Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner10n09r
(755 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA ... 287 3e-76
UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to 3-hydroxya... 237 2e-61
UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30; Coelom... 236 4e-61
UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella ve... 210 2e-53
UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|R... 192 8e-48
UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3; ... 182 1e-44
UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 161 2e-38
UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5; Alphaproteobacter... 159 9e-38
UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 155 8e-37
UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain ... 151 2e-35
UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 151 2e-35
UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 144 2e-33
UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 143 5e-33
UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 142 6e-33
UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 139 6e-32
UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 138 1e-31
UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 131 2e-29
UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1; Bre... 118 2e-25
UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 112 1e-23
UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 111 2e-23
UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3; ... 109 7e-23
UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 106 5e-22
UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 105 9e-22
UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 105 9e-22
UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA dehyd... 104 3e-21
UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 103 4e-21
UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 103 6e-21
UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 100 4e-20
UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 99 6e-20
UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1; ... 99 6e-20
UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4; S... 97 5e-19
UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24; ... 96 1e-18
UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 - Cl... 96 1e-18
UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1; ... 95 2e-18
UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 93 5e-18
UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precurs... 93 9e-18
UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 92 1e-17
UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5; Tri... 92 1e-17
UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 92 2e-17
UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 91 2e-17
UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4; Trichoco... 91 3e-17
UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 90 6e-17
UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2... 90 6e-17
UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;... 89 8e-17
UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 89 1e-16
UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; B... 89 1e-16
UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9; B... 87 3e-16
UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 87 4e-16
UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; S... 87 4e-16
UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 86 1e-15
UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 85 1e-15
UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 83 5e-15
UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 83 7e-15
UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 83 9e-15
UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 82 2e-14
UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; B... 79 9e-14
UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Re... 79 2e-13
UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 78 2e-13
UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,... 78 3e-13
UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 78 3e-13
UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1; ... 78 3e-13
UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 77 4e-13
UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 77 4e-13
UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 77 5e-13
UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 74 3e-12
UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 73 8e-12
UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 73 1e-11
UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5; A... 69 9e-11
UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 68 2e-10
UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 67 5e-10
UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; A... 66 7e-10
UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 66 9e-10
UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA dehydrogenase/3-hydro... 66 9e-10
UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 66 9e-10
UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 66 1e-09
UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 65 2e-09
UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 65 2e-09
UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase N... 64 3e-09
UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6... 64 3e-09
UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8... 64 4e-09
UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 64 5e-09
UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 64 5e-09
UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 63 6e-09
UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 63 6e-09
UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 63 8e-09
UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like pr... 63 8e-09
UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 62 1e-08
UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; H... 62 1e-08
UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase r... 62 1e-08
UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16; ... 61 3e-08
UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 61 3e-08
UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 60 6e-08
UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 60 8e-08
UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 60 8e-08
UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3... 59 1e-07
UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 59 1e-07
UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 58 2e-07
UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase; ... 58 2e-07
UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 58 2e-07
UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 58 2e-07
UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 58 2e-07
UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 58 2e-07
UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 58 2e-07
UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 58 3e-07
UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 58 3e-07
UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; c... 58 3e-07
UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 57 4e-07
UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase, m... 57 4e-07
UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenas... 57 5e-07
UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 57 5e-07
UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2... 57 5e-07
UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 57 5e-07
UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 56 7e-07
UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 56 7e-07
UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 56 9e-07
UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 56 9e-07
UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 56 1e-06
UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 55 2e-06
UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 55 2e-06
UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 55 2e-06
UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex t... 55 2e-06
UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8; A... 54 3e-06
UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD bi... 54 3e-06
UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 54 3e-06
UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 54 3e-06
UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular organi... 54 4e-06
UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 54 4e-06
UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 54 5e-06
UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC... 54 5e-06
UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA dehydroge... 54 5e-06
UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subun... 53 7e-06
UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 53 9e-06
UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 53 9e-06
UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome. prec... 53 9e-06
UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB... 52 1e-05
UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein ... 52 1e-05
UniRef50_O69856 Cluster: Fatty acid oxidation complex alpha-subu... 52 2e-05
UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 52 2e-05
UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 52 2e-05
UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; A... 52 2e-05
UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5... 51 3e-05
UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 51 4e-05
UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;... 51 4e-05
UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48; ... 51 4e-05
UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10; ... 51 4e-05
UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 51 4e-05
UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 51 4e-05
UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 51 4e-05
UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n... 50 5e-05
UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 50 5e-05
UniRef50_Q5P607 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 50 6e-05
UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 50 6e-05
UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA dehy... 50 6e-05
UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA dehydroge... 50 6e-05
UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=3... 50 8e-05
UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family ... 50 8e-05
UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;... 50 8e-05
UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein NCU043... 50 8e-05
UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1; ... 50 8e-05
UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4... 49 1e-04
UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1... 49 1e-04
UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 49 1e-04
UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:... 49 1e-04
UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9; G... 49 1e-04
UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit ... 48 2e-04
UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 2e-04
UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putati... 48 2e-04
UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA... 48 3e-04
UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 48 3e-04
UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;... 48 3e-04
UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 48 3e-04
UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit, mit... 48 3e-04
UniRef50_Q1YHC5 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 47 4e-04
UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 47 4e-04
UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 47 4e-04
UniRef50_Q5LVD0 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 47 6e-04
UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit ... 47 6e-04
UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2; Alphapr... 47 6e-04
UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole gen... 47 6e-04
UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:... 47 6e-04
UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit al... 46 8e-04
UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 46 0.001
UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; P... 46 0.001
UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3... 46 0.001
UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 46 0.001
UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13; c... 46 0.001
UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 46 0.001
UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1; ... 46 0.001
UniRef50_Q5LVG3 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 45 0.002
UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 45 0.002
UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 45 0.002
UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep: ... 45 0.002
UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 45 0.002
UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 45 0.002
UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation m... 45 0.002
UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit al... 45 0.002
UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation m... 44 0.003
UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 44 0.003
UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 44 0.003
UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 44 0.004
UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 44 0.004
UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase NAD-bin... 44 0.004
UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 44 0.004
UniRef50_Q5V581 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 44 0.004
UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9... 44 0.004
UniRef50_Q8EYS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=4; L... 44 0.005
UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogena... 44 0.005
UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;... 44 0.005
UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 44 0.005
UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius s... 43 0.007
UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;... 43 0.007
UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2; Si... 43 0.007
UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;... 43 0.007
UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit al... 43 0.007
UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 43 0.009
UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 43 0.009
UniRef50_A3T2M8 Cluster: Enoyl-CoA hydratase/isomerase/3-hydroxy... 43 0.009
UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 42 0.012
UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 42 0.012
UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella ve... 42 0.012
UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2; A... 42 0.016
UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;... 42 0.016
UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; H... 42 0.016
UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 42 0.016
UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-C... 42 0.016
UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 42 0.022
UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1... 41 0.029
UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 41 0.029
UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 41 0.029
UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA dehydroge... 41 0.038
UniRef50_Q47DJ5 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 41 0.038
UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; V... 41 0.038
UniRef50_Q0CYI1 Cluster: Predicted protein; n=1; Aspergillus ter... 41 0.038
UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; c... 41 0.038
UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit al... 41 0.038
UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n... 40 0.050
UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenas... 40 0.050
UniRef50_A2QA05 Cluster: Catalytic activity:; n=4; Trichocomacea... 40 0.050
UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 40 0.066
UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase prec... 40 0.066
UniRef50_Q4Q3S6 Cluster: Enoyl-CoA hydratase/Enoyl-CoA isomerase... 40 0.088
UniRef50_Q4DMG1 Cluster: Short chain 3-hydroxyacyl-coa dehydroge... 40 0.088
UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation c... 39 0.12
UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase, C-term... 39 0.15
UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2; Bord... 38 0.20
UniRef50_Q0SA65 Cluster: Possible 3-hydroxybutyryl-CoA dehydroge... 38 0.27
UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;... 38 0.35
UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 38 0.35
UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;... 37 0.47
UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7; X... 37 0.47
UniRef50_A3TT55 Cluster: Putative fatty acid oxidation complex a... 37 0.47
UniRef50_A1TEA9 Cluster: Putative uncharacterized protein; n=2; ... 37 0.62
UniRef50_Q01UM7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; S... 36 0.82
UniRef50_Q7RN38 Cluster: Putative uncharacterized protein PY0198... 36 0.82
UniRef50_Q1LBV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 36 1.1
UniRef50_A4BGI3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; R... 36 1.4
UniRef50_A6FFH1 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenas... 35 1.9
UniRef50_A6GIL3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1; P... 35 2.5
UniRef50_A3VIL7 Cluster: Enoyl-CoA hydratase/isomerase:3-hydroxy... 35 2.5
UniRef50_Q05FN5 Cluster: Dihydrodipicolinate synthase; n=1; Cand... 34 3.3
UniRef50_A7LYA0 Cluster: Putative uncharacterized protein; n=1; ... 34 3.3
UniRef50_Q0UKG0 Cluster: Predicted protein; n=1; Phaeosphaeria n... 34 3.3
UniRef50_Q5NW50 Cluster: DitN-like 3-hydroxyacyl-CoA dehydrogena... 34 4.4
UniRef50_Q11BV6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD-bi... 34 4.4
UniRef50_Q4FL01 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3; B... 33 5.8
UniRef50_O96157 Cluster: Putative uncharacterized protein PFB028... 33 7.6
UniRef50_A2EYT5 Cluster: Putative uncharacterized protein; n=1; ... 33 7.6
>UniRef50_Q9VXI1 Cluster: CG9914-PA; n=5; Diptera|Rep: CG9914-PA -
Drosophila melanogaster (Fruit fly)
Length = 315
Score = 287 bits (703), Expect = 3e-76
Identities = 139/233 (59%), Positives = 168/233 (72%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
VKGAIFVQEC+PE LDLKK +++ LD+VV NTI S LK+K+ V+VS
Sbjct: 84 VKGAIFVQECIPERLDLKKALYKQLDAVVGPNTILSSSTSTFLPSLFSADLKNKANVLVS 143
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
HPVNPPYYVPLVEIVPAPWTKPE KKTR +MEEIGQ+PV+L+REI+GF LNRIQYAIL+
Sbjct: 144 HPVNPPYYVPLVEIVPAPWTKPEWVKKTRALMEEIGQKPVTLSREIEGFALNRIQYAILN 203
Query: 388 EVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRVSN 209
E WRL VMS GLG RYAFLG LETAHLNAEGM +Y +RY TIY VS
Sbjct: 204 ETWRLVEAGILNVKDIDSVMSNGLGPRYAFLGPLETAHLNAEGMANYFERYSNTIYAVSE 263
Query: 208 EMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKEMNK 50
MGP P+M V +QL ++VP+++L RRN+RD CL +LS+LK ++N+
Sbjct: 264 TMGPTPKM-EGPVAVEVAKQLGEMVPLDQLAQRRNYRDNCLTQLSILKNKLNQ 315
>UniRef50_UPI0000588BF0 Cluster: PREDICTED: similar to
3-hydroxyacyl-coa dehyrogenase; n=5; Coelomata|Rep:
PREDICTED: similar to 3-hydroxyacyl-coa dehyrogenase -
Strongylocentrotus purpuratus
Length = 316
Score = 237 bits (581), Expect = 2e-61
Identities = 110/235 (46%), Positives = 149/235 (63%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ GA FVQECV E L++K+KVF ++ V D I +E LK ++Q I+
Sbjct: 81 ALAGASFVQECVFEKLEVKQKVFSEMEQYVSDGAILSSSSSCIMPSQFTENLKRRNQCII 140
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
SHP+NPPYY PLVEI+PAPWT +TR IME +GQ PV+L +E+ GF NRIQYAI+
Sbjct: 141 SHPINPPYYAPLVEIIPAPWTDQSAIDRTRTIMESVGQVPVTLKKEVPGFAANRIQYAII 200
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRVS 212
EVWRL VMS GLG+RYAFLG LE HLNAEGMQSY++RY ++I V
Sbjct: 201 AEVWRLVEGGVLSADDMDKVMSAGLGLRYAFLGPLEVMHLNAEGMQSYMERYTQSIEHVL 260
Query: 211 NEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKEMNKK 47
GP P T + ++++ +P++KL++RR WRD L L+ LK+++ ++
Sbjct: 261 GNFGPTPTF-TGSGLEQIIKEMDAKIPLDKLEERRQWRDTRLAALAKLKRDLERE 314
>UniRef50_Q9Y2S2 Cluster: Lambda-crystallin homolog; n=30;
Coelomata|Rep: Lambda-crystallin homolog - Homo sapiens
(Human)
Length = 319
Score = 236 bits (578), Expect = 4e-61
Identities = 118/235 (50%), Positives = 146/235 (62%), Gaps = 3/235 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+GA+ +QECVPE+L+LKKK+F LDS++DD I GL H Q IV
Sbjct: 84 AVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMPSKLFAGLVHVKQCIV 143
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+HPVNPPYY+PLVE+VP P T P +T +M++IGQ P+ + +E+ GFVLNR+QYAI+
Sbjct: 144 AHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQKEVAGFVLNRLQYAII 203
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRVS 212
E WRL VMSEGLGMRYAF+G LET HLNAEGM SY DRY E I V
Sbjct: 204 SEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYCDRYSEGIKHVL 263
Query: 211 NEMGPAP---RMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKEM 56
GP P R T K +C ++ E L RR WRD CLMRL+ LK ++
Sbjct: 264 QTFGPIPEFSRATAEKVNQDMCMKVPD--DPEHLAARRQWRDECLMRLAKLKSQV 316
>UniRef50_A7SBT1 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 322
Score = 210 bits (514), Expect = 2e-53
Identities = 100/233 (42%), Positives = 149/233 (63%), Gaps = 2/233 (0%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDN-TIXXXXXXXXXXXXXSEGLKHKSQVI 575
A+ G +VQEC PENL+LKKKVFQNL++ + + I +E L+ + + I
Sbjct: 87 ALNGVFYVQECTPENLELKKKVFQNLEATLSSSEVILASSTSCIMPSKFTESLQLRQRCI 146
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
V+HP+NPPYYVPLVE++PAPWT V ++T ++M++IGQ PV L +E +GF++NR+QYA+
Sbjct: 147 VAHPINPPYYVPLVEVIPAPWTDASVIEQTIKLMKDIGQSPVLLKKETNGFIVNRLQYAL 206
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYR- 218
+ E WRL M+EGLG+RY+ +G ET HLNA+G++ Y RYG+ I+
Sbjct: 207 IAEAWRLVEEGICSPEDVDTTMTEGLGLRYSLIGPFETMHLNADGIRDYCQRYGDNIHHI 266
Query: 217 VSNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKE 59
V N P+P T + ++V E L + +P++KL DRR RD L L++ + +
Sbjct: 267 VKNSTIPSP--LTGATLDTVEEDLCQTMPLDKLSDRRALRDRRLAALAVFRAQ 317
>UniRef50_Q1RLR0 Cluster: LOC570274 protein; n=4; Clupeocephala|Rep:
LOC570274 protein - Danio rerio (Zebrafish) (Brachydanio
rerio)
Length = 327
Score = 192 bits (468), Expect = 8e-48
Identities = 103/233 (44%), Positives = 142/233 (60%), Gaps = 3/233 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ GA FVQE V E+L+ K+ VF ++ +V ++ I ++++++ IV
Sbjct: 96 ALDGAFFVQESVFEDLEAKQSVFHAVEELVSESVILSSSTSCLMPSNVFSQVQNRTRCIV 155
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
SHPVNPPYYV LVE+VP P T P V + +M ++GQ PV L +EIDGF LNR+QYAI+
Sbjct: 156 SHPVNPPYYVRLVELVPHPETLPAVMEVAYSLMTDVGQAPVRLRKEIDGFALNRVQYAII 215
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA-EGMQSYIDRYGETIYRV 215
E WRL VMSEGLGMRYAF+G +ET HLNA EGM+ Y+ RY E + RV
Sbjct: 216 AESWRLVQDGVISVKDIDLVMSEGLGMRYAFIGPIETMHLNAPEGMKDYLQRYSEGMKRV 275
Query: 214 SNEMGPAPRMTTNKSRNSVCEQLEKLVPIEK--LQDRRNWRDLCLMRLSLLKK 62
N GP P + + V +++ +++P E+ L RR RD LM L+ LK+
Sbjct: 276 LNTFGPVPDFSGEPAAR-VIKEICEMIPGEQEHLSARRERRDQLLMGLAKLKE 327
>UniRef50_A5A8P0 Cluster: Putative uncharacterized protein; n=3;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 284
Score = 182 bits (442), Expect = 1e-44
Identities = 88/232 (37%), Positives = 133/232 (57%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+K AI++QE E+L+ + + ++ +D + D TI ++GL +K + ++
Sbjct: 52 MKNAIYMQESALEDLNFRIQFYKVIDEIADPTTILASSTSTIPASKFTDGLINKERCLIV 111
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
HPVNPP ++PL E+VPAPWT + + EIM + Q+PV L +E+ GFV+NR+Q+A+L
Sbjct: 112 HPVNPPLFLPLTELVPAPWTSQDTVDRAAEIMRSVKQEPVKLKKEVLGFVVNRLQFALLA 171
Query: 388 EVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRVSN 209
E WRL VMS GLG RYAF G ET HLNA G++ Y RY I V
Sbjct: 172 ETWRLVADGVIGVNDVDAVMSAGLGPRYAFNGTCETVHLNAFGVRDYFKRYAAGITAVLK 231
Query: 208 EMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKEMN 53
+MGP P T K N + E+LE + ++ + R+ L+ ++ LKK++N
Sbjct: 232 DMGPIPDFTDEKVINKLEEELEPKMSTLNIRKHQAEREEKLVEIAKLKKDLN 283
>UniRef50_Q2CEL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacteraceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Oceanicola granulosus HTCC2516
Length = 312
Score = 161 bits (390), Expect = 2e-38
Identities = 85/231 (36%), Positives = 123/231 (53%), Gaps = 3/231 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+GAI VQE PE L++K+ VF LD D + + ++GL ++ +V
Sbjct: 78 AVRGAIHVQENTPETLEVKRSVFAQLDDAADADAVIASSSSALLPSAFTDGLAGAARCLV 137
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+HP+NPP+ VP VE+VP P T E +TR +M IGQ P+ +RE++GFV+NR+Q A+L
