Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner12a11f
(634 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase precu... 181 1e-44
UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA... 172 7e-42
UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1; Tri... 170 2e-41
UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto ... 168 1e-40
UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13... 152 6e-36
UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep: GA1... 152 8e-36
UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5; Bacteroidetes|... 150 3e-35
UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium ... 148 1e-34
UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9; Endopterygota|... 146 3e-34
UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p... 146 5e-34
UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA ... 145 7e-34
UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13; Pezizomycotin... 143 3e-33
UniRef50_Q41399 Cluster: Chalcone reductase; n=4; eudicotyledons... 139 4e-32
UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep... 139 6e-32
UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;... 138 8e-32
UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18... 138 1e-31
UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep... 137 2e-31
UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3; ... 136 4e-31
UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Re... 135 7e-31
UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep: R... 135 1e-30
UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1; Or... 135 1e-30
UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gamb... 134 1e-30
UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44; Bi... 134 1e-30
UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase; n... 134 2e-30
UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1 ... 101 2e-30
UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4; ... 133 4e-30
UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=... 133 4e-30
UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:... 132 7e-30
UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila melanogaste... 132 7e-30
UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone synt... 132 7e-30
UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;... 132 9e-30
UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30; Tetrapoda|... 132 9e-30
UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep: ... 131 1e-29
UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA... 131 2e-29
UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|R... 131 2e-29
UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus tropica... 130 3e-29
UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep: ... 130 3e-29
UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon ... 129 5e-29
UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6; ... 129 6e-29
UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+... 128 8e-29
UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase fam... 128 1e-28
UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-l... 95 1e-28
UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate r... 127 2e-28
UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1; ... 127 3e-28
UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28; Magnolio... 127 3e-28
UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep: A... 126 4e-28
UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4; Catarrhini... 95 4e-28
UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes aegypti... 126 6e-28
UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 125 8e-28
UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreducta... 125 1e-27
UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella ve... 124 1e-27
UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1; ... 124 2e-27
UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 124 2e-27
UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium... 124 2e-27
UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;... 123 3e-27
UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep: ... 122 7e-27
UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2; Chroococcal... 122 7e-27
UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Re... 122 7e-27
UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2; ... 121 1e-26
UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of str... 121 2e-26
UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+... 121 2e-26
UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:... 120 3e-26
UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1; Prop... 120 3e-26
UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 120 4e-26
UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3; ... 119 5e-26
UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reduct... 119 7e-26
UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate divi... 119 7e-26
UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14; Di... 119 7e-26
UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreducta... 119 7e-26
UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase fam... 118 1e-25
UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Ald... 118 1e-25
UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2; ... 118 2e-25
UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (E... 118 2e-25
UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein; ... 117 2e-25
UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lambl... 117 3e-25
UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase fam... 117 3e-25
UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2; ... 117 3e-25
UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Re... 116 5e-25
UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=... 116 6e-25
UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32; Magnoliophyt... 116 6e-25
UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1; ... 116 6e-25
UniRef50_P22045 Cluster: Probable reductase; n=101; cellular org... 115 1e-24
UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 115 1e-24
UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto ... 114 1e-24
UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;... 114 1e-24
UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate r... 114 2e-24
UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep: CG27... 114 2e-24
UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1; E... 113 3e-24
UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2; Actinomyc... 113 3e-24
UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 113 3e-24
UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; cor... 113 3e-24
UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452 ... 113 4e-24
UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate d... 113 4e-24
UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=... 112 6e-24
UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10... 112 8e-24
UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|R... 112 8e-24
UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core eudicotyled... 111 1e-23
UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 111 1e-23
UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 - ... 111 2e-23
UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep: Zgc:... 110 2e-23
UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Re... 110 2e-23
UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase fam... 110 2e-23
UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose red... 110 3e-23
UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 110 3e-23
UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;... 109 5e-23
UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 109 5e-23
UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3; ... 109 5e-23
UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9; Endopterygota... 108 9e-23
UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC 7... 107 2e-22
UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate r... 107 2e-22
UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8; Saccharomy... 107 2e-22
UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1; ... 107 2e-22
UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 107 2e-22
UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium SCB... 107 3e-22
UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole geno... 107 3e-22
UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of str... 107 3e-22
UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase fam... 106 4e-22
UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1; Lactobaci... 106 4e-22
UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus djamor|... 106 4e-22
UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1; ... 106 4e-22
UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4; Rhodobacterac... 106 5e-22
UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1; Corynebac... 105 1e-21
UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several... 105 1e-21
UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase... 104 2e-21
UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep: ... 104 2e-21
UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 104 2e-21
UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5; Sacchar... 104 2e-21
UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4... 103 4e-21
UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7... 103 4e-21
UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3; ... 103 4e-21
UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gamb... 103 5e-21
UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4; Actinomycetal... 102 6e-21
UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8; S... 102 8e-21
UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reduct... 101 1e-20
UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase fam... 101 1e-20
UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase fam... 101 1e-20
UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep... 101 1e-20
UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6; ... 101 2e-20
UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reduct... 101 2e-20
UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus coag... 101 2e-20
UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reduct... 100 3e-20
UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep: ... 100 3e-20
UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Re... 100 3e-20
UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-l... 100 3e-20
UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep: Zgc:1... 99 4e-20
UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2; Corynebac... 100 6e-20
UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reducta... 100 6e-20
UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=... 100 6e-20
UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3... 100 6e-20
UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;... 99 8e-20
UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1; ... 99 1e-19
UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep: ... 99 1e-19
UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto ... 98 1e-19
UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:... 98 1e-19
UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate r... 98 1e-19
UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 98 2e-19
UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1; Fil... 98 2e-19
UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus ter... 98 2e-19
UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter... 97 2e-19
UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9; ... 97 2e-19
UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1; Phy... 97 2e-19
UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus n... 97 2e-19
UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genom... 97 4e-19
UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella ve... 96 5e-19
UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid red... 95 9e-19
UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3; ... 95 1e-18
UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:... 95 2e-18
UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep: Li... 94 2e-18
UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep: O... 94 3e-18
UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase fam... 94 3e-18
UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 94 3e-18
UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2; ... 94 3e-18
UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1; ... 94 3e-18
UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1; Gri... 91 4e-18
UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;... 93 4e-18
UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of str... 93 4e-18
UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1; ... 93 4e-18
UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto ... 93 5e-18
UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;... 93 5e-18
UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep: Li... 93 5e-18
UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase fam... 93 7e-18
UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep: Lm... 93 7e-18
UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase fam... 93 7e-18
UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lambl... 93 7e-18
UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldeh... 93 7e-18
UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] hea... 93 7e-18
UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=... 92 1e-17
UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5; Bacteria... 92 1e-17
UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate r... 91 2e-17
UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 91 2e-17
UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales ba... 91 2e-17
UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep... 91 2e-17
UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2; Gammaproteoba... 91 2e-17
UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1; ... 91 2e-17
UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2; Micrococcinea... 91 2e-17
UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reduct... 91 3e-17
UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101... 91 3e-17
UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase fami... 91 3e-17
UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1; ... 91 3e-17
UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep: Li... 90 4e-17
UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 - Mycop... 90 4e-17
UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8; Gammaproteoba... 90 4e-17
UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1; Act... 90 5e-17
UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1; ... 90 5e-17
UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5; ... 89 6e-17
UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n... 89 1e-16
UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=... 89 1e-16
UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium... 88 1e-16
UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;... 88 2e-16
UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 88 2e-16
UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Re... 88 2e-16
UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase fam... 87 3e-16
UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1; ... 87 3e-16
UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1; ... 87 3e-16
UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1; ... 87 4e-16
UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 86 6e-16
UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7; Saccharomycet... 86 6e-16
UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase fami... 86 6e-16
UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1; ... 86 8e-16
UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella ve... 85 1e-15
UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep: ... 85 1e-15
UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium... 85 1e-15
UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1; ... 85 2e-15
UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep... 85 2e-15
UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase fam... 84 2e-15
UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2; ... 84 2e-15
UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes aegypti... 84 2e-15
UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein; ... 84 2e-15
UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Re... 84 3e-15
UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1; ... 83 4e-15
UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase oxidoreduc... 83 5e-15
UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4; ... 83 5e-15
UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 83 7e-15
UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep... 82 1e-14
UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide reduct... 82 1e-14
UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1... 81 2e-14
UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22; Pez... 81 2e-14
UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2; Halobacteri... 81 2e-14
UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate r... 80 4e-14
UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 80 4e-14
UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis v... 80 5e-14
UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6; Halobacteriace... 80 5e-14
UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=1... 79 7e-14
UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4; ... 79 7e-14
UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2; ... 79 7e-14
UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep... 79 9e-14
UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella ve... 79 1e-13
UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1; ... 79 1e-13
UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1; Sc... 79 1e-13
UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10; Alphaproteob... 78 2e-13
UniRef50_A2QB88 Cluster: Contig An01c0460, complete genome. prec... 78 2e-13
UniRef50_Q7VHE1 Cluster: Putative uncharacterized protein; n=1; ... 77 3e-13
UniRef50_Q5NLW3 Cluster: Putative oxidoreductase; n=1; Zymomonas... 77 4e-13
UniRef50_Q14LU6 Cluster: Putative aldo/keto reductase oxidoreduc... 77 4e-13
UniRef50_Q5KCN9 Cluster: Putative uncharacterized protein; n=1; ... 77 5e-13
UniRef50_Q5B5R6 Cluster: Putative uncharacterized protein; n=1; ... 77 5e-13
UniRef50_UPI0000D56CE5 Cluster: PREDICTED: similar to CG6084-PA,... 76 6e-13
UniRef50_A6RMS0 Cluster: Putative uncharacterized protein; n=1; ... 76 6e-13
UniRef50_Q1DLF1 Cluster: Putative uncharacterized protein; n=1; ... 76 8e-13
UniRef50_Q9V2P1 Cluster: Myo-inositol degradation; n=5; Archaea|... 76 8e-13
UniRef50_Q4JCC1 Cluster: 2,5-diketo-D-gluconic acid reductase A;... 76 8e-13
UniRef50_Q4WUF7 Cluster: Aldo-keto reductase, putative; n=3; Pez... 75 1e-12
UniRef50_Q5V398 Cluster: Oxidoreductase aldo/keto reductase fami... 75 1e-12
UniRef50_Q00XM4 Cluster: Aldo/keto reductase family proteins; n=... 75 2e-12
UniRef50_Q5UYI9 Cluster: Oxidoreductase; n=1; Haloarcula marismo... 75 2e-12
UniRef50_Q16CS5 Cluster: 2,5-diketo-D-gluconic acid reductase B,... 74 2e-12
UniRef50_Q68A33 Cluster: Aldo-keto reductase 1a; n=1; Ciona inte... 74 3e-12
UniRef50_Q5KKZ8 Cluster: Aldo-keto reductase, putative; n=2; Fil... 74 3e-12
UniRef50_Q97U17 Cluster: Oxidoreductase, aldo/keto reductase fam... 74 3e-12
UniRef50_A3WP89 Cluster: Aldo/keto reductase; n=1; Idiomarina ba... 73 6e-12
UniRef50_A3T261 Cluster: Putative uncharacterized protein; n=1; ... 73 6e-12
UniRef50_Q9P734 Cluster: Related to 2, 5-diketo-D-gluconic acid ... 73 8e-12
UniRef50_Q5KD52 Cluster: Oxidoreductase, putative; n=1; Filobasi... 73 8e-12
UniRef50_Q59ZT1 Cluster: Putative uncharacterized protein; n=1; ... 73 8e-12
UniRef50_A7D7K7 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 73 8e-12
UniRef50_A1CAM7 Cluster: Aldo-keto reductase, putative; n=9; Dik... 72 1e-11
UniRef50_Q5V1M9 Cluster: Oxidoreductase aldo/keto reductase fami... 72 1e-11
UniRef50_Q21274 Cluster: Putative uncharacterized protein; n=1; ... 71 2e-11
UniRef50_A4IJ00 Cluster: LOC548351 protein; n=1; Xenopus tropica... 67 3e-11
UniRef50_A5BF24 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_Q17568 Cluster: Putative uncharacterized protein; n=1; ... 70 4e-11
UniRef50_Q4WP69 Cluster: Aldehyde reductase, putative; n=1; Aspe... 70 4e-11
UniRef50_A7D6I8 Cluster: Aldo/keto reductase; n=1; Halorubrum la... 70 4e-11
UniRef50_Q8EVS8 Cluster: Oxidoreductase; n=1; Mycoplasma penetra... 70 5e-11
UniRef50_Q4DJ59 Cluster: Aldo/keto reductase, putative; n=2; Try... 70 5e-11
UniRef50_Q59Z55 Cluster: Potential aldo/keto reductase; n=6; Sac... 70 5e-11
UniRef50_A2G4I3 Cluster: Oxidoreductase, aldo/keto reductase fam... 69 7e-11
UniRef50_A6SI80 Cluster: Putative uncharacterized protein; n=1; ... 69 7e-11
UniRef50_Q6L139 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 69 7e-11
UniRef50_Q9C1X5 Cluster: Xylose and arabinose reductase; n=1; Sc... 69 1e-10
UniRef50_Q5KKC5 Cluster: Putative uncharacterized protein; n=2; ... 68 2e-10
UniRef50_A0LJ47 Cluster: Aldo/keto reductase; n=1; Syntrophobact... 68 2e-10
UniRef50_Q6WGK4 Cluster: Aldose reductase; n=1; Pristionchus pac... 68 2e-10
UniRef50_Q6CWB9 Cluster: Similarities with sp|Q12458 Saccharomyc... 68 2e-10
UniRef50_Q97UV9 Cluster: Oxidoreductase; n=1; Sulfolobus solfata... 68 2e-10
UniRef50_A7D761 Cluster: Aldo/keto reductase; n=2; Halobacteriac... 68 2e-10
UniRef50_Q8EVT8 Cluster: Oxidoreductase-aldo/keto reductase fami... 67 4e-10
UniRef50_Q5KPU6 Cluster: Putative uncharacterized protein; n=2; ... 67 4e-10
UniRef50_A3DNU7 Cluster: Aldo/keto reductase; n=3; Desulfurococc... 66 5e-10
UniRef50_A1CHK2 Cluster: Aldose 1-epimerase, putative; n=11; Pez... 66 7e-10
UniRef50_Q1IQ78 Cluster: Aldo/keto reductase; n=1; Acidobacteria... 66 9e-10
UniRef50_Q013C5 Cluster: Glycerol dehydrogenase, putative; n=2; ... 66 9e-10
UniRef50_Q8EUX1 Cluster: Aldo/keto reductase family oxidoreducta... 65 1e-09
UniRef50_Q1EZH4 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 65 1e-09
UniRef50_Q9USV2 Cluster: Xylose and arabinose reductase; n=2; Sc... 65 1e-09
UniRef50_A5AD50 Cluster: Putative uncharacterized protein; n=3; ... 65 2e-09
UniRef50_Q4PE96 Cluster: Putative uncharacterized protein; n=1; ... 64 2e-09
UniRef50_P80874 Cluster: General stress protein 69; n=16; cellul... 64 2e-09
UniRef50_UPI000038E317 Cluster: hypothetical protein Faci_030017... 64 4e-09
UniRef50_Q89RG2 Cluster: Aldo/keto reductase; n=11; Bacteria|Rep... 64 4e-09
UniRef50_Q5B034 Cluster: Putative uncharacterized protein; n=1; ... 63 5e-09
UniRef50_P76234 Cluster: Uncharacterized protein yeaE; n=39; Bac... 62 1e-08
UniRef50_Q5FHT2 Cluster: Aldehyde reductase; n=4; Lactobacillus|... 62 1e-08
UniRef50_Q18903 Cluster: Putative uncharacterized protein C56G3.... 61 2e-08
UniRef50_A6QVW8 Cluster: Predicted protein; n=1; Ajellomyces cap... 61 2e-08
UniRef50_Q4Q973 Cluster: Aldo/keto reductase, putative; n=3; Lei... 60 3e-08
UniRef50_Q4Q5X1 Cluster: Aldehyde reductase, putative; n=75; cel... 60 3e-08
UniRef50_Q7M4N1 Cluster: Dihydrodiol dehydrogenase DD2; n=2; Hom... 60 3e-08
UniRef50_Q97V56 Cluster: Dehydrogenase; n=8; Thermoprotei|Rep: D... 60 3e-08
UniRef50_Q391C9 Cluster: Aldo/keto reductase; n=10; Proteobacter... 60 4e-08
UniRef50_UPI000023DF27 Cluster: hypothetical protein FG07276.1; ... 60 6e-08
UniRef50_A7EW94 Cluster: Putative uncharacterized protein; n=1; ... 60 6e-08
UniRef50_Q8ZU65 Cluster: Aldo-keto reductase, putative; n=4; The... 60 6e-08
UniRef50_A4M6J9 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 59 8e-08
UniRef50_A3H9Y8 Cluster: Aldo/keto reductase; n=2; Caldivirga ma... 59 8e-08
UniRef50_A2UBC7 Cluster: Aldo/keto reductase; n=3; cellular orga... 59 1e-07
UniRef50_A4R217 Cluster: Putative uncharacterized protein; n=1; ... 59 1e-07
UniRef50_Q0GU15 Cluster: ORF28; n=3; Bacteria|Rep: ORF28 - Lacto... 58 1e-07
UniRef50_UPI00015BB020 Cluster: aldo/keto reductase; n=1; Ignico... 58 2e-07
UniRef50_Q5ZTU6 Cluster: D-xylose reductase III; n=5; Legionella... 58 2e-07
UniRef50_A6QXT4 Cluster: Predicted protein; n=1; Ajellomyces cap... 58 2e-07
UniRef50_Q6NKP1 Cluster: At5g53580; n=18; cellular organisms|Rep... 58 2e-07
UniRef50_Q8YXI8 Cluster: All1225 protein; n=9; Cyanobacteria|Rep... 57 4e-07
UniRef50_Q7NK63 Cluster: Gll1617 protein; n=1; Gloeobacter viola... 57 4e-07
UniRef50_Q64W37 Cluster: 2,5-diketo-D-gluconic acid reductase; n... 57 4e-07
UniRef50_Q64UK5 Cluster: Aldo/keto reductase family oxidoreducta... 56 5e-07
UniRef50_A6BIJ0 Cluster: Putative uncharacterized protein; n=1; ... 56 5e-07
UniRef50_Q55FL2 Cluster: Putative uncharacterized protein; n=1; ... 55 2e-06
UniRef50_A1S0T5 Cluster: Aldo/keto reductase; n=2; Thermoprotei|... 55 2e-06
UniRef50_P82125 Cluster: 1,5-anhydro-D-fructose reductase; n=1; ... 55 2e-06
UniRef50_Q04TM6 Cluster: Aryl-alcohol dehydrogenase-related oxid... 54 2e-06
UniRef50_A7LSN6 Cluster: Putative uncharacterized protein; n=3; ... 54 2e-06
UniRef50_A7BLU0 Cluster: Aldo/keto reductase family; n=1; Beggia... 54 2e-06
UniRef50_P91021 Cluster: Putative uncharacterized protein; n=1; ... 54 2e-06
UniRef50_Q94A68 Cluster: Uncharacterized oxidoreductase At1g0669... 54 2e-06
UniRef50_Q55493 Cluster: Auxin-induced protein; n=2; Bacteria|Re... 54 3e-06
UniRef50_Q3ZWR6 Cluster: Oxidoreductase, aldo reductase; n=3; De... 54 3e-06
UniRef50_Q21EY6 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 54 4e-06
UniRef50_A5V463 Cluster: Aldo/keto reductase; n=1; Sphingomonas ... 54 4e-06
UniRef50_A1SLH1 Cluster: Aldo/keto reductase; n=27; Bacteria|Rep... 54 4e-06
UniRef50_Q61U89 Cluster: Putative uncharacterized protein CBG054... 53 5e-06
UniRef50_Q55ML8 Cluster: Putative uncharacterized protein; n=2; ... 53 5e-06
UniRef50_Q2NGB6 Cluster: Predicted oxidoreductase; n=1; Methanos... 53 5e-06
UniRef50_Q46851 Cluster: Uncharacterized protein yghZ; n=126; Ba... 53 5e-06
UniRef50_UPI00005A2CCB Cluster: PREDICTED: similar to Aldose red... 53 7e-06
UniRef50_A6X3I0 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 53 7e-06
UniRef50_Q9W2X0 Cluster: CG32688-PA, isoform A; n=4; Sophophora|... 53 7e-06
UniRef50_A7RXR1 Cluster: Predicted protein; n=3; Eumetazoa|Rep: ... 53 7e-06
UniRef50_Q97UJ7 Cluster: Oxidoreductase; n=4; Archaea|Rep: Oxido... 53 7e-06
UniRef50_A7AFQ7 Cluster: Putative uncharacterized protein; n=1; ... 52 9e-06
UniRef50_A5CYR4 Cluster: Predicted oxidoreductases; n=2; Clostri... 52 9e-06
UniRef50_A6R5B4 Cluster: NAD(P)H-dependent D-xylose reductase; n... 52 1e-05
UniRef50_Q8EVP7 Cluster: Putative oxidoreductase; n=3; Bacteria|... 52 2e-05
UniRef50_A7HEV1 Cluster: Aldo/keto reductase; n=13; Bacteria|Rep... 51 2e-05
UniRef50_Q54CX8 Cluster: Putative uncharacterized protein; n=1; ... 51 2e-05
UniRef50_Q38Z15 Cluster: Putative aldo/keto reductase; n=2; Bact... 51 3e-05
UniRef50_Q31SB1 Cluster: Putative uncharacterized protein; n=2; ... 50 4e-05
UniRef50_A6C9W8 Cluster: Aldo/keto reductase; n=2; Planctomyceta... 50 4e-05
UniRef50_A5BYJ4 Cluster: Putative uncharacterized protein; n=1; ... 50 4e-05
UniRef50_Q1FEK2 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 50 5e-05
UniRef50_Q0TYC7 Cluster: Predicted protein; n=1; Phaeosphaeria n... 50 5e-05
UniRef50_Q60BI7 Cluster: Oxidoreductase, aldo/keto reductase fam... 50 6e-05
UniRef50_Q6CGE9 Cluster: Similar to sp|P47137 Saccharomyces cere... 50 6e-05
UniRef50_UPI00003C85A8 Cluster: hypothetical protein Faci_030001... 49 8e-05
UniRef50_A7HL79 Cluster: Aldo/keto reductase; n=1; Fervidobacter... 49 8e-05
UniRef50_A7PNT1 Cluster: Chromosome chr8 scaffold_23, whole geno... 49 8e-05
UniRef50_Q93KW0 Cluster: Putative oxidoreductase; n=1; Streptomy... 49 1e-04
UniRef50_UPI00005F9591 Cluster: COG0656: Aldo/keto reductases, r... 48 1e-04
UniRef50_Q660Z5 Cluster: Aldose reductase, putative; n=3; Borrel... 48 1e-04
UniRef50_Q2J8X9 Cluster: Aldo/keto reductase; n=3; Frankia|Rep: ... 48 1e-04
UniRef50_Q8PN61 Cluster: Oxidoreductase; n=5; Proteobacteria|Rep... 48 2e-04
UniRef50_Q81RN9 Cluster: Oxidoreductase, aldo/keto reductase fam... 48 2e-04
UniRef50_Q88ZU3 Cluster: Oxidoreductase; n=1; Lactobacillus plan... 48 2e-04
UniRef50_Q1FGT1 Cluster: Aldo/keto reductase:4Fe-4S ferredoxin, ... 48 2e-04
UniRef50_A6VXX8 Cluster: Aldo/keto reductase; n=2; Marinomonas|R... 48 2e-04
UniRef50_Q88TP1 Cluster: Oxidoreductase; n=3; Bacteria|Rep: Oxid... 47 3e-04
UniRef50_Q7D3N9 Cluster: AGR_pAT_274p; n=3; Proteobacteria|Rep: ... 47 3e-04
UniRef50_A6SUJ2 Cluster: Uncharacterized conserved protein; n=2;... 47 3e-04
UniRef50_Q7Q0Y6 Cluster: ENSANGP00000006086; n=7; Coelomata|Rep:... 47 3e-04
UniRef50_Q2NFN7 Cluster: Predicted oxidoreductase; n=1; Methanos... 47 3e-04
UniRef50_P46905 Cluster: Uncharacterized oxidoreductase yccK; n=... 47 3e-04
UniRef50_UPI0000DAE567 Cluster: hypothetical protein Rgryl_01000... 47 4e-04
UniRef50_Q67NQ1 Cluster: Oxidoreductase; n=1; Symbiobacterium th... 47 4e-04
UniRef50_A0Q648 Cluster: Aldo/keto reductase family protein; n=1... 47 4e-04
UniRef50_Q27ST7 Cluster: Oxidoreductase; n=2; Eukaryota|Rep: Oxi... 47 4e-04
UniRef50_Q97ZZ1 Cluster: Oxidoreductase; n=4; Sulfolobaceae|Rep:... 47 4e-04
UniRef50_Q9X0R5 Cluster: Oxidoreductase, aldo/keto reductase fam... 46 6e-04
UniRef50_Q97UG6 Cluster: Oxidoreductase; n=5; Archaea|Rep: Oxido... 46 6e-04
UniRef50_Q8R6G2 Cluster: Oxidoreductase; n=1; Fusobacterium nucl... 46 8e-04
UniRef50_Q87SA8 Cluster: Oxidoreductase Tas, aldo/keto reductase... 46 8e-04
UniRef50_Q5KYH6 Cluster: K+ channel beta subunit; n=5; Bacteria|... 46 8e-04
UniRef50_Q1VSU3 Cluster: Aryl-alcohol dehydrogenase; n=1; Psychr... 46 8e-04
UniRef50_Q034L5 Cluster: Aryl-alcohol dehydrogenase related enzy... 46 8e-04
UniRef50_Q8Y5Q1 Cluster: Lmo2005 protein; n=34; cellular organis... 46 0.001
UniRef50_A6FYX9 Cluster: Oxidoreductase; n=1; Plesiocystis pacif... 46 0.001
UniRef50_A0ZZJ3 Cluster: Oxidoreductase; n=2; Bifidobacterium ad... 46 0.001
UniRef50_A0K203 Cluster: Aldo/keto reductase; n=2; Arthrobacter|... 46 0.001
UniRef50_A0JVH3 Cluster: Aldo/keto reductase; n=17; Bacteria|Rep... 46 0.001
UniRef50_O43448 Cluster: Voltage-gated potassium channel subunit... 46 0.001
UniRef50_Q8UIN0 Cluster: Oxidoreductase; n=3; Alphaproteobacteri... 45 0.001
UniRef50_Q0LP88 Cluster: Aldo/keto reductase; n=4; Bacteria|Rep:... 45 0.001
UniRef50_A6LWU9 Cluster: Aldo/keto reductase; n=3; Clostridium|R... 45 0.001
UniRef50_A6C2P2 Cluster: Oxidoreductase, aldo/keto reductase fam... 45 0.001
UniRef50_A5EX65 Cluster: Aldo/keto reductase family protein; n=1... 45 0.001
UniRef50_P73573 Cluster: Sll0867 protein; n=15; Bacteria|Rep: Sl... 45 0.002
UniRef50_Q75DD3 Cluster: ABR094Wp; n=1; Eremothecium gossypii|Re... 45 0.002
UniRef50_A4RPC9 Cluster: Putative uncharacterized protein; n=1; ... 45 0.002
UniRef50_Q3WEJ4 Cluster: Aldo/keto reductase; n=9; Bacteria|Rep:... 44 0.002
UniRef50_Q1U6R9 Cluster: Aldo/keto reductase; n=25; Bacilli|Rep:... 44 0.002
UniRef50_A4MAE7 Cluster: Aldo/keto reductase; n=1; Petrotoga mob... 44 0.002
UniRef50_A4CIJ8 Cluster: Putative uncharacterized protein; n=2; ... 44 0.002
UniRef50_A0GAJ5 Cluster: Aldo/keto reductase precursor; n=9; Pro... 44 0.002
UniRef50_A6SJ74 Cluster: Putative uncharacterized protein; n=1; ... 44 0.002
UniRef50_Q8PVL5 Cluster: Oxidoreductase, ALDO/KETO reductase fam... 44 0.002
UniRef50_A3H9H5 Cluster: Aldo/keto reductase; n=2; Archaea|Rep: ... 44 0.002
UniRef50_Q4SFJ7 Cluster: Chromosome 7 SCAF14601, whole genome sh... 44 0.003
UniRef50_Q4WF80 Cluster: Glycerol dehydrogenase (GCY1), putative... 44 0.003
UniRef50_Q8TTK4 Cluster: Aldo/keto reductase; n=28; cellular org... 44 0.003
UniRef50_Q0B0F0 Cluster: Oxidoreductase; n=1; Syntrophomonas wol... 44 0.004
UniRef50_A1SY15 Cluster: Aldo/keto reductase; n=1; Psychromonas ... 44 0.004
UniRef50_A1RJL6 Cluster: Aldo/keto reductase; n=37; Bacteria|Rep... 44 0.004
UniRef50_Q022Y6 Cluster: Aldo/keto reductase precursor; n=2; Sol... 43 0.005
UniRef50_A7GIW7 Cluster: Oxidoreductase, aldo/keto reductase fam... 43 0.005
UniRef50_A6WAE5 Cluster: Aldo/keto reductase; n=1; Kineococcus r... 43 0.005
UniRef50_A0LHW7 Cluster: Aldo/keto reductase precursor; n=1; Syn... 43 0.005
UniRef50_P49261 Cluster: Rho beta-crystallin; n=1; Lepidodactylu... 43 0.005
UniRef50_Q8YAN3 Cluster: Lmo0084 protein; n=11; Listeria monocyt... 43 0.007
UniRef50_Q8A955 Cluster: Aldo/keto reductase; n=8; Bacteroidales... 43 0.007
UniRef50_Q8A1P5 Cluster: Putative oxidoreductase; n=3; Bacteroid... 43 0.007
UniRef50_Q3AD20 Cluster: Oxidoreductase, aldo/keto reductase fam... 43 0.007
UniRef50_Q03UP2 Cluster: Aryl-alcohol dehydrogenase family enzym... 43 0.007
UniRef50_A5VEK4 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:... 43 0.007
UniRef50_A4QYA4 Cluster: Putative uncharacterized protein; n=1; ... 43 0.007
UniRef50_Q31DD1 Cluster: Aldo/keto reductase family; n=5; Prochl... 42 0.009
UniRef50_Q8VV02 Cluster: Putative oxidoreductase; n=1; Streptomy... 42 0.009
