Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner11j15f
(683 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q02870 Cluster: DNA excision repair protein haywire; n=... 155 9e-37
UniRef50_P49135 Cluster: TFIIH basal transcription factor comple... 137 2e-31
UniRef50_P19447 Cluster: TFIIH basal transcription factor comple... 136 6e-31
UniRef50_Q4UDK4 Cluster: DNA repair helicase, putative; n=3; Pir... 82 1e-14
UniRef50_UPI0000E4A32D Cluster: PREDICTED: similar to rad25/xp-b... 81 2e-14
UniRef50_A5KDT1 Cluster: DNA repair helicase, putative; n=5; Pla... 77 4e-13
UniRef50_Q5CW21 Cluster: RAD25, helicase involved in DNA repair;... 73 9e-12
UniRef50_Q2H6J9 Cluster: Putative uncharacterized protein; n=1; ... 72 1e-11
UniRef50_UPI00006CFBDB Cluster: DNA repair helicase rad25 family... 69 1e-10
UniRef50_Q8SSK1 Cluster: DNA REPAIR HELICASE RAD25; n=2; Microsp... 65 1e-09
UniRef50_A2E0I3 Cluster: DNA repair helicase rad25 family protei... 63 5e-09
UniRef50_Q98SB9 Cluster: DNA repair helicase; n=1; Guillardia th... 51 3e-05
UniRef50_Q7R1P1 Cluster: GLP_28_32771_35068; n=1; Giardia lambli... 50 4e-05
UniRef50_UPI0000498EE3 Cluster: DNA repair helicase; n=1; Entamo... 49 9e-05
UniRef50_A0DDY7 Cluster: Chromosome undetermined scaffold_47, wh... 49 9e-05
UniRef50_UPI000049A3CE Cluster: DNA repair helicase; n=2; Entamo... 49 1e-04
UniRef50_A4VE44 Cluster: Rad25/xp-B DNA repair helicase; n=2; Te... 46 7e-04
UniRef50_Q580W5 Cluster: DNA repair helicase and transcription f... 46 0.001
UniRef50_A4HH67 Cluster: DNA repair helicase, putative; n=3; Lei... 44 0.003
UniRef50_UPI0000E80B03 Cluster: PREDICTED: hypothetical protein;... 33 6.5
UniRef50_Q4V1L8 Cluster: Putative uncharacterized protein; n=2; ... 33 6.5
UniRef50_Q3AUE9 Cluster: DNA replication and repair protein recF... 33 8.6
>UniRef50_Q02870 Cluster: DNA excision repair protein haywire; n=57;
Eukaryota|Rep: DNA excision repair protein haywire -
Drosophila melanogaster (Fruit fly)
Length = 798
Score = 155 bits (376), Expect = 9e-37
Identities = 68/93 (73%), Positives = 81/93 (87%), Gaps = 1/93 (1%)
Frame = +2
Query: 407 ENDGVPVAAMQDAEKND-QVPEDEFGAKDYRSQMPLKPDNASRPLWVAPNGHIFLEAFSP 583
E++G+P AA ++AE ND Q+ DE+GAKDYRSQM L+PD+ +RPLWVAPNGH+FLE+FSP
Sbjct: 42 ESEGIPGAASKNAETNDEQINTDEYGAKDYRSQMQLRPDHGNRPLWVAPNGHVFLESFSP 101
Query: 584 VYKHAHDFLIAIAEPVCRPPHXXEYXLTAYSLY 682
VYKHAHDFLIAI+EPVCRP H EY LTAYSLY
Sbjct: 102 VYKHAHDFLIAISEPVCRPEHIHEYKLTAYSLY 134
>UniRef50_P49135 Cluster: TFIIH basal transcription factor complex
helicase XPB subunit; n=10; Coelomata|Rep: TFIIH basal
transcription factor complex helicase XPB subunit - Mus
musculus (Mouse)
Length = 783
Score = 137 bits (332), Expect = 2e-31
Identities = 63/94 (67%), Positives = 73/94 (77%)
Frame = +2
