Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner10n24f
(506 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X16396-1|CAA34431.1| 344|Homo sapiens protein ( Human mRNA for ... 172 5e-43
BC017054-1|AAH17054.2| 350|Homo sapiens methylenetetrahydrofola... 172 5e-43
BC001548-1|AAH01548.1| 344|Homo sapiens methylene tetrahydrofol... 172 5e-43
AC073263-5|AAX93061.1| 344|Homo sapiens unknown protein. 172 5e-43
AK223041-1|BAD96761.1| 344|Homo sapiens methylene tetrahydrofol... 171 2e-42
AK222826-1|BAD96546.1| 344|Homo sapiens methylene tetrahydrofol... 171 2e-42
BC037529-1|AAH37529.2| 106|Homo sapiens MTHFD2L protein protein. 105 1e-22
BC015062-1|AAH15062.1| 248|Homo sapiens methylenetetrahydrofola... 103 4e-22
J04031-1|AAA59574.1| 935|Homo sapiens MTHFD protein. 93 4e-19
BC050420-1|AAH50420.1| 935|Homo sapiens methylenetetrahydrofola... 93 4e-19
BC009806-1|AAH09806.1| 935|Homo sapiens methylenetetrahydrofola... 93 4e-19
BC032771-1|AAH32771.1| 146|Homo sapiens MTHFD2L protein protein. 91 2e-18
AK023167-1|BAB14441.1| 236|Homo sapiens ohydrolase (EC 1.5.1.15... 70 5e-12
BC110319-1|AAI10320.1| 900|Homo sapiens MTHFD1L protein protein. 56 5e-08
AY374131-1|AAQ82697.1| 275|Homo sapiens truncated C1-tetrahydro... 56 5e-08
AY374130-1|AAQ82696.1| 978|Homo sapiens C1-tetrahydrofolate syn... 56 5e-08
AL133260-2|CAI95678.1| 978|Homo sapiens methylenetetrahydrofola... 56 5e-08
AL117452-1|CAB55934.1| 917|Homo sapiens hypothetical protein pr... 56 5e-08
AL049694-4|CAI95775.1| 331|Homo sapiens methylenetetrahydrofola... 56 5e-08
AL049694-3|CAI95774.1| 978|Homo sapiens methylenetetrahydrofola... 56 5e-08
AL035086-8|CAI42795.1| 331|Homo sapiens methylenetetrahydrofola... 56 5e-08
AL035086-7|CAI42794.1| 978|Homo sapiens methylenetetrahydrofola... 56 5e-08
AB127387-1|BAD93193.1| 978|Homo sapiens mitochondrial C1-tetrah... 56 5e-08
AL035086-6|CAI42793.1| 114|Homo sapiens methylenetetrahydrofola... 51 2e-06
AL035086-5|CAI42791.1| 120|Homo sapiens methylenetetrahydrofola... 33 0.43
AL035086-4|CAI42792.1| 120|Homo sapiens methylenetetrahydrofola... 33 0.43
U78550-1|AAC51342.1| 328|Homo sapiens mucin MUC5B protein. 30 5.3
BC128260-1|AAI28261.1| 657|Homo sapiens VIT protein protein. 29 7.1
AY358338-1|AAQ88704.1| 678|Homo sapiens VIT protein. 29 7.1
AK056772-1|BAB71279.1| 693|Homo sapiens protein ( Homo sapiens ... 29 7.1
AF063833-1|AAL18263.1| 656|Homo sapiens vitrin protein. 29 7.1
AC007363-1|AAF19243.2| 693|Homo sapiens unknown protein. 29 7.1
M16801-1|AAA59571.1| 984|Homo sapiens MLR protein. 29 9.3
BC111758-1|AAI11759.1| 867|Homo sapiens NR3C2 protein protein. 29 9.3
AJ315514-1|CAC67405.1| 706|Homo sapiens mineralocorticoid recep... 29 9.3
AF068623-1|AAC63513.1| 440|Homo sapiens mineralocorticoid recep... 29 9.3
AB209056-1|BAD92293.1| 853|Homo sapiens nuclear receptor subfam... 29 9.3
>X16396-1|CAA34431.1| 344|Homo sapiens protein ( Human mRNA for
NAD-dependent methylene tetrahydrofolate dehydrogenase
cyclohydrolase (EC 1.5.1.15). ).
