVYNFEISDED 300
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 50.8 bits (116), Expect = 2e-05
Identities = 37/144 (25%), Positives = 65/144 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ ++ P Q+E + Q E+ ++DI A+ P
Sbjct: 140 AIGVSNFQVHHLEDLLSYAKVVPVINQVELHPKLDQKEVRDFCEKHDIKVQAWSPL---- 195
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ Q + +E +++IA+ +NK+ Q LR+ I+ ++ KSVHKER N +
Sbjct: 196 -MQGQ------LLSNETILAIAENHNKSAAQVILRWDIQQDILLAVKSVHKERMISNAAV 248
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLP 75
F + EE + R P
Sbjct: 249 FDFELSAEEMAQINQLNESLRVGP 272
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 50.8 bits (116), Expect = 2e-05
Identities = 36/129 (27%), Positives = 60/129 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF I+ + P Q+E + Q E I+ MA+ P G
Sbjct: 154 SIGVSNFLPKHIETLRRETGVIPVINQVELHPYFNQAEQRAYDESQQIITMAWSPLGR-- 211
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+KA +DD L IAQ+ ++TV Q LR+ +++G + +PK+ + N +
Sbjct: 212 -AKAI-------LDDAVLKQIAQETSRTVVQVVLRWQVQMGVIPIPKAASDQNQMANQAI 263
Query: 146 XXFSXTPEE 120
FS + ++
Sbjct: 264 FDFSLSDDQ 272
>UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3;
Pezizomycotina|Rep: Aldo-keto reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 283
Score = 50.8 bits (116), Expect = 2e-05
Identities = 42/140 (30%), Positives = 62/140 (44%), Gaps = 1/140 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRI-IDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
SIG+SNF I+ + + + P QIE + Q + + N IV AY P +
Sbjct: 143 SIGVSNFGVKHIEEMKAYAKVWPPHVNQIELHPWCQQRVIEAYCKRNGIVVEAYSPL--V 200
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
KA +D LV +A+KY +T Q +R+ ++ G V LPKS ER N
Sbjct: 201 RNYKA---------NDPTLVDVAKKYERTTAQILIRYALQKGWVPLPKSDTPERIVANAN 251
Query: 149 LXXFSXTPEEXNLXKSFDTG 90
+ F E+ + D G
Sbjct: 252 VFDFEIGEEDLAVLNGLDQG 271
>UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 289
Score = 50.4 bits (115), Expect = 2e-05
Identities = 36/129 (27%), Positives = 59/129 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF +I + KP QIE N + E + +V A+ PF
Sbjct: 133 NIGVSNFWDNRIIDLCFFNQIKPMVNQIEINPFHQRIEDRFYNDKYKVVSQAWAPFA--- 189
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + LV I +KYNKT Q LR+L++ V L K+V++ R ++N +
Sbjct: 190 ------EGKNGLFTNPTLVEIGKKYNKTPAQVILRWLVQSNVVALCKTVNESRMKENFDI 243
Query: 146 XXFSXTPEE 120
F + ++
Sbjct: 244 FDFELSKQD 252
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 50.4 bits (115), Expect = 2e-05
Identities = 34/152 (22%), Positives = 61/152 (40%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + +++ +P QIE Q ++ I A+ P G
Sbjct: 158 SIGVSNFNPHHLDELLEYARIRPVVNQIEIEPYMTQHDVVGYTFRKGIQVEAWGPLGQGV 217
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+DD + IA ++ K+ Q LR+ ++ G V +P+ + ++NI++
Sbjct: 218 TGV---------LDDPAIGEIAARHGKSAAQVILRWHMQRGLVTIPRCDNDAYTDENIRI 268
Query: 146 XXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHP 51
F +P E + + R Q P
Sbjct: 269 FDFELSPSEMEIITGLNRNQRAYEQNDPDNFP 300
>UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22;
Pezizomycotina|Rep: Aldehyde reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 295
Score = 50.4 bits (115), Expect = 2e-05
Identities = 41/143 (28%), Positives = 75/143 (52%), Gaps = 4/143 (2%)
Frame = -2
Query: 506 SIGISNFXQXQIQRI---IDSGLEKPXAL-QIEXNLXXXQPELFKXXRENDIVXMAYXPF 339
SIG+SN+ ++ + I+SG+ ++ Q E + + ++ ++ ++V AY P
Sbjct: 152 SIGVSNYGIHHLEELEEYINSGVGGEISVGQYEIHPWCAREDIVAWLKKRNVVIEAYSPL 211
Query: 338 GSLXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQ 159
+AQ R+D+ L ++A+K+NKT Q +R+ ++ G V LPKSV R +
Sbjct: 212 -----VQAQ------RLDEPVLQNLAKKHNKTGAQILIRWSLQKGYVPLPKSVTDSRIVE 260
Query: 158 NIQLXXFSXTPEEXNLXKSFDTG 90
N Q+ F + E+ +S +TG
Sbjct: 261 NTQVFDFELSGED---MESLNTG 280
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/139 (25%), Positives = 61/139 (43%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SN+ + ++ + + P LQ+E + +L + +V A+ P L
Sbjct: 150 AIGLSNYEREHVEAVREVATVAPHVLQVESHPFFPNADLRAYAQGLGMVFEAWSP---LA 206
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+A + D LV I + Q LR+ ++ G VV PK++ +ER N +
Sbjct: 207 RGRA--------VTDPTLVEIGAELGVGPTQVTLRWALDRGHVVFPKTLSRERMAANFDV 258
Query: 146 XXFSXTPEEXNLXKSFDTG 90
FS PE+ + D G
Sbjct: 259 FSFSLDPEQTARIDALDAG 277
>UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 302
Score = 50.0 bits (114), Expect = 3e-05
Identities = 35/129 (27%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SNF ++++ + QIE + EL + ++ND+ AY P L
Sbjct: 143 IGVSNFSIKELKQAMRLSDAPIATNQIEYHPYWGDEELVRFCQDNDVTVTAYSP---LAE 199
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIEL-GAVVLPKSVHKERXEQNIQL 147
+A ++D+ L SI +Y K+ Q ++R+LI+ V +PK+ + E NI +
Sbjct: 200 GRA--------VEDDVLRSIGDRYGKSAAQVSIRWLIQQENVVTIPKAATPKHIEANIDV 251
Query: 146 XXFSXTPEE 120
F T +
Sbjct: 252 FDFELTDRD 260
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 50.0 bits (114), Expect = 3e-05
Identities = 36/124 (29%), Positives = 53/124 (42%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + II++ P QIE + QPEL + +I AY P G+
Sbjct: 157 AIGVSNFDAKMVDAIIEATGVTPSVNQIERHPLLLQPELIAHHKAKNIHITAYSPLGN-- 214
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P + + IA+K T Q + + I G V+PKSV R +N +
Sbjct: 215 ----NTVGAPLLVQHPEIKRIAEKNGCTPAQVLIAWAIVGGHSVIPKSVTPSRIGENFKQ 270