Query: 401 NAENDGVPVAAMQDAEKNDQVPEDEFGAKDYRSQMPLKPDNASRPLWVAPNGHIFLEAFS 580
N + VP AA + +++ DE+GAKDYR QMPLK D+ SRPLWVAP+GHIFLEAFS
Sbjct: 32 NESQEAVPSAAGKQVDESS-TKVDEYGAKDYRQQMPLKGDHTSRPLWVAPDGHIFLEAFS 90
Query: 581 PVYKHAHDFLIAIAEPVCRPPHXXEYXLTAYSLY 682
PVYK+A DFL+AIAEPVCRP H EY LTAYSLY
Sbjct: 91 PVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLY 124
>UniRef50_P19447 Cluster: TFIIH basal transcription factor complex
helicase XPB subunit; n=19; Euteleostomi|Rep: TFIIH
basal transcription factor complex helicase XPB subunit
- Homo sapiens (Human)
Length = 782
Score = 136 bits (328), Expect = 6e-31
Identities = 63/94 (67%), Positives = 73/94 (77%)
Frame = +2
Query: 401 NAENDGVPVAAMQDAEKNDQVPEDEFGAKDYRSQMPLKPDNASRPLWVAPNGHIFLEAFS 580
N + VP AA + +++ DE+GAKDYR QMPLK D+ SRPLWVAP+GHIFLEAFS
Sbjct: 32 NDPQEAVPSAAGKQVDESG-TKVDEYGAKDYRLQMPLKDDHTSRPLWVAPDGHIFLEAFS 90
Query: 581 PVYKHAHDFLIAIAEPVCRPPHXXEYXLTAYSLY 682
PVYK+A DFL+AIAEPVCRP H EY LTAYSLY
Sbjct: 91 PVYKYAQDFLVAIAEPVCRPTHVHEYKLTAYSLY 124
>UniRef50_Q4UDK4 Cluster: DNA repair helicase, putative; n=3;
Piroplasmida|Rep: DNA repair helicase, putative -
Theileria annulata
Length = 770
Score = 81.8 bits (193), Expect = 1e-14
Identities = 35/66 (53%), Positives = 49/66 (74%)
Frame = +2
Query: 485 KDYRSQMPLKPDNASRPLWVAPNGHIFLEAFSPVYKHAHDFLIAIAEPVCRPPHXXEYXL 664
+DY S + LK ++ +RPLWV P+G+++LE F+PV K A DF++ IAEPVCRP EY +
Sbjct: 30 RDY-SNLKLKTNHTARPLWVCPDGYLYLELFTPVSKQALDFIVTIAEPVCRPELIHEYQV 88
Query: 665 TAYSLY 682
T +SLY
Sbjct: 89 TVFSLY 94
>UniRef50_UPI0000E4A32D Cluster: PREDICTED: similar to rad25/xp-b
DNA repair helicase, partial; n=2; Strongylocentrotus
purpuratus|Rep: PREDICTED: similar to rad25/xp-b DNA
repair helicase, partial - Strongylocentrotus purpuratus
Length = 308
Score = 81.0 bits (191), Expect = 2e-14
Identities = 46/88 (52%), Positives = 51/88 (57%)
Frame = +2
Query: 419 VPVAAMQDAEKNDQVPEDEFGAKDYRSQMPLKPDNASRPLWVAPNGHIFLEAFSPVYKHA 598
+P A + E D EDEFGAKDYR QM LK D+ VYKHA
Sbjct: 7 IPKNASRQVEDQDAGDEDEFGAKDYRGQMELKKDH--------------------VYKHA 46
Query: 599 HDFLIAIAEPVCRPPHXXEYXLTAYSLY 682
HDFLIAI+EPVCRP + EY LTAYSLY
Sbjct: 47 HDFLIAISEPVCRPENIHEYKLTAYSLY 74
>UniRef50_A5KDT1 Cluster: DNA repair helicase, putative; n=5;
Plasmodium|Rep: DNA repair helicase, putative -
Plasmodium vivax
Length = 900
Score = 77.0 bits (181), Expect = 4e-13
Identities = 34/76 (44%), Positives = 47/76 (61%)
Frame = +2
Query: 455 DQVPEDEFGAKDYRSQMPLKPDNASRPLWVAPNGHIFLEAFSPVYKHAHDFLIAIAEPVC 634
D + + G DY M LK ++ ++PLW+ +G I+LE F+ K A DFLI IAEP+C
Sbjct: 80 DSINIQQRGFHDYSKDMKLKKNHMNKPLWICSDGFIYLEMFNSCSKQASDFLITIAEPIC 139
Query: 635 RPPHXXEYXLTAYSLY 682
RP E+ LT +SLY
Sbjct: 140 RPELIHEFQLTIFSLY 155
>UniRef50_Q5CW21 Cluster: RAD25, helicase involved in DNA repair;
n=2; Cryptosporidium|Rep: RAD25, helicase involved in