UniRef50_Q1YPT8 Cluster: Aldo/keto reductase; n=1; gamma proteob... 42 0.009
UniRef50_A1SGJ5 Cluster: Aldo/keto reductase precursor; n=1; Noc... 42 0.009
UniRef50_A0UVR1 Cluster: Aldo/keto reductase; n=3; Bacteria|Rep:... 42 0.009
UniRef50_A7TT39 Cluster: Putative uncharacterized protein; n=1; ... 42 0.009
UniRef50_Q8F4Y9 Cluster: Aldo/keto reductase family protein; n=4... 42 0.012
UniRef50_Q21F89 Cluster: Aldo/keto reductase; n=1; Saccharophagu... 42 0.012
UniRef50_A6CMV7 Cluster: Putative uncharacterized protein; n=2; ... 42 0.012
UniRef50_A4AP98 Cluster: Putative uncharacterized protein; n=1; ... 42 0.012
UniRef50_A3I0G0 Cluster: Oxidoreductase; n=1; Algoriphagus sp. P... 42 0.012
UniRef50_P42972 Cluster: Uncharacterized oxidoreductase ycsN; n=... 42 0.012
UniRef50_UPI00015B403B Cluster: PREDICTED: similar to CG18547-PA... 42 0.016
UniRef50_A1ZPI5 Cluster: Oxidoreductase; n=1; Microscilla marina... 42 0.016
UniRef50_Q00T51 Cluster: Aldo/keto reductase; n=2; Ostreococcus|... 42 0.016
UniRef50_A3LSR5 Cluster: D-threo-aldose 1-dehydrogenase; n=5; Sa... 42 0.016
UniRef50_UPI0000447325 Cluster: PREDICTED: similar to aldo-keto ... 41 0.022
UniRef50_Q2BBT9 Cluster: Probable oxidoreductase protein; n=2; B... 41 0.022
UniRef50_Q1FGT0 Cluster: Aldo/keto reductase; n=1; Clostridium p... 41 0.022
UniRef50_Q0AL14 Cluster: Aldo/keto reductase; n=1; Maricaulis ma... 41 0.022
UniRef50_A7B2Y7 Cluster: Putative uncharacterized protein; n=1; ... 41 0.022
UniRef50_Q6GIV4 Cluster: Aldo/keto reductase family protein; n=1... 41 0.028
UniRef50_Q39MY8 Cluster: Aldo/keto reductase; n=10; Bacteria|Rep... 41 0.028
UniRef50_Q097V7 Cluster: MocA; n=1; Stigmatella aurantiaca DW4/3... 41 0.028
UniRef50_A7CVG9 Cluster: Aldo/keto reductase; n=1; Opitutaceae b... 41 0.028
UniRef50_A5ZM37 Cluster: Putative uncharacterized protein; n=1; ... 41 0.028
UniRef50_Q011A7 Cluster: Putative aldo/keto reductase family pro... 41 0.028
UniRef50_A1DD54 Cluster: Aldo/keto reductase; n=3; Trichocomacea... 41 0.028
UniRef50_UPI00005100E5 Cluster: COG0667: Predicted oxidoreductas... 40 0.038
UniRef50_Q3AEN5 Cluster: Oxidoreductase, aldo/keto reductase fam... 40 0.038
UniRef50_Q2J7H2 Cluster: Aldo/keto reductase; n=16; Bacteria|Rep... 40 0.038
UniRef50_Q0SJ60 Cluster: Possible aldo/keto reductase; n=50; Bac... 40 0.038
UniRef50_Q0BAM8 Cluster: Aldo/keto reductase; n=1; Burkholderia ... 40 0.038
UniRef50_A5FAZ9 Cluster: Aldo/keto reductase; n=1; Flavobacteriu... 40 0.038
UniRef50_A1RA11 Cluster: Oxidoreductase, aldo/keto reductase fam... 40 0.038
UniRef50_A0YC40 Cluster: Putative uncharacterized protein; n=1; ... 40 0.038
UniRef50_Q9ZUX0 Cluster: Expressed protein; n=11; cellular organ... 40 0.038
UniRef50_Q2NEM6 Cluster: Putative oxidoreductase; n=1; Methanosp... 40 0.038
UniRef50_A0RYR0 Cluster: Oxidoreductase; n=2; cellular organisms... 40 0.038
UniRef50_Q3A7S5 Cluster: Predicted oxidoreductases of the aldo/k... 40 0.050
UniRef50_Q11BU4 Cluster: Aldo/keto reductase; n=11; Proteobacter... 40 0.050
UniRef50_Q08NK7 Cluster: Aldo/keto reductase; n=1; Stigmatella a... 40 0.050
UniRef50_A1SEE9 Cluster: Aldo/keto reductase; n=1; Nocardioides ... 40 0.050
UniRef50_A0ZMD5 Cluster: Tas; n=1; Nodularia spumigena CCY 9414|... 40 0.050
UniRef50_A0YSM3 Cluster: Probable oxidoreductase; n=1; Lyngbya s... 40 0.050
UniRef50_A7T149 Cluster: Predicted protein; n=1; Nematostella ve... 40 0.050
UniRef50_Q0CV71 Cluster: Putative uncharacterized protein; n=2; ... 40 0.050
UniRef50_Q9YBV5 Cluster: Putative uncharacterized protein; n=1; ... 40 0.050
UniRef50_A5UJH5 Cluster: Predicted oxidoreductase, aldo/keto red... 40 0.050
UniRef50_Q97L01 Cluster: Fe-S oxidoreductase; n=4; Clostridium|R... 40 0.066
UniRef50_Q3VQY1 Cluster: Aldo/keto reductase; n=1; Prosthecochlo... 40 0.066
UniRef50_Q3I1P2 Cluster: Aldo-keto oxidoreductase; n=6; Bacteria... 40 0.066
UniRef50_Q1GHE2 Cluster: Aldo/keto reductase; n=8; Alphaproteoba... 40 0.066
UniRef50_A3U5K6 Cluster: Oxidoreductase, aldo/keto reductase fam... 40 0.066
UniRef50_A1ZCJ4 Cluster: Aldo/keto reductase; n=1; Microscilla m... 40 0.066
UniRef50_Q8ZXA1 Cluster: Aldo-keto reductase family protein; n=3... 40 0.066
UniRef50_Q2SL81 Cluster: Predicted oxidoreductase; n=10; Bacteri... 39 0.087
>UniRef50_Q9Y020 Cluster: 3-dehydroecdysone 3beta-reductase
precursor; n=1; Spodoptera littoralis|Rep:
3-dehydroecdysone 3beta-reductase precursor - Spodoptera
littoralis (Egyptian cotton leafworm)
Length = 345
Score = 181 bits (441), Expect = 1e-44
Identities = 89/202 (44%), Positives = 127/202 (62%), Gaps = 1/202 (0%)
Frame = +2
Query: 26 AGFLFCLSALCFTSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY 205
A F+ L+ SA + VP L++ + +P +ALGT+LG G V V+
Sbjct: 4 ASFILLLACCGAMSATIDVPMLKMLNDREMPAIALGTYLGFDKGGAVTSKDKQLRNVVMQ 63
Query: 206 ALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALR 382
A++ GY H DTA Y E +VG A+ K EG +KRE +F+TTKLWN++H+REQV A++
Sbjct: 64 AIDLGYRHFDTAAIYNTEAEVGEAIRMKIDEGVIKREDVFLTTKLWNTHHKREQVAVAMK 123
Query: 383 KSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQ 562
++L L+YVDL+L+HWPIA+ E D N D+L+TWR + KLG TKSIG+SNFN+
Sbjct: 124 ETLNKTGLDYVDLFLMHWPIALNE-DYSHSNTDYLETWRATEEMVKLGYTKSIGLSNFNK 182
Query: 563 EQIQRIIDSGLEKPSALQIELN 628
Q+ ++ KP ALQIE++
Sbjct: 183 LQVATVLQECTIKPVALQIEVH 204
>UniRef50_UPI00015B56A2 Cluster: PREDICTED: similar to GA10458-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
GA10458-PA - Nasonia vitripennis
Length = 569
Score = 172 bits (418), Expect = 7e-42
Identities = 85/196 (43%), Positives = 128/196 (65%), Gaps = 11/196 (5%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VPT+ + G +P++ LGT+L +P G+V + AV YA+E GY H+DTA+ Y E
Sbjct: 3 VPTVTFNDGYKMPMIGLGTFLS-KP-GEVAE-------AVKYAIEVGYRHVDTAFFYENE 53
Query: 260 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
++G A+ +K ++G +KRE IF+TTKLW + H+ ++V+PA +KSLENL +Y+DL+L+HW
Sbjct: 54 KEIGSAIREKINDGTIKREDIFVTTKLWCNSHKEDEVVPACKKSLENLGFDYIDLFLVHW 113
Query: 437 PIAMFENDTL----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
P A D L + D+L+TW+GM + K+ GL +SIG+SNFN EQI R++
Sbjct: 114 PFAFKSGDALTPRDAAGKIEFSDTDYLETWKGMEECKRQGLARSIGLSNFNSEQIARLLS 173
Query: 587 SGLEKPSALQIELNLN 634
S KP Q+E+ +N
Sbjct: 174 SAKIKPVNNQVEVTMN 189
Score = 141 bits (341), Expect = 1e-32
Identities = 66/145 (45%), Positives = 97/145 (66%), Gaps = 8/145 (5%)
Frame = +2
Query: 221 YTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLEN 397
Y HIDTAY Y E +G A+ +K +G +KRE +F+TTKL H+ +V+PA ++SL +
Sbjct: 301 YRHIDTAYLYDNEKYIGNAIREKIKDGTVKREDLFVTTKLSYYAHKESEVVPACKQSLND 360
Query: 398 LNLEYVDLYLIHWPIAMF-------ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNF 556
L L+Y+DLYLIHWPI + LL + D+L+TW+GM + K+ GL +SIG+SNF
Sbjct: 361 LGLDYIDLYLIHWPIRRYFRHNKNASGKLLLSDTDYLETWKGMEECKRQGLARSIGVSNF 420
Query: 557 NQEQIQRIIDSGLEKPSALQIELNL 631
N EQI R++++ KP Q+E++L
Sbjct: 421 NSEQITRLLEAAKIKPVNNQVEVSL 445
>UniRef50_Q8WRT0 Cluster: 3-dehydrecdysone 3b-reductase; n=1;
Trichoplusia ni|Rep: 3-dehydrecdysone 3b-reductase -
Trichoplusia ni (Cabbage looper)
Length = 308
Score = 170 bits (414), Expect = 2e-41
Identities = 92/184 (50%), Positives = 119/184 (64%), Gaps = 2/184 (1%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
P QL+ G IP +ALGT+ G PK QAV++A++AGY HIDTA YG E
Sbjct: 25 PLKQLNDGNAIPSLALGTFGFGDIPK---------VRQAVLWAIQAGYRHIDTAALYGNE 75
Query: 260 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
++VG+ + +GL KRE +F+TTKLWN H R QV+PALR+SL L L YVDLYLIH
Sbjct: 76 EEVGKGIADAIQQGLVKREELFVTTKLWNDKHGRHQVVPALRESLTKLGLSYVDLYLIHS 135
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P A EN +D +D L+TW GM +AKKLGL KSIG+SNF+ + R+I P+ Q
Sbjct: 136 PEATNENGDPVD-IDVLNTWNGMEEAKKLGLAKSIGVSNFDTALLDRLIAGSNTVPAVNQ 194
Query: 617 IELN 628
IE++
Sbjct: 195 IEVH 198
>UniRef50_UPI00015B56A3 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 321
Score = 168 bits (408), Expect = 1e-40
Identities = 84/196 (42%), Positives = 125/196 (63%), Gaps = 11/196 (5%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
V + LS G +PV+ LGTW G +V E AV A++AGY H D A YG E
Sbjct: 5 VDEITLSDGNKVPVLGLGTWQGGNDPDEV-------ENAVKLAIDAGYRHFDCASFYGNE 57
Query: 260 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
++G+A+ +K +G+ KRE +F+ TK+WN ++E V+ A ++SL+ L L Y+DLYL+HW
Sbjct: 58 AEIGKAIQEKIDQGVVKREDLFVVTKVWNDERKQELVVAACKRSLKKLGLGYIDLYLVHW 117
Query: 437 PIA---MFE-------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
P + +++ N LD VD+++TWRGM + KLGLT+SIG+SNFN +Q+ R+++
Sbjct: 118 PFSYPILYQYIVLPTYNAVTLDEVDYIETWRGMEECIKLGLTRSIGVSNFNSQQLTRLLE 177
Query: 587 SGLEKPSALQIELNLN 634
S KP QIEL++N
Sbjct: 178 SASIKPVMNQIELHIN 193
>UniRef50_Q8VC28 Cluster: Aldo-keto reductase family 1 member C13;
n=11; Theria|Rep: Aldo-keto reductase family 1 member
C13 - Mus musculus (Mouse)
Length = 323
Score = 152 bits (369), Expect = 6e-36
Identities = 85/194 (43%), Positives = 120/194 (61%), Gaps = 13/194 (6%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
++L+ G IP + GT+ K K V + E A + AL+ GY H+DTAY Y +E+++
Sbjct: 8 VKLNDGHLIPALGFGTY-----KPKEVPKSKSLEAACL-ALDVGYRHVDTAYAYQVEEEI 61
Query: 269 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
G+A+ K G+ KRE +FITTKLW + E V PAL KSL+ L L+YVDLY++H+P+
Sbjct: 62 GQAIQSKIKAGVVKREDLFITTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVP 121
Query: 446 MFEND----------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 592
M D +LLD VDF DTW + + K GL KSIG+SNFN Q++RI++ G
Sbjct: 122 MKSGDNDFPVNEQGKSLLDTVDFCDTWERLEECKDAGLVKSIGVSNFNHRQLERILNKPG 181
Query: 593 LE-KPSALQIELNL 631
L+ KP Q+E +L
Sbjct: 182 LKYKPVCNQVECHL 195
>UniRef50_Q2LZ66 Cluster: GA19341-PA; n=2; Endopterygota|Rep:
GA19341-PA - Drosophila pseudoobscura (Fruit fly)
Length = 315
Score = 152 bits (368), Expect = 8e-36
Identities = 85/192 (44%), Positives = 116/192 (60%), Gaps = 12/192 (6%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P+ LSSG N+P+V LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PSFLLSSGRNMPMVGLGTW---RSPPEVVA------QAVKDAIDIGYRHFDCAHIYGNEL 54
Query: 263 QVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
VG A+ +K EGL R+ +FIT+KLWN++H+ E V A SL NL ++Y+DLYL+HWP
Sbjct: 55 HVGVAIREKIQEGLVTRDELFITSKLWNTFHKPELVRAACETSLRNLGIDYLDLYLMHWP 114
Query: 440 IAMFENDTL-----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
+A D L +++D+LDTW+ M D GL +IG+SNFN++QI R++
Sbjct: 115 MAYKSGDNLYPTCPDTGKAVFEDIDYLDTWKAMEDLVDSGLVNAIGVSNFNEKQINRLLC 174
Query: 587 SGLEKPSALQIE 622
KP LQIE
Sbjct: 175 LAKLKPVMLQIE 186
>UniRef50_A3U9Y0 Cluster: Aldehyde reductase; n=5;
Bacteroidetes|Rep: Aldehyde reductase - Croceibacter
atlanticus HTCC2559
Length = 316
Score = 150 bits (363), Expect = 3e-35
Identities = 82/192 (42%), Positives = 116/192 (60%), Gaps = 11/192 (5%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
TL+ G +IP + LGTW D ++AV ALE GY HID A Y ED
Sbjct: 3 TLKFRDGDSIPSIGLGTWKSD---------PEDVKKAVKIALENGYKHIDCAAAYDNEDA 53
Query: 266 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VG A + F G +KRE IF+T+KLWN+ H++E VIPAL+K+L++LNL+Y+DLYL+HWP+
Sbjct: 54 VGEAFKESFESGNVKREDIFVTSKLWNNAHKKEDVIPALKKTLKDLNLDYLDLYLMHWPV 113
Query: 443 AM---------FENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 592
A + D L L+ +T MI+AKK GL K +G+SNF++E+++ +
Sbjct: 114 AFKPSVNGFPEKDEDYLSLEEAPLHETLNAMIEAKKQGLIKHVGVSNFSKEKLESLKGKV 173
Query: 593 LEKPSALQIELN 628
E P Q+EL+
Sbjct: 174 EEMPEMNQVELH 185
>UniRef50_Q54B70 Cluster: Aldehyde reductase; n=2; Dictyostelium
discoideum|Rep: Aldehyde reductase - Dictyostelium
discoideum AX4
Length = 297
Score = 148 bits (359), Expect = 1e-34
Identities = 83/192 (43%), Positives = 115/192 (59%), Gaps = 10/192 (5%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPK-GKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
P+ +LSSG IP+V GTW GK V+V AL+AGY HID A Y E
Sbjct: 3 PSFKLSSGHKIPLVGFGTWKAETTLVGKAVEV----------ALDAGYRHIDCAAVYLNE 52
Query: 260 DQVGRALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
+VG A TKKF+ +KRE +FIT+KLWN++H++E V PAL ++L +L L+Y+DLYL+H
Sbjct: 53 KEVGEAFTKKFTTEATVKREDVFITSKLWNTFHKKEHVRPALERTLSDLGLQYLDLYLVH 112
Query: 434 WPIAM--FEND-----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 592
WP+A ND + + V +TW M GL KSIG+SNFN + + ++
Sbjct: 113 WPVAFEYTSNDIQTSGSTQEFVSIRETWEEMEKLVDAGLVKSIGLSNFNVQGLMEVLSYA 172
Query: 593 LEKPSALQIELN 628
KP+A Q+EL+
Sbjct: 173 RIKPAANQVELH 184
>UniRef50_Q7PCV3 Cluster: ENSANGP00000031808; n=9;
Endopterygota|Rep: ENSANGP00000031808 - Anopheles
gambiae str. PEST
Length = 316
Score = 147 bits (355), Expect = 3e-34
Identities = 76/194 (39%), Positives = 112/194 (57%), Gaps = 12/194 (6%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
+VP +G +IP+ LGTW + P G+V Q D A++ GY HID A+ Y
Sbjct: 5 VVPNAIFKNGNSIPMFGLGTW--NSPPGQVAQAVKD-------AIDVGYRHIDCAHVYQN 55
Query: 257 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
E +VG + K +EG+ KRE +F+T+KLWN++H + V A + +L+NL L+Y+DLYLIH
Sbjct: 56 EHEVGEGIAAKIAEGVVKREDLFVTSKLWNTFHRPDLVEGACKTTLQNLKLDYLDLYLIH 115
Query: 434 WPIAMFENDT-----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 580
WP+ E L + D++DTW M GL ++IG+SNFN +Q+QR+
Sbjct: 116 WPVGYQEGTELFPMGPDGKTFLFSDADYVDTWPEMEKLVDAGLVRNIGVSNFNAKQVQRV 175
Query: 581 IDSGLEKPSALQIE 622
+D P+ QIE
Sbjct: 176 LDVARIPPATNQIE 189
>UniRef50_Q7JVH6 Cluster: LD24696p; n=2; Sophophora|Rep: LD24696p -
Drosophila melanogaster (Fruit fly)
Length = 311
Score = 146 bits (353), Expect = 5e-34
Identities = 81/190 (42%), Positives = 117/190 (61%), Gaps = 8/190 (4%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
+ PT++L++G +P + LGTW +D + +AL+ GY H+DTA+ Y
Sbjct: 4 LAPTIRLNNGREMPTLGLGTWKSFE---------SDAYHSTRHALDVGYRHLDTAFVYEN 54
Query: 257 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
E +VG+A+++K +EG+ RE +F+TTKL +H+ V A R SL NL LEYVDLYL+H
Sbjct: 55 EAEVGQAISEKIAEGVVTREEVFVTTKLGGIHHDPALVERACRLSLSNLGLEYVDLYLMH 114
Query: 434 WPIAM-FEND-----TL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 592
P+ F ND TL L +VD+LDTWR M LGLT+SIG+SNFN Q +R++ +
Sbjct: 115 MPVGQKFHNDSNVHGTLELTDVDYLDTWREMEKLVDLGLTRSIGLSNFNAAQTERVLANC 174
Query: 593 LEKPSALQIE 622
+P Q+E
Sbjct: 175 RIRPVVNQVE 184
>UniRef50_Q9VTL0 Cluster: CG6083-PA; n=4; Diptera|Rep: CG6083-PA -
Drosophila melanogaster (Fruit fly)
Length = 322
Score = 145 bits (352), Expect = 7e-34
Identities = 79/193 (40%), Positives = 117/193 (60%), Gaps = 13/193 (6%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P LS+G N+P++ LGTW R +VV QAV A++ GY H D A+ YG E
Sbjct: 4 PNFLLSNGKNMPMLGLGTW---RSPPEVVT------QAVKDAIDIGYRHFDCAHIYGNEA 54
Query: 263 QVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
QVG AL +K EG+ R+ +FIT+KLWN++H+ + V PA S+ NL ++Y++LYL+HWP
Sbjct: 55 QVGAALREKMDEGVVTRDELFITSKLWNTHHKPDLVRPACETSIRNLGVKYLNLYLMHWP 114
Query: 440 IAMFE------------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 583
+A N +++D++DTWR M + GL ++IG+SNFN++Q+ R++
Sbjct: 115 MAYKSGSDNLYPTCPDTNKAAFEDIDYVDTWRAMENLVDEGLCQAIGVSNFNEQQMNRLL 174
Query: 584 DSGLEKPSALQIE 622
KP LQIE
Sbjct: 175 SVAKLKPVVLQIE 187
>UniRef50_Q96UH3 Cluster: Aldehyde reductase; n=13;
Pezizomycotina|Rep: Aldehyde reductase - Coccidioides
posadasii
Length = 314
Score = 143 bits (347), Expect = 3e-33
Identities = 77/191 (40%), Positives = 116/191 (60%), Gaps = 10/191 (5%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T +L++G +IP + GTW Q N E AV+ AL AGY HIDTA YG E
Sbjct: 7 TFRLNTGEDIPAIGFGTW----------QDENAQEDAVLTALSAGYRHIDTAAVYGTEKA 56
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
+GRAL + L R+ +FIT+KLWN+ H E V A+ +SL+NL ++Y+DLYL+HWP A
Sbjct: 57 IGRALARS---RLSRDELFITSKLWNNKHRPEDVEQAIDQSLKNLEIDYLDLYLMHWPAA 113
Query: 446 MFENDTLLD----------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 595
D + ++D++DT++ M K G TK+IGISNF++ +++R+++S
Sbjct: 114 FAPGDDMFPKDSQGNSKTVDIDYVDTYKAMEKLVKSGKTKAIGISNFSKGEMERLLESCS 173
Query: 596 EKPSALQIELN 628
P+ +Q+EL+
Sbjct: 174 IVPAVMQMELH 184
>UniRef50_Q41399 Cluster: Chalcone reductase; n=4;
eudicotyledons|Rep: Chalcone reductase - Sesbania
rostrata
Length = 322
Score = 139 bits (337), Expect = 4e-32
Identities = 70/197 (35%), Positives = 115/197 (58%), Gaps = 10/197 (5%)
Frame = +2
Query: 68 AELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 247
AE +P + L+SG +PV+ +GT + RP V+ + A++ GY H D+A
Sbjct: 2 AEKKIPEVLLNSGHKMPVIGMGTSVESRPSNDVLA------SIFVDAIQVGYRHFDSASV 55
Query: 248 YGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 421
YG E+ +G A++K +GL R+ +FIT+K WN+ + ++PAL+ +L+ L +EYVDL
Sbjct: 56 YGTEEAIGMAVSKAIEQGLIKSRDEVFITSKPWNTDAHHDLIVPALKTTLKKLGMEYVDL 115
Query: 422 YLIHWPIAM---FENDTLLDNVDFL-----DTWRGMIDAKKLGLTKSIGISNFNQEQIQR 577
YLIHWP+ + EN + D L TW+ M + +LGL KSIGI N+ +++ +
Sbjct: 116 YLIHWPVRLRHDLENPVIFSKEDLLPFDIEGTWKAMEECYRLGLAKSIGICNYGTKKLTK 175
Query: 578 IIDSGLEKPSALQIELN 628
+++ P+ Q+E+N
Sbjct: 176 LLEIATIPPAVNQVEMN 192
>UniRef50_Q17DN0 Cluster: Aldo-keto reductase; n=5; Culicidae|Rep:
Aldo-keto reductase - Aedes aegypti (Yellowfever
mosquito)
Length = 324
Score = 139 bits (336), Expect = 6e-32
Identities = 83/196 (42%), Positives = 118/196 (60%), Gaps = 15/196 (7%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+PT++L++G +P + LGT + KG ++ +AV+ A++ G+ HIDTAY Y E
Sbjct: 6 IPTVKLNNGLEMPAIGLGTSMS---KG------DECCKAVMTAIDEGFRHIDTAYNYRNE 56
Query: 260 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
D VGRA+ K EG+ RE +F+TTKLWN++H + V A KSLE+L L+YVDL+LIH
Sbjct: 57 DVVGRAIRAKIEEGVVTREELFVTTKLWNTFHHPDHVPMAFGKSLEHLGLDYVDLFLIHM 116
Query: 437 PIAMF------ENDTLLD---NV-----DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 574
P E T LD NV D++DTW+ M + G SIG+SNFN EQ++
Sbjct: 117 PFGYEFNGWDPEKRTPLDDNGNVLCSDDDYVDTWKAMEKLLESGRVHSIGVSNFNSEQLE 176
Query: 575 RIIDSGLEKPSALQIE 622
RI+ + KP Q+E
Sbjct: 177 RILANCRVKPVTNQVE 192
>UniRef50_UPI0000588153 Cluster: PREDICTED: hypothetical protein;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 333
Score = 138 bits (335), Expect = 8e-32
Identities = 77/192 (40%), Positives = 110/192 (57%), Gaps = 13/192 (6%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
++ L SG +P+V LGTW K K +V A+ A++AGY H D A YG E +
Sbjct: 4 SVTLPSGHAMPLVGLGTW-----KLKADEVAG----AIGAAVDAGYRHFDCALIYGNEKE 54
Query: 266 VGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VG AL + GLKRE +FITTK+WN++H +E V +SL +L L+Y+DLY++HWP+
Sbjct: 55 VGVALREAMQRLGLKREDVFITTKVWNTFHAKEDVAECFNRSLTDLQLDYIDLYIMHWPL 114
Query: 443 --------AMF----ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
MF D + +V +L+TW M D K G KS+G+SNFN +Q+ ++
Sbjct: 115 GFQNLGPTVMFPRTETGDIVYSDVHYLETWSAMEDLVKTGKCKSLGLSNFNSKQLDDVLQ 174
Query: 587 SGLEKPSALQIE 622
PS LQ+E
Sbjct: 175 HSTVPPSVLQVE 186
>UniRef50_Q8K023 Cluster: Aldo-keto reductase family 1 member C18;
n=72; Tetrapoda|Rep: Aldo-keto reductase family 1 member
C18 - Mus musculus (Mouse)
Length = 323
Score = 138 bits (333), Expect = 1e-31
Identities = 75/197 (38%), Positives = 117/197 (59%), Gaps = 13/197 (6%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+ ++L+ G +IPV+ GT+ + + ++ A++ G+ HID ++ Y E
Sbjct: 5 IQKIELNDGHSIPVLGFGTYATEE------HLKKKSMESTKIAIDVGFCHIDCSHLYQNE 58
Query: 260 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
+++G+A+ K +G +KRE IF T+KLW++ H E V P+L SL LNL+YVDLYLIH+
Sbjct: 59 EEIGQAILSKIEDGTVKREDIFYTSKLWSTSHRPELVRPSLENSLRKLNLDYVDLYLIHF 118
Query: 437 PIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
P+++ + LL D VD DTW M K GL KSIG+SNFN+ Q++ I++
Sbjct: 119 PVSLKPGNELLPKDEHGNLIFDTVDLCDTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILN 178
Query: 587 S-GLE-KPSALQIELNL 631
GL+ KP Q+E +L
Sbjct: 179 KPGLKYKPVCNQVECHL 195
>UniRef50_A5E082 Cluster: GCY protein; n=4; Saccharomycetales|Rep:
GCY protein - Lodderomyces elongisporus (Yeast)
(Saccharomyces elongisporus)
Length = 295
Score = 137 bits (332), Expect = 2e-31
Identities = 74/170 (43%), Positives = 106/170 (62%), Gaps = 2/170 (1%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T L++G IP + LGTWL +A + AL+ GY HIDTA YG EDQ
Sbjct: 11 TYTLNNGLKIPAIGLGTWLADEEDAAY--------KATLTALKNGYKHIDTAAAYGNEDQ 62
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VGRA+ G+ R+ IF+TTKLWN H+ + AL +SL+ L LEYVDLYLIHWP++
Sbjct: 63 VGRAIA---DSGVSRDEIFVTTKLWNDQHKDPE--GALDESLKKLGLEYVDLYLIHWPLS 117
Query: 446 MF-ENDTLLDNVDFLDTWRGMIDAKKLG-LTKSIGISNFNQEQIQRIIDS 589
+ + + D+ DF+DTWR + K G K+IG+SNFN++++ ++++S
Sbjct: 118 VDPKTEKPYDDYDFVDTWRNLQKIYKEGKKVKAIGVSNFNKKKLDKLLNS 167
>UniRef50_Q9NAI5 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 316
Score = 136 bits (329), Expect = 4e-31
Identities = 79/195 (40%), Positives = 114/195 (58%), Gaps = 11/195 (5%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
+V +L+L+SG +IP + LGTW +P G+V A+ A+ AGY HID A+ Y
Sbjct: 1 MVQSLKLNSGYSIPAIGLGTWQS-KP-GEVAA-------AIKTAVAAGYRHIDCAHVYQN 51
Query: 257 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
+ +VG AL + EG +KRE +FIT+K+WN++H + + L +L L YVDL LIH
Sbjct: 52 QKEVGEALKEILDEGKVKREELFITSKVWNTFHSEAKAHENIDIILSDLQLSYVDLMLIH 111
Query: 434 WPIAMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 583
WP E L +VD+L+TW+ A+K G +SIG+SNF QIQR+
Sbjct: 112 WPQGYAEGAELFPAGENGKMRYSDVDYLETWKAFEAAQKAGKCRSIGLSNFTHSQIQRVW 171
Query: 584 DSGLEKPSALQIELN 628
D+ KP+ LQ+EL+
Sbjct: 172 DAAEVKPACLQVELH 186
>UniRef50_Q5FK98 Cluster: Oxidoreductase; n=8; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus acidophilus
Length = 285
Score = 135 bits (327), Expect = 7e-31
Identities = 74/181 (40%), Positives = 108/181 (59%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T L++G IP++ GTW P G+V E++V+ AL GY HIDTA YG ED
Sbjct: 9 TYTLNNGVKIPIIGFGTW--QTPDGEVA------EESVLAALNCGYRHIDTASAYGNEDS 60
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VGRA+ K G+ R +FITTKLWNS H E+ A+ +SL +L L+Y+D+YLIHWP
Sbjct: 61 VGRAIQKS---GINRHELFITTKLWNSDHGYEKTKKAIDQSLLDLKLDYLDMYLIHWPNP 117
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 625
D + ++ ++WR M +A + G ++IG+SNF + + ++++ KP QI L
Sbjct: 118 SSMRDHWAE-IN-AESWRAMEEAVRAGKIRAIGVSNFRKHHLDALMETAEIKPVVNQIFL 175
Query: 626 N 628
N
Sbjct: 176 N 176
>UniRef50_Q6TY50 Cluster: Reductase 2; n=10; Magnoliophyta|Rep:
Reductase 2 - Hydrangea macrophylla (Bigleaf hydrangea)
Length = 321
Score = 135 bits (326), Expect = 1e-30
Identities = 76/193 (39%), Positives = 116/193 (60%), Gaps = 10/193 (5%)
Frame = +2
Query: 80 VPTLQLSSGGN-IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
+P + LSSGG +PV+ LGT + V+ +AV AL+ GY H DTA Y
Sbjct: 5 IPEVPLSSGGRKMPVLGLGTAADPPVDPETVR------KAVTEALKLGYRHFDTAALYNS 58
Query: 257 EDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 430
E +G A+ + EGL R+ +FIT+KLW S RE V PAL+K+L+NL LEY+D+YLI
Sbjct: 59 EQPLGDAIAEALGEGLIKSRDELFITSKLWCSDAHRENVEPALQKTLKNLKLEYIDMYLI 118
Query: 431 HWPIAM----FENDTLLDN---VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 589
HWP++ +E ++ +D+ W M + +KLGLTK+IG+SNF+ +++ ++ +
Sbjct: 119 HWPVSSKPGNYEYPIKKEDFLQMDYKSVWEAMEECQKLGLTKAIGVSNFSCKKLSDVLAN 178
Query: 590 GLEKPSALQIELN 628
P+ Q+E+N
Sbjct: 179 AKVPPAVNQVEVN 191
>UniRef50_Q968S3 Cluster: Aldoketoreductase-like protein; n=1;
Orconectes limosus|Rep: Aldoketoreductase-like protein -
Orconectes limosus (Spinycheek crayfish)
Length = 336
Score = 135 bits (326), Expect = 1e-30
Identities = 82/195 (42%), Positives = 112/195 (57%), Gaps = 11/195 (5%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
+PT+ L+SG +IPV+ LGT LG K VT E A LE GY H D+A YG
Sbjct: 11 IPTILLNSGSHIPVMGLGTGSLGRNGKMSEEAVTAVLETA----LECGYRHFDSAAYYGN 66
Query: 257 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
E +G+ L + SEG +KRE +FITTKL + + V L+KSL+NL L YVDLYL+H
Sbjct: 67 EAIIGQVLRRWISEGKVKREELFITTKLPTRGNREKDVARFLQKSLDNLRLPYVDLYLVH 126
Query: 434 WPIAMFEND---------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
+P + + D T+ D WR M G TK+IG+SNFN +Q+QRII
Sbjct: 127 YPCGILDTDRERLSADEVTVDPTTDIHAIWRAMEAQLAAGKTKNIGLSNFNADQVQRIIK 186
Query: 587 SGLEKPSALQIELNL 631
+P+ LQ+E+++
Sbjct: 187 GCQVRPAVLQVEVHV 201
>UniRef50_Q7QK25 Cluster: ENSANGP00000019775; n=2; Anopheles gambiae
str. PEST|Rep: ENSANGP00000019775 - Anopheles gambiae
str. PEST
Length = 319
Score = 134 bits (325), Expect = 1e-30
Identities = 75/199 (37%), Positives = 120/199 (60%), Gaps = 16/199 (8%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VPT++ S+G IPV+ GT+L KG+ V++ A++ GY HIDTA+ Y E
Sbjct: 5 VPTVRFSNGYEIPVLGYGTYLAQ--KGQCVELVKK-------AIDLGYRHIDTAFLYENE 55
Query: 260 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
++G+A+ K +EG ++RE +F+TTKLWN++H+ + V A R+S + L++ Y+DL+L+H
Sbjct: 56 VEIGQAIRDKIAEGVIRREDVFVTTKLWNTFHDPQHVEEAFRRSFDMLDIGYIDLFLMHS 115
Query: 437 PIAM----FE----------NDTLLDNVDFLDTWRGMIDAKKL-GLTKSIGISNFNQEQI 571
P+ + +E + L +VD+++TW+ M G +SIG+SNFN EQI
Sbjct: 116 PMGVQFSGYEYADMQPKDAAGNMLFSDVDYVETWKAMEKLVTAGGRVRSIGLSNFNSEQI 175
Query: 572 QRIIDSGLEKPSALQIELN 628
+RI+ KP Q+E N
Sbjct: 176 ERILQIATVKPVNNQVEAN 194
>UniRef50_P14550 Cluster: Alcohol dehydrogenase [NADP+]; n=44;
Bilateria|Rep: Alcohol dehydrogenase [NADP+] - Homo
sapiens (Human)
Length = 325
Score = 134 bits (325), Expect = 1e-30
Identities = 75/188 (39%), Positives = 106/188 (56%), Gaps = 12/188 (6%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L +G +P++ LGTW K + QV + AV YAL GY HID A YG E ++G
Sbjct: 8 LHTGQKMPLIGLGTW-----KSEPGQV----KAAVKYALSVGYRHIDCAAIYGNEPEIGE 58
Query: 275 ALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
AL + G + RE +F+T+KLWN+ H E V PALRK+L +L LEY+DLYL+HWP A
Sbjct: 59 ALKEDVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAF 118
Query: 449 FENDT----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 598
D D+ + +TW+ + GL +++G+SNFN QI I+
Sbjct: 119 ERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASV 178
Query: 599 KPSALQIE 622
+P+ LQ+E
Sbjct: 179 RPAVLQVE 186
>UniRef50_Q0VGY1 Cluster: 3-alpha-hydroxysteroid dehydrogenase;
n=13; Tetrapoda|Rep: 3-alpha-hydroxysteroid
dehydrogenase - Xenopus tropicalis (Western clawed frog)
(Silurana tropicalis)
Length = 324
Score = 134 bits (324), Expect = 2e-30
Identities = 75/195 (38%), Positives = 116/195 (59%), Gaps = 14/195 (7%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHR-PKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
++L+ G +PV+ GT+ + PK E+ A++ GY HID A+ YG E++
Sbjct: 9 VELNDGHKMPVIGFGTYAPPKFPKSLA-------EEGTKVAIDVGYRHIDCAFLYGNEEE 61
Query: 266 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VGRA+ K ++G +KRE +F T KLW++ H E+V PAL KSL++L L+Y+DL++IH P+
Sbjct: 62 VGRAIRAKIADGTVKREDVFYTGKLWSTSHTPERVRPALEKSLKDLQLDYMDLFIIHMPM 121
Query: 443 AMFENDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-S 589
D L N D DTW+ + K GL +SIG+SNFN +Q++ I++
Sbjct: 122 EFKPGDDLFPADENGKFIYHNTDLRDTWKALEKCKDAGLVRSIGVSNFNHKQLELILNMP 181
Query: 590 GLE-KPSALQIELNL 631
GL+ KP Q+E ++
Sbjct: 182 GLKYKPVCNQVECHV 196
>UniRef50_UPI000065D0BD Cluster: Homolog of Homo sapiens "AKR1B1
protein.; n=1; Takifugu rubripes|Rep: Homolog of Homo
sapiens "AKR1B1 protein. - Takifugu rubripes
Length = 330
Score = 101 bits (241), Expect(2) = 2e-30
Identities = 54/123 (43%), Positives = 78/123 (63%), Gaps = 1/123 (0%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
++P++ L++G +PV+ LGTW GK V T +AV A+ AGY HIDTAY Y
Sbjct: 1 MIPSVTLNTGALMPVLGLGTW----KSGKGV-----TTEAVKVAIGAGYRHIDTAYVYEN 51
Query: 257 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
E +VG + +G+ KRE +FI +KLW ++H V A K+L +LNL+YVDLYL+H
Sbjct: 52 ETEVGAGVQAMIDQGVVKREELFIVSKLWCTFHTPSLVRGACEKTLSSLNLDYVDLYLMH 111
Query: 434 WPI 442
+P+
Sbjct: 112 FPM 114
Score = 54.0 bits (124), Expect(2) = 2e-30
Identities = 27/58 (46%), Positives = 38/58 (65%), Gaps = 2/58 (3%)
Frame = +2
Query: 455 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 622
N + D FLDTW M + GL K+IGISNFN++QI+ +++ GL+ KP+ QIE
Sbjct: 153 NQLICDGTSFLDTWEAMEELVDDGLAKAIGISNFNKDQIEAVLNKPGLKHKPATNQIE 210
>UniRef50_Q23320 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 320
Score = 133 bits (321), Expect = 4e-30
Identities = 83/185 (44%), Positives = 108/185 (58%), Gaps = 1/185 (0%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VP LS+G +P + LGTW +GK V + N A+ AGY HIDTA Y E
Sbjct: 5 VPIFTLSNGVLMPSIGLGTWQMTGEEGKTV-IRN--------AVLAGYRHIDTATLYQNE 55
Query: 260 DQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
Q+G AL + F+EG LKRE IFITTK + + V ALR SL+ L L+YVDLYL H
Sbjct: 56 HQIGDALAELFAEGILKREDIFITTKAFCHEVAPDVVEEALRNSLKRLRLDYVDLYLAHI 115
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P + ++ + +V D WRG LGLTK+IG+SNFN+ QI RI++ A Q
Sbjct: 116 PASTKDDGSFRSDVKVEDIWRGFEKVYGLGLTKAIGVSNFNESQIVRIMNIQKVPIHASQ 175
Query: 617 IELNL 631
+EL+L
Sbjct: 176 LELHL 180
>UniRef50_Q2UGR1 Cluster: Aldo/keto reductase family proteins; n=2;
Ascomycota|Rep: Aldo/keto reductase family proteins -
Aspergillus oryzae
Length = 323
Score = 133 bits (321), Expect = 4e-30
Identities = 82/194 (42%), Positives = 114/194 (58%), Gaps = 15/194 (7%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T +L+SG NIP + LGTWL +P ++ E AV AL AGY HID A Y E++
Sbjct: 6 TFKLNSGYNIPAIGLGTWLS-KP--------HEVENAVEAALRAGYRHIDAAACYQNENE 56
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VG K G+ R+ IFIT+KLWN++H E V A+ K+L++L +Y+DLYLIHWP+A
Sbjct: 57 VGNGWKKS---GVPRDQIFITSKLWNTHHHPEHVEEAVNKTLKDLQTDYLDLYLIHWPVA 113
Query: 446 M-FENDTL-----------LDNVDFLDTWRG---MIDAKKLGLTKSIGISNFNQEQIQRI 580
N+TL L NV DTW +++AKK+ +SIGISNF Q++I +
Sbjct: 114 FEHTNETLTPIDPVTKRFRLANVPIADTWAALEKLVEAKKI---RSIGISNFTQDKIDDL 170
Query: 581 IDSGLEKPSALQIE 622
+ + P+ QIE
Sbjct: 171 LKTAKIPPAVNQIE 184
>UniRef50_Q2S340 Cluster: Aldehyde reductase; n=10; Bacteria|Rep:
Aldehyde reductase - Salinibacter ruber (strain DSM
13855)
Length = 321
Score = 132 bits (319), Expect = 7e-30
Identities = 74/191 (38%), Positives = 113/191 (59%), Gaps = 10/191 (5%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
++ +G +P++ LGTW P G+V + AV ALEAGY H+D A Y E +
Sbjct: 3 SISFENGDEMPMIGLGTWKS--PPGEVYE-------AVTTALEAGYRHVDCAPIYKNETE 53
Query: 266 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VG AL+ F G ++R+ +++T+KLWN+ H + V PAL ++L +L L+ +DLYLIHWP+
Sbjct: 54 VGAALSDSFDAGGIRRDDVWVTSKLWNNAHHPDDVRPALEQTLSDLRLDALDLYLIHWPV 113
Query: 443 AMF-ENDTLLDNVDFL--------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 595
A+ E D DF+ +TW M KK GL + IG+SNF+ +Q I+D+G
Sbjct: 114 ALQPEVDFPESPDDFVSPEAVPLTETWAAMEALKKDGLVRHIGVSNFSVPNLQMILDAGE 173
Query: 596 EKPSALQIELN 628
+P Q+E++
Sbjct: 174 VRPEMNQVEMH 184
>UniRef50_Q7PLK6 Cluster: CG40064-PA; n=1; Drosophila
melanogaster|Rep: CG40064-PA - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 132 bits (319), Expect = 7e-30
Identities = 68/156 (43%), Positives = 93/156 (59%), Gaps = 12/156 (7%)
Frame = +2
Query: 194 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVI 370
AV A+E G+ H DTAY Y E ++G AL + G + RE+IF+TTKLWN++H+ V
Sbjct: 49 AVHCAIETGFRHFDTAYYYENEKEIGEALRTQIKMGNISRENIFLTTKLWNTHHDPRDVR 108
Query: 371 PALRKSLENLNLEYVDLYLIHWPIA-----------MFENDTLLDNVDFLDTWRGMIDAK 517
K LE L Y+DLYL+H+P+ M ++ +D+LDTWR M +
Sbjct: 109 RICEKQLELLGFSYIDLYLMHFPVGYKYVCDEILMPMSGDELQTVEIDYLDTWRAMENLV 168
Query: 518 KLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 625
KLG+ +SIG+SNFN EQIQRII KP Q+E+
Sbjct: 169 KLGMVRSIGLSNFNMEQIQRIIQCSSSKPVVNQVEI 204
>UniRef50_P26690 Cluster: NAD(P)H-dependent 6'-deoxychalcone
synthase; n=3; Papilionoideae|Rep: NAD(P)H-dependent
6'-deoxychalcone synthase - Glycine max (Soybean)
Length = 315
Score = 132 bits (319), Expect = 7e-30
Identities = 68/159 (42%), Positives = 100/159 (62%), Gaps = 9/159 (5%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 358
DT++A+I A++ GY H DTA YG E +G AL + GL R+ +F+T+KLW + +
Sbjct: 37 DTKEAIIEAVKQGYRHFDTAAAYGSEQALGEALKEAIHLGLVSRQDLFVTSKLWVTENHP 96
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGMIDA 514
V+PALRKSL+ L LEY+DLYLIHWP++ E + LL D W M +
Sbjct: 97 HLVLPALRKSLKTLQLEYLDLYLIHWPLSSQPGKFSFPIEVEDLLP-FDVKGVWESMEEC 155
Query: 515 KKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNL 631
+KLGLTK+IG+SNF+ +++Q ++ +P Q+E+NL
Sbjct: 156 QKLGLTKAIGVSNFSVKKLQNLLSVATIRPVVDQVEMNL 194
>UniRef50_UPI00015B40FA Cluster: PREDICTED: similar to CG2767-PA;
n=2; Nasonia vitripennis|Rep: PREDICTED: similar to
CG2767-PA - Nasonia vitripennis
Length = 356
Score = 132 bits (318), Expect = 9e-30
Identities = 82/193 (42%), Positives = 109/193 (56%), Gaps = 13/193 (6%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T++LSSG ++P++ LGTW P + E AV ALE+GY HIDTA+ YG E+
Sbjct: 27 TIKLSSGHDMPMIGLGTW--QMPPEAI-------EVAVTAALESGYRHIDTAFTYGNEEA 77
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
+G+ L K F +G KRE +FITTKL E V L+ SLE L LEYV++YLIH P A
Sbjct: 78 IGKTLKKWFDKGGKREDLFITTKLPPIGMRAEYVESYLKLSLEKLGLEYVNMYLIHKPFA 137
Query: 446 MF------------ENDTLLD-NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
+ +LD + D + WR M K G +SIG+SNFN+ Q+ + +
Sbjct: 138 FVKDKYKYEPALNPDGSVVLDTDTDHVAIWRAMEKQVKAGRVRSIGLSNFNKSQLLNVYE 197
Query: 587 SGLEKPSALQIEL 625
KPS LQIEL
Sbjct: 198 HAEIKPSNLQIEL 210
>UniRef50_Q8CI22 Cluster: 2310005E10Rik protein; n=30;
Tetrapoda|Rep: 2310005E10Rik protein - Mus musculus
(Mouse)
Length = 316
Score = 132 bits (318), Expect = 9e-30
Identities = 76/189 (40%), Positives = 108/189 (57%), Gaps = 13/189 (6%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L +G +P+V LGTW P KV +AV A++AGY HID AY Y E +VG
Sbjct: 7 LLTGAKMPIVGLGTWKS--PPAKV-------REAVKVAIDAGYRHIDCAYVYQNESEVGE 57
Query: 275 ALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 451
A+ +K E +KRE +FI +KLW+++ E+ V A + +L +L L+Y+DLYLIHWP
Sbjct: 58 AIQEKIQEKAVKREDLFIVSKLWSTFFEKSLVKKAFQNTLSDLKLDYLDLYLIHWPQGFQ 117
Query: 452 ENDTLLDNVD----------FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE 598
+ L D FLD W M + GL K++G+SNFN QI+R+++ GL+
Sbjct: 118 SGNVFLPTDDKGSILSSKYTFLDAWEAMEELVDQGLVKALGVSNFNHFQIERLLNKPGLK 177