Query: 146 XXFS 135
S
Sbjct: 271 VSLS 274
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 49.6 bits (113), Expect = 4e-05
Identities = 31/129 (24%), Positives = 60/129 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+S+ ++ I ++ KP +Q+E + + EL + + N IV +A+ P G
Sbjct: 164 AIGLSDISMDRLAPIYEAARIKPAVVQVESHPYLPETELLEFCKRNGIVLLAFAPLGH-- 221
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P ++D + S++++ KT Q L + ++ G +L R ++N +
Sbjct: 222 ------GMRPGLLEDPVITSVSERVGKTAAQVLLSWAVQRGTALLTTPRSAARAKENFDI 275
Query: 146 XXFSXTPEE 120
S PEE
Sbjct: 276 ---SPLPEE 281
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 49.6 bits (113), Expect = 4e-05
Identities = 38/142 (26%), Positives = 64/142 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + ++ KP Q+E + Q +L + + +I +AY P G
Sbjct: 174 SIGVSNFNVQNLVDLLTYAKIKPVVNQVEIHPYLTQFKLQEYCDKYEIKLVAYSPLG--- 230
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + D +I L SIA KY K+V ++L + G +PKS + R +N +
Sbjct: 231 --QGKCDFFSNKI----LKSIAGKYKKSVANVIFKWLNQRGIAAIPKSGNHSRIIENFNI 284
Query: 146 XXFSXTPEEXNLXKSFDTGXRT 81
F + ++ S + RT
Sbjct: 285 FDFQLSNDDIEKINSLNANIRT 306
>UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 276
Score = 49.6 bits (113), Expect = 4e-05
Identities = 32/136 (23%), Positives = 59/136 (43%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SN+ ++ II GL P Q+E + +P + I+ A+ P
Sbjct: 137 IGVSNYNIHHLEEIISLGLPLPAINQVEFSAFNNRPTFLSYCFNHGILVQAFSPL----- 191
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
R+ D RL+ ++ KYNKT LR+ ++ G + K+ +N++
Sbjct: 192 ------TRGYRLSDIRLLDLSLKYNKTPANILLRYCLQKGVSPIFKASSFVHIHENVKAE 245
Query: 143 XFSXTPEEXNLXKSFD 96
F P + ++ ++D
Sbjct: 246 QFMLDPSDMDVMDTWD 261
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 49.2 bits (112), Expect = 5e-05
Identities = 43/153 (28%), Positives = 69/153 (45%), Gaps = 1/153 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
SIG+SNF +Q ++ + + P Q+E + Q EL K E I AY G+
Sbjct: 152 SIGVSNFTIKHLQELLQNCKDILPAVNQVELHPHYRQEELIKYCNEKGIHIQAYSSLGTS 211
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
+ + ++ IA + N + + L + ++ G V+PK+V+KE + NIQ
Sbjct: 212 GNINL--------LRNPIVLKIASQLNVSSARLLLNWALQQGIGVIPKAVNKEHIKDNIQ 263
Query: 149 LXXFSXTPEEXNLXKSFDTGXRTLPQTKWSKHP 51
L F E N+ S LPQ K++ P
Sbjct: 264 L-DFLIDEESMNILFS-------LPQIKYAWDP 288
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 49.2 bits (112), Expect = 5e-05
Identities = 34/141 (24%), Positives = 59/141 (41%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SN+ ++ ++ + P Q+E + Q +L +E I AY P G
Sbjct: 158 AIGVSNYSIKTLEELLKTAKVVPAVNQVELHPFLAQSKLLAYCKEKGIAVTAYTPTGYQT 217
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D +V +A KY + Q L + + G PKS ++ R ++N+ L
Sbjct: 218 V-----------LTDPTIVELAGKYGVSPAQIVLAWHLSRGVAAAPKSANESRQKENLNL 266
Query: 146 XXFSXTPEEXNLXKSFDTGXR 84
PE+ + D G R
Sbjct: 267 PFLQ--PEDVAKISALDRGQR 285
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 49.2 bits (112), Expect = 5e-05
Identities = 33/139 (23%), Positives = 60/139 (43%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + ++ +ID P Q+E + Q L E+ I ++ P
Sbjct: 136 SIGVSNFTEPMLKTLIDETGVTPAVNQVELHPYFPQAALRAFHDEHGIRTESWSPLARRS 195
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ ++ L +A Y T Q LR+ ++LG+ +PKS +R +N +
Sbjct: 196 EL----------LTEQLLQELAVVYGVTPTQVVLRWHVQLGSTPIPKSADPDRQRENADV 245
Query: 146 XXFSXTPEEXNLXKSFDTG 90
F+ T ++ + + G
Sbjct: 246 FGFALTADQVDAISGLERG 264
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 48.8 bits (111), Expect = 7e-05
Identities = 35/137 (25%), Positives = 56/137 (40%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG SNF + + +G P QI+ + +P++ IV ++ P G
Sbjct: 139 AIGTSNFLPHHLNDLFAAGFV-PHVNQIQLDPYHLRPDITAIHAAKGIVTESWSPIGRAG 197
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
A P + IA+ + KT Q LR+ ++ G V PKS ER QN+ +
Sbjct: 198 EMLADP----------AITRIAEAHGKTPAQIVLRWQVQSGFVPAPKSADPERQAQNLDV 247
Query: 146 XXFSXTPEEXNLXKSFD 96
F+ T + D
Sbjct: 248 FGFALTESDMAALNGLD 264
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 48.8 bits (111), Expect = 7e-05
Identities = 37/131 (28%), Positives = 57/131 (43%), Gaps = 2/131 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXN--LXXXQPELFKXXRENDIVXMAYXPFGS 333
SIG+SNF I+ I+ KP QIE N L P + ++N+I AY P G
Sbjct: 154 SIGVSNFSVKNIEEILKIAGIKPQVNQIEFNAFLQNQTPGIVNYCQKNNIQLEAYSPLG- 212
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
P + +P+ + +A KY KT Q L ++ G + + S +R
Sbjct: 213 --PLQKRPENSNELPFYNYIDELASKYGKTDSQILLNWVYNRGILPITTSSKTQRIIDAQ 270
Query: 152 QLXXFSXTPEE 120
+ F+ T +E
Sbjct: 271 NIFSFNLTKDE 281
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 48.4 bits (110), Expect = 9e-05
Identities = 30/129 (23%), Positives = 57/129 (44%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SN+ + RI+ + P +Q E ++ + R A+ P G
Sbjct: 170 AIGLSNYHRKTFNRIMQAATITPAVVQNEVHIYNQDKQTKAFLRNYGTQMEAWYPLGGR- 228
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D +VS+A+KY K+ Q LR+ ++ G + +P S + +NI +
Sbjct: 229 -NSYGNGGKDVLFADPTIVSLAKKYAKSPAQVLLRWQLQAGNIAIPGSSNPAHIRENIDI 287
Query: 146 XXFSXTPEE 120
F+ + +E
Sbjct: 288 FDFALSDDE 296
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 48.4 bits (110), Expect = 9e-05
Identities = 35/137 (25%), Positives = 62/137 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF + ++RIID P QIE + Q ++ K + IV ++ P G