DNA repair - Cryptosporidium parvum Iowa II
Length = 835
Score = 72.5 bits (170), Expect = 9e-12
Identities = 39/93 (41%), Positives = 55/93 (59%)
Frame = +2
Query: 404 AENDGVPVAAMQDAEKNDQVPEDEFGAKDYRSQMPLKPDNASRPLWVAPNGHIFLEAFSP 583
+ NDG P+ D++ QV F +DY S++ LK D+ RP+WV P+G I +E F
Sbjct: 17 SSNDGEPLPLACDSQ---QVVLKPF--RDYSSELKLKSDHDKRPIWVFPDGLIIIETFHQ 71
Query: 584 VYKHAHDFLIAIAEPVCRPPHXXEYXLTAYSLY 682
K A +FL+ I+EP+ RP EY LT +SLY
Sbjct: 72 SSKAACEFLVTISEPLSRPELIHEYQLTIFSLY 104
>UniRef50_Q2H6J9 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 808
Score = 72.1 bits (169), Expect = 1e-11
Identities = 35/70 (50%), Positives = 47/70 (67%), Gaps = 1/70 (1%)
Frame = +2
Query: 476 FGAKDYRSQMPLKPDNASRPLWVAPNG-HIFLEAFSPVYKHAHDFLIAIAEPVCRPPHXX 652
F +D+ S +PLKPD+ +RPLW+ P+ + LE F+P+ + A DFLI IAEP RP
Sbjct: 100 FKKRDF-SYLPLKPDHQNRPLWIDPDSCTVVLERFNPLAEQATDFLITIAEPKSRPTFLH 158
Query: 653 EYXLTAYSLY 682
EY LT +SLY
Sbjct: 159 EYALTPHSLY 168
>UniRef50_UPI00006CFBDB Cluster: DNA repair helicase rad25 family
protein; n=1; Tetrahymena thermophila SB210|Rep: DNA
repair helicase rad25 family protein - Tetrahymena
thermophila SB210
Length = 832
Score = 68.9 bits (161), Expect = 1e-10
Identities = 33/65 (50%), Positives = 44/65 (67%)
Frame = +2
Query: 488 DYRSQMPLKPDNASRPLWVAPNGHIFLEAFSPVYKHAHDFLIAIAEPVCRPPHXXEYXLT 667
DY S + LK D RP+ + P+G IFLE F+P+Y+ A+ FLI+I EPV RP ++ LT
Sbjct: 60 DY-STLELKDDYRERPILICPDGIIFLETFNPLYRVAYQFLISIGEPVQRPLSMHKFTLT 118
Query: 668 AYSLY 682
YSLY
Sbjct: 119 KYSLY 123
>UniRef50_Q8SSK1 Cluster: DNA REPAIR HELICASE RAD25; n=2;
Microsporidia|Rep: DNA REPAIR HELICASE RAD25 -
Encephalitozoon cuniculi
Length = 696
Score = 65.3 bits (152), Expect = 1e-09
Identities = 36/82 (43%), Positives = 47/82 (57%), Gaps = 1/82 (1%)
Frame = +2
Query: 440 DAEKNDQV-PEDEFGAKDYRSQMPLKPDNASRPLWVAPNGHIFLEAFSPVYKHAHDFLIA 616
D E N+ V P+ + ++ LK D S P+WV +G I LE F + A DFLIA
Sbjct: 22 DPEMNEVVIPKKATKHQFPYEELVLKEDGESHPIWVNYDGLIILETFRESSRQASDFLIA 81
Query: 617 IAEPVCRPPHXXEYXLTAYSLY 682
IAEP+ RP E+ +TAYSLY
Sbjct: 82 IAEPMSRPLQIHEFQITAYSLY 103
>UniRef50_A2E0I3 Cluster: DNA repair helicase rad25 family protein;
n=2; Trichomonas vaginalis G3|Rep: DNA repair helicase
rad25 family protein - Trichomonas vaginalis G3
Length = 744
Score = 63.3 bits (147), Expect = 5e-09
Identities = 27/64 (42%), Positives = 40/64 (62%)
Frame = +2
Query: 491 YRSQMPLKPDNASRPLWVAPNGHIFLEAFSPVYKHAHDFLIAIAEPVCRPPHXXEYXLTA 670
Y + + ++ +RP V P+GHIF+E FSP Y DF+IAIA+P RP + EY +
Sbjct: 54 YFKDLYILENSDNRPAIVMPDGHIFVETFSPFYSKVVDFIIAIADPCSRPKYVQEYQINP 113
Query: 671 YSLY 682
YS++
Sbjct: 114 YSIF 117
>UniRef50_Q98SB9 Cluster: DNA repair helicase; n=1; Guillardia
theta|Rep: DNA repair helicase - Guillardia theta
(Cryptomonas phi)
Length = 617
Score = 50.8 bits (116), Expect = 3e-05