Sbjct: 138 AHPLNPPHLVPAVELVPGPQTSAETVARTRALMSSIGQSPIETSREVEGFVMNRLQGALL 197
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAE-GMQSYIDRYGETIYRV 215
DE + L M +GL R+ FLG ET LNA G+ ++DRYG +
Sbjct: 198 DEAFALVEQGLASPADIDTAMRDGLARRWTFLGPFETIDLNAPGGIGDFMDRYGPAYAAI 257
Query: 214 SNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKL--QDRRNWRDLCLMRLSLL 68
+ PR ++ E+L + + RR WRD CL RL+ L
Sbjct: 258 GTQRPTRPRWD-----GTLRERLVQYASGQSSTHDARRAWRDRCLARLARL 303
>UniRef50_Q98LG2 Cluster: Mll1034 protein; n=5;
Alphaproteobacteria|Rep: Mll1034 protein - Rhizobium
loti (Mesorhizobium loti)
Length = 315
Score = 159 bits (385), Expect = 9e-38
Identities = 85/239 (35%), Positives = 133/239 (55%), Gaps = 3/239 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ A VQE PENLD+K++VF +D + TI ++ L+ + + +V
Sbjct: 78 ALADAAHVQENTPENLDVKREVFSLIDRLAGPQTIIASSTSALLPSKFTDHLQGRHRCLV 137
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HP+NPPY +P E+VPAPWT E +KTR + + G P+ + RE+DGF++NR+Q A+L
Sbjct: 138 VHPINPPYLIPAAEVVPAPWTSAETLEKTRAFLIDAGHAPLVMRRELDGFIMNRLQGALL 197
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAE-GMQSYIDRYGETIYRV 215
+E +RL + +GL +R++F+G ET LNA G++ Y+DRY + IY
Sbjct: 198 EEAFRLVADGYASVEDVDIGIRDGLALRWSFMGPFETIDLNAPGGVRDYVDRY-QGIY-- 254
Query: 214 SNEMGPAPRMT--TNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKEMNKKY 44
SN R + +V + K +P L DR+ WRD LM L+ KK+ ++++
Sbjct: 255 SNIFPQMLRRVDWAGEVMATVEAERSKRLPRGSLGDRQVWRDRRLMALAAHKKKSDQEF 313
>UniRef50_A5G288 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Proteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Acidiphilium cryptum (strain JF-5)
Length = 312
Score = 155 bits (377), Expect = 8e-37
Identities = 80/230 (34%), Positives = 122/230 (53%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A ++QE V E ++ K+++F LD+VV T+ ++ + + + ++
Sbjct: 75 AVADAAYIQESVFETVEQKRQIFAALDAVVGPETLIGSSSSGIPASAFTDHVGCRERCLI 134
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+HPVNPPY +P+VE+VPAPWT ++ R +ME +GQ+PV LTREI+GF LNR+Q +L
Sbjct: 135 AHPVNPPYLIPVVELVPAPWTAAATVQRVRALMESVGQEPVELTREIEGFALNRLQGLLL 194
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRVS 212
E W+L +S GLG+R++F+G ET LNA G + R T+Y
Sbjct: 195 AEAWKLVADGIMSVEDVDRTVSAGLGLRWSFMGPFETIDLNAPGGVADYARRFRTMYETI 254
Query: 211 NEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKK 62
+ V Q +P ++L +R WRD LM L K+
Sbjct: 255 AGSRGVDLGWDDALIAEVERQRRVALPADQLAERSAWRDRRLMALMAHKR 304
>UniRef50_Q6SEY0 Cluster: 3-hydroxyacyl-CoA dehydrogenase domain
protein; n=1; uncultured bacterium 582|Rep:
3-hydroxyacyl-CoA dehydrogenase domain protein -
uncultured bacterium 582
Length = 322
Score = 151 bits (366), Expect = 2e-35
Identities = 82/233 (35%), Positives = 126/233 (54%), Gaps = 1/233 (0%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
TAV +VQEC PE L LK+++F LD++ TI S L + + +
Sbjct: 88 TAVCEVDYVQECGPEVLGLKQELFSELDALTPPETILASSTSGLMASQFSAHLAGRHRAL 147
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
V+HPVNPP+ VP+VEI P+ WT PE+ + ++M +GQ PV++ +EI GF+LNR+Q A+
Sbjct: 148 VAHPVNPPHLVPVVEISPSEWTDPEIVRVVVDVMTGVGQTPVTVQKEIPGFLLNRLQGAL 207
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAE-GMQSYIDRYGETIYR 218
L+E RL + +GLG+R++F+G ET LNA G+ Y RYG +YR
Sbjct: 208 LNEALRLAQGGFATVEDIDKTVRDGLGLRWSFMGPFETIDLNAPGGLADYAKRYG-PMYR 266
Query: 217 VSNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKE 59
+ AP ++ + + + I+ + R WRD L L+ K++
Sbjct: 267 DMAQDQAAPADWAEEAMTPLHDARRAELSIDAVASRHFWRDSRLAALAAHKQK 319
>UniRef50_Q0FUQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Alphaproteobacteria|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Roseovarius sp. HTCC2601
Length = 316
Score = 151 bits (366), Expect = 2e-35
Identities = 80/232 (34%), Positives = 125/232 (53%), Gaps = 1/232 (0%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV GA FV EC+ ENLD K+++F L+ + I + L + + I+
Sbjct: 79 AVAGADFVHECIVENLDSKRQIFAALNDAAEPEAILASTTSSFPVSHFASDLACRDRCII 138
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HP PP+ +P+ EI PAP+T EV+++T M E GQ PV + +E++GFVLNR+Q A+L
Sbjct: 139 VHPATPPHLLPVTEICPAPFTSAEVSERTTAFMRECGQIPVRIKKEVEGFVLNRMQAALL 198
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAE-GMQSYIDRYGETIYRV 215
E+ L ++SEG G+R+AFLG E LNA G++ Y++RYG
Sbjct: 199 VEMLTLLREDLIDARDIDAIISEGFGLRWAFLGPFEGVDLNAPGGIRQYLERYGFLARDR 258
Query: 214 SNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKE 59
E G + ++ +++ + +P+E L ++ WRD ++ L LK E
Sbjct: 259 GREYGLGD-VLPPETIDTLDDYARSRIPLEALPEKVAWRDESILALRALKAE 309
>UniRef50_A1FMQ0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Pseudomonas putida W619
Length = 320
Score = 144 bits (349), Expect = 2e-33
Identities = 78/232 (33%), Positives = 123/232 (53%), Gaps = 1/232 (0%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A++ + VQE V E ++ K +F +D++ + I ++ L + + +V
Sbjct: 87 ALRDVVLVQENVRETVEAKIDIFSRMDALAPKDAILASSTSWLPASEFTKDLPGRGRCVV 146
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+HP NPPY VPLVE+ PAPWT+ EV + EI GQ PV L+REI GF+LNR+Q A+L
Sbjct: 147 AHPTNPPYLVPLVELCPAPWTESEVMVRAHEIYTAAGQSPVVLSREIHGFLLNRVQAAVL 206
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA-EGMQSYIDRYGETIYRV 215
+E ++L V+ +GL +R++F+G ET LNA G+ Y RYG+
Sbjct: 207 NECFKLHEEGFASSEDIDRVLKDGLALRWSFMGPFETIDLNAPAGVSDYAKRYGQQNRET 266
Query: 214 SNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKE 59
N + +R V ++ + + +E + R WRD LM L+ K++
Sbjct: 267 INSENAFDWSESAVAR--VHDERRQKLELEGIALRSAWRDRRLMALAAHKRQ 316
>UniRef50_Q7WLK3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=3; Bordetella|Rep: Putative 3-hydroxyacyl-CoA
dehydrogenase - Bordetella bronchiseptica (Alcaligenes
bronchisepticus)
Length = 313
Score = 143 bits (346), Expect = 5e-33
Identities = 76/221 (34%), Positives = 122/221 (55%), Gaps = 2/221 (0%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A +VQE V ENL LK+ +F LD++ + + +E L +++ +V
Sbjct: 77 AVGRADYVQEAVSENLALKRTLFAELDALAPAHALLASSTSTYGASQFTEALAGRARCLV 136
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+HP+ PP+ P+VE+ + WT P+V M +GQ PV + +EI GFVLNR+Q A+L
Sbjct: 137 AHPMTPPHLSPVVEMAASAWTDPQVLAGAEAFMRSLGQHPVRIRKEIPGFVLNRLQGALL 196
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAE-GMQSYIDRYGETIYRV 215
E++R+ ++S+GLG+R+A LG LE LNA G+ Y+ RYG +
Sbjct: 197 MEMFRVIADDVISPADADALISQGLGLRWATLGPLEGVDLNAPGGIADYLQRYGHIFNDM 256
Query: 214 SNEMG-PAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRD 95
+ G PAP + +++ + +P+E+L+ +R WRD
Sbjct: 257 AVGQGLPAP--VDAELISALDGAMRAALPLERLEAKRGWRD 295
>UniRef50_A1B801 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Rhodobacteraceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Paracoccus denitrificans (strain Pd 1222)
Length = 311
Score = 142 bits (345), Expect = 6e-33
Identities = 79/220 (35%), Positives = 114/220 (51%), Gaps = 1/220 (0%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ GA VQE PE L +K+++F LD + I +EGL S+ +V
Sbjct: 77 ALDGAELVQESGPEVLAIKRELFARLDGLAAAGVILASSSSALMASAFAEGLPGASRCLV 136
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HPVNPP+ VP+VEI PAP+T P + + R+I GQ PV L REIDGF+LNR+Q +L
Sbjct: 137 GHPVNPPHLVPVVEIAPAPFTDPVITARARDIYARAGQVPVMLKREIDGFILNRLQAVVL 196
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAE-GMQSYIDRYGETIYRV 215
E RL + GLG R+AF+G +ET +LNA G Y+ RYG + +
Sbjct: 197 AESLRLIEQGYVDPQGLDDTIRHGLGRRWAFMGPMETINLNAPGGAGDYLARYGRMMAGL 256
Query: 214 SNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRD 95
+ + T ++ V + ++ R++WRD
Sbjct: 257 A-KTSARDEAFTAQAAAIVGSAFPDTATPQAIRARQDWRD 295
>UniRef50_Q11EZ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=3; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 318
Score = 139 bits (337), Expect = 6e-32
Identities = 74/235 (31%), Positives = 126/235 (53%), Gaps = 1/235 (0%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ GA VQEC PEN+DLK +F+ L + D+ + + ++ + +V+V
Sbjct: 86 ALDGADLVQECAPENIDLKVDLFRWLADLTPDHVVLASSSSALIASLIAPDIEIRRRVLV 145
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HP NPPY +P++E+VP+P T + + EI +PV + RE++GF+ NR+Q A+L
Sbjct: 146 GHPGNPPYLIPVIEVVPSPETAQAIIDRAFEIYRNSHLKPVLVRREVEGFIFNRLQGAVL 205
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAE-GMQSYIDRYGETIYRV 215
E + L VM GLG R++ +G ETA LN G+ S+ ++ G R+
Sbjct: 206 REAYCLVRDGIASVDDIDEVMRSGLGRRWSVIGPFETADLNTRGGIASHAEKMGPAYARM 265
Query: 214 SNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKEMNK 50
E G T + + V Q +++P+++ + R WRD L++ + L +++N+
Sbjct: 266 GAERGQNDPWTPDLV-DEVTRQRREIMPLDQWEARVRWRDEQLLK-AKLARDLNR 318
>UniRef50_Q160J3 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Roseobacter denitrificans OCh 114|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Roseobacter
denitrificans (strain ATCC 33942 / OCh 114)
(Erythrobactersp. (strain OCh 114)) (Roseobacter
denitrificans)
Length = 331
Score = 138 bits (334), Expect = 1e-31
Identities = 75/226 (33%), Positives = 115/226 (50%), Gaps = 1/226 (0%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A ++QE E LD+K ++ + +D + + SE +K + + +V
Sbjct: 93 AVSAADYIQESGSEALDVKIELTREIDRFAAPHVVIGSSTSGITASRYSETIKGRERCLV 152
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HP+NPP+ VPLVE+VPAPWT +++ IGQ P+ L REIDGFV+NR+Q A+L
Sbjct: 153 VHPINPPHLVPLVEVVPAPWTAQSAVDTVHDLLSAIGQVPILLNREIDGFVVNRLQGALL 212
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAE-GMQSYIDRYGETIYRV 215
E + L +S+GLG+R++ +G ET HLNA G+ Y+ R+G +YR
Sbjct: 213 REAFHLLDQGVASRKDIDKAISDGLGLRWSLMGPFETIHLNAPGGVSDYVRRFG-PMYRD 271
Query: 214 SNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRL 77
P P + L P+ + + RD L+R+
Sbjct: 272 MFADDPDPVDWETVVDAGLEADLTASQPLSGISAAQKTRDSALLRM 317
>UniRef50_A3VGB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Rhodobacterales bacterium HTCC2654
Length = 324
Score = 131 bits (316), Expect = 2e-29
Identities = 68/223 (30%), Positives = 114/223 (51%), Gaps = 4/223 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ GA VQE V E+L +K+ +F + + D+ + + H + +V
Sbjct: 78 ALSGAEVVQESVREDLAIKRALFDEIGAAAPDDCLLLSSTSALPGSQFLSDIPHPERALV 137
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HPVNPP ++PLVE+ P T PE ++ R E G +P+++ +EIDGF+LNR+QY ++
Sbjct: 138 GHPVNPPSHIPLVELCATPLTAPETVERARRFYTEAGMEPITVNKEIDGFILNRLQYTLV 197
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA-EGMQSYIDRYGETIYRV 215
E L VM+ GL +R+A +G TAHLNA EG ++ + + +
Sbjct: 198 AEAMHLVGEGYCSAADIDRVMTSGLALRWASIGPFMTAHLNAHEGFAGFVGQ----LEGM 253
Query: 214 SNEMGPAPRMTTNKSRNSVC---EQLEKLVPIEKLQDRRNWRD 95
+MG R + + V +++ + P+ + D ++WRD
Sbjct: 254 MKKMGADARTDYDWGPDLVAKINDEMTRRQPVGAIPDAQSWRD 296
>UniRef50_Q93QG7 Cluster: Hydroxyacyl-CoA dehydrogenase; n=1;
Brevibacterium sp. HCU|Rep: Hydroxyacyl-CoA
dehydrogenase - Brevibacterium sp. HCU
Length = 316
Score = 118 bits (284), Expect = 2e-25
Identities = 67/226 (29%), Positives = 111/226 (49%), Gaps = 1/226 (0%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
TA GAI VQE PE++ K+ +F++L +V D TI + + + +
Sbjct: 79 TAASGAILVQEAGPEDVQTKQHIFEDLTAVTSDETILASASSAIPSSRFVD-VHSAFRSL 137
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
+ HP NPPY + +VE+V P T+ + + ++ E+ G V + RE+DGFV NRIQ A+
Sbjct: 138 IGHPGNPPYLLRVVELVGNPSTEEQTILRAGQLYEQAGLSAVRVNREVDGFVFNRIQGAV 197
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAE-GMQSYIDRYGETIYR 218
L E + L ++ +GLG+R++ G T LN G+ ++ +R G +R
Sbjct: 198 LREAYALVGAEIIDPMDLDTLVQDGLGLRWSVAGPFATVDLNVRGGITAHAERMGSAYHR 257
Query: 217 VSNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMR 80
++ + + T C + K VP+E+ RD LM+
Sbjct: 258 MAGALDTSKEWTDTLVAKVNCSR-RKAVPLEQWDQAVADRDTQLMK 302
>UniRef50_UPI000050F939 Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 314
Score = 112 bits (269), Expect = 1e-23
Identities = 67/209 (32%), Positives = 103/209 (49%), Gaps = 4/209 (1%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHK--SQ 581
TAV GA FVQE PE+ K K+F + + + I + L + ++
Sbjct: 73 TAVAGASFVQESGPEDPQAKPKLFAQIAAAAPKDAIFATSSSTIPASLIARHLPPEVAAR 132
Query: 580 VIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQY 401
VIV HP NPP+ +PLVE+VPAP T + ++ E G++PV+L RE+ GFV NR+Q
Sbjct: 133 VIVGHPFNPPHLMPLVEVVPAPATSSDTVERALEFYRSCGREPVALNREVRGFVGNRLQN 192
Query: 400 AILDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA--EGMQSYIDRYGET 227
A++ E L VM LG+R++ +G E HL +G++ ++D G +
Sbjct: 193 ALMKEAISLVENGVISAPDLDSVMKNSLGLRWSAVGQFEAMHLGGGDKGIRGFMDHIGTS 252
Query: 226 IYRVSNEMGPAPRMTTNKSRNSVCEQLEK 140
E+G P + V Q+E+
Sbjct: 253 F----AEIGELPLDLSEAGMADVYAQVEQ 277
>UniRef50_Q5LTH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=16; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Silicibacter pomeroyi
Length = 487
Score = 111 bits (266), Expect = 2e-23
Identities = 58/192 (30%), Positives = 94/192 (48%), Gaps = 2/192 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV GA ++QE VPE LDLK KV++++ D I EG Q++V
Sbjct: 74 AVTGAAWIQESVPERLDLKLKVYRSIQEACDPGAILGSSTSGFKPSELQEGALRPGQIVV 133
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+HP NP Y +PL+E+V P PE+ ++ +EIM +GQ P+ + +EID + +R A+
Sbjct: 134 THPFNPVYLLPLIELVTTPENSPEMIERAKEIMRGLGQFPLHVRKEIDAHIADRFLEAVW 193
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL--NAEGMQSYIDRYGETIYR 218
E L + G G+R+A +G ET + GM+ ++ ++G +
Sbjct: 194 REALWLVKDGIATTEEIDEAIRMGFGIRWAQMGLFETYRVAGGEAGMKHFMAQFGPCLSW 253
Query: 217 VSNEMGPAPRMT 182
++ P T
Sbjct: 254 PWTKLMDVPEFT 265
>UniRef50_A4R503 Cluster: Putative uncharacterized protein; n=3;
Sordariomycetes|Rep: Putative uncharacterized protein -
Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 330
Score = 109 bits (262), Expect = 7e-23
Identities = 59/164 (35%), Positives = 87/164 (53%), Gaps = 3/164 (1%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLK--HKSQ 581
TA+K A FVQE PE LD K+K+F+ + ++VD +TI +GL+ HK +
Sbjct: 78 TALKNASFVQENGPERLDFKQKLFRGVANLVDPDTIIATSSSGLTCSSIQQGLEAQHKPE 137
Query: 580 -VIVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQ 404
V+V HP NPP+ +PLVE+V T +T EE+G++ V + +E+ G V NR+Q
Sbjct: 138 RVVVGHPFNPPHLIPLVEVVGGEQTSQATISRTMGFYEEVGKKAVHIKKEVVGHVANRLQ 197
Query: 403 YAILDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
A++ EV L MS G G+R+ +G HL
Sbjct: 198 AALMREVMYLVQEGVADVSDIDRAMSNGPGLRWGVMGPSMLFHL 241
>UniRef50_A3M445 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Acinetobacter baumannii ATCC 17978|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Acinetobacter
baumannii (strain ATCC 17978 / NCDC KC 755)
Length = 233
Score = 106 bits (255), Expect = 5e-22
Identities = 62/227 (27%), Positives = 107/227 (47%), Gaps = 1/227 (0%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNP 554
F+QE PE LDLK+ ++Q + S + T+ + H ++ + HP NP
Sbjct: 6 FIQENAPERLDLKQNLYQEITSYCPEKTLIASSSSGLKVSDFQKDATHPERIFLGHPFNP 65
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
P+ +PLVEIV T P++ KK E + +G+ P+ L +E+ G V NR+Q A+ E + L
Sbjct: 66 PHLLPLVEIVGGKLTDPQILKKASEFYQSLGKHPIVLNKEVKGHVANRLQAALWREAFSL 125
Query: 373 XXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL-NAEGMQSYIDRYGETIYRVSNEMGP 197
++ G G+R+A G L N +G + I G + N+M
Sbjct: 126 VKEGVCSAEDVDIAITSGPGLRWALFGPYINMELANQKGFKEAIHHLGPPMTEWWNDMQN 185
Query: 196 APRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKEM 56
+ ++ + EQ ++L+ K D RD L+ + L++++
Sbjct: 186 FQH--SEETTELLEEQTKELLTHYKDIDLSQKRDKGLVDILKLRQQL 230
>UniRef50_A0GEI2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Burkholderia|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Burkholderia phytofirmans
PsJN
Length = 317
Score = 105 bits (253), Expect = 9e-22
Identities = 56/166 (33%), Positives = 89/166 (53%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A FV E +PE L+LK +++ L ++ D+ I + L+ K + +++H
Sbjct: 96 AQFVIEAIPEVLELKHRLYAALTQLLADDAILASNTSGFHPDQLAAPLRAKDRFVIAHFW 155
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
NPP+ +PLVE+VP T PEV ++T +M IG +PV L + I GFV NR+Q+A+L E
Sbjct: 156 NPPHMIPLVEVVPGTATAPEVTQQTAALMSAIGMEPVVLAKAIPGFVGNRLQFAMLREAL 215
Query: 379 RLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYID 242
+ VM LG R+ +G LE A + G+ +++D
Sbjct: 216 HIVRSGAATPDVVDRVMKASLGRRWGIVGPLEGADMG--GLDTFLD 259
>UniRef50_O29062 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 315
Score = 105 bits (253), Expect = 9e-22
Identities = 55/180 (30%), Positives = 88/180 (48%), Gaps = 2/180 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGL-KHKSQVI 575
A+KGA +VQE E L++K+ +F+ +D++ + TI KH + I
Sbjct: 79 ALKGAYYVQESAVEKLEVKRDLFEKMDAIAEPETILATSTSGLSISEIQTAARKHPERCI 138
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
+HP NPP+ +PLVE+VP T +KT E ME +G++P+ + +++ G V NR+ A+
Sbjct: 139 TAHPYNPPHLIPLVEVVPRKQTDESCTEKTVEFMERMGKKPIVVKKDVPGMVANRLAAAL 198
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL-NAEGMQSYIDRYGETIYR 218
E L + G G+R+A G T HL +G Y + + YR
Sbjct: 199 WREAVNLVYQGIATPEEIDVAVKYGPGIRWAITGVYLTYHLGGGQGGMKYFLEFFDDHYR 258
>UniRef50_UPI00005102FD Cluster: COG1250: 3-hydroxyacyl-CoA
dehydrogenase; n=1; Brevibacterium linens BL2|Rep:
COG1250: 3-hydroxyacyl-CoA dehydrogenase -
Brevibacterium linens BL2
Length = 311
Score = 104 bits (249), Expect = 3e-21
Identities = 72/236 (30%), Positives = 110/236 (46%), Gaps = 5/236 (2%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXX-XXXXSEGLKHKSQVI 575
+V A FVQE PE LD+K+ + DS V + I ++ H +++
Sbjct: 75 SVGDADFVQENGPERLDIKQSMLAETDSAVPASAIIASSTSGFAPSELATKATNHPERIV 134
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
V HP NP + VPLVE+VP P T EV K+ EI IG++P+ + E+ G V NR+Q A+
Sbjct: 135 VGHPFNPAHLVPLVELVPTPATPAEVVKRGLEIYRSIGKKPILVRAELPGHVTNRLQAAL 194
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA--EGMQSYIDRYGETIY 221
E + L +S G G+R+A LG L L+ GM+ ++ G
Sbjct: 195 WQEAYSLVDRGMVSVEDIDTAISYGPGLRWAILGPLVQQGLSGGQGGMRHVLEHLGPPQE 254
Query: 220 RVSNEMGPA--PRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKE 59
++G T+K V ++LE P+ + RD L+ L LK++
Sbjct: 255 VWMRDLGQVHLGEELTDKLVAGVDDELEGKDPVLIAKQ----RDEMLLELIALKRK 306
>UniRef50_Q1GEJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=17; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Silicibacter sp. (strain
TM1040)
Length = 491
Score = 103 bits (248), Expect = 4e-21
Identities = 55/177 (31%), Positives = 88/177 (49%), Gaps = 2/177 (1%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
V+G +VQE VPE LDLK+KV+ L++ + +G + +Q++V+
Sbjct: 76 VQGVDWVQESVPERLDLKQKVYAELEAHAPGGAVIGSSTSGYKPSQLQDGFTNAAQIVVA 135
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
HP NP Y +PLVE+V PE+ K + I+ EIG P+ L +EID V +R A+
Sbjct: 136 HPFNPVYLMPLVEVVTTDVNTPEMIAKAKAIITEIGMYPLHLKKEIDAHVADRFLEAVWR 195
Query: 388 EVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL--NAEGMQSYIDRYGETI 224
E L + G G+R+A +G ET + GM+ ++ ++G +
Sbjct: 196 EALWLVKDGIATTEEIDNAIRYGFGIRWAQMGLFETYRVAGGEAGMKHFMAQFGPAL 252
>UniRef50_Q4J0Z7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal:3-hydroxyacyl-CoA dehydrogenase, NAD binding
domain; n=2; Gammaproteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, C-terminal:3-hydroxyacyl-CoA
dehydrogenase, NAD binding domain - Azotobacter
vinelandii AvOP
Length = 307
Score = 103 bits (246), Expect = 6e-21
Identities = 52/169 (30%), Positives = 90/169 (53%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
V A + E +PE L+LK+ ++ L+++V T+ +EG++H +++++
Sbjct: 80 VADARLLIEAIPERLELKRALYAELEALVGTGTVIASNTSGLPPDALAEGMRHPERLLIA 139
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H NPP+ +PLVEIVP T+ E + R ++ + + V L + I GF+ NR+Q+A+L
Sbjct: 140 HFWNPPHLIPLVEIVPGSATRAEHLEAVRTLLAGMELEAVVLDKAIPGFIGNRLQFAVLR 199
Query: 388 EVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYID 242
E + VM LG RYA +G LE A + G+ +++D
Sbjct: 200 EALHIVRSGAASAETVDRVMRASLGRRYAMVGPLEAADMG--GLDTFLD 246
>UniRef50_Q73Q34 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=1; Treponema denticola|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Treponema denticola
Length = 309
Score = 100 bits (239), Expect = 4e-20
Identities = 61/211 (28%), Positives = 102/211 (48%), Gaps = 5/211 (2%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V E +PEN+DLK + F L+ + +TI ++ +K + +VI +H
Sbjct: 87 AAIVIEALPENMDLKTETFGKLEKICPQDTILATASGHSVSEVIAQ-VKKRDRVIATHFW 145
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
PP +PLVE+ AP T T E+++ IG++PV + +EIDGF+ NRIQ+A L E W
Sbjct: 146 FPPQLLPLVEVCGAPETSKATIDTTCELLKGIGKKPVVIDKEIDGFIGNRIQFAALREAW 205
Query: 379 RLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRVSNEMG 200
L ++ +G RY+ G +E+A + G+ ++ +SN+
Sbjct: 206 ALYDSGVATADAIDSIVRYSIGRRYSVTGPIESA--DVAGLPVMVNFAAYLQPSLSNDKD 263
Query: 199 PAPRM-----TTNKSRNSVCEQLEKLVPIEK 122
P ++ K N +++KL+ K
Sbjct: 264 PPAKLFDLAKVDGKVYNRSKAEIDKLIAARK 294
>UniRef50_A5D5N2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Pelotomaculum thermopropionicum SI|Rep:
3-hydroxyacyl-CoA dehydrogenase - Pelotomaculum
thermopropionicum SI
Length = 319
Score = 99 bits (238), Expect = 6e-20
Identities = 59/177 (33%), Positives = 89/177 (50%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
V GA V E VPE LDLKK++F LD + + I + +V+ +
Sbjct: 83 VTGADMVIEAVPEKLDLKKEIFAQLDKLCPPSVILATNTSGLPITAIASAAARPERVLGT 142
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H P Y +PLVE+V + +T P+VA T ++ IG++PV + ++I GF+ NR+Q+AI
Sbjct: 143 HFYMPAYLIPLVEVVCSDYTSPDVAGDTVAFLQSIGRKPVLVKKDIPGFIGNRLQHAIAR 202
Query: 388 EVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYR 218
E L V LG+R+A G LE LN G+ ++D E +Y+
Sbjct: 203 EAISLLQKGIASAQDIDTVARYTLGLRFAHTGPLEQRDLN--GLDVHLD-VAEYLYQ 256
>UniRef50_Q0UZL9 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 308
Score = 99 bits (238), Expect = 6e-20
Identities = 48/186 (25%), Positives = 95/186 (51%), Gaps = 2/186 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV + +QE PENLD+K+K+++ ++ ++ + ++ ++ K++++V
Sbjct: 75 AVSDSHIIQESGPENLDVKRKLWKEVEKYAPNDALLWSSTSGIPASQQAQDMQDKTRLLV 134
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HP NPP+ +PL+E+VP+ T V +T++ E G+ P+ + RE GFV NR+ +A+L
Sbjct: 135 VHPYNPPHIMPLLELVPSSETSDTVISRTQDFWRERGRVPIHIKRETTGFVANRLAFALL 194
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA--EGMQSYIDRYGETIYR 218
E L ++ +G R++ G ++ H G++ + G T+
Sbjct: 195 RESIHLVNEGVVSVSELDQIVESSMGPRWSVAGPFKSYHAGGGPAGLEGFFKNIGGTVQS 254
Query: 217 VSNEMG 200
++ G
Sbjct: 255 CWDDAG 260
>UniRef50_Q9UX37 Cluster: 3-hydroxyacyl-CoA-dehydrogenase; n=4;
Sulfolobaceae|Rep: 3-hydroxyacyl-CoA-dehydrogenase -
Sulfolobus solfataricus
Length = 324
Score = 96.7 bits (230), Expect = 5e-19
Identities = 65/225 (28%), Positives = 104/225 (46%), Gaps = 6/225 (2%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGL-KHKSQVI 575
A+ FV E + E+ KK +F+ LD+ + + I + + +H + +
Sbjct: 84 AIHNVDFVIEAIIEDYTAKKNLFKLLDTQLPQDIIIASSTSGLLMTEIQKAMIRHPERGV 143
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
++HP NPP+ +PLVEIVP T E TRE ME++ + V L +E+ GF+ NR+ +A+
Sbjct: 144 IAHPWNPPHLLPLVEIVPGEKTSKETVDLTREFMEKLDRVVVLLRKEVPGFIGNRLAFAL 203
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL-NAEGMQSYIDRYGETIYR 218
E L VM+ +G+R+AF+G T HL EG Y G Y
Sbjct: 204 FREAVNLVDEGVATVEDIDKVMTAAIGLRWAFMGPFLTYHLGGGEGGIEYFFSKGFG-YG 262
Query: 217 VSNEMGPAPRMT--TNKSRNSVCEQLE--KLVPIEKLQDRRNWRD 95
+ M + + V EQ++ + + + QD WRD
Sbjct: 263 ANEWMHTLAKWDKFPYTAVKKVLEQMKEYEFIKGKSFQDLSRWRD 307
>UniRef50_Q39HR3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=24;
Burkholderia|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 305
Score = 95.9 bits (228), Expect = 1e-18
Identities = 59/228 (25%), Positives = 108/228 (47%), Gaps = 3/228 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNT-IXXXXXXXXXXXXXSEGLKHKSQVI 575
A+ G FVQE PE LDLK+ +++ +D V+ + I + KH + +
Sbjct: 70 ALDGVDFVQENGPERLDLKRALYRQMDDVLPAHVPIASSSSGLKMSDIQTACDKHPERCL 129
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
++HP NPP+ +PLVE+V T +V + ++ + +G+Q + L +E+ G V NR+ A+
Sbjct: 130 IAHPFNPPHLIPLVELVGGDATSQDVTARVKDFYDALGKQTIVLNKEMTGHVANRLAAAL 189
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL--NAEGMQSYIDRYGETIY 221
EV+ L ++ G G+R+ +G T HL G+ +++ I
Sbjct: 190 FREVYHLVGEGVVSVADADKAVAWGPGLRWGLMGQCLTYHLGGGTGGIAHFLEHLSGPIT 249
Query: 220 RVSNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRL 77
+++G P + R + ++L + +Q+ RD L+ L
Sbjct: 250 SWWDDLG-TPSFDPDVDR-KLNDELRAIQGERSMQELAAERDRLLVEL 295
>UniRef50_A5N111 Cluster: Hbd2; n=5; Clostridiales|Rep: Hbd2 -
Clostridium kluyveri DSM 555
Length = 319
Score = 95.9 bits (228), Expect = 1e-18
Identities = 67/239 (28%), Positives = 110/239 (46%), Gaps = 4/239 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+G FV EC+ E+L+LK++VF LD + I + KH +V++
Sbjct: 80 AVEGVDFVIECIAEDLELKQEVFSKLDEICAPEVILASNTSGLSPTDIAINTKHPERVVI 139
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+H NPP ++PLVE+VP T + T + +E IG++ V + +E GF+ NR+Q A+L
Sbjct: 140 AHFWNPPQFIPLVEVVPGKHTDSKTVDITMDWIEHIGKKGVKMRKECLGFIGNRLQLALL 199
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRVS 212
E + + G G R G + +A L + + I Y +
Sbjct: 200 REALYIVEQGFATAEEVDKAIEYGHGRRLPVTGPICSADLGGLDIFNNISSY--LFKDLC 257
Query: 211 NEMGPAPRMTTNKSRNSVCEQLEK----LVPIEKLQDRRNWRDLCLMRLSLLKKEMNKK 47
N+ P+ + + ++ + K P E LQ ++N R LM L+K+ N K
Sbjct: 258 NDTEPSKLLKSKVDGGNLGSKTGKGFYNWTP-EFLQKKQNERIQLLM--DFLEKDKNDK 313
>UniRef50_UPI000023E2B1 Cluster: hypothetical protein FG00090.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG00090.1 - Gibberella zeae PH-1