Length = 344
Score = 172 bits (419), Expect = 5e-43
Identities = 72/144 (50%), Positives = 115/144 (79%)
Frame = +2
Query: 71 ARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 250
A ++ G+ LA +IK+E++Q++ +WV+ GN+ P + I+VG++PASH+YV NK AA VG
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVG 90
Query: 251 IDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDG 430
I++ TI + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD+DG
Sbjct: 91 INSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDG 150
Query: 431 FHIINIGRLCVDLPTIVPATALAV 502
FH+IN+GR+C+D +++PAT V
Sbjct: 151 FHVINVGRMCLDQYSMLPATPWGV 174
>BC017054-1|AAH17054.2| 350|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 2, methenyltetrahydro
protein.
Length = 350
Score = 172 bits (419), Expect = 5e-43
Identities = 72/144 (50%), Positives = 115/144 (79%)
Frame = +2
Query: 71 ARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 250
A ++ G+ LA +IK+E++Q++ +WV+ GN+ P + I+VG++PASH+YV NK AA VG
Sbjct: 37 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVG 96
Query: 251 IDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDG 430
I++ TI + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD+DG
Sbjct: 97 INSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDG 156
Query: 431 FHIINIGRLCVDLPTIVPATALAV 502
FH+IN+GR+C+D +++PAT V
Sbjct: 157 FHVINVGRMCLDQYSMLPATPWGV 180
>BC001548-1|AAH01548.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2, precursor protein.
Length = 344
Score = 172 bits (419), Expect = 5e-43
Identities = 72/144 (50%), Positives = 115/144 (79%)
Frame = +2
Query: 71 ARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 250
A ++ G+ LA +IK+E++Q++ +WV+ GN+ P + I+VG++PASH+YV NK AA VG
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVG 90
Query: 251 IDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDG 430
I++ TI + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD+DG
Sbjct: 91 INSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDG 150
Query: 431 FHIINIGRLCVDLPTIVPATALAV 502
FH+IN+GR+C+D +++PAT V
Sbjct: 151 FHVINVGRMCLDQYSMLPATPWGV 174
>AC073263-5|AAX93061.1| 344|Homo sapiens unknown protein.
Length = 344
Score = 172 bits (419), Expect = 5e-43
Identities = 72/144 (50%), Positives = 115/144 (79%)
Frame = +2
Query: 71 ARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 250
A ++ G+ LA +IK+E++Q++ +WV+ GN+ P + I+VG++PASH+YV NK AA VG
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVVG 90
Query: 251 IDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDG 430
I++ TI + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD+DG
Sbjct: 91 INSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDG 150
Query: 431 FHIINIGRLCVDLPTIVPATALAV 502
FH+IN+GR+C+D +++PAT V
Sbjct: 151 FHVINVGRMCLDQYSMLPATPWGV 174
>AK223041-1|BAD96761.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2 precursor variant protein.
Length = 344
Score = 171 bits (415), Expect = 2e-42
Identities = 71/144 (49%), Positives = 114/144 (79%)
Frame = +2
Query: 71 ARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 250
A ++ G+ LA +IK+E++Q++ +WV+ GN+ P + I+VG++PASH+YV NK AA G
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILVGENPASHSYVLNKTRAAAVAG 90
Query: 251 IDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDG 430
I++ TI + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD+DG
Sbjct: 91 INSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDG 150
Query: 431 FHIINIGRLCVDLPTIVPATALAV 502
FH+IN+GR+C+D +++PAT V
Sbjct: 151 FHVINVGRMCLDQYSMLPATPWGV 174
>AK222826-1|BAD96546.1| 344|Homo sapiens methylene tetrahydrofolate
dehydrogenase 2 precursor variant protein.