Query: 599 -KPSALQIE 622
KP Q+E
Sbjct: 178 HKPVTNQVE 186
>UniRef50_P45376 Cluster: Aldose reductase; n=21; Bilateria|Rep:
Aldose reductase - Mus musculus (Mouse)
Length = 316
Score = 131 bits (317), Expect = 1e-29
Identities = 77/191 (40%), Positives = 112/191 (58%), Gaps = 13/191 (6%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
L+L++G +P + LGTW P G+V + AV A++ GY HID A Y E +V
Sbjct: 5 LELNNGTKMPTLGLGTWKS--PPGQVTE-------AVKVAIDLGYRHIDCAQVYQNEKEV 55
Query: 269 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
G AL +K E + KR+ +FI +KLW ++H++ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVALQEKLKEQVVKRQDLFIVSKLWCTFHDKSMVKGAFQKTLSDLQLDYLDLYLIHWPTG 115
Query: 446 M----------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 592
+ + + DF+DTW M GL K+IG+SNFN QI+RI++ G
Sbjct: 116 FKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKTIGVSNFNPLQIERILNKPG 175
Query: 593 LE-KPSALQIE 622
L+ KP+ QIE
Sbjct: 176 LKYKPAVNQIE 186
>UniRef50_UPI00015B4B22 Cluster: PREDICTED: similar to GA15457-PA;
n=1; Nasonia vitripennis|Rep: PREDICTED: similar to
GA15457-PA - Nasonia vitripennis
Length = 388
Score = 131 bits (316), Expect = 2e-29
Identities = 80/192 (41%), Positives = 111/192 (57%), Gaps = 11/192 (5%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
V L+LSSG IP V LGT +++ ++ + A+ ALE GY HIDTA+ Y E
Sbjct: 23 VEKLKLSSGHEIPAVGLGT--------STIKL-DEMDNAISSALENGYRHIDTAFSYDNE 73
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+G+ L K F +G KRE IFIT+KL + + + V L++SL++L L+YVD+YLIH P
Sbjct: 74 AAIGKILKKWFDKGGKREDIFITSKLPSQGNRPQSVETYLKRSLKDLGLDYVDMYLIHTP 133
Query: 440 IAMFENDT-----------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
A+ E + L D+VD W+ M K G KSIG+SNFNQ Q+ I +
Sbjct: 134 FAVKEGENLSSKQDKDGNDLFDDVDHKALWKAMERQVKEGRAKSIGLSNFNQSQVLNIYN 193
Query: 587 SGLEKPSALQIE 622
+ KPS LQ+E
Sbjct: 194 NAEIKPSNLQVE 205
>UniRef50_Q88SL1 Cluster: Oxidoreductase; n=51; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 286
Score = 131 bits (316), Expect = 2e-29
Identities = 77/191 (40%), Positives = 107/191 (56%), Gaps = 2/191 (1%)
Frame = +2
Query: 62 TSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTA 241
T+ + T L++G IP+V GTW P G+V +V+ AL+AGY HIDTA
Sbjct: 2 TALTKLTDTYTLNNGTKIPIVGFGTW--QTPDGQVAY------DSVLAALKAGYRHIDTA 53
Query: 242 YKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 421
YG E+ VG+A+ G+ RE +F+TTKLWN+ H + AL SL L L+YVDL
Sbjct: 54 AAYGNEESVGKAIA---DSGVAREDLFVTTKLWNADHGYDAAKKALDTSLAKLGLDYVDL 110
Query: 422 YLIHW--PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 595
YLIHW P AM +N L+ DTWR M +A ++IG+SNF + + ++ +
Sbjct: 111 YLIHWPNPAAMRDNWEQLN----ADTWRAMEEAYTARKARAIGVSNFRPKHLDALLKTAK 166
Query: 596 EKPSALQIELN 628
P+ QI LN
Sbjct: 167 VVPAVNQIFLN 177
>UniRef50_Q5BKE9 Cluster: LOC594893 protein; n=5; Xenopus
tropicalis|Rep: LOC594893 protein - Xenopus tropicalis
(Western clawed frog) (Silurana tropicalis)
Length = 345
Score = 130 bits (314), Expect = 3e-29
Identities = 83/207 (40%), Positives = 118/207 (57%), Gaps = 28/207 (13%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWL------------GH---RPKGKVVQVTNDTEQAVIYALEAG 220
++QL G +PVVA GT+ GH G +D A AL+ G
Sbjct: 8 SIQLHDGRWMPVVAFGTFYPFTFPGDSQANPGHCAGTKHGTEKSFIDDVRVATKMALDLG 67
Query: 221 YTHIDTAYKYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLEN 397
Y H+D A+ Y E VG+A +KF++G LKRE +F T+KLWN++H+ V PAL K+L
Sbjct: 68 YRHVDGAFLYSSETGVGQAFREKFADGTLKREDLFYTSKLWNTFHQPHLVRPALEKTLSF 127
Query: 398 LNLEYVDLYLIHWPIA------MF---ENDT-LLDNVDFLDTWRGMIDAKKLGLTKSIGI 547
L ++YVDLYLIH P++ +F E+ T D D L TW+ + + + GL KSIG+
Sbjct: 128 LQMDYVDLYLIHMPMSFKPAEELFPKNEDGTCAFDQPDLLQTWQALEECRDAGLVKSIGV 187
Query: 548 SNFNQEQIQRIIDS-GLE-KPSALQIE 622
SNFN+ Q++ I++ GL+ KP QIE
Sbjct: 188 SNFNRRQLEMILNKPGLKYKPVCNQIE 214
>UniRef50_P15121 Cluster: Aldose reductase; n=72; Eumetazoa|Rep:
Aldose reductase - Homo sapiens (Human)
Length = 316
Score = 130 bits (314), Expect = 3e-29
Identities = 79/191 (41%), Positives = 114/191 (59%), Gaps = 13/191 (6%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
L L++G +P++ LGTW P G+V + AV A++ GY HID A+ Y E++V
Sbjct: 5 LLLNNGAKMPILGLGTWKS--PPGQVTE-------AVKVAIDVGYRHIDCAHVYQNENEV 55
Query: 269 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
G A+ +K E + KRE +FI +KLW +YHE+ V A +K+L +L L+Y+DLYLIHWP
Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTG 115
Query: 446 ------MFEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 592
F D + + + LDTW M + GL K+IGISNFN Q++ I++ G
Sbjct: 116 FKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPG 175
Query: 593 LE-KPSALQIE 622
L+ KP+ QIE
Sbjct: 176 LKYKPAVNQIE 186
>UniRef50_Q8SSK6 Cluster: ALDOSE REDUCTASE; n=1; Encephalitozoon
cuniculi|Rep: ALDOSE REDUCTASE - Encephalitozoon
cuniculi
Length = 301
Score = 129 bits (312), Expect = 5e-29
Identities = 80/196 (40%), Positives = 113/196 (57%), Gaps = 11/196 (5%)
Frame = +2
Query: 74 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 253
+I T +L++G IP V LGTW G + + E A+ AL GY HIDTA+ YG
Sbjct: 1 MICKTQKLNNGKEIPTVGLGTW-GMEDEAVL-------EGAIRNALSLGYRHIDTAFIYG 52
Query: 254 IEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 430
E +G L K F EG ++R+ +FIT+KLWN++H + LR+SL +L ++YVDLYLI
Sbjct: 53 NEKMIGNILKKLFDEGVVQRKDLFITSKLWNTFHGCPE--DGLRRSLNDLQMDYVDLYLI 110
Query: 431 HWPIAM-------FENDTLLDNV---DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 580
HWP+ E+ NV D + W+ M LGL KSIGISNF + ++I
Sbjct: 111 HWPVTFDPAPDGTVESCGKKYNVGKFDAVGVWKKMEALVDLGLAKSIGISNFGKANTEKI 170
Query: 581 IDSGLEKPSALQIELN 628
+ + P+A+QIEL+
Sbjct: 171 LGTCRICPAAIQIELH 186
>UniRef50_A7CUW0 Cluster: 2,5-didehydrogluconate reductase; n=6;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Opitutaceae bacterium TAV2
Length = 334
Score = 129 bits (311), Expect = 6e-29
Identities = 78/194 (40%), Positives = 108/194 (55%), Gaps = 1/194 (0%)
Frame = +2
Query: 50 ALCFTSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYT 226
A C+T ++PTL LS G +IP + LG W Q+ +D I A AGY
Sbjct: 51 AWCYTMR--MIPTLPLSDGTSIPQLGLGVW----------QMPDDGAGVPIQAAFNAGYR 98
Query: 227 HIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNL 406
IDTA YG E+ VGRA+ + GL R+ ++ITTK+WNS + + A+R+SL L L
Sbjct: 99 AIDTAPIYGNEEGVGRAIR---ASGLPRKELYITTKVWNSAQGYDSTLRAVRESLGRLQL 155
Query: 407 EYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
EYVDLYLIHWP+ + ++DTW+ + K GL +SIG+SNF +QR+ D
Sbjct: 156 EYVDLYLIHWPVPKIDR--------YVDTWKALAKIKADGLARSIGVSNFTPVYLQRLFD 207
Query: 587 SGLEKPSALQIELN 628
P Q+EL+
Sbjct: 208 ETGIVPVVNQVELH 221
>UniRef50_A2R6Z3 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=9; Pezizomycotina|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 345
Score = 128 bits (310), Expect = 8e-29
Identities = 75/191 (39%), Positives = 108/191 (56%), Gaps = 12/191 (6%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T +L++G ++P V LGTW + ++ AVI AL+ GY HID A YG E +
Sbjct: 6 TFKLNTGYDMPAVGLGTWQSKK---------DEVRDAVIAALKCGYRHIDAAAVYGNEQE 56
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VG + G+ RE IF+T+KLWN++H E V A+ KSL +L +Y+DLYLIHWP+A
Sbjct: 57 VGDGMRLS---GVPREEIFLTSKLWNTHHHPENVEEAVDKSLADLQTDYLDLYLIHWPVA 113
Query: 446 ----------MFENDTLLDNVD--FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 589
+ E L+D VD DTW M + G +SIG+SNF +E+I+ ++ +
Sbjct: 114 FRYSTTTIQPVNEQTGLIDVVDVPIKDTWAAMEKLVEKGKVRSIGVSNFTREKIEELLKT 173
Query: 590 GLEKPSALQIE 622
P+ QIE
Sbjct: 174 AKITPAVNQIE 184
>UniRef50_A2EYY6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=9; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 308
Score = 128 bits (309), Expect = 1e-28
Identities = 78/190 (41%), Positives = 112/190 (58%), Gaps = 17/190 (8%)
Frame = +2
Query: 113 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVGRALTKK 289
IP + LGTW R + D A+ YA+ EAGY HID A Y ED VG+AL +
Sbjct: 4 IPTIGLGTWKSPR--------SEDLVNAITYAIKEAGYVHIDCALCYENEDIVGQALQQC 55
Query: 290 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN---- 457
+ G+KRE+I+IT+KLWN++H E V A RK+L++L L+Y+DLYL+H+P A F+N
Sbjct: 56 WDSGIKRENIWITSKLWNTHHRLEIVEEACRKTLKDLRLDYLDLYLMHYPFA-FQNTGIG 114
Query: 458 ----------DTLLDN-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-K 601
+T+ D+ V +DTW+ M + GL K IG+SN+ Q++R+ S +
Sbjct: 115 GSLNPLDEKGNTIFDDGVSLIDTWKAMEKLVEKGLVKRIGVSNWTINQLERLKYSDAKTT 174
Query: 602 PSALQIELNL 631
P Q+E NL
Sbjct: 175 PYTNQVEFNL 184
>UniRef50_Q96JD6 Cluster: Aldo-keto reductase family 1 member C-like
protein 2; n=37; Euteleostomi|Rep: Aldo-keto reductase
family 1 member C-like protein 2 - Homo sapiens (Human)
Length = 320
Score = 94.7 bits (225), Expect(2) = 1e-28
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +2
Query: 107 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 286
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 287 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 54.8 bits (126), Expect(2) = 1e-28
Identities = 28/58 (48%), Positives = 37/58 (63%), Gaps = 2/58 (3%)
Frame = +2
Query: 455 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 622
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QIE
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQIE 196
>UniRef50_Q03TW0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 293
Score = 127 bits (307), Expect = 2e-28
Identities = 73/181 (40%), Positives = 102/181 (56%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+P L +++G IP + LG + V DT+ A+ +AL AGY HIDTA YG E
Sbjct: 11 IPDLPMNNGHQIPQLGLGVFQ--------VDNAEDTKNAIKWALAAGYRHIDTAAYYGNE 62
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
VG A+ + + R+ IF+T+KLWNS ++ A +++L+ L L+Y+DLYLIHWP
Sbjct: 63 QWVGEAIRES---DVPRDQIFVTSKLWNSVRGYDETQAAFQETLDKLGLDYLDLYLIHWP 119
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
+LD+WR M D K G K+IG+SNFNQ Q+ I+ G KP QI
Sbjct: 120 AP-----------GYLDSWRAMEDLYKAGKIKNIGVSNFNQTQMADILAHGTVKPVVDQI 168
Query: 620 E 622
E
Sbjct: 169 E 169
>UniRef50_UPI000023D0F1 Cluster: hypothetical protein FG03517.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG03517.1 - Gibberella zeae PH-1
Length = 364
Score = 127 bits (306), Expect = 3e-28
Identities = 71/172 (41%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Frame = +2
Query: 110 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 289
+IP LGTWL KG VV AV YAL+ GY HIDTA + ED+VG+ +
Sbjct: 59 DIPAFGLGTWLAG--KGVVVP-------AVEYALKGGYRHIDTALIWRNEDEVGKGIK-- 107
Query: 290 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF-ENDTL 466
+ G+ R+ I++T KLWN+ H E V A+ S+ NL +EY+DLYLIH+P+A E +
Sbjct: 108 -ASGVSRDEIWVTGKLWNTDHRPELVRKAIETSIANLGVEYLDLYLIHYPVAWVPETRDV 166
Query: 467 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
+N +DTW+ M + + GLT++IG SNF + I +I+ +P A + E
Sbjct: 167 DNNTSLIDTWKAMEELVRAGLTRNIGFSNFAPKDINKILKIASIQPYAHEFE 218
>UniRef50_Q01J82 Cluster: OSIGBa0152K17.5 protein; n=28;
Magnoliophyta|Rep: OSIGBa0152K17.5 protein - Oryza
sativa (Rice)
Length = 323
Score = 127 bits (306), Expect = 3e-28
Identities = 73/192 (38%), Positives = 105/192 (54%), Gaps = 9/192 (4%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VP + L G P+ A+G +G T A + ALE G+ H DTA YG E
Sbjct: 4 VPEVALRHGAGRPMPAVG--VGTADSAATSPETK--RGAALAALEVGFRHFDTAALYGTE 59
Query: 260 DQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
+G A+ + GL RE +F+TTKLW + V+P+LR+SL NL +EYVDLYL+H
Sbjct: 60 APLGEAIAEATRRGLVASREEVFVTTKLWCTQCHPGLVLPSLRESLRNLQMEYVDLYLVH 119
Query: 434 WPIAMFENDTLL-----DNV--DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 592
WPI++ +L D V DF WR M + +LGL K+IG+SNF + + +++
Sbjct: 120 WPISVKPGPPMLPVKREDAVPFDFEGVWRAMEECHRLGLAKAIGVSNFTTKHLDKLLAVA 179
Query: 593 LEKPSALQIELN 628
P+ Q+E+N
Sbjct: 180 TIPPAVNQVEMN 191
>UniRef50_P27800 Cluster: Aldehyde reductase 1; n=18; root|Rep:
Aldehyde reductase 1 - Sporobolomyces salmonicolor
Length = 323
Score = 126 bits (304), Expect = 4e-28
Identities = 75/197 (38%), Positives = 109/197 (55%), Gaps = 15/197 (7%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
+V T L++G ++ +V GTW + Q V A+E GY H+D A Y
Sbjct: 1 MVGTTTLNTGASLELVGYGTWQA---------APGEVGQGVKVAIETGYRHLDLAKVYSN 51
Query: 257 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
+ +VG A+ + G+KRE +FIT+KLWN+ H EQV PAL +L+ L LEY+DLYLIHW
Sbjct: 52 QPEVGAAIKEA---GVKREDLFITSKLWNNSHRPEQVEPALDDTLKELGLEYLDLYLIHW 108
Query: 437 PIA----------MF----ENDTLLD-NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 571
P+A +F + + LD V +DTW+ M+ G K+IG+SNF+ + +
Sbjct: 109 PVAFPPEGDITQNLFPKANDKEVKLDLEVSLVDTWKAMVKLLDTGKVKAIGVSNFDAKMV 168
Query: 572 QRIIDSGLEKPSALQIE 622
II++ PS QIE
Sbjct: 169 DAIIEATGVTPSVNQIE 185
>UniRef50_Q96JD6-2 Cluster: Isoform 2 of Q96JD6 ; n=4;
Catarrhini|Rep: Isoform 2 of Q96JD6 - Homo sapiens
(Human)
Length = 263
Score = 94.7 bits (225), Expect(2) = 4e-28
Identities = 52/113 (46%), Positives = 68/113 (60%), Gaps = 1/113 (0%)
Frame = +2
Query: 107 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 286
G+IP V L +W GKV + AV A++AGY H D AY Y E +VG +
Sbjct: 2 GDIPAVGLSSWKAS--PGKVTE-------AVKEAIDAGYRHFDCAYFYHNEREVGAGIRC 52
Query: 287 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
K EG ++RE +FI TKLW + H++ V A RKSL+ L L Y+DLYLIHWP+
Sbjct: 53 KIKEGAVRREDLFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPM 105
Score = 52.8 bits (121), Expect(2) = 4e-28
Identities = 27/57 (47%), Positives = 36/57 (63%), Gaps = 2/57 (3%)
Frame = +2
Query: 455 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQI 619
N + + DFLDTW M D GL K+IG+SNFN EQ++R+++ GL KP QI
Sbjct: 139 NMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNKPGLRFKPLTNQI 195
>UniRef50_Q16K66 Cluster: Aldo-keto reductase; n=2; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 303
Score = 126 bits (303), Expect = 6e-28
Identities = 75/189 (39%), Positives = 113/189 (59%), Gaps = 8/189 (4%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
L L++G +IP + LGT+ K+ +D A+ A+E GY IDTA+ Y E V
Sbjct: 2 LALNNGHSIPPIGLGTY-------KITG--SDGVAAIKSAVEFGYRLIDTAFVYNNEQVV 52
Query: 269 GRALTKKFSEG--LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
G+AL + FS+G + RE +FI +KL ++H E V R SLE L L+YVDLYL+H P+
Sbjct: 53 GQALREIFSQGNDINREDVFIVSKLGPTFHRPEAVEKGCRLSLERLGLDYVDLYLMHTPV 112
Query: 443 AMFE----ND--TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 604
A + ND + D V L+TW+ + + ++ GL +SIG+SNFN+EQ+ I+ G +P
Sbjct: 113 AARDSGDGNDRSEIDDEVTPLETWKALEECQRKGLVRSIGVSNFNEEQLMEIVTHGSIRP 172
Query: 605 SALQIELNL 631
Q+E ++
Sbjct: 173 VVNQVECSI 181
>UniRef50_Q83N50 Cluster: 2,5-diketo-D-gluconic acid reductase; n=2;
Tropheryma whipplei|Rep: 2,5-diketo-D-gluconic acid
reductase - Tropheryma whipplei (strain Twist)
(Whipple's bacillus)
Length = 283
Score = 125 bits (302), Expect = 8e-28
Identities = 75/183 (40%), Positives = 104/183 (56%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VP++ L G +IP LGT+ P N+ V A+E GY HIDTA Y E
Sbjct: 9 VPSVLLGDGVSIPQFGLGTY--ELPP-------NEASSVVQSAIELGYRHIDTASLYANE 59
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+VGRA+ S G+KRE F+TTKLWNS + + A +SL+ L+L+YVDLYLIHWP
Sbjct: 60 REVGRAIA---SSGIKREEFFVTTKLWNSDQPKPR--EAFERSLDLLSLDYVDLYLIHWP 114
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
E +++ W +++ K+ G KS+G+SNF E I +I ++G PS QI
Sbjct: 115 CPPSEL--------YINVWEVLLELKESGRAKSVGVSNFLSEHIDKIKEAGFPLPSVNQI 166
Query: 620 ELN 628
EL+
Sbjct: 167 ELH 169
>UniRef50_Q7G764 Cluster: Probable NAD(P)H-dependent oxidoreductase
1; n=32; Eukaryota|Rep: Probable NAD(P)H-dependent
oxidoreductase 1 - Oryza sativa subsp. japonica (Rice)
Length = 321
Score = 125 bits (301), Expect = 1e-27
Identities = 58/161 (36%), Positives = 98/161 (60%), Gaps = 10/161 (6%)
Frame = +2
Query: 176 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSY 349
+ DT A++ A+E GY H DTA Y E VG A+ + GL R +F+T+K+W S
Sbjct: 31 SEDTTAAMLRAIELGYRHFDTARIYATEGCVGEAVAEAVRRGLIASRADVFVTSKIWCSD 90
Query: 350 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGM 505
+V+PA R++L NL ++YVDL L+HWP+++ F + +L + D WRGM
Sbjct: 91 LHAGRVVPAARETLRNLGMDYVDLLLVHWPVSLTPGNYDFPFPKEVILPSFDMEGVWRGM 150
Query: 506 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
+ +LGL ++IG+SNF+ +++++++ +P+ Q+E+N
Sbjct: 151 EECHRLGLARAIGVSNFSAKKLEQLLSLAAVRPAVNQVEVN 191
>UniRef50_A7SIT3 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 323
Score = 124 bits (300), Expect = 1e-27
Identities = 70/190 (36%), Positives = 114/190 (60%), Gaps = 11/190 (5%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
+L++G +IP +ALGTW + +V N AV A+E GY HID A YG E ++G
Sbjct: 9 KLNTGASIPAMALGTWQSSKE-----EVGN----AVRLAIELGYRHIDCAEIYGNEGEIG 59
Query: 272 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
AL++ +EG +KRE +F+T+KLW H + V+PA + +L+NL L+Y+DLYLIH P+A
Sbjct: 60 EALSEVLTEGKVKREELFVTSKLWCDSHHPDDVLPACQATLKNLQLDYLDLYLIHIPVAF 119
Query: 449 FENDTLLDNV----------DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 598
+ L ++ +TW+ M GL K+IG+SNF+ +++ +++++
Sbjct: 120 KKGVRLPHSIAEGIIGYTPEGVQNTWQAMEGLVAKGLCKAIGVSNFSVKRLNKLLETASI 179
Query: 599 KPSALQIELN 628
P+ Q+EL+
Sbjct: 180 VPACNQVELH 189
>UniRef50_A7BA05 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 292
Score = 124 bits (299), Expect = 2e-27
Identities = 72/182 (39%), Positives = 103/182 (56%), Gaps = 1/182 (0%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+PT L +G IPV+ GT+ KV DT AV ALE GY HIDTA YG E
Sbjct: 16 IPTFMLPTGSPIPVLGFGTY-------KVAP--EDTYDAVSRALEVGYRHIDTAQMYGNE 66
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+VG AL + G+ RE +FITTK+ NS HE ++ ++R+SLE+L +YVDL L+HWP
Sbjct: 67 AEVGAALE---ASGIAREDLFITTKVDNSNHEPDRAAASIRRSLEDLRTDYVDLLLVHWP 123
Query: 440 I-AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
+ ++ D L W + DA G ++IG+SN+ +E ++ + + P LQ
Sbjct: 124 LPTLYGGDVAL-------PWPALEDAFNAGGARAIGLSNYEREHVEAVREVATVAPHVLQ 176
Query: 617 IE 622
+E
Sbjct: 177 VE 178
>UniRef50_P06632 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=8; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase A - Corynebacterium sp. (strain ATCC 31090)
Length = 278
Score = 124 bits (299), Expect = 2e-27
Identities = 72/185 (38%), Positives = 107/185 (57%)
Frame = +2
Query: 74 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 253
+ VP++ L+ G +IP + G + KV DT++AV ALE GY HIDTA YG
Sbjct: 1 MTVPSIVLNDGNSIPQLGYGVF-------KVPPA--DTQRAVEEALEVGYRHIDTAAIYG 51
Query: 254 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
E+ VG A+ + G+ R+ +FITTKLWN H+ ++ A+ +SL L L+ VDLYL+H
Sbjct: 52 NEEGVGAAIA---ASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVH 108
Query: 434 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 613
WP +N ++ W MI+ + GLT+SIG+SN ++RI+ + P+
Sbjct: 109 WPTPAADN--------YVHAWEKMIELRAAGLTRSIGVSNHLVPHLERIVAATGVVPAVN 160
Query: 614 QIELN 628
QIEL+
Sbjct: 161 QIELH 165
>UniRef50_Q55FL3 Cluster: Aldo-keto reductase; n=2; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 321
Score = 124 bits (298), Expect = 2e-27
Identities = 76/196 (38%), Positives = 108/196 (55%), Gaps = 17/196 (8%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
+L+ G IP + LGT+ P G+V N+ AL+ GY HID A YG E +G
Sbjct: 18 KLNDGNQIPSIGLGTYYSENP-GEVGDAINN-------ALKNGYRHIDGAAFYGNEKVIG 69
Query: 272 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
+L + F EG +KRE IF T+KLWNS H V+ K++E+L + Y+DLYLIHWPIA
Sbjct: 70 NSLKEIFKEGEIKREDIFYTSKLWNSCHNSNLVVKHCVKTIEDLGIGYLDLYLIHWPIA- 128
Query: 449 FEN----------------DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 580
FEN + ++ V +TW+ M +LGL KSIG+SNFN + + +
Sbjct: 129 FENSNPLGLTIEPLRDQNGNPIIAPVSIRETWQEMEKLVELGLVKSIGVSNFNVQNLVDL 188
Query: 581 IDSGLEKPSALQIELN 628
+ KP Q+E++
Sbjct: 189 LTYAKIKPVVNQVEIH 204
>UniRef50_A1UEC5 Cluster: 2,5-didehydrogluconate reductase; n=20;
Corynebacterineae|Rep: 2,5-didehydrogluconate reductase
- Mycobacterium sp. (strain KMS)
Length = 283
Score = 123 bits (297), Expect = 3e-27
Identities = 75/183 (40%), Positives = 107/183 (58%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+P++ L+ G +IPV+ LG G++ + + E++V ALEAGY IDTA YG E
Sbjct: 11 IPSVSLNDGHSIPVLGLGV-------GELSEA--EAERSVAAALEAGYRLIDTAAVYGNE 61
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
VGRA+ + G+ RE I++TTKL + A R SLE L L+YVDLYLIHWP
Sbjct: 62 AAVGRAVN---ASGIPREEIYVTTKLAVADQGFGTSQDAARASLERLGLDYVDLYLIHWP 118
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
D+ ++D+W G++ AK+ G+ +SIG+ NFN E + IID P+ QI
Sbjct: 119 AG--------DHGKYIDSWGGLMKAKQDGVARSIGVCNFNAEHLSNIIDLSFFTPAINQI 170
Query: 620 ELN 628
EL+
Sbjct: 171 ELH 173
>UniRef50_Q1YPE5 Cluster: Aldehyde reductase; n=7; Bacteria|Rep:
Aldehyde reductase - gamma proteobacterium HTCC2207
Length = 330
Score = 122 bits (294), Expect = 7e-27
Identities = 74/201 (36%), Positives = 112/201 (55%), Gaps = 20/201 (9%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VP +++SS ++P V LG W K+ Q + QAV A++ GY H+D+A YG E
Sbjct: 7 VPGVKVSSK-SMPAVGLGLW-------KITQ--DSAAQAVYEAIKVGYRHLDSAADYGNE 56
Query: 260 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
QVG + + +EGL RE ++ITTKLWN+YH E V A R+S+++L L+Y+DLYL+H+
Sbjct: 57 QQVGEGIARAIAEGLCSREELWITTKLWNTYHRAEHVEAACRRSMDDLGLDYIDLYLVHF 116
Query: 437 PIAM--------------FENDT-----LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFN 559
PIA+ F++ LD V +TW M + GL + IG+ N++
Sbjct: 117 PIALRYVDFNDRYPAEWIFDHSAEDPAMELDQVPLSETWGAMEQLVESGLVRQIGVCNYS 176
Query: 560 QEQIQRIIDSGLEKPSALQIE 622
+ ++ KP+ LQIE
Sbjct: 177 AVLLHDLMSYARIKPAMLQIE 197
>UniRef50_Q0IBY6 Cluster: Alcohol dehydrogenase; n=2;
Chroococcales|Rep: Alcohol dehydrogenase - Synechococcus
sp. (strain CC9311)
Length = 336
Score = 122 bits (294), Expect = 7e-27
Identities = 69/195 (35%), Positives = 112/195 (57%), Gaps = 13/195 (6%)
Frame = +2
Query: 77 IVPTLQ---LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 247
++PT+Q LS+G +P++ LGT K + QV +A+ + GY HID A
Sbjct: 15 VIPTMQYASLSNGDRMPLLGLGTG-----KSESRQVYKSVREAI----KIGYRHIDCASI 65
Query: 248 YGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 424
YG E++VG A+ + + R ++IT+KLW++ H + V AL +SL+NL ++Y++LY
Sbjct: 66 YGNEEEVGDAIRDAIQNHEITRSELWITSKLWSNCHGKNHVEAALSQSLQNLGVDYLNLY 125
Query: 425 LIHWPIAMFENDTLLDNVDFL---------DTWRGMIDAKKLGLTKSIGISNFNQEQIQR 577
LIHWP+ + T ++VD L +TW M + GLTK IG+SNF +++Q+
Sbjct: 126 LIHWPVGIRPEKTFAESVDDLLTPEESPISETWEAMESTRDKGLTKHIGVSNFTVKKLQQ 185
Query: 578 IIDSGLEKPSALQIE 622
++ +KP Q+E
Sbjct: 186 LVSHCKQKPEVNQVE 200
>UniRef50_P14065 Cluster: Protein GCY; n=13; Saccharomycetales|Rep:
Protein GCY - Saccharomyces cerevisiae (Baker's yeast)
Length = 312
Score = 122 bits (294), Expect = 7e-27
Identities = 78/200 (39%), Positives = 112/200 (56%), Gaps = 20/200 (10%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
L L++G IP + LGTW ND +AV+ AL+ GY HIDTA Y EDQV
Sbjct: 12 LSLNTGAQIPQIGLGTWQSKE---------NDAYKAVLTALKDGYRHIDTAAIYRNEDQV 62
Query: 269 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI-- 442
G+A+ G+ RE IF+TTKLW + H +V AL +SL+ L L+YVDLYL+HWP
Sbjct: 63 GQAIK---DSGVPREEIFVTTKLWCTQHHEPEV--ALDQSLKRLGLDYVDLYLMHWPARL 117
Query: 443 --AMFENDTLLD--------------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 574
A +N+ +L N +F+ TW M + K G TK++G+SNF+ ++
Sbjct: 118 DPAYIKNEDILSVPTKKDGSRAVDITNWNFIKTWELMQELPKTGKTKAVGVSNFSINNLK 177
Query: 575 RIIDSGLEK--PSALQIELN 628
++ S K P+A Q+E++
Sbjct: 178 DLLASQGNKLTPAANQVEIH 197
>UniRef50_Q9U2J5 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 339
Score = 121 bits (292), Expect = 1e-26
Identities = 66/200 (33%), Positives = 109/200 (54%), Gaps = 16/200 (8%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
I T+ L+SG +PV+ GTW PK + D ALEAGY HID+A +
Sbjct: 3 IADTVTLNSGYEMPVIGYGTW--QLPKNLAAERVRD-------ALEAGYRHIDSALSFKN 53
Query: 257 EDQVGRALTKKFS-EGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
+++V + ++RE +F+++K+WN+YH R + + + + LE Y+DL +IH
Sbjct: 54 QEEVAAGIKDWCKIRKVRREELFLSSKIWNTYHSRNRCMQQIDEMLEIFETTYMDLIVIH 113
Query: 434 WPIAMFEND---------------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQ 568
WP E++ +VD+L+TW+ + DA + G +SIG++NFN Q
Sbjct: 114 WPFGWAEDEPPGERGLWPRGANGKMRYSDVDYLETWKALEDAHRSGKIRSIGLANFNIGQ 173
Query: 569 IQRIIDSGLEKPSALQIELN 628
++++ GL KP+ LQ+E+N
Sbjct: 174 VEQVWTKGLIKPAVLQVEMN 193
>UniRef50_Q6CFG7 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=9; Ascomycota|Rep:
Yarrowia lipolytica chromosome B of strain CLIB122 of
Yarrowia lipolytica - Yarrowia lipolytica (Candida
lipolytica)
Length = 337
Score = 121 bits (291), Expect = 2e-26
Identities = 74/191 (38%), Positives = 104/191 (54%), Gaps = 13/191 (6%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L++G IP + LGTW K +V E A+ E GY HIDTA+ Y ED VG
Sbjct: 36 LNNGKTIPAIGLGTW-----KSTTEEVAGAVECALT---EGGYRHIDTAFNYRNEDAVGL 87
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 454
+ + +G+KRE IF+TTK+W +YH+R V L SLE L L+YVD+ LIHWP+ +
Sbjct: 88 GIKRAMEKGVKREDIFVTTKIWVTYHDR--VEENLDMSLERLGLDYVDMLLIHWPVPLNP 145
Query: 455 N--DTLL----DNVDFLD-------TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 595
N D + D +D TW+ M K G TKSIG+SNF+ ++ ++
Sbjct: 146 NGNDPVYPLRPDGSRDIDESGSQPKTWKQMEAVLKTGKTKSIGVSNFSIPYLEELLKEAE 205
Query: 596 EKPSALQIELN 628
P+ Q+EL+
Sbjct: 206 VVPAVNQVELH 216
>UniRef50_A2QBD7 Cluster: Catalytic activity: an alcohol + NADP(+)
<=> an aldehyde + NADPH; n=4; Trichocomaceae|Rep:
Catalytic activity: an alcohol + NADP(+) <=> an aldehyde
+ NADPH - Aspergillus niger
Length = 323
Score = 121 bits (291), Expect = 2e-26
Identities = 72/186 (38%), Positives = 103/186 (55%), Gaps = 10/186 (5%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
+++G IP V GTW + K ++V N AV AL GY HID A Y E +VG
Sbjct: 9 INTGAKIPAVGFGTW-----QAKPLEVEN----AVEVALREGYRHIDCAAIYRNETEVGN 59
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-- 448
+ K G+ RE IFIT KLWN+ H E V PAL K+L++L + Y+DLYL+HWP A
Sbjct: 60 GIRKS---GVPREEIFITGKLWNTKHAPEDVEPALDKTLQDLGVAYLDLYLMHWPCAFKG 116
Query: 449 ------FENDTLLD--NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 604
+D + D N+D++ T+R M G ++IG+SNFN +++ ++ P
Sbjct: 117 GDKWFPLNDDGVFDLANIDYITTYRAMEKLLATGKVRAIGVSNFNIRRLEELLGQVSVVP 176
Query: 605 SALQIE 622
+ QIE
Sbjct: 177 AVNQIE 182
>UniRef50_Q7ZWA4 Cluster: Zgc:56622; n=6; cellular organisms|Rep:
Zgc:56622 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 120 bits (289), Expect = 3e-26
Identities = 62/158 (39%), Positives = 93/158 (58%), Gaps = 11/158 (6%)
Frame = +2
Query: 188 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQ 364
++A A+ AGY HIDTA+ Y E VG A+ K +G+ +R+ +FI +KLW ++H E
Sbjct: 3 QRACEAAIAAGYRHIDTAFCYRNEVDVGMAIQNKIQQGIIRRQDMFIVSKLWGTHHAPED 62
Query: 365 VIPALRKSLENLNLEYVDLYLIHWPIAMF--------END--TLLDNVDFLDTWRGMIDA 514
+ KSL +L L+Y+D YL+H+P+ + E D L ++D++D WRGM
Sbjct: 63 IPVCFNKSLSDLQLDYLDQYLVHFPVGLKKVGDELFPERDGKILTTDIDYVDVWRGMEAL 122
Query: 515 KKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
K G KSIG+SNF EQI R++ P+ Q+EL+
Sbjct: 123 KATGKVKSIGVSNFTMEQIDRLLSVAKIPPAVNQVELH 160
>UniRef50_Q7WSY4 Cluster: Putative aldo-keto reductase; n=1;
Propionibacterium freudenreichii subsp. shermanii|Rep:
Putative aldo-keto reductase - Propionibacterium
freudenreichii subsp. shermanii
Length = 280
Score = 120 bits (289), Expect = 3e-26
Identities = 70/182 (38%), Positives = 104/182 (57%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
PT++LS G +P++ +GTW KG+ + AV A+E GY +DTA YG E+
Sbjct: 9 PTVELSGGTRMPMLGMGTW---PLKGE------ECRAAVASAIEQGYRLVDTAEAYGNEE 59
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VG+A+ + G R IF+TTK +H R+ V AL SLE L L+YVDL+L+HWP+
Sbjct: 60 AVGKAVREA---GPDRAEIFVTTKFSKQWHSRKGVHEALEHSLERLGLDYVDLFLMHWPM 116
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
++D +RGM++ K+ GL K+IG+SNF + +I G+ P QI+
Sbjct: 117 P--------GEGSYVDAYRGMVELKEQGLAKAIGVSNFKVHHLDDLITEGM-TPEVNQIQ 167
Query: 623 LN 628
L+
Sbjct: 168 LD 169
>UniRef50_Q1U9L6 Cluster: 2,5-didehydrogluconate reductase; n=3;
Lactobacillus|Rep: 2,5-didehydrogluconate reductase -
Lactobacillus reuteri 100-23
Length = 288
Score = 120 bits (288), Expect = 4e-26
Identities = 71/183 (38%), Positives = 101/183 (55%), Gaps = 2/183 (1%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T L++G IP V GT+ R V EQAV A+E GY HIDTA YG E+
Sbjct: 10 TFNLNNGVKIPCVGYGTF---RTPADVA------EQAVKEAIETGYRHIDTAAVYGNEEA 60
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI- 442
VG+ + G+KRE +F+T+KLWN+ EQ A +++L+ L ++Y+DLYLIHWP
Sbjct: 61 VGKGIK---DSGIKREDLFVTSKLWNTNRGYEQTKKAFQETLDRLQMDYLDLYLIHWPAN 117
Query: 443 -AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
F +D N +TWR M D G ++IG+SNF I ++ + P+ QI
Sbjct: 118 EKQFGDDAAKINA---ETWRAMEDLYNEGKIRAIGVSNFMPHHIAELMKTAKVAPAVDQI 174
Query: 620 ELN 628
E++
Sbjct: 175 EVH 177
>UniRef50_A6RKL9 Cluster: Putative uncharacterized protein; n=3;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 360
Score = 119 bits (287), Expect = 5e-26
Identities = 71/173 (41%), Positives = 99/173 (57%), Gaps = 2/173 (1%)
Frame = +2
Query: 116 PVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFS 295
P++ GTW V N TE AV YA+E GY ID A YG E VGR + +
Sbjct: 40 PLIGFGTW------NLKVSPENTTE-AVAYAIEIGYRQIDCAAVYGNEVAVGRGIEEGLK 92
Query: 296 E-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 469
GLKRE I++T+KLWN +H E V L ++L++L LEY+DLYLIHWPI N
Sbjct: 93 RAGLKREDIWVTSKLWNDHHGSYENVEKGLNQTLQDLGLEYLDLYLIHWPIGFSSNGA-- 150
Query: 470 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
N+D + T++ MI K +IG+SNF+ Q++ ++ +G P Q+EL+
Sbjct: 151 KNLDHVQTYKSMISLPK-SRVLNIGVSNFSPLQLKNVVSTG-TIPYMHQMELH 201
>UniRef50_UPI0000498F1F Cluster: oxidoreductase, aldo/keto reductase
family; n=2; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 305
Score = 119 bits (286), Expect = 7e-26
Identities = 65/182 (35%), Positives = 105/182 (57%), Gaps = 3/182 (1%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L++G IP + LGTW+ + +AV A++ GY HID A YG E +VG
Sbjct: 7 LNNGYKIPKLGLGTWMS---------ANGEVGKAVEIAIKNGYRHIDCAKAYGNEKEVGD 57
Query: 275 ALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 451
+ ++G +KRE +F+TTKLW++ +E V PA +SL+ L LEY+DLY+IH P+
Sbjct: 58 GIKSAIAKGYVKREELFVTTKLWSTDKHKEDVRPACLESLKKLQLEYLDLYIIHIPLTAD 117
Query: 452 E--NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 625
+ + + + +TWR M + GL KSIG+SNFN ++++ ++ +P+ Q E
Sbjct: 118 KKTGEFTEEIIPIEETWREMEKLVEEGLVKSIGVSNFNIKKLEELLAIAKIQPAVNQFEF 177
Query: 626 NL 631
++
Sbjct: 178 HI 179
>UniRef50_A5KSS3 Cluster: Aldehyde reductase; n=1; candidate
division TM7 genomosp. GTL1|Rep: Aldehyde reductase -
candidate division TM7 genomosp. GTL1
Length = 299
Score = 119 bits (286), Expect = 7e-26
Identities = 70/191 (36%), Positives = 105/191 (54%), Gaps = 11/191 (5%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
L L + +P++ GTW P G T V A++AGY HID A YG E +V
Sbjct: 4 LTLRNKQTLPLLGYGTW--ELPTGT-------TADLVETAIKAGYRHIDCAMIYGNEKEV 54
Query: 269 GRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
G + + +G+ KRE +F+T+KLWN+ H + V A RK+L +L L+Y+DLYLIHW +A
Sbjct: 55 GEGIRRTIDQGVVKREDLFVTSKLWNTDHAQVDVGVACRKTLNDLGLDYLDLYLIHWGVA 114
Query: 446 MFENDTL--LDN--------VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 595
D L LD+ + +TW+ M + + GL KS+G++NF + ++
Sbjct: 115 FEHGDNLEPLDDDGVAKFSFISMKETWQAMEELVEQGLVKSMGVANFTAPMLLDLLSYAK 174
Query: 596 EKPSALQIELN 628
KP+ QIEL+
Sbjct: 175 IKPAVHQIELH 185
>UniRef50_Q5KI95 Cluster: Aldo-keto reductase, putative; n=14;
Dikarya|Rep: Aldo-keto reductase, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 353
Score = 119 bits (286), Expect = 7e-26
Identities = 79/204 (38%), Positives = 112/204 (54%), Gaps = 14/204 (6%)
Frame = +2
Query: 59 FTSAELIVPT-LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHID 235
F S + PT +L++G +IP + LGTW + K +V QAV +AL+AGY HID
Sbjct: 28 FNSLIMSAPTSFKLNTGASIPAIGLGTW-----QAKAGEV----RQAVAHALKAGYRHID 78
Query: 236 TAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 415
A Y ED+VG + G+ R IF+T+K+W+SYH+R V L +L++L +Y+
Sbjct: 79 GALCYQNEDEVGLGIK---DSGVPRSEIFLTSKVWSSYHDR--VEECLDTTLKSLQTDYL 133
Query: 416 DLYLIHWPIAMFENDT------------LLD-NVDFLDTWRGMIDAKKLGLTKSIGISNF 556
DLYLIHWP+ + N T LD + D TW M D K G K+IG+SN
Sbjct: 134 DLYLIHWPVRLAPNGTHPLFPVKPDGSRNLDWDWDQAKTWAQMEDVLKKGKAKAIGLSNA 193
Query: 557 NQEQIQRIIDSGLEKPSALQIELN 628
I+ II +G P+ Q+EL+
Sbjct: 194 GIPIIEHIIKTGKVTPAVNQVELH 217
>UniRef50_Q7G765 Cluster: Probable NAD(P)H-dependent oxidoreductase
2; n=6; Magnoliophyta|Rep: Probable NAD(P)H-dependent
oxidoreductase 2 - Oryza sativa subsp. japonica (Rice)
Length = 322
Score = 119 bits (286), Expect = 7e-26
Identities = 57/161 (35%), Positives = 95/161 (59%), Gaps = 10/161 (6%)
Frame = +2
Query: 176 TNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSY 349
+ +T A++ A+E GY H DTA Y E V A+ + GL R +F+T+KLW S
Sbjct: 33 SEETTAALLRAIELGYRHFDTARLYATEGCVSEAVAEAVRRGLVASRADVFVTSKLWCSD 92
Query: 350 HEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--------FENDTLLDNVDFLDTWRGM 505
+V+PA R++L NL ++YVDL L+HWP + F + + D WRGM
Sbjct: 93 LHAGRVVPAARETLRNLGMDYVDLLLVHWPATVAPGSYDFPFPKEEMAPAFDMEGVWRGM 152
Query: 506 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
+ +LGL ++IG+SNF+ +++++++ + +P+A Q+E+N
Sbjct: 153 EECHRLGLARAIGVSNFSAKKLEQLLSFAVVRPAANQVEMN 193
>UniRef50_A2EHN6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=10; Trichomonas vaginalis|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 312
Score = 118 bits (284), Expect = 1e-25
Identities = 72/189 (38%), Positives = 112/189 (59%), Gaps = 16/189 (8%)
Frame = +2
Query: 113 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALE-AGYTHIDTAYKYGIEDQVGRALTKK 289
IP + GT+L + P + A+ YA+E G HIDTA+ Y ++ +G L +
Sbjct: 3 IPQLGFGTYLANDPA--------KLKAALHYAIEECGVRHIDTAFAYYNQNVIGETLKEI 54
Query: 290 FSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM----FE 454
F++G +KRE +FITTKLW ++H ++ V P L ++L L L YVDL+LIH PIA +