Length = 320
Score = 95.1 bits (226), Expect = 2e-18
Identities = 48/159 (30%), Positives = 78/159 (49%), Gaps = 1/159 (0%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNT-IXXXXXXXXXXXXXSEGLKHKSQVIVSHPVN 557
FVQE PE ++ K+ + + LD I + K S++++ HP N
Sbjct: 83 FVQENGPERVEFKQSLMEKLDENTRPGVAIASSSSGLPSSAFIQKCKKDPSRILIGHPFN 142
Query: 556 PPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 377
PP+ +PLVE+VP P T +V + +G++P+ L +E+ GFV NR+Q AI +E +
Sbjct: 143 PPHLIPLVEVVPHPGTSSDVVSSALAFYKSLGKKPILLHQEVPGFVSNRLQAAINNEAYS 202
Query: 376 LXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEG 260
L +++G G+R+A G + T L G
Sbjct: 203 LISRGIVSAKDLDMAVTQGPGLRWALTGPIATNALGGGG 241
>UniRef50_A6C4K6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Planctomyces maris DSM 8797|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Planctomyces maris DSM 8797
Length = 311
Score = 93.5 bits (222), Expect = 5e-18
Identities = 48/169 (28%), Positives = 79/169 (46%), Gaps = 2/169 (1%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNP 554
+VQE V E+ ++K V+Q + + I ++H + +++HP NP
Sbjct: 84 YVQESVIEDYEIKADVYQQFEQYAPEAAILGSSSSGLLMTRMQTVMQHPGRALIAHPFNP 143
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
P+ +PLVE+VP T E + +E + +G+ PV L RE+ G + NR+ A+ E L
Sbjct: 144 PHLIPLVELVPGEQTATETMETVKEFFQGLGKHPVILNREVPGHIANRLAAAVWRESLSL 203
Query: 373 XXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL--NAEGMQSYIDRYG 233
+ +G G+R+A +G L A G Q +ID G
Sbjct: 204 LDAGVASVEDIDAALCKGPGLRWALMGQHLIYELGGGAGGYQKFIDTIG 252
>UniRef50_A1FNB9 Cluster: 3-hydroxyacyl-CoA dehydrogenase precursor;
n=4; Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase
precursor - Pseudomonas putida W619
Length = 313
Score = 92.7 bits (220), Expect = 9e-18
Identities = 51/162 (31%), Positives = 84/162 (51%), Gaps = 2/162 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSE--GLKHKSQV 578
AV A V E VPE L+LK+K+F ++ +T+ E G + ++++
Sbjct: 74 AVSNADIVIEAVPERLELKQKLFADIAGFAPPHTVLASNTSVIPITEIGEMLGSEARARL 133
Query: 577 IVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYA 398
+ +H NPP+ VPLVE+V T V + T E+++ +G+ PV + R++ GF+ NR+Q+A
Sbjct: 134 VGTHWWNPPHLVPLVEVVRTEHTSLSVFESTFELLQSLGKSPVKVNRDVAGFIGNRLQHA 193
Query: 397 ILDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
+ E L V+ + GMR +LG +E A L
Sbjct: 194 MWREAISLVSQGVCDAETIDTVVKQSFGMRLPYLGPMENADL 235
>UniRef50_A4FKS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Saccharopolyspora erythraea
(strain NRRL 23338)
Length = 303
Score = 92.3 bits (219), Expect = 1e-17
Identities = 53/162 (32%), Positives = 76/162 (46%), Gaps = 2/162 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHK--SQV 578
AV A VQE PE L+ K+ +F ++ + +E L ++
Sbjct: 66 AVSDADLVQENGPERLEFKQDLFADIARHAPPRAVLASSSSGIVASAIAEHLPDDVAGRL 125
Query: 577 IVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYA 398
+++HP NPP VPLVEIVP T+ V + +G+ PV L +E+ GFV NR+Q A
Sbjct: 126 LIAHPFNPPQVVPLVEIVPGERTEERVTEAATAFYTALGKTPVRLRKEVPGFVANRLQSA 185
Query: 397 ILDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
++ E L VM LG RYA +G E+ HL
Sbjct: 186 VMREATHLVLEGVVRADELDTVMKSSLGGRYAAVGPFESFHL 227
>UniRef50_A2QCM7 Cluster: Catalytic activity: precursor; n=5;
Trichocomaceae|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 338
Score = 92.3 bits (219), Expect = 1e-17
Identities = 59/189 (31%), Positives = 92/189 (48%), Gaps = 4/189 (2%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
+A A VQE PEN+D K+ + +++V + ++ K++++
Sbjct: 95 SACASATIVQEQGPENVDWKQSAWARIEAVAPPSAHLWTSTSGIAASIQQAKMQDKTRLL 154
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIG--QQPVSLTREIDGFVLNRIQY 401
V HP NPP +PL+EIVPAP T E + RE G +PV + +EI GFV NR+ +
Sbjct: 155 VVHPFNPPNIMPLLEIVPAPGTSAERVEFAREYFSLPGSRHRPVVIQKEIPGFVGNRLAF 214
Query: 400 AILDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALET-AHLNAE-GMQSYIDRYGET 227
A+L E L ++ LG R+A G E+ H E G+ S++D+ G T
Sbjct: 215 ALLREACYLVQEDVVNAKDLDTILMASLGPRWAGNGVFESYQHGGGEGGIGSFLDKLGGT 274
Query: 226 IYRVSNEMG 200
+ V + G
Sbjct: 275 MQTVWDGQG 283
>UniRef50_Q5LPZ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=5; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Silicibacter pomeroyi
Length = 317
Score = 91.9 bits (218), Expect = 2e-17
Identities = 50/178 (28%), Positives = 78/178 (43%), Gaps = 2/178 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV GA F+QE PENL +K+ ++ L +V +N + + + ++
Sbjct: 82 AVAGAGFIQESAPENLAMKQALYHRLGRIVPENVVIGSSTSGLMMTDIQANCETPGRTVI 141
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HP NPPY +PLVEIV T P + E G+ P+ + +EI GFV R+Q A+
Sbjct: 142 GHPFNPPYLLPLVEIVGGERTDPAAVEWAGEFYRVAGKAPLMMKKEIPGFVATRLQEALW 201
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL--NAEGMQSYIDRYGETI 224
E + + G R G H+ A GM + +D++G +
Sbjct: 202 REALHMVANGEATPEDIDIALMNGPAPRMVSQGQCMAFHVACGAGGMATNLDQFGPAL 259
>UniRef50_Q2J5F5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=3; Actinomycetales|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Frankia sp. (strain CcI3)
Length = 323
Score = 91.5 bits (217), Expect = 2e-17
Identities = 51/175 (29%), Positives = 81/175 (46%), Gaps = 2/175 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV VQE PENL++K+ +F L+ T+ + + S +IV
Sbjct: 82 AVADVAVVQENTPENLEIKQDLFARLEKHAAAGTLLLSSTSTMLPADLGARMDNPSHLIV 141
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HP NPP+ +PLVE+V + P+ E +G+ PV L R I F NR+Q A+L
Sbjct: 142 GHPFNPPHVIPLVEVVGDTTSDPDAVSAAAEFYRSVGKTPVVLRRPIAAFAANRLQSALL 201
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA--EGMQSYIDRYG 233
E L +++ LG R+A +G ++ HL G+++++ G
Sbjct: 202 QESIHLVREGVVTVAELDDIVTGSLGPRWATVGPFQSFHLGGGPGGLRNWLGTLG 256
>UniRef50_Q2UUZ5 Cluster: RIB40 genomic DNA, SC009; n=4;
Trichocomaceae|Rep: RIB40 genomic DNA, SC009 -
Aspergillus oryzae
Length = 337
Score = 91.1 bits (216), Expect = 3e-17
Identities = 57/222 (25%), Positives = 96/222 (43%), Gaps = 3/222 (1%)
Frame = -2
Query: 715 PENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQ-VIVSHPVNPPYYVP 539
PE L+ K+ +F LD I + +H + V+V HP NPP+ +P
Sbjct: 111 PERLEFKRTLFAYLDEKARPEVIIASSSSGIPSSEYASACRHHPERVLVGHPFNPPHLIP 170
Query: 538 LVEIVPAPWTKPE-VAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXXX 362
LVE+VP T E V + E +G++PV + +EI GF+ NR+Q A+ E + L
Sbjct: 171 LVEVVPHRTTDRETVVPRAMEFYRSLGKKPVLIQKEIPGFIANRLQAALSMEAYSLVSRG 230
Query: 361 XXXXXXXXXVMSEGLGMRYAFLGALE-TAHLNAEGMQSYIDRYGETIYRVSNEMGPAPRM 185
++ LG+R+A G A Q +++ G ++M
Sbjct: 231 IISAADLDTTVTSSLGLRWALNGPYALNAMAGGGSFQHFLEHLGPAAKSWHDDMHKHTFS 290
Query: 184 TTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLLKKE 59
T ++ + +E +V L + RD L++L +K +
Sbjct: 291 MTPEAIQDLSRTVEPMVQATDLNTLQKERDDVLLKLMDMKSK 332
>UniRef50_Q988C8 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Mesorhizobium loti|Rep: 3-hydroxybutyryl-coA
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 309
Score = 89.8 bits (213), Expect = 6e-17
Identities = 47/168 (27%), Positives = 83/168 (49%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV GA V E VPEN+ +K V++ +D ++ +TI + + +++
Sbjct: 76 AVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVASDTSGIPITKLQAHISYPERMVG 135
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NPP+ +P++E++ T P+ R+++ IG PV + +++ GFV NR+ YA+L
Sbjct: 136 MHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIGLLPVVVKKDVPGFVENRVLYALL 195
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSY 248
E L +S G+G + A +G + A L+ G+ Y
Sbjct: 196 REAVDLVERGVIDPEDLDTCVSWGIGYKIAVIGPM--ALLDMAGLDIY 241
>UniRef50_Q8G825 Cluster: Possible butyryl-CoA dehydrogenase; n=2;
Bifidobacterium longum|Rep: Possible butyryl-CoA
dehydrogenase - Bifidobacterium longum
Length = 319
Score = 89.8 bits (213), Expect = 6e-17
Identities = 53/181 (29%), Positives = 86/181 (47%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNP 554
FV E V ENLD+KK V+ ++ + I + H + +V+H NP
Sbjct: 92 FVIESVAENLDVKKSVWTEVEHAAPKDAILSTNTSGLSPTALQSVMGHPERFVVAHFWNP 151
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
+PLVE+VP T P+V T ++M +IG++P + +E GFV NR+Q A+L E + +
Sbjct: 152 AQLMPLVEVVPGEKTDPKVVDITFDLMAKIGKKPAKIKKESLGFVGNRLQLAVLREAFYI 211
Query: 373 XXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRVSNEMGPA 194
VM LG R+ +G + A ++ G+ + + + N GP+
Sbjct: 212 VQQGIADAATVDDVMKYSLGRRWNLVGPI--ASIDLGGLDVFYNISTYLFDDMDNGTGPS 269
Query: 193 P 191
P
Sbjct: 270 P 270
>UniRef50_A3STE1 Cluster: Putative hydroxlacyl-CoA dehydrogenase;
n=3; Rhodobacteraceae|Rep: Putative hydroxlacyl-CoA
dehydrogenase - Sulfitobacter sp. NAS-14.1
Length = 309
Score = 89.4 bits (212), Expect = 8e-17
Identities = 63/238 (26%), Positives = 107/238 (44%), Gaps = 6/238 (2%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A++ + +QE PEN+ LK +++ ++S+V + I G++H ++I
Sbjct: 76 ALQDVVLIQENAPENVPLKHQLYAQIESIVAPDVIIASSTSAHPWSDLVPGMQHPDRLIT 135
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+HP NPP+ VPLVE+ P T V +G PV L ++ G + NR+ A+
Sbjct: 136 AHPFNPPHLVPLVEVY-GPDT--NVLDWAEGFYRSLGSVPVRLKKDAVGHIANRLSSALW 192
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL--NAEGMQSYIDRYGETIYR 218
E + + G G+R++ LGA HL A GM Y+ G + +
Sbjct: 193 REAVHIVAEGIADVDAVDQALVNGPGLRWSVLGAHMAYHLGGGAGGMAGYLAHLGPSQQK 252
Query: 217 VSNEMGPAPRMTTNKSRNSVCEQLEKLVPIE----KLQDRRNWRDLCLMRLSLLKKEM 56
+ +G APR+ + C +L V IE + RD L+ L+ ++K +
Sbjct: 253 RWDNLG-APRLDAD-----TCARLVDGVNIETAGRSIAQLEAERDAALIELAQMRKRL 304
>UniRef50_Q5HKI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=3; Staphylococcus|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Staphylococcus
epidermidis (strain ATCC 35984 / RP62A)
Length = 321
Score = 88.6 bits (210), Expect = 1e-16
Identities = 53/192 (27%), Positives = 84/192 (43%), Gaps = 2/192 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AVK A +QE VPE ++K V + +D L H +++V
Sbjct: 73 AVKDADHIQENVPEVEEIKDAVLKEIDFYAKPEATIGSSTSGIMPSELQANLSHPERLVV 132
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+HP +P Y +PLVEIVP T E K +I E IG + + EI+G + +R+ A+
Sbjct: 133 AHPFHPVYILPLVEIVPGKQTSEETTVKAEQIYESIGMDVLHVRHEIEGHIADRLMEALW 192
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL--NAEGMQSYIDRYGETIYR 218
E + + G+RYA G T HL GM+ + ++G + +
Sbjct: 193 RESLHIVNDGIATTEEVDKAFTHAAGLRYAQYGPFMTFHLAGGEGGMRHMLKQFGPALKK 252
Query: 217 VSNEMGPAPRMT 182
++ AP +T
Sbjct: 253 PWTKL-IAPELT 263
>UniRef50_Q39LC4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Burkholderia sp. 383|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 333
Score = 88.6 bits (210), Expect = 1e-16
Identities = 48/186 (25%), Positives = 90/186 (48%), Gaps = 2/186 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A FVQE VPE +++K +++ ++ +D I G K+ + I+
Sbjct: 84 AVARAQFVQESVPERIEIKHALYRRIEDHLDPRAIVCSSASGLLVKEMQAGWKNPGRFIL 143
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HP NPP+ +PLVE++ T+P V + + G+ + + +E+ G V NR+Q A+
Sbjct: 144 GHPFNPPHLIPLVELLGNEKTEPGVLELAEQFYAACGKITIRVNKEVPGHVANRLQAALW 203
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA--EGMQSYIDRYGETIYR 218
E L +S G G+R++ +G +L + G+ + +R+ + +R
Sbjct: 204 REAIHLVVEGVATVGDVDKAVSAGPGLRWSVMGPHMLFNLGSGGHGLGVFCERFAPSFHR 263
Query: 217 VSNEMG 200
+++G
Sbjct: 264 WWDDLG 269
>UniRef50_Q396V2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 317
Score = 87.4 bits (207), Expect = 3e-16
Identities = 50/175 (28%), Positives = 79/175 (45%), Gaps = 1/175 (0%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLK-HKSQVI 575
AV GA VQE PE +D K+ ++ LD+++ + G H + +
Sbjct: 78 AVAGAGLVQENGPERIDFKRTLYGQLDALLPPDVPIASSSSGLTMSEIQTGCPAHPERCV 137
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
+ HP NPP+ +PLVEIV T + +K +G++ + L +E+ G V NR+Q A+
Sbjct: 138 IGHPFNPPHLIPLVEIVSGAQTSEQTVEKVTAFYTSLGKRTIRLHKEVPGHVANRLQAAL 197
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGE 230
EV L + G G+R+ +G HL G Q I+ + E
Sbjct: 198 WREVVHLVSTGVVSVADADAAVCWGPGLRWGLMGPTLLFHLG--GGQGGIEHFFE 250
>UniRef50_A3YAS5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Marinomonas sp. MED121|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Marinomonas sp. MED121
Length = 323
Score = 87.0 bits (206), Expect = 4e-16
Identities = 59/223 (26%), Positives = 97/223 (43%), Gaps = 5/223 (2%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHK-SQVIVSHPVNP 554
+QE PE LD K+ +F +LD +V + + + L+ + + +V HP NP
Sbjct: 90 IQESTPERLDAKRSLFADLDCIVPADVVIISSTSGFAMTDMANELETQPDRFVVGHPFNP 149
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
PY VP E+ T EV T E +Q + +E+ GF+ NR+Q A+ E +
Sbjct: 150 PYLVPFCEVCGGERTSQEVVDWTAAFYEATEKQVAKMDKELPGFIGNRLQEALWREALHM 209
Query: 373 XXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA--EGMQSYIDRYGETIYRVSNEMG 200
++ G G+R+A +G T HL GM +D + + + +
Sbjct: 210 VANKECSVEDIDKAIAYGPGLRWAIMGHCLTFHLGGGQGGMAHLLDHFEDALEEPWTRL- 268
Query: 199 PAPRMTTNKSRNSV--CEQLEKLVPIEKLQDRRNWRDLCLMRL 77
AP++T + V C I++L RD CL+R+
Sbjct: 269 KAPKLTQELKDDMVAGCLTQANGASIDELVQE---RDDCLIRI 308
>UniRef50_Q97UK9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Sulfolobus|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Sulfolobus solfataricus
Length = 384
Score = 87.0 bits (206), Expect = 4e-16
Identities = 45/124 (36%), Positives = 69/124 (55%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
++ A FV E VPE ++LK+KVF+ LDS+ +T +E K K ++I
Sbjct: 79 MRDADFVIEAVPEIIELKRKVFETLDSITPSHTFLASNTSSIPISTIAEVTKRKEKIIGM 138
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H NPP + LVEIVP+ +T E + T ++ +++ + PV L E+ GFV NRI ++
Sbjct: 139 HFFNPPPIMKLVEIVPSKYTSDETIEVTIDLAKKMNKIPVKLKVEVPGFVSNRIFLRLMQ 198
Query: 388 EVWR 377
E R
Sbjct: 199 EACR 202
>UniRef50_A5V325 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 322
Score = 85.8 bits (203), Expect = 1e-15
Identities = 56/230 (24%), Positives = 97/230 (42%), Gaps = 2/230 (0%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+G FVQE PE D+K+ +F LD +V + + GL ++ ++
Sbjct: 85 AVEGTDFVQENTPERSDVKRALFAELDRLVPADVLVGSSTSSLPISDLQAGLSTAARFVL 144
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
HP NP + +PLVE+ T P +G++PV L RE+ G + NR+ A+
Sbjct: 145 GHPFNPVHLIPLVEVGGGDATDPAAVDTALAFYAALGKEPVRLNREVFGHIGNRLTSAMF 204
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLN--AEGMQSYIDRYGETIYR 218
E RL + G +++A G T H + A G+ ++ ++ I +
Sbjct: 205 REAVRLVAEGYASVEDVDKAIRFGPALKWAIQGQFTTFHTSGGAGGLAEFLPKFVPGILK 264
Query: 217 VSNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCLMRLSLL 68
M P + + + Q+E +++ +D LM + L
Sbjct: 265 RWETMADPP-LGDPALQAELVRQMEAATDGRSVEEIARRQDALLMAMLAL 313
>UniRef50_Q7D836 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=8; Mycobacterium tuberculosis complex|Rep:
3-hydroxyacyl-CoA dehydrogenase family protein -
Mycobacterium tuberculosis
Length = 304
Score = 85.4 bits (202), Expect = 1e-15
Identities = 49/158 (31%), Positives = 84/158 (53%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ A V E V ENL +K+++F+ L ++ D + +E ++ S+VI
Sbjct: 70 AIPDADLVIEAVVENLAVKQELFERLATLAPD-AVLATNTSVLPIGAVTERVEDGSRVIG 128
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+H NPP +P+VE+VP+ T P+ A + ++ ++G+ PV + R++ GF+ NR+Q+A+
Sbjct: 129 THFWNPPDLIPVVEVVPSARTAPDTADRVVALLTQVGKLPVRVGRDVPGFIGNRLQHALW 188
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETA 278
E L V+ +G+R A LG LE A
Sbjct: 189 REAIALVAEGVCDPKTVDLVVRNTIGLRLATLGPLENA 226
>UniRef50_Q0LRY2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Caulobacter sp. K31
Length = 348
Score = 83.4 bits (197), Expect = 5e-15
Identities = 48/160 (30%), Positives = 77/160 (48%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A FV E V E LD+K+++F L + + +EGL +++++
Sbjct: 111 AVADAAFVFESVSEKLDVKRRIFSALAECARHDAVLASNTSAIPITQIAEGLPCEARIVG 170
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
SH NP VPLVE+VP T + +++ +G++ V + R+I GFV NR+Q+A+
Sbjct: 171 SHWWNPADVVPLVEVVPGIATDAHHVEAMMQLLISVGKKAVRIDRDIPGFVGNRLQFALW 230
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
E L ++ G R + LG +E A L
Sbjct: 231 REAQSLVANGVCDAETLDEIVKSSFGPRLSVLGPMENADL 270
>UniRef50_Q0RVG8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 288
Score = 83.0 bits (196), Expect = 7e-15
Identities = 47/160 (29%), Positives = 78/160 (48%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+G+ + E V ENL++K+ +F ++ ++T ++ L ++++
Sbjct: 58 AVEGSSLLFEAVVENLEVKRDLFAEIERF-SESTPIASNTSTFTPSELAKNLCEPGRLVI 116
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+H NP VPLVE+VP+P T+P+V + G+ V L RE GFV NR+Q A++
Sbjct: 117 AHFFNPAEVVPLVEVVPSPDTRPDVVSAVTSALVAAGKTVVPLNREAPGFVANRLQAALV 176
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
E L V++ LG R+A G + L
Sbjct: 177 REAMALVRANVATAEMIDAVVTSSLGPRWAAAGPFKVMDL 216
>UniRef50_Q1DAC1 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Myxococcus xanthus DK 1622|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Myxococcus xanthus
(strain DK 1622)
Length = 321
Score = 82.6 bits (195), Expect = 9e-15
Identities = 42/153 (27%), Positives = 75/153 (49%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E +PE+L LK+++F+ LD + +T+ + +V+ +H P
Sbjct: 90 VIESIPEDLALKQQLFRELDQLAAPDTLLATNTTALSVTAIARDCTRPERVLSAHYYLPA 149
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
+ +PLV+I+P T P+ + R +EE+G+ PV +R++ G V R+Q A++ E RL
Sbjct: 150 HLIPLVDIIPGEKTSPDAVETVRRFIEELGKSPVVFSRDVPGSVGPRLQQALIGEAIRLV 209
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
V+++G+G R G + L
Sbjct: 210 HEGVATPEMVDRVLTQGVGRRLGASGVFDRLDL 242
>UniRef50_Q978T2 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Archaea|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Thermoplasma volcanium
Length = 659
Score = 81.8 bits (193), Expect = 2e-14
Identities = 40/115 (34%), Positives = 66/115 (57%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
+VK A V E VPE LD+K++VF LD ++ I +EG+K K +V+
Sbjct: 78 SVKDADLVIEAVPEILDIKRQVFAQLDQSTKEDAILATNTSNIRLTEIAEGVKKKGKVVG 137
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H NPP + LVE++ + +T+ EV + + ++IG+ P+ + ++ GFV+NRI
Sbjct: 138 MHFFNPPVVLKLVEVIRSDYTEDEVFEAVYDFSKKIGKIPIKVYKDTPGFVVNRI 192
>UniRef50_A4SW27 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Polynucleobacter sp. QLW-P1DMWA-1
Length = 313
Score = 79.4 bits (187), Expect = 9e-14
Identities = 44/157 (28%), Positives = 71/157 (45%), Gaps = 1/157 (0%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V ECVPE LD+K+++F L+ + + GLK +++I H P
Sbjct: 83 VIECVPERLDIKQELFAKLEKYAKPEAVLASNSTSFPISEIASGLKTAARMIGLHFFMPA 142
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
+ VP VE+V T P V +M G PV++ +++ GF+ NR+Q+A+ E + +
Sbjct: 143 HLVPCVEVVYGEKTSPMVGDSLSRLMTACGMVPVTVKKDLPGFLANRLQHALSREAFAMV 202
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLG-ALETAHLNAE 263
+ G G RY G A++ H E
Sbjct: 203 DAGICTPEDIDKAVRFGFGFRYIAAGPAMQRDHAGLE 239
>UniRef50_Q89HA7 Cluster: Blr6087 protein; n=6; Proteobacteria|Rep:
Blr6087 protein - Bradyrhizobium japonicum
Length = 330
Score = 78.6 bits (185), Expect = 2e-13
Identities = 51/175 (29%), Positives = 78/175 (44%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
TA+ A V E VPE ++LK++V V +TI S + + + +
Sbjct: 89 TALADAGMVFEGVPEVVELKREVLGAASRQVKPDTIIASTTSTILVDDLSGAIVNPHRFL 148
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H +NP Y +PLVE+ P T P + + + ++E IG+ PV + GF++ RIQ
Sbjct: 149 NVHWLNPAYLIPLVEVSPGKATDPAIIDEVKALLEGIGKVPV-VCAATPGFIVPRIQALA 207
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGE 230
++E R+ + G G RYA LG LE + Y RY E
Sbjct: 208 MNEAARMVEEGVASAEEIDKAIRYGFGFRYAVLGLLEFIDWGGGDILYYASRYLE 262
>UniRef50_Q62DG4 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=48; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Burkholderia mallei
(Pseudomonas mallei)
Length = 331
Score = 78.2 bits (184), Expect = 2e-13
Identities = 53/223 (23%), Positives = 93/223 (41%), Gaps = 2/223 (0%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
V A FVQE PE LK ++ + + + I + IV
Sbjct: 91 VADADFVQESAPEREALKLELHERISRAAKPDAIIASSTSGLLPTDFYARAHRPERCIVG 150
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
HP NP Y +PLVE++ T P+ I +G +P+ + +E+ GF+ +R+ A+
Sbjct: 151 HPFNPVYLLPLVEVLGGERTAPDTVDAALGIYRALGMRPLRVRKEVPGFIADRLLEALWR 210
Query: 388 EVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL--NAEGMQSYIDRYGETIYRV 215
E L + G G+R++F+G T L GM+ ++ ++G +
Sbjct: 211 EALHLVDEGVATTGEIDDAIRFGAGIRWSFMGTFLTYTLAGGEAGMRHFMQQFGPALELP 270
Query: 214 SNEMGPAPRMTTNKSRNSVCEQLEKLVPIEKLQDRRNWRDLCL 86
++ AP++T V E+ P ++ +RD C+
Sbjct: 271 WTKL-VAPKLTDALIDRVVEGTAEQQGP-RSIKALERYRDECI 311
>UniRef50_UPI00015BAF7B Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Ignicoccus hospitalis KIN4/I|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Ignicoccus hospitalis KIN4/I
Length = 683
Score = 77.8 bits (183), Expect = 3e-13
Identities = 40/122 (32%), Positives = 62/122 (50%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A K FV E VPE L+LK+ VF LD + I ++ K +V+
Sbjct: 106 AAKDVDFVIEAVPEKLELKRAVFSVLDKYAPPHAILASNTSSIPITEIAKATKRPDKVVG 165
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NPP + LVE+V T E K T E+ +++G+ P+ + +++ GF++NRI L
Sbjct: 166 MHFFNPPVILKLVEVVRGKETSDETVKITVELAKKMGKVPIVVNKDVPGFIVNRIMARFL 225
Query: 391 DE 386
+E
Sbjct: 226 NE 227
>UniRef50_Q28KL8 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=2; Bacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase NAD-binding - Jannaschia sp. (strain CCS1)
Length = 466
Score = 77.8 bits (183), Expect = 3e-13
Identities = 53/192 (27%), Positives = 86/192 (44%), Gaps = 2/192 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A +VQE VPE LD+K KV L ++ + +E ++VIV
Sbjct: 73 AVGDADWVQESVPERLDIKHKVHAELTTLAPGRAVIGSSTSGFKPSELTE---KGARVIV 129
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+HP NP Y +PL+E+V + K EI+ IG P+ + +EID + +R A+
Sbjct: 130 AHPFNPVYLLPLIELVG----DTDHCAKAAEILRGIGMYPLHVRKEIDAHIADRFLEAVW 185
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL--NAEGMQSYIDRYGETIYR 218
E L + G G+R+A +G ET + GM+ ++ ++G +
Sbjct: 186 REALWLVKDGIATTEEIDEAIRMGFGLRWAQMGLFETYRVAGGEAGMKHFMAQFGPCLTW 245
Query: 217 VSNEMGPAPRMT 182
++ P T
Sbjct: 246 PWTKLMDVPEFT 257
>UniRef50_Q24N80 Cluster: Putative uncharacterized protein; n=1;
Desulfitobacterium hafniense Y51|Rep: Putative
uncharacterized protein - Desulfitobacterium hafniense
(strain Y51)
Length = 313
Score = 77.8 bits (183), Expect = 3e-13
Identities = 44/151 (29%), Positives = 70/151 (46%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V E V EN D+K++ F LD + + I + + H + I++H
Sbjct: 85 ADLVLESVFENADVKRETFAQLDKLCASDCILCSNTSASNIFEIAP-VSHPERQIITHYF 143
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
NPP+ + LVE+V P T E K + + ++G++P L + I GF++NRI AI E
Sbjct: 144 NPPFIMDLVEVVMGPKTSDETLDKVKSFLIQVGKEPAVLKQYIPGFIVNRIATAITREAG 203
Query: 379 RLXXXXXXXXXXXXXVMSEGLGMRYAFLGAL 287
+ + G+RYAF G +
Sbjct: 204 YMVTQGWVSAQDIDSAIRNTSGIRYAFEGPM 234
>UniRef50_Q46MP3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Burkholderiales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Ralstonia eutropha (strain JMP134) (Alcaligenes
eutrophus)
Length = 304
Score = 77.4 bits (182), Expect = 4e-13
Identities = 45/157 (28%), Positives = 76/157 (48%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
V+ V E PE++ K+++ + +D +V+ I +EG +V+ +
Sbjct: 76 VRDCDIVVEAAPESVSTKRELIREID-LVNSECIIASNTSVLRITEIAEGSADPGRVVGT 134
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H NPPY +PLVE+V T+ VAK+ + + + G+ PV + R++ GFV NR+Q+A++
Sbjct: 135 HWWNPPYLMPLVEVVRGELTREGVAKQVSQWLSKAGKTPVDVYRDVPGFVGNRMQFALVR 194
Query: 388 EVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETA 278
E + V G R A +G L A
Sbjct: 195 EAAHIVEQGICSAETVDLVARLTFGRRLAAVGPLRNA 231
>UniRef50_A0RUN1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase; n=4; Crenarchaeota|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase - Cenarchaeum
symbiosum
Length = 365
Score = 77.4 bits (182), Expect = 4e-13
Identities = 40/146 (27%), Positives = 66/146 (45%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A++GA V E VPE +DLK+KV+ LD+ + ++ + I
Sbjct: 67 ALEGADLVIEAVPEVMDLKRKVYAELDAAAPEGAAFASNTSTLPITEIAQATSRPERFIG 126
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NPP + LVE++P T E + T E +E +G+Q V +++ GF++NR+ ++
Sbjct: 127 IHFFNPPQLMKLVEVIPGEGTSDETTRMTLEYVESLGKQAVLCRKDVPGFIVNRLFIPMV 186
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLG 314
E + GLG
Sbjct: 187 HEACHAMDRTGASMEQIDSAVKFGLG 212
>UniRef50_Q7WCB1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bordetella|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bordetella parapertussis
Length = 354
Score = 77.0 bits (181), Expect = 5e-13
Identities = 47/172 (27%), Positives = 76/172 (44%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A A V E VPE L LK+ +F LD++ D I ++ + + + +
Sbjct: 119 AACSAQLVIEAVPEKLALKRDIFARLDTLCDPQAIFATNTSGLSINDIAQAVTRRDRFVG 178
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+H P +PLVE+V T + + ++ G++PV + ++I GF+ NRIQ+A+
Sbjct: 179 THFFTPADVIPLVEVVRNDDTSEQTVARVMGMLRAGGKRPVLVRKDIPGFIANRIQHALA 238
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRY 236
E L V+ LG+R A G LE +N + I Y
Sbjct: 239 REAISLLEKGVASAEDIDEVVKWSLGIRLALSGPLEQRDMNGIDVHYAIASY 290
>UniRef50_A4SW21 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Polynucleobacter sp.
QLW-P1DMWA-1|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Polynucleobacter sp.