Sbjct: 132 SIGVSNFREEDLKRIIDETGVTPALNQIELHPSFQQRDMRKVHEDLGIVTQSWSPLGQ-- 189
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
K + +E + +IA++ + LR+ I+ G +PK+ ++ E N +
Sbjct: 190 -GKG--------MSNEVIEAIAEETGQPETAVILRWHIQHGLCPIPKASSRDHIEANFKA 240
Query: 146 XXFSXTPEEXNLXKSFD 96
F + E+ + D
Sbjct: 241 LSFELSDEQMGRIDALD 257
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 48.4 bits (110), Expect = 9e-05
Identities = 38/123 (30%), Positives = 57/123 (46%), Gaps = 1/123 (0%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IGISN+ Q Q + + E A+Q E + Q + K R D++ +Y P G
Sbjct: 132 IGISNYNQAQFLEAVSASEEPLAAIQCEYHPMLDQDPILKTARGFDMMFTSYSPLGR--- 188
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRF-LIELGAVVLPKSVHKERXEQNIQL 147
+A + P I ERL A+++ KT Q LR+ L + +PK+ K EQN +
Sbjct: 189 GEAMSN---PAI--ERL---AEQHGKTPAQIILRWHLQQANVAAIPKATSKAHIEQNFDI 240
Query: 146 XXF 138
F
Sbjct: 241 FDF 243
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 47.6 bits (108), Expect = 2e-04
Identities = 33/142 (23%), Positives = 61/142 (42%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
+G+SNF I ++ KP QIE ++ Q L + ++ +I +A+ P
Sbjct: 152 LGVSNFNCQMIIDLLAYCKIKPLVNQIELHVFNQQKNLVEFLKKVNIYPVAFSPMAKYNE 211
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
+ +E L IAQK N +V Q + F+ VV+P++ ER + N
Sbjct: 212 V----------VKNETLNQIAQKQNASVAQVMIAFMYHQDVVVIPRTAKIERLQHNFDAQ 261
Query: 143 XFSXTPEEXNLXKSFDTGXRTL 78
+ E+ ++ ++ R +
Sbjct: 262 KLQFSEEDIQTLRNLNSNTRVV 283
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 47.6 bits (108), Expect = 2e-04
Identities = 41/152 (26%), Positives = 66/152 (43%), Gaps = 21/152 (13%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFG--- 336
+IG+SNF QI+ ++ P Q++ + Q EL K + I A+ P G
Sbjct: 163 AIGVSNFGVQQIKELLKFAKIVPAVNQVKLHPFWRQDELVKFCQSKGIHVSAHTPLGVPA 222
Query: 335 -----SLXPSKAQPDAPPPRIDDER-------------LVSIAQKYNKTVPQXALRFLIE 210
S S + + PRI R + IA ++ KT Q LR+ ++
Sbjct: 223 SGPGPSDSGSGGEDEPGTPRISFRRSRSVHGPMLKLSVVAEIADRHKKTPEQVILRWGLQ 282
Query: 209 LGAVVLPKSVHKERXEQNIQLXXFSXTPEEXN 114
G VLP S+ +R +NI + +S + +E N
Sbjct: 283 RGTSVLPCSLKADRIRKNIDIFSWSLSDDECN 314
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 47.6 bits (108), Expect = 2e-04
Identities = 32/132 (24%), Positives = 64/132 (48%), Gaps = 3/132 (2%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEK-PXALQIEXN--LXXXQPELFKXXRENDIVXMAYXPFG 336
+IG+SNF ++ I+D+ + P QIE + L P + + ++ I+ AY P G
Sbjct: 156 NIGVSNFTIENLKSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLG 215
Query: 335 SLXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
+ + P P D+ L +++KY + Q LR++++ G + + + +ER
Sbjct: 216 PITQGR-----PGPL--DKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDV 268
Query: 155 IQLXXFSXTPEE 120
+++ F E+
Sbjct: 269 LEIFDFELDKED 280
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 47.2 bits (107), Expect = 2e-04
Identities = 34/124 (27%), Positives = 59/124 (47%), Gaps = 6/124 (4%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF + +I+ ++ P Q+E + Q + RE I + + P G++
Sbjct: 184 AIGVSNFSKGEIETLLRETSTVPAVHQMEVHPYLQQKGFNEWLREKGIHVVQFSPLGNMN 243
Query: 326 PSKAQPD-----APPPRIDDERLVS-IAQKYNKTVPQXALRFLIELGAVVLPKSVHKERX 165
Q A R+ D+ ++ I QKY K+ Q L + I G V+PK+V +
Sbjct: 244 DFYRQAGWSKEIAHMMRVIDQPILKEIGQKYGKSPVQVVLAWGINSGRSVIPKTVIDWQI 303
Query: 164 EQNI 153
E+N+
Sbjct: 304 EENL 307
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 46.8 bits (106), Expect = 3e-04
Identities = 36/139 (25%), Positives = 62/139 (44%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF ++ IID+ P QI+ + + E R IV A+ P G
Sbjct: 145 AIGVSNFKPAHLKDIIDATGVVPDVNQIQLSPDLARTEPRAVHRLLGIVTEAWSPIGRSS 204
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+A P ++ IAQ+ +K+ Q LR+ ++ V +P++ ++N+ +
Sbjct: 205 GLRANP----------LIIEIAQRLDKSPAQVLLRWHVQQDIVPIPQASDPLWLKENLSV 254
Query: 146 XXFSXTPEEXNLXKSFDTG 90
FS T E + D G
Sbjct: 255 FDFSLTAGEMASIRKLDRG 273
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 46.8 bits (106), Expect = 3e-04
Identities = 40/132 (30%), Positives = 68/132 (51%), Gaps = 1/132 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
SIG+SN+ ++++++ + + KP QIE + Q +L K +N + AY P GS
Sbjct: 169 SIGVSNYSIPKLRKLLAAVRKHKPVVNQIEYHPLLPQQDLVKYCYDNGVHISAYSPVGS- 227
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
AP ++ + + +A KY+ +V + A + I G VLP+S + ER + I+
Sbjct: 228 ------NGAPVLKL--QLINELASKYDVSVNEIANAYHILQGRSVLPRSSNLERIKSIIR 279
Query: 149 LXXFSXTPEEXN 114
L + T EE N
Sbjct: 280 LP--NLTTEELN 289
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 46.4 bits (105), Expect = 4e-04
Identities = 32/124 (25%), Positives = 59/124 (47%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+ NF +++++ P QIE + Q ++ E+DI A+ P L
Sbjct: 135 AIGVCNFKIHHLEKLMKETKITPQVNQIELHPYFNQQDVQDFCDEHDIKVTAWMP---LM 191
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+K +DD + IA +Y+KT Q LR+ + +++PKS +R ++N +
Sbjct: 192 RNKGL-------LDDPVITDIAHRYDKTPAQIVLRWHLAHNRIIIPKSQTPKRIKENFDI 244
Query: 146 XXFS 135
F+
Sbjct: 245 FDFN 248
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 46.4 bits (105), Expect = 4e-04
Identities = 41/137 (29%), Positives = 65/137 (47%), Gaps = 8/137 (5%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIID--SGLEKPXAL-QIEXNLXXXQ----PELFKXXRENDIVXMAY 348