Sbjct: 55 FAKGKIKREDMFITTKLWCTHHRKDLVEPELHENLAQLQLSYVDLFLIHQPIAFKSLPAK 114
Query: 455 NDTLL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 604
+ T++ + +D L+T+ M + +K GLT+ IG+SNF+ EQ++RI + KP
Sbjct: 115 DGTMMPKDEKGKIQYEQIDILETYHAMEECQKKGLTRHIGVSNFSIEQLERIWFNCEIKP 174
Query: 605 SALQIELNL 631
A Q+E N+
Sbjct: 175 YANQVECNI 183
>UniRef50_P23901 Cluster: Aldose reductase; n=9; Poaceae|Rep: Aldose
reductase - Hordeum vulgare (Barley)
Length = 320
Score = 118 bits (284), Expect = 1e-25
Identities = 64/185 (34%), Positives = 103/185 (55%), Gaps = 7/185 (3%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKYGIEDQVG 271
L SG +P V LGTW + +DT +V A+ EAGY H+DTA +YG+E +VG
Sbjct: 18 LKSGHAMPAVGLGTW----------RAGSDTAHSVRTAITEAGYRHVDTAAEYGVEKEVG 67
Query: 272 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 451
+ L G+ R+ +F+T+K+W + E+V PAL +L++L L+Y+DLY IHWP +
Sbjct: 68 KGLKAAMEAGIDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK 127
Query: 452 ENDTL------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 613
+ + + D W+ M + K GL K IG+ N+ ++ R++ S P+
Sbjct: 128 DGAHMPPEAGEVLEFDMEGVWKEMENLVKDGLVKDIGVCNYTVTKLNRLLRSAKIPPAVC 187
Query: 614 QIELN 628
Q+E++
Sbjct: 188 QMEMH 192
>UniRef50_A3C1Z7 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa (japonica cultivar-group)|Rep: Putative
uncharacterized protein - Oryza sativa subsp. japonica
(Rice)
Length = 288
Score = 118 bits (283), Expect = 2e-25
Identities = 68/195 (34%), Positives = 113/195 (57%), Gaps = 12/195 (6%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+P LSSG +P V +GT P G T + V+ A+EAGY H DTA Y E
Sbjct: 1 MPEAALSSGKPMPRVGMGT--ASFPLGATDPST--VKDVVLRAIEAGYRHFDTAAVYQTE 56
Query: 260 DQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
+G A+ + GL R+ ++IT+KLW ++ V+P+LR++L + +EY+DLYLIH
Sbjct: 57 AILGDAVAEAVRAGLVASRDELYITSKLWVAHAHPGHVLPSLRRALRKMQMEYLDLYLIH 116
Query: 434 WPIAM----------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 583
+P++M + D L+ +D W+ M + ++LGLTK+IG+SNF+ ++++ ++
Sbjct: 117 FPVSMRLAEDPESMTYSKDDLV-MMDMEGVWKEMEECQRLGLTKAIGVSNFSCKKLETLL 175
Query: 584 DSGLEKPSALQIELN 628
P+A Q+E++
Sbjct: 176 SFATISPAANQVEVH 190
>UniRef50_P51857 Cluster: 3-oxo-5-beta-steroid 4-dehydrogenase (EC
1.3.1.3) (Delta(4)-3- ketosteroid 5-beta-reductase);
n=124; cellular organisms|Rep: 3-oxo-5-beta-steroid
4-dehydrogenase (EC 1.3.1.3) (Delta(4)-3- ketosteroid
5-beta-reductase) - Homo sapiens (Human)
Length = 326
Score = 118 bits (283), Expect = 2e-25
Identities = 74/191 (38%), Positives = 108/191 (56%), Gaps = 13/191 (6%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
+ LS G +IP++ LGT+ + K T+ V A++ GY HID AY Y E +V
Sbjct: 10 IPLSDGNSIPIIGLGTYSEPKSTPKGACATS-----VKVAIDTGYRHIDGAYIYQNEHEV 64
Query: 269 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
G A+ +K +EG ++RE IF KLW + H E V P L ++L L L+YVDLY+I P+A
Sbjct: 65 GEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMA 124
Query: 446 MFENDTLL---DNVDFL-------DTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-G 592
D + +N +L TW M K GL KS+G+SNFN+ Q++ I++ G
Sbjct: 125 FKPGDEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPG 184
Query: 593 LE-KPSALQIE 622
L+ KP + Q+E
Sbjct: 185 LKHKPVSNQVE 195
>UniRef50_Q01HB5 Cluster: OSIGBa0136O08-OSIGBa0153H12.9 protein;
n=4; Oryza sativa|Rep: OSIGBa0136O08-OSIGBa0153H12.9
protein - Oryza sativa (Rice)
Length = 337
Score = 117 bits (282), Expect = 2e-25
Identities = 71/202 (35%), Positives = 106/202 (52%), Gaps = 13/202 (6%)
Frame = +2
Query: 65 SAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 244
+A VP + L+SG +PV+ GT P D + +A+ GY H+DTA
Sbjct: 15 AAATAVPCVTLNSGHAMPVLGFGTGSSTPPA--------DLAATIAHAVRLGYRHLDTAA 66
Query: 245 KYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVD 418
YG E VG A+ + G R +F+TTKL + +V+ ALR+SL L L+YVD
Sbjct: 67 VYGTEGAVGAAVAEAVRCGAVASRGELFVTTKLSMADAHPPRVVAALRESLSRLGLDYVD 126
Query: 419 LYLIHWPIAMFENDTL-----------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQE 565
L+LIHWP+A+ + D L D WRGM + +LGL +SIG+SNF+
Sbjct: 127 LFLIHWPVAIGKKDAAGELTWDDLSRGLVPFDMEGVWRGMEECHRLGLARSIGVSNFSAA 186
Query: 566 QIQRIIDSGLEKPSALQIELNL 631
++ R++ P+ Q+E+N+
Sbjct: 187 KMSRLLALAAVPPAVNQVEMNV 208
>UniRef50_Q7QVQ9 Cluster: GLP_302_44328_45269; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_302_44328_45269 - Giardia lamblia
ATCC 50803
Length = 313
Score = 117 bits (281), Expect = 3e-25
Identities = 63/162 (38%), Positives = 91/162 (56%), Gaps = 15/162 (9%)
Frame = +2
Query: 188 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF---SEGLKRESIFITTKLWNSYHER 358
+ AV AL GY HID AY Y E+ +GRA K F S G+KRE ++IT+KLWN H
Sbjct: 20 QTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIKREDVWITSKLWNYNHRP 79
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND------------TLLDNVDFLDTWRG 502
E V +K++ +L ++Y+DL+L+HWP+A ND +L+ V DTWR
Sbjct: 80 ELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFPKDAEGRAMLEKVPLADTWRA 139
Query: 503 MIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
M + GL K IG+SN+ + +++ KP QIE++
Sbjct: 140 MEQLVEEGLVKHIGVSNYTVPLLADLLNYAKIKPLVNQIEIH 181
>UniRef50_A2FPE2 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=3; Trichomonas vaginalis G3|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Trichomonas vaginalis G3
Length = 309
Score = 117 bits (281), Expect = 3e-25
Identities = 67/188 (35%), Positives = 112/188 (59%), Gaps = 15/188 (7%)
Frame = +2
Query: 113 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 292
IP + LGT+L P V + E ++GY H+D A Y ++ +G AL++ F
Sbjct: 4 IPSIGLGTFLAEDPAALKAAVHSAIE-------DSGYRHVDCAAYYKNQEIIGEALSEIF 56
Query: 293 SEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM--FENDT 463
++G +KRE ++IT+K+WN+ H + ++ ++K+L+ L LEY+DL L+HW A E+D
Sbjct: 57 AKGQVKREEVWITSKVWNTKHRPDLLVKDVKKTLKELKLEYLDLVLVHWACAFQSREDDE 116
Query: 464 LL----------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGLE-KPS 607
L +N+D L+TW+ M + LGL K IG+SNF+ EQ++R+ D G++ +P
Sbjct: 117 YLPRDETGKIITENIDILETWKAMEECYNLGLAKHIGVSNFSIEQLERMRYDPGVKIQPY 176
Query: 608 ALQIELNL 631
Q+E ++
Sbjct: 177 CNQVESHM 184
>UniRef50_Q10494 Cluster: Probable oxidoreductase C26F1.07; n=2;
Schizosaccharomyces pombe|Rep: Probable oxidoreductase
C26F1.07 - Schizosaccharomyces pombe (Fission yeast)
Length = 321
Score = 117 bits (281), Expect = 3e-25
Identities = 69/188 (36%), Positives = 102/188 (54%), Gaps = 10/188 (5%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L+ G IP + LGTW N T+ AV AL+ GY HID A YG ED+VG
Sbjct: 18 LADGSKIPGLGLGTWRSE---------PNQTKNAVKTALQYGYRHIDAAAIYGNEDEVGD 68
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM-- 448
+ + G+ R+ I++T+KLW + H E V AL K+L++L L+Y+D YLIHWP++
Sbjct: 69 GIKES---GVPRKDIWVTSKLWCNAHAPEAVPKALEKTLKDLKLDYLDEYLIHWPVSFKT 125
Query: 449 ----FEND----TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 604
F D + + +TW+ M + G + IG+SNFN ++RI+ KP
Sbjct: 126 GEDKFPKDKDGNLIYEKNPIEETWKAMEKLLETGKVRHIGLSNFNDTNLERILKVAKVKP 185
Query: 605 SALQIELN 628
+ Q+EL+
Sbjct: 186 AVHQMELH 193
>UniRef50_A4RQH8 Cluster: Predicted protein; n=2; Ostreococcus|Rep:
Predicted protein - Ostreococcus lucimarinus CCE9901
Length = 337
Score = 116 bits (279), Expect = 5e-25
Identities = 70/180 (38%), Positives = 94/180 (52%), Gaps = 5/180 (2%)
Frame = +2
Query: 98 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 277
++G IP V LGTW RP N+ AV AL AGY H+D A Y E +VG A
Sbjct: 11 ANGLRIPRVGLGTWKA-RP--------NEVRDAVRDALGAGYAHVDCAAAYANESEVGEA 61
Query: 278 LTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 454
L + F G KRE +F+T+KLWN V AL +L +L + Y+DLYLIHWP+A
Sbjct: 62 LREAFERGDAKREDVFVTSKLWNDRRRPRDVREALMTTLNDLGVGYLDLYLIHWPVAWKR 121
Query: 455 NDTLLDNVD--FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK--PSALQIE 622
L + + + W + GL + IG+SNFN+ Q+ + D K P+ QIE
Sbjct: 122 GTVLQPDAEASIAECWSELERCVADGLVRHIGVSNFNEAQLAALCDDPRTKIQPACNQIE 181
>UniRef50_Q2V420 Cluster: Uncharacterized protein At2g37770.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At2g37770.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 283
Score = 116 bits (278), Expect = 6e-25
Identities = 69/184 (37%), Positives = 103/184 (55%), Gaps = 7/184 (3%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 272 RALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
L K F + + KRE +FIT+KLW + H+ + V AL ++L++L LEYVDLYLIHWP +
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 449 ------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 610
+ + LL VD TW+ M G ++IG+SNF+ +++ +++ P+
Sbjct: 120 KKGSVGIKPENLLP-VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAV 178
Query: 611 LQIE 622
Q+E
Sbjct: 179 NQVE 182
>UniRef50_Q0PGJ6 Cluster: Aldo-keto reductase; n=32;
Magnoliophyta|Rep: Aldo-keto reductase - Arabidopsis
thaliana (Mouse-ear cress)
Length = 315
Score = 116 bits (278), Expect = 6e-25
Identities = 69/184 (37%), Positives = 103/184 (55%), Gaps = 7/184 (3%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
+L++G P V LGTW G V AV A++ GY HID A YG E ++G
Sbjct: 9 KLNTGAKFPSVGLGTW--QASPGLV-------GDAVAAAVKIGYRHIDCAQIYGNEKEIG 59
Query: 272 RALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
L K F + + KRE +FIT+KLW + H+ + V AL ++L++L LEYVDLYLIHWP +
Sbjct: 60 AVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPARI 119
Query: 449 ------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 610
+ + LL VD TW+ M G ++IG+SNF+ +++ +++ P+
Sbjct: 120 KKGSVGIKPENLLP-VDIPSTWKAMEALYDSGKARAIGVSNFSTKKLADLLELARVPPAV 178
Query: 611 LQIE 622
Q+E
Sbjct: 179 NQVE 182
>UniRef50_Q4PAT5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 700
Score = 116 bits (278), Expect = 6e-25
Identities = 69/195 (35%), Positives = 106/195 (54%), Gaps = 16/195 (8%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L++G IP + GTW K Q T AV +A++ GY HID A+ Y ED V
Sbjct: 14 LANGAQIPKLGFGTW-----KMSKEQAT----PAVAHAIKTGYRHIDCAWAYRNEDAVAA 64
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 454
+ K G+ R +++T+KLWNS+H E V AL SL++L +Y+DLYL+HWP+A
Sbjct: 65 GIKKA---GVPRSQLWLTSKLWNSFHHPEHVEKALDASLKDLGTDYLDLYLMHWPVAFLN 121
Query: 455 N-DTLLDNV---------------DFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
+ +++ ++ DF+ T+R M + K G ++IG+SNFN + ++D
Sbjct: 122 SKGSMVPSIRSTGGHPVESEDLSRDFMATYRVMEEMVKKGKVRNIGVSNFNIRRTSEVVD 181
Query: 587 SGLEKPSALQIELNL 631
KP Q+E+NL
Sbjct: 182 EASIKPVVNQVEVNL 196
>UniRef50_P22045 Cluster: Probable reductase; n=101; cellular
organisms|Rep: Probable reductase - Leishmania major
Length = 284
Score = 115 bits (276), Expect = 1e-24
Identities = 67/178 (37%), Positives = 97/178 (54%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
LS+G +P LG W P G+V TE AV +AL AGY HIDTA Y E+ VG
Sbjct: 11 LSNGVKMPQFGLGVW--QSPAGEV------TENAVNWALCAGYRHIDTAAIYKNEESVGA 62
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 454
L + G+ RE +FITTKLWN+ E + A +S + L ++Y+DLYLIHWP +
Sbjct: 63 GLR---ASGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG--K 117
Query: 455 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
+ + +LD+WR K ++IG+SNF+ ++ ++ P Q+EL+
Sbjct: 118 DILSKEGKKYLDSWRAFEQLYKEKKVRAIGVSNFHIHHLEDVLAMCTVTPMVNQVELH 175
>UniRef50_Q8ZI40 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=74; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Yersinia pestis
Length = 277
Score = 115 bits (276), Expect = 1e-24
Identities = 73/182 (40%), Positives = 99/182 (54%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P ++L G +P + LG W +TE AV ALE GY IDTA Y E+
Sbjct: 5 PLIKLYDGRLMPQLGLGVWQAS---------IQETELAVSKALEVGYRSIDTAAIYKNEE 55
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VG+AL + + R+ +FITTKLWN Q AL SL+ L L+YVDLYLIHWP
Sbjct: 56 GVGKALK---AAAVARDELFITTKLWNDDQHNPQ--QALETSLQKLQLDYVDLYLIHWP- 109
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
D D+ ++ WR ++ K+ GL +SIG+ NF+ +QR+ID P+ QIE
Sbjct: 110 -----DPKQDH--YVSAWRELVTLKEQGLIRSIGVCNFHIPHLQRLIDETGIAPTVNQIE 162
Query: 623 LN 628
L+
Sbjct: 163 LH 164
>UniRef50_UPI00015B4912 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 353
Score = 114 bits (275), Expect = 1e-24
Identities = 78/192 (40%), Positives = 106/192 (55%), Gaps = 13/192 (6%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
+LSSG N P+V LGT H V+ E + ALE G HIDT++ Y E+ +G
Sbjct: 32 RLSSGHNFPIVGLGT---HGLNEDVL------ETVLTGALEKGIGHIDTSFVYKNEETIG 82
Query: 272 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM- 448
+ L F++G KRE IF+T+KL + E V ++ SLE L L+Y+D+YLIH P A+
Sbjct: 83 KVLKDWFAKGGKREDIFVTSKLPYYDNHPESVEKYIKLSLEKLGLQYLDMYLIHAPFAVH 142
Query: 449 -----FENDTLLDNVDFLDT-------WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 592
+E T D LDT W+ M K G TKSIG+SNFN+ QI I+
Sbjct: 143 HKEDSYELATNEDGSVVLDTQTDPIAVWKEMEKQVKEGRTKSIGLSNFNETQITNILKEA 202
Query: 593 LEKPSALQIELN 628
KPS LQ+E++
Sbjct: 203 KIKPSNLQVEVH 214
>UniRef50_UPI0000519CC2 Cluster: PREDICTED: similar to CG2767-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG2767-PA
- Apis mellifera
Length = 321
Score = 114 bits (275), Expect = 1e-24
Identities = 82/196 (41%), Positives = 106/196 (54%), Gaps = 14/196 (7%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T+ L +G +P++ GTW + E A+ ALEAGY HIDTA Y E
Sbjct: 5 TILLPNGELMPIIGFGTWQAQE---------KELEDALNIALEAGYRHIDTATSYENEKV 55
Query: 266 VGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
+G L F S+ LKR IFI TKL + E V ++ SL+NL LEY+DLYLIH PI
Sbjct: 56 IGDVLKNWFDSKKLKRSDIFIVTKLPAVGNRAEDVEKWIKTSLQNLRLEYLDLYLIHVPI 115
Query: 443 AMFE--NDTL----------LDN-VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 583
FE D L LDN + ++ W M K G TK+IG+SNFN QI+RI+
Sbjct: 116 G-FEKVGDILHPFDENGHIRLDNSTNHVEIWAEMEKQVKCGRTKAIGLSNFNISQIKRIL 174
Query: 584 DSGLEKPSALQIELNL 631
+ K S LQIEL++
Sbjct: 175 KNTKMKISMLQIELHV 190
>UniRef50_Q03PG5 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Lactobacillus brevis ATCC
367|Rep: Aldo/keto reductase of diketogulonate reductase
family - Lactobacillus brevis (strain ATCC 367 / JCM
1170)
Length = 268
Score = 114 bits (274), Expect = 2e-24
Identities = 66/179 (36%), Positives = 104/179 (58%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T QLS+G IP++ GT+L + D A+ AL+AGY H+D A+ YG E
Sbjct: 3 TTQLSNGVTIPMLGFGTYLID---------SKDVPAAIKTALDAGYRHLDCAHIYGNEPA 53
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VG A+ + G+ R +FIT+K+WN+ ++ + A ++L +L L+Y+DLYLIHWP
Sbjct: 54 VGEAIK---ASGIDRSDLFITSKVWNADQGYDKTLAAFDQTLSDLQLDYLDLYLIHWP-- 108
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
E+D L LDTWR + + ++IG+SNF+++Q++++ + KP QIE
Sbjct: 109 -NEDDFELT----LDTWRVLETLYQQKKVRAIGVSNFSEDQLKQVFEMATVKPMINQIE 162
>UniRef50_Q9VHX4 Cluster: CG2767-PA; n=4; Endopterygota|Rep:
CG2767-PA - Drosophila melanogaster (Fruit fly)
Length = 329
Score = 114 bits (274), Expect = 2e-24
Identities = 71/191 (37%), Positives = 105/191 (54%), Gaps = 13/191 (6%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
L ++G +PV+ +GTW + E A+ ALEAGY HIDTA YG E +
Sbjct: 7 LTFNNGEKMPVIGIGTWQAS---------DEEIETAIDAALEAGYRHIDTAPVYGNEKAI 57
Query: 269 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
GR L + G +KRE +FI TK+ + +V P ++KSLE+L L+YVDLYL+H P
Sbjct: 58 GRVLKRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFT 117
Query: 446 MFENDT---LLDNVDFLDT---------WRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS 589
+ N+ LD ++ W M + GLTKSIG+SNF+++Q+ R++ +
Sbjct: 118 ININEDGSFKLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLKN 177
Query: 590 GLEKPSALQIE 622
+P+ QIE
Sbjct: 178 CKIRPANNQIE 188
>UniRef50_A5PDA8 Cluster: Putative oxidoreductase protein; n=1;
Erythrobacter sp. SD-21|Rep: Putative oxidoreductase
protein - Erythrobacter sp. SD-21
Length = 272
Score = 113 bits (273), Expect = 3e-24
Identities = 71/182 (39%), Positives = 98/182 (53%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
PTL L+ G IP + GTW D QAV A++ GY IDTA YG E
Sbjct: 5 PTLNLNDGRQIPQLGFGTWQMEE---------EDAPQAVSTAIDVGYWLIDTAAIYGNEK 55
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VG+ + + +S+ IF+ TK+WN ++ + A K LE L E+VD+ LIHWP
Sbjct: 56 GVGKGVGE-WSD------IFLQTKIWNDSQGYDRTLRAAEKCLERLGREHVDMLLIHWPC 108
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
E D F+DTW+ +I+ + G KSIG+SNF +E ++RIID P+ QIE
Sbjct: 109 P--EKD------QFVDTWKALIELRDAGKAKSIGVSNFREEDLKRIIDETGVTPALNQIE 160
Query: 623 LN 628
L+
Sbjct: 161 LH 162
>UniRef50_Q9ZBW7 Cluster: Putative oxidoreductase; n=2;
Actinomycetales|Rep: Putative oxidoreductase -
Streptomyces coelicolor
Length = 277
Score = 113 bits (272), Expect = 3e-24
Identities = 71/184 (38%), Positives = 99/184 (53%), Gaps = 1/184 (0%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQ-AVIYALEAGYTHIDTAYKYGI 256
VP + L++G +P + G W QV +D Q AV ALEAGY IDTA YG
Sbjct: 5 VPPIILNNGVEMPQLGFGVW----------QVPDDDAQTAVALALEAGYRSIDTAAIYGN 54
Query: 257 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
E+ GRA+ + GL RE +F+TTKLWNS + + A S+ L LEY+DLYLIHW
Sbjct: 55 EEGTGRAIA---ASGLAREDLFVTTKLWNSDQGYDSTLRAFDTSMAKLGLEYLDLYLIHW 111
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P+ E ++DT++ G ++IG+SNF E ++R+ P+ Q
Sbjct: 112 PMPAKER--------YVDTYKAFEKLLADGRVRAIGVSNFLPEHLERLTAETSVIPAVNQ 163
Query: 617 IELN 628
IEL+
Sbjct: 164 IELH 167
>UniRef50_Q7N0E4 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=2; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Photorhabdus luminescens subsp. laumondii
Length = 292
Score = 113 bits (272), Expect = 3e-24
Identities = 73/182 (40%), Positives = 100/182 (54%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P ++L+ G ++P + LG+W Q +T A AL+ GY IDTA Y E
Sbjct: 5 PIIRLADGNHMPQLGLGSWASDD------QQIAETIHA---ALDIGYRAIDTAAIYNNEK 55
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VG AL + + RE IF+TTKLWN H + AL +SLE L L+YVDLYLIHWP
Sbjct: 56 GVGNALQET---DIPREDIFVTTKLWNDRHLDARA--ALTESLEKLQLDYVDLYLIHWPA 110
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
+ ++ W+ +I+ +K GL +SIG+SNF E IQR+I+ P QIE
Sbjct: 111 PPQDQ--------YVGAWQQLIELQKEGLIRSIGVSNFQPEHIQRLINETGVHPVINQIE 162
Query: 623 LN 628
L+
Sbjct: 163 LH 164
>UniRef50_Q9FJK0 Cluster: Aldose reductase-like protein; n=3; core
eudicotyledons|Rep: Aldose reductase-like protein -
Arabidopsis thaliana (Mouse-ear cress)
Length = 316
Score = 113 bits (272), Expect = 3e-24
Identities = 64/188 (34%), Positives = 108/188 (57%), Gaps = 9/188 (4%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
+L G IP++ +GT+ + + T AV A++ GY H DTA YG E+ +G
Sbjct: 7 RLRCGETIPLLGMGTYCPQKDR-------ESTISAVHQAIKIGYRHFDTAKIYGSEEALG 59
Query: 272 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
AL + S G ++R+ +F+T+KLW+S H I AL ++L+ + L+Y+D YL+HWPI +
Sbjct: 60 TALGQAISYGTVQRDDLFVTSKLWSSDHH--DPISALIQTLKTMGLDYLDNYLVHWPIKL 117
Query: 449 F--------ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 604
+ D ++ +TW+GM ++GL +SIG+SNF+ ++I ++D P
Sbjct: 118 KPGVSEPIPKEDEFEKDLGIEETWQGMERCLEMGLCRSIGVSNFSSKKIFDLLDFASVSP 177
Query: 605 SALQIELN 628
S Q+E++
Sbjct: 178 SVNQVEMH 185
>UniRef50_UPI0000E4A7CE Cluster: PREDICTED: similar to LOC553452
protein; n=6; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to LOC553452 protein -
Strongylocentrotus purpuratus
Length = 321
Score = 113 bits (271), Expect = 4e-24
Identities = 69/190 (36%), Positives = 105/190 (55%), Gaps = 14/190 (7%)
Frame = +2
Query: 95 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
L G +P++ GTW + G+V++ A++ GY HID A YG E VG
Sbjct: 10 LPGGRKLPLLGFGTWQIKPEEVGRVIET----------AIDCGYRHIDEASLYGNEKGVG 59
Query: 272 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA- 445
+ K +G +KRE +F+T+KLW + +V P+ R+SL +L L Y+DL+LIH P +
Sbjct: 60 DGIKAKIDDGTIKREDLFVTSKLWVTDSHPSRVEPSCRQSLSDLGLAYLDLFLIHCPTSA 119
Query: 446 --------MFENDTLL--DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 595
M +N + D +D++DTWR M GL ++IG+SNF QIQR++D
Sbjct: 120 VGGKGPFPMDDNGLFIGDDTIDYVDTWRIMESLVDKGLVRAIGVSNFTVAQIQRVLDLPP 179
Query: 596 EKPSA-LQIE 622
+ P A +Q+E
Sbjct: 180 KYPIANVQVE 189
>UniRef50_P28475 Cluster: NADP-dependent D-sorbitol-6-phosphate
dehydrogenase; n=71; Magnoliophyta|Rep: NADP-dependent
D-sorbitol-6-phosphate dehydrogenase - Malus domestica
(Apple) (Malus sylvestris)
Length = 310
Score = 113 bits (271), Expect = 4e-24
Identities = 69/194 (35%), Positives = 102/194 (52%), Gaps = 15/194 (7%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T+ LSSG +PV+ LG W + ++ ++ ++ A++ GY H D A Y E
Sbjct: 3 TVTLSSGYEMPVIGLGLWRLEK---------DELKEVILNAIKIGYRHFDCAAHYKSEAD 53
Query: 266 VGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VG AL + F GL KRE +FITTK+WNS H V+ A + SLE L ++Y+DLYL+H+P+
Sbjct: 54 VGEALAEAFKTGLVKREELFITTKIWNSDHGH--VVEACKNSLEKLQIDYLDLYLVHYPM 111
Query: 443 -----------AMFENDTLLD---NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 580
++ D +LD + TW GM LGL +SIG+SN+ +
Sbjct: 112 PTKHNAIGKTASLLGEDKVLDIDVTISLQQTWEGMEKTVSLGLVRSIGLSNYELFLTRDC 171
Query: 581 IDSGLEKPSALQIE 622
+ KP+ Q E
Sbjct: 172 LAYSKIKPAVSQFE 185
>UniRef50_A1D4E3 Cluster: D-xylose reductase (Xyl1), putative; n=5;
Pezizomycotina|Rep: D-xylose reductase (Xyl1), putative
- Neosartorya fischeri (strain ATCC 1020 / DSM 3700 /
NRRL 181)(Aspergillus fischerianus (strain ATCC 1020 /
DSM 3700 / NRRL 181))
Length = 321
Score = 112 bits (270), Expect = 6e-24
Identities = 68/200 (34%), Positives = 108/200 (54%), Gaps = 17/200 (8%)
Frame = +2
Query: 74 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKY 250
+ P+ +L+SG ++P+V G W +V N+T IY A++AGY D A Y
Sbjct: 1 MTTPSTKLNSGYDMPLVGFGLW----------KVNNETCADQIYHAIKAGYRLFDGACDY 50
Query: 251 GIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL 427
G E + G+ + + EG+ KRE +FI +KLWNS+H+ ++V P RK L + L+Y DL++
Sbjct: 51 GNEVEAGKGVARAIQEGIVKREDLFIVSKLWNSFHDGDRVEPICRKQLADWGLDYFDLFI 110
Query: 428 IHWPIAM--------------FENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQ 562
+H+PIA+ EN+ L N +TW M L +SIG+SNF+
Sbjct: 111 VHFPIALKYVDPAVRYPPGWLSENNKLEFSNASIQETWTAMESLVDKKLARSIGVSNFSA 170
Query: 563 EQIQRIIDSGLEKPSALQIE 622
+ + ++ +P+ LQIE
Sbjct: 171 QLLMDLLRYARIRPATLQIE 190
>UniRef50_Q22352 Cluster: Putative uncharacterized protein T08H10.1;
n=2; Caenorhabditis|Rep: Putative uncharacterized
protein T08H10.1 - Caenorhabditis elegans
Length = 333
Score = 112 bits (269), Expect = 8e-24
Identities = 72/200 (36%), Positives = 108/200 (54%), Gaps = 14/200 (7%)
Frame = +2
Query: 74 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYK 247
+ V ++ L++G +P+ LGTW QV ++ E V AL+AGY IDTA+
Sbjct: 1 MTVDSIPLNTGAQLPLFGLGTW----------QVKDEAELTVALRAALDAGYRLIDTAHL 50
Query: 248 YGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 424
Y E +G+ L + S G LKRE IF+T+KL + H E V + L+ L LEY+DLY
Sbjct: 51 YQNEHIIGKVLHEYISSGKLKREDIFVTSKLPFTAHAPEDVPKCVESQLKALQLEYIDLY 110
Query: 425 LIHWPI----------AMFENDTL-LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 571
LIH P + EN L + + +DTWR + K G K++G+SNF+ Q+
Sbjct: 111 LIHCPFPFKHQEGSFAPLMENGELAVTEIAHIDTWRALEKLYKEGKLKALGVSNFSCNQL 170
Query: 572 QRIIDSGLEKPSALQIELNL 631
Q + D+ KP+ Q+E ++
Sbjct: 171 QALYDAAEVKPANQQVECHI 190
>UniRef50_Q7ZA52 Cluster: Aldose reductase; n=6; Pezizomycotina|Rep:
Aldose reductase - Magnaporthe grisea (Rice blast
fungus) (Pyricularia grisea)
Length = 312
Score = 112 bits (269), Expect = 8e-24
Identities = 66/190 (34%), Positives = 109/190 (57%), Gaps = 14/190 (7%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L++G IP LGTW G KG + ++AV+ A+++GY ID AY YG E++VG+
Sbjct: 8 LNTGAKIPAFGLGTWQGD--KGVI-------KEAVLTAIKSGYRLIDGAYVYGNEEEVGQ 58
Query: 275 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 451
+ + S G+ KRE +F+ +K W +Y R ++ L +SL+ L L+YVDLYL+HWPI M
Sbjct: 59 GIREAISSGIVKREDLFVVSKCWATYTTRCEL--GLDQSLKLLGLDYVDLYLVHWPILMN 116
Query: 452 E--ND-----------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 592
ND ++ + +DTW+ M G TK++G+SN+++ +++++
Sbjct: 117 PEGNDEKFPKHADGSRDIIHTHNHVDTWKLMEKLPATGKTKAVGVSNYSKAWLEQLLPHA 176
Query: 593 LEKPSALQIE 622
P+ Q+E
Sbjct: 177 TTVPAVNQVE 186
>UniRef50_Q9ZUJ6 Cluster: T2K10.1 protein; n=16; core
eudicotyledons|Rep: T2K10.1 protein - Arabidopsis
thaliana (Mouse-ear cress)
Length = 176
Score = 111 bits (268), Expect = 1e-23
Identities = 65/178 (36%), Positives = 103/178 (57%), Gaps = 14/178 (7%)
Frame = +2
Query: 80 VPTLQLSSGGN----IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYK 247
VPTL + SG + +PV+ GT P+ +++ T VI A++ GY H DT+ +
Sbjct: 6 VPTLAIRSGPSGHHSMPVLGFGTAASPLPEPTMLKET------VIEAIKLGYRHFDTSPR 59
Query: 248 YGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 421
Y E+ +G AL + S GL R F+TTKLW + V+PA+++SL+NL L+Y+DL
Sbjct: 60 YQTEEPIGEALAEAVSLGLVRSRSEFFVTTKLWCADAHGGLVVPAIKRSLKNLKLDYLDL 119
Query: 422 YLIHWPIAM--------FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 571
Y+IHWP++ + D + +DF W M + ++LGL K IG+SNF+ +++
Sbjct: 120 YIIHWPVSSKPGKYKFPIDEDDFMP-MDFEVVWSEMEECQRLGLAKCIGVSNFSCKKL 176
>UniRef50_Q41E86 Cluster: 2,5-didehydrogluconate reductase; n=2;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Exiguobacterium sibiricum 255-15
Length = 274
Score = 111 bits (267), Expect = 1e-23
Identities = 61/146 (41%), Positives = 84/146 (57%)
Frame = +2
Query: 191 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVI 370
+AV AL GY IDTA Y E VGRAL G+ RE IF+TTK+WN E+ +
Sbjct: 29 EAVREALRVGYRSIDTAMIYENEAGVGRALK---DSGIPREDIFLTTKVWNKDQGYERTL 85
Query: 371 PALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGIS 550
A SL+ L ++YVDLYLIHWP+ D ++DTWR + + G K+IG+S
Sbjct: 86 AAFETSLQKLGVDYVDLYLIHWPMP--------DEDLYMDTWRALEQLYRDGKAKAIGVS 137
Query: 551 NFNQEQIQRIIDSGLEKPSALQIELN 628
NF+ + R+++ G P+ QIEL+
Sbjct: 138 NFHIPHLTRVLEEGTVVPAVNQIELH 163
>UniRef50_Q6RZX1 Cluster: Gld1; n=22; Pezizomycotina|Rep: Gld1 -
Trichoderma atroviride (Hypocrea atroviridis)
Length = 327
Score = 111 bits (266), Expect = 2e-23
Identities = 68/199 (34%), Positives = 106/199 (53%), Gaps = 18/199 (9%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T L++G IP V GT+ KG +T AV AL+ GY H+D A+ Y ED+
Sbjct: 14 TYTLNTGAKIPAVGFGTFANEGAKG-------ETYAAVTKALDVGYRHLDCAWFYLNEDE 66
Query: 266 VGRALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
VG A+ + + R+ +FI TK+WN HE E V + + S ENL ++Y+DL+L+HWP
Sbjct: 67 VGDAIRDFLARRPDVTRKDLFICTKVWNHLHEPEDVKWSAKNSCENLKVDYIDLFLVHWP 126
Query: 440 IAMFE----------------NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 571
IA + N L +N + TWR M + G+ K+IG+SN+ +
Sbjct: 127 IAAEKNADRTVKIGPDGKYVINKALTENPE--PTWRAMEELVDSGIVKAIGVSNWTIPGL 184
Query: 572 QRIIDSGLEKPSALQIELN 628
+++++ KP+ QIE++
Sbjct: 185 KQLLEFARIKPAVNQIEIH 203
>UniRef50_Q568D7 Cluster: Zgc:110366; n=7; Euteleostomi|Rep:
Zgc:110366 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 289
Score = 110 bits (265), Expect = 2e-23
Identities = 67/186 (36%), Positives = 103/186 (55%), Gaps = 1/186 (0%)
Frame = +2
Query: 74 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKY 250
L P + L +G NIP++ LGT H + +AV+YAL E G HIDTA +Y
Sbjct: 11 LSCPAVPLHNGLNIPILGLGT--SH--------YGGYSHEAVLYALQECGIRHIDTAKRY 60
Query: 251 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 430
G E+ +G+A+T+ G++RE +++TTKLW + + A R S L ++Y+DLYL+
Sbjct: 61 GCEEALGKAVTES---GVQREELWVTTKLWPGDYGYQSTKQACRDSRARLGVDYLDLYLM 117
Query: 431 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 610
HWP +M + L+TWR + + GL ++IG+SNF + + DSG P
Sbjct: 118 HWPDSMVPGRS--SQEVRLETWRALEELYDEGLCRAIGVSNFLIPHLNELKDSGGIVPHV 175
Query: 611 LQIELN 628
Q+E +
Sbjct: 176 NQVEFH 181
>UniRef50_Q890A0 Cluster: Oxidoreductase; n=6; Lactobacillales|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 282
Score = 110 bits (265), Expect = 2e-23
Identities = 71/180 (39%), Positives = 96/180 (53%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
QL++G NIP VA GTW P G+ T QAV AL AGY HIDTA Y E VG
Sbjct: 9 QLANGVNIPKVAFGTW--QIPGGEA------TYQAVRAALAAGYRHIDTALAYQNEASVG 60
Query: 272 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 451
+A+ G+ RE IF+TTKL + + +SL+NL L+YVDLYL+H P
Sbjct: 61 QAIR---DSGIPREQIFVTTKLPAETKSYQGALNDFDRSLKNLGLDYVDLYLVHAPWPWG 117
Query: 452 ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNL 631
+ + D + LD W+ M + G K+IG+SNF ++ I++ P QI+ L
Sbjct: 118 QVGRVYDEAN-LDVWQAMEAIYQSGRAKAIGVSNFAVRDLKNILNQATIPPMVNQIQYYL 176
>UniRef50_Q24C22 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=4; Oligohymenophorea|Rep: Oxidoreductase,
aldo/keto reductase family protein - Tetrahymena
thermophila SB210
Length = 297
Score = 110 bits (265), Expect = 2e-23
Identities = 65/184 (35%), Positives = 100/184 (54%), Gaps = 1/184 (0%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VP L GG+IP + GT+ ++ Q ND V AL+ GYTHIDTA Y E
Sbjct: 13 VPILNFREGGSIPQIGYGTY-------ELRQ--NDCIIGVTEALKIGYTHIDTASVYRNE 63
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+ + + + G+KRE +FIT+K+ EQ A++ L LN++Y+D LIHWP
Sbjct: 64 QDIAKVIHNP-AYGIKREDLFITSKISPGEQGYEQAKKAVQDMLTRLNIKYLDCVLIHWP 122
Query: 440 -IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
++ + + L+TW+ +I+ +K G+ K IG+SNFN +Q +I+ KP Q
Sbjct: 123 GVSKLPPNDPKNAQIRLETWKALIELRKAGVIKHIGVSNFNINHLQHLIEKSEFKPEMNQ 182
Query: 617 IELN 628
E++
Sbjct: 183 FEIH 186
>UniRef50_UPI0000E45E29 Cluster: PREDICTED: similar to aldose
reductase; n=1; Strongylocentrotus purpuratus|Rep:
PREDICTED: similar to aldose reductase -
Strongylocentrotus purpuratus
Length = 274
Score = 110 bits (264), Expect = 3e-23
Identities = 61/148 (41%), Positives = 89/148 (60%), Gaps = 1/148 (0%)
Frame = +2
Query: 188 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQ 364
E AV A++ GY HID A+ YG E +VG L +KF + KRE IFIT+KLWN+ H +
Sbjct: 13 EAAVKAAIDCGYRHIDCAHVYGNEAEVGAGLKEKFDANVVKREDIFITSKLWNNKHHPDD 72
Query: 365 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 544
V A +L+NL L YVDLYL+HWP+A + L+ + G K+IG
Sbjct: 73 VEQACDITLKNLQLSYVDLYLMHWPMAYQAMEKLVTS----------------GKCKAIG 116
Query: 545 ISNFNQEQIQRIIDSGLEKPSALQIELN 628
+SNF+ + ++R+I+ +P+ LQ+EL+
Sbjct: 117 LSNFSMKMMKRVIEKATIQPANLQVELH 144
>UniRef50_A0JRJ3 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinobacteria (class)|Rep: 2,5-didehydrogluconate
reductase - Arthrobacter sp. (strain FB24)
Length = 276
Score = 110 bits (264), Expect = 3e-23
Identities = 65/182 (35%), Positives = 98/182 (53%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P ++L+ G IP + LGTW P + AV+ A+E GY HIDTA KYG E
Sbjct: 5 PVIELNDGHRIPQIGLGTW----PLDD-----HQVAAAVVNAVEGGYRHIDTAVKYGNEK 55
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VG + S GL R +FITTKL + +++ + L SL+ L L+YVDL LIHWP+
Sbjct: 56 GVGNGIR---SSGLDRSELFITTKLDGEFQGQDRAVAGLDGSLKRLGLDYVDLLLIHWPL 112
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
+ +F+ TW+ + G +SIG+SNF ++R++ + P+ QI+
Sbjct: 113 PRRD--------EFISTWKTFERLQADGKVRSIGVSNFKPAHLERLMAACDVVPAVNQIQ 164
Query: 623 LN 628
++
Sbjct: 165 VS 166
>UniRef50_Q8ET73 Cluster: 2,5-diketo-D-gluconate reductase; n=12;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Oceanobacillus iheyensis
Length = 280
Score = 109 bits (262), Expect = 5e-23
Identities = 67/183 (36%), Positives = 101/183 (55%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+P + L G IP V GT+ R G ND QA+ A++ GY IDTAY Y E
Sbjct: 5 IPNVTLHDGLTIPKVGFGTY---RLNG------NDGVQAINNAIDHGYRLIDTAYNYENE 55
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
VG A+ + + RE + IT+KL YH ++ + +++SL NL+Y DLYLIHWP
Sbjct: 56 GTVGEAVRRSSTP---REQLLITSKLPGRYHHYDKAVTTIQESLYRANLDYYDLYLIHWP 112
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
+ + D +++ W+ +I+AK+ G +SIG+ NF E ++R+ E P+ QI
Sbjct: 113 ------NPIQD--IYVEAWQALIEAKRRGYIRSIGVCNFLPEHLERLKQETGELPTINQI 164
Query: 620 ELN 628
EL+
Sbjct: 165 ELH 167
>UniRef50_A7CWF9 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Opitutaceae bacterium TAV2
Length = 347
Score = 109 bits (262), Expect = 5e-23
Identities = 65/197 (32%), Positives = 100/197 (50%), Gaps = 14/197 (7%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
+P L+SG +P + +GT+ H G+V +V A E GY H D A Y
Sbjct: 16 IPQRTLASGARMPAIGMGTFGSDHAAPGEVAA-------SVYAAAELGYRHFDCAAVYSN 68
Query: 257 EDQVGRALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 430
E ++G + + G++RE ++IT+KLWN H VIPA KSL +L L+Y+DLYLI
Sbjct: 69 EREIGATFRRILTSNTGIRREDLWITSKLWNDKHAEADVIPAFEKSLRDLGLDYLDLYLI 128
Query: 431 HWPIAMFE------NDTLLD-----NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQR 577
HWP F + D + +F+ TWR + GL + IG SN ++Q
Sbjct: 129 HWPFPNFHPPGCDVSSRSPDARPYIHAEFMKTWRQLETLHDRGLVRHIGTSNMTIAKLQL 188
Query: 578 IIDSGLEKPSALQIELN 628
++ +P+ ++EL+
Sbjct: 189 LLRDARVRPAVNEMELH 205
>UniRef50_A6W8E7 Cluster: 2,5-didehydrogluconate reductase; n=3;
Actinomycetales|Rep: 2,5-didehydrogluconate reductase -
Kineococcus radiotolerans SRS30216
Length = 289
Score = 109 bits (262), Expect = 5e-23
Identities = 69/186 (37%), Positives = 101/186 (54%), Gaps = 1/186 (0%)
Frame = +2
Query: 74 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKY 250
+ VPT+ L+ G IP + G V Q+ DT QAV AL+ GY HIDTA Y
Sbjct: 10 MTVPTILLNDGREIPQLGFG----------VFQIEPGDTAQAVKTALDLGYRHIDTAQMY 59
Query: 251 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 430
G E +V + + G+ R+ I++T+KL N +HE + A+ S+E L +DLYLI
Sbjct: 60 GNEAEVAQGIA---DSGVPRDEIWVTSKLNNGFHEPDAARKAVDDSVEKLRGP-IDLYLI 115
Query: 431 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 610
HWP+ TL DF+ TW+ + +A+ G +SIG+SNF +QR+ P+
Sbjct: 116 HWPLP-----TLYGG-DFVSTWKVLEEARAAGKLRSIGVSNFQVNHLQRLAQEATVVPAV 169
Query: 611 LQIELN 628
QIE++
Sbjct: 170 NQIEVH 175
>UniRef50_Q17G72 Cluster: Aldo-keto reductase; n=9;
Endopterygota|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 316
Score = 108 bits (260), Expect = 9e-23
Identities = 70/189 (37%), Positives = 98/189 (51%), Gaps = 11/189 (5%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
+ +G +P + GTW + E+A+ ALEAGY HIDTA Y E +
Sbjct: 7 ITFENGTTMPALGFGTWRAS---------DEEVEKALNEALEAGYRHIDTAPVYLNEKTI 57
Query: 269 GRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