QLW-P1DMWA-1
Length = 310
Score = 74.1 bits (174), Expect = 3e-12
Identities = 51/186 (27%), Positives = 83/186 (44%), Gaps = 1/186 (0%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V ENL LK+ +F +LD + + + L ++ +H P
Sbjct: 79 VIESVSENLGLKRLIFSDLDQRLPSHIPIGSNTSGFPISDITASLPTAHRMFNTHYFMPA 138
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
+ VPLVE+V + PE+AK ++ + ++PV + ++I GF+ NRIQ+A++ EV L
Sbjct: 139 HIVPLVEVVLGKTSDPELAKTVCQLFQAHHKKPVLVKKDIPGFLANRIQHALMREVLSLV 198
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA-EGMQSYIDRYGETIYRVSNEMGPA 194
+ G RYA +G + ++ EGM E IY + +
Sbjct: 199 DEGIATPDDIDTAVRYSFGFRYAAVGPMTQKEISGWEGMA----LAAELIYPSLSNITAP 254
Query: 193 PRMTTN 176
P TN
Sbjct: 255 PACVTN 260
>UniRef50_Q0FUM2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Rhodobacterales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Roseovarius sp. HTCC2601
Length = 220
Score = 72.9 bits (171), Expect = 8e-12
Identities = 36/127 (28%), Positives = 71/127 (55%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
+A++G V E V E+L++K+ +F L+ + +N + + + K +++
Sbjct: 85 SAIEGVFLVHEAVQESLEVKQALFAELERICPENVVLATNTSSFLISDIAAQMTRKERMM 144
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H V P + VP++E++ A T E+ +R +++ I V++ E GF++NRIQ+A+
Sbjct: 145 GIHYVTPGHIVPVIELIHAADTPAELVAWSRMLVQNIEHVGVAIL-ERPGFLVNRIQFAM 203
Query: 394 LDEVWRL 374
L E++RL
Sbjct: 204 LTEIYRL 210
>UniRef50_Q02A28 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Solibacter usitatus Ellin6076|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Solibacter usitatus (strain Ellin6076)
Length = 309
Score = 72.5 bits (170), Expect = 1e-11
Identities = 44/161 (27%), Positives = 71/161 (44%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V E PE + K+++F +D V + + + QV+ +H
Sbjct: 79 ADIVIESGPEEMGWKQELFARMDRVARADAVLASNTSGLSVTAIAAECARPEQVLATHFW 138
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
NPP+ VPLVEI+ T P A RE++ G+ PV + + G + NR+Q A++ E
Sbjct: 139 NPPHLVPLVEIIQGRATSPAAAAAVRELLTACGKTPVVVKLDRPGQLGNRLQMALVREAA 198
Query: 379 RLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGM 257
+ V+ GLG+R G E H++ G+
Sbjct: 199 NIVAEGIADAEAVDSVVKNGLGIRMPAYGIFE--HMDVAGL 237
>UniRef50_A0JTB4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 333
Score = 69.3 bits (162), Expect = 9e-11
Identities = 40/160 (25%), Positives = 70/160 (43%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A F++E VPE + +K + + + + I SE + + + +
Sbjct: 96 AVADADFIEEAVPEIIAIKHQTLARISAAARPDAIIGSNTSTISIADLSEPVTNPERFLG 155
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP ++P VEI+P T R+++ G+Q ++ +++ GFVLNR+QYA+
Sbjct: 156 VHFSNPSPFIPGVEIIPHAGTSATTVGAVRDLVHAAGKQ-TAVVKDVTGFVLNRLQYALF 214
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
E +L ++ G R F G A +
Sbjct: 215 HEAAQLVEQGIATADDVDTLVRTTFGFRLPFFGPFAIADM 254
>UniRef50_A1SPQ6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Nocardioides sp. (strain BAA-499 / JS614)
Length = 287
Score = 68.1 bits (159), Expect = 2e-10
Identities = 40/126 (31%), Positives = 58/126 (46%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A A V E V E +++K ++F LD + TI + +V
Sbjct: 80 AAADADLVIEAVVERIEVKSELFAELDRLCPPATILASNSSSFVPSRLAAATGRADRVCN 139
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + VE+VP P T + +++E +G+ PV L +EI GFV NRI A+
Sbjct: 140 LHFFNPALVMACVEVVPGPETSGQTVASCVDLVESLGKVPVVLEKEIPGFVANRILNAVR 199
Query: 391 DEVWRL 374
DE RL
Sbjct: 200 DEAIRL 205
>UniRef50_Q11E57 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Mesorhizobium sp. BNC1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Mesorhizobium sp. (strain BNC1)
Length = 485
Score = 66.9 bits (156), Expect = 5e-10
Identities = 41/144 (28%), Positives = 63/144 (43%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A E + E LD+K+KVF L++++ ++ I LK +++ H
Sbjct: 88 AALTVEAIVERLDVKQKVFAQLEAILAEDAILATNTSSISITAIGAALKRPERLVGMHFF 147
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
NP + LVE+V T PEVA+ T G+ V + + GF++NR+ A E
Sbjct: 148 NPAPIMKLVEVVSGLATSPEVAQITHATARAWGKTAVHV-KSTPGFIVNRVARAFYGEPL 206
Query: 379 RLXXXXXXXXXXXXXVMSEGLGMR 308
RL +M EG G R
Sbjct: 207 RLAEEGMADIATLDALMREGGGFR 230
>UniRef50_O28011 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 668
Score = 66.5 bits (155), Expect = 7e-10
Identities = 34/116 (29%), Positives = 59/116 (50%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AVK A V E VPE +++KK+V++ +D + + I ++ +
Sbjct: 92 AVKDADLVIEAVPEVVEIKKQVWEEVDKLAKPDCIFTSNTSTMRITMLADFTSRPEKFAG 151
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQ 404
H NPP + LVE++ T EV E ++ IG+ PV + +++ GF++NR+Q
Sbjct: 152 LHFFNPPVLMRLVEVIRGEKTSDEVMDLLVEFVKSIGKTPVRVEKDVPGFIVNRVQ 207
>UniRef50_Q5L0D2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 281
Score = 66.1 bits (154), Expect = 9e-10
Identities = 48/160 (30%), Positives = 68/160 (42%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+GA V E VPENL LKK VFQ LD + + I + VI
Sbjct: 79 AVRGADVVIEAVPENLALKKDVFQQLDQLAKPDAILATNTSELSVTALAAATNRPENVIG 138
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + L+EIV T + R + E+G++ V + ++ GFV R A +
Sbjct: 139 MHWFNPAPVMKLIEIVKGETTSDDTVDAIRRLSVELGKETV-VVKDRQGFVTTRALAAHM 197
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
E R+ + LG+ Y +G LE A +
Sbjct: 198 IECIRMYEEGVASAEDIDKAVR--LGLNYP-MGPLELADM 234
>UniRef50_Q9YBW6 Cluster: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase; n=19;
cellular organisms|Rep: 3-hydroxyacyl-CoA
dehydrogenase/3-hydroxybutyryl-CoA dehydratase -
Aeropyrum pernix
Length = 669
Score = 66.1 bits (154), Expect = 9e-10
Identities = 32/115 (27%), Positives = 58/115 (50%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ + F+ E +PE L+LK+++F D + I + +V+
Sbjct: 90 ALSESDFMIEAIPEKLELKQQLFAFADKHAKETAILASNTSSLPITEIAAATSRPEKVVG 149
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H NPP +PLVE+V T E T ++ +++G+Q V + +++ GF++NRI
Sbjct: 150 MHFFNPPVLMPLVEVVKGEKTSEETVAATVDLAKKMGKQTVVVKKDVPGFIVNRI 204
>UniRef50_O30218 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 661
Score = 66.1 bits (154), Expect = 9e-10
Identities = 36/120 (30%), Positives = 57/120 (47%)
Frame = -2
Query: 745 KGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSH 566
K A V E +PE DLKKKVF ++ D+TI +E K + I H
Sbjct: 84 KDADLVIEAIPEIFDLKKKVFSEIEQYCPDHTIFATNTSSLSITKLAEATKRPEKFIGMH 143
Query: 565 PVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
NPP + L+EIV T E + + +I + + + +++ GF++NRI + +E
Sbjct: 144 FFNPPKILKLLEIVWGEKTSEETIRIVEDFARKIDRIIIHVRKDVPGFIVNRIFVTMSNE 203
>UniRef50_A0LPA1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 287
Score = 65.7 bits (153), Expect = 1e-09
Identities = 34/116 (29%), Positives = 56/116 (48%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNP 554
FV E V E++ +K+KVF LD++ TI +E + +V+ H NP
Sbjct: 85 FVIESVIEDIAIKRKVFAELDNLSPPETILATNTTSLSISAMAEATRRPERVVQMHFFNP 144
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
P + LVEI+P T E + E ++G+ PV E +++R+ +L+E
Sbjct: 145 PVIMKLVEIMPGKKTSRETVEAAAEFARQLGKDPVVCKNEAPAGIVSRVLGQLLNE 200
>UniRef50_Q4J6T7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Archaea|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Sulfolobus acidocaldarius
Length = 657
Score = 65.3 bits (152), Expect = 2e-09
Identities = 34/109 (31%), Positives = 56/109 (51%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNP 554
F+ E E D+K+K+F LD VV + I +E + + I H +NP
Sbjct: 85 FIIEAAIERSDVKRKIFSELDRVVKKDAIFATNTSTIPISYLAEVTGRQEKFIGLHFMNP 144
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
P +PLVEI+ T E K T ++ ++I + V + +++ GF++NRI
Sbjct: 145 PVLMPLVEIIMGNKTAEETLKTTIDLAKKINKDYVVVKKDVPGFLINRI 193
>UniRef50_Q9HKW7 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase;
n=2; Thermoplasmatales|Rep: Probable 3-hydroxyacyl-CoA
dehydrogenase - Thermoplasma acidophilum
Length = 291
Score = 64.9 bits (151), Expect = 2e-09
Identities = 36/114 (31%), Positives = 55/114 (48%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
++ A V E VPENLDLK+KVF +++ V +N I ++ LK K + I
Sbjct: 82 SLSDADIVVEAVPENLDLKRKVFIDIEKNVSENAIIASNTSGITIAEIAQDLKKKDRAIG 141
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 410
H NP + L+E+V A T + + IG+ PV + ++ GF R
Sbjct: 142 MHWFNPAGIMKLIEVVRAKMTSEDTISTVVDFSRRIGKTPV-VVADVPGFFTTR 194
>UniRef50_Q8XI27 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
NAD-dependent; n=9; Clostridiales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase NAD-dependent -
Clostridium perfringens
Length = 282
Score = 64.5 bits (150), Expect = 3e-09
Identities = 35/115 (30%), Positives = 55/115 (47%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E EN+++KK++F LD + + TI + +VI H NP
Sbjct: 84 VIEAAVENMEIKKQIFAELDKICKEETILASNTSSLSITEVASATNRPDRVIGMHFFNPA 143
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+ LVE++ T E K + + E IG+ PV + E GFV+NRI +++E
Sbjct: 144 TIMKLVEVIRGMATSQETFDKVKAMSEAIGKTPVEVA-EAPGFVVNRILIPMINE 197
>UniRef50_Q5KYB5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=6;
Bacillaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 287
Score = 64.5 bits (150), Expect = 3e-09
Identities = 39/124 (31%), Positives = 60/124 (48%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+ A V E VPE L+LKK+VF+ +D+ + K +VI
Sbjct: 79 AVRDADLVIEAVPEKLELKKQVFETIDAHAPASCYFATNTSTMSPTEIGSFTKRPERVIA 138
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + + LVEI+ T E A+ +E E +G++ V + E GFV +RI +
Sbjct: 139 MHFFNPVHKMKLVEIIRGLETSDETAQVAKEAAERMGKETV-VVNEFPGFVTSRISALVG 197
Query: 391 DEVW 380
+E +
Sbjct: 198 NEAF 201
>UniRef50_Q9KBD3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=8;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus halodurans
Length = 287
Score = 64.1 bits (149), Expect = 4e-09
Identities = 31/111 (27%), Positives = 56/111 (50%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V E V ENLD+KK+VF LD+ + ++TI + +V+ H
Sbjct: 83 ADLVIEAVIENLDVKKEVFHTLDTCLANDTIIATNTSSMSITEIAAATNRPDRVVGMHFF 142
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
NP + LVE+V T + + ++ ++ ++P+ + ++ GF++NRI
Sbjct: 143 NPAQLMKLVEVVRGYQTSDDTVETVKQFARQLKKEPIEVKKDTPGFIVNRI 193
>UniRef50_Q2B4D1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Firmicutes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Bacillus sp. NRRL B-14911
Length = 295
Score = 63.7 bits (148), Expect = 5e-09
Identities = 38/126 (30%), Positives = 58/126 (46%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AVK A F+ E V E L++K++VF L+ + + I + + +
Sbjct: 84 AVKSADFIIEAVVEKLEVKREVFSMLEEMAPPHAIFATNSSTIVNSLLANAADRPEKTVN 143
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H PP + VE+V + T E A+ E+ I + V L +EI GFV NRI A+
Sbjct: 144 MHFFFPPLVMDCVEVVMSSRTSEETAETAMEVCNAINRTAVLLKKEISGFVANRILGALQ 203
Query: 391 DEVWRL 374
E +L
Sbjct: 204 REAVQL 209
>UniRef50_Q0YNQ2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=3; Geobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Geobacter sp. FRC-32
Length = 289
Score = 63.7 bits (148), Expect = 5e-09
Identities = 39/147 (26%), Positives = 69/147 (46%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
++K F+ E V E++++KK++F LD+V D+TI + +K+ + I
Sbjct: 82 SLKDVPFIFEAVFEDINVKKELFAKLDAVCGDDTIYATNTSSISITEMAALVKNPANFIG 141
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + LVE++PA T P E+ ++IG+ ++ ++ GFV+NR+ +
Sbjct: 142 MHFFNPVPVMKLVEVIPALQTAPATKDLALEMAKKIGKTAIT-CKDTPGFVVNRLFVPYI 200
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGM 311
+ RL M G M
Sbjct: 201 IDAVRLLEEGVASAEDIDTAMKLGCNM 227
>UniRef50_Q392L7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=9;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 336
Score = 63.3 bits (147), Expect = 6e-09
Identities = 43/172 (25%), Positives = 70/172 (40%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+ A V E +PE LD K + L VD + +++
Sbjct: 93 AVRDADIVFEALPEVLDAKADALRWLGEHVDARATIASTTSTFVVTELQRHVVRPERMLN 152
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+H +NP +PLVEI + T V ++E +G++PV + G+++ RIQ +
Sbjct: 153 AHWLNPALLMPLVEISRSDATDQSVVDALAALLERVGKKPV-ICGPAPGYIVPRIQALAM 211
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRY 236
+E R+ + G G R+A LG LE + Y +Y
Sbjct: 212 NEAARMVEEGVASAEDIDTAIRTGFGPRFAVLGLLEFIDWGGCDILYYASKY 263
>UniRef50_Q5V0V6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Halobacteriaceae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 654
Score = 63.3 bits (147), Expect = 6e-09
Identities = 31/122 (25%), Positives = 59/122 (48%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A V E PE L +K+ +F+++D+ + + + + V+
Sbjct: 84 AVSDADLVIEAGPEQLSVKQDIFESVDAAAPADALLATNSSSLSITEIAAATERPESVLG 143
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NPP + LVE++ T E A++ E +E +G+ P+ + +++ GFV+N + +
Sbjct: 144 LHFFNPPVKMDLVEVIYGKATTDETAQRGYEFIESLGKTPIYVRKDVRGFVVNSVLGPFM 203
Query: 391 DE 386
E
Sbjct: 204 SE 205
>UniRef50_Q397D0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=31;
Proteobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 518
Score = 62.9 bits (146), Expect = 8e-09
Identities = 41/145 (28%), Positives = 62/145 (42%)
Frame = -2
Query: 742 GAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHP 563
GA + E E LD+K+++F L+ VDD + + GL+ +V H
Sbjct: 96 GAALIVEAAAERLDVKREIFATLERHVDDACLLATNTSSISITSIAAGLRVPQRVAGLHF 155
Query: 562 VNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEV 383
NP + LVE+V T PEVA+ G++PV + + GF++NR+ E
Sbjct: 156 FNPAPLMALVEVVSGLATAPEVAQVLYATAAAWGKRPV-MAKSTPGFIVNRVARPYYAEA 214
Query: 382 WRLXXXXXXXXXXXXXVMSEGLGMR 308
R+ VM E G R
Sbjct: 215 LRVLNEQGGAPASIDAVMREAGGFR 239
>UniRef50_A4ALU9 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like
protein; n=1; marine actinobacterium PHSC20C1|Rep:
3-hydroxyacyl-CoA dehydrogenase-like protein - marine
actinobacterium PHSC20C1
Length = 288
Score = 62.9 bits (146), Expect = 8e-09
Identities = 35/126 (27%), Positives = 58/126 (46%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ G E VPE L LK+KVF +LD + + KH +V+
Sbjct: 80 ALVGVEAAIEAVPEVLALKQKVFTDLDERTGPEVMLATNTSQLSITTIASSAKHPERVVG 139
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NPP + LVEI+ T E+ ++ + +++G++ + R+ GF+ R A+
Sbjct: 140 MHFFNPPVVMRLVEIIRGTMTSDEMLQRAIDFSDQLGKENIVCQRDTPGFITTRAIMALR 199
Query: 391 DEVWRL 374
E R+
Sbjct: 200 LECIRI 205
>UniRef50_A6ERZ1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
unidentified eubacterium SCB49|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - unidentified eubacterium SCB49
Length = 403
Score = 62.5 bits (145), Expect = 1e-08
Identities = 34/117 (29%), Positives = 59/117 (50%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E + E+L +KKKVFQ L+S V D+ I + L+ + + H NP
Sbjct: 102 EAIIEDLGIKKKVFQELESYVSDSCIIASNTSSLSIASIASSLQKPERCVGIHFFNPAPL 161
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
+ LVE++PA T V K + E ++ ++ V++ ++ GF++NR+ E R+
Sbjct: 162 MKLVEVIPAIQTSDAVLKISEETIKS-WKKVVAVAKDTPGFIVNRVARPFYGEALRI 217
>UniRef50_Q5V357 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Halobacteriaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Haloarcula marismortui (Halobacterium marismortui)
Length = 669
Score = 62.5 bits (145), Expect = 1e-08
Identities = 32/122 (26%), Positives = 57/122 (46%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV V E VPE +++KK V+ ++ +N I SE + Q
Sbjct: 98 AVSDVDVVIEAVPEKMEIKKDVYTEVEEHAPENAIFATNTSSLSITELSEVTERPEQFCG 157
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NPP + LVE++ + + + + E+ G+ PV + ++ GF++NRI ++
Sbjct: 158 MHFFNPPVRMQLVEVISGAHSGDDTLEAIEALAEDFGKTPVRVRKDSPGFIVNRILVPLM 217
Query: 391 DE 386
+E
Sbjct: 218 NE 219
>UniRef50_Q9HJM0 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase
related protein; n=3; Thermoplasmatales|Rep:
Beta-hydroxybutyryl-CoA dehydrogenase related protein -
Thermoplasma acidophilum
Length = 314
Score = 62.1 bits (144), Expect = 1e-08
Identities = 41/158 (25%), Positives = 70/158 (44%), Gaps = 5/158 (3%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E EN D+K ++F ++ S + ++ I S LK ++ H NPP
Sbjct: 115 VIEAAFENQDVKNRIFSDI-SDLSEHAIIASNTSSLSITEMSSRLKRPENALILHFFNPP 173
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEI-----GQQPVSLTREIDGFVLNRIQYAILDE 386
Y +PLVE+VP+ +T E ++ + G PV + +E +GF++NR+ +++
Sbjct: 174 YLLPLVEVVPSLYTSDEAKNTAVSLISRMKNHREGMVPV-MAKEREGFIVNRLLIPLINS 232
Query: 385 VWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
L M +G G +G LE A +
Sbjct: 233 ASDLLDSGVASAEDIDTAMKKGAGFP---MGPLELADM 267
>UniRef50_Q5KVJ3 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=16;
Bacillaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Geobacillus kaustophilus
Length = 795
Score = 61.3 bits (142), Expect = 3e-08
Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 3/117 (2%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVIVSHPV 560
++ E V E L++KK+VF +D V TI +EG K + +H
Sbjct: 103 WIIEAVVEKLEVKKEVFARVDEVRTPGTIVSSNTSGISIAAMAEGRSDDFKKHFLGTHFF 162
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI-QYAIL 392
NPP Y+ L+EI+P T P+V + E++ + V + ++ F+ NRI Y +L
Sbjct: 163 NPPRYLKLLEIIPTEHTDPDVVAYMKSFGEDVLGKGVVMAKDTPNFIANRIGTYGLL 219
>UniRef50_A0JVH8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=12; Actinomycetales|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Arthrobacter sp. (strain FB24)
Length = 723
Score = 61.3 bits (142), Expect = 3e-08
Identities = 44/155 (28%), Positives = 68/155 (43%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A A FV E V E L++KK+VF ++++V I + L H +++
Sbjct: 425 AFADADFVIEAVFEELNVKKQVFAEVEAIVSPECILATNTSSLSVTAMAADLAHPERLVG 484
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP +PL+EIV AP T V E+ + + + V L ++ FV+NRI ++
Sbjct: 485 FHFFNPVAVMPLLEIVRAPKTDDAVLATAFELAKGLKKTAV-LVKDAAAFVVNRILLRLM 543
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGAL 287
EV + GL M LGA+
Sbjct: 544 GEVTAAFDEGTPAEVADNALRPMGLPMTPFTLGAM 578
>UniRef50_Q1AV58 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 377
Score = 60.1 bits (139), Expect = 6e-08
Identities = 42/169 (24%), Positives = 69/169 (40%)
Frame = -2
Query: 742 GAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHP 563
GA V E V E++ +K++VF+ L+ VV + + S + +V+ H
Sbjct: 81 GASLVIEAVVEDIGVKREVFRTLERVVGEEAVLATNTSSLSVAEISATTRRPERVVGMHF 140
Query: 562 VNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEV 383
NP + LVE+V P + E + E +G+ PV ++ + GF++NR+ E
Sbjct: 141 FNPAPVMRLVEVVRGPRSGEEALARAEEAARRMGKTPVRVS-DTPGFIVNRVARPFYLEA 199
Query: 382 WRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRY 236
RL + G M L L +N +S RY
Sbjct: 200 LRLAETGESPARIDASLRERGFRMGPLELADLIGQDVNLAVSESLFRRY 248
>UniRef50_A2TU34 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Flavobacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Dokdonia donghaensis MED134
Length = 394
Score = 59.7 bits (138), Expect = 8e-08
Identities = 35/118 (29%), Positives = 57/118 (48%), Gaps = 1/118 (0%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E + ENL++KKKVFQ L++ V D I + L++ + I H NP
Sbjct: 87 EAIVENLEVKKKVFQELETYVSDTAIIASNTSSLSIASIAASLQNPERCIGIHFFNPAPL 146
Query: 544 VPLVEIVPAPWTKPEVAKK-TREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
+ LVE++PA T V EI ++ V++ ++ GF++NR+ E R+
Sbjct: 147 MKLVEVIPAVQTSQNVLDTCVAEITR--WKKVVAIAKDTPGFIVNRVARPFYGEALRM 202
>UniRef50_A0LSM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 301
Score = 59.7 bits (138), Expect = 8e-08
Identities = 46/180 (25%), Positives = 75/180 (41%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V E LD+K+ VF L ++V N + + G+ +V+ H +P
Sbjct: 90 VVEAVYEELDVKRVVFAELAAIVRPNVLLASNTTAIPITHIASGVSGPQRVVGMHFFSPV 149
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
+ L EIV T + + R E +G+ + + R++ GFV +R+ A ++E RL
Sbjct: 150 PVMQLCEIVRGLQTDDDTVARARRFAESLGKTCIVVNRDVAGFVTSRLLVAFVNEALRLV 209
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRVSNEMGPAP 191
G G +G L T L+ G+ I E IY+ + + AP
Sbjct: 210 ESGIATPEDIDTACRLGFGHA---MGPLAT--LDLTGL-DVIAHAAEAIYQATRDPKFAP 263
>UniRef50_Q891F6 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=3;
Bacteria|Rep: 3-hydroxybutyryl-coA dehydrogenase -
Clostridium tetani
Length = 282
Score = 59.3 bits (137), Expect = 1e-07
Identities = 33/115 (28%), Positives = 53/115 (46%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E EN+++K+++F LD + TI + +VI H NP
Sbjct: 84 VVEAAIENMEIKREIFAELDRICKPETILSSNTSSLSITEIATATNRPDKVIGMHFFNPA 143
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+ L+EI+ T E +E+ IG+ PV + E GFV+NRI +++E
Sbjct: 144 PVMKLIEIIRGMATSQETFDAVKEVSVAIGKDPVEVA-EAPGFVVNRILIPMINE 197
>UniRef50_A1SEZ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Nocardioides sp. JS614|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Nocardioides sp. (strain BAA-499 /
JS614)
Length = 275
Score = 58.8 bits (136), Expect = 1e-07
Identities = 43/179 (24%), Positives = 75/179 (41%), Gaps = 2/179 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
+++ A V E VPE L LK ++FQ L T+ +E S+V+
Sbjct: 69 SLETAEVVIEAVPEILPLKTQIFQQLRGA-PPGTLLVSNTSTMSISALAEACGGSSRVVG 127
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + +PLVE+V T + + + +G+ P+ + R++ GFV +R+ +
Sbjct: 128 MHFFNPAHRMPLVEVVVGTRTSDDARDRAVALAVRLGKDPI-VVRDLPGFVTSRLGLILG 186
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA--EGMQSYIDRYGETIY 221
E R+ + G G L + L+A ++S +R G+ Y
Sbjct: 187 TEAMRMVEEQVANAADIDKALRLGYGHPMGPLELADLVGLDARLNNLRSMFERSGDAAY 245
>UniRef50_Q9RZ10 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=11; Bacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Deinococcus radiodurans
Length = 347
Score = 58.4 bits (135), Expect = 2e-07
Identities = 33/120 (27%), Positives = 52/120 (43%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AVKG V E +PEN+D+K+K + L V D NTI E + +
Sbjct: 131 AVKGVDLVIEAIPENMDIKRKFYNQLGEVADPNTIFATNSSTLLPSQFMEETGRPEKFLA 190
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H N + EI+ P T V + ++IG + + +E G++LN + +L
Sbjct: 191 LHFANEIWKFNTAEIMRTPRTDDAVFDTVVQFAKDIGMVALPMYKEQAGYILNTLLVPLL 250
>UniRef50_Q9ADL9 Cluster: Beta-hydroxybutyryl-CoA dehydrogenase;
n=7; Bacteria|Rep: Beta-hydroxybutyryl-CoA dehydrogenase
- Polyangium cellulosum (Sorangium cellulosum)
Length = 293
Score = 58.4 bits (135), Expect = 2e-07
Identities = 35/119 (29%), Positives = 54/119 (45%)
Frame = -2
Query: 742 GAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHP 563
GA FV E V E D+K++V+ L+ V I K SQV+ H
Sbjct: 92 GADFVVENVTEKWDIKREVYARLEGVCRPEIIFAADTSAISITRIGSVTKRPSQVVGMHF 151
Query: 562 VNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+NP P+VE++ T PE + + E+G+ V + + GFV NR+ ++E
Sbjct: 152 MNPVPLKPMVEVIRGFHTSPETLGAAKRFLAEMGKTCV-VVEDAPGFVSNRVLMLTINE 209
>UniRef50_Q0LZ25 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Caulobacter sp. K31|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Caulobacter sp. K31
Length = 296
Score = 58.4 bits (135), Expect = 2e-07
Identities = 35/121 (28%), Positives = 63/121 (52%), Gaps = 2/121 (1%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGL--KHKSQVIVSHPVN 557
V E V E+L++K +V LD + + L + + + + +H +
Sbjct: 98 VTEAVFESLEVKGQVLAALDEACPEACVIASNTSTLPISTLGAALSPERRPRFLGAHYFS 157
Query: 556 PPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 377
P + LVE+VPA T PE T +++ IG+QP+++ +++ GF +NR+ +A+L E R
Sbjct: 158 PVSRMLLVEVVPAFETSPETVAWTTSLLKRIGKQPIAV-KDVPGFAVNRMLHAMLIEAVR 216
Query: 376 L 374
L
Sbjct: 217 L 217
>UniRef50_P76083 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=8; Enterobacteriaceae|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Escherichia coli
(strain K12)
Length = 475
Score = 58.4 bits (135), Expect = 2e-07
Identities = 42/160 (26%), Positives = 63/160 (39%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ A V E E L++KK +F L V T+ + +K+ +V
Sbjct: 81 ALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSISITAIAAEIKNPERVAG 140
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + LVE+V T EV ++ E+ G+QPV GF++NR+
Sbjct: 141 LHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVR-CHSTPGFIVNRVARPYY 199
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
E WR + +G G +G LE L
Sbjct: 200 SEAWRALEEQVAAPEVIDAALRDGAGFP---MGPLELTDL 236
>UniRef50_Q11TH9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=16;
Bacteroidetes|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Cytophaga hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 298
Score = 58.0 bits (134), Expect = 2e-07
Identities = 36/122 (29%), Positives = 55/122 (45%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A K V E VPE L++K +F+ LD TI + +VI
Sbjct: 82 AAKTVSLVVEAVPELLEIKADLFKELDMHCPPETILASNTSSISITTLASYTSRPEKVIG 141
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H +NP + LVEI+ T E ++ EI ++ + PV T + GF+ NRI ++
Sbjct: 142 MHFMNPVPVMQLVEIINGLLTSSETTRRIEEISTQLNKIPVQ-TADYPGFISNRILMPMI 200
Query: 391 DE 386
+E
Sbjct: 201 NE 202
>UniRef50_Q06BB6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Vibrio cholerae|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Vibrio cholerae
Length = 284
Score = 58.0 bits (134), Expect = 2e-07
