Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner10m18f
(640 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q4SRH5 Cluster: L-lactate dehydrogenase; n=4; Euteleost... 258 1e-67
UniRef50_P07864 Cluster: L-lactate dehydrogenase C chain; n=371;... 237 2e-61
UniRef50_UPI0000519EC7 Cluster: PREDICTED: similar to Ecdysone-i... 207 2e-52
UniRef50_P22988 Cluster: L-lactate dehydrogenase A; n=19; Magnol... 195 6e-49
UniRef50_A6NLX8 Cluster: L-lactate dehydrogenase; n=4; Eutheria|... 183 3e-45
UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11; Clostrid... 180 3e-44
UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4; Cyanobact... 179 5e-44
UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12; Bacteria... 177 2e-43
UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12; Firmic... 171 2e-41
UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6; Bacteria|... 169 6e-41
UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;... 166 5e-40
UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14; Bacill... 165 1e-39
UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9; Bacilli... 161 1e-38
UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17; Bacter... 159 7e-38
UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6; Acti... 157 2e-37
UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia ... 157 3e-37
UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1; ... 156 4e-37
UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140; Bacteri... 154 2e-36
UniRef50_Q6NPB9 Cluster: AT22132p; n=2; Drosophila melanogaster|... 152 6e-36
UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4; Thermotog... 152 8e-36
UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5; Bacillace... 151 1e-35
UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate ... 150 2e-35
UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1; Corynebac... 150 3e-35
UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2; ... 148 1e-34
UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibac... 148 1e-34
UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula... 146 3e-34
UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2; ... 144 1e-33
UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8; Lactoba... 144 1e-33
UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2; Desulfovi... 143 3e-33
UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7; Bacteria|... 142 6e-33
UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2; Bacteria|... 141 1e-32
UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13; Firmic... 138 1e-31
UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2; Propionib... 138 1e-31
UniRef50_UPI00015B6427 Cluster: PREDICTED: similar to lactate de... 134 2e-30
UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4; Lactobaci... 133 3e-30
UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28; Bacteroidet... 132 7e-30
UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2; Phaeospha... 132 9e-30
UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobu... 130 2e-29
UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;... 130 4e-29
UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizop... 130 4e-29
UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 128 8e-29
UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 127 3e-28
UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=... 126 4e-28
UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1; Ther... 126 6e-28
UniRef50_Q92BI0 Cluster: L-lactate dehydrogenase 2; n=18; Bacter... 125 8e-28
UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14; Thermoprote... 124 1e-27
UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1; Lept... 124 2e-27
UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacte... 123 4e-27