SIG+SNF +Q + D GL+ P + QIE + +L RE I AY
Sbjct: 166 SIGVSNFLISHLQTLFDIPGGLQYPPVVNQIEYHPYLQHVVEGEDLVAFCREKHIAIAAY 225
Query: 347 XPFGSLXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKER 168
P ++ +KA+P P +A+KY + + A R+ ++ G V L S ++ER
Sbjct: 226 SPLTAI--TKARPGPVDP-----IYTQLAKKYGVSEAEIAFRWCLDQGIVTLTTSSNEER 278
Query: 167 XEQNI-QLXXFSXTPEE 120
+ + +L F TP+E
Sbjct: 279 LKGYLKKLPSFKLTPKE 295
>UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 284
Score = 46.0 bits (104), Expect = 5e-04
Identities = 45/151 (29%), Positives = 68/151 (45%), Gaps = 10/151 (6%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNL---------XXXQPELFKXXRENDIVXMA 351
IG+SNF QI+ K A QIE NL + E+ +EN+I +A
Sbjct: 143 IGVSNFSVDQIKEAQKYTKNKIVANQIEYNLLVRDKGRVTENMESEIIPYCQENNIFIIA 202
Query: 350 YXPFGSLXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLI-ELGAVVLPKSVHK 174
+ P +K + P +I DE +A KY+KT Q A+ +LI + G VV+ KS
Sbjct: 203 WRPL-----AKGKLAKPGFKILDE----LADKYHKTQAQIAINWLISKKGIVVISKSTKV 253
Query: 173 ERXEQNIQLXXFSXTPEEXNLXKSFDTGXRT 81
E E+N+ + E+ + + RT
Sbjct: 254 EHLEKNLGAIGWKLRQEDTDRLNNEFINSRT 284
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 46.0 bits (104), Expect = 5e-04
Identities = 36/138 (26%), Positives = 64/138 (46%), Gaps = 2/138 (1%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SNF Q++RI + KP A Q+E N+ L ++I MA+ G P
Sbjct: 153 IGVSNFSIEQLERIWFNCEIKPYANQVECNIYRQFKPLLSYCESHNIYLMAHTTIG--HP 210
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGA--VVLPKSVHKERXEQNIQ 150
P ++D + +A + KT Q L+FL + +++P S++ + + N +
Sbjct: 211 PLKGPFG-TSLLEDPVVKQVASEAKKTSAQICLKFLQQKSKMYILIPMSMNPKNIKSNYE 269
Query: 149 LXXFSXTPEEXNLXKSFD 96
L F+ T ++ + D
Sbjct: 270 L-DFTLTEQQMKKLEELD 286
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 45.6 bits (103), Expect = 7e-04
Identities = 37/133 (27%), Positives = 56/133 (42%), Gaps = 5/133 (3%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SN + ++ KP Q E L + N I AY P G
Sbjct: 150 IGVSNMGTAMLVDLLSYCRIKPFTNQFESQPYFPNDRLIEFCNSNGIYVTAYRPLGG--- 206
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXAL-----RFLIELGAVVLPKSVHKERXEQ 159
+ + DA P + D L +A+K N TV + L R+ V+PKS +ER +Q
Sbjct: 207 -RCRVDAKAP-LTDPALEELAKKANLTVSELILAWHWTRWGTSGTYSVIPKSSDRERQKQ 264
Query: 158 NIQLXXFSXTPEE 120
N++ TP++
Sbjct: 265 NLESVKLRLTPDQ 277
>UniRef50_A6RYK4 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 182
Score = 45.6 bits (103), Expect = 7e-04
Identities = 36/129 (27%), Positives = 59/129 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+ NF ++ II E P QIE + Q EL ++N I A F SL
Sbjct: 36 AIGVCNFAISHLETIIAGASEIPAVNQIEYHAYLQQSELSAYCQKNGIKVEA---FASLA 92
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P + P + + +AQKY + LR+ ++ G V+ S+ +ER + +++
Sbjct: 93 PWIT--EGPAKGV----VAELAQKYGVGETEICLRWCVQKGVPVVTTSLKEERVKGYLKV 146
Query: 146 XXFSXTPEE 120
FS +E
Sbjct: 147 FDFSLEDKE 155
>UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG05425;
n=1; Caenorhabditis briggsae|Rep: Putative
uncharacterized protein CBG05425 - Caenorhabditis
briggsae
Length = 319
Score = 45.2 bits (102), Expect = 9e-04
Identities = 31/127 (24%), Positives = 54/127 (42%)
Frame = -2
Query: 443 KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXPSKAQPDAPPPRIDDERLVSI 264
+P Q+E + + EL + ++N I+ A+ PFG ++D+ + I
Sbjct: 199 EPTVNQVEFHPHFQRKELREFCQKNGILFQAFSPFGR---------GNSALLNDQIMTGI 249
Query: 263 AQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLXXFSXTPEEXNLXKSFDTGXR 84
A+K++ TV L ++++ G V KS ER +N + T EE K D
Sbjct: 250 AEKHHTTVSSVILTWIVQSGNGVAVKSKSIERVSENFKSTTLQLTDEEMVKIKELDLSTP 309
Query: 83 TLPQTKW 63
+ W
Sbjct: 310 YVEDRGW 316
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 45.2 bits (102), Expect = 9e-04
Identities = 34/133 (25%), Positives = 64/133 (48%), Gaps = 2/133 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDS-GLE-KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
SIG+SN+ + ++ S L+ KP Q+E + Q +L + + N I+ +Y GS
Sbjct: 165 SIGVSNYTINHLTELLSSPNLQIKPAINQVEFHPLNFQKDLLEFCKNNKIILESY---GS 221
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
L + +++E + A+K +T Q LR+ +E V+PK+ + R +N
Sbjct: 222 LAGGRL--------LNNESVKEFAKKVGRTPSQLLLRYCLEHNCPVIPKTENVHRLIENQ 273
Query: 152 QLXXFSXTPEEXN 114
+ F+ + + N
Sbjct: 274 MILDFTLSDDIVN 286
>UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1;
Sclerotinia sclerotiorum 1980|Rep: Putative
uncharacterized protein - Sclerotinia sclerotiorum 1980
Length = 326
Score = 45.2 bits (102), Expect = 9e-04
Identities = 23/58 (39%), Positives = 33/58 (56%)
Frame = -2
Query: 293 RIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLXXFSXTPEE 120
R D + L + +KYNKT Q LR+ ++ G V LPK+V R ++N + F T EE
Sbjct: 246 RHDSKLLQPLTKKYNKTPAQILLRWSLQKGFVPLPKTVTPGRIKENADIFDFELTAEE 303
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 44.8 bits (101), Expect = 0.001
Identities = 30/120 (25%), Positives = 54/120 (45%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF +++ ++ P QIE + QP+L + + I+ AY P G+
Sbjct: 154 AIGVSNFNIRRLEELLGQVSVVPAVNQIEAHPYLQQPDLLQFCQSKGILIEAYSPLGN-- 211
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P +DD + +A + + + ++ G VVL KSV R N+++
Sbjct: 212 ----NQTGEPRTVDDPLVHRVAGELSLDPGPLLASWGVQRGTVVLSKSVTPARIAANLRV 267
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 44.4 bits (100), Expect = 0.002