Identities = 35/123 (28%), Positives = 57/123 (46%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
+A+K A V E V E+ D+K + + +VVDD TI + + +
Sbjct: 80 SALKSAELVIEAVSEDKDVKHDIMAKIAAVVDDTTIVASNTSSLSITELAANFRKPENFL 139
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H NP + LVE+V T + +K IG++PV + E GFV+NR+ +
Sbjct: 140 GLHFFNPAPMMSLVEVVRGLTTCESIIEKAVVFSRSIGKEPV-VVNEAPGFVVNRMLIPM 198
Query: 394 LDE 386
++E
Sbjct: 199 INE 201
>UniRef50_O29077 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Archaeoglobus fulgidus
Length = 295
Score = 58.0 bits (134), Expect = 2e-07
Identities = 37/126 (29%), Positives = 57/126 (45%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+K A F+ E V E DLKKK+F LD + TI + ++ K + I
Sbjct: 85 ALKDADFIIEAVTEKADLKKKIFAELDRICKPETIIASNTSAIMISDLATAVERKDKFIG 144
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + L+E++ T E T E+ +++G+ P+ + GF R + L
Sbjct: 145 MHWFNPAPVMRLIEVIRGALTSDETFNITVELSKKMGKIPIE-AGDGPGFFTTRFINSWL 203
Query: 391 DEVWRL 374
E RL
Sbjct: 204 VEAVRL 209
>UniRef50_Q1ATL4 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rubrobacter xylanophilus DSM 9941|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Rubrobacter
xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 287
Score = 57.6 bits (133), Expect = 3e-07
Identities = 43/193 (22%), Positives = 77/193 (39%)
Frame = -2
Query: 742 GAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHP 563
G+ V E + E + KK+ F LD+++ + + + +V +H
Sbjct: 81 GSEAVIEAIVERVGPKKEAFAALDALLPPDALLLTNTSSISITELASATGRPERVCGAHF 140
Query: 562 VNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEV 383
PP VE+V T E ++ R ++ G+ PV + +++ GF NR+ +L E
Sbjct: 141 FTPPPLREAVEVVRGEQTSDETVERVRRLLSSFGKLPVVVRKDVPGFAANRLLMPVLLEA 200
Query: 382 WRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRVSNEM 203
RL + + GLG LG + A L G+ +D + +
Sbjct: 201 ARLVEEGVASREEVDLLATRGLGFP---LGPFQLADL--IGLDVALDVISYVHEELGDPF 255
Query: 202 GPAPRMTTNKSRN 164
PR+ N+ R+
Sbjct: 256 YTPPRLLKNRVRS 268
>UniRef50_A6CP14 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Bacillus sp. SG-1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bacillus sp. SG-1
Length = 293
Score = 57.6 bits (133), Expect = 3e-07
Identities = 35/124 (28%), Positives = 56/124 (45%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+ A V E VPE ++KK VF+ +D ++ + +VI
Sbjct: 89 AVESADLVIEAVPEKTEIKKAVFEKIDEYAQESCYFATNTSTMSPTEIASFTGRPKKVIA 148
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + +PLVEIV T E + + +G++ V + E GFV +RI +
Sbjct: 149 MHFFNPVHKMPLVEIVRGLETSDETTQFAENAAKRMGKETV-VINEFPGFVTSRISALVG 207
Query: 391 DEVW 380
+E +
Sbjct: 208 NEAF 211
>UniRef50_Q5UWD9 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Haloarcula marismortui (Halobacterium marismortui)
Length = 295
Score = 57.6 bits (133), Expect = 3e-07
Identities = 37/126 (29%), Positives = 58/126 (46%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV GA V E VPE + +K + ++S VD T+ + L + + I
Sbjct: 78 AVTGADLVVEAVPEEMAIKHETLTAVESHVDPATLIASNTSSLSLTEIASVLDYPERAIG 137
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + + LVEIV A T E + RE + I + PV + + GF +R+ ++
Sbjct: 138 LHFFNPVHIMALVEIVVAEQTSAETIARAREFVNGIDKTPVEVA-DAPGFASSRLGVSLG 196
Query: 391 DEVWRL 374
E R+
Sbjct: 197 VEAMRM 202
>UniRef50_Q1QBD7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=2; Psychrobacter|Rep: 3-hydroxybutyryl-CoA
dehydrogenase precursor - Psychrobacter cryohalolentis
(strain K5)
Length = 533
Score = 57.2 bits (132), Expect = 4e-07
Identities = 41/174 (23%), Positives = 75/174 (43%), Gaps = 3/174 (1%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E + ENL++K+++F+ L+S+V TI + +H +V H NP
Sbjct: 86 VIEAIIENLEIKQQLFKQLESIVPAETILATNTSSLAVTAIASNCEHPERVAGFHFFNPV 145
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
+ +VE++P TK V + + + +G V + ++ GF++N A E ++
Sbjct: 146 PLMKIVEVIPGISTKSSVVETLTSLAKRMGHLGV-VAKDTPGFIVNHGGRAYGTEALKIL 204
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEG--MQS-YIDRYGETIYR 218
++ +G G R L+ ++ M+S Y Y E YR
Sbjct: 205 GEGVASFEDIDHILRDGAGFRMGPFELLDLTGIDVSHPVMESIYNQYYFEPRYR 258
>UniRef50_Q16836 Cluster: Hydroxyacyl-coenzyme A dehydrogenase,
mitochondrial precursor; n=40; Eukaryota|Rep:
Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial
precursor - Homo sapiens (Human)
Length = 314
Score = 57.2 bits (132), Expect = 4e-07
Identities = 35/147 (23%), Positives = 60/147 (40%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
+ V V E + ENL +K ++F+ LD ++TI + + +
Sbjct: 108 SVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTSSLQITSIANATTRQDRFA 167
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H NP + LVE++ P T + + + + +G+ PVS ++ GF++NR+
Sbjct: 168 GLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGKHPVS-CKDTPGFIVNRLLVPY 226
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLG 314
L E RL M G G
Sbjct: 227 LMEAIRLYERGDASKEDIDTAMKLGAG 253
>UniRef50_Q9XA30 Cluster: Putative 3-Hydroxyacyl-CoA dehydrogenase;
n=2; Streptomyces|Rep: Putative 3-Hydroxyacyl-CoA
dehydrogenase - Streptomyces coelicolor
Length = 504
Score = 56.8 bits (131), Expect = 5e-07
Identities = 42/153 (27%), Positives = 63/153 (41%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V E LD+K+++F+ L+ VV D+ + L+ + + H NP
Sbjct: 90 VVEAVVERLDVKQELFRALEDVVGDDCLLATNTSSLSVTAVGGALRVPGRFVGLHFFNPA 149
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
+PLVE+V T P A + E G+ PV+ + GFV+NR+ E
Sbjct: 150 PLLPLVEVVSGFATDPASATRAYETARAWGKTPVACA-DTPGFVVNRVARPFYAEALAAY 208
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
V+ E G R +GA E L
Sbjct: 209 EARAADPATVDAVLRESGGFR---MGAFELTDL 238
>UniRef50_A5VHQ1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Lactobacillus reuteri|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Lactobacillus reuteri F275
Length = 294
Score = 56.8 bits (131), Expect = 5e-07
Identities = 32/121 (26%), Positives = 57/121 (47%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
TAVK A + E +PE+L+LK++ ++ + + + TI + + +
Sbjct: 75 TAVKDADLMIEALPESLELKEQFYEEVSELAPEKTIFASNSSTFIPSQLAPYTDRPEKFL 134
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H N + +VEI+ T PEV ++ + EI PV L +E G++LN + +
Sbjct: 135 NMHFANQIWKFNVVEIMGTSQTSPEVIEEATKFAREIKMVPVILNKEQHGYILNSLLIPL 194
Query: 394 L 392
L
Sbjct: 195 L 195
>UniRef50_A4FGV2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxybutyryl-CoA dehydrogenase
- Saccharopolyspora erythraea (strain NRRL 23338)
Length = 517
Score = 56.8 bits (131), Expect = 5e-07
Identities = 34/141 (24%), Positives = 62/141 (43%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V E+LD K+++F L+ V + + L S++I H NP
Sbjct: 92 VVEAVREDLDTKRELFAGLEEVCPRHAVLATNTSSLSVTAIGAALADPSRLIGLHFFNPV 151
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
+ LVE++P T+ +++ E++ +G QPV L + GF++N + E ++
Sbjct: 152 PLMKLVEVIPGARTRQDLSADLVELVRRLGHQPV-LATDTPGFLVNHAGRGLATEALQIM 210
Query: 370 XXXXXXXXXXXXVMSEGLGMR 308
+ + LG+R
Sbjct: 211 SESAVEPSDVDRIARDVLGLR 231
>UniRef50_A3U7V8 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein; n=19; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerasefamily protein - Croceibacter
atlanticus HTCC2559
Length = 802
Score = 56.8 bits (131), Expect = 5e-07
Identities = 36/116 (31%), Positives = 54/116 (46%), Gaps = 2/116 (1%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQ--VI 575
VK ++ E V E LD+KK+VF+NL+ + T+ SEG Q
Sbjct: 99 VKDVDWIIEVVVERLDIKKQVFENLEKHRTEGTLITSNTSGIPINLMSEGRSEDFQKHFC 158
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+H NPP Y+ L EI+P P T PEV E+ + + ++ F+ NR+
Sbjct: 159 GTHFFNPPRYLELFEIIPGPKTSPEVLDFLNGYGEKFLGKTSIVAKDTPAFIGNRV 214
>UniRef50_Q12D24 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=5; Burkholderiales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 511
Score = 56.4 bits (130), Expect = 7e-07
Identities = 34/115 (29%), Positives = 56/115 (48%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A A V E + E LD+K+ +FQ L+++V + + + GL+H ++++
Sbjct: 88 AAAPARLVIEAIVEKLDVKRGLFQQLEAIVAADCVLATNTSSISVTAIANGLQHPARLVG 147
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H NP + LVE+V T P VA ++ G+ V R GF++NRI
Sbjct: 148 MHFFNPVPQMRLVEVVSGLQTDPAVAALIFDLAGVWGKVAVH-ARSTPGFIVNRI 201
>UniRef50_A1IEK7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 387
Score = 56.4 bits (130), Expect = 7e-07
Identities = 33/115 (28%), Positives = 53/115 (46%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV V E VPE +DLKKKVF ++ S + + + + +
Sbjct: 83 AVADVQVVIEAVPEIMDLKKKVFADVSSAAPAEALLASNTSTMSITEIATAVTKPERFLG 142
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H NP + LVE++ T E E+ ++IG+ PV + ++ GF++NRI
Sbjct: 143 MHFFNPVNRMKLVEVIFGEKTSAENVDLLCELSKKIGKIPVKVLKDSPGFIVNRI 197
>UniRef50_Q39NP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=54;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Burkholderia sp. (strain 383)
(Burkholderia cepacia (strain ATCC 17760/ NCIB 9086 /
R18194))
Length = 284
Score = 56.0 bits (129), Expect = 9e-07
Identities = 40/176 (22%), Positives = 70/176 (39%), Gaps = 2/176 (1%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V E EN++LK ++ + +++V I + L ++ + H
Sbjct: 83 ADIVIEAATENVELKGRILKQIEAVARAEAIIATNTSSISITALAAPLADPARFVGMHFF 142
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
NP +PLVEI+ T A RE+ E + P+ + R GFV+NRI +++E +
Sbjct: 143 NPVPLMPLVEIIRGLQTSDATASAVRELTERFDKSPIGV-RNSPGFVVNRILVPMINEAF 201
Query: 379 RLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA--EGMQSYIDRYGETIYR 218
+ M G L + L+ M ++ +G+ YR
Sbjct: 202 FVLAEGIASAEEIDAGMKLGANHPIGPLALADLVGLDVCLAVMDVFVKDFGDPKYR 257
>UniRef50_Q0SEM1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 286
Score = 56.0 bits (129), Expect = 9e-07
Identities = 32/116 (27%), Positives = 55/116 (47%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
T ++ A V ECVPE +DLK+KVF LD V + + ++ +V+
Sbjct: 81 TDLRDAAVVIECVPERIDLKEKVFAELDRVCAPDALLASCTSGIPVDRLADTTTRPERVV 140
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H +NP VE+V P T P+ + ++ + + + + + GF+LNR+
Sbjct: 141 GLHFMNPAPLKDTVEVVRGPRTSPQSLDRALALLASLNKTGI-VVGDGPGFLLNRV 195
>UniRef50_A0QZR0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 296
Score = 55.6 bits (128), Expect = 1e-06
Identities = 32/107 (29%), Positives = 52/107 (48%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V E+L LKK+ F LD +V T+ + G + + +V+ +H NP
Sbjct: 92 VVEAVFEDLSLKKETFGRLDDIVPPTTLFHTNTSTLSVTGIASGSRLRERVVGTHYCNPA 151
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 410
+ LVE+ T K T E + +G+ V +T++ GF++NR
Sbjct: 152 PLMKLVEVANGRHTADWAHKATLEFLASLGKTSV-VTKDRPGFIVNR 197
>UniRef50_Q67SZ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Symbiobacterium thermophilum|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Symbiobacterium thermophilum
Length = 517
Score = 55.2 bits (127), Expect = 2e-06
Identities = 33/122 (27%), Positives = 57/122 (46%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A FV E PE+L+LK+++F+ LD + ++ + +V+ H
Sbjct: 81 ADFVIEAAPEDLELKRRLFERLDRLCREDVVLATNTSSLSVTQIGALAGRADRVVGMHFF 140
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
NP + LVE+V + + T + E +G+ PV + R+ GF++NR+ E
Sbjct: 141 NPVPAMRLVEVVGGDASGEAALQATVSLAEAMGKVPVRV-RDTPGFIVNRVARPFTGEAL 199
Query: 379 RL 374
RL
Sbjct: 200 RL 201
>UniRef50_Q2SGN8 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 283
Score = 55.2 bits (127), Expect = 2e-06
Identities = 39/160 (24%), Positives = 69/160 (43%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ FV E +PEN++LK+ ++ + + N + K +QVI
Sbjct: 80 AISDCAFVVENIPENIELKQALYTRMAEFIAPNAVLAANTSCIPITKLGSFHKTSAQVIG 139
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H +NP Y VE++ T + + E++ +G++ V + ++ GFV NRI + +
Sbjct: 140 VHFMNPVYLKHTVEVILGLNTSEQTKDRCLEMLAMLGKKAV-VVKDGPGFVSNRISHLFM 198
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
+E + E G + +G LETA L
Sbjct: 199 NEAAFAIQDGIAQPADVDAIFKECFGHK---MGPLETADL 235
>UniRef50_Q47M90 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
root|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Thermobifida fusca (strain YX)
Length = 398
Score = 54.8 bits (126), Expect = 2e-06
Identities = 32/106 (30%), Positives = 51/106 (48%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E VPE LD+K+ VF +LD ++ I + +VI H NP
Sbjct: 90 EAVPERLDIKRSVFADLDRILPPAAILATNTSSLSVTEIAALTSRPGKVIGLHFFNPAPV 149
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+ LVEIV T+P V + +++ +G+ PV++ + GFV N +
Sbjct: 150 MRLVEIVTTVVTEPHVRETATQVVTRLGKTPVAV-GDRAGFVANAL 194
>UniRef50_Q68WH7 Cluster: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)]; n=20;
Rickettsia|Rep: Putative fatty acid oxidation complex
trifunctional enzyme [Includes: 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35); Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase (EC 4.2.1.17) (EC 5.3.3.8)] - Rickettsia typhi
Length = 720
Score = 54.8 bits (126), Expect = 2e-06
Identities = 33/124 (26%), Positives = 60/124 (48%), Gaps = 2/124 (1%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVI 575
+K V E + E LD+K +++ + + ++TI E L + KS+ I
Sbjct: 84 IKECNLVIEVIVEKLDIKHQLYNKIIPYLKEDTIIASNTSTLPLKKLKENLPNNIKSRFI 143
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
++H NPP Y+ LVE++ K EV +K + +I + + + GF+ NR+ +
Sbjct: 144 ITHFFNPPRYMELVELIIDNTIKDEVIEKISVFLTKILGKTIIKCNDTPGFIANRVGCFL 203
Query: 394 LDEV 383
L+ V
Sbjct: 204 LELV 207
>UniRef50_Q8KUG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=8;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Actinosynnema pretiosum subsp. auranticum
Length = 341
Score = 54.4 bits (125), Expect = 3e-06
Identities = 36/155 (23%), Positives = 64/155 (41%)
Frame = -2
Query: 736 IFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVN 557
+ V E V E+ + K K + + V T + L ++ +H +N
Sbjct: 133 VAVVEAVTEDAETKAKALTGVCATVPPGTPLVSNTSSIPMGELAPALPRPGDLVGAHFMN 192
Query: 556 PPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 377
PPY +P VE+ P T ++ +G+ PV + + GFV +R+ + ++++ R
Sbjct: 193 PPYLIPAVEVARGPLTSDAAFAGLTALLARLGRAPVQV-GDAPGFVTSRLLHPMINDAAR 251
Query: 376 LXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
+ +M + LG R G L TA L
Sbjct: 252 VVESGTADAAAVDALMRDCLGHRE---GPLRTADL 283
>UniRef50_Q4J598 Cluster: 3-hydroxyacyl-CoA dehydrogenase, NAD
binding domain; n=2; Azotobacter vinelandii|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain -
Azotobacter vinelandii AvOP
Length = 208
Score = 54.4 bits (125), Expect = 3e-06
Identities = 24/92 (26%), Positives = 48/92 (52%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
V G + E +PE ++LK+ ++ L+ +VD + +EG++H +++++
Sbjct: 80 VAGVRLLIETLPERIELKRALYAELERIVDAEAVIASDTGGLSPERLAEGMRHPGRLLIA 139
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIM 473
H +PP+ VPLV +V T+ E R ++
Sbjct: 140 HFRSPPHRVPLVAVVAGRQTRSEHLAYVRTLL 171
>UniRef50_A1SXV8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Psychromonas|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychromonas ingrahamii
(strain 37)
Length = 724
Score = 54.4 bits (125), Expect = 3e-06
Identities = 31/115 (26%), Positives = 54/115 (46%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V ENL++KK V + +++ + I + L+ I H NP
Sbjct: 407 VVEAVSENLEVKKTVLEEVEAQLSKQAILASNTSSLSITEMAVNLQRPENFIGMHFFNPV 466
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+PLVEI+P T + ++ ++ G+ P+ + GF++NRI + L+E
Sbjct: 467 NRMPLVEIIPGEKTSQQTIVTLVKLAKKAGKTPI-VVANCAGFLVNRILISFLNE 520
>UniRef50_A7D676 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Halorubrum lacusprofundi ATCC
49239|Rep: 3-hydroxyacyl-CoA dehydrogenase, NAD-binding
- Halorubrum lacusprofundi ATCC 49239
Length = 676
Score = 54.4 bits (125), Expect = 3e-06
Identities = 28/115 (24%), Positives = 51/115 (44%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E VPE + +KK V+ + + + SE + H NPP
Sbjct: 103 VVEVVPEKMAIKKDVYDEVVEYAPEEAVFVTNTSSLSITELSEVTDRPERFCGMHFFNPP 162
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+ LVE++ T + + + E +G+ PV + ++ GF++NRI +++E
Sbjct: 163 VRMDLVEVISGKHTSEDTLELIEGLAESMGKTPVRVRKDSPGFIVNRILVPLMNE 217
>UniRef50_A4RUY4 Cluster: Predicted protein; n=5; cellular
organisms|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 722
Score = 54.0 bits (124), Expect = 4e-06
Identities = 40/171 (23%), Positives = 73/171 (42%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V ENL LK+K+F L+ + + I + +K+ +++ +H +P
Sbjct: 387 VIEAVIENLPLKQKIFCELERICKPDCILSTNTSTIDITKIAAKMKNPERIVGAHFFSPA 446
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
+ + L EI+ T ++ T + ++I + PV + GF +NRI + L
Sbjct: 447 HVMQLFEIIRTDATPAQILVDTLGLSKQIKKTPV-VVGNCTGFAVNRIFFPYTMSATVLV 505
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYR 218
+M G+ M LG L + Q++ID + + +YR
Sbjct: 506 DIGCDPYAIDRAIMMFGMPMGPFRLGDLVGHDVGVHVGQNFIDDFPDRVYR 556
>UniRef50_P45364 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=13;
Clostridia|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Clostridium difficile
Length = 281
Score = 54.0 bits (124), Expect = 4e-06
Identities = 33/121 (27%), Positives = 57/121 (47%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+K + E E++++KK VF+ LD + ++TI + K +VI
Sbjct: 77 LKDMDLIIEASVEDMNIKKDVFKLLDELCKEDTILATNTSSLSITEIASSTKRPDKVIGM 136
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H NP + LVE++ T E+ + I + PV ++ E GFV+NRI +++
Sbjct: 137 HFFNPVPMMKLVEVISGQLTSKVTFDTVFELSKSINKVPVDVS-ESPGFVVNRILIPMIN 195
Query: 388 E 386
E
Sbjct: 196 E 196
>UniRef50_Q0RL76 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Frankia alni ACN14a|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Frankia alni
(strain ACN14a)
Length = 234
Score = 53.6 bits (123), Expect = 5e-06
Identities = 36/130 (27%), Positives = 58/130 (44%), Gaps = 3/130 (2%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
+AV GA V E VPE+L LK +VF+ LD V + + ++V+
Sbjct: 69 SAVAGAAVVIEAVPEDLALKVRVFRELDRVAAAGAVLATNSSGFPVGALAAATDRPTRVL 128
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREID---GFVLNRIQ 404
H +P + EIV T P+ + +G+ PV + R+ G+V NR+
Sbjct: 129 GWHWSSPAQIMRFAEIVVTEHTDPDAVATVTRLAHGLGKNPV-VVRDAPMAWGYVANRVY 187
Query: 403 YAILDEVWRL 374
+A + E R+
Sbjct: 188 WAAVAEARRI 197
>UniRef50_A3M4C7 Cluster: PaaC; n=1; Acinetobacter baumannii ATCC
17978|Rep: PaaC - Acinetobacter baumannii (strain ATCC
17978 / NCDC KC 755)
Length = 435
Score = 53.6 bits (123), Expect = 5e-06
Identities = 36/125 (28%), Positives = 57/125 (45%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A++ A V E V E ++K+ +F+ L + TI S G+ H +V+
Sbjct: 7 ALRDADLVIEAVVEKKEVKQSLFKQLAEICSAQTIFASNTSSISVTAISAGIAHPERVVG 66
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + LVEIV T + + +M + + PV LT+ GF++NRI
Sbjct: 67 LHFFNPAPVMKLVEIVQGLKTPNSLCLALKNLMLDWKKIPV-LTKSTPGFIVNRIARPFY 125
Query: 391 DEVWR 377
E +R
Sbjct: 126 AEGFR 130
>UniRef50_Q5KBI5 Cluster: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative; n=1; Filobasidiella
neoformans|Rep: Short chain 3-hydroxyacyl-CoA
dehydrogenase, putative - Cryptococcus neoformans
(Filobasidiella neoformans)
Length = 342
Score = 53.6 bits (123), Expect = 5e-06
Identities = 38/148 (25%), Positives = 62/148 (41%), Gaps = 2/148 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+ A V E + E++ +K+ +F LD + I +E + Q
Sbjct: 114 AVENADLVVEAIIESIKVKRDLFGFLDGKAKSDCIFATNTSSLSVTEIAEACSPERQAKF 173
Query: 571 S--HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYA 398
+ H NP + LVEI+ P T E + RE+ ++G+ PV+ + GF++NR+
Sbjct: 174 AGLHFFNPVPAMKLVEIIRTPQTSQETYETLREVTLQMGKSPVT-CNDTPGFIVNRLLVP 232
Query: 397 ILDEVWRLXXXXXXXXXXXXXVMSEGLG 314
L E R+ M G G
Sbjct: 233 YLLEAIRMIERGDATAEDIDTAMELGAG 260
>UniRef50_Q84T13 Cluster: L-3-hydroxyacyl-CoA dehydrogenase subunit
precursor; n=1; Euglena gracilis|Rep:
L-3-hydroxyacyl-CoA dehydrogenase subunit precursor -
Euglena gracilis
Length = 320
Score = 53.2 bits (122), Expect = 7e-06
Identities = 38/147 (25%), Positives = 59/147 (40%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ V E + E+L++KKK F +L V N I E S +
Sbjct: 106 ALSSCDLVIESIIEDLNIKKKFFADLGKVAGANAILASNTSSFPITQLGEASGRTSNFLG 165
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + LVE++ TK +V K + IG++PV+ + GF++NR+ L
Sbjct: 166 LHFFNPVQMMKLVEVIKTKDTKEDVYKLGFAFSKSIGKEPVA-CGDTPGFIVNRLLVPFL 224
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGM 311
+ + M G GM
Sbjct: 225 AQGLLMLDRGVASVQDIDVAMMYGAGM 251
>UniRef50_Q0SCS0 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 284
Score = 52.8 bits (121), Expect = 9e-06
Identities = 43/153 (28%), Positives = 63/153 (41%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E VPE +DLK V ++ V T+ L +++I H NP
Sbjct: 88 VVEAVPELVDLKLSVLSLVEKTVSPTTVIASNTSSISIAELGSALGDPARLIGMHFFNPV 147
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
LVEIV AP T V +K RE + ++G+ V L + GF +R+ + E R+
Sbjct: 148 PASSLVEIVRAPATDAGVVEKVREWVAQLGKTEV-LVNDSPGFATSRLGVCLGLEAIRML 206
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
M LG R+ +G L + L
Sbjct: 207 EEGVADAESIDRAME--LGYRHP-MGPLRSTDL 236
>UniRef50_A6WDS7 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=1; Kineococcus radiotolerans
SRS30216|Rep: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding - Kineococcus radiotolerans SRS30216
Length = 681
Score = 52.8 bits (121), Expect = 9e-06
Identities = 46/177 (25%), Positives = 76/177 (42%), Gaps = 4/177 (2%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
+A+ A FV E V E L +K+ V + L+ ++ + + + L+H + +
Sbjct: 394 SALADADFVVEAVFEELAVKQDVLRELEPLLRPDAVIATNTSSLSVTAMASVLEHPQRFV 453
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H NP +PLVE+V P T E + T + ++ L ++ FV+NRI +
Sbjct: 454 GFHFFNPVAVLPLVEVVRTPET-DEASLATAFAVGARLKKTCVLVQDAPAFVVNRISTRM 512
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGM---RYA-FLGALETAHLNAEGMQSYIDRY 236
DEV R + GL M R A F+G H++ ++ DRY
Sbjct: 513 FDEVVRALDAGTPLLEVERSLDPLGLPMSPFRLASFVGPAVMLHVHETLAAAFPDRY 569
>UniRef50_A2QXC7 Cluster: Contig An11c0270, complete genome.
precursor; n=6; Pezizomycotina|Rep: Contig An11c0270,
complete genome. precursor - Aspergillus niger
Length = 599
Score = 52.8 bits (121), Expect = 9e-06
Identities = 37/125 (29%), Positives = 56/125 (44%), Gaps = 1/125 (0%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLK-HKSQV 578
+ V A V E VPE+L +K V LD + + I E + H+ +
Sbjct: 83 STVSDAWLVIEAVPEHLQMKIDVMGELDKLAPVDCILASNSSSFKSRFMLEKVGGHRRPL 142
Query: 577 IVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYA 398
+ + P +VE++ T PEV ++E++G PV+ RE GFV NR+ A
Sbjct: 143 VCNMHFYMPPEKRVVELMTDGETWPEVFPFLTRVLEDVGMVPVTARRESTGFVFNRLWAA 202
Query: 397 ILDEV 383
I EV
Sbjct: 203 IKREV 207
>UniRef50_A0PRD1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase FadB3;
n=1; Mycobacterium ulcerans Agy99|Rep:
3-hydroxybutyryl-CoA dehydrogenase FadB3 - Mycobacterium
ulcerans (strain Agy99)
Length = 294
Score = 52.4 bits (120), Expect = 1e-05
Identities = 31/123 (25%), Positives = 56/123 (45%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
TA++GA E VPE L++K ++ +D +TI ++ ++ K+++
Sbjct: 84 TALEGAWLAVESVPEKLEIKTALWGQIDQAAPPDTIFATNSSSFPSRLMADNVRDKTRLC 143
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
+H PP + L +++ T + ++ E G P RE GF+ NR+ AI
Sbjct: 144 NTHFYMPPQFNAL-DLMSDGETDRGLLDTLLTVLPEFGVHPFEARRECTGFIFNRVWAAI 202
Query: 394 LDE 386
E
Sbjct: 203 KRE 205
>UniRef50_O44608 Cluster: Hydroxy-acyl-coa dehydrogenase protein 1;
n=2; Caenorhabditis|Rep: Hydroxy-acyl-coa dehydrogenase
protein 1 - Caenorhabditis elegans
Length = 299
Score = 52.4 bits (120), Expect = 1e-05
Identities = 43/178 (24%), Positives = 72/178 (40%), Gaps = 1/178 (0%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
+A + A E V ENLDLK +FQ + N + +++ +
Sbjct: 94 SAAEDAAMAIEAVAENLDLKLDIFQTIQKTCPQNCMLITNTSSLKLSQMLPVIQNPALFA 153
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H NP + LVE+V T PE +EI + PV+ ++ GF++NR+
Sbjct: 154 GLHFFNPVPVMKLVEVVSTDETSPETTNFLFNFCKEIKKLPVA-AKDTPGFIVNRLLIPY 212
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETA-HLNAEGMQSYIDRYGETI 224
L + R+ M G Y +G +E ++ + +QS + + ETI
Sbjct: 213 LMDSIRMLERGDATKEDIDTAMR--FGTSYP-MGPIELCDYVGLDVLQSTLKIFRETI 267
>UniRef50_O69856 Cluster: Fatty acid oxidation complex
alpha-subunit; n=6; Actinobacteria (class)|Rep: Fatty
acid oxidation complex alpha-subunit - Streptomyces
coelicolor
Length = 709
Score = 52.0 bits (119), Expect = 2e-05
Identities = 33/119 (27%), Positives = 55/119 (46%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A FV E V E + +K+KVF +++V + I + LKH +V+ H
Sbjct: 420 ADFVIEAVFEEMGVKQKVFAEVEAVAPAHAILATNTSSLSVSEMASKLKHPERVVGFHFF 479
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEV 383
NP +PL+EIV T + +++ + V L ++ FV+NRI + E+
Sbjct: 480 NPVAILPLLEIVRGEQTDEAALATAFGVAKKLKKTAV-LVKDAPAFVVNRILTRFMGEI 537
>UniRef50_A6GBG1 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=1; Plesiocystis
pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Plesiocystis pacifica SIR-1
Length = 789
Score = 52.0 bits (119), Expect = 2e-05
Identities = 30/117 (25%), Positives = 57/117 (48%), Gaps = 2/117 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQV 578