Identities = 23/51 (45%), Positives = 31/51 (60%)
Frame = +2
Query: 530 RPLWVAPNGHIFLEAFSPVYKHAHDFLIAIAEPVCRPPHXXEYXLTAYSLY 682
+PLW+ +G+I E F+ DFL++I+EPV R EY LT YSLY
Sbjct: 7 KPLWLFNDGYIIFETFNCFLIEIEDFLVSISEPVVRTKLIHEYVLTPYSLY 57
>UniRef50_Q7R1P1 Cluster: GLP_28_32771_35068; n=1; Giardia lamblia
ATCC 50803|Rep: GLP_28_32771_35068 - Giardia lamblia
ATCC 50803
Length = 765
Score = 50.4 bits (115), Expect = 4e-05
Identities = 28/66 (42%), Positives = 39/66 (59%), Gaps = 8/66 (12%)
Frame = +2
Query: 509 LKPDNASRPLWVAPNG-------HI-FLEAFSPVYKHAHDFLIAIAEPVCRPPHXXEYXL 664
LKPD+ RPL V P H+ LE FSP+Y A++FL+++AE RP + EY +
Sbjct: 13 LKPDHHKRPLSVFPYSTNALSADHVVLLETFSPMYDEAYNFLVSLAEAETRPTYVHEYRI 72
Query: 665 TAYSLY 682
T SL+
Sbjct: 73 TEESLH 78
>UniRef50_UPI0000498EE3 Cluster: DNA repair helicase; n=1; Entamoeba
histolytica HM-1:IMSS|Rep: DNA repair helicase -
Entamoeba histolytica HM-1:IMSS
Length = 648
Score = 49.2 bits (112), Expect = 9e-05
Identities = 26/78 (33%), Positives = 41/78 (52%)
Frame = +2
Query: 446 EKNDQVPEDEFGAKDYRSQMPLKPDNASRPLWVAPNGHIFLEAFSPVYKHAHDFLIAIAE 625
+ +D ED + DY M LKP++ P+WV+ N I +E + ++K D+L +A+
Sbjct: 10 DSSDDSLEDMKESTDY--DMRLKPNHPELPMWVSSNLRIVVETSNDMFKEVSDYLSRVAQ 67
Query: 626 PVCRPPHXXEYXLTAYSL 679
R H EY LT S+
Sbjct: 68 VKSRMEHMHEYQLTPTSI 85
>UniRef50_A0DDY7 Cluster: Chromosome undetermined scaffold_47, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_47,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 708
Score = 49.2 bits (112), Expect = 9e-05
Identities = 24/65 (36%), Positives = 42/65 (64%)
Frame = +2
Query: 488 DYRSQMPLKPDNASRPLWVAPNGHIFLEAFSPVYKHAHDFLIAIAEPVCRPPHXXEYXLT 667
DYR+ ++ +++PL ++P+ I +E F+P+Y+ A +FL+ +AEP+ R EY LT
Sbjct: 27 DYRN---IEIVQSNKPLILSPDLGIIVEKFNPLYEIAFEFLMCVAEPISRSELIHEYVLT 83
Query: 668 AYSLY 682
S+Y
Sbjct: 84 QMSMY 88
>UniRef50_UPI000049A3CE Cluster: DNA repair helicase; n=2; Entamoeba
histolytica HM-1:IMSS|Rep: DNA repair helicase -
Entamoeba histolytica HM-1:IMSS
Length = 589
Score = 48.8 bits (111), Expect = 1e-04
Identities = 22/65 (33%), Positives = 35/65 (53%)
Frame = +2
Query: 488 DYRSQMPLKPDNASRPLWVAPNGHIFLEAFSPVYKHAHDFLIAIAEPVCRPPHXXEYXLT 667
D + L+ N S P W+ PNG I +E + Y+ A +F+ I++ C H EY +T
Sbjct: 8 DDSEEFKLQIINTSNPYWICPNGLIIIERDNKNYQIASEFIKKISKVKCLLEHMEEYIIT 67
Query: 668 AYSLY 682
Y++Y
Sbjct: 68 EYTIY 72
>UniRef50_A4VE44 Cluster: Rad25/xp-B DNA repair helicase; n=2;
Tetrahymena thermophila SB210|Rep: Rad25/xp-B DNA repair
helicase - Tetrahymena thermophila SB210
Length = 698
Score = 46.4 bits (105), Expect = 7e-04
Identities = 24/66 (36%), Positives = 37/66 (56%)
Frame = +2
Query: 485 KDYRSQMPLKPDNASRPLWVAPNGHIFLEAFSPVYKHAHDFLIAIAEPVCRPPHXXEYXL 664
+DY S ++ + P + +IF+EAF YK ++FLI IAEPV +P Y +
Sbjct: 35 RDYSSSFEIQENRGFFPETL----YIFVEAFHEKYKEVYEFLIKIAEPVNKPNFIHVYKI 90