Identities = 35/141 (24%), Positives = 55/141 (39%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SN+ I+ ++ S P LQIE Q EL E I AY G
Sbjct: 148 AIGVSNYTAKHIRELLASCRVPPAVLQIECQPKLIQRELRDLCMETGIHFQAYSSLGK-- 205
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ + ++ I + +T Q LR+ ++ G VLP+S R +N Q+
Sbjct: 206 ---------GALLREPEVMDIVRHCGRTPAQVLLRWALQQGISVLPRSSQPSRVLENAQV 256
Query: 146 XXFSXTPEEXNLXKSFDTGXR 84
F + + G R
Sbjct: 257 FDFKLNETDMKRLDDLNCGTR 277
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 44.0 bits (99), Expect = 0.002
Identities = 29/128 (22%), Positives = 58/128 (45%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SNF I++ + E Q+E + Q ++ ++ + +AY P +
Sbjct: 132 IGVSNFTVALIEQAVALSPEPLVCNQVEFHPYLDQAKVRAACDQHGLALVAYSP---IAR 188
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
+ + D+ L I + + KT Q LR+L++ +P++ ER +NI++
Sbjct: 189 GRIK--------TDQTLAGIGRAHRKTPAQVCLRWLVQQNVAAIPRTSRIERLSENIEIF 240
Query: 143 XFSXTPEE 120
F + +E
Sbjct: 241 DFELSDDE 248
>UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Picrophilus torridus|Rep: 2,5-diketo-D-gluconic acid
reductase - Picrophilus torridus
Length = 283
Score = 43.6 bits (98), Expect = 0.003
Identities = 36/135 (26%), Positives = 62/135 (45%), Gaps = 4/135 (2%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXAL--QIEXN--LXXXQPELFKXXRENDIVXMAYXPFG 336
IG+SNF +++ + S + K + Q+E N + +PE+ + R+N I +AY P
Sbjct: 129 IGVSNFNVNELKSAM-SAMSKYEIVSNQVEYNPLVRYIEPEISEFCRKNSISIIAYSPL- 186
Query: 335 SLXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
D P D+ IA K N TV Q L +++ +PKS E +N
Sbjct: 187 -----MHGHDIDPISKDESPFNIIANKRNATVRQVILAWILSKNFFAIPKSNVPEHVIEN 241
Query: 155 IQLXXFSXTPEEXNL 111
++ + + EE ++
Sbjct: 242 VKSMNINLSSEETSM 256
>UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula
marismortui|Rep: Oxidoreductase - Haloarcula marismortui
(Halobacterium marismortui)
Length = 264
Score = 43.6 bits (98), Expect = 0.003
Identities = 34/121 (28%), Positives = 57/121 (47%), Gaps = 1/121 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXAL-QIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
++G+SNF Q+ + P A+ QIE + Q ++ + R+ D V A P G
Sbjct: 117 NVGVSNFSAYQLGAA-QHVADVPIAVNQIEYHPWNTQDQVVEFCRDTDTVVEAAAPLGR- 174
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
+K D+ + +++KY+++ Q L++ +E VVLPKS E QN
Sbjct: 175 --TKV--------FADDIIQDLSEKYDRSPAQIVLKWAVENNVVVLPKSSSPEHVRQNFD 224
Query: 149 L 147
L
Sbjct: 225 L 225
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 43.2 bits (97), Expect = 0.003
Identities = 33/126 (26%), Positives = 53/126 (42%), Gaps = 2/126 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEK--PXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
+IG+SNF ++ ++ + K P Q+E + Q EL + E IV AY P G
Sbjct: 163 AIGVSNFSVNNLKDLLAAPTTKVTPAVNQVEFHPLLPQEELIQYCSEKGIVIEAYSPLGG 222
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
P + D + IA+ + + ++ G V LPKSV R N+
Sbjct: 223 ---------ENAPILSDPTVQEIAKANGVEAGHVVISWAVQKGLVTLPKSVTPSRIVGNL 273
Query: 152 QLXXFS 135
++ S
Sbjct: 274 KVLTLS 279
>UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 258
Score = 43.2 bits (97), Expect = 0.003
Identities = 35/130 (26%), Positives = 58/130 (44%), Gaps = 2/130 (1%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXAL-QIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+G+SNF Q+ R ID+ L+ P A Q E + +PEL + RE+ +AY P
Sbjct: 125 VGVSNFEVDQLDRAIDT-LDAPLAAHQTELHPLFYRPELLEHAREHGYTVVAYSPLAGGR 183
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVV-LPKSVHKERXEQNIQ 150
S+ + +V +A+ ++ T A+ + VV +PK+ + N+
Sbjct: 184 VSEI-----------DAVVEVAEAHDATPEAVAIAWATAKEPVVTIPKASSEGHLRANLA 232
Query: 149 LXXFSXTPEE 120
TPEE
Sbjct: 233 AAEIELTPEE 242
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 42.7 bits (96), Expect = 0.005
Identities = 35/135 (25%), Positives = 60/135 (44%), Gaps = 5/135 (3%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEK---PXALQIEXN--LXXXQPELFKXXRENDIVXMAYXPF 339
IGISN ++++ + P QIE + L + + +E+ I+ A+ P
Sbjct: 158 IGISNAAIPHLEKLFAASPSPEYYPVVNQIEFHPFLQNQSKNIVRFCQEHGILVEAFSPL 217
Query: 338 GSLXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQ 159
L + A E L +A+KY KT Q LR+ ++ G + + S + R ++
Sbjct: 218 APLARVETNALA-------ETLKRLAEKYKKTEAQVLLRYTLQRGILPVTTSSKESRLKE 270
Query: 158 NIQLXXFSXTPEEXN 114
++ L F T EE N
Sbjct: 271 SLNLFDFELTDEEVN 285
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 42.7 bits (96), Expect = 0.005
Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 5/133 (3%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXAL--QIEXNLXXXQPE---LFKXXRENDIVXMAYXPF 339
IGISNF +++ + S L K + Q+E N+ + E ++ R+N + +AY P
Sbjct: 137 IGISNFSVKEMKEAM-SALAKYRIVSNQLEYNVATREIEDEGIYDFCRKNGMAIIAYSP- 194
Query: 338 GSLXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQ 159
L K + + E L I +KY K Q AL ++I GA +PK+ +
Sbjct: 195 --LSHGKIFGN----EMILETLTDIGKKYGKRPAQVALNWIIRKGAFPIPKASKPIHMAE 248
Query: 158 NIQLXXFSXTPEE 120
NI+ F+ + E+
Sbjct: 249 NIESTDFTLSDED 261
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 42.3 bits (95), Expect = 0.006
Identities = 36/121 (29%), Positives = 54/121 (44%), Gaps = 1/121 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXAL-QIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
++G+SNF Q+ + E P A+ QIE + +P L E+D V A