G+ L + G + R+ +FI TKL V L+ SL++L LEYVDLY +H P
Sbjct: 58 GKVLKEWMDAGKVTRDELFIVTKLPPHGTRASTVEKFLKNSLDDLQLEYVDLYHVHVPFT 117
Query: 446 MFEND----------TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 595
+ E D L D + W+ M + + GL ++IG+SNFNQ QIQRI+D+
Sbjct: 118 VPEVDGPFLVEDGLIVLETTTDHVALWKAMEEVYEAGLARNIGLSNFNQRQIQRILDNCQ 177
Query: 596 EKPSALQIE 622
KP+ LQIE
Sbjct: 178 IKPANLQIE 186
>UniRef50_Q1VRG6 Cluster: YvgN; n=1; Psychroflexus torquis ATCC
700755|Rep: YvgN - Psychroflexus torquis ATCC 700755
Length = 280
Score = 107 bits (258), Expect = 2e-22
Identities = 69/180 (38%), Positives = 96/180 (53%), Gaps = 2/180 (1%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKG-KVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
L+ G IP+V GT+ + +G K +Q + AL GY IDT Y E+ VG
Sbjct: 5 LNDGNRIPIVGFGTYKANEEEGIKSIQKS---------ALTLGYRLIDTVAIYQNEEAVG 55
Query: 272 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI-AM 448
+A+ + G+ RE IF+TTKLW +Q AL +SL L+L Y+DLYLIHWP A+
Sbjct: 56 KAIKAR---GVLREEIFVTTKLWRENLGYKQTRIALDESLRKLDLNYIDLYLIHWPANAI 112
Query: 449 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
D N DTWR M + + G KS+G+SNF E ++ + + PS QIE +
Sbjct: 113 NYKDWQKTNA---DTWRAMEELQAEGKIKSLGVSNFWPEHLEALFQTAKVSPSVNQIEFH 169
>UniRef50_Q03XK0 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=3; Lactobacillales|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 292
Score = 107 bits (258), Expect = 2e-22
Identities = 65/179 (36%), Positives = 98/179 (54%), Gaps = 1/179 (0%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L+SG +P++ G + VQ +QAV+ A++ GY IDTA YG E +VG
Sbjct: 6 LASGIEMPLLGFGVFQ--------VQEKGAAKQAVLDAIKTGYRLIDTAASYGNEREVGE 57
Query: 275 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 451
A+ + ++G+ KRE +F+T+K+W +Q A++ SL+ LNL+Y+DLYLIH P
Sbjct: 58 AILEAINQGIVKREELFVTSKMWVQDVSAQQATAAIQSSLQRLNLDYLDLYLIHQPYN-- 115
Query: 452 ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
D WR M A + G K+IG+SNF+ Q+ + + KP QIE+N
Sbjct: 116 ---------DVFGAWRAMESAYRSGQLKAIGVSNFDIAQLTNLAEFSDIKPMLNQIEVN 165
>UniRef50_Q9HGY0 Cluster: Glycerol dehydrogenase; n=8;
Saccharomycetaceae|Rep: Glycerol dehydrogenase -
Zygosaccharomyces rouxii (Candida mogii)
Length = 310
Score = 107 bits (258), Expect = 2e-22
Identities = 75/200 (37%), Positives = 110/200 (55%), Gaps = 19/200 (9%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
TL+L++G IP V LGTW R K N+ +AVI AL+AGY HID A YG E +
Sbjct: 10 TLKLNTGQTIPQVGLGTW---RSK------ENEGYKAVIEALKAGYRHIDGAAVYGNEGE 60
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VG+A+ G+ R IF+TTKLW ++ Q AL +SL+ L L+YV LYL+HWP+
Sbjct: 61 VGKAIQ---DSGVPRNEIFLTTKLWCTHQRNPQ--EALDQSLQRLGLDYVGLYLVHWPVP 115
Query: 446 M----FENDTLLD---------NVD----FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 574
+ ++ L +VD F+ TW M + G TK+IG+SNF+ ++
Sbjct: 116 LRTENIKDGNLFQFAEKPDGSKDVDLEWNFIKTWELMQKLLESGKTKAIGVSNFSVNNLK 175
Query: 575 RIIDSGLEK--PSALQIELN 628
++ + K P+ Q+E +
Sbjct: 176 DLLAAPTTKVTPAVNQVEFH 195
>UniRef50_Q4P4P1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 322
Score = 107 bits (258), Expect = 2e-22
Identities = 68/189 (35%), Positives = 106/189 (56%), Gaps = 3/189 (1%)
Frame = +2
Query: 65 SAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDT 238
S + ++L++G IP VALG V + ND TE A +A +AGY HID+
Sbjct: 11 SGNISTQRIKLNNGQEIPQVALG----------VYKAPNDGSTENACKWAFDAGYRHIDS 60
Query: 239 AYKYGIEDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYV 415
A +Y E+ VGRAL + E + R IFIT+KLW++ H++ A+ SL+ LN++Y+
Sbjct: 61 AARYMNEESVGRALAEWTKENNVPRSEIFITSKLWDADHDK--AAAAIEDSLKKLNVDYM 118
Query: 416 DLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGL 595
D+YL+H P M L+ W+ + +A G K+IG+SNF+ E++ ++ +
Sbjct: 119 DMYLMHSPGTMGAEKR-------LEAWKALEEAVDAGKIKTIGVSNFDVEELDHLLANCR 171
Query: 596 EKPSALQIE 622
KP+ QIE
Sbjct: 172 IKPAVNQIE 180
>UniRef50_P15339 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=6; Actinomycetales|Rep: 2,5-diketo-D-gluconic acid
reductase B - Corynebacterium sp. (strain SHS752001)
Length = 277
Score = 107 bits (258), Expect = 2e-22
Identities = 62/183 (33%), Positives = 103/183 (56%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+PT+ L+ G LGT+ +G A++ A+++GY +DTA Y E
Sbjct: 4 IPTISLNDGRPFAEPGLGTYNLRGDEGVA---------AMVAAIDSGYRLLDTAVNYENE 54
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+VGRA+ + + R+ + + +K+ H R + + ++R SL+ L L+ +DL LIHWP
Sbjct: 55 SEVGRAVR---ASSVDRDELIVASKIPGRQHGRAEAVDSIRGSLDRLGLDVIDLQLIHWP 111
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
N ++ +LDTWRGMIDA++ GL +SIG+SNF + ++ +ID P+ Q+
Sbjct: 112 -----NPSV---GRWLDTWRGMIDAREAGLVRSIGVSNFTEPMLKTLIDETGVTPAVNQV 163
Query: 620 ELN 628
EL+
Sbjct: 164 ELH 166
>UniRef50_A6ESC0 Cluster: ARA1; n=1; unidentified eubacterium
SCB49|Rep: ARA1 - unidentified eubacterium SCB49
Length = 280
Score = 107 bits (256), Expect = 3e-22
Identities = 63/179 (35%), Positives = 94/179 (52%), Gaps = 2/179 (1%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
+L++ NIP + GTW P G+ A+ A++AGY HID A Y E VG
Sbjct: 6 KLNNNINIPAIGFGTW--QTPDGQTAI------NAIKTAIDAGYKHIDAAAIYKNEKGVG 57
Query: 272 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA-- 445
+ + + R+ +F+T+K+WN E + A ++ +L L+Y+DLYLIHWP A
Sbjct: 58 LGIKEA---NIDRKDLFVTSKVWNEQRGYENTLKAFDNTINDLQLDYLDLYLIHWPAAAH 114
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
FEN L+N DTW M K G K++G+SNF + + ++ KP+ QIE
Sbjct: 115 QFENWKQLNN----DTWSAMEKLYKDGKIKALGVSNFMEHHLTPLLQHATIKPTVNQIE 169
>UniRef50_A7PNI3 Cluster: Chromosome chr1 scaffold_22, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_22, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 360
Score = 107 bits (256), Expect = 3e-22
Identities = 67/189 (35%), Positives = 108/189 (57%), Gaps = 11/189 (5%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L++ IP + LGTW G + V +AV AL GY ID A+ YG E +VG
Sbjct: 14 LNTKAKIPAIGLGTW----QSGGDLCV-----EAVKRALSEGYRQIDCAHLYGNEVEVGE 64
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP-IAMF 451
AL + F+ LKRE +F+T+KL+ + + ++ ++R SL+NL + Y+DLYL+HWP I F
Sbjct: 65 ALAEAFNGSLKREDVFLTSKLYCTMNSLNKIENSVRVSLKNLGVTYLDLYLMHWPDITAF 124
Query: 452 ------ENDTLLDNVDFLD----TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK 601
+++ D+ FL+ W+ M +LGL ++IG+SNF +QI+ ++
Sbjct: 125 GDATDPPSNSGNDHRQFLNRLKKAWKAMEGLIELGLVRAIGVSNFGVQQIKELLKFAKIV 184
Query: 602 PSALQIELN 628
P+ Q++L+
Sbjct: 185 PAVNQVKLH 193
>UniRef50_Q6C2L0 Cluster: Yarrowia lipolytica chromosome F of strain
CLIB122 of Yarrowia lipolytica; n=3; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome F of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 324
Score = 107 bits (256), Expect = 3e-22
Identities = 71/201 (35%), Positives = 112/201 (55%), Gaps = 17/201 (8%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
I + +L+ G +IP + LGT G V E+ V A++ GY HIDTA+ YG
Sbjct: 3 ITDSFKLNDGHSIPALGLGT----ASDGNV-------EEVVYAAIKNGYRHIDTAFIYGS 51
Query: 257 EDQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
E VG+ + + E L KRE++F+TTK+W +++ R V +L SL++L+L+YVDL L+H
Sbjct: 52 EVDVGKGIKRAIDEELVKRENLFVTTKVWPTFYNR--VSESLDISLKDLSLDYVDLLLVH 109
Query: 434 WPIAMF------------ENDTLLDNVDFLDTW---RGMIDAKKL-GLTKSIGISNFNQE 565
WP+++ D + D LD W I+ +KL G TKSIG+SN ++
Sbjct: 110 WPVSLLADSDDPRAIYLVNTDGSVRYSDSLDDWITTYKQIEEEKLSGRTKSIGVSNVSEV 169
Query: 566 QIQRIIDSGLEKPSALQIELN 628
++R++D P+ Q E++
Sbjct: 170 YLKRLLDQVKTVPAVNQFEIH 190
>UniRef50_Q5HR31 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Staphylococcus|Rep: Oxidoreductase,
aldo/keto reductase family - Staphylococcus epidermidis
(strain ATCC 35984 / RP62A)
Length = 279
Score = 106 bits (255), Expect = 4e-22
Identities = 66/178 (37%), Positives = 100/178 (56%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L++G +P V LG + K+ E+ V AL+AGY DTAY YG E +G
Sbjct: 8 LNNGYPMPAVGLGVY-------KIAD--EQMEEVVRTALDAGYRAFDTAYFYGNEKALGS 58
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 454
AL K S ++R+ +FIT+KLWN Y +Q I KSL+NL L+Y+DL+LIHWP E
Sbjct: 59 AL--KHSN-VERDELFITSKLWNDYQGYDQTIEYFNKSLDNLGLDYLDLFLIHWPC---E 112
Query: 455 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
ND L ++++++ + + G K+IG+ NF +++++ P QIEL+
Sbjct: 113 NDQL-----YIESYKALEHLYEEGKIKAIGVCNFKIHHLEKLMKETKITPQVNQIELH 165
>UniRef50_Q5FKI1 Cluster: Reductase-dehydrogenase; n=1;
Lactobacillus acidophilus|Rep: Reductase-dehydrogenase -
Lactobacillus acidophilus
Length = 271
Score = 106 bits (255), Expect = 4e-22
Identities = 66/182 (36%), Positives = 98/182 (53%), Gaps = 3/182 (1%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI-YALEAGYTHIDTAYKYGIEDQVG 271
L++G IP + LGTWL + ND V+ A+ GY DTA YG E VG
Sbjct: 9 LNNGEKIPQIQLGTWL----------INNDEVNKVVRQAVNIGYRGFDTAKDYGNESGVG 58
Query: 272 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 451
+ + ++ ++R IF+TTKL + + E A+ +L+ LEY+DL LIH P
Sbjct: 59 KGI---WNSDIERSDIFLTTKLPTAVKDYEGTKKAIDAALDKFGLEYIDLLLIHSPQPWI 115
Query: 452 ENDTLLDN--VDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 625
E + D L+ WR M +A K G +SIG+SNF QE I+ I+++G P+ QIE+
Sbjct: 116 EVNRTNDRHFKGNLENWRAMEEAVKAGKVRSIGVSNFLQEDIENIVNNGTITPAVNQIEV 175
Query: 626 NL 631
++
Sbjct: 176 HI 177
>UniRef50_Q68ST9 Cluster: Reductase AKOR2; n=2; Pleurotus
djamor|Rep: Reductase AKOR2 - Pleurotus djamor
Length = 306
Score = 106 bits (255), Expect = 4e-22
Identities = 65/195 (33%), Positives = 108/195 (55%), Gaps = 13/195 (6%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P + L++G +P +ALG W G + + ++ + AL++GY HIDTA Y E
Sbjct: 5 PPIVLNTGARMPALALGGWAGLTEEERT-----QAKEWFLTALKSGYRHIDTAQIYYTEK 59
Query: 263 QVGRALTKKFSEGLKRESIFITTKL-WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
VG A+ + G+ RE +FITTKL WN +H R V + +KSLENL EY+DLYL+H+P
Sbjct: 60 SVGNAIRES---GIPREELFITTKLPWN-HHSR--VAESFQKSLENLGTEYIDLYLVHFP 113
Query: 440 IAMFENDT------------LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 583
+F ++T ++++ D W + G K+IG+SN++ + ++ ++
Sbjct: 114 QRVFYDETTDFPRNPDGSIKVVNSPTLNDVWADVETLLDTGKVKAIGVSNYSIKTLEELL 173
Query: 584 DSGLEKPSALQIELN 628
+ P+ Q+EL+
Sbjct: 174 KTAKVVPAVNQVELH 188
>UniRef50_Q0CLQ2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 301
Score = 106 bits (255), Expect = 4e-22
Identities = 75/211 (35%), Positives = 108/211 (51%), Gaps = 32/211 (15%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
+ +LSSG ++P V LGTWL +P ++ E AV AL GY HID A Y E++
Sbjct: 6 SFKLSSGYDMPAVGLGTWLS-KP--------HEVENAVETALRLGYRHIDAAACYLNENE 56
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL------ 427
VG K G+ R+ IFIT+KLWN++H + V A+ K+L++L +Y+DLYL
Sbjct: 57 VGNGWKKS---GVPRDQIFITSKLWNTHHHPDHVEEAVNKTLKDLQTDYLDLYLVFPSLL 113
Query: 428 --------------IHWPIAM-FENDTL-----------LDNVDFLDTWRGMIDAKKLGL 529
IHWP+A N+TL L N+ DTW + G
Sbjct: 114 VLIHDLLSLLTNNKIHWPVAFEHTNETLTPIDPVSKRFRLANIPIADTWAALEKLVDAGK 173
Query: 530 TKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
+SIG+SNF E+I+ ++ + P+ QIE
Sbjct: 174 VRSIGVSNFTIEKIEELLKTARIPPAVNQIE 204
>UniRef50_Q28P63 Cluster: Aldo/keto reductase; n=4;
Rhodobacteraceae|Rep: Aldo/keto reductase - Jannaschia
sp. (strain CCS1)
Length = 276
Score = 106 bits (254), Expect = 5e-22
Identities = 66/183 (36%), Positives = 94/183 (51%), Gaps = 1/183 (0%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE-QAVIYALEAGYTHIDTAYKYGIE 259
P ++ G IP V G W QV D + V A+E GY ID AY Y E
Sbjct: 5 PVIKFHDGAQIPQVGFGIW----------QVPQDIAGETVRSAIEIGYRMIDGAYLYMNE 54
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+G L + GL R+ +F+TTK+WN+ + ++ +SL+ + +E +DL LIHWP
Sbjct: 55 AGLGEGLR---ASGLPRDEVFVTTKVWNNEQGAAKARASVERSLKTIGVEQLDLVLIHWP 111
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
+ D +L+TW+ D + GL +SIG SNFN + ++RII E P QI
Sbjct: 112 VP--SQDL------YLETWKAFQDMRDEGLMRSIGTSNFNADHLERIIAETGEAPVLNQI 163
Query: 620 ELN 628
ELN
Sbjct: 164 ELN 166
>UniRef50_Q4JX70 Cluster: Putative oxidoreductase; n=1;
Corynebacterium jeikeium K411|Rep: Putative
oxidoreductase - Corynebacterium jeikeium (strain K411)
Length = 285
Score = 105 bits (251), Expect = 1e-21
Identities = 66/185 (35%), Positives = 102/185 (55%), Gaps = 2/185 (1%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN-DTEQAVIYALEAGYTHIDTAYKYGI 256
VPTL+++ G P + LG W Q+++ DT +V A+E GY HIDTA YG
Sbjct: 8 VPTLEMNDGKTTPQLGLGVW----------QLSDEDTYTSVRAAIETGYRHIDTAAIYGN 57
Query: 257 EDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
E+ VGRA+ G ++RE +FITTKLWN+ ++ A +S + L ++YVDLYL+H
Sbjct: 58 EEAVGRAVADAVKAGDVQREELFITTKLWNA--DQACGKEAFAESQKKLGMDYVDLYLLH 115
Query: 434 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 613
WP ++ F+ + M + ++ G SIG+ NF E + + +G P+
Sbjct: 116 WPCPQADS--------FVQAYDSMAEIQQSGGATSIGVCNFYPEALDALKQAG-HTPAVN 166
Query: 614 QIELN 628
QIE++
Sbjct: 167 QIEIH 171
>UniRef50_A2QVE5 Cluster: Similarity: shows similarity to several
dehydrogenases of different specificities; n=4;
Pezizomycotina|Rep: Similarity: shows similarity to
several dehydrogenases of different specificities -
Aspergillus niger
Length = 381
Score = 105 bits (251), Expect = 1e-21
Identities = 67/194 (34%), Positives = 99/194 (51%), Gaps = 18/194 (9%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L+SG IP + GTW G+V AV AL+AGY H+D A Y + +V
Sbjct: 9 LNSGAQIPQLGFGTW--QSAPGQV-------GDAVYEALKAGYRHLDLATIYQNQREVAE 59
Query: 275 ALTKKFSE--GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
+ + + + GLKRE IFIT+KLWNS H+ V AL + L L L+Y+DLYL+HWP++
Sbjct: 60 GIKRAYKDVPGLKREDIFITSKLWNSQHDPAVVEKALDECLAELELDYLDLYLVHWPVSF 119
Query: 449 FENDTLL----------------DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI 580
L D++ +DTW+ M K +++G+SN ++ I
Sbjct: 120 TTGSELFPLVKDSSVEGGDVVINDDISIVDTWKAMTQLPK-SKARTVGVSNHMIPHLEAI 178
Query: 581 IDSGLEKPSALQIE 622
I++ P+ QIE
Sbjct: 179 INATGVVPAVNQIE 192
>UniRef50_Q8J0K1 Cluster: 4-dihydromethyltrisporate dehydrogenase;
n=2; Parasitella parasitica|Rep:
4-dihydromethyltrisporate dehydrogenase - Parasitella
parasitica
Length = 321
Score = 104 bits (250), Expect = 2e-21
Identities = 61/166 (36%), Positives = 91/166 (54%), Gaps = 17/166 (10%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 358
D E + A++ GY D A YG E +VGR + K EGL KRE +FI TKLWN++H +
Sbjct: 29 DAENTIYQAIKIGYRLFDGACDYGNEVEVGRGINKAIKEGLVKREELFIVTKLWNTFHSK 88
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL-----------DNVDF-----LD 490
+ V A + L++ LEY DLYLIH+PI + D + D ++F +
Sbjct: 89 QHVRTAFDRQLKDWGLEYFDLYLIHFPIPLQYVDPAVSYPPEWYVPHADKLNFERSPIHE 148
Query: 491 TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
W M + LT++IG++NFN + I ++ KP+ LQIE++
Sbjct: 149 CWAEMEKLVQAKLTRNIGVANFNCQAILDLLSYAKIKPAVLQIEIH 194
>UniRef50_Q8F1G4 Cluster: Aldehyde reductase; n=8; Bacteria|Rep:
Aldehyde reductase - Leptospira interrogans
Length = 278
Score = 104 bits (249), Expect = 2e-21
Identities = 62/181 (34%), Positives = 101/181 (55%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T+ L++G ++P++ LG W GK + ++AV+ ALEAGY HIDTA Y E
Sbjct: 11 TIMLNNGISMPILGLGVW--KTKSGK------ECKEAVLNALEAGYRHIDTARIYDNEVD 62
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VG+A+ + G+ R+ IFITTKLWN+ ++ AL SL+ L +++VDLYLIH+P+
Sbjct: 63 VGQAIRES---GIPRKEIFITTKLWNADQGSDKTRKALENSLDRLGIDFVDLYLIHFPVT 119
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 625
+D+W+ + L K+IG+SN+ + ++ + P+ Q+E
Sbjct: 120 SKR----------MDSWKELEKLYHDKLCKAIGVSNYTIIHLTELLKNSQITPAVNQVEF 169
Query: 626 N 628
+
Sbjct: 170 H 170
>UniRef50_A5VK30 Cluster: 2,5-didehydrogluconate reductase; n=2;
Lactobacillus reuteri|Rep: 2,5-didehydrogluconate
reductase - Lactobacillus reuteri F275
Length = 300
Score = 104 bits (249), Expect = 2e-21
Identities = 65/184 (35%), Positives = 102/184 (55%), Gaps = 2/184 (1%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P ++L++G IP + LG W K + + T+Q V A+ Y IDTA +YG E
Sbjct: 11 PKIKLNNGHLIPQLGLGVW-----KASLAE----TQQMVKEAIMNDYVLIDTAKQYGNEA 61
Query: 263 QVGRALTKKF-SEGLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHW 436
VG+ + F + G KR+SIF+TTK++N + +++ A+ + L+ L YVDL L+HW
Sbjct: 62 AVGQGIQDGFKATGRKRDSIFLTTKIFNGDQGDYDKLRQAVNEQLKKLQTNYVDLLLLHW 121
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P+ N + ++WR + D K G K+IG+ NFN E++ ++D KP+ Q
Sbjct: 122 PV----------NDKYNESWRALEDIYKDGQAKAIGVCNFNVERMTDLLDHAKIKPAINQ 171
Query: 617 IELN 628
IE N
Sbjct: 172 IEFN 175
>UniRef50_A3LTU8 Cluster: D-arabinose dehydrogenase; n=5;
Saccharomycetales|Rep: D-arabinose dehydrogenase -
Pichia stipitis (Yeast)
Length = 326
Score = 104 bits (249), Expect = 2e-21
Identities = 69/197 (35%), Positives = 109/197 (55%), Gaps = 21/197 (10%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
LS+G IP + LGT P ++ ++ VI A++AGY HIDTA+ YG E+ +G+
Sbjct: 12 LSNGKTIPALGLGTVPPEDP--------HELKEQVITAVKAGYRHIDTAWYYGTEEYIGQ 63
Query: 275 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 451
AL + F EG+ KRE +FITTK+W S+ + +L KSL +L L+YVDL+L HWP+ +
Sbjct: 64 ALKQLFEEGIVKREDLFITTKVWPSFWRNPE--KSLDKSLADLGLDYVDLFLQHWPVVLH 121
Query: 452 --EN----------------DTLLDNVDFLDTWRGMID-AKKLGLTKSIGISNFNQEQIQ 574
EN D + + ++D + + D KSIG+SN++ +++
Sbjct: 122 GDENGLPPQPRDKDGKLIYDDDPVSGIKYIDAYHSLEDIMDNTSKVKSIGVSNYSIPKLR 181
Query: 575 RIIDS-GLEKPSALQIE 622
+++ + KP QIE
Sbjct: 182 KLLAAVRKHKPVVNQIE 198
>UniRef50_Q8G7K9 Cluster: Dehydrogenase or reductase protein; n=4;
Bifidobacterium|Rep: Dehydrogenase or reductase protein
- Bifidobacterium longum
Length = 289
Score = 103 bits (247), Expect = 4e-21
Identities = 66/184 (35%), Positives = 98/184 (53%), Gaps = 1/184 (0%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VP + L G +IP V LG L +G V V + ALEAGY HID A Y E
Sbjct: 11 VPDIALKDGHSIPQVGLGV-LRIDDEGVVPVVES--------ALEAGYRHIDGAAGYNNE 61
Query: 260 DQVGRALTKK-FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
VGRAL +++G KRE++++TTKL +S + + A SL+ L L+YVD+Y+IHW
Sbjct: 62 AGVGRALAASGYNKGAKRETLWVTTKLRDSQQGYDSALKAFDNSLKLLQLDYVDMYMIHW 121
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P T DTW+ + + G+ +++G+ NF ++R+ + P+ Q
Sbjct: 122 PTPFDWRST--------DTWKAFVKLRDEGMARTLGVCNFMPADLKRLHEETGAWPAVNQ 173
Query: 617 IELN 628
IEL+
Sbjct: 174 IELH 177
>UniRef50_Q4Q5N9 Cluster: Prostaglandin f synthase, putative; n=7;
cellular organisms|Rep: Prostaglandin f synthase,
putative - Leishmania major
Length = 279
Score = 103 bits (247), Expect = 4e-21
Identities = 59/178 (33%), Positives = 95/178 (53%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
LS+G +P + +GTW + +VV + +A+ AGY H+DTA+ Y E VG+
Sbjct: 10 LSNGVQVPQLGIGTWEA-KDGNEVVNIK--------WAVNAGYRHVDTAHYYKNEKGVGQ 60
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 454
+++ G+ R IF+TTKLWN H E + A +S + L +EYVDLYLIHWP
Sbjct: 61 GISEC---GVPRSDIFVTTKLWNYDHGYESALAAFEQSRQALGVEYVDLYLIHWP----- 112
Query: 455 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
N +++TWR ++ ++IG+SNF + ++ + P Q+E++
Sbjct: 113 ----GPNRSYIETWRAFEKLYEMKKVRAIGVSNFEPHHLDDLLANCTVPPMVNQVEMH 166
>UniRef50_P38715 Cluster: NADPH-dependent aldose reductase GRE3;
n=39; cellular organisms|Rep: NADPH-dependent aldose
reductase GRE3 - Saccharomyces cerevisiae (Baker's
yeast)
Length = 327
Score = 103 bits (247), Expect = 4e-21
Identities = 73/197 (37%), Positives = 104/197 (52%), Gaps = 21/197 (10%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L++G +P+V LG W + KV + A++ GY D A YG E +VG
Sbjct: 7 LNNGLKMPLVGLGCW---KIDKKVCA------NQIYEAIKLGYRLFDGACDYGNEKEVGE 57
Query: 275 ALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM- 448
+ K SEGL R+ IF+ +KLWN++H + V AL+K+L ++ L+Y+DLY IH+PIA
Sbjct: 58 GIRKAISEGLVSRKDIFVVSKLWNNFHHPDHVKLALKKTLSDMGLDYLDLYYIHFPIAFK 117
Query: 449 ---FEND------TLLD----------NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 571
FE T D +V +DT+R + + GL KSIG+SNF I
Sbjct: 118 YVPFEEKYPPGFYTGADDEKKGHITEAHVPIIDTYRALEECVDEGLIKSIGVSNFQGSLI 177
Query: 572 QRIIDSGLEKPSALQIE 622
Q ++ KP ALQIE
Sbjct: 178 QDLLRGCRIKPVALQIE 194
>UniRef50_Q7PM68 Cluster: ENSANGP00000014386; n=1; Anopheles gambiae
str. PEST|Rep: ENSANGP00000014386 - Anopheles gambiae
str. PEST
Length = 310
Score = 103 bits (246), Expect = 5e-21
Identities = 59/162 (36%), Positives = 90/162 (55%), Gaps = 12/162 (7%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE--GLKRESIFITTKLWNSYHE 355
D ++A+ A++ GY DTA YG E VG A+ +K E L R+ FI +KL SYH
Sbjct: 31 DGKEAIRTAIDVGYRMFDTAVAYGNEAIVGEAIREKIRECNNLTRDDFFIISKLSGSYHR 90
Query: 356 REQVIPALRKSLENLNLEYVDLYLIHWPIAM------FENDTLLDNVDF----LDTWRGM 505
++ V R +L+ L ++YVDLYL+H P+A+ N T L+ +D + W G+
Sbjct: 91 QDLVEKCCRMTLDRLGMDYVDLYLMHTPVALQSEKKCARNGTKLNAIDDSIAPTEAWIGL 150
Query: 506 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNL 631
+ GL +SIG+SNFN+ QI ++ P+ QIE ++
Sbjct: 151 EQCYQEGLCRSIGVSNFNEHQINALLSDASIVPAVNQIECSI 192
>UniRef50_A0AWM8 Cluster: Aldo/keto reductase; n=4;
Actinomycetales|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 287
Score = 102 bits (245), Expect = 6e-21
Identities = 58/183 (31%), Positives = 99/183 (54%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+P L+L G IP + LGTW + ++ E AV +AL++GY +DTA++Y E
Sbjct: 13 IPRLKLPHGHTIPRLGLGTW---------PMLEDECETAVRFALQSGYRLVDTAFQYRNE 63
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+ VGR + + G+ R +FI++K H + V A +SL L L+++D+++ HWP
Sbjct: 64 EAVGRGIR---TAGVPRSELFISSKFNKESHSIDGVQRAYDESLRKLGLDHLDMFMCHWP 120
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
+ ++D W+G++ + G K+IG+SNF ++ IID+ P QI
Sbjct: 121 VPALGK--------YVDAWKGLVKLLEEGRVKAIGVSNFKPAHLKDIIDATGVVPDVNQI 172
Query: 620 ELN 628
+L+
Sbjct: 173 QLS 175
>UniRef50_P47137 Cluster: Probable oxidoreductase YJR096W; n=8;
Saccharomycetales|Rep: Probable oxidoreductase YJR096W -
Saccharomyces cerevisiae (Baker's yeast)
Length = 282
Score = 102 bits (244), Expect = 8e-21
Identities = 69/185 (37%), Positives = 103/185 (55%), Gaps = 6/185 (3%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
+LS+G IP +ALGT+ P+ + ++ V ++ GY H DTA YG E +VG
Sbjct: 7 KLSNGFKIPSIALGTY--DIPRSQTAEI-------VYEGVKCGYRHFDTAVLYGNEKEVG 57
Query: 272 RALTKKFSE---GLKRESIFITTKLWNSYHEREQVIPALRKSLENLN-LEYVDLYLIHWP 439
+ K +E KRE IF TTKLWNS + ++ A+R+ L ++ L+Y+DL LIH P
Sbjct: 58 DGIIKWLNEDPGNHKREEIFYTTKLWNSQNGYKRAKAAIRQCLNEVSGLQYIDLLLIHSP 117
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEKPSAL 613
+ E L L+TWR M +A GL KSIG+SN+ ++ I +++ KP
Sbjct: 118 L---EGSKLR-----LETWRAMQEAVDEGLVKSIGVSNYGKKHIDELLNWPELKHKPVVN 169
Query: 614 QIELN 628
QIE++
Sbjct: 170 QIEIS 174
>UniRef50_UPI0000499B0E Cluster: oxidoreductase, aldo/keto reductase
family; n=1; Entamoeba histolytica HM-1:IMSS|Rep:
oxidoreductase, aldo/keto reductase family - Entamoeba
histolytica HM-1:IMSS
Length = 307
Score = 101 bits (243), Expect = 1e-20
Identities = 66/186 (35%), Positives = 99/186 (53%), Gaps = 7/186 (3%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L++G +P + LGTWL + +AV ALE GY ID A Y E ++G
Sbjct: 8 LNNGKFMPAIGLGTWLA---------APGEVGKAVTLALENGYRLIDCARFYKNEKEIGE 58
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF- 451
+ F + RE +F+T+KLW R + + +S+++L +Y+DLYLIHWPIA+
Sbjct: 59 MGIEPFLKNHPREELFVTSKLWMDQVTR--IRESCLESIQDLKCKYLDLYLIHWPIALKV 116
Query: 452 ------ENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 613
+ + LD +D + W+ M GL KSIG+SNF QI++I+ KP
Sbjct: 117 DASNPPKPEDFLD-MDITEIWQEMERLVDEGLVKSIGLSNFTIPQIEKIMKMCRIKPVIN 175
Query: 614 QIELNL 631
Q+ELN+
Sbjct: 176 QVELNV 181
>UniRef50_Q235V6 Cluster: Oxidoreductase, aldo/keto reductase family
protein; n=2; Tetrahymena thermophila SB210|Rep:
Oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 332
Score = 101 bits (243), Expect = 1e-20
Identities = 60/181 (33%), Positives = 105/181 (58%), Gaps = 1/181 (0%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
+L++G +P+V LGT+L + + ++TN + AL+AGY HIDTA Y E +G
Sbjct: 9 KLNNGQIMPLVGLGTYLLNSKE----EMTN----LLRTALDAGYRHIDTAVNYQNEAMIG 60
Query: 272 RALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
+L F EG R+ +FI +K++ + + ++ +++KSL+ L L+YVDLY +H+P+
Sbjct: 61 ESLKTIFKEGKYSRKDLFIVSKVFPN--KGINMLESVKKSLKELQLDYVDLYYLHFPLGF 118
Query: 449 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
++ W + +A +LGL KSIG+SNFN + ++ KP + Q+E++
Sbjct: 119 LSEKEEFVHLPVHVAWAQLEEAHRLGLAKSIGVSNFNVMALADLLSYAKVKPVSNQVEVS 178
Query: 629 L 631
+
Sbjct: 179 V 179
>UniRef50_Q9X0A2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=21; Bacteria|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 286
Score = 101 bits (242), Expect = 1e-20
Identities = 66/184 (35%), Positives = 98/184 (53%), Gaps = 1/184 (0%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VP + L++G +P++ G + P K TE+ V A++ GY IDTA Y E
Sbjct: 3 VPKVTLNNGVEMPILGYGVF--QIPPEK-------TEECVYEAIKVGYRLIDTAASYMNE 53
Query: 260 DQVGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
+ VGRA+ + EG+ +RE +F+TTKLW S E A KSL+ L LEY+DLYLIH
Sbjct: 54 EGVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQ 113
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P D W+ M + K GL ++IG+SNF +++ ++ P+ Q
Sbjct: 114 PFG-----------DVHCAWKAMEEMYKDGLVRAIGVSNFYPDRLMDLMVHHEIVPAVNQ 162
Query: 617 IELN 628
IE++
Sbjct: 163 IEIH 166
>UniRef50_Q7VG53 Cluster: Aldo-keto reductase; n=28; Bacteria|Rep:
Aldo-keto reductase - Helicobacter hepaticus
Length = 292
Score = 101 bits (242), Expect = 1e-20
Identities = 66/178 (37%), Positives = 99/178 (55%), Gaps = 3/178 (1%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L++G IP + LGTW R VV E AV A + GY HIDTA YG E VG
Sbjct: 17 LNNGNKIPKLGLGTW---RIDDNVV------EAAVREAFKVGYRHIDTAQAYGNERGVGE 67
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP---IA 445
A+ K +KRE +FIT+K+ Y + + ++ SL+ + L+++DL LIH P +
Sbjct: 68 AVRKS---KIKREELFITSKIRAEYKDYKSASASIDTSLKTMKLDFIDLMLIHSPQPWNS 124
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
+ D +NV + + + DA+K G +SIG+SNF Q+ ++ I+ + KP+A QI
Sbjct: 125 FRKGDYFKENV---EVYNALEDAQKAGKVRSIGVSNFLQKDLENILKNCKTKPAANQI 179
>UniRef50_UPI0000DB6EE9 Cluster: PREDICTED: similar to C35D10.6;
n=2; Endopterygota|Rep: PREDICTED: similar to C35D10.6 -
Apis mellifera
Length = 292
Score = 101 bits (241), Expect = 2e-20
Identities = 66/188 (35%), Positives = 102/188 (54%), Gaps = 4/188 (2%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
IV + LSSG ++P++ GT+ +Q Q V +L G+ IDTA Y
Sbjct: 4 IVRNVCLSSGYDMPLIGFGTYK--------IQGRELVYQVVDESLNVGFRSIDTAVGYRN 55
Query: 257 EDQVGRALTKKFSE-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLI 430
E+ +G AL + L+R IFITTKL S + + + + ++KSL+ N Y+DLYLI
Sbjct: 56 EEDIGYALKNLLPKYNLQRSDIFITTKLPPSVNGDPKGIEQCVQKSLKAFNTTYIDLYLI 115
Query: 431 HWPIAMFENDTLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-KP 604
HWP A +T +N TW ++D KK G +SIG+SNF + +Q ++ + + P
Sbjct: 116 HWPGATRIPETSTNNPSLRAKTWNKLVDLKKQGFIRSIGVSNFTIKHLQELLQNCKDILP 175
Query: 605 SALQIELN 628
+ Q+EL+
Sbjct: 176 AVNQVELH 183
>UniRef50_UPI00006CCCD7 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 323
Score = 101 bits (241), Expect = 2e-20
Identities = 59/185 (31%), Positives = 105/185 (56%), Gaps = 6/185 (3%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQ 265
+QL++G +P++ LGT +P V +VT + ++ AL+ GY + DTA +Y E +
Sbjct: 15 VQLNNGYKMPLLGLGT----QPYDIVTRVTVEEMTTLLSNALDFGYRNFDTAKQYRNEVE 70
Query: 266 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP- 439
+G+A F +G KRE +FITTKL+ + +++ ++ SL+ L Y+DLYLI W
Sbjct: 71 IGQAFQNIFQQGKYKREDVFITTKLF-PFKIEKKIKEVVQNSLDQLQTSYIDLYLIQWSF 129
Query: 440 ---IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 610
+ F+ +++ + WR + + +LG+ +SIG++NFN + + ++ KP
Sbjct: 130 TPVLTNFDGSVAVNHRPIHEVWRELEECVELGMIRSIGVANFNCQMVLDLLSYAKIKPVV 189
Query: 611 LQIEL 625
QIE+
Sbjct: 190 NQIEV 194
>UniRef50_A2UAH0 Cluster: Aldo/keto reductase; n=1; Bacillus
coagulans 36D1|Rep: Aldo/keto reductase - Bacillus
coagulans 36D1
Length = 273
Score = 101 bits (241), Expect = 2e-20
Identities = 61/180 (33%), Positives = 96/180 (53%), Gaps = 2/180 (1%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T L +G IP + LGTW P G+ T AV +AL+ GY HIDTAY Y E+
Sbjct: 7 TFVLENGVAIPKIGLGTW--QVPNGET------TYHAVSFALKNGYRHIDTAYAYHNEES 58
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH--WP 439
VG+A+ G+ R IF+T+KL ++ + +++ N LE +DLYLIH WP
Sbjct: 59 VGKAVR---DSGIDRRDIFVTSKLPAEIKSYDKALKTFDETMGNFGLEQLDLYLIHAPWP 115
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
+ D +N+ + W+ M + + G ++IG+SNF+ ++ ++++ KP QI
Sbjct: 116 WSEKGADYTKENI---EVWKAMEEIYESGRCRAIGVSNFSVSDLKAVMENAKIKPMVNQI 172
>UniRef50_UPI00006CD296 Cluster: oxidoreductase, aldo/keto reductase
family protein; n=1; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 295
Score = 100 bits (240), Expect = 3e-20
Identities = 64/183 (34%), Positives = 99/183 (54%), Gaps = 1/183 (0%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T +L +G +PV LGT+ KVV + + AL+ GY HIDTA Y E Q
Sbjct: 7 TTELCNGSKLPVFGLGTY-------KVVS-KEEMVTFLRTALDLGYRHIDTAIMYENEKQ 58
Query: 266 VGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
+G AL + + EG KRE +F+ TKL+++ + +V +R+SL+NL Y+DLYL+H+
Sbjct: 59 IGDALQEIYKEGKYKREDLFLVTKLFSN--KNTKVEDQVRQSLQNLQTNYIDLYLLHYAS 116
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
+ + L + W + + GL ++IGISNFN + + + KP QIE
Sbjct: 117 SPPTDQFELTHKPVFQVWAEFEELVQKGLIRNIGISNFNVQMLLDLYSYCKIKPVVNQIE 176
Query: 623 LNL 631
+N+
Sbjct: 177 VNV 179
>UniRef50_Q1IN88 Cluster: Aldehyde reductase; n=5; Bacteria|Rep:
Aldehyde reductase - Acidobacteria bacterium (strain
Ellin345)
Length = 313
Score = 100 bits (240), Expect = 3e-20
Identities = 62/184 (33%), Positives = 98/184 (53%), Gaps = 12/184 (6%)
Frame = +2
Query: 107 GNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTK 286
G+IP + GT + + T D AL AG+ H D A +Y E +VG AL
Sbjct: 18 GHIPALGFGTLIAD--PALTITATRD-------ALAAGFRHFDCAERYRNEREVGEALRA 68
Query: 287 KFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM----- 448
+ G + RE IF+TTKLWN+ H E+V PA SL+ L L+Y+DLYLIH P A
Sbjct: 69 GRAAGNIAREEIFVTTKLWNTNHRPERVEPAFEASLDRLGLDYLDLYLIHTPFAFQPGDE 128
Query: 449 ----FENDTLL--DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 610
+N +++ + V +TW + + G ++IG+S+ + +++ I ++ KP+
Sbjct: 129 QDPRDQNGSVIYDEGVTLRETWSALENLVDRGRCRAIGLSDISMDRLAPIYEAARIKPAV 188
Query: 611 LQIE 622
+Q+E
Sbjct: 189 VQVE 192
>UniRef50_P70883 Cluster: AkrI; n=1; Butyrivibrio fibrisolvens|Rep:
AkrI - Butyrivibrio fibrisolvens
Length = 172
Score = 100 bits (240), Expect = 3e-20
Identities = 58/173 (33%), Positives = 92/173 (53%), Gaps = 1/173 (0%)
Frame = +2
Query: 71 ELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 250
E + ++L++G IP+ GT+ ++ N+ +V AL+ GY HIDTA Y
Sbjct: 2 ESLTTRIKLNNGTAIPMFGYGTYK--------IKDQNEAYNSVRLALKNGYRHIDTAAFY 53
Query: 251 GIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL 427
E V A+ E KRE IF+T+K W + ++ + A K++ + ++Y+DLYL
Sbjct: 54 ENEKFVANAIKDFMEESQTKREDIFVTSKAWKTELGYDKTLAAFEKTMNEMQMDYLDLYL 113
Query: 428 IHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
+HWP A + D +N + TW+ M + K G K+IG+SNF + IID
Sbjct: 114 VHWP-ASYAFDDDWENTN-RQTWKAMTEIYKSGRVKAIGVSNFLTHHLDTIID 164
>UniRef50_Q5T2L2 Cluster: Aldo-keto reductase family 1 member C-like
protein 1; n=14; Eutheria|Rep: Aldo-keto reductase
family 1 member C-like protein 1 - Homo sapiens (Human)
Length = 302
Score = 100 bits (240), Expect = 3e-20
Identities = 58/161 (36%), Positives = 92/161 (57%), Gaps = 13/161 (8%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWL-GHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
+++L+ G +PV+ GT+ H PK + + T A++ G+ HID+AY Y E+
Sbjct: 10 SVRLNDGPFMPVLGFGTYAPDHTPKSQAAEATK-------VAIDVGFRHIDSAYLYQNEE 62
Query: 263 QVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+VG+A+ +K ++G +KRE IF T KLW ++ E V PAL +SL+ L +YVDL++IH P
Sbjct: 63 EVGQAIWEKIADGTVKREEIFYTIKLWATFFRAELVHPALERSLKKLGPDYVDLFIIHVP 122
Query: 440 IAMFE-----------NDTLLDNVDFLDTWRGMIDAKKLGL 529
AM + + +L+ V+ DTW + K GL
Sbjct: 123 FAMKQPGKELLPKDASGEIILETVELCDTWELELILNKPGL 163
>UniRef50_Q5BLA6 Cluster: Zgc:110782; n=2; Danio rerio|Rep:
Zgc:110782 - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 287
Score = 99 bits (238), Expect = 4e-20
Identities = 66/185 (35%), Positives = 101/185 (54%), Gaps = 2/185 (1%)
Frame = +2
Query: 74 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYG 253
+IVP+++L SG +P++ LGT+ +Q +Q+V AL+AGY DTA YG
Sbjct: 1 MIVPSVRLMSGTQMPLLGLGTYK--------LQDHEQLKQSVSCALQAGYRAFDTAAVYG 52
Query: 254 IEDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 430
E +G+ L + + GL RE +FI +KL S H LR SLE L+ EY+DLYLI
Sbjct: 53 NEAHLGQVLKELLPKYGLIREDVFIISKLAPSDHGLRAKEGCLR-SLEQLDCEYIDLYLI 111
Query: 431 HWP-IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 607
HWP + + + + +W + + G K+IG+SN+ + I+ ++ S P+
Sbjct: 112 HWPGMEGLDPEDSRHSEYRAQSWATLEEFHASGQFKAIGVSNYTAKHIRELLASCRVPPA 171
Query: 608 ALQIE 622
LQIE
Sbjct: 172 VLQIE 176
>UniRef50_Q6NII7 Cluster: Putative oxidoreductase; n=2;
Corynebacterium|Rep: Putative oxidoreductase -
Corynebacterium diphtheriae
Length = 290
Score = 99.5 bits (237), Expect = 6e-20
Identities = 59/187 (31%), Positives = 102/187 (54%), Gaps = 1/187 (0%)
Frame = +2
Query: 71 ELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 250
E I+PT+ L+ G +P + GT+ K+ + D +AV A+E GY HIDTA Y
Sbjct: 8 ENIIPTITLNDGTEMPAIGFGTY-------KLRE--QDAYRAVRSAIEVGYRHIDTASLY 58
Query: 251 GIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYL 427
E++VGRA+ + G + R+ +FITTK+WN H + + ++SL L L+Y+D +
Sbjct: 59 KNEEEVGRAVADAITAGEVARDELFITTKVWNDMHGDQLTQRSFQESLHRLGLDYIDCCM 118
Query: 428 IHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPS 607
+HWP + L +++++ + + LG +S+ ++NF E ++ I+ P
Sbjct: 119 VHWP---WPQKGL-----YVESFAALAKIQGLGQLQSVAVANFYPEVLREIVAETGIAPV 170
Query: 608 ALQIELN 628
Q+EL+
Sbjct: 171 LNQVELH 177
>UniRef50_Q0SFM4 Cluster: Probable 2,5-didehydrogluconate reductase;
n=1; Rhodococcus sp. RHA1|Rep: Probable
2,5-didehydrogluconate reductase - Rhodococcus sp.