AV + V E + E LD+K+ VF+ + + + TI +E L + +
Sbjct: 75 AVAESDIVIEAIIERLDIKQTVFKKVAAAAKETTILASNTSGIPIADIAEALDEGARERF 134
Query: 577 IVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+ H NPP ++ L+E++P+ +T + + + +E+ + V L R+ F+ NRI
Sbjct: 135 LGLHFFNPPRWMHLLEVIPSKYTAKKYVDEVAKFSDEVLGKGVVLCRDTPNFIGNRI 191
>UniRef50_A1SSP5 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Psychromonas ingrahamii 37|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Psychromonas ingrahamii (strain 37)
Length = 511
Score = 52.0 bits (119), Expect = 2e-05
Identities = 29/114 (25%), Positives = 54/114 (47%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+ A V E + ENL++K+ +F+ L+++ + I + LK + I
Sbjct: 83 IASANLVIEAIVENLEIKQGLFKELETICSADCILASNTSSISITAIASALKSPERFIGL 142
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H NP + LVE++ T +A+ ++ G++ V L I GF++NR+
Sbjct: 143 HFFNPAPVMKLVEVIQGVATADNIAETAQQWARSCGKKSV-LACSIPGFIVNRV 195
>UniRef50_O29090 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 312
Score = 52.0 bits (119), Expect = 2e-05
Identities = 41/170 (24%), Positives = 74/170 (43%), Gaps = 2/170 (1%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNP 554
F+ E + E L K ++F+ ++ + + + + L + ++ + H NP
Sbjct: 81 FIVEAIVERLRDKIELFRKIEEI-NSPAVLATNTSSFMPSEIARHLANPERLTLFHFSNP 139
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
P +PLVE V E ++ E+ + IG++PV L +E G VLNR+ A V
Sbjct: 140 PILMPLVE-VGGEIVSDETVERAVEMAKSIGKEPVVLRKECRGHVLNRMLAAAGVAVGYC 198
Query: 373 XXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA--EGMQSYIDRYGE 230
LGMRY F ++ L+ + ++S+ + YG+
Sbjct: 199 LLYSRPEEIDAAL---RNLGMRYGFFETIDLIGLDVAKDVLESFREYYGD 245
>UniRef50_Q1IIH2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=5;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Acidobacteria bacterium (strain
Ellin345)
Length = 282
Score = 51.2 bits (117), Expect = 3e-05
Identities = 30/115 (26%), Positives = 54/115 (46%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E E ++K ++F++LDS+ + I + K +VI H NP
Sbjct: 86 VVEAASERFEIKAELFRDLDSICRPDVILATNTSSISITKIAAVTKRPDKVIGMHFFNPV 145
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+ LVE++ T E + + + E++ + PV + + GFV NR+ +L+E
Sbjct: 146 PVMKLVEVIRGLATSDETYQAVKVLSEKLEKTPVEV-NDAPGFVSNRVLMPLLNE 199
>UniRef50_Q8FUX6 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=4; Brucella|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 501
Score = 50.8 bits (116), Expect = 4e-05
Identities = 40/184 (21%), Positives = 73/184 (39%), Gaps = 5/184 (2%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+ A V E + ENL +KK + L++++ + + K+ ++
Sbjct: 83 IVSADLVVEAIVENLTVKKDLVAALEAILPRQAVIATNTSSLSVTAIAASAKYPERIAGF 142
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H NP + +VE++ T V +E+ +G +PV+ T + GF++N A
Sbjct: 143 HFFNPVPLMRVVEVIKGALTGDAVVDALKELAVRVGHRPVNAT-DTPGFIINHAGRAYGT 201
Query: 388 EVWRLXXXXXXXXXXXXXVMSEGLGMRYA-----FLGALETAHLNAEGMQSYIDRYGETI 224
E + ++ + G R L L+ +HL E + Y Y E+
Sbjct: 202 EALAMVKEGVADFATIDTILRDAAGFRMGPFELFDLTGLDVSHLVME--EVYHQYYEESR 259
Query: 223 YRVS 212
YR S
Sbjct: 260 YRPS 263
>UniRef50_Q83DW6 Cluster: Fatty oxidation complex, alpha subunit;
n=9; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - Coxiella burnetii
Length = 642
Score = 50.8 bits (116), Expect = 4e-05
Identities = 33/126 (26%), Positives = 60/126 (47%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
T VK A + E V E++ +K++V ++ + I S LK+ +++
Sbjct: 344 TGVKKADLIIEAVFEDIKVKQEVLSAIEPQLKPEAILATNTSSLSLDELSSVLKNPERLV 403
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H NP +PLVE+ + T ++A+K + I + P++++ GF++NR A
Sbjct: 404 AIHFFNPVAKLPLVEVASSQQTSADIAEKALAFVGAIDKLPLAVSSS-PGFLVNRALMAY 462
Query: 394 LDEVWR 377
L E R
Sbjct: 463 LLEANR 468
>UniRef50_Q39D25 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=48;
Burkholderiales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Burkholderia sp. (strain 383) (Burkholderia cepacia
(strain ATCC 17760/ NCIB 9086 / R18194))
Length = 849
Score = 50.8 bits (116), Expect = 4e-05
Identities = 29/110 (26%), Positives = 49/110 (44%), Gaps = 2/110 (1%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVIVSHPVN 557
V E + E +D K +++ + + N I SEG KS+ H N
Sbjct: 128 VIEAIAERMDWKHDLYKKVAPHIAPNAIFATNTSGLSITKLSEGFSDELKSRFCGVHFFN 187
Query: 556 PPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
PP Y+ LVE++P T+PE+ + + I + V ++ F+ NR+
Sbjct: 188 PPRYMHLVELIPTAHTRPEILDQLETFLTSIVGKGVVRAKDTPNFIANRV 237
>UniRef50_Q2J6P6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=10;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Frankia sp. (strain CcI3)
Length = 624
Score = 50.8 bits (116), Expect = 4e-05
Identities = 36/162 (22%), Positives = 63/162 (38%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV V E + E + K+ +F LD + T+ + G +V+
Sbjct: 114 AVADCELVIEAIDERMSAKQALFARLDEICPPATVFLTNTSSLSVTELAAGTARPERVLG 173
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+H NP + LVE+V T P V ++ ++G+ V + + GF++N + + L
Sbjct: 174 THWFNPAPVMRLVEVVRTVVTDPTVLAGVIGLVNDVGKTAV-VAEDRAGFIVNALLFGYL 232
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNA 266
+ R+ M G G L L+ L+A
Sbjct: 233 NNAVRMLEARYAAREDIDAAMRLGCGHPMGPLALLDLIGLDA 274
Score = 48.4 bits (110), Expect = 2e-04
Identities = 30/137 (21%), Positives = 55/137 (40%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E V E+L +K+++F +LD + + + VI H NP
Sbjct: 427 EAVVEDLAVKRELFADLDKIAAPGAVLATTTSSLPVIECAMATSRPRDVIGMHWFNPAPA 486
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXX 365
+ L+E+VP T +V + G+ PV L + GF++N + + L++ ++
Sbjct: 487 MKLIEVVPTVLTGDDVTATVLALSRAAGRHPV-LCADRAGFIVNALLFPYLNDAVKMLQA 545
Query: 364 XXXXXXXXXXVMSEGLG 314
M+ G G
Sbjct: 546 HYATIEDVDTAMTVGCG 562
>UniRef50_A3YFA8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Marinomonas sp. MED121|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Marinomonas sp. MED121
Length = 545
Score = 50.8 bits (116), Expect = 4e-05
Identities = 30/125 (24%), Positives = 57/125 (45%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+K A + E + E L++K+ +F+ L+ + I + LK+ + +
Sbjct: 91 LKSADLIIEAIVETLEIKQSLFRALELICKPECILASNTSSISITAIASCLKYPERFLGL 150
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H NP +PLVE++ + +AK+ + G+ PV T+ GF++NR+
Sbjct: 151 HFFNPAPVMPLVEVISGLASDQLIAKQLYDTCLLWGKTPVK-TKSTPGFIVNRVARPFYA 209
Query: 388 EVWRL 374
E R+
Sbjct: 210 EALRI 214
>UniRef50_A1B712 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 765
Score = 50.8 bits (116), Expect = 4e-05
Identities = 30/114 (26%), Positives = 55/114 (48%), Gaps = 3/114 (2%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLK--HKSQVIVSH 566
A ++ E +PE L LK+ +++ L + +I G+ + +++H
Sbjct: 78 ADWIVEALPERLALKQSLYRQLQGIRKPGSILSSNTSTIPLAALVGGMAGDFAADFLITH 137
Query: 565 PVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEE-IGQQPVSLTREIDGFVLNRI 407
NPP + L+E+V P T+PE+ + + +G+ VS R+ GF+ NRI
Sbjct: 138 FFNPPRRMRLLELVAGPATRPEIVALITDFCDRRLGKDVVSC-RDTPGFIANRI 190
>UniRef50_A0IJE2 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=5; Gammaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Serratia proteamaculans 568
Length = 506
Score = 50.8 bits (116), Expect = 4e-05
Identities = 32/118 (27%), Positives = 52/118 (44%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V E L +K+ +F+ L+++ T+ + L+H ++ H NP
Sbjct: 90 VIEAVAEKLAIKQSLFRELEALCSPATLFASNTSSLSITAIAGALQHPQRLAGLHFFNPA 149
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 377
+ LVEIV T E + + + G+Q V L R GF++NR+ E R
Sbjct: 150 PLMKLVEIVSGLDTSTETVATLQRLTRQWGKQSV-LCRSTPGFIVNRVARPFYAEALR 206
>UniRef50_Q39TJ4 Cluster: 3-hydroxyacyl-CoA dehydrogenase-like; n=1;
Geobacter metallireducens GS-15|Rep: 3-hydroxyacyl-CoA
dehydrogenase-like - Geobacter metallireducens (strain
GS-15 / ATCC 53774 / DSM 7210)
Length = 290
Score = 50.4 bits (115), Expect = 5e-05
Identities = 38/142 (26%), Positives = 58/142 (40%), Gaps = 3/142 (2%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXX---XXXXXXSEGLKHKSQVIVSHPV 560
V E + E+LD+K + F+ L+ V + I + KS+ + H
Sbjct: 89 VIEAIFEDLDVKSQNFRQLEEVCKPSCIIASNTSSLPITKLGACFSSAERKSRFVGMHFF 148
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
+P + LVE+V T E + IG++P+ + + GFV+NRI AI DE
Sbjct: 149 SPAAIMKLVEVVNGEDTSAETVETACAFCTSIGKEPIKV-NDCAGFVVNRILGAINDEAI 207
Query: 379 RLXXXXXXXXXXXXXVMSEGLG 314
RL GLG
Sbjct: 208 RLLEENVASAADIDKACQLGLG 229
>UniRef50_Q6KYW3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Picrophilus torridus|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Picrophilus torridus
Length = 273
Score = 50.4 bits (115), Expect = 5e-05
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 2/115 (1%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNL--DSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
E V E +D+K+ V + DS++ NT S+ +++ + I H NPP
Sbjct: 82 EAVLERIDVKRDVLSRIRSDSIIATNT------SSISITYLSKFVRNPEKFIGMHFFNPP 135
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+ L+EIV T E K+ +I +G+ PV + + GFV NR+ A+L E
Sbjct: 136 PIMSLIEIVRGNSTSDETTKRIVDISRSLGKTPVEV-NDFPGFVSNRVLMAMLRE 189
>UniRef50_Q5P607 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=2; Proteobacteria|Rep: Fusion
of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 671
Score = 50.0 bits (114), Expect = 6e-05
Identities = 29/114 (25%), Positives = 57/114 (50%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+ A +V E EN+ LK+++F ++++VV + + L+H + V+
Sbjct: 97 IADADWVLEAATENIALKRRIFADVEAVVRPDALITSNTSSLPAAQIFAELRHPERATVT 156
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H P + P+VE+V +P V + R + G+ P+ +T ++ F+L+RI
Sbjct: 157 HFFAPAWRNPVVEVVRWEKAEPAVVEYLRWLFCSTGKVPL-VTDDVVCFMLDRI 209
>UniRef50_Q3JZL6 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=7; Streptococcus agalactiae|Rep: 3-hydroxyacyl-CoA
dehydrogenase, putative - Streptococcus agalactiae
serotype Ia
Length = 377
Score = 50.0 bits (114), Expect = 6e-05
Identities = 32/126 (25%), Positives = 53/126 (42%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A V E VPE + +K+ ++ L V TI ++ + +
Sbjct: 168 AVSDADLVIEAVPETVSIKEDFYKQLAKVAPSKTIFATNSSTLVPSQFADITGRPDKFLA 227
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H N + +VEI+ T EV K+ ++IG P+ + +E G++LN I L
Sbjct: 228 MHFANNIWQNNIVEIMGHKGTDDEVIKEALTFSKDIGMVPLHIHKEQPGYILNSILVPFL 287
Query: 391 DEVWRL 374
+ L
Sbjct: 288 ESALAL 293
>UniRef50_Q14G85 Cluster: Fusion product of 3-hydroxacyl-CoA
dehydrogenase and acyl-CoA-binding protein; n=11;
Francisella tularensis|Rep: Fusion product of
3-hydroxacyl-CoA dehydrogenase and acyl-CoA-binding
protein - Francisella tularensis subsp. tularensis
(strain FSC 198)
Length = 898
Score = 50.0 bits (114), Expect = 6e-05
Identities = 27/108 (25%), Positives = 49/108 (45%), Gaps = 2/108 (1%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS--HPVNPP 551
E V E +D+K+ ++ + S + +N I ++ L +V H NPP
Sbjct: 203 EAVAERIDIKESLYTKISSHIKENAILASNTSGLSITKLAQVLPENLKVNFCGVHFFNPP 262
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
Y+PLVE++P T E+ K + E + + ++ F+ NR+
Sbjct: 263 RYMPLVELIPHADTNSEILDKLETFLVEKLGKSIIRAKDTPNFIANRL 310
>UniRef50_P45856 Cluster: Probable 3-hydroxybutyryl-CoA
dehydrogenase; n=65; Bacteria|Rep: Probable
3-hydroxybutyryl-CoA dehydrogenase - Bacillus subtilis
Length = 287
Score = 50.0 bits (114), Expect = 6e-05
Identities = 31/118 (26%), Positives = 54/118 (45%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V E + EN+ K ++F+ LD + +TI + +VI H +
Sbjct: 83 ADIVIEAIAENMAAKTEMFKTLDRICPPHTILASNTSSLPITEIAAVTNRPQRVIGMHFM 142
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
NP + LVE++ T E A + E++G+ V + + GFV NR+ +++E
Sbjct: 143 NPVPVMKLVEVIRGLATSEETALDVMALAEKMGKTAVEV-NDFPGFVSNRVLLPMINE 199
>UniRef50_Q8YB80 Cluster: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE; n=32;
Proteobacteria|Rep: 3-HYDROXYBUTYRYL-COA DEHYDROGENASE -
Brucella melitensis
Length = 565
Score = 49.6 bits (113), Expect = 8e-05
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 3/176 (1%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E + E LD K+ +F L++VV N I + +H +V H NP
Sbjct: 128 VVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSLSVTSIARVCRHPERVAGFHFFNPV 187
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
+ +VE++ T P V + + +G + +++ GF++N A E ++
Sbjct: 188 PLMKVVEVIDGLTTDPAVGDALLVLAKRMGHHGIR-AKDMPGFIINHAGRAYGTEALKIL 246
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEG--MQS-YIDRYGETIYRVS 212
++ E G R L + L+ M+S Y Y E YR S
Sbjct: 247 GECVAPRGDIDRILRESAGFRMGPLELFDLTGLDVSHPVMESIYNQFYQEPRYRPS 302
>UniRef50_Q8FX64 Cluster: 3-hydroxyacyl-CoA dehydrogenase family
protein; n=10; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase family protein - Brucella suis
Length = 509
Score = 49.6 bits (113), Expect = 8e-05
Identities = 41/176 (23%), Positives = 69/176 (39%), Gaps = 3/176 (1%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E + E LD K+ +F L++VV N I + +H +V H NP
Sbjct: 88 VVEAIVEKLDAKQALFLELEAVVSGNCILATNTSSLSVTSIARVCRHPERVAGFHFFNPV 147
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
+ +VE++ T P V + + +G + +++ GF++N A E ++
Sbjct: 148 PLMKVVEVIDGLTTDPAVGDALLVLAKRMGHHGIR-AKDMPGFIINHAGRAYGTEALKIF 206
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEG--MQS-YIDRYGETIYRVS 212
++ E G R L + L+ M+S Y Y E YR S
Sbjct: 207 GECVAPRGDIDRILRESAGFRMGPLELFDLTGLDVSHPVMESIYNQFYQEPRYRPS 262
>UniRef50_Q2S2J8 Cluster: Fatty oxidation complex, alpha subunit;
n=2; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Salinibacter ruber (strain DSM 13855)
Length = 719
Score = 49.6 bits (113), Expect = 8e-05
Identities = 38/146 (26%), Positives = 60/146 (41%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
++ A V E VPE+L +K V +++VVD +T+ +EG+ S+V+
Sbjct: 395 LQAADVVIEAVPEDLSIKHAVLSEVETVVDADTVLASNTSALPISTIAEGVDDPSRVLGM 454
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H +P +PL+EIV T E A T + V + + GF RI ++
Sbjct: 455 HYFSPVPDIPLLEIVVTEETSDE-ALATAYAAGLAQDKTVIVVNDGPGFYTTRILALYMN 513
Query: 388 EVWRLXXXXXXXXXXXXXVMSEGLGM 311
E L +M G M
Sbjct: 514 EALLLFEAGAEIEAVDEAMMDAGFPM 539
>UniRef50_Q7RZ80 Cluster: Putative uncharacterized protein
NCU04393.1; n=2; Sordariales|Rep: Putative
uncharacterized protein NCU04393.1 - Neurospora crassa
Length = 420
Score = 49.6 bits (113), Expect = 8e-05
Identities = 32/118 (27%), Positives = 54/118 (45%), Gaps = 2/118 (1%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
T KG V EC+PENL LK ++ ++ +N I + L+H ++I
Sbjct: 186 TRKKGPWMVIECLPENLSLKIAALAEIERLLPENCIIASNSSSLMTSEMAPHLQHPGRLI 245
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREI--DGFVLNRI 407
+H PP V +VE++ + T + M+ +G P+ + + GF+ NRI
Sbjct: 246 NTHYYIPPRNV-MVEVMSSSHTYEGIFPFLTREMKNMGLTPMVVPPGVQSQGFIFNRI 302
>UniRef50_Q4PFL4 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 344
Score = 49.6 bits (113), Expect = 8e-05
Identities = 36/148 (24%), Positives = 59/148 (39%), Gaps = 2/148 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AVK V E + EN+ +KK +F LD + + +E + + Q +
Sbjct: 125 AVKDTDLVIEAIIENVGIKKDLFGFLDGKAPKDALFASNTSSLSITDVAEAVSAQRQELF 184
Query: 571 S--HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYA 398
H NP + LVE+V T + E+ + +G+ PV+ + GF++NR+
Sbjct: 185 GGFHAFNPVPQMKLVEVVRTTKTSNDTFDSLTEVAKRMGKTPVACI-DSPGFIVNRLLVP 243
Query: 397 ILDEVWRLXXXXXXXXXXXXXVMSEGLG 314
+ E RL M G G
Sbjct: 244 YMLEAIRLVERGEATAKDVDIAMKLGAG 271
>UniRef50_Q3IIH0 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=4;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Pseudoalteromonas haloplanktis (strain TAC 125)
Length = 281
Score = 49.2 bits (112), Expect = 1e-04
Identities = 30/122 (24%), Positives = 56/122 (45%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV + + E + E+ K +F L ++D+ I + L + V+
Sbjct: 78 AVVNSDLIIEAIVEDFTAKMVLFSKLAEFINDSVIVASNTSSLSITAFASVLPNPQNVVG 137
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + LVEI+ T P + + + + +G+ PV + +E GFV+NR+ ++
Sbjct: 138 LHFFNPAPIMELVEIIVGHETAPAKIQLLQGLTKNLGKVPV-VVQEAPGFVVNRMLIPMI 196
Query: 391 DE 386
+E
Sbjct: 197 NE 198
>UniRef50_A3ZZK1 Cluster: 3-hydroxybutyryl-coA dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep:
3-hydroxybutyryl-coA dehydrogenase - Blastopirellula
marina DSM 3645
Length = 319
Score = 49.2 bits (112), Expect = 1e-04
Identities = 26/120 (21%), Positives = 54/120 (45%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNP 554
FV E +PE+ +K++ L+ ++ ++T + ++I H P
Sbjct: 85 FVIESIPEDPVIKQETIAALERLLPNSTPIASNTSALPISLLQAHCQLPQRIIGMHWAEP 144
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
+ +EI+ T A + ++G+ P + R++ GF++NR+ YA+ E + L
Sbjct: 145 CHLTRFLEIIRGEHTDDATADSAANLGRQLGKDPTIVQRDVPGFIVNRLAYAMYREAFWL 204
>UniRef50_A4YDR4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=2; Sulfolobaceae|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Metallosphaera sedula DSM 5348
Length = 334
Score = 49.2 bits (112), Expect = 1e-04
Identities = 27/112 (24%), Positives = 56/112 (50%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V E++ +K V + + D+ I S +++ + + H NPP
Sbjct: 80 VIEAVFEDIKVKSDVLGRVSPLTDE--IIASNTSSLPITELSRAVRNPERFLGMHFFNPP 137
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
+ LVE++ T E ++ +I++ +G+ P+ + +++ GFV+NRI + +
Sbjct: 138 VLMKLVEVIRGDNTSEERFREALDIVKSLGKYPLPVRKDVFGFVVNRILFRL 189
>UniRef50_Q6V1N6 Cluster: PlmT8; n=1; Streptomyces sp. HK803|Rep:
PlmT8 - Streptomyces sp. HK803
Length = 571
Score = 48.8 bits (111), Expect = 1e-04
Identities = 36/146 (24%), Positives = 57/146 (39%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV V E V E++D+K+ VF+ LD+V T+ + V+
Sbjct: 366 AVAACDLVVEAVVEDIDVKRTVFRELDAVCGAQTVLATSTSSLPVIECAMATGRPEAVVG 425
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + LVE+V T E +G++PV + GF++N + + L
Sbjct: 426 MHFFNPAPVMKLVEVVRTALTSRETLGVAHATATALGKRPVGCL-DRSGFIVNALLFPYL 484
Query: 391 DEVWRLXXXXXXXXXXXXXVMSEGLG 314
+ L VM+ G G
Sbjct: 485 NRAVALLDEGILTAEGIDTVMALGQG 510
Score = 36.7 bits (81), Expect = 0.62
Identities = 42/192 (21%), Positives = 69/192 (35%), Gaps = 3/192 (1%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+ A V E VPE + K ++ + + + + G + +
Sbjct: 65 IVSADLVIEAVPERMKTKCELLSHAHNACAPGAVFATTTSGLAVTDIAFGSGRPCRTVGL 124
Query: 568 H--PVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H P P VE+V P T V + ++ ++GQ PVS+ + GFV + A
Sbjct: 125 HLFPQGPMDPATAVEVVGTPLTDGSVLADVQALIRDLGQVPVSVP-DRAGFVGGALTMAY 183
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAEGMQSYIDRYGETIYRV 215
L++ + M G G+ L AHL+A G+ D R
Sbjct: 184 LNDAATMYEQRYASRDGIDTAMRLGCGLPRGPL-----AHLDAIGLDVARDTLDALHERT 238
Query: 214 SN-EMGPAPRMT 182
+ PAP +T
Sbjct: 239 GDRRFLPAPVLT 250
>UniRef50_A5IDB6 Cluster: 3-hydroxyacyl CoA dehydrogenase; n=9;
Gammaproteobacteria|Rep: 3-hydroxyacyl CoA dehydrogenase
- Legionella pneumophila (strain Corby)
Length = 284
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/121 (23%), Positives = 58/121 (47%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+K + ++ E + EN + KK ++Q L I + + H +VI
Sbjct: 81 LKQSEYIIENITENWERKKALYQVLKKECSATCILGVNTSSIPITKIASLVDHPQRVIGV 140
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H +NP +P+VE++ T +KTR ++E++ ++ + + ++ GFV NR ++
Sbjct: 141 HFMNPAPMMPMVEVIKGYHTDELTIEKTRTLLEQVHKKMI-VVKDSVGFVSNRAMMIFIN 199
Query: 388 E 386
E
Sbjct: 200 E 200
>UniRef50_Q1D1F2 Cluster: Fatty oxidation complex, alpha subunit
FadJ; n=2; Cystobacterineae|Rep: Fatty oxidation
complex, alpha subunit FadJ - Myxococcus xanthus (strain
DK 1622)
Length = 746
Score = 48.4 bits (110), Expect = 2e-04
Identities = 33/120 (27%), Positives = 56/120 (46%)
Frame = -2
Query: 745 KGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSH 566
K A V E V E+L LK ++ +++V D TI ++G + +QVI H
Sbjct: 428 KSADLVIEAVFEDLKLKHRIIAEVEAVTGDQTIFASNTSSIPITELAKGSRRPAQVIGMH 487
Query: 565 PVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+P + +PL+EI+ T V E+ + G + V + + GF +RI ++E
Sbjct: 488 YFSPVHKMPLLEIITHAGTADWVTATCVEVGRKQG-KTVIVVNDGPGFYTSRILAPYMNE 546
>UniRef50_A5V327 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=2; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Sphingomonas wittichii RW1
Length = 748
Score = 48.4 bits (110), Expect = 2e-04
Identities = 31/115 (26%), Positives = 52/115 (45%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A V E V E++ +KK++F +L+ V T+ + L +
Sbjct: 420 AVADADLVIEAVFEDMAVKKEIFSDLEKRVKPGTVLASNTSALDVDEIAAALDRPEDFVG 479
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H +P + L+E+V A + PE + +IG+ PV + DGF+ NR+
Sbjct: 480 MHFFSPANVMKLLEVVQAAKSSPEAILTAMAVGRKIGKVPV-WSGNCDGFIGNRM 533
>UniRef50_A1CC71 Cluster: 3-hydroxyacyl-CoA dehydrogenase, putative;
n=2; Aspergillus|Rep: 3-hydroxyacyl-CoA dehydrogenase,
putative - Aspergillus clavatus
Length = 307
Score = 48.4 bits (110), Expect = 2e-04
Identities = 37/123 (30%), Positives = 52/123 (42%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
TAV+ A V E +PE L LK ++F LD + + I E + +++V
Sbjct: 88 TAVQNAWMVIEAIPELLPLKIELFGQLDQLAPADCILATNSSSYKSREMLEKVARRARVC 147
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
+H PP L EI+ +T P + E G PV E G + NRI AI
Sbjct: 148 NAHYYMPPEQNHL-EIMTCGFTDPAIISFLLEQAAAAGFVPVHAKVESTGLIFNRIWAAI 206
Query: 394 LDE 386
E
Sbjct: 207 KRE 209
>UniRef50_Q9RUA4 Cluster: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase; n=18;
Bacteria|Rep: Enoyl-CoA hydratase/3,2-trans-enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase - Deinococcus
radiodurans
Length = 708
Score = 48.0 bits (109), Expect = 3e-04
Identities = 35/123 (28%), Positives = 53/123 (43%)
Frame = -2
Query: 742 GAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHP 563
GA + E V EN+D+KK +F LD + I + QVI H
Sbjct: 386 GADIIIEAVFENMDVKKDIFTRLDKIAKPGAILASNTSTLDVNEIASVTGRPEQVIGLHF 445
Query: 562 VNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEV 383
+P + L+EIV A T V + + + I + V + DGFV NR+ + DE
Sbjct: 446 FSPANVMKLLEIVRADKTSDSVLATSLALAKRIKKVGV-VVGVCDGFVGNRMVHRYGDEA 504
Query: 382 WRL 374
++
Sbjct: 505 RKI 507
>UniRef50_Q2S396 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family; n=1; Salinibacter ruber DSM
13855|Rep: 3-hydroxyacyl-CoA dehydrogenase, C-terminal
domain family - Salinibacter ruber (strain DSM 13855)
Length = 802
Score = 47.6 bits (108), Expect = 3e-04
Identities = 28/115 (24%), Positives = 56/115 (48%), Gaps = 3/115 (2%)
Frame = -2
Query: 742 GAI-FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLK--HKSQVIV 572
GA+ ++ E V E +D+K+ V +++ D+ + +EG K + +
Sbjct: 101 GAVDWIVEAVVERMDVKRDVHARIEAHAADDAVISTNTSGLPIHAITEGRSADFKRRFLG 160
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+H NPP Y+ L+E+VP T P+V ++ + + + + ++ F+ NRI
Sbjct: 161 THFYNPPRYLKLLELVPTDATDPDVTERVAQFGRLRLGKGIVVANDVPYFIGNRI 215
>UniRef50_Q1YTH7 Cluster: Fatty oxidation complex, alpha subunit;
n=4; Gammaproteobacteria|Rep: Fatty oxidation complex,
alpha subunit - gamma proteobacterium HTCC2207
Length = 718
Score = 47.6 bits (108), Expect = 3e-04
Identities = 27/111 (24%), Positives = 52/111 (46%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E V E +KK V +++++D++ + +E L+ H NP +
Sbjct: 402 EAVVELESVKKMVLPAVEALLDNSAVITSNTSTISINRLAESLERPQNFCGMHFFNPVHA 461
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+PLVEI+ T E +G++P+ + + GF++NR+ +A+L
Sbjct: 462 MPLVEIIRGENTSDETIAAVCAYALGLGKKPI-VVNDCPGFLVNRVLFAML 511
>UniRef50_A0LDJ8 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Magnetococcus sp. MC-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Magnetococcus sp. (strain MC-1)
Length = 717
Score = 47.6 bits (108), Expect = 3e-04
Identities = 32/143 (22%), Positives = 62/143 (43%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V E + E++ K++++ L+ + ++ + ++GLK Q++ H
Sbjct: 385 ADLVIEAIFEDVTAKQQLYAALEPRMREHALLATNTSAIPLQTLAQGLKRPQQLLGLHFF 444
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
NP +PLVE+V P T + + + I + P+ + + GF++NR+ L E
Sbjct: 445 NPVARMPLVEVVEGPQTSMQALQMGYRFVHAIQRLPLPV-KSRPGFLVNRVLMPYLMEAV 503
Query: 379 RLXXXXXXXXXXXXXVMSEGLGM 311
R+ M G+ M
Sbjct: 504 RMVDEGVDMRRIDKAAMDFGMPM 526
>UniRef50_Q4Q939 Cluster: Trifunctional enzyme alpha subunit,
mitochondrial-like protein; n=6; Trypanosomatidae|Rep:
Trifunctional enzyme alpha subunit, mitochondrial-like
protein - Leishmania major
Length = 726
Score = 47.6 bits (108), Expect = 3e-04
Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 2/126 (1%)
Frame = -2
Query: 745 KGAIFVQECVPENLDLKKKVFQNL--DSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
+ A + E E +D+KKKV Q L D ++ ++ K ++
Sbjct: 385 RDADVIVEAAVEVMDIKKKVIQQLEKDGILHSKSLFATNTSSLSLTEMQTVAKCPHNIVG 444
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP +PLVE++ T E A + + G+ P+ + + GF++NRI +
Sbjct: 445 MHFFNPVSKMPLVEVIKGKSTSTEAAAAIFNLALKTGKIPI-IVNDGPGFLVNRILGVYM 503
Query: 391 DEVWRL 374
E RL
Sbjct: 504 AEAGRL 509
>UniRef50_Q1YHC5 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Aurantimonas sp. SI85-9A1|Rep:
Putative 3-hydroxybutyryl-CoA dehydrogenase -
Aurantimonas sp. SI85-9A1
Length = 286