Length = 344
Score = 171 bits (415), Expect = 2e-42
Identities = 71/144 (49%), Positives = 114/144 (79%)
Frame = +2
Query: 71 ARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVG 250
A ++ G+ LA +IK+E++Q++ +WV+ GN+ P + I+ G++PASH+YV NK AA VG
Sbjct: 31 AVVISGRKLAQQIKQEVRQEVEEWVASGNKRPHLSVILAGENPASHSYVLNKTRAAAVVG 90
Query: 251 IDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDG 430
I++ TI + + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD+DG
Sbjct: 91 INSETIMKPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDG 150
Query: 431 FHIINIGRLCVDLPTIVPATALAV 502
FH+IN+GR+C+D +++PAT V
Sbjct: 151 FHVINVGRMCLDQYSMLPATPWGV 174
>BC037529-1|AAH37529.2| 106|Homo sapiens MTHFD2L protein protein.
Length = 106
Score = 105 bits (251), Expect = 1e-22
Identities = 48/95 (50%), Positives = 67/95 (70%)
Frame = +2
Query: 95 LAMEIKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINR 274
+A I+KE+++ + WVSLGNR P + I+VGD+PASHTYVRNK+ AA VGI + I +
Sbjct: 1 MAKHIQKEIQRGVESWVSLGNRRPHLSIILVGDNPASHTYVRNKIRAASAVGICSELILK 60
Query: 275 DSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTI 379
D+++E+LL LN D V GILVQLP+P+ +
Sbjct: 61 PKDVSQEELLDVTDQLNMDPRVSGILVQLPLPEAV 95
>BC015062-1|AAH15062.1| 248|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 2, methenyltetrahydro
protein.
Length = 248
Score = 103 bits (247), Expect = 4e-22
Identities = 41/77 (53%), Positives = 65/77 (84%)
Frame = +2
Query: 272 RDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIG 451
+ + I+EE+LL+ I LN D++VDG+LVQLP+P+ I+ERR+C+A++P+KD+DGFH+IN+G
Sbjct: 2 KPASISEEELLNLINKLNNDDNVDGLLVQLPLPEHIDERRICNAVSPDKDVDGFHVINVG 61
Query: 452 RLCVDLPTIVPATALAV 502
R+C+D +++PAT V
Sbjct: 62 RMCLDQYSMLPATPWGV 78
>J04031-1|AAA59574.1| 935|Homo sapiens MTHFD protein.
Length = 935
Score = 93.5 bits (222), Expect = 4e-19
Identities = 52/132 (39%), Positives = 80/132 (60%), Gaps = 3/132 (2%)
Frame = +2
Query: 71 ARILDGKALAMEIKKELKQKIAQWVS-LGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFV 247
A IL+GK ++ +I+ LK ++ Q + P + + VG+ S+ Y+ K++AA+ +
Sbjct: 4 AEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEI 63
Query: 248 GIDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPV--PDTINERRVCDAIAPEKD 421
GI A I TE +++ I +LNED++V G LVQLP+ ++IN V +AIAPEKD
Sbjct: 64 GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
Query: 422 IDGFHIINIGRL 457
+DG IN GRL
Sbjct: 124 VDGLTSINAGRL 135
>BC050420-1|AAH50420.1| 935|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1, methenyltetrahydro
protein.
Length = 935
Score = 93.5 bits (222), Expect = 4e-19
Identities = 52/132 (39%), Positives = 80/132 (60%), Gaps = 3/132 (2%)
Frame = +2
Query: 71 ARILDGKALAMEIKKELKQKIAQWVS-LGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFV 247
A IL+GK ++ +I+ LK ++ Q + P + + VG+ S+ Y+ K++AA+ +
Sbjct: 4 AEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEI 63
Query: 248 GIDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPV--PDTINERRVCDAIAPEKD 421
GI A I TE +++ I +LNED++V G LVQLP+ ++IN V +AIAPEKD
Sbjct: 64 GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
Query: 422 IDGFHIINIGRL 457
+DG IN GRL
Sbjct: 124 VDGLTSINAGRL 135
>BC009806-1|AAH09806.1| 935|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1, methenyltetrahydro
protein.