(strain RHA1)
Length = 265
Score = 99.5 bits (237), Expect = 6e-20
Identities = 60/173 (34%), Positives = 94/173 (54%)
Frame = +2
Query: 110 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 289
+IP + LGTW P D +AV+ +EAGY IDTA Y ED VG AL +
Sbjct: 3 DIPPLGLGTWPLTGP---------DATRAVLSGIEAGYRLIDTATIYDNEDAVGVALAEC 53
Query: 290 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 469
G+ RE +F+TTKL S H + A+ +SL+NL L+ +DL+LIHWP+
Sbjct: 54 ---GVPREELFVTTKLRGSDHVSGDIRGAVERSLKNLGLDRLDLFLIHWPLPRHNR---- 106
Query: 470 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
++ + M+ + GL + +G+SNF + ++R++ E P+ QI+++
Sbjct: 107 ----YVAAFEAMLACRDAGLVRHVGVSNFLETHLRRVVAETGESPAVNQIQMD 155
>UniRef50_Q9P6D3 Cluster: Related to aldo-keto reductase YPR1; n=10;
Pezizomycotina|Rep: Related to aldo-keto reductase YPR1
- Neurospora crassa
Length = 322
Score = 99.5 bits (237), Expect = 6e-20
Identities = 67/186 (36%), Positives = 96/186 (51%), Gaps = 4/186 (2%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQ-VTNDTEQAVIYALEAGYTHIDTAYKYG 253
++P+L+LS G IP++ G + G ++ A + AL AGY H+D A YG
Sbjct: 23 LIPSLKLSDGNEIPMLGYGLGTANYKSGDSADTISEPIVNATLTALNAGYAHLDGAEVYG 82
Query: 254 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
E ++GRA+ + L R S++ITTK + V + +SLE L L+YVDLYL+H
Sbjct: 83 NEVELGRAIAQ---SKLPRSSLYITTK--TIVRAGDTVTQSFNRSLEKLGLDYVDLYLLH 137
Query: 434 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEKPS 607
P +N L WR M K G+ KSIG+SNF +Q + D GL+ P
Sbjct: 138 SPF-FAKNPEQLQ-----AAWREMEKIKDSGMAKSIGVSNFLISHLQTLFDIPGGLQYPP 191
Query: 608 AL-QIE 622
+ QIE
Sbjct: 192 VVNQIE 197
>UniRef50_Q76L37 Cluster: Conjugated polyketone reductase C1; n=3;
Saccharomycetales|Rep: Conjugated polyketone reductase
C1 - Candida parapsilosis (Yeast)
Length = 304
Score = 99.5 bits (237), Expect = 6e-20
Identities = 69/191 (36%), Positives = 103/191 (53%), Gaps = 12/191 (6%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVI----YALEAGYTHIDTAYKYGIE 259
+LS+G IP VA GT + +G ND ++ +I AL +G+ HID A YG
Sbjct: 9 KLSNGNKIPAVAFGTGTKYFKRGH-----NDLDKQLIGTLELALRSGFRHIDGAEIYGTN 63
Query: 260 DQVGRALTKKFSEGLKRESIFITTKL------WNSYHEREQ-VIPALRKSLENLNLEYVD 418
++G AL + GL R+ +FIT K ++ H + Q AL+ LE+L LEYVD
Sbjct: 64 KEIGIALK---NVGLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVD 120
Query: 419 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 598
LYLIH+P ++ D ++ WR + AK GL ++IG+SNF E ++ I+D+ +
Sbjct: 121 LYLIHFPYISEKSH----GFDLVEAWRYLERAKNEGLARNIGVSNFTIENLKSILDANTD 176
Query: 599 K-PSALQIELN 628
P QIE +
Sbjct: 177 SIPVVNQIEFS 187
>UniRef50_Q8ZH36 Cluster: 2,5-diketo-D-gluconic acid reductase B;
n=91; Proteobacteria|Rep: 2,5-diketo-D-gluconic acid
reductase B - Yersinia pestis
Length = 267
Score = 99.1 bits (236), Expect = 8e-20
Identities = 66/174 (37%), Positives = 102/174 (58%), Gaps = 1/174 (0%)
Frame = +2
Query: 110 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 289
+IPV LGT+ R + ++V +V AL GY IDTA Y E VG+A+ +
Sbjct: 2 SIPVFGLGTF---RLQDQIVI------DSVSQALTLGYRAIDTAQIYENEAPVGQAIQES 52
Query: 290 FSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLL 469
G+ R+ +FITTK+W + ++++IP+LR+S++ L +YVDL LIHWP +
Sbjct: 53 ---GINRDELFITTKIWIANLSKDKLIPSLRESIQKLKTDYVDLTLIHWP-------SPN 102
Query: 470 DNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDS-GLEKPSALQIELN 628
D V + ++ AK LGLT+ IGISNF + +++ I + G E+ + QIEL+
Sbjct: 103 DEVSVAEFMSELLKAKGLGLTRQIGISNFTIDLMKQAIAAVGAEEIATNQIELS 156
>UniRef50_Q6U5V3 Cluster: Putative uncharacterized protein; n=1;
Klebsiella pneumoniae|Rep: Putative uncharacterized
protein - Klebsiella pneumoniae
Length = 279
Score = 98.7 bits (235), Expect = 1e-19
Identities = 55/149 (36%), Positives = 90/149 (60%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 361
D + + AL+AG+ H DTA Y ED VGRAL +++E + RE +FIT+K+
Sbjct: 28 DVDSLIRQALKAGFRHFDTAQAYFNEDGVGRAL--RYTE-VPREQLFITSKIRGRDMGYA 84
Query: 362 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 541
+ + + ++LE L +EY++L+LIHWPI N+ +++TW I+ + GL +SI
Sbjct: 85 RTLVSFNETLERLGVEYLELFLIHWPIP-------AKNL-YVETWEASIELEASGLIRSI 136
Query: 542 GISNFNQEQIQRIIDSGLEKPSALQIELN 628
G+SNF + I+R+I+ P+ Q+EL+
Sbjct: 137 GVSNFTCQHIERLIEDTGVVPAVNQLELH 165
>UniRef50_Q05KR9 Cluster: Benzil reductase; n=5; Bacillales|Rep:
Benzil reductase - Bacillus subtilis
Length = 276
Score = 98.7 bits (235), Expect = 1e-19
Identities = 61/181 (33%), Positives = 93/181 (51%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T++L +G +P LG + V+ N+ ++V A++ GY IDTA Y E+
Sbjct: 8 TVKLHNGVEMPWFGLGVFK--------VENGNEATESVKAAIKNGYRSIDTAAIYKNEEG 59
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VG + + G+ RE +FIT+K+WN E + A KSLE L L+Y+DLYLIHWP
Sbjct: 60 VGIGIKES---GVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP-- 114
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 625
+ DTWR + K G ++IG+SNF ++ ++ KP Q+E
Sbjct: 115 --------GKDKYKDTWRALEKLYKDGKIRAIGVSNFQVHHLEELLKDAEIKPMVNQVEF 166
Query: 626 N 628
+
Sbjct: 167 H 167
>UniRef50_UPI0000D9A956 Cluster: PREDICTED: similar to aldo-keto
reductase family 1, member B10, partial; n=1; Macaca
mulatta|Rep: PREDICTED: similar to aldo-keto reductase
family 1, member B10, partial - Macaca mulatta
Length = 275
Score = 98.3 bits (234), Expect = 1e-19
Identities = 61/154 (39%), Positives = 89/154 (57%), Gaps = 9/154 (5%)
Frame = +2
Query: 188 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE-GLKRESIFITTK------LWNS 346
++AV A++AGY HID AY Y E +VG A+ +K E +KRE +FI +K LW +
Sbjct: 49 KEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQEKIQEQAVKREDLFIVSKVHMAHWLWTT 108
Query: 347 YHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLG 526
+ ER V A K+L++L L Y+D+YLIHWP + L+D G
Sbjct: 109 FFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKAMEELVDE----------------G 152
Query: 527 LTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIE 622
L K++GISNFN QI+++++ GL+ KP Q+E
Sbjct: 153 LVKALGISNFNHFQIEKLLNKPGLKYKPVTNQVE 186
>UniRef50_Q88TV9 Cluster: Oxidoreductase; n=4; Lactobacillus|Rep:
Oxidoreductase - Lactobacillus plantarum
Length = 288
Score = 98.3 bits (234), Expect = 1e-19
Identities = 66/184 (35%), Positives = 93/184 (50%), Gaps = 2/184 (1%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND--TEQAVIYALEAGYTHIDTAYKYGI 256
PT+ L+ G IP + GT+ Q+ +D T QAV AL GY HIDTA Y
Sbjct: 5 PTITLNDGRAIPAIGFGTF----------QIPDDGSTYQAVKEALVIGYRHIDTAVAYFN 54
Query: 257 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
ED+VG+A+ G+ R+ I++T+KLW + + A+ +SL L L+Y+DLYLIH
Sbjct: 55 EDEVGQAIK---DSGIPRDQIWVTSKLWLQDYGFDAASRAIDRSLTKLRLDYIDLYLIHQ 111
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P D W+ M A+K G KSIG+SN Q+ + P+ Q
Sbjct: 112 PYG-----------DVPGAWQAMEAAQKAGKLKSIGVSNMTPTLWQKFVPQFETIPAVNQ 160
Query: 617 IELN 628
+E N
Sbjct: 161 VEFN 164
>UniRef50_Q043M4 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=2; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus gasseri (strain ATCC 33323 / DSM 20243)
Length = 273
Score = 98.3 bits (234), Expect = 1e-19
Identities = 61/151 (40%), Positives = 83/151 (54%)
Frame = +2
Query: 179 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 358
+ T+QAV+ A E GY IDTA Y E QVG A+ + GL R+ +FITTK +E
Sbjct: 25 DQTKQAVLSAFEEGYRLIDTAQYYQNEQQVGEAVK---ASGLNRDEVFITTKTMTDGYED 81
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 538
++ L +SL + L+Y DL LIHWP+ +D +DTW + A K G T++
Sbjct: 82 TKI--GLDESLRRIGLDYFDLVLIHWPMG---HD--------IDTWHALEAAYKAGKTRA 128
Query: 539 IGISNFNQEQIQRIIDSGLEKPSALQIELNL 631
IGISNFN Q +I +P QIE +L
Sbjct: 129 IGISNFNSRQTLDLIHQSSVRPMVDQIETHL 159
>UniRef50_A3JU52 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=1; Rhodobacterales bacterium HTCC2150|Rep:
2,5-diketo-D-gluconic acid reductase A - Rhodobacterales
bacterium HTCC2150
Length = 334
Score = 97.9 bits (233), Expect = 2e-19
Identities = 67/190 (35%), Positives = 98/190 (51%), Gaps = 9/190 (4%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYA-LEAGYTHIDTAYKYGIED 262
T L++ IP V GT+L ++ND ++ I A ++AGY HIDTA Y E
Sbjct: 39 TFTLNTTTTIPAVGFGTYL----------ISNDDAKSTISAAIQAGYRHIDTASGYQNEK 88
Query: 263 QVGRALTKKF-SEGLKRESIFITTKLW-------NSYHEREQVIPALRKSLENLNLEYVD 418
VG + S G+ R+ +F+T KLW ++ + Q + SL L L+YVD
Sbjct: 89 TVGAGIKAGLQSAGITRKDLFVTAKLWPGNPAWGDAPKTKAQTLDECDASLARLGLDYVD 148
Query: 419 LYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 598
LYLIH P + D L+ WR +++ + G +SIG+SNFN+ + I +GL
Sbjct: 149 LYLIHAP---YGGDMRLEQ------WRALLELQANGKARSIGVSNFNESHLNEIKAAGLP 199
Query: 599 KPSALQIELN 628
P A QIEL+
Sbjct: 200 MPDANQIELH 209
>UniRef50_Q5K8C5 Cluster: Aldo-keto reductase, putative; n=1;
Filobasidiella neoformans|Rep: Aldo-keto reductase,
putative - Cryptococcus neoformans (Filobasidiella
neoformans)
Length = 303
Score = 97.9 bits (233), Expect = 2e-19
Identities = 59/150 (39%), Positives = 84/150 (56%), Gaps = 1/150 (0%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHER 358
+T V +ALEAGY H+DTA Y E G+A+ + G RE IF+T+KL N+
Sbjct: 55 ETYDCVKWALEAGYRHVDTAEWYENEAPCGKAIADFLKATGTSREEIFLTSKLKNN-SSY 113
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 538
EQ L+ SL+ +EY DLYL+H I + NV W+ + DA+ GL KS
Sbjct: 114 EQAFVDLKGSLKRSGVEYFDLYLMHSAIG---GPVIRKNV-----WKALCDAQSQGLVKS 165
Query: 539 IGISNFNQEQIQRIIDSGLEKPSALQIELN 628
IG+SNF ++ IQ ID + P+ Q++L+
Sbjct: 166 IGVSNFGKKHIQEFIDQKVPLPTVNQVDLH 195
>UniRef50_Q0CK00 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 292
Score = 97.9 bits (233), Expect = 2e-19
Identities = 62/180 (34%), Positives = 92/180 (51%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P L L G +P++ GT + + + ALE G+ HID A YG E
Sbjct: 4 PALSLKDGNLVPILGFGTGTAWYKDDPNDPTNPELIEVLKAALEKGFHHIDAADSYGTER 63
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
+VG A+ + G+ RE +FITTK+ + + V AL SLE L L+YVDLYL+H P
Sbjct: 64 EVGIAIRES---GIPREQLFITTKVLEGWKD---VPGALDASLERLQLDYVDLYLLHNPY 117
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
+ N T D W+G+ K G +SIG+SNF + ++ I+++ P+ Q+E
Sbjct: 118 VI-PNLT-----DIQSAWKGLEAVKATGKARSIGVSNFQRNHLEAILETCSVVPAINQLE 171
>UniRef50_Q1Q8W8 Cluster: Aldo/keto reductase; n=1; Psychrobacter
cryohalolentis K5|Rep: Aldo/keto reductase -
Psychrobacter cryohalolentis (strain K5)
Length = 282
Score = 97.5 bits (232), Expect = 2e-19
Identities = 59/159 (37%), Positives = 90/159 (56%), Gaps = 2/159 (1%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
++ + NIPV+ LGTW + G+ D V L GY HIDTA YG E +V
Sbjct: 8 IRTAGQANIPVLGLGTW---QSTGQ------DCIDVVSQGLRMGYEHIDTAQAYGNEVEV 58
Query: 269 GRALTKKFSEGLKRESIFITTKLW--NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
G+ + + G+ R+ F+TTK++ + E E+++ A ++SLENL+ +YVDL L+HWP
Sbjct: 59 GKGIKQS---GVARDKFFLTTKIFPDDMKFEPEKLVAAAKRSLENLDTDYVDLLLLHWPD 115
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFN 559
D V +T + + +K GLT++IG+SNFN
Sbjct: 116 ---------DRVPLSETIPALCELQKQGLTRNIGVSNFN 145
>UniRef50_A0JX62 Cluster: 2,5-didehydrogluconate reductase; n=9;
Bacteria|Rep: 2,5-didehydrogluconate reductase -
Arthrobacter sp. (strain FB24)
Length = 291
Score = 97.5 bits (232), Expect = 2e-19
Identities = 58/163 (35%), Positives = 85/163 (52%), Gaps = 14/163 (8%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL--------------TKKFSEGLKRESI 319
D V ALEAGY H DTA YG E VG+A+ + + + L RE +
Sbjct: 29 DAAGLVTMALEAGYRHFDTAAMYGNETGVGKAIGALAGFAGGGPAGGSGEAAPSLSREDL 88
Query: 320 FITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWR 499
F+TTK+WN H + + A S+ NL +EYVDLYLIHWP A F +++R
Sbjct: 89 FVTTKVWNDDHGYDATMRAFDTSMSNLGMEYVDLYLIHWPCAR--------RGLFTESYR 140
Query: 500 GMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
M + G ++IG+SNF ++ ++++ P+ QIEL+
Sbjct: 141 AMETLYREGRIRAIGVSNFQPAHLEHLLETAEVVPAVNQIELH 183
>UniRef50_Q572D2 Cluster: Aldo-keto reductase, putative; n=1;
Phytophthora infestans|Rep: Aldo-keto reductase,
putative - Phytophthora infestans (Potato late blight
fungus)
Length = 255
Score = 97.5 bits (232), Expect = 2e-19
Identities = 62/183 (33%), Positives = 96/183 (52%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VPT L SG IP++ LG + + +T A++ +L+ GY HIDTA YG E
Sbjct: 5 VPTKILPSGARIPMIGLGVYQS--------EPGPETYNAILTSLKLGYRHIDTAEIYGNE 56
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+ VGRA+ G+ RE IF+TTKL+ + + + A + S + L + Y+ LYL+H P
Sbjct: 57 EDVGRAVR---DSGIPREEIFVTTKLFTTNWGYSKALAAGKASNDRLGIVYIYLYLLHAP 113
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
E DTWR + D ++ + IG+SNFN+ + + + KP+ Q+
Sbjct: 114 GPPKER---------ADTWRAVEDLREQETLRDIGVSNFNETLLATLRKTAHIKPAVNQV 164
Query: 620 ELN 628
EL+
Sbjct: 165 ELH 167
>UniRef50_A2QL02 Cluster: Putative frameshift; n=1; Aspergillus
niger|Rep: Putative frameshift - Aspergillus niger
Length = 357
Score = 97.5 bits (232), Expect = 2e-19
Identities = 65/192 (33%), Positives = 99/192 (51%), Gaps = 11/192 (5%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T L++G IP + +GT+ Q + E+ V L+ G IDTA YG+E Q
Sbjct: 37 TYTLNTGAKIPALGVGTF----------QDPDSQEETVCQVLQRGMRLIDTARVYGVEQQ 86
Query: 266 VGRALTKKFSEGLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VGR + K G+ RE IF+ TKLW N +H + V A+ SL +L YVDL L+H+P
Sbjct: 87 VGRGIKKS---GVPREEIFLGTKLWCNDFHP-DDVERAVDDSLRDLYTPYVDLLLMHYPC 142
Query: 443 AM------FENDT----LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 592
F D + F+DTWR + K G ++IG+SNF++ +I+ ++
Sbjct: 143 TFKRGEDRFPRDAEGRMIHGETTFVDTWRALEKVVKTGKVRAIGVSNFSKGEIETLLRET 202
Query: 593 LEKPSALQIELN 628
P+ Q+E++
Sbjct: 203 STVPAVHQMEVH 214
>UniRef50_A7P424 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 247
Score = 96.7 bits (230), Expect = 4e-19
Identities = 56/156 (35%), Positives = 88/156 (56%), Gaps = 11/156 (7%)
Frame = +2
Query: 194 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL--KRESIFITTKLWNSYHEREQV 367
+++ A+E GY H D Y E +G A+ K GL R+ +FIT+KLW S ++V
Sbjct: 37 SILTAIELGYRHFDCVAAYLSEKPLGEAIKKAVKLGLIKSRDELFITSKLWCSDAHHDRV 96
Query: 368 IPALRKSLE---------NLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKK 520
+PAL+ +L+ NL L+Y+DLYLIHW +D L +D W+ M D +K
Sbjct: 97 LPALQNTLKISSILSFSKNLQLDYLDLYLIHW------SDGHLP-IDLGSVWKAMEDFQK 149
Query: 521 LGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
L LTK+IG+SNF+ +++ ++ + P+ Q+ N
Sbjct: 150 LSLTKAIGVSNFSCNKLEELLQTASILPAVNQVSEN 185
>UniRef50_A7RRF6 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 275
Score = 96.3 bits (229), Expect = 5e-19
Identities = 53/148 (35%), Positives = 85/148 (57%)
Frame = +2
Query: 185 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 364
T+QAV++ALE GY IDTA Y E +VG AL + + R +++ TK++++ H E+
Sbjct: 30 TKQAVLWALENGYRMIDTAASYNNEKRVGEALRES---AVPRSEVYLVTKVYHTDHGYEK 86
Query: 365 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 544
+ A +SL L ++YVDLYLIH+P+ + +W M + + GLT+SIG
Sbjct: 87 TMKAYDRSLSALGVDYVDLYLIHFPVP----------AGVVGSWEAMAELQGKGLTRSIG 136
Query: 545 ISNFNQEQIQRIIDSGLEKPSALQIELN 628
+SNFN ++ + + P QIE++
Sbjct: 137 VSNFNIHHLEALQKHSVIPPVVNQIEVH 164
>UniRef50_Q5FT75 Cluster: Putative 2,5-diketo-D-gluconic acid
reductase; n=1; Gluconobacter oxydans|Rep: Putative
2,5-diketo-D-gluconic acid reductase - Gluconobacter
oxydans (Gluconobacter suboxydans)
Length = 279
Score = 95.5 bits (227), Expect = 9e-19
Identities = 58/180 (32%), Positives = 88/180 (48%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
+ G +P + LG W P + +V + A++ GY +DTA Y E+ V
Sbjct: 14 ISFHDGHTMPQIGLGVW--ETPPDETAEVVKE-------AVKLGYRSVDTARLYKNEEGV 64
Query: 269 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
G+ L IF+TTKLWN + + A +S L +DLYLIHWP+
Sbjct: 65 GKGLED-------HPEIFLTTKLWNDEQGYDSTLRAYEESARLLRRPVLDLYLIHWPMPA 117
Query: 449 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
+++TW+ +++ KK G KSIG+SNF E ++RI+D+ P QIEL+
Sbjct: 118 --------QGQYVETWKALVELKKSGRVKSIGVSNFESEHLERIMDATGVVPVVNQIELH 169
>UniRef50_A6NPD6 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Bacteroides capillosus ATCC 29799
Length = 287
Score = 95.1 bits (226), Expect = 1e-18
Identities = 63/181 (34%), Positives = 94/181 (51%), Gaps = 3/181 (1%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQVG 271
LS+G +IP V GT+ T D + AV+ A+ GY H DTA YG E +G
Sbjct: 10 LSNGLSIPAVGFGTYK-----------TGDGDSAVLSNAIAQGYRHFDTASFYGTETALG 58
Query: 272 RALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 451
+A+ + + RE F+T+KLW + + + A +LE L +Y+DLYLIHWP
Sbjct: 59 QAVAES---DIPREDFFLTSKLWKTEMGYDAALRAFDATLERLGTDYLDLYLIHWP---- 111
Query: 452 ENDTLLDNVDFLD--TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 625
D L++ LD TWR + + GL ++IG+SNF ++ I+ S P Q+E
Sbjct: 112 RPDLELEDWAKLDRETWRALERLYESGLVRAIGVSNFLPHHLEPILASANVAPMVDQLEF 171
Query: 626 N 628
+
Sbjct: 172 H 172
>UniRef50_Q5TNP1 Cluster: ENSANGP00000029046; n=2; Culicidae|Rep:
ENSANGP00000029046 - Anopheles gambiae str. PEST
Length = 331
Score = 94.7 bits (225), Expect = 2e-18
Identities = 69/193 (35%), Positives = 104/193 (53%), Gaps = 14/193 (7%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T +L++G +IP+ GT+ H + + QV + YALEAGY HIDTA Y E+
Sbjct: 33 TFKLNTGFDIPLAGFGTYQIHGQE-LIYQVLD-------YALEAGYRHIDTAVVYRNEEY 84
Query: 266 VGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPAL-RKSLENLNLEYVDLYLIHWP 439
+G AL + LKRE IFIT+KL + + E + + RKSL NL +Y+DLYLIHWP
Sbjct: 85 IGTALKTLLPKYNLKREDIFITSKLISQSGKDEAFVEQMVRKSLANLQTDYLDLYLIHWP 144
Query: 440 IA---------MFEND-TLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII- 583
+F T DNV + +W + ++ G +SIG+SN+ + ++ ++
Sbjct: 145 GVSGKCGRWKWLFGMQVTHPDNVKYRAASWNALSKLEREGCLRSIGVSNYTVKHLKEMLA 204
Query: 584 DSGLEKPSALQIE 622
D P+ Q+E
Sbjct: 205 DCKGIVPAVNQVE 217
>UniRef50_Q927P9 Cluster: Lin2739 protein; n=12; Bacteria|Rep:
Lin2739 protein - Listeria innocua
Length = 283
Score = 94.3 bits (224), Expect = 2e-18
Identities = 59/181 (32%), Positives = 93/181 (51%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T++L++G +P++ GT+ + + EQAV A+ AGY HIDTA Y E+
Sbjct: 3 TVKLNNGIEVPILGFGTYQ--------ITDAGEAEQAVKEAIAAGYRHIDTAQSYMNEEA 54
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VGR + + G+ R+ +FITTK+W + V+ + +SL+ L L+Y+DL LIH P
Sbjct: 55 VGRGIA---ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYIDLLLIHQPYN 111
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 625
D W M + + G K+IG+SNF +++ + P QIE+
Sbjct: 112 -----------DVYGAWMAMEELQAQGKIKAIGVSNFGVDRVVDLAAFNDITPQVNQIEI 160
Query: 626 N 628
N
Sbjct: 161 N 161
>UniRef50_Q89JN4 Cluster: Oxidoreductase; n=8; Rhizobiales|Rep:
Oxidoreductase - Bradyrhizobium japonicum
Length = 272
Score = 93.9 bits (223), Expect = 3e-18
Identities = 58/178 (32%), Positives = 94/178 (52%), Gaps = 1/178 (0%)
Frame = +2
Query: 98 SSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
++G IP + LGTW L RP +VV+ AL GY HIDTA Y E +VG
Sbjct: 6 ANGARIPAIGLGTWELSGRPCARVVE----------QALRLGYRHIDTAQVYDNEREVGD 55
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 454
+ + G++R+ +F+TTK+W ++ + ++++SL L L VDL L+HWP +
Sbjct: 56 GVR---ASGVRRDDVFLTTKVWTNHFAPNDLERSVKESLARLRLPSVDLLLLHWPNS--- 109
Query: 455 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
+V +T + A+++GLT+ IG+SNF I++ + E Q+E +
Sbjct: 110 ------HVPLAETLGALSHARQMGLTRHIGVSNFTVALIEQAVALSPEPLVCNQVEFH 161
>UniRef50_Q838E0 Cluster: Oxidoreductase, aldo/keto reductase
family; n=24; Bacilli|Rep: Oxidoreductase, aldo/keto
reductase family - Enterococcus faecalis (Streptococcus
faecalis)
Length = 279
Score = 93.9 bits (223), Expect = 3e-18
Identities = 59/185 (31%), Positives = 94/185 (50%), Gaps = 1/185 (0%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
+ T+ L++G IP + LG + P + +V E+ +I GY IDTA YG
Sbjct: 5 LADTVTLNNGTKIPGMGLGVF--QIPDEETAKVV---EEGIIN----GYRLIDTAQIYGN 55
Query: 257 EDQVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
E G + + GL RE +F+T+K+WN++ ++ I A SLE L L+Y+DLYLIH
Sbjct: 56 ESGTGAGIKAGLAATGLNREDLFVTSKVWNAHISYDETIQAFNDSLERLGLDYLDLYLIH 115
Query: 434 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 613
WP N + ++W+ + G K+IG+SNF ++ ++ P
Sbjct: 116 WP----------GNNSYKESWQALETLYAEGKVKAIGVSNFQVHHLEDLLSYAKVVPVIN 165
Query: 614 QIELN 628
Q+EL+
Sbjct: 166 QVELH 170
>UniRef50_Q1RFP0 Cluster: 2,5-diketo-D-gluconic acid reductase A;
n=21; Bacteria|Rep: 2,5-diketo-D-gluconic acid reductase
A - Escherichia coli (strain UTI89 / UPEC)
Length = 294
Score = 93.9 bits (223), Expect = 3e-18
Identities = 60/159 (37%), Positives = 85/159 (53%), Gaps = 4/159 (2%)
Frame = +2
Query: 164 VVQVTNDT--EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTK 334
V QVT+ +Q+V+ A+ GY IDTA YG ED VG A+ + SEGL RE +FIT+K
Sbjct: 24 VFQVTDKDVCKQSVLNAIRTGYRLIDTAAVYGNEDAVGEAVREAISEGLCTREELFITSK 83
Query: 335 LWNSYHEREQVIPA-LRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMID 511
LW + + A + SL+ LEY DLYL+H + D+ WR + D
Sbjct: 84 LWVQDMLNQDIAAAGIEASLKKSGLEYFDLYLLHQAMR-----------DYFSAWRALED 132
Query: 512 AKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
A + G K+IG+SNF + ++ KP Q+EL+
Sbjct: 133 AYEEGKLKAIGVSNFYPHVLANFCETVRVKPMVNQVELH 171
>UniRef50_Q18483 Cluster: Putative uncharacterized protein; n=2;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 287
Score = 93.9 bits (223), Expect = 3e-18
Identities = 55/172 (31%), Positives = 90/172 (52%), Gaps = 1/172 (0%)
Frame = +2
Query: 110 NIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKK 289
N+P++ +GTW VQ Q + + GY IDTA Y E ++GR L K
Sbjct: 10 NMPLIGIGTWQ--------VQKEEILRQVIDAGFKEGYRFIDTAQVYNNEAKIGRILEKL 61
Query: 290 F-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL 466
+ GLKRE I+IT+KL S ++ ++ +SL NL +EY+DL LIHWP + +++
Sbjct: 62 LPANGLKREDIWITSKLAPSNAGVKKARESIEESLSNLKVEYLDLLLIHWPGSSLKSENP 121
Query: 467 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
+ +++W M + G +S+G+SNF ++ + P+ Q+E
Sbjct: 122 ANKKLRVESWNVMCEMMAEGKLRSVGVSNFEICHLEELKKDSNVVPAVNQVE 173
>UniRef50_Q4PDR0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 339
Score = 93.9 bits (223), Expect = 3e-18
Identities = 61/198 (30%), Positives = 100/198 (50%), Gaps = 17/198 (8%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+P+ L++G +P V +G W G G+ N+ A++ A++ GY H+DTA Y E
Sbjct: 5 IPSFTLNTGAKLPSVGMGCWQGQPGPGR----DNELVDALVRAIKVGYRHLDTATGYRNE 60
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
+VG+A+ + G+ R IF+TTKL H+ V+ L SL L ++Y+DL+L+HW
Sbjct: 61 AEVGQAVRQS---GVARSEIFVTTKLRPGGVHD---VVQELENSLNELGIDYIDLWLLHW 114
Query: 437 PIAMFENDTLLDNVD-------------FLDTWRGMIDA---KKLGLTKSIGISNFNQEQ 568
P ++D + F +TW M D G K+IG+SNF+ +
Sbjct: 115 PQGFTKDDGGFGTGESFGLEHQKHLGPTFNETWAKMEDVFLNSHKGKVKAIGVSNFSIKN 174
Query: 569 IQRIIDSGLEKPSALQIE 622
++ + + P+ QIE
Sbjct: 175 LEILAKTSKVTPAVNQIE 192
>UniRef50_Q7XY49 Cluster: Mannose 6-phosphate reductase; n=1;
Griffithsia japonica|Rep: Mannose 6-phosphate reductase
- Griffithsia japonica (Red alga)
Length = 174
Score = 90.6 bits (215), Expect(2) = 4e-18
Identities = 50/116 (43%), Positives = 71/116 (61%), Gaps = 1/116 (0%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T L SG +P+ GTW K V +TEQAV AL AGY HID A Y E
Sbjct: 5 TATLQSGAKMPLNGFGTW-----KASV----EETEQAVTAALRAGYRHIDCAAVYWNEAA 55
Query: 266 VGRALTKKFSEGL-KRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 430
VG A++K S G+ KRE +FIT+K+WN+ H ++V+ + R+SL++ ++Y DL+L+
Sbjct: 56 VGTAISKAISGGVVKREDLFITSKVWNTCHATDKVVDSCRQSLKDHQVDYFDLFLV 111
Score = 23.4 bits (48), Expect(2) = 4e-18
Identities = 12/42 (28%), Positives = 22/42 (52%)
Frame = +2
Query: 506 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNL 631
+D L L + IG+SN++ + ++ KPS Q E ++
Sbjct: 103 VDYFDLFLVRDIGVSNYSVALLVDTLNYARIKPSVNQCEAHV 144
>UniRef50_Q6F7K7 Cluster: 2,5-diketo-D-gluconate reductase; n=20;
Bacteria|Rep: 2,5-diketo-D-gluconate reductase -
Acinetobacter sp. (strain ADP1)
Length = 297
Score = 93.5 bits (222), Expect = 4e-18
Identities = 62/188 (32%), Positives = 98/188 (52%)
Frame = +2
Query: 65 SAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 244
S E +P L L G +IP + GT+ +G DT ++ AL GY +D+A+
Sbjct: 17 SIEKNIPDLILHDGHSIPALGFGTYTLKGQQGV------DT---MLRALGHGYRMLDSAF 67
Query: 245 KYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLY 424
Y E VG A+ + GL R+ IFIT+KL +H ++ + + +SL + +Y+DLY
Sbjct: 68 NYENEGAVGAAVRQS---GLLRDEIFITSKLPGRHHAYDKAMETIEESLYRMQFDYLDLY 124
Query: 425 LIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKP 604
LIHWP +++ W+ +IDA+K G +SIG+SNF + I+ + P
Sbjct: 125 LIHWPNP--------QQGLYIEAWQALIDAQKKGYIRSIGVSNFLPKHIETLRRETGVIP 176
Query: 605 SALQIELN 628
Q+EL+
Sbjct: 177 VINQVELH 184
>UniRef50_Q6CEJ0 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 302
Score = 93.5 bits (222), Expect = 4e-18
Identities = 62/186 (33%), Positives = 97/186 (52%), Gaps = 1/186 (0%)
Frame = +2
Query: 74 LIVPTLQLSSGGNIPVVALGTWLG-HRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKY 250
+ VP ++LS+G IP + G+ RP G+ + + AV+ A+ AG+ HIDTA Y
Sbjct: 1 MTVPKVKLSNGLEIPAIGFGSGTKWKRPPGEKEE--RELIDAVVSAINAGHLHIDTAEFY 58
Query: 251 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 430
G E Q+G A+ + G+ R+ IF+T+K + I ++ L+ L +Y DL+LI
Sbjct: 59 GTEKQIGEAIKE---SGVPRKDIFLTSKTLFGL-LADDPIESISNQLKTLQTDYFDLFLI 114
Query: 431 HWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 610
H P ND + N D W + + GL K+IG+SN + +++ II KP
Sbjct: 115 HVP----PNDDI--NYDLAKAWGVLEQLYEKGLAKAIGVSNHSPAELETIIKVAKIKPHV 168
Query: 611 LQIELN 628
QIE +
Sbjct: 169 NQIEFH 174
>UniRef50_Q4P1G1 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 320
Score = 93.5 bits (222), Expect = 4e-18
Identities = 64/186 (34%), Positives = 99/186 (53%), Gaps = 1/186 (0%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+PT++L+SG +P +A GT G + +D + V AL++G+ ID A Y E
Sbjct: 3 IPTVRLASGLELPRLAFGT-------GTALY-NSDAAKQVTMALDSGFRFIDGAEVYANE 54
Query: 260 DQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
+G + S GLKR I++ TK+ + Q A++ L+ L ++ +D YL+H
Sbjct: 55 ASMGAGIESFLASSGLKRNDIYVLTKVGKEGMKDLQ--SAIKVELQKLKVDQLDSYLLHL 112
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P D L NVD W+ + K+ GLTKSIG+SN+ IQ+++D+GL P Q
Sbjct: 113 PPR--GQDGLPSNVD---AWKELEKIKQAGLTKSIGVSNWLASDIQQLLDAGLSVPDINQ 167
Query: 617 IELNLN 634
IE + N
Sbjct: 168 IEFHNN 173
>UniRef50_UPI00015B5BD7 Cluster: PREDICTED: similar to aldo-keto
reductase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to aldo-keto reductase - Nasonia vitripennis
Length = 310
Score = 93.1 bits (221), Expect = 5e-18
Identities = 60/183 (32%), Positives = 108/183 (59%), Gaps = 5/183 (2%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
L+L++G ++P+V +GT+ + +G+ V ++ + + G+ IDTA Y E+ +
Sbjct: 26 LRLNNGYDMPLVGIGTY---KVRGREV-----IKRVIDESFAVGFRSIDTAVVYRNEEDI 77
Query: 269 GRALTKKFSE-GLKRESIFITTKLWNSYH-EREQVIPALRKSLENLNLEYVDLYLIHWPI 442
G AL + + LKRE IFIT+KL S + + +++ ++ SL+ L+ Y+DLYLIHWP
Sbjct: 78 GLALKELLPKYNLKREDIFITSKLSPSDNGDPDKIRKSVEDSLKALDTSYLDLYLIHWPG 137
Query: 443 AMFENDTLLDNVDF-LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID--SGLEKPSAL 613
A + DN + TW +++ ++ GL +SIG+SN+ ++ +++ SG+ KP
Sbjct: 138 ASRILENSPDNPKLRVTTWATLVELQQKGLLRSIGVSNYTVGHLEHLLEHCSGV-KPDVN 196
Query: 614 QIE 622
Q+E
Sbjct: 197 QVE 199
>UniRef50_UPI000155CAC7 Cluster: PREDICTED: hypothetical protein;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
hypothetical protein - Ornithorhynchus anatinus
Length = 419
Score = 93.1 bits (221), Expect = 5e-18
Identities = 59/145 (40%), Positives = 82/145 (56%), Gaps = 1/145 (0%)
Frame = +2
Query: 74 LIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHIDTAYKY 250
L VPT+ L++G NIP++ LGT H V + AVIYAL E G HIDTA +Y
Sbjct: 10 LPVPTVPLANGLNIPILGLGT--SH--------VGGYSHDAVIYALKECGIRHIDTAKRY 59
Query: 251 GIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLI 430
G E +G+A+ + G+KRE ++ITTKLW + + E + +S L +EY+DL+LI
Sbjct: 60 GCELLLGKAIQES---GVKREELWITTKLWLTDYGYESAKQSCLESCNRLGVEYLDLFLI 116
Query: 431 HWPIAMFENDTLLDNVDFLDTWRGM 505
HWP A + +TWR M
Sbjct: 117 HWPDAQLPGKS--SREARAETWRAM 139
>UniRef50_Q929C8 Cluster: Lin2349 protein; n=12; Listeria|Rep:
Lin2349 protein - Listeria innocua
Length = 294
Score = 93.1 bits (221), Expect = 5e-18
Identities = 53/143 (37%), Positives = 78/143 (54%)
Frame = +2
Query: 194 AVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIP 373
AV A+E GY DTA Y E VG+A+ + RE +FI++K+WN ++ +
Sbjct: 36 AVEKAIEVGYRLFDTAAVYNNEAIVGQAI---LDSAVPREELFISSKVWNGDLGYDETLF 92
Query: 374 ALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISN 553
A ++L NL L+Y+DLYLIHWP+A + D+WR M L KSIG++N
Sbjct: 93 AFERTLRNLKLDYLDLYLIHWPVA----------GKYRDSWRAMERLHDEKLIKSIGVAN 142
Query: 554 FNQEQIQRIIDSGLEKPSALQIE 622
F Q + ++ + EKP Q+E
Sbjct: 143 FKQHHLSDLLVAANEKPVLNQVE 165
>UniRef50_Q9X265 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Thermotoga|Rep: Oxidoreductase, aldo/keto
reductase family - Thermotoga maritima
Length = 274
Score = 92.7 bits (220), Expect = 7e-18
Identities = 59/183 (32%), Positives = 98/183 (53%), Gaps = 6/183 (3%)
Frame = +2
Query: 101 SGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQAVIY--ALEAGYTHIDTAYKYG---IED 262
+G IP + LGTW +G + + D E + A++ GYTHIDTA YG E+
Sbjct: 9 TGEEIPALGLGTWGIGGF---ETPDYSRDEEMVELLKTAIKMGYTHIDTAEYYGGGHTEE 65
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
+G+A+ K F +RE +FI +K+W ++ R+ ++ +L +L+ L+ +YVDLYLIHWP
Sbjct: 66 LIGKAI-KDF----RREDLFIVSKVWPTHLRRDDLLRSLENTLKRLDTDYVDLYLIHWP- 119
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
+ +T M + + GL + IG+SNF++ ++ I E Q++
Sbjct: 120 --------NPEIPLEETLSAMAEGVRQGLIRYIGVSNFDRRLLEEAISKSQEPIVCDQVK 171
Query: 623 LNL 631
N+
Sbjct: 172 YNI 174
>UniRef50_Q8Y463 Cluster: Lmo2592 protein; n=40; Bacteria|Rep:
Lmo2592 protein - Listeria monocytogenes
Length = 283
Score = 92.7 bits (220), Expect = 7e-18
Identities = 60/183 (32%), Positives = 97/183 (53%), Gaps = 2/183 (1%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTN--DTEQAVIYALEAGYTHIDTAYKYGIE 259
T++L++G +P++ GT+ Q+T+ + E AV A++AGY HIDTA Y E
Sbjct: 3 TVKLNNGVEVPILGFGTY----------QITDAAEAEHAVKDAIKAGYRHIDTAQSYMNE 52
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+ VGR + + G+ R+ +FITTK+W + V+ + +SL+ L L+YVDL LIH P
Sbjct: 53 EAVGRGIA---ASGVDRKELFITTKIWVENVSYKGVMSSFDRSLKRLGLDYVDLLLIHQP 109
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
D W M + + G ++IG+SNF+ +++ + P QI
Sbjct: 110 FN-----------DVYGAWIAMEELQASGKIRAIGVSNFSPDRVIDLAAFNEVTPQVNQI 158
Query: 620 ELN 628
E+N
Sbjct: 159 EVN 161
>UniRef50_A2RMU6 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Lactococcus lactis|Rep: Oxidoreductase,
aldo/keto reductase family - Lactococcus lactis subsp.