Sbjct: 163 NVGVSNFSAYQLS-CANHISEVPIAVNQIEFHPWFQRPNLVDYCHESDTVIEA------- 214
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
A P A DDE + +A+ Y+K+ Q LR+ ++ V LP+S E N
Sbjct: 215 ----AAPLARTEVFDDEVVAELAESYDKSPAQVILRWALDRDVVALPRSSTPEHVRANAD 270
Query: 149 L 147
L
Sbjct: 271 L 271
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 41.9 bits (94), Expect = 0.008
Identities = 39/143 (27%), Positives = 56/143 (39%), Gaps = 3/143 (2%)
Frame = -2
Query: 503 IGISNFXQXQIQ---RIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGS 333
IG+SNF + I R++DS Q+E ++ + + I AY P
Sbjct: 133 IGVSNFTKAMIDESIRLLDS--RTITTNQVECHVYMQNRPIIDYCQNLGIAVTAYSPL-- 188
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
A + D L I + T Q AL FLI G VV+P S + R QN
Sbjct: 189 ---------ARGAVVGDPVLEEIGKARGATSDQIALAFLIAKGHVVIPSSSKRGRIMQNF 239
Query: 152 QLXXFSXTPEEXNLXKSFDTGXR 84
+ + TP E + + G R
Sbjct: 240 EARKITLTPAEIKRIEGLEKGMR 262
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 41.9 bits (94), Expect = 0.008
Identities = 30/121 (24%), Positives = 55/121 (45%), Gaps = 3/121 (2%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
+G SN ++ ++ P ++E + QPELF + I + Y P GS P
Sbjct: 171 LGTSNTTVAKLDLLLRDARIPPALNEMELHPCFQQPELFAHCVRHGIQPVGYSPLGS--P 228
Query: 323 SKAQPDAPPPRI---DDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
S+ + D P + +D +V IA+++ L++ + G V +P SV + N+
Sbjct: 229 SRPERDRTPGDVVDTEDPVVVRIAREHGVHPALVCLKWAVARGQVPIPFSVKPAQYTANL 288
Query: 152 Q 150
+
Sbjct: 289 R 289
>UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3;
Magnoliophyta|Rep: Putative uncharacterized protein -
Vitis vinifera (Grape)
Length = 304
Score = 41.5 bits (93), Expect = 0.011
Identities = 28/107 (26%), Positives = 50/107 (46%)
Frame = -2
Query: 440 PXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXPSKAQPDAPPPRIDDERLVSIA 261
P +Q+E + Q +L + + + P GS + + D + L A
Sbjct: 157 PAVIQVECHPSWQQSKLHAFCKSKGVHLTGFSPLGSPGTTWFKGDI----LKHPVLTMAA 212
Query: 260 QKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLXXFSXTPEE 120
+K K+ Q ALR+ +++G VLPKS + R ++N + +S PE+
Sbjct: 213 EKLGKSPAQVALRWGLQMGHSVLPKSTSESRIKENFDVFGWS-XPED 258
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 41.1 bits (92), Expect = 0.014
Identities = 37/141 (26%), Positives = 62/141 (43%), Gaps = 4/141 (2%)
Frame = -2
Query: 506 SIGISNFXQXQ----IQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPF 339
SIGISNF + I+ I L P QIE + + + + + A+ P
Sbjct: 134 SIGISNFYPAKFVEFIKVIKTMNLPVPQIDQIEFHPYYQEKVARQLHDKYGVQIEAWGPL 193
Query: 338 GSLXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQ 159
G +K P LV IA K++K+V Q LR++++ + + KSV+ R +
Sbjct: 194 GRTA-NKYDTFHQP------ELVEIAAKHDKSVGQVVLRWIMQSNIITVAKSVNPSRMAE 246
Query: 158 NIQLXXFSXTPEEXNLXKSFD 96
NI + F ++ ++ D
Sbjct: 247 NIDIFNFELDDDDMKKIETLD 267
>UniRef50_A7RPK2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 151
Score = 41.1 bits (92), Expect = 0.014
Identities = 33/137 (24%), Positives = 56/137 (40%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SNF ++++ D P A+Q + +EN+I M Y G +
Sbjct: 17 SIGVSNFEVKDLKKLKDIAKVPPSAIQNFFTPFYQDKATRQYCKENNIKYMGYSTLGGMY 76
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
+ D P + + E L I ++ TV Q L++ +E +V+P+S N L
Sbjct: 77 VREGF-DKNPVQNNFE-LQRIGGVFDATVSQVVLKWALEQDVLVIPQSRTPNHIRTNFHL 134
Query: 146 XXFSXTPEEXNLXKSFD 96
++ S D
Sbjct: 135 DHVQLDSKQMAYFDSLD 151
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 41.1 bits (92), Expect = 0.014
Identities = 30/117 (25%), Positives = 51/117 (43%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SN + ++R++D P Q E + Q + + ++ I+ A+ P GS
Sbjct: 160 SIGVSNVSEVYLKRLLDQVKTVPAVNQFEIHPYLPQKKEIEFNEKHGILVTAFSPLGSST 219
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
+ + P V IAQK+N + + + + VLPK+ ER N
Sbjct: 220 GALKLHENP-------IAVEIAQKHNTSTGSVLINWHVSQKRAVLPKTRSIERVVAN 269
>UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2;
Filobasidiella neoformans|Rep: Putative uncharacterized
protein - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 334
Score = 41.1 bits (92), Expect = 0.014
Identities = 46/157 (29%), Positives = 72/157 (45%), Gaps = 22/157 (14%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKP----XALQIEXNLXXXQPE---LFKXXRENDIVXMAY 348
+IG+SNF + ++ ++ D LEK + QIE +L PE L + ++ I +AY
Sbjct: 165 AIGVSNFSKDELIKMSDL-LEKHGVKIASNQIEFSLLRQLPEENRLLEEMKKRGIACLAY 223
Query: 347 XPF--GSLXP--SKAQPDAPPPRIDD-------ERLVS----IAQKYNKTVPQXALRFLI 213
P G L + + P P R E L+S +A KY T AL +++
Sbjct: 224 SPLAMGRLTGKYNASNPIPPGRRFSSQYSWEQLEPLISELGTLANKYEVTHSAVALNWVM 283
Query: 212 ELGAVVLPKSVHKERXEQNIQLXXFSXTPEEXNLXKS 102
GA+ L + +K + EQN + F T EE + S
Sbjct: 284 CKGAIPLGGARNKSQAEQNAKAVTFKLTDEEVDRLSS 320
>UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces
capsulatus NAm1|Rep: Predicted protein - Ajellomyces
capsulatus NAm1
Length = 315
Score = 41.1 bits (92), Expect = 0.014
Identities = 31/129 (24%), Positives = 56/129 (43%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
S+G+ + Q + ++ KP QIE + +L + I +++ P G
Sbjct: 115 SLGVCSLSQKSMDVLLKECTVKPVINQIEVHPFNPSLKLVPYCLDKGIQVISWGPLGG-G 173
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P D + + L S+A +YN ++ + +L++ G V +P S + R + N L
Sbjct: 174 PKSLYFDT-SSMYNHKTLTSLASRYNVSIELIMISWLVQRGIVPIPHSASRARMDDN--L 230
Query: 146 XXFSXTPEE 120
S T EE
Sbjct: 231 SPVSLTDEE 239