Length = 935
Score = 93.5 bits (222), Expect = 4e-19
Identities = 52/132 (39%), Positives = 80/132 (60%), Gaps = 3/132 (2%)
Frame = +2
Query: 71 ARILDGKALAMEIKKELKQKIAQWVS-LGNRAPTIRCIIVGDDPASHTYVRNKVEAAKFV 247
A IL+GK ++ +I+ LK ++ Q + P + + VG+ S+ Y+ K++AA+ +
Sbjct: 4 AEILNGKEISAQIRARLKNQVTQLKEQVPGFTPRLAILQVGNRDDSNLYINVKLKAAEEI 63
Query: 248 GIDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPV--PDTINERRVCDAIAPEKD 421
GI A I TE +++ I +LNED++V G LVQLP+ ++IN V +AIAPEKD
Sbjct: 64 GIKATHIKLPRTTTESEVMKYITSLNEDSTVHGFLVQLPLDSENSINTEEVINAIAPEKD 123
Query: 422 IDGFHIINIGRL 457
+DG IN GRL
Sbjct: 124 VDGLTSINAGRL 135
>BC032771-1|AAH32771.1| 146|Homo sapiens MTHFD2L protein protein.
Length = 146
Score = 91.1 bits (216), Expect = 2e-18
Identities = 39/58 (67%), Positives = 49/58 (84%)
Frame = +2
Query: 329 DNSVDGILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRLCVDLPTIVPATALAV 502
D V GILVQLP+PD ++ER +C+ IAPEKD+DGFHIINIGRLC+D +++PATA AV
Sbjct: 2 DPRVSGILVQLPLPDHVDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAV 59
>AK023167-1|BAB14441.1| 236|Homo sapiens ohydrolase (EC 1.5.1.15).
protein.
Length = 236
Score = 69.7 bits (163), Expect = 5e-12
Identities = 28/42 (66%), Positives = 37/42 (88%)
Frame = +2
Query: 377 INERRVCDAIAPEKDIDGFHIINIGRLCVDLPTIVPATALAV 502
++ER +C+ IAPEKD+DGFHIINIGRLC+D +++PATA AV
Sbjct: 42 VDERTICNGIAPEKDVDGFHIINIGRLCLDQHSLIPATASAV 83
>BC110319-1|AAI10320.1| 900|Homo sapiens MTHFD1L protein protein.
Length = 900
Score = 56.4 bits (130), Expect = 5e-08
Identities = 32/98 (32%), Positives = 52/98 (53%)
Frame = +2
Query: 164 PTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVD 343
P + I GDD +N E A G++ I D +E +++ EI +NED V
Sbjct: 20 PVLAIIQAGDDNLMQEINQNLAEEA---GLNITHICLPPDSSEAEIIDEILKINEDTRVH 76
Query: 344 GILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 77 GLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKL 112
>AY374131-1|AAQ82697.1| 275|Homo sapiens truncated
C1-tetrahydrofolate synthase protein.
Length = 275
Score = 56.4 bits (130), Expect = 5e-08
Identities = 32/98 (32%), Positives = 52/98 (53%)
Frame = +2
Query: 164 PTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVD 343
P + I GDD +N E A G++ I D +E +++ EI +NED V
Sbjct: 98 PVLAIIQAGDDNLMQEINQNLAEEA---GLNITHICLPPDSSEAEIIDEILKINEDTRVH 154
Query: 344 GILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 155 GLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKL 190
>AY374130-1|AAQ82696.1| 978|Homo sapiens C1-tetrahydrofolate
synthase protein.
Length = 978
Score = 56.4 bits (130), Expect = 5e-08
Identities = 32/98 (32%), Positives = 52/98 (53%)
Frame = +2
Query: 164 PTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVD 343
P + I GDD +N E A G++ I D +E +++ EI +NED V
Sbjct: 98 PVLAIIQAGDDNLMQEINQNLAEEA---GLNITHICLPPDSSEAEIIDEILKINEDTRVH 154
Query: 344 GILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 155 GLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKL 190
>AL133260-2|CAI95678.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 56.4 bits (130), Expect = 5e-08
Identities = 32/98 (32%), Positives = 52/98 (53%)
Frame = +2
Query: 164 PTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVD 343
P + I GDD +N E A G++ I D +E +++ EI +NED V
Sbjct: 98 PVLAIIQAGDDNLMQEINQNLAEEA---GLNITHICLPPDSSEAEIIDEILKINEDTRVH 154
Query: 344 GILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 155 GLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKL 190
>AL117452-1|CAB55934.1| 917|Homo sapiens hypothetical protein
protein.
Length = 917
Score = 56.4 bits (130), Expect = 5e-08
Identities = 32/98 (32%), Positives = 52/98 (53%)
Frame = +2
Query: 164 PTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVD 343
P + I GDD +N E A G++ I D +E +++ EI +NED V
Sbjct: 37 PVLAIIQAGDDNLMQEINQNLAEEA---GLNITHICLPPDSSEAEIIDEILKINEDTRVH 93
Query: 344 GILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 94 GLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKL 129
>AL049694-4|CAI95775.1| 331|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 331
Score = 56.4 bits (130), Expect = 5e-08
Identities = 32/98 (32%), Positives = 52/98 (53%)
Frame = +2
Query: 164 PTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVD 343
P + I GDD +N E A G++ I D +E +++ EI +NED V
Sbjct: 57 PVLAIIQAGDDNLMQEINQNLAEEA---GLNITHICLPPDSSEAEIIDEILKINEDTRVH 113
Query: 344 GILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 114 GLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKL 149
>AL049694-3|CAI95774.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 56.4 bits (130), Expect = 5e-08
Identities = 32/98 (32%), Positives = 52/98 (53%)
Frame = +2
Query: 164 PTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVD 343
P + I GDD +N E A G++ I D +E +++ EI +NED V
Sbjct: 98 PVLAIIQAGDDNLMQEINQNLAEEA---GLNITHICLPPDSSEAEIIDEILKINEDTRVH 154
Query: 344 GILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 155 GLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKL 190
>AL035086-8|CAI42795.1| 331|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 331
Score = 56.4 bits (130), Expect = 5e-08
Identities = 32/98 (32%), Positives = 52/98 (53%)
Frame = +2
Query: 164 PTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVD 343
P + I GDD +N E A G++ I D +E +++ EI +NED V
Sbjct: 57 PVLAIIQAGDDNLMQEINQNLAEEA---GLNITHICLPPDSSEAEIIDEILKINEDTRVH 113
Query: 344 GILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 114 GLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKL 149
>AL035086-7|CAI42794.1| 978|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 978
Score = 56.4 bits (130), Expect = 5e-08
Identities = 32/98 (32%), Positives = 52/98 (53%)
Frame = +2
Query: 164 PTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVD 343
P + I GDD +N E A G++ I D +E +++ EI +NED V
Sbjct: 98 PVLAIIQAGDDNLMQEINQNLAEEA---GLNITHICLPPDSSEAEIIDEILKINEDTRVH 154
Query: 344 GILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 155 GLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKL 190
>AB127387-1|BAD93193.1| 978|Homo sapiens mitochondrial
C1-tetrahydrofolate synthetase protein.
Length = 978
Score = 56.4 bits (130), Expect = 5e-08
Identities = 32/98 (32%), Positives = 52/98 (53%)
Frame = +2
Query: 164 PTIRCIIVGDDPASHTYVRNKVEAAKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVD 343
P + I GDD +N E A G++ I D +E +++ EI +NED V
Sbjct: 98 PVLAIIQAGDDNLMQEINQNLAEEA---GLNITHICLPPDSSEAEIIDEILKINEDTRVH 154
Query: 344 GILVQLPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
G+ +Q + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 155 GLALQ--ISENLFSNKVLNALKPEKDVDGVTDINLGKL 190
>AL035086-6|CAI42793.1| 114|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 114
Score = 51.2 bits (117), Expect = 2e-06
Identities = 25/74 (33%), Positives = 44/74 (59%)
Frame = +2
Query: 236 AKFVGIDALTINRDSDITEEQLLSEIQNLNEDNSVDGILVQLPVPDTINERRVCDAIAPE 415
A+ G++ I D +E +++ EI +NED V G+ +Q + + + +V +A+ PE
Sbjct: 9 AEEAGLNITHICLPPDSSEAEIIDEILKINEDTRVHGLALQ--ISENLFSNKVLNALKPE 66
Query: 416 KDIDGFHIINIGRL 457
KD+DG IN+G+L
Sbjct: 67 KDVDGVTDINLGKL 80
>AL035086-5|CAI42791.1| 120|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 120
Score = 33.5 bits (73), Expect = 0.43
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 359 LPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
L + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 2 LQISENLFSNKVLNALKPEKDVDGVTDINLGKL 34
>AL035086-4|CAI42792.1| 120|Homo sapiens methylenetetrahydrofolate
dehydrogenase (NADP+ dependent) 1-like protein.
Length = 120
Score = 33.5 bits (73), Expect = 0.43
Identities = 13/33 (39%), Positives = 22/33 (66%)
Frame = +2
Query: 359 LPVPDTINERRVCDAIAPEKDIDGFHIINIGRL 457
L + + + +V +A+ PEKD+DG IN+G+L
Sbjct: 3 LQISENLFSNKVLNALKPEKDVDGVTDINLGKL 35
>U78550-1|AAC51342.1| 328|Homo sapiens mucin MUC5B protein.
Length = 328
Score = 29.9 bits (64), Expect = 5.3
Identities = 27/100 (27%), Positives = 39/100 (39%), Gaps = 3/100 (3%)
Frame = -3
Query: 504 TTANAVAGTMVGRSTHSLPMLIMWK--PSISFSGAIASQTLLSLIVSGTG-NWTRIPSTL 334
++ A AGT +T + P +I WK P S A A L S + T ++T IPS+
Sbjct: 49 SSTQATAGTPHVTTTATTPTVISWKATPFSSPGTATALPALRSTATTPTATSFTAIPSSS 108
Query: 333 LSSFKFWXXXXXXXXXXXXXXXIVNASMPTNFAASTLFLT 214
L + W +S P ST+ T
Sbjct: 109 LGT--TWTRLSQTTTPTATMSTATPSSTPETAHTSTVLTT 146
>BC128260-1|AAI28261.1| 657|Homo sapiens VIT protein protein.
Length = 657
Score = 29.5 bits (63), Expect = 7.1
Identities = 12/34 (35%), Positives = 21/34 (61%)
Frame = +2
Query: 107 IKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASH 208
I+K+L +AQ + +G P + + GD+PA+H
Sbjct: 290 IQKQLLADVAQALDIGPAGPLMGVVQYGDNPATH 323
>AY358338-1|AAQ88704.1| 678|Homo sapiens VIT protein.
Length = 678
Score = 29.5 bits (63), Expect = 7.1
Identities = 12/34 (35%), Positives = 21/34 (61%)
Frame = +2
Query: 107 IKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASH 208
I+K+L +AQ + +G P + + GD+PA+H
Sbjct: 311 IQKQLLADVAQALDIGPAGPLMGVVQYGDNPATH 344
>AK056772-1|BAB71279.1| 693|Homo sapiens protein ( Homo sapiens
cDNA FLJ32210 fis, clone PLACE6003383, weakly similar to
COCHLIN PRECURSOR. ).
Length = 693
Score = 29.5 bits (63), Expect = 7.1
Identities = 12/34 (35%), Positives = 21/34 (61%)
Frame = +2
Query: 107 IKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASH 208
I+K+L +AQ + +G P + + GD+PA+H
Sbjct: 326 IQKQLLADVAQALDIGPAGPLMGVVQYGDNPATH 359
>AF063833-1|AAL18263.1| 656|Homo sapiens vitrin protein.
Length = 656
Score = 29.5 bits (63), Expect = 7.1
Identities = 12/34 (35%), Positives = 21/34 (61%)
Frame = +2
Query: 107 IKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASH 208
I+K+L +AQ + +G P + + GD+PA+H
Sbjct: 289 IQKQLLADVAQALDIGPAGPLMGVVQYGDNPATH 322
>AC007363-1|AAF19243.2| 693|Homo sapiens unknown protein.
Length = 693
Score = 29.5 bits (63), Expect = 7.1
Identities = 12/34 (35%), Positives = 21/34 (61%)
Frame = +2
Query: 107 IKKELKQKIAQWVSLGNRAPTIRCIIVGDDPASH 208
I+K+L +AQ + +G P + + GD+PA+H
Sbjct: 326 IQKQLLADVAQALDIGPAGPLMGVVQYGDNPATH 359
>M16801-1|AAA59571.1| 984|Homo sapiens MLR protein.
Length = 984
Score = 29.1 bits (62), Expect = 9.3
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 8 HLTSKMRSHTYIDSLGS-ASIMARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCII 184
HL+S +T ++S S + +R DG + I + + + VS G+ P+ C++
Sbjct: 546 HLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLV 605
Query: 185 VGDDPASHTY 214
GD+ + Y
Sbjct: 606 CGDEASGCHY 615
>BC111758-1|AAI11759.1| 867|Homo sapiens NR3C2 protein protein.
Length = 867
Score = 29.1 bits (62), Expect = 9.3
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 8 HLTSKMRSHTYIDSLGS-ASIMARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCII 184
HL+S +T ++S S + +R DG + I + + + VS G+ P+ C++
Sbjct: 546 HLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLV 605
Query: 185 VGDDPASHTY 214
GD+ + Y
Sbjct: 606 CGDEASGCHY 615
>AJ315514-1|CAC67405.1| 706|Homo sapiens mineralocorticoid receptor
delta protein.
Length = 706
Score = 29.1 bits (62), Expect = 9.3
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 8 HLTSKMRSHTYIDSLGS-ASIMARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCII 184
HL+S +T ++S S + +R DG + I + + + VS G+ P+ C++
Sbjct: 546 HLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLV 605
Query: 185 VGDDPASHTY 214
GD+ + Y
Sbjct: 606 CGDEASGCHY 615
>AF068623-1|AAC63513.1| 440|Homo sapiens mineralocorticoid receptor
protein.
Length = 440
Score = 29.1 bits (62), Expect = 9.3
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 8 HLTSKMRSHTYIDSLGS-ASIMARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCII 184
HL+S +T ++S S + +R DG + I + + + VS G+ P+ C++
Sbjct: 2 HLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLV 61
Query: 185 VGDDPASHTY 214
GD+ + Y
Sbjct: 62 CGDEASGCHY 71
>AB209056-1|BAD92293.1| 853|Homo sapiens nuclear receptor subfamily
3, group C, member 2 variant protein.
Length = 853
Score = 29.1 bits (62), Expect = 9.3
Identities = 18/70 (25%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +2
Query: 8 HLTSKMRSHTYIDSLGS-ASIMARILDGKALAMEIKKELKQKIAQWVSLGNRAPTIRCII 184
HL+S +T ++S S + +R DG + I + + + VS G+ P+ C++
Sbjct: 415 HLSSFPPVNTLVESWKSHGDLSSRRSDGYPVLEYIPENVSSSTLRSVSTGSSRPSKICLV 474
Query: 185 VGDDPASHTY 214
GD+ + Y
Sbjct: 475 CGDEASGCHY 484
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 80,188,780
Number of Sequences: 237096
Number of extensions: 1710058
Number of successful extensions: 3323
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 3239
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3319
length of database: 76,859,062
effective HSP length: 85
effective length of database: 56,705,902
effective search space used: 4706589866
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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