Query: 665 TAYSLY 682
T +S+Y
Sbjct: 91 TLFSMY 96
>UniRef50_Q580W5 Cluster: DNA repair helicase and transcription
factor protein, putative; n=3; Trypanosoma|Rep: DNA
repair helicase and transcription factor protein,
putative - Trypanosoma brucei
Length = 938
Score = 45.6 bits (103), Expect = 0.001
Identities = 20/46 (43%), Positives = 25/46 (54%)
Frame = +2
Query: 542 VAPNGHIFLEAFSPVYKHAHDFLIAIAEPVCRPPHXXEYXLTAYSL 679
+ P G IF+ P Y H DFL A EPVCR + EY ++ SL
Sbjct: 3 LGPGGRIFINHGHPAYPHLMDFLTACCEPVCRTLYVSEYTISPSSL 48
>UniRef50_A4HH67 Cluster: DNA repair helicase, putative; n=3;
Leishmania|Rep: DNA repair helicase, putative -
Leishmania braziliensis
Length = 1108
Score = 44.4 bits (100), Expect = 0.003
Identities = 19/46 (41%), Positives = 27/46 (58%)
Frame = +2
Query: 542 VAPNGHIFLEAFSPVYKHAHDFLIAIAEPVCRPPHXXEYXLTAYSL 679
+ +G+IF+E P Y H DFLI+ EPV R H +Y + + SL
Sbjct: 3 IGDSGNIFVEKAHPAYAHVIDFLISCCEPVSRTQHMEQYRMDSSSL 48
>UniRef50_UPI0000E80B03 Cluster: PREDICTED: hypothetical protein;
n=1; Gallus gallus|Rep: PREDICTED: hypothetical protein
- Gallus gallus
Length = 368
Score = 33.1 bits (72), Expect = 6.5
Identities = 14/31 (45%), Positives = 20/31 (64%)
Frame = +2
Query: 506 PLKPDNASRPLWVAPNGHIFLEAFSPVYKHA 598
PL+P +A P+ V P G +FL A P+Y+ A
Sbjct: 327 PLRPSSAFCPVAVLPGGSMFLRAEMPMYRRA 357
>UniRef50_Q4V1L8 Cluster: Putative uncharacterized protein; n=2;
Bacillus cereus|Rep: Putative uncharacterized protein -
Bacillus cereus (strain ZK / E33L)
Length = 160
Score = 33.1 bits (72), Expect = 6.5
Identities = 17/36 (47%), Positives = 24/36 (66%), Gaps = 2/36 (5%)
Frame = +3
Query: 246 QLIVIGEKNKSILPKWGPRRN--SRDMTQKEEVIDQ 347
+LIV G+KNK + P GP+ N +D T KE V+D+
Sbjct: 64 KLIVDGDKNKILDPNQGPQNNLSYKDYTVKEYVVDK 99
>UniRef50_Q3AUE9 Cluster: DNA replication and repair protein recF;
n=1; Chlorobium chlorochromatii CaD3|Rep: DNA
replication and repair protein recF - Chlorobium
chlorochromatii (strain CaD3)
Length = 364
Score = 32.7 bits (71), Expect = 8.6
Identities = 17/62 (27%), Positives = 31/62 (50%), Gaps = 1/62 (1%)
Frame = +2
Query: 446 EKNDQVPEDEFGAKDYRSQMPLKPDN-ASRPLWVAPNGHIFLEAFSPVYKHAHDFLIAIA 622
++N + + G K R+ +PL A W+ +FL +FSP ++H + ++I
Sbjct: 161 QRNALLAQLSSGEKSNRNTLPLWTTQLAELSAWLVERRLLFLTSFSPYFQHYYRYIIKGE 220
Query: 623 EP 628
EP
Sbjct: 221 EP 222
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 602,063,766
Number of Sequences: 1657284
Number of extensions: 11061366
Number of successful extensions: 25256
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 24568
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 25237
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 53305790091
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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