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 40.7 bits (91), Expect = 0.019
Identities = 33/138 (23%), Positives = 58/138 (42%), Gaps = 4/138 (2%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPE---LFKXXRENDIVXMAYXPFGS 333
IG+SNF + ++ I E Q++ N+ PE L + ++N + +AY P
Sbjct: 144 IGVSNFDRRLLEEAISKSQEPIVCDQVKYNIEDRDPERDGLLEFCQKNGVTLVAYSPLRR 203
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLI-ELGAVVLPKSVHKERXEQN 156
S+ L IA+ + T+ Q L +L+ + V +PK+ E +N
Sbjct: 204 TLLSEK---------TKRTLEEIAKNHGATIYQIMLAWLLAKPNVVAIPKAGRVEHLREN 254
Query: 155 IQLXXFSXTPEEXNLXKS 102
++ + EE L S
Sbjct: 255 LKATEIKLSEEEMKLLDS 272
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 40.7 bits (91), Expect = 0.019
Identities = 33/123 (26%), Positives = 53/123 (43%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXP 324
IG+SN Q++ I Q+E + Q L R++ + AY +G
Sbjct: 132 IGVSNQNIAQMRESIARSAAPIVTNQVELHPYLPQHSLVAAARDSAVAVTAY--YG---- 185
Query: 323 SKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLX 144
D P+ D L I +Y K+ Q LR+L++ G V L K+ + R +NI +
Sbjct: 186 ---MADGAVPK--DPVLQQIGARYGKSAAQVGLRWLVQQGYVALSKTANPARVAENIAIF 240
Query: 143 XFS 135
F+
Sbjct: 241 DFA 243
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 40.7 bits (91), Expect = 0.019
Identities = 34/130 (26%), Positives = 54/130 (41%), Gaps = 1/130 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELF-KXXRENDIVXMAYXPFGSL 330
SIG+SNF + ++ I+++ P Q+E + + F RE I ++ +
Sbjct: 143 SIGVSNFQRNHLEAILETCSVVPAINQLEYHPYLQRSHDFIPWMRERGIEVSSFKTLAPV 202
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
K P DE L SIA K+N T L ++I V + + +ER E+ I
Sbjct: 203 TVGKGGPL-------DEPLASIAAKHNITTSAVVLNWVISQNIVPITTTTKRERMEEYIA 255
Query: 149 LXXFSXTPEE 120
EE
Sbjct: 256 AISLQLDREE 265
>UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative;
n=1; Aspergillus fumigatus|Rep: Glycerol dehydrogenase
(GCY1), putative - Aspergillus fumigatus (Sartorya
fumigata)
Length = 274
Score = 40.3 bits (90), Expect = 0.024
Identities = 32/132 (24%), Positives = 58/132 (43%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG++N+ ++ + P Q+E + Q L + ++ I+ AY P GS
Sbjct: 124 AIGVANWSIPYLEELKKKWTVVPAVNQVELHPFLPQHALKEWCDKHGILLEAYSPLGS-- 181
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
P + D + +A+KY + + + + G VVLPKS + R N Q+
Sbjct: 182 -------EGAPLMSDPAIQEMAKKYGVSPATVLISYHVNRGVVVLPKSTQENRILSNRQV 234
Query: 146 XXFSXTPEEXNL 111
S PE+ ++
Sbjct: 235 IPLS--PEDMDV 244
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 39.9 bits (89), Expect = 0.032
Identities = 31/131 (23%), Positives = 60/131 (45%), Gaps = 2/131 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXN--LXXXQPELFKXXRENDIVXMAYXPFGS 333
+IG+SN +++ II KP QIE + L P + +++DIV Y P S
Sbjct: 144 AIGVSNHSPAELETIIKVAKIKPHVNQIEFHPLLQEPTPGIVDFCKQHDIVVEGYSPLAS 203
Query: 332 LXPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
++ + + P D + ++A+ +N + LR+ + G V + S + R ++ +
Sbjct: 204 ---NELEGEKPL----DAVVANVAKNHNVSPGSVLLRWATQKGIVPITTSANAGRQKEAL 256
Query: 152 QLXXFSXTPEE 120
+ F + E
Sbjct: 257 AIFDFKLSDGE 267
>UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella
pneumophila|Rep: D-xylose reductase III - Legionella
pneumophila subsp. pneumophila (strain Philadelphia 1
/ATCC 33152 / DSM 7513)
Length = 280
Score = 39.5 bits (88), Expect = 0.043
Identities = 30/129 (23%), Positives = 58/129 (44%), Gaps = 1/129 (0%)
Frame = -2
Query: 503 IGISNFXQXQIQRIIDSGLEKPXALQIE-XNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+GISN Q++ + KP +Q + ++ ++N I+ Y F L
Sbjct: 153 LGISNVNMVQVEELYRKVSIKPSFIQNRCFAITQWDQDVRTFSQKNKII---YQGFSLLT 209
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
++ P + S+A KY+KT+PQ RF ++G + L + +++ + ++ +
Sbjct: 210 ANQRYLLNP-------HMQSLAVKYDKTIPQIIFRFANQVGILPLTGTTNQQHMDNDLNI 262
Query: 146 XXFSXTPEE 120
F T EE
Sbjct: 263 YDFELTQEE 271
>UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona
intestinalis|Rep: Aldo-keto reductase 1a - Ciona
intestinalis (Transparent sea squirt)
Length = 584
Score = 39.5 bits (88), Expect = 0.043
Identities = 30/139 (21%), Positives = 56/139 (40%), Gaps = 2/139 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SN +Q ++ A+Q + + E+ +N+I M Y G
Sbjct: 412 SIGVSNIYIEDLQYLVKMAKTPISAVQNWFDPLHQEREIRALCAKNNIRFMGYSALGFTW 471
Query: 326 PSKAQPDAPP--PRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI 153
K Q P + ++ +V+I ++ LR+ +E+ V+P + + + EQN+
Sbjct: 472 IDKEQGLGRDVNPVLTNQNIVAIGNNHDLPTTLVVLRWAMEMNVTVMPCTTNVDHLEQNL 531
Query: 152 QLXXFSXTPEEXNLXKSFD 96
F + L D
Sbjct: 532 NSRLFPLDNKSFPLIDQLD 550
>UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 301
Score = 39.5 bits (88), Expect = 0.043
Identities = 37/146 (25%), Positives = 58/146 (39%), Gaps = 1/146 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
SIG+SN+ + + + +P Q E +P L K N+IV +Y
Sbjct: 158 SIGVSNYEVYHLVEMFEYAKIRPVLNQYEYQPYLTRPTLKKFCDLNNIVVQSYS------ 211
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNI-Q 150
S D + ++ LV + QKYN+T F ++PKS R N+
Sbjct: 212 -SLCWGD--KEILQEKPLVDLCQKYNQTPQAILYAFAHCSNTSMIPKSATPSRIHDNLHN 268
Query: 149 LXXFSXTPEEXNLXKSFDTGXRTLPQ 72
T +E +S D G ++ PQ
Sbjct: 269 TIKIKLTEDELKSLRSLDKG-KSFPQ 293
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 39.5 bits (88), Expect = 0.043
Identities = 34/142 (23%), Positives = 60/142 (42%), Gaps = 1/142 (0%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKP-XALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