cremoris (strain MG1363)
Length = 281
Score = 92.7 bits (220), Expect = 7e-18
Identities = 66/176 (37%), Positives = 92/176 (52%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L+ G IP LG + P+G+ TE AV AL GY HIDTA+ Y E VGR
Sbjct: 7 LNDGNIIPQFGLGVY--QIPEGEA------TENAVKEALRLGYRHIDTAHAYQNERSVGR 58
Query: 275 ALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFE 454
A+ S G+ I+IT+KLW S + + A+ + LE LNL+ +DL L+H + +
Sbjct: 59 AI---HSSGIPISEIWITSKLWPS--DYDDASQAIERMLELLNLKQIDLLLLHQQVGNYR 113
Query: 455 NDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
W + +A K G KSIGISNF+ E++ + + KPSALQ+E
Sbjct: 114 K-----------AWIALENAVKSGKVKSIGISNFDGERLVDLFNFADIKPSALQVE 158
>UniRef50_Q7R2T6 Cluster: GLP_291_56367_57278; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_291_56367_57278 - Giardia lamblia
ATCC 50803
Length = 303
Score = 92.7 bits (220), Expect = 7e-18
Identities = 52/159 (32%), Positives = 84/159 (52%), Gaps = 15/159 (9%)
Frame = +2
Query: 191 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSE---GLKRESIFITTKLWNSYHERE 361
+A+ A++ GY H D AY+YG E +G + F++ G+KRE ++I +KLW ++HE E
Sbjct: 19 EAIRSAVKLGYRHFDCAYRYGNERMIGEVFKEIFNDDSYGVKREDLWIVSKLWPNFHEPE 78
Query: 362 QVIPALRKSLENLNLEYVDLYLIHWPIA---MFEND---------TLLDNVDFLDTWRGM 505
+V + ++L +L LEY+D++L+HWP+A + + D TLL TW M
Sbjct: 79 KVAYQISETLRDLQLEYLDVFLMHWPLAIKHLADRDYASSDGKGGTLLGTTPIRKTWEAM 138
Query: 506 IDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
T+ IG+SN + ++ KP Q E
Sbjct: 139 EACVDKKQTRFIGVSNMGTAMLVDLLSYCRIKPFTNQFE 177
>UniRef50_O13848 Cluster: NADH/NADPH dependent indole-3-acetaldehyde
reductase AKR3C2; n=1; Schizosaccharomyces pombe|Rep:
NADH/NADPH dependent indole-3-acetaldehyde reductase
AKR3C2 - Schizosaccharomyces pombe (Fission yeast)
Length = 284
Score = 92.7 bits (220), Expect = 7e-18
Identities = 57/172 (33%), Positives = 90/172 (52%)
Frame = +2
Query: 113 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 292
+P +GT L + KG++ + D+ V AL AG+ HID A YG E++VG AL +
Sbjct: 12 VPAYGVGTALFKKEKGEINRTIVDS---VKNALAAGFIHIDCAEVYGNEEEVGVALKEA- 67
Query: 293 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 472
+ R +FIT+K+ H + + AL +SL L +Y+DLYL+H PI +E
Sbjct: 68 --NVPRSKLFITSKVM---HNVDNIPEALNESLRKLGTDYLDLYLLHSPIPFYEK----- 117
Query: 473 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
+ + W+ M A GL S+G+SNF ++ ++ + P QIE +
Sbjct: 118 KIPISEGWKAMETALGTGLVHSVGVSNFRIPDLEELLKTSTITPRVNQIEFH 169
>UniRef50_P38115 Cluster: D-arabinose dehydrogenase [NAD(P)+] heavy
chain; n=3; Saccharomycetaceae|Rep: D-arabinose
dehydrogenase [NAD(P)+] heavy chain - Saccharomyces
cerevisiae (Baker's yeast)
Length = 344
Score = 92.7 bits (220), Expect = 7e-18
Identities = 72/201 (35%), Positives = 110/201 (54%), Gaps = 25/201 (12%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L++G IP + LGT P K+ + T+QAV A++AGY HIDTA+ Y E VG
Sbjct: 27 LNNGVRIPALGLGT---ANPHEKLAE----TKQAVKAAIKAGYRHIDTAWAYETEPFVGE 79
Query: 275 ALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMF 451
A+ + +G +KRE +FITTK+W ++V +L +SL+ L LEYVDL L HWP+ F
Sbjct: 80 AIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLC-F 136
Query: 452 EN-----------DTLLDNV---------DFLDTWRGM----IDAKKLGLTKSIGISNFN 559
E T +D+ D+L+T++ + +D ++IG+SNF+
Sbjct: 137 EKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPND-HRVRAIGVSNFS 195
Query: 560 QEQIQRIIDSGLEKPSALQIE 622
E ++R+I KP+ Q+E
Sbjct: 196 IEYLERLIKECRVKPTVNQVE 216
>UniRef50_Q3E9M9 Cluster: Uncharacterized protein At5g01670.2; n=7;
Magnoliophyta|Rep: Uncharacterized protein At5g01670.2 -
Arabidopsis thaliana (Mouse-ear cress)
Length = 349
Score = 91.9 bits (218), Expect = 1e-17
Identities = 70/224 (31%), Positives = 110/224 (49%), Gaps = 34/224 (15%)
Frame = +2
Query: 59 FTSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYAL-EAGYTHID 235
FTS + + +L SG IP V LGTW + + AV+ A+ E GY HID
Sbjct: 6 FTSEGQNMESFRLLSGHKIPAVGLGTW----------RSGSQAAHAVVTAIVEGGYRHID 55
Query: 236 TAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQV---IPAL--------- 379
TA++YG + +VG+ + + GL+R +F+T+KLW + R+ + P +
Sbjct: 56 TAWEYGDQREVGQGIKRAMHAGLERRDLFVTSKLWYTLILRKMINLSSPLMNVLVGTCLN 115
Query: 380 -----------RKSLEN----LNLEYVDLYLIHWPIAMFENDTLLDNV-DFLD-----TW 496
R +L+N L LEY+DLYLIHWPI + E + D LD W
Sbjct: 116 KRCTELSPERVRPALQNTLKELQLEYLDLYLIHWPIRLREGASKPPKAGDVLDFDMEGVW 175
Query: 497 RGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
R M + K L ++IG+ NF ++ +++ P+ Q+E++
Sbjct: 176 REMENLSKDSLVRNIGVCNFTVTKLNKLLGFAELIPAVCQMEMH 219
>UniRef50_Q02198 Cluster: Morphine 6-dehydrogenase; n=5;
Bacteria|Rep: Morphine 6-dehydrogenase - Pseudomonas
putida
Length = 296
Score = 91.9 bits (218), Expect = 1e-17
Identities = 58/182 (31%), Positives = 94/182 (51%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P + L++G +P + LG + +T A+ A+ +GY IDTA Y E
Sbjct: 6 PLINLNNGVKMPALGLGVFAAS---------AEETASAIASAISSGYRLIDTARSYNNEA 56
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
QVG + + G+ R +F+TTKL+N + E+ + A +SL L L+YVDLYL+HWP
Sbjct: 57 QVGEGIR---NSGVDRAEMFVTTKLFNCDYGYERALRAFDESLGRLGLDYVDLYLLHWPT 113
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
+ N T + +W+ G ++IG+ NF ++Q+ +I + P+ QIE
Sbjct: 114 KDW-NAT-------IQSWKAAEKILGDGRARAIGVCNFLEDQLDELIAASDVVPAVNQIE 165
Query: 623 LN 628
L+
Sbjct: 166 LH 167
>UniRef50_Q03U37 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=5; Lactobacillus|Rep: Aldo/keto
reductase of diketogulonate reductase family -
Lactobacillus brevis (strain ATCC 367 / JCM 1170)
Length = 282
Score = 91.5 bits (217), Expect = 2e-17
Identities = 62/182 (34%), Positives = 92/182 (50%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
I T +L+ G +PV+ GT+L + Q T +T A+ A +AGY DTA Y
Sbjct: 6 ITATRKLADGRQMPVMGFGTYLLND------QPTMNT--AIQTAWDAGYRMFDTAMLYRN 57
Query: 257 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
ED +G A+ + GL RE +F+T+K+ +Q + A+ SL+ L +Y+DL LIHW
Sbjct: 58 EDILGPAIQQL---GLPREGLFLTSKVAEIVQGYDQTMKAVEGSLKRLQTDYLDLLLIHW 114
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P+ F DTWR + K G KSIG+SN+ ++ + E P Q
Sbjct: 115 PV----------REHFFDTWRALEQLKADGQVKSIGVSNYTIAHLELLATKAKEMPVVNQ 164
Query: 617 IE 622
+E
Sbjct: 165 VE 166
>UniRef50_A4FEB9 Cluster: 2,5-diketo-D-gluconic acid reductase; n=1;
Saccharopolyspora erythraea NRRL 2338|Rep:
2,5-diketo-D-gluconic acid reductase - Saccharopolyspora
erythraea (strain NRRL 23338)
Length = 159
Score = 91.5 bits (217), Expect = 2e-17
Identities = 56/121 (46%), Positives = 70/121 (57%), Gaps = 1/121 (0%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTND-TEQAVIYALEAGYTHIDTAYKYGI 256
VPT+ L++G +P + G V QV D T AV ALEAGY IDTA YG
Sbjct: 4 VPTVTLNNGVEMPQLGYG----------VFQVPEDETAAAVGAALEAGYRSIDTAAAYGN 53
Query: 257 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
E VGRAL GL R+ +F+TTKLWN+ + + A SLE L L+++DLYLIHW
Sbjct: 54 EAAVGRALA---GSGLARDELFVTTKLWNADQGYDNALRAFDTSLELLGLDHLDLYLIHW 110
Query: 437 P 439
P
Sbjct: 111 P 111
>UniRef50_A3VHZ9 Cluster: Oxidoreductase; n=1; Rhodobacterales
bacterium HTCC2654|Rep: Oxidoreductase - Rhodobacterales
bacterium HTCC2654
Length = 278
Score = 91.5 bits (217), Expect = 2e-17
Identities = 58/182 (31%), Positives = 91/182 (50%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
PT+ L++G +P + LGTW ++ +AV A+E GY IDTA Y E
Sbjct: 8 PTVTLANGVEMPQLGLGTW---------PMTDDEAAKAVATAIETGYRLIDTAENYKNET 58
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
VG+ + G+ R+ +F+TTK+ +H + A SLE L L+Y+DL+LIHWP
Sbjct: 59 GVGQGIR---DAGVARDEVFLTTKMNKQWHSVDGARRACEASLERLGLDYIDLFLIHWPN 115
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
D +++ + G+ GL ++IG SNF + + +G P QI+
Sbjct: 116 P--------DQGTYVEAFEGLTRLLDAGLVRAIGTSNFLPHHLNDLFAAGF-VPHVNQIQ 166
Query: 623 LN 628
L+
Sbjct: 167 LD 168
>UniRef50_Q4V008 Cluster: Oxidoreductase; n=4; Proteobacteria|Rep:
Oxidoreductase - Xanthomonas campestris pv. campestris
(strain 8004)
Length = 267
Score = 91.1 bits (216), Expect = 2e-17
Identities = 63/173 (36%), Positives = 93/173 (53%), Gaps = 1/173 (0%)
Frame = +2
Query: 113 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 292
+P LGT+ R K +VV +V AL GY IDTA Y E QVG+A+
Sbjct: 3 VPAFGLGTF---RLKDQVVI------DSVRNALALGYRAIDTAQIYDNEAQVGQAIA--- 50
Query: 293 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 472
G+ R+ +F+TTK+W R+ + P+L++SL L +YVDL LIHWP + D
Sbjct: 51 DAGVPRDQLFVTTKIWVDRFSRDTLQPSLQESLRKLGTDYVDLTLIHWP-------SPKD 103
Query: 473 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLEKPSALQIELN 628
V + + DAK GLT++IG+SNF ++ I+ G + + QIE++
Sbjct: 104 QVPMREYLEALADAKAQGLTRAIGVSNFTIALTRQAIEILGADAIATNQIEVH 156
>UniRef50_Q15NA5 Cluster: Aldo/keto reductase; n=2;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 273
Score = 91.1 bits (216), Expect = 2e-17
Identities = 54/153 (35%), Positives = 84/153 (54%), Gaps = 1/153 (0%)
Frame = +2
Query: 179 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 358
+D + AV AL+ GY HIDTA Y E +VG A++ + + R +F+TTK+W
Sbjct: 24 DDAKLAVENALDVGYRHIDTAQAYENEAEVGDAIS---ASKISRGELFVTTKVWFDNLSA 80
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 538
++ I +++ SL LN +YVDL L+HWP D + ++L + K+ GLT+
Sbjct: 81 DKFITSVQNSLTQLNTDYVDLLLVHWP----SPDNKVSMAEYLKELKA---CKERGLTRH 133
Query: 539 IGISNFNQEQIQRIID-SGLEKPSALQIELNLN 634
IG+SNF Q Q+ + G + QIE++ N
Sbjct: 134 IGVSNFTQSQLDEALSILGKDHILTNQIEVHPN 166
>UniRef50_A5ZYE6 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus obeum ATCC 29174|Rep: Putative
uncharacterized protein - Ruminococcus obeum ATCC 29174
Length = 263
Score = 91.1 bits (216), Expect = 2e-17
Identities = 57/150 (38%), Positives = 86/150 (57%), Gaps = 3/150 (2%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 361
+ E A+ A++ GY +DTA Y E+ VG + K G+ R+ +FITTK+WN+
Sbjct: 16 EAEDAIAAAVQNGYRLLDTASAYKNEEFVGCGIAKC---GVPRKDLFITTKIWNNAQRLG 72
Query: 362 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 541
V A ++SL+ L L+Y+DLYLIHWP+ FL+TW+ M + G SI
Sbjct: 73 DVEGAFQRSLDRLGLDYIDLYLIHWPVPGC----------FLNTWKDMEKILESGRALSI 122
Query: 542 GISNF---NQEQIQRIIDSGLEKPSALQIE 622
G+SNF + E+++R+ SG+ P+ QIE
Sbjct: 123 GVSNFEIRHLEELRRV--SGI-VPAVNQIE 149
>UniRef50_A0JRJ6 Cluster: Aldo/keto reductase; n=2;
Micrococcineae|Rep: Aldo/keto reductase - Arthrobacter
sp. (strain FB24)
Length = 281
Score = 91.1 bits (216), Expect = 2e-17
Identities = 65/184 (35%), Positives = 97/184 (52%), Gaps = 1/184 (0%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVT-NDTEQAVIYALEAGYTHIDTAYKYGI 256
+P L L++G IP + G V QV +T++ V ALEAGY HIDTA Y
Sbjct: 9 IPQLTLNNGVKIPQLGFG----------VFQVPPEETQRIVEDALEAGYRHIDTAAAYRN 58
Query: 257 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
E VG A++ + G+ RE IFITTKL N E+ A + S + L +E+VDLYLIHW
Sbjct: 59 EAGVGAAIS---ASGIPREDIFITTKLRNG--EQGNAHEAFQNSRKALGVEFVDLYLIHW 113
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P+ + L + + W+ M ++IG+SNF E + ++ + P+ Q
Sbjct: 114 PV---PSQGL-----YTEAWKAMEKLYANSQIRAIGVSNFLGEHLDTLLPAADVVPAVNQ 165
Query: 617 IELN 628
+E++
Sbjct: 166 VEIH 169
>UniRef50_UPI00006CA3CB Cluster: oxidoreductase, aldo/keto reductase
family protein; n=3; Tetrahymena thermophila SB210|Rep:
oxidoreductase, aldo/keto reductase family protein -
Tetrahymena thermophila SB210
Length = 299
Score = 90.6 bits (215), Expect = 3e-17
Identities = 63/191 (32%), Positives = 95/191 (49%), Gaps = 2/191 (1%)
Frame = +2
Query: 65 SAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAY 244
S++ I + LS+G +P LG+ VQ + + AL+ GY HIDTA
Sbjct: 2 SSQEIQKVITLSNGQKMPAFGLGS--------SRVQSVEEVTNLIRKALDVGYRHIDTAQ 53
Query: 245 KYGIEDQVGRALTKKFSEG-LKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 421
Y E +G AL F EG KRE IF+ TK + + + +++ L+ L ++YVDL
Sbjct: 54 MYENEQFIGAALKTIFGEGKYKREDIFLVTK--QASIKGVSCLEIMKEQLQKLQVDYVDL 111
Query: 422 YLIHWPIAMFEND-TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 598
LIH P+A +D ++ W + LGL K +G+SNFN + I ++
Sbjct: 112 LLIHVPLAAPSDDYQQWNHKPVHQIWAEFEEIHSLGLAKGLGVSNFNCQMIIDLLAYCKI 171
Query: 599 KPSALQIELNL 631
KP QIEL++
Sbjct: 172 KPLVNQIELHV 182
>UniRef50_Q5XJM7 Cluster: Zgc:101765; n=5; Eumetazoa|Rep: Zgc:101765
- Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 288
Score = 90.6 bits (215), Expect = 3e-17
Identities = 63/184 (34%), Positives = 97/184 (52%), Gaps = 2/184 (1%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P++ L++ +P++ LGT+ R +G+ DT AV AL+AGY DTA Y E
Sbjct: 6 PSVLLNNDIQMPLLGLGTF---RLQGQ-----EDTYSAVDAALKAGYRAFDTAAVYRNEA 57
Query: 263 QVGRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+G AL + GL RE +FIT+KL + + +KSLE L L Y+DLYLIHWP
Sbjct: 58 HLGHALRCLLPKHGLSREDVFITSKL-GPKDQGSKARNGCQKSLEQLGLGYIDLYLIHWP 116
Query: 440 IAM-FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
+ + +WR + + G ++IG+SN+ E +Q ++ S P+ LQ
Sbjct: 117 GTQGLPVGDKRNPENRAQSWRVLEEFYSEGKFRAIGVSNYTVEHMQELLKSCKVPPAVLQ 176
Query: 617 IELN 628
+E +
Sbjct: 177 VEFH 180
>UniRef50_Q5FK99 Cluster: Oxidoreductase aldo-keto reductase family;
n=5; Lactobacillus|Rep: Oxidoreductase aldo-keto
reductase family - Lactobacillus acidophilus
Length = 289
Score = 90.6 bits (215), Expect = 3e-17
Identities = 62/185 (33%), Positives = 92/185 (49%), Gaps = 2/185 (1%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTE--QAVIYALEAGYTHIDTAYKYG 253
+P ++L+ G IP + G V Q++N E +AV A+ GY IDTA Y
Sbjct: 4 IPKIKLNDGNEIPQLGFG----------VFQISNHDEAVKAVESAISNGYRLIDTAEAYN 53
Query: 254 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
+ VG A+ + + R+ IF+TTKLW S E+ A+ + L+ L +Y+D+ L+H
Sbjct: 54 NQTAVGEAIK---NSDVNRDDIFLTTKLWVSNFTYEKASKAIDEDLKELGTDYIDMMLLH 110
Query: 434 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL 613
D WR + DA+K G TKSIG+SNF +Q+ + KP
Sbjct: 111 QAYG-----------DVAGAWRALEDAQKAGKTKSIGVSNFWPDQLMNLQLMSNVKPVVN 159
Query: 614 QIELN 628
QIE+N
Sbjct: 160 QIEVN 164
>UniRef50_A7ALH6 Cluster: Putative uncharacterized protein; n=1;
Parabacteroides merdae ATCC 43184|Rep: Putative
uncharacterized protein - Parabacteroides merdae ATCC
43184
Length = 301
Score = 90.6 bits (215), Expect = 3e-17
Identities = 57/182 (31%), Positives = 95/182 (52%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
VPT++L++G +P + +GT+L V ++ + V +A++ G+ IDTA YG E
Sbjct: 29 VPTVKLNNGMEMPQLGVGTFL----------VKDNAAERVCHAIKVGFRLIDTAQGYGNE 78
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+VG + + G+ R +FITTK+ V +L KSL +L +Y+DL LIHWP
Sbjct: 79 KEVGEGICRS---GIDRRELFITTKVNTMEMRGGTVRQSLDKSLADLGTDYIDLVLIHWP 135
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
+ +TW+ + + G +SIG+SNFN + +++ +P QI
Sbjct: 136 V----------KGHIKETWQILEEYVDKGKIRSIGVSNFNPHHLDELLEYARIRPVVNQI 185
Query: 620 EL 625
E+
Sbjct: 186 EI 187
>UniRef50_Q927E1 Cluster: Lin2848 protein; n=13; Listeria|Rep:
Lin2848 protein - Listeria innocua
Length = 280
Score = 90.2 bits (214), Expect = 4e-17
Identities = 51/139 (36%), Positives = 74/139 (53%)
Frame = +2
Query: 206 ALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRK 385
A++ GY DTA Y E ++G S GLKR+ F+TTK+WN+ ++ + A K
Sbjct: 40 AVDVGYRLFDTASFYHNEKELGDFFA---SSGLKRDEFFVTTKMWNTEQGYDETLRAFEK 96
Query: 386 SLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQE 565
S + L L+ VDLYL+HWP + DT F +TWR + GL ++IG+SNF
Sbjct: 97 SQKKLQLDQVDLYLVHWP----KQDT------FFETWRAVEKLYDEGLVRAIGVSNFEAH 146
Query: 566 QIQRIIDSGLEKPSALQIE 622
+ R+ S P Q+E
Sbjct: 147 HLDRLRTSANVLPVVDQLE 165
>UniRef50_Q7NB44 Cluster: ARA1; n=3; Firmicutes|Rep: ARA1 -
Mycoplasma gallisepticum
Length = 289
Score = 90.2 bits (214), Expect = 4e-17
Identities = 58/148 (39%), Positives = 80/148 (54%)
Frame = +2
Query: 185 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 364
T +AV ALE GY H+D A Y E+Q+ + K S G+ R+ IFIT+K+WN E
Sbjct: 38 TVEAVKTALEVGYRHLDCAEIY--ENQLSVSQGIKLS-GVNRKEIFITSKIWNDDKGYES 94
Query: 365 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 544
A K L++L+LEY+DL LIHWPI D V+ TW+ M + G K+IG
Sbjct: 95 TKKAFHKILKDLDLEYLDLLLIHWPIGKGFKDN-WQEVN-AQTWKAMEEFYLEGKIKAIG 152
Query: 545 ISNFNQEQIQRIIDSGLEKPSALQIELN 628
+SNF I+ + S P Q+E +
Sbjct: 153 LSNFLVHHIEALKKSAKILPMVNQLEFH 180
>UniRef50_A0L1A2 Cluster: Aldo/keto reductase; n=8;
Gammaproteobacteria|Rep: Aldo/keto reductase -
Shewanella sp. (strain ANA-3)
Length = 280
Score = 90.2 bits (214), Expect = 4e-17
Identities = 53/135 (39%), Positives = 75/135 (55%)
Frame = +2
Query: 179 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 358
N AV+ ALE G HIDTA YG E VG A+ + G+ RE +FITTK+W +
Sbjct: 30 NAAFDAVLMALEEGSRHIDTAQIYGNEQAVGDAIN---TSGIPREELFITTKVWTENLTK 86
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 538
E+ ++ SL L +Y+DL LIHWP+ N V++L + ++D GLT+
Sbjct: 87 ERFETSVIDSLTALQTKYLDLLLIHWPL----NSDEPSMVEYLSELKAVLDK---GLTRR 139
Query: 539 IGISNFNQEQIQRII 583
IG+SNF Q+ + I
Sbjct: 140 IGVSNFTNAQLAQAI 154
>UniRef50_A6VNW9 Cluster: Aldo/keto reductase precursor; n=1;
Actinobacillus succinogenes 130Z|Rep: Aldo/keto
reductase precursor - Actinobacillus succinogenes 130Z
Length = 315
Score = 89.8 bits (213), Expect = 5e-17
Identities = 59/182 (32%), Positives = 98/182 (53%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
T++L++G +P++ +G W TE++V AL+AGY IDTA Y E
Sbjct: 44 TVKLNNGIEMPIIGIGVW---------TLTPEQTEKSVGEALKAGYRLIDTARMYRNEQA 94
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VGRA+ G+ RE IFITTK++ S + A+ + L L+ +Y+DL L+H+P
Sbjct: 95 VGRAVR---DSGIPREEIFITTKIYGS-GDYANAEAAINERLRLLDTDYIDLLLLHYP-- 148
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 625
+NDT W+ M K G ++IG+SN++++ RI+ + P+ +Q E+
Sbjct: 149 -DQNDT--------KAWKVMEQFVKAGKIRAIGLSNYHRKTFNRIMQAATITPAVVQNEV 199
Query: 626 NL 631
++
Sbjct: 200 HI 201
>UniRef50_A3VRL4 Cluster: Putative uncharacterized protein; n=1;
Parvularcula bermudensis HTCC2503|Rep: Putative
uncharacterized protein - Parvularcula bermudensis
HTCC2503
Length = 278
Score = 89.8 bits (213), Expect = 5e-17
Identities = 58/170 (34%), Positives = 90/170 (52%)
Frame = +2
Query: 113 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 292
IP + GTW + +G+ + + T A+E GY HID A Y E +VG +
Sbjct: 11 IPRLGFGTW---QLEGEDARTSTRT------AIETGYRHIDGAAIYKNEKKVGEGIK--- 58
Query: 293 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 472
G+ R+ +F+TTK+WN ++ + A+ +SL+ L L+YV+L L+HWPI ND
Sbjct: 59 DSGIPRDELFVTTKIWNEDIQKGRHSEAVDESLDRLGLDYVNLILLHWPI----ND---- 110
Query: 473 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
+ D + + K+ G K IGISN+NQ Q + + E +A+Q E
Sbjct: 111 -MPIADQVGPLAEIKRSGRAKLIGISNYNQAQFLEAVSASEEPLAAIQCE 159
>UniRef50_Q4FY75 Cluster: Aldo-keto reductase-like protein; n=5;
Trypanosomatidae|Rep: Aldo-keto reductase-like protein -
Leishmania major strain Friedlin
Length = 372
Score = 89.4 bits (212), Expect = 6e-17
Identities = 54/158 (34%), Positives = 80/158 (50%), Gaps = 18/158 (11%)
Frame = +2
Query: 179 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHE 355
++ AV +AL GY H+D A YG E VG AL + + +RE +F+T+KLW +
Sbjct: 43 SEATDAVAFALSCGYRHVDCAKAYGNEAAVGEALAQALRTRCTRREDLFVTSKLWPTDQH 102
Query: 356 REQVIPALRKSLENLNLEYVDLYLIHWPIAM-----FEND------------TLLDNVDF 484
+ V A R +L L L+Y+DLYLIHWP+ M + +D + +V
Sbjct: 103 PDHVEAACRATLAALQLDYLDLYLIHWPVCMRHTPHWTSDEDRYPRHRDGTPAIDTSVTL 162
Query: 485 LDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE 598
LDTW M GL KSIG++N + ++ + E
Sbjct: 163 LDTWTAMNRLVDRGLVKSIGLANCTTAHVNDLVKAVAE 200
>UniRef50_Q1M4Z6 Cluster: Putative aldo-keto reductase/oxidase; n=1;
Rhizobium leguminosarum bv. viciae 3841|Rep: Putative
aldo-keto reductase/oxidase - Rhizobium leguminosarum
bv. viciae (strain 3841)
Length = 274
Score = 88.6 bits (210), Expect = 1e-16
Identities = 56/140 (40%), Positives = 79/140 (56%), Gaps = 3/140 (2%)
Frame = +2
Query: 179 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 358
++ Q VI+ALEAG HIDTA YG E V R + G+ R IFITTK+ +
Sbjct: 23 DEAHQGVIWALEAGCRHIDTAQGYGNEQDVARGIK---DAGVARNEIFITTKVKPDNYGP 79
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 538
V+P++R+SLE L ++ VDL L+HWP N L D+L + + D+ GL +
Sbjct: 80 GAVMPSVRESLEKLRVDQVDLLLLHWPSP--HNKYPL--ADYLGQFAEVFDS---GLARQ 132
Query: 539 IGISNFNQEQIQ---RIIDS 589
IG+SNF + I R++DS
Sbjct: 133 IGVSNFTKAMIDESIRLLDS 152
>UniRef50_Q2U219 Cluster: Aldo/keto reductase family proteins; n=6;
Pezizomycotina|Rep: Aldo/keto reductase family proteins
- Aspergillus oryzae
Length = 294
Score = 88.6 bits (210), Expect = 1e-16
Identities = 55/180 (30%), Positives = 93/180 (51%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P ++L+ +IP++ GT + V + +A+ A+ GY H+D A YG E
Sbjct: 10 PRVKLNDNVSIPILGYGTGTAWYKQAGDDSVNRELVEAIKTAIRLGYRHLDGAEVYGTEA 69
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
++G A+ + G+ RE +F+TTK+ + + + A+ +SL L L YVDLYLIH P
Sbjct: 70 ELGVAIKE---SGIPREELFVTTKVITNIAD---IPSAIDQSLRKLQLNYVDLYLIHSPF 123
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
++D L W M ++ G K+IG+SN++Q ++ + + + P QIE
Sbjct: 124 -FAKSDGELQ-----QAWAAMEKVQQAGKAKAIGVSNYHQSHLEATLKTAVIAPVINQIE 177
>UniRef50_Q11B35 Cluster: Aldo/keto reductase; n=1; Mesorhizobium
sp. BNC1|Rep: Aldo/keto reductase - Mesorhizobium sp.