Score = 47.2 bits (107), Expect = 4e-04
Identities = 36/155 (23%), Positives = 60/155 (38%), Gaps = 2/155 (1%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVV--DDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVN 557
V E +PE+L LK F+++++ D + ++ L + H +
Sbjct: 58 VVEAIPEDLALKTAFFRSVEARYGPDSVPLMASNTSGLPLQDIADRLARPDLFLGIHWFH 117
Query: 556 PPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 377
P +P+VE V T P ++ G + + R + G V+NR+Q+AIL E +
Sbjct: 118 PADELPMVESVRVAETAPATVDTALALLRAAGWDSIVVPRPVPGAVVNRLQHAILHEAYH 177
Query: 376 LXXXXXXXXXXXXXVMSEGLGMRYAFLGALETAHL 272
L LG R G L+ L
Sbjct: 178 LMAEGLASVEDIDRAARWLLGPRMCIAGLLKQKDL 212
>UniRef50_A1BCA2 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Paracoccus denitrificans PD1222|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Paracoccus denitrificans (strain Pd 1222)
Length = 371
Score = 47.2 bits (107), Expect = 4e-04
Identities = 27/105 (25%), Positives = 48/105 (45%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E V E + +K+ +F L++VV + + +EGL +++ H NP
Sbjct: 86 EAVVERMPVKQSLFAALEAVVAPDAVLASNTSSLSMAAMAEGLARPERLLGLHFFNPAPV 145
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 410
+ LVE+V P T + R + E G+ + + GF++NR
Sbjct: 146 MKLVELVAHPGTGAAALDRARRLTEAAGKTVIPCP-DRPGFIVNR 189
>UniRef50_P34439 Cluster: Probable 3-hydroxyacyl-CoA dehydrogenase
F54C8.1; n=2; Caenorhabditis|Rep: Probable
3-hydroxyacyl-CoA dehydrogenase F54C8.1 - Caenorhabditis
elegans
Length = 298
Score = 47.2 bits (107), Expect = 4e-04
Identities = 33/147 (22%), Positives = 61/147 (41%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
TAV A + E EN+DLK+ +F ++ ++I ++GL+ K++
Sbjct: 91 TAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILTTNTSSFLLEDVAKGLQDKTRFG 150
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H NP + L+E++ + T E + +G+ V+ ++ GF++NR+
Sbjct: 151 GLHFFNPVPVMKLLEVIRSDDTSDETYATLIKFGTAVGKTTVA-CKDSPGFIVNRLLIPY 209
Query: 394 LDEVWRLXXXXXXXXXXXXXVMSEGLG 314
E R+ M G G
Sbjct: 210 FFEAARMYERGDASMTDIDEAMKLGAG 236
>UniRef50_Q5LVD0 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=6; Rhodobacterales|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 698
Score = 46.8 bits (106), Expect = 6e-04
Identities = 32/115 (27%), Positives = 53/115 (46%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ A V E V E++++KK+VF LD+V + + V+
Sbjct: 366 ALADADLVIEAVFEDMEVKKQVFTKLDAVCKPGAVLASNTSYLDINQIAAVTSRPQDVLG 425
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H +P + + L+E+V A T P+VA + + +G+ V DGF+ NRI
Sbjct: 426 LHFFSPAHVMKLLEVVIADQTAPDVAATGFALGKRLGKVSVR-AGVCDGFIGNRI 479
>UniRef50_A3ZYI9 Cluster: Fatty oxidation complex, alpha subunit
FadB; n=1; Blastopirellula marina DSM 3645|Rep: Fatty
oxidation complex, alpha subunit FadB - Blastopirellula
marina DSM 3645
Length = 724
Score = 46.8 bits (106), Expect = 6e-04
Identities = 27/125 (21%), Positives = 55/125 (44%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
V + V E + ENL++K+K++ L+ + D+ I + L + +
Sbjct: 394 VAASKLVIEAIVENLEVKRKIYARLEPQLADDAILASNTSTLPITQLAANLAKPERFVGI 453
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H NP + LVE++ T + +G+ P+ + + GF++NR+ + ++
Sbjct: 454 HFFNPVRKMKLVEVIRGAQTSDATVASAVAFAKRLGKFPI-VVNDGPGFLVNRLLFPYMN 512
Query: 388 EVWRL 374
E L
Sbjct: 513 EALAL 517
>UniRef50_A3JQP6 Cluster: Acetoacetyl-CoA reductase; n=2;
Alphaproteobacteria|Rep: Acetoacetyl-CoA reductase -
Rhodobacterales bacterium HTCC2150
Length = 780
Score = 46.8 bits (106), Expect = 6e-04
Identities = 27/111 (24%), Positives = 51/111 (45%), Gaps = 2/111 (1%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVIVSHPV 560
++ E + E LD+KK ++Q L+ V+ + E + +++ ++H
Sbjct: 88 WIVEAIVERLDIKKALYQRLNDVISPECVVTSNTSTIPIKLLVEDMPQDFRARFAITHYF 147
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
NP Y+ L+E+V T P V + +EI + V + GF+ NR+
Sbjct: 148 NPVRYMRLLELVRGADTNPAVMDRLARYNDEILGKGVVQCGDTPGFLGNRV 198
>UniRef50_A7PEM6 Cluster: Chromosome chr11 scaffold_13, whole genome
shotgun sequence; n=3; core eudicotyledons|Rep:
Chromosome chr11 scaffold_13, whole genome shotgun
sequence - Vitis vinifera (Grape)
Length = 724
Score = 46.8 bits (106), Expect = 6e-04
Identities = 27/107 (25%), Positives = 49/107 (45%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V EN+ LK+K+F ++ + + I E + ++I +H +P
Sbjct: 391 VIEAVIENISLKQKIFSEIEKICSPHCILATNTSTIDLNLVGEKTSSQDRIIGAHFFSPA 450
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 410
+ +PL+E+V T +V + + I + PV + GF +NR
Sbjct: 451 HVMPLLEVVRTEKTSAQVILDLMTVGKAIKKIPV-VVGSCTGFAVNR 496
>UniRef50_Q876X5 Cluster: Dehydrogenase; n=7; Pezizomycotina|Rep:
Dehydrogenase - Fusarium sporotrichioides
Length = 285
Score = 46.8 bits (106), Expect = 6e-04
Identities = 38/125 (30%), Positives = 55/125 (44%), Gaps = 2/125 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQV 578
AV A V E VPE L +K F +L+ + ++TI L+ K +V
Sbjct: 79 AVAKAWLVIETVPEKLPIKIATFTDLERLTSEDTILCSNSSSYKSREMVGDLRPDTKRRV 138
Query: 577 IVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYA 398
+ H PP Y +VE++ T + E +EEI P +E GF+ NR+ A
Sbjct: 139 LNMHYYLPPDY-RVVELMTDGETDESIFPFLSEKLEEIRFHPYVARKESTGFIYNRLWAA 197
Query: 397 ILDEV 383
I EV
Sbjct: 198 IKREV 202
>UniRef50_Q8ZAN0 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=116; cellular
organisms|Rep: Fatty acid oxidation complex subunit
alpha [Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Yersinia pestis
Length = 729
Score = 46.4 bits (105), Expect = 8e-04
Identities = 26/119 (21%), Positives = 53/119 (44%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
++ A + E V EN +K V +++++ ++T+ ++ LK
Sbjct: 390 IERAQVIVEAVVENPKVKAAVLAEVEALIGEDTVLASNTSTIPIDQLAKSLKRPENFCGM 449
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + +PLVEI+ T + ++G+ P+ + + GF +NR+ + L
Sbjct: 450 HFFNPVHRMPLVEIIRGAKTSDKTLAAVVAYATQMGKTPI-VVNDCPGFFVNRVLFPYL 507
>UniRef50_A0QZQ9 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Mycobacterium smegmatis str. MC2 155|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Mycobacterium
smegmatis (strain ATCC 700084 / mc(2)155)
Length = 293
Score = 46.0 bits (104), Expect = 0.001
Identities = 36/156 (23%), Positives = 64/156 (41%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V EN ++KK + + +VV NT + L + S+V H NP
Sbjct: 91 VVESVTENAEVKKDLLGRVAAVVGVNTPICTNTSALSVTELAAALPNPSRVAGLHFFNPA 150
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLX 371
VE+V A T E+ + +++ +G + + ++ GF+LN + L++V
Sbjct: 151 PLQRTVEVVRALQTGEELVDRLVALVDTLGNKDPIVVKDRPGFLLNALLLPYLNDVISEY 210
Query: 370 XXXXXXXXXXXXVMSEGLGMRYAFLGALETAHLNAE 263
+ GLG + L L+ L+ +
Sbjct: 211 DDGLATAEDIDLALKLGLGYKSGPLELLDMIGLDVQ 246
>UniRef50_Q5P039 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=3;
Proteobacteria|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Azoarcus sp. (strain EbN1) (Aromatoleum aromaticum
(strain EbN1))
Length = 443
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/114 (26%), Positives = 53/114 (46%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+K A V E V E++ LK+ +F+ LD++V + I + + V+ +
Sbjct: 118 LKDADLVIEAVFEDMALKQDIFRKLDAIVHPDAILATNTSGLDIDEIAVVTRRPQDVVGA 177
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H +P + L+E+V T PEV + +G+ V L+R GF+ N +
Sbjct: 178 HFFSPAHVQKLLEVVRGARTAPEVIATLMSLGRRMGKVSV-LSRIYPGFIGNAL 230
>UniRef50_Q0SEV8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=34;
Bacteria|Rep: 3-hydroxybutyryl-CoA dehydrogenase -
Rhodococcus sp. (strain RHA1)
Length = 298
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/109 (27%), Positives = 48/109 (44%), Gaps = 1/109 (0%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDD-NTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNP 554
V E V E+ +K ++F LD VV D N + K +VI H NP
Sbjct: 89 VVEAVVEDEKVKSEIFTELDQVVTDPNAVLASNTSSIPIMKLGIATKSPERVIGMHFFNP 148
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+PLVE+V T V+++ ++ + V + + GFV+N +
Sbjct: 149 VPVLPLVELVTTLKTSKSVSERAEAFASDVLGKQVVRSADRSGFVVNAL 197
>UniRef50_A1IFR8 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 304
Score = 45.6 bits (103), Expect = 0.001
Identities = 28/121 (23%), Positives = 49/121 (40%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A A F+ E V E++++K +VF+ + I + + +
Sbjct: 86 AAANADFISESVTESVEIKCRVFETFHPLCPARAIFTTNTSSLIPSMLTHAVGRPDRFAA 145
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H N +V+I+P P T PE A+ R +GQ P+ +E G+ N + +
Sbjct: 146 FHFHNT-LTSDIVDIMPHPGTTPETAETIRAFALRLGQVPIVFKKENHGYAFNALLMNLC 204
Query: 391 D 389
D
Sbjct: 205 D 205
>UniRef50_A1FD08 Cluster: 3-hydroxybutyryl-CoA epimerase; n=13;
cellular organisms|Rep: 3-hydroxybutyryl-CoA epimerase -
Pseudomonas putida W619
Length = 423
Score = 45.6 bits (103), Expect = 0.001
Identities = 33/127 (25%), Positives = 56/127 (44%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
T + A V E V ENL LK+++F+ LDS + I + QV+
Sbjct: 93 TELAEADLVIEAVYENLALKQEIFRALDSTLKPEAILASNTSALDIDAIAAVTGRPEQVL 152
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H +P + + L+E+V T P V + + +G++ V + GF+ NR+
Sbjct: 153 GLHFFSPAHVMKLLEVVRGQLTAPAVLDAAVALGQRMGKE-VVVAGNCPGFIGNRMLRTY 211
Query: 394 LDEVWRL 374
+ E +L
Sbjct: 212 VAEARQL 218
>UniRef50_A0K022 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=9; Actinomycetales|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Arthrobacter sp. (strain FB24)
Length = 290
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/119 (24%), Positives = 52/119 (43%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E VPE+ +LK + +++ + D+ + LK + H NP
Sbjct: 93 VVEAVPEDWELKVASLREIEARLSDDAYLASNTSSLSVNGLARELKRPGNFLGLHFFNPV 152
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
L+E+V T P++A + +E +G+ V + + GF +R+ AI E R+
Sbjct: 153 PASTLIEVVLGEQTSPDLAAAAKRWVEALGKTAV-VVNDAPGFASSRLGVAIALEAMRM 210
>UniRef50_Q0C7S2 Cluster: Putative uncharacterized protein; n=1;
Aspergillus terreus NIH2624|Rep: Putative
uncharacterized protein - Aspergillus terreus (strain
NIH 2624)
Length = 589
Score = 45.6 bits (103), Expect = 0.001
Identities = 32/123 (26%), Positives = 52/123 (42%), Gaps = 2/123 (1%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVI 575
V A V E VPE + LK F+ LD + + I + + K +++
Sbjct: 84 VNNAWLVIEAVPEKIQLKIDTFEQLDKLAPTDCILASNSSSYKSSEMLDKVSDSAKPRIL 143
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
H PP V +VE++ +T P + + E +E P +E GF+ NR+ A+
Sbjct: 144 NMHYYMPPQ-VMVVELMTNGFTDPSIIQFLVERSKEAATIPYVARKESTGFIFNRLWAAV 202
Query: 394 LDE 386
E
Sbjct: 203 KRE 205
>UniRef50_Q5LVG3 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=2; Rhodobacteraceae|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Silicibacter pomeroyi
Length = 681
Score = 45.2 bits (102), Expect = 0.002
Identities = 36/138 (26%), Positives = 62/138 (44%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E V E+LD+K+ VF +L +V+ + I G+ + ++ + H +P +
Sbjct: 371 EAVFEDLDVKRIVFADLAAVMRPDAILATNTSYLDPQLVFAGIANPARCLGLHFFSPAHV 430
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRLXXX 365
+ L+EIV P T PEV + + + + V L+ DGF+ NR+ A E L
Sbjct: 431 MKLLEIVKTPDTAPEVLATGFALGKRLRKISV-LSGICDGFIGNRMLAAYRREAEYLLAD 489
Query: 364 XXXXXXXXXXVMSEGLGM 311
+ ++GL M
Sbjct: 490 GALPHEVDAAMRAQGLPM 507
>UniRef50_A7INS1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=5; Alphaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Xanthobacter sp. (strain Py2)
Length = 789
Score = 45.2 bits (102), Expect = 0.002
Identities = 29/112 (25%), Positives = 54/112 (48%), Gaps = 3/112 (2%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVIVSHPV 560
++ E V E LD+K+ ++ +++ + + GL + +++H
Sbjct: 102 WIVEAVIERLDIKQALYAKIEAARRPGSAVSSNTSTIPLGDLTAGLPESFRRDFLITHFF 161
Query: 559 NPPYYVPLVEIVPAPWTKP-EVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
NPP Y+ L+EIV P T P VA R ++G+ V+ ++ GF+ NR+
Sbjct: 162 NPPRYMRLLEIVAGPETNPATVAAVARFADVKLGKTVVT-CKDTPGFIANRL 212
>UniRef50_A5IPA0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=14; Staphylococcus|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Staphylococcus aureus subsp. aureus JH9
Length = 753
Score = 45.2 bits (102), Expect = 0.002
Identities = 24/116 (20%), Positives = 51/116 (43%), Gaps = 2/116 (1%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQ--VIVSHPVNPP 551
E V E++++K V+Q + ++ + ++ K Q H NPP
Sbjct: 88 EAVKEDIEIKHAVWQQVLQHAKEDALFATNTSGIPINAIAQAFNEKDQERFFGLHFFNPP 147
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEV 383
+ LVE++P TK + + + + + V + ++ GFV NR+ ++++
Sbjct: 148 RIMKLVELIPTSHTKESIILDVKNFAQNVLGKGVIVVNDVPGFVANRVGTQTMNDI 203
>UniRef50_Q89SH2 Cluster: Blr2428 protein; n=7; Rhizobiales|Rep:
Blr2428 protein - Bradyrhizobium japonicum
Length = 715
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/113 (25%), Positives = 51/113 (45%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
V+ A V E VPE L+LK+KV+ L+ + I L +++
Sbjct: 413 VRNADLVIEAVPEKLELKQKVYAGLEPKMKPGAILATNTSSIPLQDLRTTLARPDRLVGL 472
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 410
H NP + LVE+V +V ++ + I + P+++ + GF++NR
Sbjct: 473 HFFNPVSRLQLVEVVSHDGNDAQVLREALAFVGAIDRLPLAV-KSSPGFLVNR 524
>UniRef50_Q1INT0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Acidobacteria bacterium
Ellin345|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Acidobacteria bacterium (strain
Ellin345)
Length = 806
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/121 (23%), Positives = 61/121 (50%), Gaps = 4/121 (3%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVIVSHPV 560
++ E V ENL+LK+ + + +++V ++ SEG + +H
Sbjct: 91 WIIEAVVENLELKRALLKKVEAVRKPGSLITTNTSGLPVSKISEGFSEDFRRNWFGTHFF 150
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIME-EIGQQPVSLTREIDGFVLNRI-QYAILDE 386
NPP Y+ L+E++P P T P+ + + + ++G+ V ++ F+ NRI +++L+
Sbjct: 151 NPPRYMRLLELIPTPDTDPKAMEAVAHLGDVQLGKGIVH-AKDTPNFIGNRIGTFSVLNV 209
Query: 385 V 383
+
Sbjct: 210 I 210
>UniRef50_O28262 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Archaeoglobus fulgidus|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Archaeoglobus fulgidus
Length = 281
Score = 44.8 bits (101), Expect = 0.002
Identities = 33/125 (26%), Positives = 58/125 (46%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
VK V E V E+L+ K +V + ++ + N +E L S+ +
Sbjct: 59 VKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSVISVDDIAERLDSPSRFLGV 116
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H +NPP+ +PLVEIV + +T + + E+G++ V + ++NR A+L
Sbjct: 117 HWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVVVCKGQ---SLVNRFNAAVLS 173
Query: 388 EVWRL 374
E R+
Sbjct: 174 EASRM 178
>UniRef50_Q8W1L6 Cluster: Peroxisomal fatty acid beta-oxidation
multifunctional protein (MFP) [Includes: Enoyl-CoA
hydratase/3-2-trans-enoyl-CoA isomerase/3-
hydroxybutyryl-CoA epimerase (EC 4.2.1.17) (EC 5.3.3.8)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)]; n=23; Magnoliophyta|Rep: Peroxisomal fatty
acid beta-oxidation multifunctional protein (MFP)
[Includes: Enoyl-CoA hydratase/3-2-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Oryza sativa subsp.
japonica (Rice)
Length = 726
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/112 (25%), Positives = 49/112 (43%)
Frame = -2
Query: 745 KGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSH 566
K V E V E + LK+ +F +L+ V + I E + ++I +H
Sbjct: 387 KDVDMVIEAVIEKIPLKQSIFSDLEKVCPPHCILATNTSTIDLNVVGEKTNSQDRIIGAH 446
Query: 565 PVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 410
+P + +PL+EIV T P+ + + I + PV + GF +NR
Sbjct: 447 FFSPAHIMPLLEIVRTEKTSPQAILDLITVGKMIKKVPV-VVGNCTGFAVNR 497
>UniRef50_Q6D2L7 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=16;
Gammaproteobacteria|Rep: Fatty acid oxidation complex
subunit alpha [Includes: Enoyl-CoA
hydratase/3-hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase (EC
1.1.1.35)] - Erwinia carotovora subsp. atroseptica
(Pectobacterium atrosepticum)
Length = 731
Score = 44.8 bits (101), Expect = 0.002
Identities = 30/118 (25%), Positives = 53/118 (44%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V E V E+L LK+++ ++ +TI +EG + V+ H
Sbjct: 403 ADIVIEAVFEDLALKRQMITEIEDHAAPHTIFASNTSSLPIHQIAEGARRPQLVVGLHYF 462
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+P +PLVE++P T E T + + G+ + + + GF +NRI ++E
Sbjct: 463 SPVDKMPLVEVIPHAHTSAETVATTVALARKQGKTAI-VVGDSAGFYVNRILAPYINE 519
>UniRef50_Q2W2Y1 Cluster: Glyoxysomal fatty acid beta-oxidation
multifunctional protein MFP-a; n=3;
Magnetospirillum|Rep: Glyoxysomal fatty acid
beta-oxidation multifunctional protein MFP-a -
Magnetospirillum magneticum (strain AMB-1 / ATCC 700264)
Length = 703
Score = 44.4 bits (100), Expect = 0.003
Identities = 32/115 (27%), Positives = 53/115 (46%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+K A E V E ++LKK +F LD+V+ I + K + VI
Sbjct: 370 ALKDADLAIEAVFEKMELKKDIFAKLDAVLPAGAILGTNTSTLDIDEIANTTKRPADVIG 429
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H +P +PL+EIV T +V ++ + I + V +++ GF+ NR+
Sbjct: 430 LHFFSPANVMPLLEIVQGKQTAMDVLLTALDMAKLIKKTGV-VSKVCYGFIGNRM 483
>UniRef50_Q1ISD6 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Acidobacteria bacterium Ellin345|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Acidobacteria bacterium (strain Ellin345)
Length = 293
Score = 44.4 bits (100), Expect = 0.003
Identities = 27/106 (25%), Positives = 47/106 (44%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E + EN+ K K++ L+ V + I K + I H NP
Sbjct: 87 EAILENVPEKHKMYAALEKVAKPDAIFASNTSSISITELMAATKRPERFIGLHFFNPVPL 146
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+ LVE++ T EV + + ++G+ PV T++ GF++NR+
Sbjct: 147 MKLVEVIRTIATSDEVFEAAVDFGTKLGKVPVR-TKDSSGFIVNRL 191
>UniRef50_A0ISW5 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Serratia proteamaculans 568|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding - Serratia
proteamaculans 568
Length = 509
Score = 44.4 bits (100), Expect = 0.003
Identities = 28/126 (22%), Positives = 60/126 (47%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ + V E + E+ K ++ + + V I + G+++ ++ I
Sbjct: 84 AIADSDLVIETIAEHEATKHEILAAIAATVKKEAIIATNTSSLSLNKLAAGVENNARFIG 143
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H NP + L+EI+P+ +T + + ++++ IG+Q V + + GF++NR+
Sbjct: 144 LHFFNPAPLMKLIEIIPSYFTSRATSLRCQQLVTAIGKQFV-VCKATPGFIVNRMARPFY 202
Query: 391 DEVWRL 374
E +RL
Sbjct: 203 LEGFRL 208
>UniRef50_Q3KCL0 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Pseudomonas fluorescens PfO-1|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Pseudomonas fluorescens (strain PfO-1)
Length = 703
Score = 44.0 bits (99), Expect = 0.004
Identities = 34/122 (27%), Positives = 51/122 (41%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A + E V E ++ K +VF L+SV I ++ + VI H
Sbjct: 378 ADLIIEAVCEKMESKHQVFLALESVCKPGAILATNTSSLDIDALAKMVSRPQDVIGMHFF 437
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
+P + LVEIV T P+V +I IG+ PV ++ G + NR+ E
Sbjct: 438 SPANVMRLVEIVLCQTTAPDVVTAVMDIARRIGKLPV-ISGNSAGSIGNRMLEPYAREAH 496
Query: 379 RL 374
RL
Sbjct: 497 RL 498
>UniRef50_Q092W5 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein; n=2;
Cystobacterineae|Rep: 3-hydroxyacyl-CoA
dehydrogenase/enoyl-CoA hydratase/isomerase family
protein - Stigmatella aurantiaca DW4/3-1
Length = 797
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/111 (23%), Positives = 52/111 (46%), Gaps = 2/111 (1%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGL--KHKSQVIVSHPV 560
+V E V E+L +K+ +F+ ++ + + I +G + + + +V+H
Sbjct: 98 WVIEVVKEDLAVKQALFEKVEKHLRKDAIVSSNTSGLSIAGMLQGRGPEFRKRFLVTHFF 157
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
NP Y+ L+E+V P T P V + E + + + ++ F+ NRI
Sbjct: 158 NPVRYMKLLELVAGPETDPAVVRTLHAFGEGVLGKGIVYGKDTTNFIANRI 208
>UniRef50_A7HED1 Cluster: 3-hydroxyacyl-CoA dehydrogenase
NAD-binding; n=4; Deltaproteobacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase NAD-binding -
Anaeromyxobacter sp. Fw109-5
Length = 795
Score = 44.0 bits (99), Expect = 0.004
Identities = 30/112 (26%), Positives = 58/112 (51%), Gaps = 3/112 (2%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVIVSHPV 560
+V E V E+L +K+++ + + + + + +E L + +++V+H
Sbjct: 102 WVIEVVVEDLAVKQQLLGRVAAHLRPDAVLSTNTSGLSVNALAESLPEPLRPRLLVTHFF 161
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIME-EIGQQPVSLTREIDGFVLNRI 407
NPP Y+ LVE+V + +T VA + E++ +G+ VS ++ FV NRI
Sbjct: 162 NPPRYMRLVELVSSRFTDRAVAARMAELLRVRLGKGVVS-AKDTPNFVANRI 212
>UniRef50_A5V4A1 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Sphingomonas wittichii RW1|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor -
Sphingomonas wittichii RW1
Length = 489
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/106 (24%), Positives = 46/106 (43%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E + E +D+K +F+ L V I + + + H NP
Sbjct: 91 EAIVERMDVKTGLFETLARHVAPGAILASNTSSLSIEAMASAVPGPERFAGLHFFNPVPA 150
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+ LVE++P+ T P V +M + PV + R++ GF++NR+
Sbjct: 151 MKLVELIPSSRTAPTVVDDLEALMRAWKKLPVRV-RDVPGFIVNRV 195
>UniRef50_Q5V581 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Haloarcula marismortui|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Haloarcula marismortui (Halobacterium
marismortui)
Length = 290
Score = 44.0 bits (99), Expect = 0.004
Identities = 29/127 (22%), Positives = 57/127 (44%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
+AV G+ V + + ++V +++V+D TI + GL+ + +
Sbjct: 63 SAVSGSDVVIDATNGGTESHREVVAETETMVEDETIIAVSDTSLSVTAVATGLRSPDRAV 122
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAI 395
+ V+PP +VE+V A T + + +E + PV + R+ GF R++ A
Sbjct: 123 GLNLVDPPDGA-IVEVVIAEQTTAATRDRVTDFVESLDASPV-VVRDTPGFAALRLELAA 180
Query: 394 LDEVWRL 374
+ E R+
Sbjct: 181 IAEAIRM 187
>UniRef50_Q45223 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=92;
cellular organisms|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Bradyrhizobium japonicum
Length = 293
Score = 44.0 bits (99), Expect = 0.004
Identities = 26/115 (22%), Positives = 54/115 (46%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E E ++K+K+F L +V+ I + + I H +NP
Sbjct: 88 VIETAVEKEEVKRKIFHELCAVLKPEAIVASDTSSISITRLAAATDRPERFIGIHFMNPV 147
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+ LVE++ T + ++E + ++G+Q V+++ + F++NRI +++E
Sbjct: 148 PLMELVELIRGIATDDATFEASKEFVAKLGKQ-VAVSEDFPAFIVNRILLPMINE 201
>UniRef50_Q8EYS5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=4;
Leptospira|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Leptospira interrogans
Length = 436
Score = 43.6 bits (98), Expect = 0.005
Identities = 32/125 (25%), Positives = 57/125 (45%), Gaps = 2/125 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQ--V 578
AV + +V E V E+ ++K+ + + + S TI S+ Q
Sbjct: 74 AVSESDWVFELVAESYEVKEPINKRIASSRRPGTIVSTVSSGLSIERLSKAFDEDGQKHY 133
Query: 577 IVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYA 398
+H NPPY + L E+V + +V K+ E +E++ + V T + F NRI +
Sbjct: 134 FGTHFFNPPYKMILCELVSHKGSDKKVLKQLGEYLEKVLGRAVVYTNDTPAFAGNRIGFQ 193
Query: 397 ILDEV 383
+++EV
Sbjct: 194 LINEV 198
>UniRef50_Q5P5K6 Cluster: Fusion of 3-hydroxyacyl-CoA dehydrogenase
and enoyl-CoA hydratase; n=20; Proteobacteria|Rep:
Fusion of 3-hydroxyacyl-CoA dehydrogenase and enoyl-CoA
hydratase - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 797
Score = 43.6 bits (98), Expect = 0.005
Identities = 29/111 (26%), Positives = 50/111 (45%), Gaps = 3/111 (2%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVIVSHPVN 557
V E + E L+ K+ ++ + + I +EGL +S+ H N
Sbjct: 90 VIEAIAEKLEWKRDLYAKAAPYLRPDAIFASNTSGLSIATLAEGLPEALRSRFCGVHFFN 149
Query: 556 PPYYVPLVEIVPAPWTKPEVAKKTRE-IMEEIGQQPVSLTREIDGFVLNRI 407
PP Y+ LVE++PAP T P + ++ +G+ V ++ FV NR+
Sbjct: 150 PPRYMALVELIPAPATDPLMLDALEAWLVTRLGKSIVR-AKDTPNFVANRV 199
>UniRef50_A4BL13 Cluster: Fatty oxidation complex, alpha subunit;
n=3; Proteobacteria|Rep: Fatty oxidation complex, alpha
subunit - Nitrococcus mobilis Nb-231
Length = 726
Score = 43.6 bits (98), Expect = 0.005
Identities = 30/119 (25%), Positives = 54/119 (45%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V E+L+LK ++ + +++ + + I ++ + VI H +P
Sbjct: 413 VIEAVFEDLELKHRMIREVEANCNADVIFASNTSSLPLARIAQAAERPQNVIGLHYFSPV 472
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
+PL+E++ T PEV G+ P+ + R+ GF +NRI L+E L
Sbjct: 473 DRMPLLEVIAHERTAPEVIATAMAFGRAQGKTPI-VVRDGVGFYVNRILAPYLNEAVHL 530
>UniRef50_A1I839 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxybutyryl-CoA dehydrogenase - Candidatus
Desulfococcus oleovorans Hxd3
Length = 289
Score = 43.6 bits (98), Expect = 0.005
Identities = 28/111 (25%), Positives = 47/111 (42%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V E VPE+ D+K + F+ L V + TI + + + H
Sbjct: 87 ADLVSESVPEDPDIKGEFFEKLHGVCPERTIFTTNTSSLVPSMFAARTGRPDRFLAFH-F 145
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+P + LV+++ T E + R E IG P+ L +E G++ N +
Sbjct: 146 HPGF--KLVDVMGHAGTSAETVETVRRFAERIGHSPIVLKQEKAGYLFNSL 194
>UniRef50_Q0FMY4 Cluster: Enoyl-CoA hydratase; n=1; Roseovarius sp.
HTCC2601|Rep: Enoyl-CoA hydratase - Roseovarius sp.
HTCC2601
Length = 634
Score = 43.2 bits (97), Expect = 0.007
Identities = 34/126 (26%), Positives = 50/126 (39%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A A V V E++ +++F LD + I ++ + VI
Sbjct: 367 AAASADVVVAAVSEDMTQTQEIFSALDRICKPGAILVNNGATLDLDSIAQATRRPGDVIG 426
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H + P V L+E+V T PEV + + +QPV L DG V NR+ A
Sbjct: 427 MHFLQPDGAVRLLEVVRGARTAPEVIATVMALAPRLDKQPV-LVGVCDGLVGNRMVRAFG 485
Query: 391 DEVWRL 374
EV L
Sbjct: 486 REVQML 491
>UniRef50_Q0EXX8 Cluster: Fatty oxidation complex, alpha subunit;
n=1; Mariprofundus ferrooxydans PV-1|Rep: Fatty
oxidation complex, alpha subunit - Mariprofundus
ferrooxydans PV-1
Length = 701
Score = 43.2 bits (97), Expect = 0.007
Identities = 27/107 (25%), Positives = 48/107 (44%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V E++ +K++++ +L V +T+ + ++ H NP
Sbjct: 385 VIEAVLEDIRVKRRLWASLGKHVRKDTLLLSNTSSLSISDMQHRRANAGRIAGLHFFNPA 444
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 410
+PLVE+V T PE K + G+ P+ + E GF++NR
Sbjct: 445 PKMPLVEVVAGEKTTPETVDKVCALAVSWGKYPI-IVAESPGFLVNR 490
>UniRef50_A6UH30 Cluster: 3-hydroxybutyryl-CoA epimerase; n=2;
Sinorhizobium|Rep: 3-hydroxybutyryl-CoA epimerase -
Sinorhizobium medicae WSM419
Length = 442
Score = 43.2 bits (97), Expect = 0.007
Identities = 33/143 (23%), Positives = 58/143 (40%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A + E V E+LD+K+ VF+ + + + + ++G+ + + H
Sbjct: 124 ADLIIEAVFEDLDVKRDVFRKVAAACRHDAVLATNTSYLNPERIADGIASPERFLGLHFF 183
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
+P + L+EIVP T PE + + + PV DGF+ NRI + +
Sbjct: 184 SPAQVMKLLEIVPTGATAPEALATGFALARMLNKIPVRAGIS-DGFIGNRILKVMRGQAE 242
Query: 379 RLXXXXXXXXXXXXXVMSEGLGM 311
RL + + GL M
Sbjct: 243 RLLVTGASPSAVDAAMRAFGLPM 265
>UniRef50_O17761 Cluster: Putative uncharacterized protein ech-8;
n=4; Caenorhabditis|Rep: Putative uncharacterized
protein ech-8 - Caenorhabditis elegans
Length = 437
Score = 43.2 bits (97), Expect = 0.007
Identities = 30/119 (25%), Positives = 51/119 (42%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
+ E V E++ LKK++F LD + + I S L+ ++V+ H NP
Sbjct: 122 IVEAVFEDMKLKKELFTKLDKICKPSCIFGTNTSSLDLNEMSSVLRDPTKVVGIHFFNPA 181
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
+ +VE++ T + E I + PV L FV NR+ L++ +L
Sbjct: 182 NLIRMVEVIYGSKTSSKAVATAFEACRSIKKLPV-LVGNCPAFVFNRLLGVYLNQSQKL 239
>UniRef50_Q9L6L5 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=42; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA
hydratase/Delta(3)-cis-Delta(2)-trans-enoyl-CoA
isomerase/3- hydroxybutyryl-CoA epimerase (EC 4.2.1.17)
(EC 5.3.3.8) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)] - Salmonella typhimurium
Length = 729
Score = 43.2 bits (97), Expect = 0.007
Identities = 27/110 (24%), Positives = 45/110 (40%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V EN +KK V + V T+ + L+ H NP
Sbjct: 396 VVEAVVENPKVKKAVLAETEQKVRPETVLASNTSTIPIGELASALERPENFCGMHFFNPV 455
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQY 401
+ +PLVEI+ + E K ++G+ P+ + + GF +NR+ +
Sbjct: 456 HRMPLVEIIRGEKSSDETIAKVVAWASKMGKTPI-VVNDCPGFFVNRVLF 504
>UniRef50_Q8FRN7 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Corynebacterium efficiens|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 755
Score = 42.7 bits (96), Expect = 0.009
Identities = 31/117 (26%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSE--GLKHKSQV 578
A+ A ++ E V E+L +K F+ ++ ++ +E G +
Sbjct: 88 ALTRADWIIEAVFEDLTVKHDTFRLIEEHRSPGSLVSSNTSTIPLAQLTEVMGTPMRLDF 147
Query: 577 IVSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+ H NPP + LVE+V P T P+ A I+E+ + V R+ GF+ NRI
Sbjct: 148 AIVHFFNPPTTMRLVELVTGPDTTPKTATDLTRIIEQQLGKVVLHCRDTPGFIANRI 204
>UniRef50_Q01V22 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=1; Solibacter usitatus
Ellin6076|Rep: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor - Solibacter usitatus (strain
Ellin6076)
Length = 778
Score = 42.7 bits (96), Expect = 0.009
Identities = 27/111 (24%), Positives = 49/111 (44%), Gaps = 2/111 (1%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGL--KHKSQVIVSHPV 560
++ E V ENL++K+ ++Q + ++ I S G + + + +H
Sbjct: 89 WIVEAVAENLEIKRALWQRVAALRAPGAILSTNTSGIPLAQISAGFDSEFRRHFLGTHFF 148
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
NPP Y+ L E++P T PEV + + V ++ F+ NRI
Sbjct: 149 NPPRYLHLAEVIPGAETNPEVLDWVSSFCDLHLGKGVVRCKDTPNFIANRI 199
>UniRef50_A3T2M8 Cluster: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase;
n=4; cellular organisms|Rep: Enoyl-CoA
hydratase/isomerase/3-hydroxyacyl-CoA dehydrogenase -
Sulfitobacter sp. NAS-14.1
Length = 695
Score = 42.7 bits (96), Expect = 0.009
Identities = 27/106 (25%), Positives = 47/106 (44%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E E+ +K + L+ + TI S+GLKH ++ + H +P +
Sbjct: 371 EAAFEDFAVKTAILTELEGALPPETIIATNTSYLDVNRLSDGLKHPARFVGMHFFSPAHI 430
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+ L+E+V + T + +G+ PV L+ DGF+ NRI
Sbjct: 431 MKLLEVVRSDRTSDGTLGAALVLAHRLGKIPV-LSGVCDGFIGNRI 475
>UniRef50_Q1Z537 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Photobacterium profundum 3TCK|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Photobacterium profundum 3TCK
Length = 713
Score = 42.3 bits (95), Expect = 0.012
Identities = 25/105 (23%), Positives = 47/105 (44%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E V EN +K+ V L+ V + T+ + LK H NP +
Sbjct: 397 EAVVENPKIKEAVLAELEQVSPNATLASNTSTLMISGLA-QALKKPENFCGIHFFNPVHK 455
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 410
+PLVE++ T + + + + ++G+ P+ + + GF++NR
Sbjct: 456 MPLVEVIRGEQTSDQTITQAVKYVSQLGKTPI-VVNDCAGFLVNR 499
>UniRef50_A1SQH4 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=104; cellular organisms|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Nocardioides sp. (strain BAA-499 / JS614)
Length = 736
Score = 42.3 bits (95), Expect = 0.012
Identities = 27/112 (24%), Positives = 50/112 (44%)
Frame = -2
Query: 742 GAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHP 563
G V E V E+ LK++VF + VD + + + G+ + I H
Sbjct: 403 GCDLVIEAVFEDPSLKQQVFAEIAPYVDQDALLCSNTSTLPITELASGVDRPADFIGLHF 462
Query: 562 VNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+P +PLVEI+ T K +++++I + P+ + + GF +R+
Sbjct: 463 FSPVDKMPLVEIIRGAKTSDVALAKAYDVVQQIRKTPI-VVNDSRGFYTSRV 513
>UniRef50_A7S4Z9 Cluster: Predicted protein; n=1; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 310
Score = 42.3 bits (95), Expect = 0.012
Identities = 23/94 (24%), Positives = 42/94 (44%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV + + E ENL++KK VF+++ N + +E + + + +
Sbjct: 79 AVVNSGLIFEATIENLEVKKSVFKSISQFCRTNAVIATNTLALDTSVVAEHVTNPERCLG 138
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIME 470
+ P Y +P VEI T PE +K ++ +E
Sbjct: 139 IRFLYPVYSIPEVEITLGSQTSPETIQKVQQFLE 172
>UniRef50_Q93HI5 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=2;
Actinomycetales|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Streptomyces avermitilis
Length = 272
Score = 41.9 bits (94), Expect = 0.016
Identities = 28/109 (25%), Positives = 45/109 (41%), Gaps = 1/109 (0%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDD-NTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNP 554
V E PE+ K ++FQ LD V+D I + QV+ H NP
Sbjct: 74 VLEAAPEDEPTKLRIFQALDRAVEDPEAILATNTSALPVMRLARATDRPGQVLGLHFFNP 133
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+PLVE++ + T+ + E + + V + GFV+N +
Sbjct: 134 APVLPLVEVIGSLLTRDRTRRIAAEFATTVLGKQVVHAGDRSGFVVNAL 182
>UniRef50_Q6MM12 Cluster: Fatty oxidation complex, alpha subunit;
n=1; Bdellovibrio bacteriovorus|Rep: Fatty oxidation
complex, alpha subunit - Bdellovibrio bacteriovorus
Length = 717
Score = 41.9 bits (94), Expect = 0.016
Identities = 25/115 (21%), Positives = 50/115 (43%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E + E++ +K+KV + + I ++G H NP
Sbjct: 401 VVEAIVEDMGIKQKVIGECAGQMRPDAIIATNTSSLSVTEMAKGHPRPEYFAGMHFFNPV 460
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+PL+E++ T E E+ +++G+ PV + ++ GF++NR+ + E
Sbjct: 461 NKMPLIEVIRGEKTSDETIATIYELSKKMGKMPV-VVKDGPGFLVNRLLLPYMGE 514
>UniRef50_Q2SGR6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Hahella chejuensis KCTC 2396|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Hahella chejuensis (strain KCTC 2396)
Length = 712
Score = 41.9 bits (94), Expect = 0.016
Identities = 24/111 (21%), Positives = 47/111 (42%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V E +PE L+ K++++Q ++ + + + GL H +++ H
Sbjct: 397 ADLVLEAIPEKLEAKRQLYQEIEPRMKSDATLASNTSSIPIDELARGLAHPERLVGLHFF 456
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
NP + LVE++ T + + I + P + GF +NR+
Sbjct: 457 NPVEKMLLVEVIKGDKTSQQTLDRAMAFAALIKRVPTPV-NSAPGFFVNRV 506
>UniRef50_A5UXI1 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding precursor; n=6; Bacteria|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding precursor -
Roseiflexus sp. RS-1
Length = 807
Score = 41.9 bits (94), Expect = 0.016
Identities = 25/116 (21%), Positives = 51/116 (43%), Gaps = 2/116 (1%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVI 575
+ A ++ E + E L+ K+ + + ++ V +I + G + +
Sbjct: 97 IADADWIVEAIIEQLEPKRALMEKIEQVRKPGSIVSSNTSGIPIAAIAAGRSDDFRRHFL 156
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+H NPP Y+ L+E++P P T P+V + + V + ++ F+ NRI
Sbjct: 157 GTHFFNPPRYLYLLEVIPTPDTDPQVVAAISRFADVTLGKGVVICKDRPNFIGNRI 212
>UniRef50_A1IDF2 Cluster: 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor; n=1;
Candidatus Desulfococcus oleovorans Hxd3|Rep:
3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA
hydratase/isomerase family protein precursor -
Candidatus Desulfococcus oleovorans Hxd3
Length = 801
Score = 41.9 bits (94), Expect = 0.016
Identities = 29/111 (26%), Positives = 51/111 (45%), Gaps = 2/111 (1%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKH--KSQVIVSHPV 560
++ E V ENL +K+++F+ ++ V +I SEGL K + +H
Sbjct: 97 WIVEVVVENLKIKQQLFKRIEPVRKKGSIISSNTSGIPLKAMSEGLSSDFKQHFLGTHFF 156
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
NP Y+ L+EI+ T EV + E+ + + ++ F+ NRI
Sbjct: 157 NPVRYMHLLEIIKGEETSEEVLRFMAAFGEKRLGKGIVWAKDTPNFIGNRI 207
>UniRef50_A0VLT7 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Dinoroseobacter shibae DFL 12|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Dinoroseobacter shibae DFL 12
Length = 391
Score = 41.5 bits (93), Expect = 0.022
Identities = 23/73 (31%), Positives = 36/73 (49%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV GA++VQE VPE+L LK++V + + + I EG +V++
Sbjct: 75 AVAGAVWVQESVPEDLSLKREVVREVQA-HGPEAIVASAASDIPLEALREGAARPERVVI 133
Query: 571 SHPVNPPYYVPLV 533
+ V P Y +P V
Sbjct: 134 ARAVAPVYLLPPV 146
>UniRef50_Q0YNJ7 Cluster: 3-hydroxybutyryl-CoA dehydrogenase; n=1;
Geobacter sp. FRC-32|Rep: 3-hydroxybutyryl-CoA
dehydrogenase - Geobacter sp. FRC-32
Length = 311
Score = 41.1 bits (92), Expect = 0.029
Identities = 30/115 (26%), Positives = 50/115 (43%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A KG E + E+L LK V + + + + ++ + IV
Sbjct: 81 AAKGCDVFLEVIFEDLKLKCSVLADYLPQLPPSVVFWSNSSSLDIDPMAQAGGRPDRSIV 140
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+H +NP +P VE+VP T E + TR+ + + + P L I GF +NR+
Sbjct: 141 THGMNPVPLMPGVEVVPGAKTSSETIEFTRQTLLNMKKAPF-LAPNIPGFWVNRL 194
>UniRef50_A0LI43 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Syntrophobacter fumaroxidans MPOB|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Syntrophobacter fumaroxidans (strain DSM 10017 / MPOB)
Length = 681
Score = 41.1 bits (92), Expect = 0.029
Identities = 30/141 (21%), Positives = 60/141 (42%)
Frame = -2
Query: 733 FVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNP 554
FV E V E + +KK+V L+ ++ + + + L+ +++ H NP
Sbjct: 399 FVIEAVFEEMAVKKQVLGELEPLLRPDAVIATNTSSLSVTEMASVLRVPGRMLGFHFFNP 458
Query: 553 PYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
+PLVE++ T E ++ ++ + V L ++ F++NRI +L + L
Sbjct: 459 VAVLPLVEVIRTAQTSGEALATAFDLARKLRKTGV-LVKDAPAFLVNRILVKMLVDCLAL 517
Query: 373 XXXXXXXXXXXXXVMSEGLGM 311
+++ GL M
Sbjct: 518 VDEGASFQEVDDALLALGLPM 538
>UniRef50_A0J682 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=1; Shewanella woodyi ATCC 51908|Rep:
3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Shewanella woodyi ATCC 51908
Length = 696
Score = 41.1 bits (92), Expect = 0.029
Identities = 29/108 (26%), Positives = 49/108 (45%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E E+L++KK +F+ LD D+ I ++ QV+ H +P
Sbjct: 388 VVEAAFEDLEVKKIIFKALDQHCKDSAILATNTSYLDINSIAKVTSRPDQVVGLHFFSPA 447
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+ + L+EIV A T +V K + ++ + PV + GF NR+
Sbjct: 448 HVMKLIEIVRAENTADDVIKTMLALGVKLRKYPVEV-GVCFGFAANRM 494
>UniRef50_Q8FRT3 Cluster: Putative 3-hydroxybutyryl-CoA
dehydrogenase; n=2; Corynebacterineae|Rep: Putative
3-hydroxybutyryl-CoA dehydrogenase - Corynebacterium
efficiens
Length = 294
Score = 40.7 bits (91), Expect = 0.038
Identities = 33/119 (27%), Positives = 50/119 (42%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E VPE +DLK F+ + + I L + VI H NP
Sbjct: 101 VVEAVPEIIDLKADSFRKIAAAAPGAVIATNTSSLSVSDLA---LSVDNPVIGLHYFNPV 157
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWRL 374
LVE+V A T + RE + +G+ P+ + ++ GF +R+ AI E R+
Sbjct: 158 PASKLVEVVVADSTPEALVDLAREWVAGLGKTPI-VVKDAPGFASSRLGVAIALEAIRM 215
>UniRef50_Q47DJ5 Cluster: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-
terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding;
n=1; Dechloromonas aromatica RCB|Rep: Enoyl-CoA
hydratase/isomerase:3-hydroxyacyl-CoA dehydrogenase, C-
terminal:3-hydroxyacyl-CoA dehydrogenase, NAD-binding -
Dechloromonas aromatica (strain RCB)
Length = 705
Score = 40.7 bits (91), Expect = 0.038
Identities = 25/108 (23%), Positives = 45/108 (41%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E + ENL +K V L+ V +T+ + L+ + H NP
Sbjct: 387 VVEAIIENLKVKHAVLSELEQAVAPDTVIASNTSSLRIDEIAMPLQRPENFVGMHFFNPV 446
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+ LVE++ T + +G+ P+ + ++ GF++NRI
Sbjct: 447 PVMALVEVIKGSRTSDVAVSTAVDYAVTMGKTPI-VVQDCPGFLVNRI 493
>UniRef50_A1WHE6 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Verminephrobacter eiseniae EF01-2|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Verminephrobacter eiseniae (strain
EF01-2)
Length = 319
Score = 40.7 bits (91), Expect = 0.038
Identities = 28/114 (24%), Positives = 45/114 (39%)
Frame = -2
Query: 754 TAVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVI 575
+AV A V E VPE +K V+Q + ++ +T+ + +
Sbjct: 81 SAVASADLVIEAVPEIPQVKTSVYQQMAPLLPAHTLIATNSSTFLPSDFAAATGRPDKFC 140
Query: 574 VSHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLN 413
H N + LVEI+P T E G P+ + +E +G+VLN
Sbjct: 141 ALHYANYIWAANLVEIMPHAATARTTLDDVTRFAIETGMVPIPVGKEHNGYVLN 194
>UniRef50_Q0CYI1 Cluster: Predicted protein; n=1; Aspergillus
terreus NIH2624|Rep: Predicted protein - Aspergillus
terreus (strain NIH 2624)
Length = 192
Score = 40.7 bits (91), Expect = 0.038
Identities = 21/62 (33%), Positives = 30/62 (48%), Gaps = 2/62 (3%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEG--LKHKSQVIVSHPVN 557
V ECVPE+L LK+ + + LD TI ++G LK K +++ HP
Sbjct: 9 VVECVPESLSLKRSLLRKLDKATRPETIIASNSSSYNIPEIAKGIALKGKDRIVNMHPFL 68
Query: 556 PP 551
PP
Sbjct: 69 PP 70
>UniRef50_Q9HRI4 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
cellular organisms|Rep: 3-hydroxyacyl-CoA dehydrogenase
- Halobacterium salinarium (Halobacterium halobium)
Length = 286
Score = 40.7 bits (91), Expect = 0.038
Identities = 25/115 (21%), Positives = 53/115 (46%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E E++++K+ +F++LD + ++ + + S+V+ H +NP
Sbjct: 90 VIEAAVEDMEIKQDIFRDLDDALPEDVVLATNTSTLSITTIASVTDRASRVVGLHFMNPV 149
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+ VE+V T +V + E++ ++ + + GFV NRI ++E
Sbjct: 150 PIMTGVEVVVGEKTDADVVAFAHALAEDLDKETWE-SDDKPGFVTNRILMPWINE 203
>UniRef50_Q668V1 Cluster: Fatty acid oxidation complex subunit alpha
[Includes: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA
epimerase (EC 4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA
dehydrogenase (EC 1.1.1.35)]; n=95; Proteobacteria|Rep:
Fatty acid oxidation complex subunit alpha [Includes:
Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase (EC
4.2.1.17) (EC 5.1.2.3); 3-hydroxyacyl-CoA dehydrogenase
(EC 1.1.1.35)] - Yersinia pseudotuberculosis
Length = 753
Score = 40.7 bits (91), Expect = 0.038
Identities = 30/118 (25%), Positives = 53/118 (44%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V E+L LK+++ +++ +TI + + QVI H +P
Sbjct: 399 VVEAVFEDLSLKQQMVADIERFGAAHTIFASNTSSLPISQIAALAQRPEQVIGLHYFSPV 458
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVWR 377
+PLVE++P T E T + + G+ + + + GF +NRI ++E R
Sbjct: 459 DKMPLVEVIPHEKTSEETIATTVALARKQGKTAI-VVADRAGFYVNRILAPYINEAAR 515
>UniRef50_UPI00006A277A Cluster: UPI00006A277A related cluster; n=1;
Xenopus tropicalis|Rep: UPI00006A277A UniRef100 entry -
Xenopus tropicalis
Length = 666
Score = 40.3 bits (90), Expect = 0.050
Identities = 28/115 (24%), Positives = 49/115 (42%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E V EN+ LK+ + L +V I + + V+ H +P
Sbjct: 373 VIEAVFENMALKQDICAKLGAVAKPGAIIATNTSTLDVDVLARATGRSADVVGMHFFSPA 432
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDE 386
+ + L+E+V T P+V ++ IG+ PV ++ GF+ NR+ + E
Sbjct: 433 HVMRLLEVVRGAATAPDVLATIMKLAARIGKVPV-VSGVCYGFIGNRMAEVYMRE 486
>UniRef50_Q67QQ5 Cluster: Putative 3-hydroxyacyl-CoA dehydrogenase;
n=1; Symbiobacterium thermophilum|Rep: Putative
3-hydroxyacyl-CoA dehydrogenase - Symbiobacterium
thermophilum
Length = 190
Score = 40.3 bits (90), Expect = 0.050
Identities = 26/105 (24%), Positives = 42/105 (40%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A V E +L K+++F LDS + I + +V+
Sbjct: 78 AVADADLVIEASSVDLPGKRELFARLDSFAPAHAILATCSPTISSAYLAAATSRPDRVVS 137
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTR 437
+PP P V ++ P PEV E++ G++P+ L R
Sbjct: 138 LGFFSPPLAPPAVAVIQEPHLAPEVVAAVAEVVWRTGREPLLLRR 182
>UniRef50_A2QA05 Cluster: Catalytic activity:; n=4;
Trichocomaceae|Rep: Catalytic activity: - Aspergillus
niger
Length = 622
Score = 40.3 bits (90), Expect = 0.050
Identities = 33/125 (26%), Positives = 53/125 (42%), Gaps = 2/125 (1%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV A + E VPE L +K+ +F +L + + I L +V++
Sbjct: 87 AVATAWLIVEAVPEILPIKQSLFADLHAHSPADCILASNSSSYKSRLIGGHLPLPRRVLL 146
Query: 571 --SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYA 398
H PP + VE++ T V ++ E G PV+ +E GF+ NR+ A
Sbjct: 147 LNMHFTMPPA-IRTVELMTCGDTHERVFPMLSGVLSECGVIPVTARKESTGFIFNRLWAA 205
Query: 397 ILDEV 383
I E+
Sbjct: 206 IKREI 210
>UniRef50_A5WEP3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
NAD-binding; n=7; Proteobacteria|Rep: 3-hydroxyacyl-CoA
dehydrogenase, NAD-binding - Psychrobacter sp. PRwf-1
Length = 723
Score = 39.9 bits (89), Expect = 0.066
Identities = 25/106 (23%), Positives = 48/106 (45%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E V E++D+K +N ++V+ + I ++ K +Q I H +P
Sbjct: 407 EAVFEDIDIKAACTRNTEAVIAETAIYASNTSTLPITELAKASKRPNQFIGLHFFSPVDK 466
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+PLVEI+ T K + + +I + P+ + + GF +R+
Sbjct: 467 MPLVEIIVGEETDDATLAKGFDYVGQIAKTPI-VVNDSRGFYTSRV 511
>UniRef50_A0W3T3 Cluster: 3-hydroxybutyryl-CoA dehydrogenase
precursor; n=1; Geobacter lovleyi SZ|Rep:
3-hydroxybutyryl-CoA dehydrogenase precursor - Geobacter
lovleyi SZ
Length = 285
Score = 39.9 bits (89), Expect = 0.066
Identities = 25/124 (20%), Positives = 52/124 (41%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A+ V E + E + K ++ L +V+ I + I
Sbjct: 80 ALSDCDLVIEAIAEQMAAKCELLAELGAVLGKEAILASSTSSLSITALGAASGIPQRFIG 139
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
H +NP + LVE++ T P R+++ +G+Q V +++ GF++ R+ ++
Sbjct: 140 MHFMNPVPLMELVELIAGSETSPRTIDIARQMVTALGKQSV-CSKDQPGFIITRLLCVLI 198
Query: 391 DEVW 380
+E +
Sbjct: 199 NEAF 202
>UniRef50_Q4Q3S6 Cluster: Enoyl-CoA hydratase/Enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase, putative;
n=5; Leishmania|Rep: Enoyl-CoA hydratase/Enoyl-CoA
isomerase/3-hydroxyacyl-CoA dehydrogenase, putative -
Leishmania major
Length = 934
Score = 39.5 bits (88), Expect = 0.088
Identities = 29/122 (23%), Positives = 52/122 (42%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPV 560
A V EC PE +K+ + LDSV +TI + + QV+ H
Sbjct: 499 ADLVFECAPEVAAIKQNILAFLDSVCKRSTILATGSSAQDVNELAAVTQRPGQVLGIHFF 558
Query: 559 NPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILDEVW 380
P PLVE++ T+ V + ++ ++ + P+ L+ G+V R+ L + +
Sbjct: 559 PPANESPLVEVIRGAATERWVVELVMRLLCQLDKYPI-LSVSRHGYVGTRLLLTALYQAY 617
Query: 379 RL 374
+
Sbjct: 618 AM 619
>UniRef50_Q4DMG1 Cluster: Short chain 3-hydroxyacyl-coa
dehydrogenase, putative; n=2; Trypanosoma cruzi|Rep:
Short chain 3-hydroxyacyl-coa dehydrogenase, putative -
Trypanosoma cruzi
Length = 320
Score = 39.5 bits (88), Expect = 0.088
Identities = 25/115 (21%), Positives = 48/115 (41%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
A A + E + E++D KK +++ +D + + + +
Sbjct: 114 AASNASLIVEAILEDIDAKKVLWRKVDGMAPKECVFCTNTSSLSVGEQAAVTGRPDRFAG 173
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H +P + LVE+V A T + E + + +QPV T + GF++NR+
Sbjct: 174 LHFFSPVPMMKLVEVVKAAKTSQSTLDRILEYAKMLNKQPVMAT-DTKGFIVNRL 227
>UniRef50_Q5P5K3 Cluster: Alpha-subunit of fatty acid oxidation
complex; n=5; Betaproteobacteria|Rep: Alpha-subunit of
fatty acid oxidation complex - Azoarcus sp. (strain
EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 678
Score = 39.1 bits (87), Expect = 0.12
Identities = 23/108 (21%), Positives = 47/108 (43%)
Frame = -2
Query: 730 VQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPP 551
V E + ENLD K+ +F L+ + + L + ++++ H NP
Sbjct: 400 VIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPV 459
Query: 550 YYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
+PLVE+V + + + + + + P+ + R GF++N +
Sbjct: 460 AQMPLVEVVAGEASDADALYRAAAFVRRLDKLPLPV-RSAPGFLVNAV 506
>UniRef50_A6DTH3 Cluster: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family protein; n=1; Lentisphaera
araneosa HTCC2155|Rep: 3-hydroxyacyl-CoA dehydrogenase,
C-terminal domain family protein - Lentisphaera araneosa
HTCC2155
Length = 762
Score = 38.7 bits (86), Expect = 0.15
Identities = 26/113 (23%), Positives = 52/113 (46%), Gaps = 2/113 (1%)
Frame = -2
Query: 739 AIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKS--QVIVSH 566
A + E V E+L +K+ ++ + V + I ++ L +KS + + H
Sbjct: 85 ADLIIEAVIEDLAIKQNLWSQICKYVKADAILATNTSGLPLKDITKNLSNKSLKRFLGVH 144
Query: 565 PVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
NPP Y L+E++P P T+ + ++ E + + + ++ F+ NRI
Sbjct: 145 FFNPPRYQKLLELIPGPKTQDGLLEEFAEFARLHLGKGIVVAKDTPNFIGNRI 197
>UniRef50_Q7WIS8 Cluster: Putative enoyl-CoA isomerase; n=2;
Bordetella|Rep: Putative enoyl-CoA isomerase -
Bordetella bronchiseptica (Alcaligenes bronchisepticus)
Length = 694
Score = 38.3 bits (85), Expect = 0.20
Identities = 27/111 (24%), Positives = 47/111 (42%)
Frame = -2
Query: 724 ECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHPVNPPYY 545
E V E++ +K VF+ LD V+ I + + V+ H +P
Sbjct: 372 EAVFEDMAVKCAVFRELDRVLKPGAILGTNTSTLDVDRIAHSTRRPQDVVGLHFFSPAPV 431
Query: 544 VPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAIL 392
+PL+EIV T +V + + + + V + DGF+ NR+ + L
Sbjct: 432 MPLLEIVRGAATHADVVAAAQGLARRLRKTAV-VAGVCDGFIGNRMWHQYL 481
>UniRef50_Q0SA65 Cluster: Possible 3-hydroxybutyryl-CoA
dehydrogenase; n=1; Rhodococcus sp. RHA1|Rep: Possible
3-hydroxybutyryl-CoA dehydrogenase - Rhodococcus sp.
(strain RHA1)
Length = 331
Score = 37.9 bits (84), Expect = 0.27
Identities = 26/113 (23%), Positives = 47/113 (41%)
Frame = -2
Query: 751 AVKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIV 572
AV+ A V E V E D+K V++ + + ++T+ + +
Sbjct: 90 AVQHADLVIEAVSERPDVKTSVYETMAPHLPEHTMIATNSSTLLPQDFAAATGRPEKYCA 149
Query: 571 SHPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLN 413
H N + + VEI+ P T + E EIG PV + ++ +G+ +N
Sbjct: 150 LHFANLIWKLNAVEIMAHPETARDTLIAATEFGIEIGMVPVPIQKQQNGYAIN 202
>UniRef50_Q5LKF7 Cluster: Fatty oxidation complex, alpha subunit;
n=5; Bacteria|Rep: Fatty oxidation complex, alpha
subunit - Silicibacter pomeroyi
Length = 714
Score = 37.5 bits (83), Expect = 0.35
Identities = 24/113 (21%), Positives = 47/113 (41%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+KG + E V E +D+K V ++++ +N I + G +
Sbjct: 394 LKGCDLIIEAVFEKIDIKDAVLAEHEALLAENGIWGSNTSTLPITRLATGATRPENFVGL 453
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNR 410
H +P +PL+EI+ T E + + +I + P+ + + GF +R
Sbjct: 454 HFFSPVDKMPLLEIIAGEKTSDETLARAFDFARQIRKTPI-IVGDSTGFYTSR 505
>UniRef50_A6GC68 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=1;
Plesiocystis pacifica SIR-1|Rep: 3-hydroxyacyl-CoA
dehydrogenase - Plesiocystis pacifica SIR-1
Length = 733
Score = 37.5 bits (83), Expect = 0.35
Identities = 24/98 (24%), Positives = 40/98 (40%)
Frame = -2
Query: 742 GAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVSHP 563
G + E V ENLDLK +V + + + + I ++ H + I H
Sbjct: 412 GTDLIIEAVFENLDLKHRVTRETEPTLSADGIWASNTSAIPIGDLAKVSAHADRFIGLHY 471
Query: 562 VNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPV 449
+P +PL+EIV P T + + I + P+
Sbjct: 472 FSPVEVMPLLEIVVGPETSERTLARCLDFCRRIKKLPI 509
>UniRef50_UPI0000E4974C Cluster: PREDICTED: hypothetical protein;
n=3; Strongylocentrotus purpuratus|Rep: PREDICTED:
hypothetical protein - Strongylocentrotus purpuratus
Length = 953
Score = 37.1 bits (82), Expect = 0.47
Identities = 28/114 (24%), Positives = 47/114 (41%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
+K V E V EN+ LKK++ + LD V + I + +V+
Sbjct: 403 LKDVDVVVEAVFENMALKKEILKTLDGVCKPSAILASNTSTLDIDEMASATTRPDKVMGM 462
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRI 407
H +P + + L+E V T PE ++ + + + V L FV NR+
Sbjct: 463 HFFSPAHIMKLLENVRGKDTSPETMATAMDLGKRMKKISV-LVGNCPAFVGNRM 515
>UniRef50_Q8PMV7 Cluster: 3-hydroxyacyl-CoA dehydrogenase; n=7;
Xanthomonadaceae|Rep: 3-hydroxyacyl-CoA dehydrogenase -
Xanthomonas axonopodis pv. citri
Length = 693
Score = 37.1 bits (82), Expect = 0.47
Identities = 27/121 (22%), Positives = 50/121 (41%)
Frame = -2
Query: 748 VKGAIFVQECVPENLDLKKKVFQNLDSVVDDNTIXXXXXXXXXXXXXSEGLKHKSQVIVS 569
V A V E + EN K+ ++Q+++ + + + ++ +Q
Sbjct: 390 VTQADLVIEAIIENPQAKRDLYQSIEPQLKPDALLTTNTSSIPLTDLRGHIQRPAQFAGL 449
Query: 568 HPVNPPYYVPLVEIVPAPWTKPEVAKKTREIMEEIGQQPVSLTREIDGFVLNRIQYAILD 389
H NP +PLVEIV P + + + + PV + GF++NR+ + L
Sbjct: 450 HYFNPVAMMPLVEIVQHDGLDPANVARLAAFCKTLDKFPVPVA-GTPGFLVNRVLFPYLL 508
Query: 388 E 386
E
Sbjct: 509 E 509
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 737,325,085
Number of Sequences: 1657284
Number of extensions: 14831681
Number of successful extensions: 41271
Number of sequences better than 10.0: 267
Number of HSP's better than 10.0 without gapping: 39588
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 41208
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 62558016040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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