++G+SNF ++ +D L+ P A Q+E + Q EL + E D +AY P
Sbjct: 138 NVGVSNFEPHHVETAMDV-LDAPVFANQVETHPFLQQSELREHAAEQDYELVAYSPL--- 193
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQ 150
A + + +IA ++ + Q +L +L E G +PK+ + N+
Sbjct: 194 --------ARGEVFGHDVIEAIADDHDASEAQVSLAWLREKGVTAIPKATSEAHITDNLA 245
Query: 149 LXXFSXTPEEXNLXKSFDTGXR 84
S T + + + DT R
Sbjct: 246 SLDLSLTDADIDRIDNIDTVDR 267
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 39.1 bits (87), Expect = 0.057
Identities = 30/119 (25%), Positives = 56/119 (47%), Gaps = 2/119 (1%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXAL-QIEXNLXXXQPELFKXXRENDIVXMAYXPFGSL 330
+IG++NF +++ ++ ++ P A Q+E ++ Q +L + I +AY P L
Sbjct: 131 AIGVANFTVALLKQAVED-IQAPVACNQVEYHVMLDQSKLMAYMKSRSIPLVAYCP---L 186
Query: 329 XPSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIEL-GAVVLPKSVHKERXEQN 156
+A DE L I +K+ Q AL++L++ G +PK+ E + N
Sbjct: 187 AQGRA--------AGDETLAGIGRKHGAGAAQVALKWLLDQDGVAAIPKAARPESQQAN 237
>UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose
reductase (AR) (Aldehyde reductase); n=1; Canis lupus
familiaris|Rep: PREDICTED: similar to Aldose reductase
(AR) (Aldehyde reductase) - Canis familiaris
Length = 182
Score = 38.7 bits (86), Expect = 0.075
Identities = 21/81 (25%), Positives = 39/81 (48%)
Frame = -2
Query: 281 ERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLXXFSXTPEEXNLXKS 102
E+ A K+NKT Q ++F ++ V++PKS+ E +N Q+ F + + +
Sbjct: 103 EKTCHCAAKHNKTTAQVLIQFPMQGNLVMIPKSMTPEHIAENFQVFDFELSSMDMTTLLN 162
Query: 101 FDTGXRTLPQTKWSKHPDXPF 39
++ R ++ H D PF
Sbjct: 163 YNGNWRV-----YASHKDYPF 178
>UniRef50_Q14LU7 Cluster: Putative aldo/keto reductase n-terminal
and c-terminal truncated oxidoreductase protein; n=1;
Spiroplasma citri|Rep: Putative aldo/keto reductase
n-terminal and c-terminal truncated oxidoreductase
protein - Spiroplasma citri
Length = 90
Score = 38.7 bits (86), Expect = 0.075
Identities = 25/92 (27%), Positives = 46/92 (50%)
Frame = -2
Query: 443 KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXPSKAQPDAPPPRIDDERLVSI 264
KP Q+E + ++ K +EN+I+ ++ +L + ++ ++ I
Sbjct: 7 KPMVNQVELHPGLNNTDVIKFCQENNIIIESWA---TLMQGQCMTNST--------VLKI 55
Query: 263 AQKYNKTVPQXALRFLIELGAVVLPKSVHKER 168
A+K+ K Q L++ I+ VV+PKS HKER
Sbjct: 56 AEKHQKNPAQICLKWAIQQNIVVIPKSTHKER 87
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 38.3 bits (85), Expect = 0.099
Identities = 26/91 (28%), Positives = 42/91 (46%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SNF +++ ++ P A Q+E + Q +L + +E I AY P G
Sbjct: 160 AIGVSNFSCKKLETLLSFATISPAANQVEVHPYCRQNKLREFCKEKGIQLCAYSPLG--- 216
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQ 234
K P + +D L IA + KT+ Q
Sbjct: 217 -GKGTPWSNNAVMDCPLLKQIAMERGKTIAQ 246
>UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n=1;
Ajellomyces capsulatus NAm1|Rep: NAD(P)H-dependent
D-xylose reductase - Ajellomyces capsulatus NAm1
Length = 289
Score = 38.3 bits (85), Expect = 0.099
Identities = 28/111 (25%), Positives = 46/111 (41%), Gaps = 3/111 (2%)
Frame = -2
Query: 443 KPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLXPSKAQPDA---PPPRIDDERL 273
K LQIE + Q L REN I AY F + K P + +
Sbjct: 149 KSATLQIEHHSYLTQCLLVNFARENGIAVTAYSSFTNTSFLKLNMQIARNARPLLSHPVI 208
Query: 272 VSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQLXXFSXTPEE 120
+++ +++T Q LR+ + G V+ KS + R +N+++ F E
Sbjct: 209 TPVSRMHDRTSAQVVLRWATQQGIAVILKSNSETRLLENLRVNDFGLEQNE 259
>UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=2;
Ostreococcus|Rep: Aldo/keto reductase family proteins -
Ostreococcus tauri
Length = 336
Score = 37.5 bits (83), Expect = 0.17
Identities = 29/117 (24%), Positives = 49/117 (41%)
Frame = -2
Query: 506 SIGISNFXQXQIQRIIDSGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
+IG+SN+ ++ ++ KP QIE + Q EL + + Y P G
Sbjct: 193 AIGVSNYELSHLRELLQFCDVKPAVNQIELHARFPQTELRAFCESVGVHVVGYSPLGV-- 250
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQN 156
+DD+R+ + A +R+ + +GA V+ KS ER E+N
Sbjct: 251 ---------GALLDDDRVKAYAATIGLRPAPALVRWTLSMGASVVVKSSAAERTEEN 298
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 36.7 bits (81), Expect = 0.30
Identities = 34/129 (26%), Positives = 51/129 (39%), Gaps = 1/129 (0%)
Frame = -2
Query: 503 IGISNFXQXQIQRIID-SGLEKPXALQIEXNLXXXQPELFKXXRENDIVXMAYXPFGSLX 327
IG+SNF Q Q+ + G + QIE + EL + N+I AY P G
Sbjct: 134 IGVSNFTQSQLDEALSILGKDHILTNQIEVHPNFQNKELVAYCQRNNIQVTAYMPLG--- 190
Query: 326 PSKAQPDAPPPRIDDERLVSIAQKYNKTVPQXALRFLIELGAVVLPKSVHKERXEQNIQL 147
K ++++ L IA ++ T AL +L V +P S + N+
Sbjct: 191 VGKV--------MENDILNDIASAHDTTPSAVALAWLSHKKIVAIPSSTNVNHMRDNLTA 242
Query: 146 XXFSXTPEE 120
T EE
Sbjct: 243 KQMMLTAEE 251
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 400,429,868
Number of Sequences: 1657284
Number of extensions: 5842499
Number of successful extensions: 14731
Number of sequences better than 10.0: 268
Number of HSP's better than 10.0 without gapping: 14258
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 14542
length of database: 575,637,011
effective HSP length: 95
effective length of database: 418,195,031
effective search space used: 30528237263
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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