(strain BNC1)
Length = 253
Score = 88.2 bits (209), Expect = 1e-16
Identities = 56/170 (32%), Positives = 90/170 (52%)
Frame = +2
Query: 113 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 292
+P++ LGTW Q+T++T + V A + GY +DT+ YG + +G A+
Sbjct: 1 MPILGLGTW----------QLTHETARTVRAAFDLGYRMVDTSGDYGTQSAIGEAIR--- 47
Query: 293 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 472
+ GL R+ I++ TK+ E E A + +L L L+Y DL LIH P + L
Sbjct: 48 ASGLDRDDIYLVTKV----EETEDAYNATQANLRELGLDYADLILIHRPPRHGAGEEL-- 101
Query: 473 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
WR +I A++ GLT+ IG+SN++ E I+ ++D+ E P Q+E
Sbjct: 102 -------WRALIRAREDGLTRDIGVSNYSIELIEELVDATGEIPVVNQVE 144
>UniRef50_Q03BE0 Cluster: Aldo/keto reductase family enzyme; n=5;
Lactobacillus|Rep: Aldo/keto reductase family enzyme -
Lactobacillus casei (strain ATCC 334)
Length = 281
Score = 87.8 bits (208), Expect = 2e-16
Identities = 53/177 (29%), Positives = 95/177 (53%), Gaps = 1/177 (0%)
Frame = +2
Query: 104 GGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALT 283
G N+P++ +GTW + +G Q + A+ Y L G T IDTA YG + +L
Sbjct: 8 GVNVPIMGMGTW--YLGEGNAAQSEQEAA-ALKYGLNHGLTVIDTAEMYG--NGAAESLI 62
Query: 284 KKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDT 463
F R +I++ +K + S+ ++ Q++ AL+ SL+ L +Y+DLYL+HW
Sbjct: 63 GSFLGDYDRANIYLISKFYPSHADKRQMLTALKNSLKRLQTDYLDLYLLHW--------- 113
Query: 464 LLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRI-IDSGLEKPSALQIELNL 631
+ +T G+ D +K GL K G+SNF+ + + ++ ++ G ++ +A ++ NL
Sbjct: 114 -RGSTPLAETLEGLQDLQKEGLIKQYGVSNFDVDDMDQLTLEPGGDQIAANEVLYNL 169
>UniRef50_A3UJS6 Cluster: Oxidoreductase; n=3;
Alphaproteobacteria|Rep: Oxidoreductase - Oceanicaulis
alexandrii HTCC2633
Length = 275
Score = 87.8 bits (208), Expect = 2e-16
Identities = 52/153 (33%), Positives = 77/153 (50%)
Frame = +2
Query: 98 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 277
++G +IP + GTW D + V AL+ GY HIDTA YG E VG
Sbjct: 7 ANGADIPKLGFGTWQLE---------DEDAARGVATALKTGYRHIDTAQIYGNEAAVGDG 57
Query: 278 LTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 457
+ G+KRE F+TTK+W + ++++SL+ L +YVDL L+HWP+
Sbjct: 58 WKQS---GVKREDFFLTTKVWRDKFRDGDLQASVKESLDKLKTDYVDLLLLHWPV----- 109
Query: 458 DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNF 556
V +T + M + K+ G + IG+SNF
Sbjct: 110 ----PEVPIAETMKAMNEVKEAGQVRHIGVSNF 138
>UniRef50_Q75E75 Cluster: ABL209Cp; n=1; Eremothecium gossypii|Rep:
ABL209Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 310
Score = 87.8 bits (208), Expect = 2e-16
Identities = 64/185 (34%), Positives = 94/185 (50%), Gaps = 6/185 (3%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYGIEDQV 268
+LS G IP V LG V QV+ T Q ++Y ALE GY D+A Y ED V
Sbjct: 14 RLSDGTQIPSVGLG----------VYQVSEQTVQDLVYEALEVGYRLFDSAQAYHNEDGV 63
Query: 269 GRALTK--KFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLN-LEYVDLYLIHWP 439
R + K + G +RE ++ TTK+ H E +L KSL L Y+DL L+H P
Sbjct: 64 ARGIAAWLKHAPGRRREDVYFTTKINTQNHGYEATKKSLEKSLHAAGPLGYIDLVLVHAP 123
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLE-KPSAL 613
++ D L TW+ + +A G +SIG+SN+ Q+ + ++ GL+ +P
Sbjct: 124 MS--------DRTRRLGTWQALEEAVVEGQVRSIGVSNYGQQHLSELLGWEGLKIRPVVN 175
Query: 614 QIELN 628
Q+E+N
Sbjct: 176 QVEIN 180
>UniRef50_Q3CZS2 Cluster: Oxidoreductase, aldo/keto reductase
family; n=2; Streptococcus agalactiae|Rep:
Oxidoreductase, aldo/keto reductase family -
Streptococcus agalactiae H36B
Length = 245
Score = 87.4 bits (207), Expect = 3e-16
Identities = 53/149 (35%), Positives = 83/149 (55%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 361
+ EQ+V+ AL+ GY IDTA Y E+ VGRA+ K G+ R+ IF+ TKLW E
Sbjct: 30 ECEQSVLDALQVGYRLIDTASGYLNEEAVGRAIKKS---GIPRKEIFVVTKLWIQDASEE 86
Query: 362 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 541
+ PA+ ++L+ L L+Y++LYLIH P+ D+ R + A + +I
Sbjct: 87 KAGPAIDRALKRLQLDYINLYLIHQPMG-----------DYYGACRALEKAYEERKALAI 135
Query: 542 GISNFNQEQIQRIIDSGLEKPSALQIELN 628
G+SNF+ ++Q +I P+ QI++N
Sbjct: 136 GVSNFSNGRVQDLILHNKIIPAVNQIQMN 164
>UniRef50_Q1PV10 Cluster: Putative uncharacterized protein; n=1;
Candidatus Kuenenia stuttgartiensis|Rep: Putative
uncharacterized protein - Candidatus Kuenenia
stuttgartiensis
Length = 284
Score = 87.4 bits (207), Expect = 3e-16
Identities = 67/185 (36%), Positives = 97/185 (52%), Gaps = 6/185 (3%)
Frame = +2
Query: 95 LSSGGNIPVVALGTW-LGHRPKGKVVQVTNDTEQ--AVIYALEAGYTHIDTAYKYG---I 256
LS+ IPV+ LGTW +G G T D E A+ A++ G THID A Y
Sbjct: 6 LSNNIKIPVIGLGTWTIGG---GDEADTTYDKENISAIKTAIKLGITHIDNAEAYAQGHS 62
Query: 257 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
E+ VGRA+ GL R+S+FIT+K+ + + ++ + + SL+ LN +Y+DLYLIH
Sbjct: 63 EELVGRAIV-----GLDRKSLFITSKVSPEHLSYDNLLASAKGSLQRLNTDYIDLYLIHA 117
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
P + +DFL ++ K L + IG+SNF+ +QI+ K A Q
Sbjct: 118 PNPDIPIQETMKAMDFL------VEQK---LVRCIGVSNFSVDQIKEAQKYTKNKIVANQ 168
Query: 617 IELNL 631
IE NL
Sbjct: 169 IEYNL 173
>UniRef50_A6LZ55 Cluster: 2,5-didehydrogluconate reductase; n=1;
Clostridium beijerinckii NCIMB 8052|Rep:
2,5-didehydrogluconate reductase - Clostridium
beijerinckii NCIMB 8052
Length = 289
Score = 87.0 bits (206), Expect = 3e-16
Identities = 51/147 (34%), Positives = 77/147 (52%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 361
D E AV A++ GY H DTA YG E +G A+ K + RE FIT+K+WN+ H E
Sbjct: 31 DFETAVGEAIKIGYRHFDTAKIYGNEKDLGLAIEKS---QIPREEFFITSKVWNTDHGYE 87
Query: 362 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 541
A ++ + LN+EY+D+YLIH+ + +L+TW M + G K I
Sbjct: 88 ATKKAFEQTCKKLNVEYLDMYLIHFASSY-----------YLETWHAMEELYLQGKIKVI 136
Query: 542 GISNFNQEQIQRIIDSGLEKPSALQIE 622
G++NF + ++ ++ P QIE
Sbjct: 137 GVANFQIQHLEELMKHSRITPMINQIE 163
>UniRef50_A7BES9 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 282
Score = 86.6 bits (205), Expect = 4e-16
Identities = 63/178 (35%), Positives = 92/178 (51%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
+ L++G IP V LGT+L +D + AV YAL+ YT IDTA Y E V
Sbjct: 4 ITLNNGITIPQVGLGTYLLE---------PDDAQSAVTYALDNDYTLIDTANVYVNERAV 54
Query: 269 GRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
GR + + R+ IF+ TKLW S+ ER A+ ++LE L +Y+DL ++H P
Sbjct: 55 GRGMR---ASSKARDEIFLETKLWPSFFERAS---AVEETLERLGTDYIDLMILHQPAG- 107
Query: 449 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
D + +R + A K G ++IG+SNF+ Q QRI+D P+ Q+E
Sbjct: 108 ----------DTVAGYRILEKAHKEGKIRAIGLSNFDVAQTQRILDECEVVPTINQVE 155
>UniRef50_A6WDZ5 Cluster: Aldo/keto reductase; n=5; Bacteria|Rep:
Aldo/keto reductase - Kineococcus radiotolerans SRS30216
Length = 343
Score = 86.2 bits (204), Expect = 6e-16
Identities = 53/195 (27%), Positives = 91/195 (46%), Gaps = 11/195 (5%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGI 256
+VP +L G +P + +GT+ R V AV A+ AGY +D A YG
Sbjct: 12 LVPRRELRGGATVPAIGIGTFGSDRYSPAEVAA------AVAGAVAAGYRLVDCAAVYGN 65
Query: 257 EDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHW 436
E QVG AL + G+ R+ +F+ +K+WN H + ++ +SL +L L+++D +HW
Sbjct: 66 EAQVGEALAGAVAGGVDRDELFVVSKVWNDAHAPADAVASVHRSLRDLRLDHLDAVFVHW 125
Query: 437 PI-----AMFENDTL------LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRII 583
P M + D D+ +L W + GL + +G SN ++ ++
Sbjct: 126 PFPNHHPPMADTDARDPRARPYDHDAYLALWGALEGLVDSGLVRHLGTSNTTVAKLDLLL 185
Query: 584 DSGLEKPSALQIELN 628
P+ ++EL+
Sbjct: 186 RDARIPPALNEMELH 200
>UniRef50_A3LWP0 Cluster: Aldo/keto reductase; n=7;
Saccharomycetales|Rep: Aldo/keto reductase - Pichia
stipitis (Yeast)
Length = 323
Score = 86.2 bits (204), Expect = 6e-16
Identities = 52/152 (34%), Positives = 80/152 (52%), Gaps = 5/152 (3%)
Frame = +2
Query: 137 WLGH-RPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRE 313
WL RP+ + +T + +++ ALE GY HIDTA Y +V A+ K G+ RE
Sbjct: 35 WLKKGRPEEEQNTLTTELVDSILLALENGYNHIDTAEVYTTHPEVAAAVKKS---GIARE 91
Query: 314 SIFITTKLWNSYHEREQVIPA----LRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVD 481
+FITTK + + + ++L+ L +YVDL+LIH P F + +
Sbjct: 92 DLFITTKYTPGFRTFPAISSGPTEFIDRALKELETDYVDLFLIHSP---FFEEKVSRGQT 148
Query: 482 FLDTWRGMIDAKKLGLTKSIGISNFNQEQIQR 577
W +IDAKK G + IG+SNF++E ++R
Sbjct: 149 LESAWAEVIDAKKAGKVRHIGVSNFSKEHLER 180
>UniRef50_Q5UX52 Cluster: Oxidoreductase aldo/keto reductase family;
n=1; Haloarcula marismortui|Rep: Oxidoreductase
aldo/keto reductase family - Haloarcula marismortui
(Halobacterium marismortui)
Length = 274
Score = 86.2 bits (204), Expect = 6e-16
Identities = 58/162 (35%), Positives = 83/162 (51%), Gaps = 1/162 (0%)
Frame = +2
Query: 104 GGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 280
G ++P + LGTW Q+T + + V AL GY HIDTA YG E QVG +
Sbjct: 8 GTSVPALGLGTW----------QLTGQSCRETVETALGMGYRHIDTAQAYGNERQVGLGM 57
Query: 281 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 460
+ + RE +F+TTKL S + V + R+SL L +Y+DL LIHWP N
Sbjct: 58 D---AAAVDREDVFLTTKLDGSNRDERSVRRSTRESLNKLGTDYLDLLLIHWP-----NT 109
Query: 461 TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
+ ++ +T M D + GL + IG+SNF+ + R D
Sbjct: 110 PWMASLS--ETLGAMNDVVEEGLVRHIGVSNFSPSLLDRARD 149
>UniRef50_Q4PHK0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 355
Score = 85.8 bits (203), Expect = 8e-16
Identities = 63/213 (29%), Positives = 105/213 (49%), Gaps = 32/213 (15%)
Frame = +2
Query: 86 TLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQA----------VIYALEAGYTHI- 232
T +L++G IPV+ LGTW G+V + +A + L GY +
Sbjct: 13 TFKLNTGAEIPVIGLGTW--QSAPGEVAKAVESAIKAGYRHIVSMLTSLLTLTLGYVALH 70
Query: 233 ---------DTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRK 385
D A+ YG E++VG+ + + G+ R +F+TTK+W +YH + + L +
Sbjct: 71 PLYIPFLAKDAAWIYGNENEVGQGIK---ASGVPRSELFVTTKIWCTYHRQPEA--CLDE 125
Query: 386 SLENLNLEYVDLYLIHWPIAMFEN-DTLL----DNVDFLD-------TWRGMIDAKKLGL 529
SL+ L L+YVDL L+HWP+ + + D + D +D TW M G
Sbjct: 126 SLQRLGLDYVDLLLVHWPVPLVKRGDEKIPLNEDGSRAIDRDWSPEQTWELMEKLPATGK 185
Query: 530 TKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
TK+IG+SN++ + +++ P+A Q+EL+
Sbjct: 186 TKAIGVSNWSIAFLDKLLAKAKIVPAANQVELH 218
>UniRef50_A7SGW6 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 264
Score = 85.4 bits (202), Expect = 1e-15
Identities = 51/155 (32%), Positives = 84/155 (54%)
Frame = +2
Query: 164 VVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWN 343
V ++ E ++AL+ GY +DTA Y E +VG A+ K GLKRE I++TTKL
Sbjct: 28 VFRLETGCEDVCLFALKNGYRMLDTADIYQNEKEVGSAVRKS---GLKREDIYVTTKLKP 84
Query: 344 SYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKL 523
S + ++S++ L++ YVDL+LIH P N+ + + ++ K+
Sbjct: 85 SEEGHSNALKYAKESIKKLDIGYVDLFLIHTPRP--------GNI--IAAYDALLTLKEE 134
Query: 524 GLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
GL +S+G+SNF ++ + +G P+ QIE+N
Sbjct: 135 GLIRSVGVSNFGVHHLEELRKAGCRTPAINQIEIN 169
>UniRef50_Q5FLI5 Cluster: Aldehyde reductase; n=2; Bacteria|Rep:
Aldehyde reductase - Lactobacillus acidophilus
Length = 278
Score = 85.0 bits (201), Expect = 1e-15
Identities = 54/148 (36%), Positives = 79/148 (53%)
Frame = +2
Query: 188 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQV 367
+Q V LE GY +DTA YG E VG A+ K S + RE IFIT+K+W + +
Sbjct: 30 QQVVEDGLEVGYRLVDTAQIYGNEQAVGDAI--KHSN-VPREDIFITSKIWVDDYGYDNT 86
Query: 368 IPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGI 547
+ A S++ L L+Y+DLYLIH P D+ TWR + + G ++IG+
Sbjct: 87 LKAFDDSMKKLQLDYIDLYLIHKPYN-----------DYYGTWRALERLYQEGRIRAIGV 135
Query: 548 SNFNQEQIQRIIDSGLEKPSALQIELNL 631
S+F E++ +I KP+ QIE N+
Sbjct: 136 SSFWNERLADLITFNDVKPAVNQIETNV 163
>UniRef50_Q54NR2 Cluster: Aldo-keto reductase; n=3; Dictyostelium
discoideum AX4|Rep: Aldo-keto reductase - Dictyostelium
discoideum AX4
Length = 305
Score = 85.0 bits (201), Expect = 1e-15
Identities = 50/160 (31%), Positives = 82/160 (51%), Gaps = 10/160 (6%)
Frame = +2
Query: 179 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEG-------LKRESIFITTKL 337
ND E + LE GY IDTA Y E+++G+ L + ++ +KRE +FIT+K
Sbjct: 38 NDIENIIKVGLENGYRRIDTASMYNNEERIGKVLNEMVTKNDGLDGKKIKREDLFITSKC 97
Query: 338 WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP-IAMFENDTLLDNVDFLDTWRGMIDA 514
E + A SL+ L L+Y+D YLIHWP + + +++ TWR +
Sbjct: 98 SFMEQGYENALKAFESSLKKLQLDYLDCYLIHWPGVKGLDGSDSGNSIQRAQTWRALEKL 157
Query: 515 KKLGLTKSIGISNFNQEQIQRIIDS-GLE-KPSALQIELN 628
+ +SIG+SN+ + ++ S L+ KP+ Q+E +
Sbjct: 158 YQDKKVRSIGVSNYTINHLTELLSSPNLQIKPAINQVEFH 197
>UniRef50_A1RB46 Cluster: 2,5-diketo-D-gluconate reductase; n=1;
Arthrobacter aurescens TC1|Rep: 2,5-diketo-D-gluconate
reductase - Arthrobacter aurescens (strain TC1)
Length = 273
Score = 84.6 bits (200), Expect = 2e-15
Identities = 58/180 (32%), Positives = 88/180 (48%), Gaps = 1/180 (0%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVG 271
Q S+G +P + LGT G RP D + V +AL+ GY DTA YG E +G
Sbjct: 3 QHSAGTALPAITLGT--GLRPP-------TDVYRLVGWALDMGYRSFDTAALYGTEAAIG 53
Query: 272 RALTKKFSEGLKRESIFITTKL-WNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAM 448
RA+ G+ R +FIT K+ N Y R +V A+ +SLE L + D+ + HWP+ M
Sbjct: 54 RAIR---DSGIDRRELFITVKVRGNEYGSRARVHQAIERSLEALGTSFADMVVPHWPLPM 110
Query: 449 FENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELN 628
T+ M+DA+ GL + +G+SN + ++ + E P Q+ L+
Sbjct: 111 VR--------ALPSTFAQMLDARSEGLVRGVGLSNASSAMVRAVRTETGEWPVVNQLHLS 162
>UniRef50_Q979I4 Cluster: Aldo / keto reductase; n=3; Archaea|Rep:
Aldo / keto reductase - Thermoplasma volcanium
Length = 288
Score = 84.6 bits (200), Expect = 2e-15
Identities = 50/132 (37%), Positives = 77/132 (58%)
Frame = +2
Query: 191 QAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVI 370
QA+ A++AG T IDTA YG ED V +A+ EG RE +FI TK+W ++ ++VI
Sbjct: 50 QAIRTAIDAGVTLIDTAEIYGSEDLVAKAI-----EGHNREELFIATKVWINHLRYDKVI 104
Query: 371 PALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGIS 550
A + SL LN +YVDLY IH+P + +T++ M GL K IG+S
Sbjct: 105 KACKASLSRLNTKYVDLYQIHFP---------SPTANLQETFKAMEKLVDDGLVKFIGVS 155
Query: 551 NFNQEQIQRIID 586
NF++ ++++ ++
Sbjct: 156 NFSRGKLEKSME 167
>UniRef50_Q9A2X8 Cluster: Oxidoreductase, aldo/keto reductase
family; n=3; Caulobacter|Rep: Oxidoreductase, aldo/keto
reductase family - Caulobacter crescentus (Caulobacter
vibrioides)
Length = 279
Score = 84.2 bits (199), Expect = 2e-15
Identities = 57/167 (34%), Positives = 85/167 (50%), Gaps = 1/167 (0%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIY-ALEAGYTHIDTAYKYG 253
+VP ++ S +P + GTW Q+ N T ++ ALE GY HIDTA YG
Sbjct: 4 LVPAVR-SGDVLMPALGFGTW----------QLENGTAVPLVEKALEIGYRHIDTAQIYG 52
Query: 254 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
E VG A+ + G+KR+ IF+TTK+W + + KSLE L ++ VDL L+H
Sbjct: 53 NERDVGAAIR---NSGVKRDEIFLTTKVWIDQFADGDLQRSAEKSLEKLGVDQVDLLLLH 109
Query: 434 WPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQ 574
WP V +T + + + G T++IG+SNF Q++
Sbjct: 110 WP---------KPEVPLAETLKALNAVRAKGWTRAIGLSNFPSAQLE 147
>UniRef50_Q2CAL9 Cluster: 2,5-didehydrogluconate reductase; n=2;
Oceanicola granulosus HTCC2516|Rep:
2,5-didehydrogluconate reductase - Oceanicola granulosus
HTCC2516
Length = 275
Score = 84.2 bits (199), Expect = 2e-15
Identities = 48/125 (38%), Positives = 72/125 (57%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 361
D A++ ALE GY H+DTA Y E +VG A+ + GL RE++F+TTK+ +
Sbjct: 26 DGISAILCALETGYRHLDTAQDYDTEAEVGEAIRRA---GLPREALFVTTKVRPANFGPG 82
Query: 362 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 541
++P++ +SLE + L+ DL LIHWP E L D + L +A+ GLT+ +
Sbjct: 83 DLVPSVARSLETMGLDRADLVLIHWPAPNGER-PLSDYIPQL------AEARAQGLTRHV 135
Query: 542 GISNF 556
G+SNF
Sbjct: 136 GVSNF 140
>UniRef50_Q17DN1 Cluster: Aldo-keto reductase; n=1; Aedes
aegypti|Rep: Aldo-keto reductase - Aedes aegypti
(Yellowfever mosquito)
Length = 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 62/184 (33%), Positives = 93/184 (50%), Gaps = 2/184 (1%)
Frame = +2
Query: 83 PTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIED 262
P ++L++G +PV+ LGTWL +G +A+ A++AGY HIDTAY Y E
Sbjct: 6 PMVKLNNGLEMPVLGLGTWLSKEGEGV---------EAIKAAIDAGYRHIDTAYFYQNEK 56
Query: 263 QVGRALTKKFSEGLK-RESIFITTKLWNSYHEREQVIP-ALRKSLENLNLEYVDLYLIHW 436
+VG A+ K EG+ RE +F+TTK + + + ++P L+ +++Y+D
Sbjct: 57 EVGEAIRAKIEEGVVCREDLFVTTKFID--WDTKNLMPYDADGKLQFSDVDYID------ 108
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
TW+ M K G KSIG+SNFN EQI R++ KP Q
Sbjct: 109 ------------------TWKAMEKLLKTGKVKSIGVSNFNSEQITRLLAECEIKPVTNQ 150
Query: 617 IELN 628
+E N
Sbjct: 151 VECN 154
>UniRef50_Q9HM42 Cluster: Alcohol dehydrogenase related protein;
n=1; Thermoplasma acidophilum|Rep: Alcohol dehydrogenase
related protein - Thermoplasma acidophilum
Length = 284
Score = 84.2 bits (199), Expect = 2e-15
Identities = 56/178 (31%), Positives = 90/178 (50%)
Frame = +2
Query: 101 SGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRAL 280
+G + V+ +GTW + + V+ ++ YAL+ G IDTA YG ED VG A+
Sbjct: 12 TGRKVSVIGVGTWSLEGSRSENVR-------SIRYALDHGVNFIDTAEMYGTEDIVGEAI 64
Query: 281 TKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEND 460
+G +RE +FI TK+W ++ V+ + +SL+ L +YVDLY +HWP
Sbjct: 65 -----KGYRREDLFIATKVWPTHFAYHDVLKSCEESLKKLGTDYVDLYQLHWP------- 112
Query: 461 TLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIELNLN 634
+V +T M G + IGISNF+ ++++ + S L K + +L N
Sbjct: 113 --NPSVSIKETMSAMEKLVDEGRIRYIGISNFSVKEMKEAM-SALAKYRIVSNQLEYN 167
>UniRef50_Q2BBN7 Cluster: YvgN; n=1; Bacillus sp. NRRL B-14911|Rep:
YvgN - Bacillus sp. NRRL B-14911
Length = 268
Score = 83.8 bits (198), Expect = 3e-15
Identities = 59/185 (31%), Positives = 91/185 (49%), Gaps = 4/185 (2%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGT-WLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQ 265
+ L++G +P+V GT G +TN+ + + A+E GY ID A Y E+
Sbjct: 4 ITLNNGLEMPIVGTGTNTYGKENNDYNGDLTNEIPE-LASAIELGYRSIDAAIMYRNEEL 62
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYH---EREQVIPALRKSLENLNLEYVDLYLIHW 436
VG L + + RE FITTK+ S +E A+ SL+N +Y+DL LIH+
Sbjct: 63 VGSVLAES---KVPREEFFITTKIPASEEYISSKEATRAAIDNSLKNFQTDYLDLLLIHF 119
Query: 437 PIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQ 616
PI D V +TW + + G K+IG+SNF + + + + KP+ Q
Sbjct: 120 PIE--------DKVQLKNTWEVFEEYYEAGKLKAIGVSNFEENHLDELKEFAKVKPAVNQ 171
Query: 617 IELNL 631
I++NL
Sbjct: 172 IQINL 176
>UniRef50_A7TLC4 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 313
Score = 83.4 bits (197), Expect = 4e-15
Identities = 63/182 (34%), Positives = 88/182 (48%), Gaps = 4/182 (2%)
Frame = +2
Query: 95 LSSGGNIP---VVALGTWLGHRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIED 262
L++G IP ++ GT RP G +++ + + YAL G HID A YG
Sbjct: 10 LNNGNQIPSISIIGTGTRWFKRP-GSEHTFSDELVEQIKYALSLPGIIHIDAAECYGTYP 68
Query: 263 QVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
++ +AL K+ S+ R IFIT K I L L+ L L+YVDLYLIH P
Sbjct: 69 ELAKAL-KESSK--PRSEIFITDKYSTQTKFTNDPIEGLNTGLKTLGLDYVDLYLIHSP- 124
Query: 443 AMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
F + ++ W+ M K G KSIG+SNF+ + I+ I+ KP QIE
Sbjct: 125 --FFDPEFKGSLTLEKVWKDMETLYKEGKAKSIGVSNFSVKNIEEILKIAGIKPQVNQIE 182
Query: 623 LN 628
N
Sbjct: 183 FN 184
>UniRef50_Q14LA8 Cluster: Putative aldo/keto reductase
oxidoreductase protein; n=1; Spiroplasma citri|Rep:
Putative aldo/keto reductase oxidoreductase protein -
Spiroplasma citri
Length = 263
Score = 83.0 bits (196), Expect = 5e-15
Identities = 54/148 (36%), Positives = 80/148 (54%), Gaps = 1/148 (0%)
Frame = +2
Query: 188 EQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF-SEGLKRESIFITTKLWNSYHEREQ 364
E+A+I AL+ GY IDTA Y E+ VGRA+ K S +RE I I TK+W E
Sbjct: 18 EEAIINALQNGYKIIDTAKVYQNEEIVGRAIKKYLNSNNQRREDIIIETKIWCDDVEAGN 77
Query: 365 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 544
A+ +SL+ LN+ Y+D+ LIH P F T+ V+ ++ K GL +G
Sbjct: 78 TTNAVLESLKRLNVTYLDIVLIHRPNLNFYK-TIKAYVE-------LLQCKAKGLINVVG 129
Query: 545 ISNFNQEQIQRIIDSGLEKPSALQIELN 628
+SNF+++ I+ + + P+ QIE N
Sbjct: 130 VSNFDKDMIEILFEETGAYPNLNQIEFN 157
>UniRef50_A5DRJ6 Cluster: Putative uncharacterized protein; n=4;
Pichia guilliermondii|Rep: Putative uncharacterized
protein - Pichia guilliermondii (Yeast) (Candida
guilliermondii)
Length = 287
Score = 83.0 bits (196), Expect = 5e-15
Identities = 62/183 (33%), Positives = 92/183 (50%), Gaps = 5/183 (2%)
Frame = +2
Query: 95 LSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGR 274
L +G IP +G +L + T V AL+ GY IDTA +Y E + G
Sbjct: 12 LLNGSRIPACGVGVYL---------LPASQTAGIVEKALDVGYRLIDTAQEYENERETGE 62
Query: 275 ALTKKFSEGL--KRESIFITTKLWNSYHEREQVIPALRKSLENL-NLEYVDLYLIHWPIA 445
+ + KRE + TTK+ N ++ +L++SL + +LEY+DL LIH
Sbjct: 63 GIKAWLGKDKNNKREDVLYTTKITNLNQGYDRTWRSLKESLNKVKHLEYIDLVLIH---- 118
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID-SGLE-KPSALQI 619
D L D ++TW+ + +A G+ KSIG+SNF + IQ + D GL+ KP QI
Sbjct: 119 ----DPLSDKKTRIETWKALQEAVDSGMVKSIGVSNFGKHHIQELYDWEGLKYKPIVNQI 174
Query: 620 ELN 628
EL+
Sbjct: 175 ELS 177
>UniRef50_Q8EUH6 Cluster: Oxidoreductase; n=1; Mycoplasma
penetrans|Rep: Oxidoreductase - Mycoplasma penetrans
Length = 285
Score = 82.6 bits (195), Expect = 7e-15
Identities = 60/184 (32%), Positives = 98/184 (53%), Gaps = 4/184 (2%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIEDQ 265
++L++G ++P++ LG + + +G+ + E +I A++ GY IDTA Y E+
Sbjct: 4 IKLANGLHMPIIGLGVY---KAEGE------NCENTIIKAIDDYGYRMIDTAQVYFNEEF 54
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VG A+ + +KRE IFITTK+W S + + ++ KSL+ L Y+DL L+H P
Sbjct: 55 VGNAIKQT---KIKREDIFITTKVWISNYGYNNTMYSISKSLKKLQTNYIDLVLLHQPFG 111
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE---KPSALQ 616
D+ W+ + K G+ K+IG+SNF + R++D L KP Q
Sbjct: 112 -----------DYYSAWKALEVLYKKGIVKAIGVSNF---EADRLVDFCLHVDVKPVINQ 157
Query: 617 IELN 628
IEL+
Sbjct: 158 IELH 161
>UniRef50_Q11BF8 Cluster: Aldo/keto reductase; n=12; Bacteria|Rep:
Aldo/keto reductase - Mesorhizobium sp. (strain BNC1)
Length = 308
Score = 81.8 bits (193), Expect = 1e-14
Identities = 49/150 (32%), Positives = 79/150 (52%)
Frame = +2
Query: 179 NDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 358
++T AV AL GY HIDTA YG E +VG + + G+ R+ +FI TK+W S +
Sbjct: 42 DETTAAVEEALRLGYRHIDTAAAYGNEREVGEGIRRA---GIARDEVFIETKIWISDYGY 98
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 538
++ + A KS L ++ +DL L+H P+ + T L +R + G ++
Sbjct: 99 DETLHAFDKSAGKLGVDQIDLLLLHQPLPSAFDRT-------LGAYRALEKLLADGKVRA 151
Query: 539 IGISNFNQEQIQRIIDSGLEKPSALQIELN 628
IG+SNF E + R++ P+ QIE++
Sbjct: 152 IGVSNFMPEHLTRLLTETSIVPAVNQIEVH 181
>UniRef50_Q07551 Cluster: NADPH-dependent alpha-keto amide
reductase; n=4; Saccharomycetales|Rep: NADPH-dependent
alpha-keto amide reductase - Saccharomyces cerevisiae
(Baker's yeast)
Length = 312
Score = 81.8 bits (193), Expect = 1e-14
Identities = 57/181 (31%), Positives = 91/181 (50%), Gaps = 3/181 (1%)
Frame = +2
Query: 95 LSSGGNIPVVAL-GTWLG-HRPKGKVVQVTNDTEQAVIYALEA-GYTHIDTAYKYGIEDQ 265
L++G IP +A+ GT ++ + +N + ++YAL+ G HID A Y +
Sbjct: 10 LNNGNKIPAIAIIGTGTRWYKNEETDATFSNSLVEQIVYALKLPGIIHIDAAEIYRTYPE 69
Query: 266 VGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
VG+AL+ +E R +IF+T K + L +L+ + +YVDLYL+H P
Sbjct: 70 VGKALS--LTEK-PRNAIFLTDKYSPQIKMSDSPADGLDLALKKMGTDYVDLYLLHSPFV 126
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIEL 625
E ++ + + W+ M K G K+IG+SNF E +QRI+ KP QIE
Sbjct: 127 SKE----VNGLSLEEAWKDMEQLYKSGKAKNIGVSNFAVEDLQRILKVAEVKPQVNQIEF 182
Query: 626 N 628
+
Sbjct: 183 S 183
>UniRef50_Q76L36 Cluster: Conjugated polyketone reductase C2; n=1;
Candida parapsilosis|Rep: Conjugated polyketone
reductase C2 - Candida parapsilosis (Yeast)
Length = 307
Score = 81.4 bits (192), Expect = 2e-14
Identities = 53/168 (31%), Positives = 82/168 (48%), Gaps = 4/168 (2%)
Frame = +2
Query: 62 TSAELIVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTA 241
T + L+ T + SG I + ALGT + + V+ + ++ L+ G+ HIDTA
Sbjct: 2 TQSNLLPKTFRTKSGKEISI-ALGTGTKWKQAQTINDVSTELVDNILLGLKLGFRHIDTA 60
Query: 242 YKYGIEDQVGRALTKKFSEGLKRESIFITTKL---WNSYHE-REQVIPALRKSLENLNLE 409
Y + +VG AL + + RE I++TTK W S + ++ K+L L ++
Sbjct: 61 EAYNTQKEVGEALKR---TDVPREDIWVTTKYSPGWGSIKAYSKSPSDSIDKALAQLGVD 117
Query: 410 YVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISN 553
YVDL+LIH P E W +++AKK G + IGISN
Sbjct: 118 YVDLFLIHSPFFTTEQ---THGYTLEQAWEALVEAKKAGKVREIGISN 162
>UniRef50_Q4WI64 Cluster: Aldehyde reductase, putative; n=22;
Pezizomycotina|Rep: Aldehyde reductase, putative -
Aspergillus fumigatus (Sartorya fumigata)
Length = 295
Score = 81.0 bits (191), Expect = 2e-14
Identities = 50/140 (35%), Positives = 77/140 (55%), Gaps = 3/140 (2%)
Frame = +2
Query: 185 TEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQ 364
TE+A + ALE GY HID+A Y E + A+ K G+ R IF TTK+ S E+
Sbjct: 46 TEKATLKALETGYRHIDSAKYYANEKECAVAMKKS---GIDRSKIFFTTKVPASSMSYEK 102
Query: 365 VIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIG 544
A+ +S+ +L Y+DL L+H P E L WR +++A+K G +SIG
Sbjct: 103 AKEAIEQSVAATDLGYIDLILLHAPYGGKEGR--------LGAWRALVEAQKAGHVRSIG 154
Query: 545 ISNF---NQEQIQRIIDSGL 595
+SN+ + E+++ I+SG+
Sbjct: 155 VSNYGIHHLEELEEYINSGV 174
>UniRef50_Q5V6N9 Cluster: Alcohol dehydrogenase; n=2;
Halobacteriaceae|Rep: Alcohol dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 667
Score = 81.0 bits (191), Expect = 2e-14
Identities = 47/172 (27%), Positives = 85/172 (49%), Gaps = 25/172 (14%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 361
D ++ AL+AGY +D+A YG E ++GR L + +R +FI K+W + H R+
Sbjct: 395 DRADSIAAALDAGYRLLDSAELYGNEHRIGRILAAPGAPDRRR--VFILGKVWRTNHRRK 452
Query: 362 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTL------------------------- 466
++ A R SL+ L ++ D Y +HWP A+ +L
Sbjct: 453 HMLTACRSSLDELGIDAFDCYALHWPEALAHRGSLTRLAEKSVARQEALTFPKNDRGDIE 512
Query: 467 LDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQIE 622
D+V W + + G T+++G+ N +Q Q++ +I++G +P+ +Q+E
Sbjct: 513 TDSVSLQRAWENLEALHERGWTRTLGLCNVSQTQLETVIETGTVRPALVQVE 564
>UniRef50_Q03X85 Cluster: Aldo/keto reductase of diketogulonate
reductase family; n=1; Leuconostoc mesenteroides subsp.
mesenteroides ATCC 8293|Rep: Aldo/keto reductase of
diketogulonate reductase family - Leuconostoc
mesenteroides subsp. mesenteroides (strain ATCC 8293
/NCDO 523)
Length = 288
Score = 80.2 bits (189), Expect = 4e-14
Identities = 55/154 (35%), Positives = 78/154 (50%), Gaps = 5/154 (3%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGL-KRESIFITTKLWNSYHER 358
+T+QAV+ A+ AGY IDTA YG E + G+ + + + + RE +F+TTKLW S
Sbjct: 26 ETKQAVVDAINAGYRSIDTARVYGNEAETGQGVNEAIANAVVAREELFLTTKLWLSEFSY 85
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 538
E A+ SL+ L +Y DL L+H P D ++ + +A+ G KS
Sbjct: 86 EAAKGAIDDSLKKLGTDYADLILLHQPYG-----------DVYGAYKALAEAQADGKVKS 134
Query: 539 IGISNFNQ----EQIQRIIDSGLEKPSALQIELN 628
IGISNF E I+ I L P QIE +
Sbjct: 135 IGISNFYPAKFVEFIKVIKTMNLPVPQIDQIEFH 168
>UniRef50_A7D6Q0 Cluster: Aldo/keto reductase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Aldo/keto reductase -
Halorubrum lacusprofundi ATCC 49239
Length = 309
Score = 80.2 bits (189), Expect = 4e-14
Identities = 52/164 (31%), Positives = 82/164 (50%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+PT L SG +P + LGT+ + +V AL +GYTHIDTA Y E
Sbjct: 34 IPTQTLPSGDTLPALGLGTY---------ALDDDQIADSVRAALSSGYTHIDTAEGYHNE 84
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
+ +G L + R+ +F+T+K+ E +I + SLE L +Y+DLYLIHWP
Sbjct: 85 EAIGEVLAE-----YDRDDVFLTSKVLAKNLGYESLIQSCEASLERLETDYLDLYLIHWP 139
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQI 571
N + ++ + M + GL +++G+SNF+ Q+
Sbjct: 140 -----NPA----ISLRESLQAMAELHDRGLVRNVGVSNFSAYQL 174
>UniRef50_A6PR52 Cluster: Aldo/keto reductase; n=1; Victivallis
vadensis ATCC BAA-548|Rep: Aldo/keto reductase -
Victivallis vadensis ATCC BAA-548
Length = 287
Score = 79.8 bits (188), Expect = 5e-14
Identities = 61/190 (32%), Positives = 93/190 (48%), Gaps = 6/190 (3%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKG-KVVQVTNDTEQ--AVIYALEAGYTHIDTAYKY 250
VP L +G IPV+ GTW R G ND A+ + G HIDTA Y
Sbjct: 4 VPWKSLKNGFAIPVLGQGTW---RMGGVDTPDTANDDADIAAIRRGIATGLCHIDTAEMY 60
Query: 251 G---IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDL 421
E+ VG A+ +G++R F+T K+W ++ + V+ A SL+ L +Y+DL
Sbjct: 61 AGGHAEELVGIAMK---GQGIRRADYFLTDKVWKTHLRYDDVLRAAEASLKRLGTDYIDL 117
Query: 422 YLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEK 601
YLIH + +V +T R M K+ G+ + IG+SNF++E+++R +
Sbjct: 118 YLIH---------QVNPDVPEEETIRAMNRLKREGVIRHIGVSNFSEERLKRAQAASDAP 168
Query: 602 PSALQIELNL 631
A Q+ NL
Sbjct: 169 IVANQLHYNL 178
>UniRef50_Q5V663 Cluster: Aldehyde reductase; n=6;
Halobacteriaceae|Rep: Aldehyde reductase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 279
Score = 79.8 bits (188), Expect = 5e-14
Identities = 51/158 (32%), Positives = 78/158 (49%)
Frame = +2
Query: 113 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 292
+P++ LGTW + ++V ALEAGY HIDTA Y E VG +
Sbjct: 17 MPMLGLGTWQN--------EDAEQCAESVRTALEAGYRHIDTAQAYDNESAVGDGIA--- 65
Query: 293 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 472
+ + R+ IF+ TK+W S + VI +SL+ L ++ VDL +HW +E + L
Sbjct: 66 AADVDRDDIFLATKVWISNLSHDDVIETTEESLDKLGVDSVDLLYVHWAAGEYEPEETLP 125
Query: 473 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIID 586
D L RG+ID ++G+SNF ++ +D
Sbjct: 126 AFDEL-VDRGLID--------NVGVSNFEPHHVETAMD 154
>UniRef50_A4YQ04 Cluster: 2,5-diketo-D-gluconate reductase B; n=15;
Proteobacteria|Rep: 2,5-diketo-D-gluconate reductase B -
Bradyrhizobium sp. (strain ORS278)
Length = 273
Score = 79.4 bits (187), Expect = 7e-14
Identities = 56/179 (31%), Positives = 92/179 (51%), Gaps = 1/179 (0%)
Frame = +2
Query: 98 SSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRA 277
+ G +P + LGT+ R +G V + AV AL GY HIDTA Y ED +G A
Sbjct: 6 TQGVRLPKLGLGTF---RMQGTVCR------DAVESALALGYRHIDTAEMYANEDAIGAA 56
Query: 278 LTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFEN 457
L + + RE + +TTK+W + + A SL+ L L++VDLYLIHWP
Sbjct: 57 LA---AAQIAREDLHVTTKVWPENLAPDAIRRAFDTSLKKLRLDFVDLYLIHWPATGMNL 113
Query: 458 DTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSAL-QIELNL 631
++ ++ K+ G T++IG++NF +++ ++ ++ P A Q+E ++
Sbjct: 114 PAAMET---------LMALKQEGRTRAIGVANFTVALLKQAVED-IQAPVACNQVEYHV 162
>UniRef50_P91997 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 297
Score = 79.4 bits (187), Expect = 7e-14
Identities = 56/181 (30%), Positives = 95/181 (52%), Gaps = 4/181 (2%)
Frame = +2
Query: 92 QLSSGGNIPVVALGTWLGHRPKGKVVQVTNDT-EQAVIYALEAGYTHIDTAYKYGIEDQV 268
+L+SG NIP V GT+ +VT + A+ AL AGY DTA Y E ++
Sbjct: 14 KLNSGYNIPFVGFGTY----------KVTGENVPPAIDAALTAGYRMFDTAKYYLNEKEL 63
Query: 269 GRALTKKFSE-GLKRESIFITTKLW-NSYHEREQVIPALRKSLENLNLEYVDLYLIHWPI 442
G AL + GL R +F+T+K + S + RE + +SL++L +Y+D+YL+H+P
Sbjct: 64 GEALKILLPKHGLSRSDVFLTSKFFPESKNCREACRGFVEESLQSLQTDYIDMYLVHYPK 123
Query: 443 AMFENDTLLDNVDFLD-TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
++ ++N ++ + + +AK G +SIG+SN+ ++ + P A Q+
Sbjct: 124 PNDSDNDDVNNAEYRKIAYEVLEEAKAAGKVRSIGVSNYEIVHLEELKTYAKVPPCANQL 183
Query: 620 E 622
E
Sbjct: 184 E 184
>UniRef50_Q09632 Cluster: Probable oxidoreductase ZK1290.5; n=2;
Caenorhabditis|Rep: Probable oxidoreductase ZK1290.5 -
Caenorhabditis elegans
Length = 321
Score = 79.4 bits (187), Expect = 7e-14
Identities = 58/186 (31%), Positives = 100/186 (53%), Gaps = 2/186 (1%)
Frame = +2
Query: 77 IVPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALE-AGYTHIDTAYKYG 253
++PT LS+ +P++ LGT AV+++++ GY IDTA +YG
Sbjct: 1 MIPTTVLSNNVEMPLIGLGT----------THSGGYYHDAVLHSIKKCGYRLIDTAKRYG 50
Query: 254 IEDQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIH 433
+E Q+G A+ K S + RE +F++TKLW ++V A + S E L +Y+D+Y+IH
Sbjct: 51 VEKQLGIAV-KNCS--VPREEMFLSTKLW-PVDCGDEVYNAFQTSCEKLQTDYLDMYMIH 106
Query: 434 WPIAMFENDTLLDNVDFLD-TWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSA 610
P D +++ + + TWR M + +SIG+SN++ E + +++ P A
Sbjct: 107 MPQL---PDWIVNQKETKEKTWRQMELLYEDEHVRSIGVSNYSIEDLDELLEFASILPHA 163
Query: 611 LQIELN 628
Q+EL+
Sbjct: 164 NQVELH 169
>UniRef50_Q8DK16 Cluster: Tlr1054 protein; n=6; Cyanobacteria|Rep:
Tlr1054 protein - Synechococcus elongatus
(Thermosynechococcus elongatus)
Length = 320
Score = 79.0 bits (186), Expect = 9e-14
Identities = 50/160 (31%), Positives = 84/160 (52%)
Frame = +2
Query: 113 IPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKF 292
I + LGTW + ++ ++ + + A+EAG T IDTA YG E R +
Sbjct: 13 ITPLILGTWQAGKRWWVGIE-DEESIRTIRAAVEAGMTTIDTAEVYG-EGHSERIVAA-- 68
Query: 293 SEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLD 472
+ G R+ TK++ ++ + VI A +SL NLN +Y+DLY IHWP F ++
Sbjct: 69 AVGDLRDRCVYATKVFANHLRYKDVIAACERSLRNLNTDYIDLYQIHWPAGSFGSEI--- 125
Query: 473 NVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSG 592
V +T + M++ + G ++IG+SNF++ Q+ + G
Sbjct: 126 -VPIEETMQAMVELQAAGKIRAIGVSNFSRAQLAEAMQYG 164
>UniRef50_A7RUA2 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 246
Score = 78.6 bits (185), Expect = 1e-13
Identities = 49/146 (33%), Positives = 78/146 (53%), Gaps = 1/146 (0%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGI-EDQVGRALTKKFSEGLKRESIFITTKLWNSYHER 358
DT V ALE GY IDTA Y + E QV +A+ G+ R+ IFI TKL Y
Sbjct: 14 DTLSVVKTALETGYRLIDTAQGYPLSEPQVAKAIA---DSGIPRKDIFIITKLHPRYLGY 70
Query: 359 EQVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKS 538
E + ++ SL L+ +Y+DL+LIH ++ ++W+ M + + G +S
Sbjct: 71 EPTLKSVEMSLRALSTDYIDLFLIHSKTGTWK-----------ESWKAMEELHRQGKIRS 119
Query: 539 IGISNFNQEQIQRIIDSGLEKPSALQ 616
+G+SNFN +++Q +++ SA+Q
Sbjct: 120 LGVSNFNVDELQELVNFATVPVSAVQ 145
>UniRef50_Q2H7A8 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 289
Score = 78.6 bits (185), Expect = 1e-13
Identities = 59/181 (32%), Positives = 87/181 (48%)
Frame = +2
Query: 80 VPTLQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIE 259
+P L+L G IP+ T G +G V D +AVI E G+ H+D A YG E
Sbjct: 3 IPLLRLRDGNQIPLDLGDTTFG---QGLV-----DLTKAVI---EKGFYHLDCAEMYGTE 51
Query: 260 DQVGRALTKKFSEGLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWP 439
++V A+ + G+ RE +FIT K+ + E A+ +SL+ + Y DLYLIH P
Sbjct: 52 EEVAIAIKES---GVPREKLFITNKVAQGIDDIEA---AIDQSLQKMQTNYFDLYLIHIP 105
Query: 440 IAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLEKPSALQI 619
+ DF W+ M +K G +SIG+SN+ + I+ + P QI
Sbjct: 106 FFAKSEE------DFQRAWKTMEGIQKAGKARSIGVSNYMRPHIEATLKGATSPPVTNQI 159
Query: 620 E 622
E
Sbjct: 160 E 160
>UniRef50_O14088 Cluster: Xylose and arabinose reductase; n=1;
Schizosaccharomyces pombe|Rep: Xylose and arabinose
reductase - Schizosaccharomyces pombe (Fission yeast)
Length = 275
Score = 78.6 bits (185), Expect = 1e-13
Identities = 57/182 (31%), Positives = 93/182 (51%), Gaps = 2/182 (1%)
Frame = +2
Query: 89 LQLSSGGNIPVVALGTWLGHRPKGKVVQVTNDTEQAVIYALEAGYTHIDTAYKYGIEDQV 268
++L++G P A G+++ +R K +V AL+ GY HID+A Y E
Sbjct: 6 VKLNNGLKCPQFAYGSYMVNRTK---------CFDSVYAALQCGYRHIDSAQMYHNEADC 56
Query: 269 GRALTKKFSE-GLKRESIFITTKLWNSYHEREQVIPALRKSLENLNLEYVDLYLIHWPIA 445
GRA+ K E G KRE I+ T+KL N + + ++ S++ L Y+DL+L+H P
Sbjct: 57 GRAILKFMEETGTKREDIWFTSKL-NDLSGYKSTLSSIDASVKACGLGYIDLFLLHSPYG 115
Query: 446 MFENDTLLDNVDFLDTWRGMIDAKKLGLTKSIGISNFNQEQIQRIIDSGLE-KPSALQIE 622
D +++W+ + + G ++IG+SNF IQ ++DS + P QIE
Sbjct: 116 -----------DRIESWKALEKGVEEGKLRAIGVSNFGPHHIQELLDSHPKIIPCVNQIE 164
Query: 623 LN 628
L+
Sbjct: 165 LH 166
>UniRef50_Q11DV1 Cluster: Aldo/keto reductase; n=10;
Alphaproteobacteria|Rep: Aldo/keto reductase -
Mesorhizobium sp. (strain BNC1)
Length = 274
Score = 78.2 bits (184), Expect = 2e-13
Identities = 49/149 (32%), Positives = 78/149 (52%)
Frame = +2
Query: 182 DTEQAVIYALEAGYTHIDTAYKYGIEDQVGRALTKKFSEGLKRESIFITTKLWNSYHERE 361
+ E+ + ALEAG+ H DTA Y E +GRAL + G +RE +F+TTK+W + +
Sbjct: 25 EVERIIPAALEAGFRHFDTAQIYQNEAALGRALERA---GARREDLFLTTKVWVDNYSAD 81
Query: 362 QVIPALRKSLENLNLEYVDLYLIHWPIAMFENDTLLDNVDFLDTWRGMIDAKKLGLTKSI 541
+ ++ +SLE L ++ VDL L+HWP + ++ L+ K G T+ I
Sbjct: 82 KFAASVDESLEKLKVDQVDLLLLHWPA---HEVPVAAQIERLNA------VKDAGKTRFI 132
Query: 542 GISNFNQEQIQRIIDSGLEKPSALQIELN 628
G+SN N Q++ I Q+EL+
Sbjct: 133 GVSNQNIAQMRESIARSAAPIVTNQVELH 161
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 693,159,741
Number of Sequences: 1657284
Number of extensions: 14899762
Number of successful extensions: 48925
Number of sequences better than 10.0: 500
Number of HSP's better than 10.0 without gapping: 46286
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 48074
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46881492319
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -