Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner11f03r
(765 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase, cAMP-de... 302 1e-81
BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein. 302 1e-81
M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein ki... 300 4e-81
M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein ki... 299 7e-81
M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein ki... 299 7e-81
BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase, cAMP-de... 299 7e-81
BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase, cAMP-de... 299 7e-81
BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase, cAMP-de... 155 1e-37
X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mR... 155 2e-37
M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein ki... 154 4e-37
BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase, cAMP-de... 132 1e-30
BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein. 132 1e-30
BC070478-1|AAH70478.1| 80|Homo sapiens PRKAR1B protein protein. 110 6e-24
Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein ki... 103 7e-22
Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein ki... 103 7e-22
Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for ... 103 7e-22
EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein. 103 7e-22
D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein ki... 103 7e-22
BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase, cGMP-de... 103 7e-22
AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase, cGMP-de... 103 7e-22
AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase, cGMP-de... 103 7e-22
AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase, cGMP-de... 103 7e-22
AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase, cGMP-de... 103 7e-22
AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase, cGMP-de... 103 7e-22
AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase, cGMP-de... 103 7e-22
AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase, cGMP-de... 103 7e-22
AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase, cGMP-de... 103 7e-22
Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein ki... 96 1e-19
X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent pr... 96 1e-19
D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein ki... 96 1e-19
BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein. 89 2e-17
AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase, cGMP-de... 89 2e-17
AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase, cGMP-de... 89 2e-17
AC006387-1|AAS07389.1| 306|Homo sapiens unknown protein. 81 3e-15
AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN ... 79 2e-14
L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP ... 65 2e-10
BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein. 46 2e-04
BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein. 45 3e-04
U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine nu... 43 0.001
BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide ... 43 0.001
AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein. 43 0.001
BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholip... 42 0.002
BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholip... 42 0.002
AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target ester... 42 0.002
U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel... 42 0.003
L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated c... 42 0.003
L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated c... 42 0.003
AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor CNG-c... 42 0.003
AB209681-1|BAD92918.1| 643|Homo sapiens RAP guanine-nucleotide-... 41 0.004
BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein. 41 0.006
BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for IM... 41 0.006
AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization acti... 41 0.006
AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization activ... 41 0.006
AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein. 41 0.006
BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein. 40 0.007
AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cycl... 40 0.010
AJ133727-1|CAB42630.1| 889|Homo sapiens hyperpolarization-activ... 39 0.017
AJ012582-1|CAB42602.1| 889|Homo sapiens hyperpolarization-activ... 39 0.017
AF065164-1|AAC28444.2| 889|Homo sapiens hyperpolarization-activ... 39 0.017
AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2 prot... 39 0.017
AJ238850-1|CAB52754.1| 1203|Homo sapiens hyperpolarization-activ... 39 0.023
AJ132429-1|CAB42604.1| 1203|Homo sapiens hyperpolarization-activ... 39 0.023
AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1 prot... 39 0.023
U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine nu... 38 0.039
U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine nu... 38 0.039
BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide ... 38 0.039
BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein. 38 0.039
BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein. 38 0.039
BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide ... 38 0.039
AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide... 38 0.039
S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein. 38 0.052
S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-ga... 38 0.052
AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization activ... 38 0.052
AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein. 38 0.052
S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein. 37 0.091
BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated... 37 0.091
BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated... 37 0.091
BC114945-1|AAI14946.1| 423|Homo sapiens C20orf152 protein protein. 34 0.48
AL359828-2|CAI23442.1| 572|Homo sapiens chromosome 20 open read... 34 0.48
AL359828-1|CAI23441.1| 576|Homo sapiens chromosome 20 open read... 34 0.48
AL109965-6|CAI19249.1| 572|Homo sapiens chromosome 20 open read... 34 0.48
AL109965-5|CAI19248.1| 576|Homo sapiens chromosome 20 open read... 34 0.48
AK057454-1|BAB71494.1| 572|Homo sapiens protein ( Homo sapiens ... 34 0.48
M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel... 34 0.64
AL365502-7|CAI14582.1| 1317|Homo sapiens patatin-like phospholip... 32 2.0
AL365502-6|CAI14581.1| 1281|Homo sapiens patatin-like phospholip... 32 2.0
AL365502-5|CAI14579.1| 923|Homo sapiens patatin-like phospholip... 32 2.0
AK125060-1|BAC86036.1| 1317|Homo sapiens protein ( Homo sapiens ... 32 2.0
>BC036828-1|AAH36828.2| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, beta protein.
Length = 381
Score = 302 bits (741), Expect = 1e-81
Identities = 144/179 (80%), Positives = 161/179 (89%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++LIYGTPRAATV+A+T LKLWG+DRDSYRRILMGST+RKR+MY+EFLS+VSILESLEKW
Sbjct: 203 LALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKW 262
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
ERLTVADALEPV F D E IV QGEPG+DFYII EGTA VLQ+R E VEVGRLGPSD
Sbjct: 263 ERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSD 322
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQYNSFVSLSV 213
YFGEIALLL+RPRAATV A GPLKCVKLDR RFERVLG C++ILKRNI +YNSF+SL+V
Sbjct: 323 YFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 381
Score = 67.3 bits (157), Expect = 6e-11
Identities = 47/152 (30%), Positives = 78/152 (51%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
D SY R ++ + + +S+ + L+ ER + DA+ PV+ ET+++QG
Sbjct: 109 DAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQG 168
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
G++FY++ +G V GE V + FGE+AL+ PRAATV+A LK
Sbjct: 169 NEGDNFYVVDQGEVDVY----VNGEWVT--NISEGGSFGELALIYGTPRAATVKAKTDLK 222
Query: 317 CVKLDRARFERVLGLCADILKRNIAQYNSFVS 222
+DR + R+L + + + KR + Y F+S
Sbjct: 223 LWGIDRDSYRRIL-MGSTLRKRKM--YEEFLS 251
>BC026734-1|AAH26734.1| 381|Homo sapiens PRKAR1B protein protein.
Length = 381
Score = 302 bits (741), Expect = 1e-81
Identities = 144/179 (80%), Positives = 161/179 (89%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++LIYGTPRAATV+A+T LKLWG+DRDSYRRILMGST+RKR+MY+EFLS+VSILESLEKW
Sbjct: 203 LALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKW 262
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
ERLTVADALEPV F D E IV QGEPG+DFYII EGTA VLQ+R E VEVGRLGPSD
Sbjct: 263 ERLTVADALEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSD 322
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQYNSFVSLSV 213
YFGEIALLL+RPRAATV A GPLKCVKLDR RFERVLG C++ILKRNI +YNSF+SL+V
Sbjct: 323 YFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 381
Score = 67.3 bits (157), Expect = 6e-11
Identities = 47/152 (30%), Positives = 78/152 (51%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
D SY R ++ + + +S+ + L+ ER + DA+ PV+ ET+++QG
Sbjct: 109 DAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQG 168
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
G++FY++ +G V GE V + FGE+AL+ PRAATV+A LK
Sbjct: 169 NEGDNFYVVDQGEVDVY----VNGEWVT--NISEGGSFGELALIYGTPRAATVKAKTDLK 222
Query: 317 CVKLDRARFERVLGLCADILKRNIAQYNSFVS 222
+DR + R+L + + + KR + Y F+S
Sbjct: 223 LWGIDRDSYRRIL-MGSTLRKRKM--YEEFLS 251
>M65066-1|AAC37564.1| 380|Homo sapiens cAMP-dependent protein
kinase RI-beta regulatory subunit protein.
Length = 380
Score = 300 bits (736), Expect = 4e-81
Identities = 143/179 (79%), Positives = 160/179 (89%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++LIYGTPRAATV+A+T LKLWG+DRDSYRRILMGST+RKR+MY+EFLS+VSILESLEKW
Sbjct: 202 LALIYGTPRAATVKAKTDLKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKW 261
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
ERLTVAD LEPV F D E IV QGEPG+DFYII EGTA VLQ+R E VEVGRLGPSD
Sbjct: 262 ERLTVADRLEPVQFEDGEKIVVQGEPGDDFYIITEGTASVLQRRSPNEEYVEVGRLGPSD 321
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQYNSFVSLSV 213
YFGEIALLL+RPRAATV A GPLKCVKLDR RFERVLG C++ILKRNI +YNSF+SL+V
Sbjct: 322 YFGEIALLLNRPRAATVVARGPLKCVKLDRPRFERVLGPCSEILKRNIQRYNSFISLTV 380
Score = 67.3 bits (157), Expect = 6e-11
Identities = 47/152 (30%), Positives = 78/152 (51%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
D SY R ++ + + +S+ + L+ ER + DA+ PV+ ET+++QG
Sbjct: 108 DAVSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQG 167
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
G++FY++ +G V GE V + FGE+AL+ PRAATV+A LK
Sbjct: 168 NEGDNFYVVDQGEVDVY----VNGEWVT--NISEGGSFGELALIYGTPRAATVKAKTDLK 221
Query: 317 CVKLDRARFERVLGLCADILKRNIAQYNSFVS 222
+DR + R+L + + + KR + Y F+S
Sbjct: 222 LWGIDRDSYRRIL-MGSTLRKRKM--YEEFLS 250
>M33336-1|AAB50921.1| 381|Homo sapiens cAMP-dependent protein
kinase type I-alpha subunit protein.
Length = 381
Score = 299 bits (734), Expect = 7e-81
Identities = 141/179 (78%), Positives = 163/179 (91%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++LIYGTPRAATV+A+T++KLWG+DRDSYRRILMGST+RKR+MY+EFLS+VSILESL+KW
Sbjct: 203 LALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKW 262
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
ERLTVADALEPV F D + IV QGEPG++F+II+EG+A VLQ+R E VEVGRLGPSD
Sbjct: 263 ERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSD 322
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQYNSFVSLSV 213
YFGEIALL++RPRAATV A GPLKCVKLDR RFERVLG C+DILKRNI QYNSFVSLSV
Sbjct: 323 YFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381
Score = 66.5 bits (155), Expect = 1e-10
Identities = 48/152 (31%), Positives = 78/152 (51%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
D SY R ++ + + + + + L+ ER + DA+ VSF ET+++QG
Sbjct: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQG 168
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
+ G++FY+I +G V A VG G FGE+AL+ PRAATV+A +K
Sbjct: 169 DEGDNFYVIDQGETDVYVN---NEWATSVGEGGS---FGELALIYGTPRAATVKAKTNVK 222
Query: 317 CVKLDRARFERVLGLCADILKRNIAQYNSFVS 222
+DR + R+L + + + KR + Y F+S
Sbjct: 223 LWGIDRDSYRRIL-MGSTLRKRKM--YEEFLS 251
>M18468-1|AAB50922.1| 381|Homo sapiens cAMP-dependent protein
kinase regulatory subunit type 1 protein.
Length = 381
Score = 299 bits (734), Expect = 7e-81
Identities = 141/179 (78%), Positives = 163/179 (91%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++LIYGTPRAATV+A+T++KLWG+DRDSYRRILMGST+RKR+MY+EFLS+VSILESL+KW
Sbjct: 203 LALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKW 262
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
ERLTVADALEPV F D + IV QGEPG++F+II+EG+A VLQ+R E VEVGRLGPSD
Sbjct: 263 ERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSD 322
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQYNSFVSLSV 213
YFGEIALL++RPRAATV A GPLKCVKLDR RFERVLG C+DILKRNI QYNSFVSLSV
Sbjct: 323 YFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381
Score = 66.5 bits (155), Expect = 1e-10
Identities = 48/152 (31%), Positives = 78/152 (51%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
D SY R ++ + + + + + L+ ER + DA+ VSF ET+++QG
Sbjct: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQG 168
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
+ G++FY+I +G V A VG G FGE+AL+ PRAATV+A +K
Sbjct: 169 DEGDNFYVIDQGETDVYVN---NEWATSVGEGGS---FGELALIYGTPRAATVKAKTNVK 222
Query: 317 CVKLDRARFERVLGLCADILKRNIAQYNSFVS 222
+DR + R+L + + + KR + Y F+S
Sbjct: 223 LWGIDRDSYRRIL-MGSTLRKRKM--YEEFLS 251
>BC093042-1|AAH93042.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 299 bits (734), Expect = 7e-81
Identities = 141/179 (78%), Positives = 163/179 (91%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++LIYGTPRAATV+A+T++KLWG+DRDSYRRILMGST+RKR+MY+EFLS+VSILESL+KW
Sbjct: 203 LALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKW 262
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
ERLTVADALEPV F D + IV QGEPG++F+II+EG+A VLQ+R E VEVGRLGPSD
Sbjct: 263 ERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSD 322
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQYNSFVSLSV 213
YFGEIALL++RPRAATV A GPLKCVKLDR RFERVLG C+DILKRNI QYNSFVSLSV
Sbjct: 323 YFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381
Score = 66.5 bits (155), Expect = 1e-10
Identities = 48/152 (31%), Positives = 78/152 (51%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
D SY R ++ + + + + + L+ ER + DA+ VSF ET+++QG
Sbjct: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQG 168
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
+ G++FY+I +G V A VG G FGE+AL+ PRAATV+A +K
Sbjct: 169 DEGDNFYVIDQGETDVYVN---NEWATSVGEGGS---FGELALIYGTPRAATVKAKTNVK 222
Query: 317 CVKLDRARFERVLGLCADILKRNIAQYNSFVS 222
+DR + R+L + + + KR + Y F+S
Sbjct: 223 LWGIDRDSYRRIL-MGSTLRKRKM--YEEFLS 251
>BC036285-1|AAH36285.1| 381|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type I, alpha (tissue
specific exti protein.
Length = 381
Score = 299 bits (734), Expect = 7e-81
Identities = 141/179 (78%), Positives = 163/179 (91%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++LIYGTPRAATV+A+T++KLWG+DRDSYRRILMGST+RKR+MY+EFLS+VSILESL+KW
Sbjct: 203 LALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKW 262
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
ERLTVADALEPV F D + IV QGEPG++F+II+EG+A VLQ+R E VEVGRLGPSD
Sbjct: 263 ERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSD 322
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQYNSFVSLSV 213
YFGEIALL++RPRAATV A GPLKCVKLDR RFERVLG C+DILKRNI QYNSFVSLSV
Sbjct: 323 YFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381
Score = 66.5 bits (155), Expect = 1e-10
Identities = 48/152 (31%), Positives = 78/152 (51%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
D SY R ++ + + + + + L+ ER + DA+ VSF ET+++QG
Sbjct: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQG 168
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
+ G++FY+I +G V A VG G FGE+AL+ PRAATV+A +K
Sbjct: 169 DEGDNFYVIDQGETDVYVN---NEWATSVGEGGS---FGELALIYGTPRAATVKAKTNVK 222
Query: 317 CVKLDRARFERVLGLCADILKRNIAQYNSFVS 222
+DR + R+L + + + KR + Y F+S
Sbjct: 223 LWGIDRDSYRRIL-MGSTLRKRKM--YEEFLS 251
>BC075800-1|AAH75800.1| 418|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, beta protein.
Length = 418
Score = 155 bits (377), Expect = 1e-37
Identities = 75/176 (42%), Positives = 112/176 (63%), Gaps = 5/176 (2%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++L+Y TPRAAT+ A + LWGLDR ++RRI++ + +KR+MY+ F+ + L+SLE
Sbjct: 224 LALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFS 283
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGE-----AVEVGR 405
ERL V D + +ND E I+ QG+ + F+I+ G + +R E AVE+ R
Sbjct: 284 ERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIAR 343
Query: 404 LGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQY 237
YFGE+AL+ ++PRAA+ A G +KC+ +D FER+LG C +I+KRNIA Y
Sbjct: 344 CSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 399
Score = 66.5 bits (155), Expect = 1e-10
Identities = 45/149 (30%), Positives = 73/149 (48%)
Frame = -2
Query: 671 DSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEP 492
D+ RI+ T +R E + + ++L+ + V DA+ D E ++ QG+
Sbjct: 128 DAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDD 187
Query: 491 GNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLKCV 312
G++FY+I GT + + G VG FGE+AL+ + PRAAT+ A P
Sbjct: 188 GDNFYVIDRGTFDIYVKCDGVGRC--VGNYDNRGSFGELALMYNTPRAATITATSPGALW 245
Query: 311 KLDRARFERVLGLCADILKRNIAQYNSFV 225
LDR F R++ + + KR + Y SF+
Sbjct: 246 GLDRVTFRRII-VKNNAKKRKM--YESFI 271
>X14968-1|CAA33094.1| 404|Homo sapiens protein ( Human testis mRNA
for the RII-alpha subunit of cAMP dependent protein
kinase. ).
Length = 404
Score = 155 bits (376), Expect = 2e-37
Identities = 74/177 (41%), Positives = 112/177 (63%), Gaps = 6/177 (3%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++L+Y TPRAAT+ A + LWGLDR ++RRI++ + +KR+M++ F+ V +L+SLE
Sbjct: 209 LALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVS 268
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVL------QQRGAGGEAVEVG 408
ER+ + D + + D E I+ QGE + FYII G +L + G + VE+
Sbjct: 269 ERMKIVDVIGEKIYKDGERIITQGEKADSFYIIESGEVSILIRSRTKSNKDGGNQEVEIA 328
Query: 407 RLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQY 237
R YFGE+AL+ ++PRAA+ A G +KC+ +D FER+LG C DI+KRNI+ Y
Sbjct: 329 RCHKGQYFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHY 385
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/133 (27%), Positives = 66/133 (49%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
+ D+ R++ T +R E + + ++L++ + V DA+ E ++ QG
Sbjct: 111 EEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQG 170
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
+ G++FY+I GT +L + + VG+ FGE+AL+ + PRAAT+ A
Sbjct: 171 DDGDNFYVIERGTYDILVTK--DNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGS 228
Query: 317 CVKLDRARFERVL 279
LDR F R++
Sbjct: 229 LWGLDRVTFRRII 241
>M31158-1|AAA60099.1| 418|Homo sapiens cAMP-dependent protein
kinase subunit RII-beta protein.
Length = 418
Score = 154 bits (373), Expect = 4e-37
Identities = 75/176 (42%), Positives = 112/176 (63%), Gaps = 5/176 (2%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++L+Y TPRAAT+ A + LWGLDR ++RRI++ + +KR+MY+ F+ + L+SLE
Sbjct: 224 LALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFS 283
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGE-----AVEVGR 405
ERL V D + +ND E I+ QG+ + F+I+ G + +R E AVE+ R
Sbjct: 284 ERLKVVDVIGTKVYNDGEQIIAQGDSADSFFIVESGEVKITMKRKGKSEVEENGAVEMPR 343
Query: 404 LGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQY 237
YFGE+AL+ ++PRAA+ A G +KC+ +D FER+LG C +I+KRNIA Y
Sbjct: 344 CSRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 399
Score = 66.5 bits (155), Expect = 1e-10
Identities = 45/149 (30%), Positives = 73/149 (48%)
Frame = -2
Query: 671 DSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEP 492
D+ RI+ T +R E + + ++L+ + V DA+ D E ++ QG+
Sbjct: 128 DAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDD 187
Query: 491 GNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLKCV 312
G++FY+I GT + + G VG FGE+AL+ + PRAAT+ A P
Sbjct: 188 GDNFYVIDRGTFDIYVKCDGVGRC--VGNYDNRGSFGELALMYNTPRAATITATSPGALW 245
Query: 311 KLDRARFERVLGLCADILKRNIAQYNSFV 225
LDR F R++ + + KR + Y SF+
Sbjct: 246 GLDRVTFRRII-VKNNAKKRKM--YESFI 271
>BT007225-1|AAP35889.1| 382|Homo sapiens protein kinase,
cAMP-dependent, regulatory, type II, alpha protein.
Length = 382
Score = 132 bits (319), Expect = 1e-30
Identities = 67/171 (39%), Positives = 103/171 (60%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++L+Y TPRAAT+ A + LWGLDR ++RRI++ + +KR+M++ F+ V +L+SLE
Sbjct: 209 LALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVS 268
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
ER+ + D + + D E I+ Q + D G + VE+ R
Sbjct: 269 ERMKIVDVIGEKIYKDGERIITQTKSNKD----------------GGNQEVEIARCHKGQ 312
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQY 237
YFGE+AL+ ++PRAA+ A G +KC+ +D FER+LG C DI+KRNI+ Y
Sbjct: 313 YFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHY 363
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/133 (27%), Positives = 66/133 (49%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
+ D+ R++ T +R E + + ++L++ + V DA+ E ++ QG
Sbjct: 111 EEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQG 170
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
+ G++FY+I GT +L + + VG+ FGE+AL+ + PRAAT+ A
Sbjct: 171 DDGDNFYVIERGTYDILVTK--DNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGS 228
Query: 317 CVKLDRARFERVL 279
LDR F R++
Sbjct: 229 LWGLDRVTFRRII 241
>BC002763-1|AAH02763.1| 382|Homo sapiens PRKAR2A protein protein.
Length = 382
Score = 132 bits (319), Expect = 1e-30
Identities = 67/171 (39%), Positives = 103/171 (60%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++L+Y TPRAAT+ A + LWGLDR ++RRI++ + +KR+M++ F+ V +L+SLE
Sbjct: 209 LALMYNTPRAATIVATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLLKSLEVS 268
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
ER+ + D + + D E I+ Q + D G + VE+ R
Sbjct: 269 ERMKIVDVIGEKIYKDGERIITQTKSNKD----------------GGNQEVEIARCHKGQ 312
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQY 237
YFGE+AL+ ++PRAA+ A G +KC+ +D FER+LG C DI+KRNI+ Y
Sbjct: 313 YFGELALVTNKPRAASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHY 363
Score = 60.9 bits (141), Expect = 5e-09
Identities = 37/133 (27%), Positives = 66/133 (49%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
+ D+ R++ T +R E + + ++L++ + V DA+ E ++ QG
Sbjct: 111 EEDTDPRVIHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFERIVKADEHVIDQG 170
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
+ G++FY+I GT +L + + VG+ FGE+AL+ + PRAAT+ A
Sbjct: 171 DDGDNFYVIERGTYDILVTK--DNQTRSVGQYDNRGSFGELALMYNTPRAATIVATSEGS 228
Query: 317 CVKLDRARFERVL 279
LDR F R++
Sbjct: 229 LWGLDRVTFRRII 241
>BC070478-1|AAH70478.1| 80|Homo sapiens PRKAR1B protein protein.
Length = 80
Score = 110 bits (264), Expect = 6e-24
Identities = 51/62 (82%), Positives = 56/62 (90%)
Frame = -2
Query: 650 MGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYII 471
MGST+RKR+MY+EFLS+VSILESLEKWERLTVADALEPV F D E IV QGEPG+DFYII
Sbjct: 1 MGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEPGDDFYII 60
Query: 470 VE 465
E
Sbjct: 61 TE 62
>Z92868-1|CAB07437.1| 686|Homo sapiens cGMP-dependent protein
kinase type I beta protein.
Length = 686
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 184 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 243
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 244 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 303
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 304 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 346
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/104 (26%), Positives = 56/104 (53%)
Frame = -2
Query: 590 LESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEV 411
+++LE + + D + PV + I+++G+ G+ Y++ +G V + E V++
Sbjct: 119 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTK------EGVKL 172
Query: 410 GRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVL 279
+GP FGE+A+L + R ATV+ +K +DR F+ ++
Sbjct: 173 CTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
>Z92867-1|CAB07436.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 169 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 228
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 229 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 288
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 289 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 331
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/132 (24%), Positives = 66/132 (50%)
Frame = -2
Query: 674 RDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGE 495
R ++R+ R + + E + +++LE + + D + PV + I+++G+
Sbjct: 78 RQAFRKFTKSE--RSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 135
Query: 494 PGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLKC 315
G+ Y++ +G V + E V++ +GP FGE+A+L + R ATV+ +K
Sbjct: 136 VGSLVYVMEDGKVEVTK------EGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKL 189
Query: 314 VKLDRARFERVL 279
+DR F+ ++
Sbjct: 190 WAIDRQCFQTIM 201
>Y07512-1|CAA68810.1| 686|Homo sapiens protein ( Human mRNA for
type I beta cGMP-dependent protein kinase (EC
2.7.1.37). ).
Length = 686
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 184 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 243
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 244 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 303
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 304 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 346
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/104 (26%), Positives = 56/104 (53%)
Frame = -2
Query: 590 LESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEV 411
+++LE + + D + PV + I+++G+ G+ Y++ +G V + E V++
Sbjct: 119 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTK------EGVKL 172
Query: 410 GRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVL 279
+GP FGE+A+L + R ATV+ +K +DR F+ ++
Sbjct: 173 CTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
>EF560730-1|ABQ59040.1| 686|Homo sapiens PRKG1 protein protein.
Length = 686
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 184 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 243
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 244 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 303
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 304 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 346
Score = 50.8 bits (116), Expect = 5e-06
Identities = 27/104 (25%), Positives = 55/104 (52%)
Frame = -2
Query: 590 LESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEV 411
+++LE + + D + PV + I+++G+ G+ Y++ +G V + E ++
Sbjct: 119 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTK------EGAKL 172
Query: 410 GRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVL 279
+GP FGE+A+L + R ATV+ +K +DR F+ ++
Sbjct: 173 CTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
>D45864-1|BAA08297.1| 671|Homo sapiens cGMP-dependent protein
kinase type I alpha protein.
Length = 671
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 169 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 228
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 229 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 288
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 289 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 331
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/132 (24%), Positives = 66/132 (50%)
Frame = -2
Query: 674 RDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGE 495
R ++R+ R + + E + +++LE + + D + PV + I+++G+
Sbjct: 78 RQAFRKFTKSE--RSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 135
Query: 494 PGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLKC 315
G+ Y++ +G V + E V++ +GP FGE+A+L + R ATV+ +K
Sbjct: 136 VGSLVYVMEDGKVEVTK------EGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKL 189
Query: 314 VKLDRARFERVL 279
+DR F+ ++
Sbjct: 190 WAIDRQCFQTIM 201
>BC127090-1|AAI27091.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 184 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 243
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 244 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 303
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 304 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 346
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/104 (26%), Positives = 56/104 (53%)
Frame = -2
Query: 590 LESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEV 411
+++LE + + D + PV + I+++G+ G+ Y++ +G V + E V++
Sbjct: 119 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTK------EGVKL 172
Query: 410 GRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVL 279
+GP FGE+A+L + R ATV+ +K +DR F+ ++
Sbjct: 173 CTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
>AL928686-2|CAI40743.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 184 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 243
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 244 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 303
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 304 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 346
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/104 (26%), Positives = 56/104 (53%)
Frame = -2
Query: 590 LESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEV 411
+++LE + + D + PV + I+++G+ G+ Y++ +G V + E V++
Sbjct: 119 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTK------EGVKL 172
Query: 410 GRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVL 279
+GP FGE+A+L + R ATV+ +K +DR F+ ++
Sbjct: 173 CTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
>AL928686-1|CAI40742.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 157 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 216
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 217 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 276
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 277 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 319
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/132 (24%), Positives = 66/132 (50%)
Frame = -2
Query: 674 RDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGE 495
R ++R+ R + + E + +++LE + + D + PV + I+++G+
Sbjct: 66 RQAFRKFTKSE--RSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 123
Query: 494 PGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLKC 315
G+ Y++ +G V + E V++ +GP FGE+A+L + R ATV+ +K
Sbjct: 124 VGSLVYVMEDGKVEVTK------EGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKL 177
Query: 314 VKLDRARFERVL 279
+DR F+ ++
Sbjct: 178 WAIDRQCFQTIM 189
>AL731537-3|CAI17115.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 184 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 243
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 244 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 303
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 304 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 346
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/104 (26%), Positives = 56/104 (53%)
Frame = -2
Query: 590 LESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEV 411
+++LE + + D + PV + I+++G+ G+ Y++ +G V + E V++
Sbjct: 119 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTK------EGVKL 172
Query: 410 GRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVL 279
+GP FGE+A+L + R ATV+ +K +DR F+ ++
Sbjct: 173 CTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
>AL731537-2|CAI17114.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 157 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 216
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 217 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 276
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 277 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 319
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/132 (24%), Positives = 66/132 (50%)
Frame = -2
Query: 674 RDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGE 495
R ++R+ R + + E + +++LE + + D + PV + I+++G+
Sbjct: 66 RQAFRKFTKSE--RSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 123
Query: 494 PGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLKC 315
G+ Y++ +G V + E V++ +GP FGE+A+L + R ATV+ +K
Sbjct: 124 VGSLVYVMEDGKVEVTK------EGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKL 177
Query: 314 VKLDRARFERVL 279
+DR F+ ++
Sbjct: 178 WAIDRQCFQTIM 189
>AL391378-2|CAI39626.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 184 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 243
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 244 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 303
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 304 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 346
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/104 (26%), Positives = 56/104 (53%)
Frame = -2
Query: 590 LESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEV 411
+++LE + + D + PV + I+++G+ G+ Y++ +G V + E V++
Sbjct: 119 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTK------EGVKL 172
Query: 410 GRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVL 279
+GP FGE+A+L + R ATV+ +K +DR F+ ++
Sbjct: 173 CTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
>AL391378-1|CAI39625.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 157 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 216
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 217 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 276
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 277 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 319
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/132 (24%), Positives = 66/132 (50%)
Frame = -2
Query: 674 RDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGE 495
R ++R+ R + + E + +++LE + + D + PV + I+++G+
Sbjct: 66 RQAFRKFTKSE--RSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 123
Query: 494 PGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLKC 315
G+ Y++ +G V + E V++ +GP FGE+A+L + R ATV+ +K
Sbjct: 124 VGSLVYVMEDGKVEVTK------EGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKL 177
Query: 314 VKLDRARFERVL 279
+DR F+ ++
Sbjct: 178 WAIDRQCFQTIM 189
>AL157399-2|CAI41305.1| 686|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 686
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 184 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 243
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 244 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 303
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 304 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 346
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/104 (26%), Positives = 56/104 (53%)
Frame = -2
Query: 590 LESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEV 411
+++LE + + D + PV + I+++G+ G+ Y++ +G V + E V++
Sbjct: 119 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTK------EGVKL 172
Query: 410 GRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVL 279
+GP FGE+A+L + R ATV+ +K +DR F+ ++
Sbjct: 173 CTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
>AL157399-1|CAI41304.1| 659|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 659
Score = 103 bits (247), Expect = 7e-22
Identities = 55/163 (33%), Positives = 90/163 (55%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 157 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 216
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 217 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 276
Query: 389 YFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADI 261
+FGE AL + R A V A + C+ +DR F+ ++G D+
Sbjct: 277 WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDV 319
Score = 54.0 bits (124), Expect = 6e-07
Identities = 32/132 (24%), Positives = 66/132 (50%)
Frame = -2
Query: 674 RDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGE 495
R ++R+ R + + E + +++LE + + D + PV + I+++G+
Sbjct: 66 RQAFRKFTKSE--RSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGD 123
Query: 494 PGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLKC 315
G+ Y++ +G V + E V++ +GP FGE+A+L + R ATV+ +K
Sbjct: 124 VGSLVYVMEDGKVEVTK------EGVKLCTMGPGKVFGELAILYNCTRTATVKTLVNVKL 177
Query: 314 VKLDRARFERVL 279
+DR F+ ++
Sbjct: 178 WAIDRQCFQTIM 189
>Y16106-1|CAA76073.1| 734|Homo sapiens cGMP-dependant protein
kinase protein.
Length = 734
Score = 96.3 bits (229), Expect = 1e-19
Identities = 49/166 (29%), Positives = 91/166 (54%), Gaps = 1/166 (0%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R A+V+A T++K W LDR+ ++ I+ + + Y FL VS+L++L +
Sbjct: 234 LAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPED 293
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+ + D LE ++ + I+R+GE G+ F+I+ +G V Q + + L +
Sbjct: 294 KLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGE 353
Query: 389 YFGEIALLLDRPRAATVRA-HGPLKCVKLDRARFERVLGLCADILK 255
YFGE AL+ D R+A + A + C+ +DR F + +G ++ K
Sbjct: 354 YFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQK 399
Score = 51.2 bits (117), Expect = 4e-06
Identities = 34/138 (24%), Positives = 67/138 (48%)
Frame = -2
Query: 632 KRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAV 453
++++ + L++ L+ L+ + + + + ++ I++QGEPGN +++ EG
Sbjct: 155 EKKLITDALNKNQFLKRLDPQQIKDMVECMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLE 214
Query: 452 VLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVLGL 273
V Q GE + + + FGE+A+L + R A+V+A +K LDR F+ ++
Sbjct: 215 VFQ-----GEKL-LSSIPMWTTFGELAILYNCTRTASVKAITNVKTWALDREVFQNIMRR 268
Query: 272 CADILKRNIAQYNSFVSL 219
A + VSL
Sbjct: 269 TAQARDEQYRNFLRSVSL 286
>X94612-1|CAA64318.1| 762|Homo sapiens Type II cGMP-dependent
protein kinase protein.
Length = 762
Score = 96.3 bits (229), Expect = 1e-19
Identities = 49/166 (29%), Positives = 91/166 (54%), Gaps = 1/166 (0%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R A+V+A T++K W LDR+ ++ I+ + + Y FL VS+L++L +
Sbjct: 234 LAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPED 293
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+ + D LE ++ + I+R+GE G+ F+I+ +G V Q + + L +
Sbjct: 294 KLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGE 353
Query: 389 YFGEIALLLDRPRAATVRA-HGPLKCVKLDRARFERVLGLCADILK 255
YFGE AL+ D R+A + A + C+ +DR F + +G ++ K
Sbjct: 354 YFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQK 399
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/170 (22%), Positives = 80/170 (47%), Gaps = 3/170 (1%)
Frame = -2
Query: 719 ATVRARTSLKLWGLDRD---SYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVAD 549
A V A + + + L++ S+ + + ++++ + L++ L+ L+ + + +
Sbjct: 123 AGVSAEPTTRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVE 182
Query: 548 ALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIAL 369
+ ++ I++QGEPGN +++ EG V Q GE + + + FGE+A+
Sbjct: 183 CMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQ-----GEKL-LSSIPMWTTFGELAI 236
Query: 368 LLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQYNSFVSL 219
L + R A+V+A +K LDR F+ ++ A + VSL
Sbjct: 237 LYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSL 286
>D70899-1|BAA18934.1| 762|Homo sapiens cGMP-dependent protein
kinase II protein.
Length = 762
Score = 96.3 bits (229), Expect = 1e-19
Identities = 49/166 (29%), Positives = 91/166 (54%), Gaps = 1/166 (0%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R A+V+A T++K W LDR+ ++ I+ + + Y FL VS+L++L +
Sbjct: 234 LAILYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSLLKNLPED 293
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+ + D LE ++ + I+R+GE G+ F+I+ +G V Q + + L +
Sbjct: 294 KLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHDQPQLIKTLQKGE 353
Query: 389 YFGEIALLLDRPRAATVRA-HGPLKCVKLDRARFERVLGLCADILK 255
YFGE AL+ D R+A + A + C+ +DR F + +G ++ K
Sbjct: 354 YFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVGTFEELQK 399
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/170 (22%), Positives = 80/170 (47%), Gaps = 3/170 (1%)
Frame = -2
Query: 719 ATVRARTSLKLWGLDRD---SYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVAD 549
A V A + + + L++ S+ + + ++++ + L++ L+ L+ + + +
Sbjct: 123 AGVSAEPTTRTYDLNKPPEFSFEKARVRKDSSEKKLITDALNKNQFLKRLDPQQIKDMVE 182
Query: 548 ALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIAL 369
+ ++ I++QGEPGN +++ EG V Q GE + + + FGE+A+
Sbjct: 183 CMYGRNYQQGSYIIKQGEPGNHIFVLAEGRLEVFQ-----GEKL-LSSIPMWTTFGELAI 236
Query: 368 LLDRPRAATVRAHGPLKCVKLDRARFERVLGLCADILKRNIAQYNSFVSL 219
L + R A+V+A +K LDR F+ ++ A + VSL
Sbjct: 237 LYNCTRTASVKAITNVKTWALDREVFQNIMRRTAQARDEQYRNFLRSVSL 286
>BC062688-1|AAH62688.1| 312|Homo sapiens PRKG1 protein protein.
Length = 312
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/127 (35%), Positives = 72/127 (56%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 184 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 243
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 244 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 303
Query: 389 YFGEIAL 369
+FGE AL
Sbjct: 304 WFGEKAL 310
Score = 52.4 bits (120), Expect = 2e-06
Identities = 28/104 (26%), Positives = 56/104 (53%)
Frame = -2
Query: 590 LESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEV 411
+++LE + + D + PV + I+++G+ G+ Y++ +G V + E V++
Sbjct: 119 MKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMEDGKVEVTK------EGVKL 172
Query: 410 GRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARFERVL 279
+GP FGE+A+L + R ATV+ +K +DR F+ ++
Sbjct: 173 CTMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 216
>AL391378-3|CAI39627.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/127 (35%), Positives = 72/127 (56%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 42 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 101
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 102 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 161
Query: 389 YFGEIAL 369
+FGE AL
Sbjct: 162 WFGEKAL 168
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/78 (29%), Positives = 44/78 (56%)
Frame = -2
Query: 512 IVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRA 333
I+++G+ G+ Y++ +G V + E V++ +GP FGE+A+L + R ATV+
Sbjct: 3 IIKEGDVGSLVYVMEDGKVEVTK------EGVKLCTMGPGKVFGELAILYNCTRTATVKT 56
Query: 332 HGPLKCVKLDRARFERVL 279
+K +DR F+ ++
Sbjct: 57 LVNVKLWAIDRQCFQTIM 74
>AL157399-3|CAI41306.1| 181|Homo sapiens protein kinase,
cGMP-dependent, type I protein.
Length = 181
Score = 88.6 bits (210), Expect = 2e-17
Identities = 45/127 (35%), Positives = 72/127 (56%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++++Y R ATV+ ++KLW +DR ++ I+M + + K Y EFL V +SL +
Sbjct: 42 LAILYNCTRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEE 101
Query: 569 ERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSD 390
+AD LE + + E I+RQG G+ F+II +GT V ++ + V + LG D
Sbjct: 102 ILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVNVTREDSPSEDPVFLRTLGKGD 161
Query: 389 YFGEIAL 369
+FGE AL
Sbjct: 162 WFGEKAL 168
Score = 42.3 bits (95), Expect = 0.002
Identities = 23/78 (29%), Positives = 44/78 (56%)
Frame = -2
Query: 512 IVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRA 333
I+++G+ G+ Y++ +G V + E V++ +GP FGE+A+L + R ATV+
Sbjct: 3 IIKEGDVGSLVYVMEDGKVEVTK------EGVKLCTMGPGKVFGELAILYNCTRTATVKT 56
Query: 332 HGPLKCVKLDRARFERVL 279
+K +DR F+ ++
Sbjct: 57 LVNVKLWAIDRQCFQTIM 74
>AC006387-1|AAS07389.1| 306|Homo sapiens unknown protein.
Length = 306
Score = 81.4 bits (192), Expect = 3e-15
Identities = 37/83 (44%), Positives = 56/83 (67%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKW 570
++L+Y TPRAAT+ A + LWGLDR ++RRI++ + +KR+MY+ F+ + L+SLE
Sbjct: 224 LALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEFS 283
Query: 569 ERLTVADALEPVSFNDSETIVRQ 501
ERL V D + +ND E I+ Q
Sbjct: 284 ERLKVVDVIGTKVYNDGEQIIAQ 306
Score = 66.5 bits (155), Expect = 1e-10
Identities = 45/149 (30%), Positives = 73/149 (48%)
Frame = -2
Query: 671 DSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEP 492
D+ RI+ T +R E + + ++L+ + V DA+ D E ++ QG+
Sbjct: 128 DAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKDGEHVIDQGDD 187
Query: 491 GNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLKCV 312
G++FY+I GT + + G VG FGE+AL+ + PRAAT+ A P
Sbjct: 188 GDNFYVIDRGTFDIYVKCDGVGRC--VGNYDNRGSFGELALMYNTPRAATITATSPGALW 245
Query: 311 KLDRARFERVLGLCADILKRNIAQYNSFV 225
LDR F R++ + + KR + Y SF+
Sbjct: 246 GLDRVTFRRII-VKNNAKKRKM--YESFI 271
>AC004492-1|AAC08318.1| 112|Homo sapiens CAMP-DEPENDENT PROTEIN
KINASE TYPE II-BETA REGULATORY CHAIN protein.
Length = 112
Score = 78.6 bits (185), Expect = 2e-14
Identities = 38/93 (40%), Positives = 56/93 (60%), Gaps = 5/93 (5%)
Frame = -2
Query: 500 GEPGNDFYIIVEGTAVVLQQRGAGGE-----AVEVGRLGPSDYFGEIALLLDRPRAATVR 336
G+ + F+I+ G + +R E AVE+ R YFGE+AL+ ++PRAA+
Sbjct: 1 GDSADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCSRGQYFGELALVTNKPRAASAH 60
Query: 335 AHGPLKCVKLDRARFERVLGLCADILKRNIAQY 237
A G +KC+ +D FER+LG C +I+KRNIA Y
Sbjct: 61 AIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 93
>L03357-1|AAA60266.1| 593|Homo sapiens RET tyrosine kinase/cAMP
protein kinase A subunit RI protein.
Length = 593
Score = 65.3 bits (152), Expect = 2e-10
Identities = 27/34 (79%), Positives = 34/34 (100%)
Frame = -2
Query: 749 ISLIYGTPRAATVRARTSLKLWGLDRDSYRRILM 648
++LIYGTPRAATV+A+T++KLWG+DRDSYRRILM
Sbjct: 203 LALIYGTPRAATVKAKTNVKLWGIDRDSYRRILM 236
Score = 64.9 bits (151), Expect = 3e-10
Identities = 43/133 (32%), Positives = 68/133 (51%)
Frame = -2
Query: 677 DRDSYRRILMGSTIRKRRMYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIVRQG 498
D SY R ++ + + + + + L+ ER + DA+ VSF ET+++QG
Sbjct: 109 DAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQG 168
Query: 497 EPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGPLK 318
+ G++FY+I +G V A VG G FGE+AL+ PRAATV+A +K
Sbjct: 169 DEGDNFYVIDQGETDVYVN---NEWATSVGEGGS---FGELALIYGTPRAATVKAKTNVK 222
Query: 317 CVKLDRARFERVL 279
+DR + R+L
Sbjct: 223 LWGIDRDSYRRIL 235
>BC040183-1|AAH40183.1| 867|Homo sapiens RAPGEF4 protein protein.
Length = 867
Score = 45.6 bits (103), Expect = 2e-04
Identities = 44/149 (29%), Positives = 72/149 (48%), Gaps = 8/149 (5%)
Frame = -2
Query: 701 TSLKLWGLDRDSYRRILMGSTIRKRRMYD-----EFLSRVSILESLEKWERLTVADALEP 537
T L L + RD++ R+++ +R + D E L + L L + +A L
Sbjct: 171 TMLLLSQMGRDAHMRMILRKPPGQRTVDDLEIIYEELLHIKALSHLSTTVKRELAGVLIF 230
Query: 536 VSFNDSETIV-RQGEPGNDFYIIVEGTA-VVLQQRGAGGEAVEVGRLGPSDYFGEIALLL 363
S T++ QGE G +YII++G+ VV+ +G V L D FG++AL+
Sbjct: 231 ESHAKGGTVLFNQGEEGTSWYIILKGSVNVVIYGKGV------VCTLHEGDDFGKLALVN 284
Query: 362 DRPRAAT-VRAHGPLKCVKLDRARFERVL 279
D PRAA+ V +++D+ F R+L
Sbjct: 285 DAPRAASIVLREDNCHFLRVDKEDFNRIL 313
>BC040277-1|AAH40277.1| 474|Homo sapiens CNGA4 protein protein.
Length = 474
Score = 44.8 bits (101), Expect = 3e-04
Identities = 28/81 (34%), Positives = 43/81 (53%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
LSRV I ++ E + L+P +++ E + R+G+ G + YII EG V+ G
Sbjct: 361 LSRVQIFQNCEASLLEELVLKLQPQTYSPGEYVCRKGDIGQEMYIIREGQLAVVADDGIT 420
Query: 428 GEAVEVGRLGPSDYFGEIALL 366
AV LG YFGEI+++
Sbjct: 421 QYAV----LGAGLYFGEISII 437
>U78516-1|AAD03422.1| 1011|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor II protein.
Length = 1011
Score = 42.7 bits (96), Expect = 0.001
Identities = 37/118 (31%), Positives = 59/118 (50%), Gaps = 3/118 (2%)
Frame = -2
Query: 623 MYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIV-RQGEPGNDFYIIVEGTA-VV 450
+Y+E L + L L + +A L S T++ QGE G +YII++G+ VV
Sbjct: 347 IYEELL-HIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVV 405
Query: 449 LQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAAT-VRAHGPLKCVKLDRARFERVL 279
+ +G V L D FG++AL+ D PRAA+ V +++D+ F R+L
Sbjct: 406 IYGKGV------VCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRIL 457
>BC024004-1|AAH24004.1| 1011|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 4 protein.
Length = 1011
Score = 42.7 bits (96), Expect = 0.001
Identities = 37/118 (31%), Positives = 59/118 (50%), Gaps = 3/118 (2%)
Frame = -2
Query: 623 MYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIV-RQGEPGNDFYIIVEGTA-VV 450
+Y+E L + L L + +A L S T++ QGE G +YII++G+ VV
Sbjct: 347 IYEELL-HIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVV 405
Query: 449 LQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAAT-VRAHGPLKCVKLDRARFERVL 279
+ +G V L D FG++AL+ D PRAA+ V +++D+ F R+L
Sbjct: 406 IYGKGV------VCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRIL 457
>AB027471-1|BAB72179.1| 1011|Homo sapiens cAMP-GEFII protein.
Length = 1011
Score = 42.7 bits (96), Expect = 0.001
Identities = 37/118 (31%), Positives = 59/118 (50%), Gaps = 3/118 (2%)
Frame = -2
Query: 623 MYDEFLSRVSILESLEKWERLTVADALEPVSFNDSETIV-RQGEPGNDFYIIVEGTA-VV 450
+Y+E L + L L + +A L S T++ QGE G +YII++G+ VV
Sbjct: 347 IYEELL-HIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVV 405
Query: 449 LQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAAT-VRAHGPLKCVKLDRARFERVL 279
+ +G V L D FG++AL+ D PRAA+ V +++D+ F R+L
Sbjct: 406 IYGKGV------VCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRIL 457
>BC051768-1|AAH51768.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/81 (30%), Positives = 40/81 (49%)
Frame = -2
Query: 548 ALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIAL 369
A++ + + RQG+ + YI++ G + QRG+G + + VG G D G +
Sbjct: 596 AIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKEL-VGEYGRGDLIGVVEA 654
Query: 368 LLDRPRAATVRAHGPLKCVKL 306
L +PRA TV A + KL
Sbjct: 655 LTRQPRATTVHAVRDTELAKL 675
>BC050553-1|AAH50553.1| 1327|Homo sapiens patatin-like phospholipase
domain containing 6 protein.
Length = 1327
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/81 (30%), Positives = 40/81 (49%)
Frame = -2
Query: 548 ALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIAL 369
A++ + + RQG+ + YI++ G + QRG+G + + VG G D G +
Sbjct: 596 AIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKEL-VGEYGRGDLIGVVEA 654
Query: 368 LLDRPRAATVRAHGPLKCVKL 306
L +PRA TV A + KL
Sbjct: 655 LTRQPRATTVHAVRDTELAKL 675
>AJ004832-1|CAA06164.1| 1327|Homo sapiens neuropathy target esterase
protein.
Length = 1327
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/81 (30%), Positives = 40/81 (49%)
Frame = -2
Query: 548 ALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIAL 369
A++ + + RQG+ + YI++ G + QRG+G + + VG G D G +
Sbjct: 596 AIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKEL-VGEYGRGDLIGVVEA 654
Query: 368 LLDRPRAATVRAHGPLKCVKL 306
L +PRA TV A + KL
Sbjct: 655 LTRQPRATTVHAVRDTELAKL 675
>U58837-1|AAB63387.1| 1251|Homo sapiens cGMP-gated cation channel beta
subunit protein.
Length = 1251
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
+S+V++ + ++ + L V + ++ + ++GE G + YII G VL G
Sbjct: 957 VSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVL--GGPD 1014
Query: 428 GEAVEVGRLGPSDYFGEIALLL---DRPRAATVRAHGPLKCVKLDRARFERVL 279
G++V V L FGEI+LL R A V AHG LD+ +L
Sbjct: 1015 GKSVLV-TLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEIL 1066
>L15297-1|AAA65619.1| 623|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 623
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
+S+V++ + ++ + L V + ++ + ++GE G + YII G VL G
Sbjct: 329 VSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVL--GGPD 386
Query: 428 GEAVEVGRLGPSDYFGEIALLL---DRPRAATVRAHGPLKCVKLDRARFERVL 279
G++V V L FGEI+LL R A V AHG LD+ +L
Sbjct: 387 GKSVLV-TLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEIL 438
>L15296-1|AAA65620.1| 909|Homo sapiens cyclic nucleotide-gated
cation channel protein.
Length = 909
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
+S+V++ + ++ + L V + ++ + ++GE G + YII G VL G
Sbjct: 615 VSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVL--GGPD 672
Query: 428 GEAVEVGRLGPSDYFGEIALLL---DRPRAATVRAHGPLKCVKLDRARFERVL 279
G++V V L FGEI+LL R A V AHG LD+ +L
Sbjct: 673 GKSVLV-TLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEIL 724
>AF042498-1|AAC04830.1| 1245|Homo sapiens rod photoreceptor
CNG-channel beta subunit protein.
Length = 1245
Score = 41.5 bits (93), Expect = 0.003
Identities = 33/113 (29%), Positives = 53/113 (46%), Gaps = 3/113 (2%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
+S+V++ + ++ + L V + ++ + ++GE G + YII G VL G
Sbjct: 951 VSKVALFQGCDRQMIFDMLKRLRSVVYLPNDYVCKKGEIGREMYIIQAGQVQVL--GGPD 1008
Query: 428 GEAVEVGRLGPSDYFGEIALLL---DRPRAATVRAHGPLKCVKLDRARFERVL 279
G++V V L FGEI+LL R A V AHG LD+ +L
Sbjct: 1009 GKSVLV-TLKAGSVFGEISLLAVGGGNRRTANVVAHGFTNLFILDKKDLNEIL 1060
>AB209681-1|BAD92918.1| 643|Homo sapiens RAP
guanine-nucleotide-exchange factor 4 variant protein.
Length = 643
Score = 41.1 bits (92), Expect = 0.004
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 2/80 (2%)
Frame = -2
Query: 512 IVRQGEPGNDFYIIVEGTA-VVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAAT-V 339
+ QGE G +YII++G+ VV+ +G V L D FG++AL+ D PRAA+ V
Sbjct: 16 VFNQGEEGTSWYIILKGSVNVVIYGKGV------VCTLHEGDDFGKLALVNDAPRAASIV 69
Query: 338 RAHGPLKCVKLDRARFERVL 279
+++D+ F R+L
Sbjct: 70 LREDNCHFLRVDKEDFNRIL 89
>BC028024-1|AAH28024.2| 450|Homo sapiens HCN3 protein protein.
Length = 450
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/84 (36%), Positives = 36/84 (42%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + +VR+G G Y I G VL RGA RL YFGEI LL R
Sbjct: 125 FQPGDLVVREGSVGRKMYFIQHGLLSVLA-RGARDT-----RLTDGSYFGEICLLTRGRR 178
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 179 TASVRADTYCRLYSLSVDHFNAVL 202
>BC000066-1|AAH00066.1| 571|Homo sapiens Unknown (protein for
IMAGE:3507934) protein.
Length = 571
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/84 (36%), Positives = 36/84 (42%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + +VR+G G Y I G VL RGA RL YFGEI LL R
Sbjct: 246 FQPGDLVVREGSVGRKMYFIQHGLLSVLA-RGARDT-----RLTDGSYFGEICLLTRGRR 299
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 300 TASVRADTYCRLYSLSVDHFNAVL 323
>AL713999-31|CAI95100.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel 3
protein.
Length = 774
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/84 (36%), Positives = 36/84 (42%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + +VR+G G Y I G VL RGA RL YFGEI LL R
Sbjct: 449 FQPGDLVVREGSVGRKMYFIQHGLLSVLA-RGARDT-----RLTDGSYFGEICLLTRGRR 502
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 503 TASVRADTYCRLYSLSVDHFNAVL 526
>AF488550-1|AAO49470.1| 774|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 774
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/84 (36%), Positives = 36/84 (42%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + +VR+G G Y I G VL RGA RL YFGEI LL R
Sbjct: 449 FQPGDLVVREGSVGRKMYFIQHGLLSVLA-RGARDT-----RLTDGSYFGEICLLTRGRR 502
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 503 TASVRADTYCRLYSLSVDHFNAVL 526
>AB040968-1|BAA96059.2| 711|Homo sapiens KIAA1535 protein protein.
Length = 711
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/84 (36%), Positives = 36/84 (42%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + +VR+G G Y I G VL RGA RL YFGEI LL R
Sbjct: 386 FQPGDLVVREGSVGRKMYFIQHGLLSVLA-RGARDT-----RLTDGSYFGEICLLTRGRR 439
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 440 TASVRADTYCRLYSLSVDHFNAVL 463
>BC038229-1|AAH38229.1| 1332|Homo sapiens PNPLA6 protein protein.
Length = 1332
Score = 40.3 bits (90), Expect = 0.007
Identities = 24/81 (29%), Positives = 39/81 (48%)
Frame = -2
Query: 548 ALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIAL 369
A++ + + RQG+ + YI++ G + QRG+G + + VG G D G +
Sbjct: 602 AIDWTAVEAGRALYRQGDRSDCTYIVLNGRLRSVIQRGSGKKEL-VGEYGRGDLIGVVEA 660
Query: 368 LLDRPRAATVRAHGPLKCVKL 306
L +PRA TV + KL
Sbjct: 661 LTRQPRATTVHTVRDTELAKL 681
>AF272900-1|AAF86274.1| 809|Homo sapiens cone photoreceptor cyclic
nucleotide-gated channel beta subunit protein.
Length = 809
Score = 39.9 bits (89), Expect = 0.010
Identities = 33/113 (29%), Positives = 51/113 (45%), Gaps = 3/113 (2%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
+S+V + + + + L+ V + + + ++GE G + YII G VL G
Sbjct: 519 ISKVDLFKGCDTQMIYDMLLRLKSVLYLPGDFVCKKGEIGKEMYIIKHGEVQVL--GGPD 576
Query: 428 GEAVEVGRLGPSDYFGEIALLL---DRPRAATVRAHGPLKCVKLDRARFERVL 279
G V V L FGEI+LL R A V AHG + LD+ + +L
Sbjct: 577 GTKVLV-TLKAGSVFGEISLLAAGGGNRRTANVVAHGFANLLTLDKKTLQEIL 628
>AJ133727-1|CAB42630.1| 889|Homo sapiens
hyperpolarization-activated cyclic nucleotide-gated
channel hHCN2 protein.
Length = 889
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/84 (33%), Positives = 37/84 (44%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + I+R+G G Y I G VL + G + + +L YFGEI LL R
Sbjct: 565 FQPGDYIIREGTIGKKMYFIQHGVVSVLTK---GNKEM---KLSDGSYFGEICLLTRGRR 618
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 619 TASVRADTYCRLYSLSVDNFNEVL 642
>AJ012582-1|CAB42602.1| 889|Homo sapiens
hyperpolarization-activated cation channel HCN2 protein.
Length = 889
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/84 (33%), Positives = 37/84 (44%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + I+R+G G Y I G VL + G + + +L YFGEI LL R
Sbjct: 565 FQPGDYIIREGTIGKKMYFIQHGVVSVLTK---GNKEM---KLSDGSYFGEICLLTRGRR 618
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 619 TASVRADTYCRLYSLSVDNFNEVL 642
>AF065164-1|AAC28444.2| 889|Homo sapiens
hyperpolarization-activated, cyclic nucleotide-gated
channel 2 protein.
Length = 889
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/84 (33%), Positives = 37/84 (44%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + I+R+G G Y I G VL + G + + +L YFGEI LL R
Sbjct: 565 FQPGDYIIREGTIGKKMYFIQHGVVSVLTK---GNKEM---KLSDGSYFGEICLLTRGRR 618
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 619 TASVRADTYCRLYSLSVDNFNEVL 642
>AF064877-1|AAC39760.1| 597|Homo sapiens ion channel BCNG-2
protein.
Length = 597
Score = 39.1 bits (87), Expect = 0.017
Identities = 28/84 (33%), Positives = 37/84 (44%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + I+R+G G Y I G VL + G + + +L YFGEI LL R
Sbjct: 419 FQPGDYIIREGTIGKKMYFIQHGVVSVLTK---GNKEM---KLSDGSYFGEICLLTRGRR 472
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 473 TASVRADTYCRLYSLSVDNFNEVL 496
>AJ238850-1|CAB52754.1| 1203|Homo sapiens
hyperpolarization-activated channel type 4 protein.
Length = 1203
Score = 38.7 bits (86), Expect = 0.023
Identities = 28/84 (33%), Positives = 36/84 (42%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + I+R+G G Y I G VL + G + +L YFGEI LL R
Sbjct: 616 FQPGDYIIREGTIGKKMYFIQHGVVSVLTK---GNKET---KLADGSYFGEICLLTRGRR 669
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 670 TASVRADTYCRLYSLSVDNFNEVL 693
>AJ132429-1|CAB42604.1| 1203|Homo sapiens
hyperpolarization-activated cyclic nucleotide gated
cation channel hHCN4 protein.
Length = 1203
Score = 38.7 bits (86), Expect = 0.023
Identities = 28/84 (33%), Positives = 36/84 (42%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + I+R+G G Y I G VL + G + +L YFGEI LL R
Sbjct: 616 FQPGDYIIREGTIGKKMYFIQHGVVSVLTK---GNKET---KLADGSYFGEICLLTRGRR 669
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 670 TASVRADTYCRLYSLSVDNFNEVL 693
>AF064876-1|AAC39759.1| 749|Homo sapiens ion channel BCNG-1
protein.
Length = 749
Score = 38.7 bits (86), Expect = 0.023
Identities = 28/84 (33%), Positives = 38/84 (45%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + I+R+G G Y I G A V+ + + E+ +L YFGEI LL R
Sbjct: 375 FQPGDYIIREGAVGKKMYFIQHGVAGVITK-----SSKEM-KLTDGSYFGEICLLTKGRR 428
Query: 350 AATVRAHGPLKCVKLDRARFERVL 279
A+VRA + L F VL
Sbjct: 429 TASVRADTYCRLYSLSVDNFNEVL 452
>U78169-1|AAD02890.1| 556|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 556
Score = 37.9 bits (84), Expect = 0.039
Identities = 26/77 (33%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = -2
Query: 503 QGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGP 324
QG+ G +YII +G+ V+ G+ + V L D FG++AL+ D PRAAT+
Sbjct: 234 QGDKGTSWYIIWKGSVNVVTH----GKGL-VTTLHEGDDFGQLALVNDAPRAATIILR-E 287
Query: 323 LKC--VKLDRARFERVL 279
C +++D+ F R++
Sbjct: 288 YNCHFLRVDKQDFNRII 304
>U78168-1|AAD12740.1| 881|Homo sapiens cAMP-regulated guanine
nucleotide exchange factor I protein.
Length = 881
Score = 37.9 bits (84), Expect = 0.039
Identities = 26/77 (33%), Positives = 43/77 (55%), Gaps = 2/77 (2%)
Frame = -2
Query: 503 QGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAATVRAHGP 324
QG+ G +YII +G+ V+ G+ + V L D FG++AL+ D PRAAT+
Sbjct: 234 QGDKGTSWYIIWKGSVNVVTH----GKGL-VTTLHEGDDFGQLALVNDAPRAATIILR-E 287
Query: 323 LKC--VKLDRARFERVL 279
C +++D+ F R++
Sbjct: 288 YNCHFLRVDKQDFNRII 304
>BC092404-1|AAH92404.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = -2
Query: 503 QGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAAT-VRAHG 327
QG+ G +YII +G+ V+ G+ + V L D FG++AL+ D PRAAT +
Sbjct: 234 QGDKGTSWYIIWKGSVNVVTH----GKGL-VTTLHEGDDFGQLALVNDAPRAATIILRED 288
Query: 326 PLKCVKLDRARFERVL 279
+++D+ F R++
Sbjct: 289 NCHFLRVDKQDFNRII 304
>BC068477-1|AAH68477.1| 343|Homo sapiens RAPGEF3 protein protein.
Length = 343
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = -2
Query: 503 QGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAAT-VRAHG 327
QG+ G +YII +G+ V+ G+ + V L D FG++AL+ D PRAAT +
Sbjct: 234 QGDKGTSWYIIWKGSVNVVTH----GKGL-VTTLHEGDDFGQLALVNDAPRAATIILRED 288
Query: 326 PLKCVKLDRARFERVL 279
+++D+ F R++
Sbjct: 289 NCHFLRVDKQDFNRII 304
>BC040534-1|AAH40534.1| 321|Homo sapiens RAPGEF3 protein protein.
Length = 321
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = -2
Query: 503 QGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAAT-VRAHG 327
QG+ G +YII +G+ V+ G+ + V L D FG++AL+ D PRAAT +
Sbjct: 234 QGDKGTSWYIIWKGSVNVVTH----GKGL-VTTLHEGDDFGQLALVNDAPRAATIILRED 288
Query: 326 PLKCVKLDRARFERVL 279
+++D+ F R++
Sbjct: 289 NCHFLRVDKQDFNRII 304
>BC017728-1|AAH17728.1| 881|Homo sapiens Rap guanine nucleotide
exchange factor (GEF) 3 protein.
Length = 881
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = -2
Query: 503 QGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAAT-VRAHG 327
QG+ G +YII +G+ V+ G+ + V L D FG++AL+ D PRAAT +
Sbjct: 234 QGDKGTSWYIIWKGSVNVVTH----GKGL-VTTLHEGDDFGQLALVNDAPRAATIILRED 288
Query: 326 PLKCVKLDRARFERVL 279
+++D+ F R++
Sbjct: 289 NCHFLRVDKQDFNRII 304
>AF103905-1|AAC83381.1| 881|Homo sapiens Rap1 guanine-nucleotide
exchange factor protein.
Length = 881
Score = 37.9 bits (84), Expect = 0.039
Identities = 25/76 (32%), Positives = 42/76 (55%), Gaps = 1/76 (1%)
Frame = -2
Query: 503 QGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPRAAT-VRAHG 327
QG+ G +YII +G+ V+ G+ + V L D FG++AL+ D PRAAT +
Sbjct: 234 QGDKGTSWYIIWKGSVNVVTH----GKGL-VTTLHEGDDFGQLALVNDAPRAATIILRED 288
Query: 326 PLKCVKLDRARFERVL 279
+++D+ F R++
Sbjct: 289 NCHFLRVDKQDFNRII 304
>S76062-1|AAD14206.1| 261|Homo sapiens CNG1 protein.
Length = 261
Score = 37.5 bits (83), Expect = 0.052
Identities = 24/81 (29%), Positives = 38/81 (46%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
L +V I E + + L+P ++ + I ++G+ G + YII EG V+ G
Sbjct: 158 LKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVT 217
Query: 428 GEAVEVGRLGPSDYFGEIALL 366
V L YFGEI++L
Sbjct: 218 QFVV----LSDGSYFGEISIL 234
>S42457-1|AAB22778.1| 686|Homo sapiens rod photoreceptor cGMP-gated
channel protein.
Length = 686
Score = 37.5 bits (83), Expect = 0.052
Identities = 24/81 (29%), Positives = 38/81 (46%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
L +V I E + + L+P ++ + I ++G+ G + YII EG V+ G
Sbjct: 470 LKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVT 529
Query: 428 GEAVEVGRLGPSDYFGEIALL 366
V L YFGEI++L
Sbjct: 530 QFVV----LSDGSYFGEISIL 546
>AF488549-1|AAO49469.1| 890|Homo sapiens hyperpolarization
activated cyclic nucleotide-gated potassium channel
protein.
Length = 890
Score = 37.5 bits (83), Expect = 0.052
Identities = 28/83 (33%), Positives = 37/83 (44%)
Frame = -2
Query: 530 FNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIALLLDRPR 351
F + IVR+G G Y I G A V+ + + E+ +L YFGEI LL R
Sbjct: 496 FQPGDYIVREGAVGKKMYFIQHGVAGVITK-----SSKEM-KLTDGSYFGEICLLTKGRR 549
Query: 350 AATVRAHGPLKCVKLDRARFERV 282
A+VRA + L F V
Sbjct: 550 TASVRADTYCRLYSLSVDNFNEV 572
>AC107068-3|AAY40919.1| 690|Homo sapiens unknown protein.
Length = 690
Score = 37.5 bits (83), Expect = 0.052
Identities = 24/81 (29%), Positives = 38/81 (46%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
L +V I E + + L+P ++ + I ++G+ G + YII EG V+ G
Sbjct: 474 LKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVT 533
Query: 428 GEAVEVGRLGPSDYFGEIALL 366
V L YFGEI++L
Sbjct: 534 QFVV----LSDGSYFGEISIL 550
>S76067-1|AAD14207.1| 261|Homo sapiens CNG2 protein.
Length = 261
Score = 36.7 bits (81), Expect = 0.091
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
L +V I E + + L P F+ + I R+G+ G + YII EG V+ G
Sbjct: 158 LKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDG-- 215
Query: 428 GEAVEVGRLGPSDYFGEIALL 366
+ L FGEI++L
Sbjct: 216 --VTQYALLSAGSCFGEISIL 234
>BC126304-1|AAI26305.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 36.7 bits (81), Expect = 0.091
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
L +V I E + + L P F+ + I R+G+ G + YII EG V+ G
Sbjct: 449 LKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDG-- 506
Query: 428 GEAVEVGRLGPSDYFGEIALL 366
+ L FGEI++L
Sbjct: 507 --VTQYALLSAGSCFGEISIL 525
>BC126302-1|AAI26303.1| 664|Homo sapiens cyclic nucleotide gated
channel alpha 2 protein.
Length = 664
Score = 36.7 bits (81), Expect = 0.091
Identities = 24/81 (29%), Positives = 36/81 (44%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
L +V I E + + L P F+ + I R+G+ G + YII EG V+ G
Sbjct: 449 LKKVRIFHDCEAGLLVELVLKLRPQVFSPGDYICRKGDIGKEMYIIKEGKLAVVADDG-- 506
Query: 428 GEAVEVGRLGPSDYFGEIALL 366
+ L FGEI++L
Sbjct: 507 --VTQYALLSAGSCFGEISIL 525
>BC114945-1|AAI14946.1| 423|Homo sapiens C20orf152 protein protein.
Length = 423
Score = 34.3 bits (75), Expect = 0.48
Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 8/120 (6%)
Frame = -2
Query: 626 RMYDEFLSRVSILESLEKWE------RLTVADALEPVSFNDSETIVRQGEPGNDFYIIVE 465
R DE + +IL+ L+ + +L +A + F I+++G+ GN FY I
Sbjct: 99 RTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYL 158
Query: 464 GTAVVLQQRGAGGEAVE--VGRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARF 291
GT + + ++ L FGE+ +L R +T+ + + +DR F
Sbjct: 159 GTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF 218
>AL359828-2|CAI23442.1| 572|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 572
Score = 34.3 bits (75), Expect = 0.48
Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 8/120 (6%)
Frame = -2
Query: 626 RMYDEFLSRVSILESLEKWE------RLTVADALEPVSFNDSETIVRQGEPGNDFYIIVE 465
R DE + +IL+ L+ + +L +A + F I+++G+ GN FY I
Sbjct: 99 RTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYL 158
Query: 464 GTAVVLQQRGAGGEAVE--VGRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARF 291
GT + + ++ L FGE+ +L R +T+ + + +DR F
Sbjct: 159 GTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF 218
>AL359828-1|CAI23441.1| 576|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 576
Score = 34.3 bits (75), Expect = 0.48
Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 8/120 (6%)
Frame = -2
Query: 626 RMYDEFLSRVSILESLEKWE------RLTVADALEPVSFNDSETIVRQGEPGNDFYIIVE 465
R DE + +IL+ L+ + +L +A + F I+++G+ GN FY I
Sbjct: 99 RTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYL 158
Query: 464 GTAVVLQQRGAGGEAVE--VGRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARF 291
GT + + ++ L FGE+ +L R +T+ + + +DR F
Sbjct: 159 GTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF 218
>AL109965-6|CAI19249.1| 572|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 572
Score = 34.3 bits (75), Expect = 0.48
Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 8/120 (6%)
Frame = -2
Query: 626 RMYDEFLSRVSILESLEKWE------RLTVADALEPVSFNDSETIVRQGEPGNDFYIIVE 465
R DE + +IL+ L+ + +L +A + F I+++G+ GN FY I
Sbjct: 99 RTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYL 158
Query: 464 GTAVVLQQRGAGGEAVE--VGRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARF 291
GT + + ++ L FGE+ +L R +T+ + + +DR F
Sbjct: 159 GTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF 218
>AL109965-5|CAI19248.1| 576|Homo sapiens chromosome 20 open reading
frame 152 protein.
Length = 576
Score = 34.3 bits (75), Expect = 0.48
Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 8/120 (6%)
Frame = -2
Query: 626 RMYDEFLSRVSILESLEKWE------RLTVADALEPVSFNDSETIVRQGEPGNDFYIIVE 465
R DE + +IL+ L+ + +L +A + F I+++G+ GN FY I
Sbjct: 99 RTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYL 158
Query: 464 GTAVVLQQRGAGGEAVE--VGRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARF 291
GT + + ++ L FGE+ +L R +T+ + + +DR F
Sbjct: 159 GTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF 218
>AK057454-1|BAB71494.1| 572|Homo sapiens protein ( Homo sapiens
cDNA FLJ32892 fis, clone TESTI2004982, weakly similar to
CGMP-DEPENDENT PROTEIN KINASE 1, ALPHA ISOZYME (EC
2.7.1.37). ).
Length = 572
Score = 34.3 bits (75), Expect = 0.48
Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 8/120 (6%)
Frame = -2
Query: 626 RMYDEFLSRVSILESLEKWE------RLTVADALEPVSFNDSETIVRQGEPGNDFYIIVE 465
R DE + +IL+ L+ + +L +A + F I+++G+ GN FY I
Sbjct: 99 RTEDEIQAVCNILQVLDSYRNYAEPLQLLLAKVMRFERFGRRRVIIKKGQKGNSFYFIYL 158
Query: 464 GTAVVLQQRGAGGEAVE--VGRLGPSDYFGEIALLLDRPRAATVRAHGPLKCVKLDRARF 291
GT + + ++ L FGE+ +L R +T+ + + +DR F
Sbjct: 159 GTVAITKDEDGSSAFLDPHPKLLHKGSCFGEMDVLHASVRRSTIVCMEETEFLVVDREDF 218
>M84741-1|AAA52010.1| 690|Homo sapiens cGMP-gated cation channel
protein protein.
Length = 690
Score = 33.9 bits (74), Expect = 0.64
Identities = 23/81 (28%), Positives = 37/81 (45%)
Frame = -2
Query: 608 LSRVSILESLEKWERLTVADALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAG 429
L +V I E + + L+P ++ + I ++G+ G + YII EG V+ G
Sbjct: 474 LKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAVVADDGVT 533
Query: 428 GEAVEVGRLGPSDYFGEIALL 366
V L FGEI++L
Sbjct: 534 QFVV----LSDGSTFGEISIL 550
>AL365502-7|CAI14582.1| 1317|Homo sapiens patatin-like phospholipase
domain containing 7 protein.
Length = 1317
Score = 32.3 bits (70), Expect = 2.0
Identities = 23/81 (28%), Positives = 36/81 (44%)
Frame = -2
Query: 548 ALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIAL 369
AL+ V I RQG+ + YI++ G + ++ G + + G G D G +
Sbjct: 591 ALDWVEVEAGRAIYRQGDKSDCTYIMLSGRLRSVIRKDDGKKRL-AGEYGRGDLVGVVET 649
Query: 368 LLDRPRAATVRAHGPLKCVKL 306
L + RA TV A + KL
Sbjct: 650 LTHQARATTVHAVRDSELAKL 670
>AL365502-6|CAI14581.1| 1281|Homo sapiens patatin-like phospholipase
domain containing 7 protein.
Length = 1281
Score = 32.3 bits (70), Expect = 2.0
Identities = 23/81 (28%), Positives = 36/81 (44%)
Frame = -2
Query: 548 ALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIAL 369
AL+ V I RQG+ + YI++ G + ++ G + + G G D G +
Sbjct: 582 ALDWVEVEAGRAIYRQGDKSDCTYIMLSGRLRSVIRKDDGKKRL-AGEYGRGDLVGVVET 640
Query: 368 LLDRPRAATVRAHGPLKCVKL 306
L + RA TV A + KL
Sbjct: 641 LTHQARATTVHAVRDSELAKL 661
>AL365502-5|CAI14579.1| 923|Homo sapiens patatin-like phospholipase
domain containing 7 protein.
Length = 923
Score = 32.3 bits (70), Expect = 2.0
Identities = 23/81 (28%), Positives = 36/81 (44%)
Frame = -2
Query: 548 ALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIAL 369
AL+ V I RQG+ + YI++ G + ++ G + + G G D G +
Sbjct: 197 ALDWVEVEAGRAIYRQGDKSDCTYIMLSGRLRSVIRKDDGKKRL-AGEYGRGDLVGVVET 255
Query: 368 LLDRPRAATVRAHGPLKCVKL 306
L + RA TV A + KL
Sbjct: 256 LTHQARATTVHAVRDSELAKL 276
>AK125060-1|BAC86036.1| 1317|Homo sapiens protein ( Homo sapiens
cDNA FLJ43070 fis, clone BRTHA3009090, moderately
similar to Homo sapiens neuropathy target esterase
(NTE). ).
Length = 1317
Score = 32.3 bits (70), Expect = 2.0
Identities = 23/81 (28%), Positives = 36/81 (44%)
Frame = -2
Query: 548 ALEPVSFNDSETIVRQGEPGNDFYIIVEGTAVVLQQRGAGGEAVEVGRLGPSDYFGEIAL 369
AL+ V I RQG+ + YI++ G + ++ G + + G G D G +
Sbjct: 591 ALDWVEVEAGRAIYRQGDKSDCTYIMLSGRLRSVIRKDDGKKRL-AGEYGRGDLVGVVET 649
Query: 368 LLDRPRAATVRAHGPLKCVKL 306
L + RA TV A + KL
Sbjct: 650 LTHQARATTVHAVRDSELAKL 670
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,851,210
Number of Sequences: 237096
Number of extensions: 2063572
Number of successful extensions: 4669
Number of sequences better than 10.0: 88
Number of HSP's better than 10.0 without gapping: 4372
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4628
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9199990470
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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