UniRef50_Q8IX04 Cluster: Ubiquitin-conjugating enzyme E2 variant... 123 4e-27
UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1; Staphyloc... 121 1e-26
UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2; Euryarchaeot... 121 2e-26
UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1; ... 120 2e-26
UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6; Mollicute... 120 4e-26
UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular org... 119 7e-26
UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3; Bifidob... 119 7e-26
UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2; Gammaproteo... 118 9e-26
UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1; Clostri... 118 9e-26
UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate dehydrog... 118 1e-25
UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD bindi... 118 1e-25
UniRef50_A1C5Q5 Cluster: L-lactate dehydrogenase; n=4; Pezizomyc... 118 2e-25
UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacte... 116 4e-25
UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4; Bacteria|... 116 4e-25
UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4; Thermoplasma... 116 4e-25
UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2; Pl... 116 5e-25
UniRef50_Q185V1 Cluster: L-lactate dehydrogenase; n=3; Clostridi... 116 5e-25
UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1; Ce... 115 8e-25
UniRef50_UPI0000DB7267 Cluster: PREDICTED: similar to Ecdysone-i... 114 2e-24
UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1; ... 114 2e-24
UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1; Lactobaci... 113 3e-24
UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|R... 113 3e-24
UniRef50_Q3U1V6 Cluster: Ubiquitin-conjugating enzyme E2 variant... 112 6e-24
UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7; Halobacteria... 112 6e-24
UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5; Gammaproteob... 112 8e-24
UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 111 1e-23
UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular or... 111 1e-23
UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3; Lactoco... 111 2e-23
UniRef50_Q8RED8 Cluster: L-lactate dehydrogenase; n=3; Fusobacte... 110 2e-23
UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:... 110 3e-23
UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 107 2e-22
UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Re... 106 4e-22
UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 105 9e-22
UniRef50_UPI000023CE12 Cluster: hypothetical protein FG10444.1; ... 105 1e-21
UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=... 105 1e-21
UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2... 104 2e-21
UniRef50_A3ZZ88 Cluster: L-lactate/malate dehydrogenase; n=1; Bl... 103 3e-21
UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomon... 102 6e-21
UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular o... 102 8e-21
UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;... 101 1e-20
UniRef50_Q92AZ3 Cluster: Lin1775 protein; n=13; Listeria|Rep: Li... 101 1e-20
UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3; Acti... 101 1e-20
UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1; Asp... 101 1e-20
UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex ae... 101 2e-20
UniRef50_Q6YPG1 Cluster: Putative uncharacterized protein OJA121... 100 3e-20
UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1; Cand... 100 3e-20
UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12; Ca... 100 3e-20
UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasm... 99 4e-20
UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17; Apicompl... 100 6e-20
UniRef50_O26290 Cluster: Malate dehydrogenase; n=2; Methanobacte... 99 8e-20
UniRef50_Q4A0K7 Cluster: Lactate dehydrogenase; n=1; Staphylococ... 98 2e-19
UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3; Eimeriorina... 98 2e-19
UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;... 97 4e-19
UniRef50_Q03ZZ4 Cluster: Enzyme with possible activities of L-2-... 96 5e-19
UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene en... 96 7e-19
UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3; Methanomi... 96 7e-19
UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like prot... 95 2e-18
UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4; Epsilonprote... 94 3e-18
UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;... 93 5e-18
UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium ... 93 5e-18
UniRef50_Q1FMY2 Cluster: L-lactate dehydrogenase; n=1; Clostridi... 91 2e-17
UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|R... 91 2e-17
UniRef50_Q04GC4 Cluster: Enzyme with possible activities of L-2-... 88 1e-16
UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1; ... 87 3e-16
UniRef50_Q38YI2 Cluster: Putative malate dehydrogenase; n=1; Lac... 87 4e-16
UniRef50_Q6LZI3 Cluster: Malate dehydrogenase; n=5; Methanococcu... 86 6e-16
UniRef50_Q0P989 Cluster: L-lactate dehydrogenase; n=10; Campylob... 85 1e-15
UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter... 84 2e-15
UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 84 3e-15
UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1; Propionib... 83 5e-15
UniRef50_P14295 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 83 7e-15
UniRef50_Q88ZG9 Cluster: L-2-hydroxyisocaproate dehydrogenase; n... 81 3e-14
UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6; Plasmodi... 81 3e-14
UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasm... 80 4e-14
UniRef50_Q2FPC3 Cluster: Lactate/malate dehydrogenase; n=2; Meth... 78 2e-13
UniRef50_Q034P5 Cluster: Enzyme with possible activities of L-2-... 77 3e-13
UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 77 4e-13
UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;... 77 5e-13
UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH - ... 74 3e-12
UniRef50_Q6ABQ3 Cluster: L-lactate dehydrogenase; n=1; Propionib... 72 1e-11
UniRef50_Q82R06 Cluster: Putative lactate dehydrogenase; n=1; St... 71 2e-11
UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4; Bacteroidale... 67 4e-10
UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5; Bacteroidale... 63 6e-09
UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1... 63 6e-09
UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1; Meth... 60 6e-08
UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2; Mycoplasm... 58 1e-07
UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1; ... 58 1e-07
UniRef50_Q1U8H4 Cluster: L-lactate dehydrogenase; n=2; Lactobaci... 57 4e-07
UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3; Le... 56 5e-07
UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=... 53 7e-06
UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa ... 47 3e-04
UniRef50_Q8Y860 Cluster: Lmo1057 protein; n=11; Listeria|Rep: Lm... 45 0.002
UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;... 41 0.022
UniRef50_Q039N1 Cluster: Malate/lactate dehydrogenase; n=1; Lact... 41 0.022
UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular org... 41 0.022
UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep: A... 40 0.067
UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5; Protostomia|... 39 0.088
UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=12... 39 0.088
UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces cere... 38 0.27
UniRef50_Q0JBC2 Cluster: Os04g0542900 protein; n=8; Magnoliophyt... 37 0.36
UniRef50_UPI0000DB7CDC Cluster: PREDICTED: similar to CTD (carbo... 37 0.47
UniRef50_Q2QQV8 Cluster: Retrotransposon protein, putative, uncl... 36 0.62
UniRef50_Q1WU75 Cluster: Lactate/malate dehydrogenase; n=1; Lact... 36 0.82
UniRef50_Q08W33 Cluster: Serine/threonine-protein kinase Pkn6; n... 35 1.4
UniRef50_Q03QL8 Cluster: Malate/lactate dehydrogenase; n=1; Lact... 35 1.9
UniRef50_Q7G3D9 Cluster: Retrotransposon protein, putative, uncl... 35 1.9
UniRef50_UPI0000E45EC5 Cluster: PREDICTED: similar to CG10662-PA... 34 2.5
UniRef50_A0QSN0 Cluster: Ftsk/spoiiie family protein; n=1; Mycob... 34 2.5
UniRef50_A2YRW8 Cluster: Putative uncharacterized protein; n=2; ... 34 2.5
UniRef50_Q8EYH1 Cluster: Methyl-accepting chemotaxis protein; n=... 34 3.3
UniRef50_A0W7C0 Cluster: Diguanylate cyclase/phosphodiesterase w... 34 3.3
UniRef50_A1S187 Cluster: UBA/THIF-type NAD/FAD binding protein; ... 34 3.3
UniRef50_UPI000155BE55 Cluster: PREDICTED: similar to CENPE vari... 33 4.4
UniRef50_Q15ST6 Cluster: UBA/THIF-type NAD/FAD binding fold; n=2... 33 4.4
UniRef50_Q9VQF9 Cluster: CG9958-PA, isoform A; n=2; Sophophora|R... 33 4.4
UniRef50_Q45614 Cluster: Sensor protein yycG; n=34; Bacillales|R... 33 4.4
UniRef50_Q55GH1 Cluster: Putative uncharacterized protein; n=1; ... 33 5.8
UniRef50_Q6NYY8 Cluster: Smox protein; n=12; Coelomata|Rep: Smox... 33 7.7
UniRef50_Q8FY97 Cluster: Prephenate dehydrogenase; n=75; Bacteri... 33 7.7
UniRef50_Q6ANF8 Cluster: Related to dipeptidase; n=17; Bacteria|... 33 7.7
UniRef50_Q577J1 Cluster: Alcohol dehydrogenase, zinc-containing;... 33 7.7
UniRef50_Q15QV8 Cluster: Putative uncharacterized protein; n=1; ... 33 7.7
UniRef50_A6EYX5 Cluster: Sensor protein; n=1; Marinobacter algic... 33 7.7
UniRef50_Q6ZCA3 Cluster: Putative uncharacterized protein P0547A... 33 7.7
UniRef50_Q74ZH8 Cluster: AGR229Wp; n=2; Eremothecium gossypii|Re... 33 7.7
UniRef50_Q4P6B5 Cluster: Putative uncharacterized protein; n=1; ... 33 7.7
>UniRef50_Q4SRH5 Cluster: L-lactate dehydrogenase; n=4;
Euteleostomi|Rep: L-lactate dehydrogenase - Tetraodon
nigroviridis (Green puffer)
Length = 360
Score = 258 bits (631), Expect = 1e-67
Identities = 119/188 (63%), Positives = 157/188 (83%), Gaps = 1/188 (0%)
Frame = +1
Query: 79 LKKLFQPVHEKVDET-WSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMM 255
L+KL P+ + E +KVT+VGVGQVGMA A S+L +++ + +ALVD+M D+LKGE+M
Sbjct: 5 LQKLISPLADSPSEPPRNKVTVVGVGQVGMACAISILLRDLADELALVDVMEDRLKGELM 64
Query: 256 DLQHGSAFMRNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQ 435
DLQHGS F++ +KI + DYS+TA S++ VVTAGVRQ+EGESRL+LVQRN +V K IIPQ
Sbjct: 65 DLQHGSLFLKTSKIVADKDYSVTANSRLVVVTAGVRQQEGESRLNLVQRNVNVFKSIIPQ 124
Query: 436 LIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATT 615
+IKYSP+ L++ SNPVD+LTYVTWK+SGLPKHRVIGSGTNLDSARFRYL+++RLGI +
Sbjct: 125 IIKYSPNCTLIVVSNPVDVLTYVTWKLSGLPKHRVIGSGTNLDSARFRYLMAERLGIHAS 184
Query: 616 SCHGYIIG 639
S +G+++G
Sbjct: 185 SFNGWVLG 192
>UniRef50_P07864 Cluster: L-lactate dehydrogenase C chain; n=371;
Eukaryota|Rep: L-lactate dehydrogenase C chain - Homo
sapiens (Human)
Length = 332
Score = 237 bits (579), Expect = 2e-61
Identities = 109/186 (58%), Positives = 143/186 (76%)
Frame = +1
Query: 82 KKLFQPVHEKVDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDL 261
++L + + E + + K+TIVG G VGMA A S+L +++ + +ALVD+ DKLKGEMMDL
Sbjct: 6 EQLIEKLIEDDENSQCKITIVGTGAVGMACAISILLKDLADELALVDVALDKLKGEMMDL 65
Query: 262 QHGSAFMRNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLI 441
QHGS F +KI S DYS++A S+I +VTAG RQ+EGE+RL LVQRN ++K IIP ++
Sbjct: 66 QHGSLFFSTSKITSGKDYSVSANSRIVIVTAGARQQEGETRLALVQRNVAIMKSIIPAIV 125
Query: 442 KYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSC 621
YSPD +++ SNPVDILTY+ WKISGLP RVIGSG NLDSARFRYL+ ++LG+ TSC
Sbjct: 126 HYSPDCKILVVSNPVDILTYIVWKISGLPVTRVIGSGCNLDSARFRYLIGEKLGVHPTSC 185
Query: 622 HGYIIG 639
HG+IIG
Sbjct: 186 HGWIIG 191
>UniRef50_UPI0000519EC7 Cluster: PREDICTED: similar to
Ecdysone-inducible gene L3 CG10160-PA; n=2;
Apocrita|Rep: PREDICTED: similar to Ecdysone-inducible
gene L3 CG10160-PA - Apis mellifera
Length = 409
Score = 207 bits (505), Expect = 2e-52
Identities = 95/178 (53%), Positives = 134/178 (75%)
Frame = +1
Query: 106 EKVDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR 285
E V + KVT+VG G VG+A +++ Q +T ++A+VD KL+GE MD HG + +
Sbjct: 90 EPVQDCCHKVTVVGSGMVGVAIVNALIFQKITAHVAMVDAFPKKLEGEGMDYCHGLSLIE 149
Query: 286 NAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTIL 465
+ +I TD+ IT+ SK+ V+ AG RQ +GESRLDLVQRN+++LK IIP L+ YSP+ ++
Sbjct: 150 SPRIDFDTDFCITSNSKVIVLAAGARQMKGESRLDLVQRNSEILKSIIPTLVGYSPNAVI 209
Query: 466 VIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
++ SNPVDIL+++TWKISGLP RVIG+GT++DSARFR+L++DRLGIA +S H IIG
Sbjct: 210 LVVSNPVDILSWLTWKISGLPASRVIGTGTHVDSARFRFLIADRLGIAPSSVHATIIG 267
>UniRef50_P22988 Cluster: L-lactate dehydrogenase A; n=19;
Magnoliophyta|Rep: L-lactate dehydrogenase A - Hordeum
vulgare (Barley)
Length = 356
Score = 195 bits (476), Expect = 6e-49
Identities = 86/171 (50%), Positives = 128/171 (74%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
+K++++G G VGMA A ++LTQN+ + IALVD + DKL+GE +DLQH +AF+ +I S
Sbjct: 44 TKISVIGAGNVGMAIAQTILTQNLADEIALVDALPDKLRGEALDLQHAAAFLPRVRI-SG 102
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
TD ++T S + +VTAG RQ GE+RL+L+QRN + ++I+P + ++SPD +L++ SNPV
Sbjct: 103 TDAAVTKNSDLVIVTAGARQIPGETRLNLLQRNVALYRKIVPPVAEHSPDALLLVVSNPV 162
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D+LTYV WK+SG P RVIGSGTNLDS+RFR+L+++ L + Y++G
Sbjct: 163 DVLTYVAWKLSGFPASRVIGSGTNLDSSRFRFLIAEHLDVNAQDVQAYMVG 213
>UniRef50_A6NLX8 Cluster: L-lactate dehydrogenase; n=4;
Eutheria|Rep: L-lactate dehydrogenase - Homo sapiens
(Human)
Length = 253
Score = 183 bits (446), Expect = 3e-45
Identities = 84/170 (49%), Positives = 119/170 (70%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
KV+I G G VGMA A S+L + +++ +A VD+ KLKGE MDLQH S FM+ + I S
Sbjct: 71 KVSITGTGSVGMACATSILLKGLSDELAFVDLDEGKLKGETMDLQHDSPFMKMSNIVCSK 130
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
DY +TA + ++TAG R+ +GE R +LV++N + K +I +++ SP L+I SNPVD
Sbjct: 131 DYLVTANPHLVIITAGARREKGEMRFNLVRQNVAIFKLMISSIVQQSPLCKLIIVSNPVD 190
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
ILTYV WK+S PK+RVIGSG NLD+ RF++ + +LGI + SC G+I+G
Sbjct: 191 ILTYVAWKLSAFPKNRVIGSGCNLDTVRFQFFIGQKLGIHSESCRGWILG 240
>UniRef50_Q8XP62 Cluster: L-lactate dehydrogenase; n=11;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
perfringens
Length = 317
Score = 180 bits (437), Expect = 3e-44
Identities = 80/176 (45%), Positives = 124/176 (70%)
Frame = +1
Query: 112 VDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA 291
+ E +K++I+G G VG AF+++ + + I +VD+ DK E MDL G+AF+++
Sbjct: 2 IREKTNKISIIGAGFVGSTTAFALMQDGLASEIVIVDINKDKAHAEAMDLAQGAAFVKSV 61
Query: 292 KIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVI 471
I+S DY+ T S I ++TAGV + GE+RLD++ +N + + I+P+++KYSP++IL++
Sbjct: 62 DIKSG-DYADTKDSDIVIITAGVGPKPGETRLDIINKNLKIFQSIVPEVVKYSPNSILLV 120
Query: 472 ASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
SNPVDILTY+T+K+SG PK RVIGSGT LD++R +Y+LS+ I + H YIIG
Sbjct: 121 VSNPVDILTYITYKLSGFPKERVIGSGTVLDTSRLKYMLSEHFDIDARNVHTYIIG 176
>UniRef50_Q7NG49 Cluster: L-lactate dehydrogenase; n=4;
Cyanobacteria|Rep: L-lactate dehydrogenase - Gloeobacter
violaceus
Length = 330
Score = 179 bits (436), Expect = 5e-44
Identities = 86/170 (50%), Positives = 122/170 (71%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K IVG G VGMA A+SML QN + + LVD+ K++GE+MDL HG F+ + +++ T
Sbjct: 22 KGAIVGAGAVGMAIAYSMLIQNTFDELVLVDIDRRKVEGEVMDLVHGIPFVEPSVVRAGT 81
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+ G + V+TAG RQREGE+RL LVQRN ++ + +I +++++ P+ IL++ SNPVD
Sbjct: 82 -LADCRGVDVVVITAGARQREGETRLSLVQRNVEIFRGLIGEIMEHCPNAILLVVSNPVD 140
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
++TYV K++GLP RVIGSGT LD+ARFRYLL++RL + S H YIIG
Sbjct: 141 VMTYVAMKLAGLPPSRVIGSGTVLDTARFRYLLAERLRVDPRSLHAYIIG 190
>UniRef50_Q892U0 Cluster: L-lactate dehydrogenase; n=12;
Bacteria|Rep: L-lactate dehydrogenase - Clostridium
tetani
Length = 316
Score = 177 bits (431), Expect = 2e-43
Identities = 80/170 (47%), Positives = 120/170 (70%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K++I+G G VG A++++ + + + I +VD+ +K KGE MDL HG +F++ I +
Sbjct: 7 KISIIGSGFVGSTTAYALMMEGLASEIVIVDINKEKAKGEAMDLSHGVSFVKPVDIIAG- 65
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
DY T S I ++TAG + GE+RLDL+ +N ++ K I+P+++KYSP +IL++ SNPVD
Sbjct: 66 DYEDTKDSDIVIITAGAGPKPGETRLDLINKNYEIFKGIVPEVVKYSPKSILLVVSNPVD 125
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
ILTYVT+K+SG P+ RVIGSGT LD++RFRYLL + I + H YI+G
Sbjct: 126 ILTYVTYKLSGFPQERVIGSGTVLDTSRFRYLLGEHFKIDVRNVHTYILG 175
>UniRef50_Q81K80 Cluster: L-lactate dehydrogenase 2; n=12;
Firmicutes|Rep: L-lactate dehydrogenase 2 - Bacillus
anthracis
Length = 314
Score = 171 bits (415), Expect = 2e-41
Identities = 84/171 (49%), Positives = 112/171 (65%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
++V +VG G VG + A+SM+ Q V LVD+ K +GE MDL H F + S
Sbjct: 6 NRVVLVGTGAVGCSYAYSMINQGVAEEFVLVDVNEAKAEGEAMDLSHAVPFSPSPTKVWS 65
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
Y+ + + V+TAG+ Q+ GE+RLDLV++NT + KQI+ ++ D I +IA+NPV
Sbjct: 66 GSYADCKDADLVVITAGLPQKPGETRLDLVEKNTKIFKQIVRGIMDSGFDGIFLIATNPV 125
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DILTYVTWK SGLPK RVIGSGT LDSARFRY+L D L + + H YI+G
Sbjct: 126 DILTYVTWKESGLPKERVIGSGTTLDSARFRYMLGDYLDVDPRNVHAYIVG 176
>UniRef50_Q1IRL5 Cluster: L-lactate dehydrogenase; n=6;
Bacteria|Rep: L-lactate dehydrogenase - Acidobacteria
bacterium (strain Ellin345)
Length = 321
Score = 169 bits (410), Expect = 6e-41
Identities = 77/170 (45%), Positives = 116/170 (68%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
++ +VG+G VG + AF++L + + I L+D K +GE MDL H F +I +
Sbjct: 12 RIAVVGLGNVGASFAFALLQRRLAAEIVLIDANHKKAEGEAMDLNHAVPFGAATRIWAG- 70
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+Y+ G+ + V+TAG QR GE+RL L+ RN + +QI+P+++K++PD +L+IA+NPVD
Sbjct: 71 EYADCRGAAVTVITAGAAQRPGETRLQLLDRNLAIFQQIVPEVVKHNPDGLLLIATNPVD 130
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
I++Y ++KISGLP HRV+GSGT LD+ARFRYLL + S HG I+G
Sbjct: 131 IISYASYKISGLPAHRVLGSGTILDTARFRYLLGQHFSVDARSVHGLILG 180
>UniRef50_A3DCA4 Cluster: L-lactate dehydrogenase precursor; n=2;
Clostridium|Rep: L-lactate dehydrogenase precursor -
Clostridium thermocellum (strain ATCC 27405 / DSM 1237)
Length = 318
Score = 166 bits (403), Expect = 5e-40
Identities = 79/171 (46%), Positives = 112/171 (65%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
SKV I+G G VG +AAF+M + N + L+D+ +K GE MD+ HG FM + +
Sbjct: 8 SKVAIIGAGFVGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMSLYAG 67
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
DYS + VVTAG ++ GE+RLDL ++N + K++ ++KY ++++ SNPV
Sbjct: 68 -DYSDVKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPV 126
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DI+TY+ K SGLP +VIGSGT LDS RFRYLLS++LG+ + HGYIIG
Sbjct: 127 DIITYMIQKWSGLPVGKVIGSGTVLDSIRFRYLLSEKLGVDVKNVHGYIIG 177
>UniRef50_P20619 Cluster: L-lactate dehydrogenase X; n=14;
Bacillales|Rep: L-lactate dehydrogenase X - Bacillus
psychrosaccharolyticus
Length = 319
Score = 165 bits (400), Expect = 1e-39
Identities = 77/171 (45%), Positives = 109/171 (63%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
++V ++G G VG + AF++L Q++T + ++D+ DK G+ MDL HG F N
Sbjct: 7 NRVALIGAGSVGSSYAFALLNQSITEELVIIDVNEDKAMGDAMDLNHGKIFAPNPTKTWY 66
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
+Y + I + AG Q+ GE+RLDLV++N + K ++ Q++ D I +IA+NPV
Sbjct: 67 GNYDDCKEADIVCICAGANQKPGETRLDLVEKNLKIFKSLVDQVMASGFDGIFLIATNPV 126
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DILTY TWK SGLPK RVIGSGT LDS RFR+LL + IA + H +IIG
Sbjct: 127 DILTYATWKFSGLPKERVIGSGTILDSGRFRFLLGEYFDIAPANVHAHIIG 177
>UniRef50_Q838C9 Cluster: L-lactate dehydrogenase 2; n=9;
Bacilli|Rep: L-lactate dehydrogenase 2 - Enterococcus
faecalis (Streptococcus faecalis)
Length = 317
Score = 161 bits (392), Expect = 1e-38
Identities = 83/171 (48%), Positives = 111/171 (64%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAF-MRNAKIQSS 306
KV I+G G VG + A+SM+ Q + N + LVD+ K +GE +DL G ++ N + +
Sbjct: 7 KVAIIGTGFVGTSIAYSMINQGIANELILVDIDKAKSEGEAIDLLDGVSWGQENVNVWAG 66
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
DY + I V+TAG Q+ G+SRLDLV N +++K I+ ++K D ILVIASNPV
Sbjct: 67 -DYQDCQDADIVVITAGANQKPGQSRLDLVSINAEIMKTIVNNIMKSGFDGILVIASNPV 125
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D+LTYV W+ SGLP RVIG+GT LD+ RFR LS RL I + HGYIIG
Sbjct: 126 DVLTYVAWQASGLPVSRVIGTGTTLDTTRFRKELSQRLAIDPRNVHGYIIG 176
>UniRef50_P19869 Cluster: L-lactate dehydrogenase 2; n=17;
Bacteria|Rep: L-lactate dehydrogenase 2 -
Bifidobacterium longum
Length = 320
Score = 159 bits (385), Expect = 7e-38
Identities = 69/171 (40%), Positives = 113/171 (66%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
+K+ ++G G VG AF+ + + I L D+ ++++ E++D+QHGS+F I S
Sbjct: 9 TKLAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDGS 68
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
D I + + V+TAG RQ+ G+SRL+LV ++LK I+P L+K +P+ I ++ +NPV
Sbjct: 69 DDPEICRDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPV 128
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DI T+V K++GLP++++ GSGTNLDSAR R+L++ + G+ + H YI G
Sbjct: 129 DIATHVAQKLTGLPENQIFGSGTNLDSARLRFLIAQQTGVNVKNVHAYIAG 179
>UniRef50_A1U9V0 Cluster: Lactate/malate dehydrogenase; n=6;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 329
Score = 157 bits (382), Expect = 2e-37
Identities = 72/181 (39%), Positives = 112/181 (61%)
Frame = +1
Query: 97 PVHEKVDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA 276
P +V KV+I+G G VG A A++ L + +AL D + K++ E++DL HGS
Sbjct: 9 PASPEVRSARPKVSIIGAGSVGTAIAYACLIRGSAGTLALYDTNSAKVRAEVLDLNHGSQ 68
Query: 277 FMRNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPD 456
F+ ++ S D ++TAGS I VVTAG +Q G+SRLDL N + + + PQL+++SPD
Sbjct: 69 FVPECRVGGSDDIAVTAGSAIVVVTAGAKQHPGQSRLDLAAANVAMAQTLTPQLLEHSPD 128
Query: 457 TILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYII 636
+++ +NPVD++TY + ++ G+GT LDS+RFRYL++ R IA + H +I
Sbjct: 129 AVVIFVTNPVDVVTYAASSVVDAQPGQIFGTGTVLDSSRFRYLVAQRAAIAVGNVHALVI 188
Query: 637 G 639
G
Sbjct: 189 G 189
>UniRef50_O51114 Cluster: L-lactate dehydrogenase; n=4; Borrelia
burgdorferi group|Rep: L-lactate dehydrogenase -
Borrelia burgdorferi (Lyme disease spirochete)
Length = 316
Score = 157 bits (380), Expect = 3e-37
Identities = 76/173 (43%), Positives = 113/173 (65%), Gaps = 2/173 (1%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQN-VTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQ 300
+KV ++G G VG + A+++ N + + + ++D+ +K KGE+MDL HG F++ N +
Sbjct: 5 NKVVLIGAGGVGSSFAYALTIDNSLVHELVIIDVNENKAKGEVMDLNHGQMFLKKNINVL 64
Query: 301 SSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
T Y A + I V+TAG+ Q+ GE+RLDLV +N+ + K II ++ D I V+ASN
Sbjct: 65 FGT-YKDCANADIVVITAGLNQKPGETRLDLVDKNSKIFKDIITNVVSSGFDGIFVVASN 123
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
PVDI+TYVT K S P H+VIG+GT LD++R RY LSD + T + H YI+G
Sbjct: 124 PVDIMTYVTMKYSKFPIHKVIGTGTILDTSRLRYFLSDHFNVNTQNIHSYIMG 176
>UniRef50_A4QXM2 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 323
Score = 156 bits (379), Expect = 4e-37
Identities = 73/171 (42%), Positives = 109/171 (63%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
KV IVG G VG A+++L I L+D+ DK +GE+MDL H + F+ +I +
Sbjct: 14 KVVIVGAGYVGSTTAYTLLMNRAAAEIVLIDVDKDKTEGEVMDLVHAAPFLHQTRIWAG- 72
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKY-SPDTILVIASNPV 486
DY G+ + ++TAG Q+ G+SR++L Q N + K+I+P+++++ SPD +L++++NPV
Sbjct: 73 DYEDCKGASVIILTAGANQKPGQSRMELAQSNWGIFKEIVPKVVQHASPDALLLVSANPV 132
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D++TY K SG P H VIGSGT+LDSARF L L I S H +IG
Sbjct: 133 DVMTYAAVKFSGFPAHSVIGSGTSLDSARFAGELGKHLNIDPRSLHAVVIG 183
>UniRef50_P0A3M9 Cluster: L-lactate dehydrogenase; n=140;
Bacteria|Rep: L-lactate dehydrogenase - Streptococcus
pneumoniae
Length = 328
Score = 154 bits (373), Expect = 2e-36
Identities = 75/172 (43%), Positives = 113/172 (65%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDM--MADKLKGEMMDLQHGSAFMRNAKIQS 303
KV +VG G VG + AF+++ Q + + ++++ + +K G+ +DL H AF KI +
Sbjct: 9 KVILVGDGAVGSSYAFALVNQGIAQELGIIEIPQLHEKAVGDALDLSHALAFTSPKKIYA 68
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
+ YS A + + V+TAG Q+ GE+RLDLV +N + K I+ Q+++ I ++A+NP
Sbjct: 69 A-QYSDCADADLVVITAGAPQKPGETRLDLVGKNLAINKSIVTQVVESGFKGIFLVAANP 127
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VD+LTY TWK SG PK RVIGSGT+LDSARFR L+++L + S H YI+G
Sbjct: 128 VDVLTYSTWKFSGFPKERVIGSGTSLDSARFRQALAEKLDVDARSVHAYIMG 179
>UniRef50_Q6NPB9 Cluster: AT22132p; n=2; Drosophila
melanogaster|Rep: AT22132p - Drosophila melanogaster
(Fruit fly)
Length = 361
Score = 152 bits (369), Expect = 6e-36
Identities = 69/186 (37%), Positives = 118/186 (63%), Gaps = 1/186 (0%)
Frame = +1
Query: 85 KLFQPVHEKVDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQ 264
K +P+ E SK+++VG GQVG A + +L +N+T N+ ++D+ + K E +D Q
Sbjct: 35 KSMRPMKEFKRPRISKISVVGAGQVGTAISAMLLLRNLTKNLVILDINYELAKAEALDFQ 94
Query: 265 HGSAFMRNAKIQSSTDYSITAGSKICVVTAGVRQR-EGESRLDLVQRNTDVLKQIIPQLI 441
H SAF+ +A++ D + + S + ++TAG R + SRL +Q+ ++LK+ +P+L+
Sbjct: 95 HASAFLSDARVVPCGDSTNSKDSDVVIITAGARPSGKDRSRLAAMQKTVEILKKAVPKLV 154
Query: 442 KYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSC 621
+ SP+ +I SNP D++TY +I+ LPKHR +G +LD+ RFR L+++RL + +
Sbjct: 155 ELSPNATFIIISNPADVMTYAVQRITNLPKHRCFTTGCHLDTVRFRNLIANRLRLPPSQV 214
Query: 622 HGYIIG 639
HGY+IG
Sbjct: 215 HGYVIG 220
>UniRef50_P16115 Cluster: L-lactate dehydrogenase; n=4;
Thermotogaceae|Rep: L-lactate dehydrogenase - Thermotoga
maritima
Length = 319
Score = 152 bits (368), Expect = 8e-36
Identities = 72/170 (42%), Positives = 111/170 (65%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ IVG+G+VG + AF++L + + L+D+ + +G+ +DL HG+ F R A I +
Sbjct: 2 KIGIVGLGRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANIYAG- 60
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
DY+ GS + +V AGV Q+ GE+RL L+ RN V+K+I + KY+PD+I+++ +NPVD
Sbjct: 61 DYADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTNPVD 120
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+LTY K SG+ +V GSGT LD+AR R L++ G + S H Y+IG
Sbjct: 121 VLTYFFLKESGMDPRKVFGSGTVLDTARLRTLIAQHCGFSPRSVHVYVIG 170
>UniRef50_Q8ELF0 Cluster: L-lactate dehydrogenase; n=5;
Bacillaceae|Rep: L-lactate dehydrogenase -
Oceanobacillus iheyensis
Length = 321
Score = 151 bits (366), Expect = 1e-35
Identities = 72/171 (42%), Positives = 108/171 (63%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
++V ++G G VG++ AF+++ Q VT +A++D+ ADK G++MDL HG AF +
Sbjct: 9 NRVVLIGGGSVGVSYAFALMNQGVTEELAIIDLDADKALGDVMDLNHGKAFAPSLTNVWL 68
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
+Y + I + AG Q+ GE+RLDLV++N + K+I+ ++ + I +IA+NPV
Sbjct: 69 GEYGDCKDADIVCICAGANQQSGETRLDLVEKNMKIFKEIVTDVMNSGFNGIFLIATNPV 128
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DILT SGLP HRVIGSGT LD+AR RY L + ++ + H YIIG
Sbjct: 129 DILTQAVISFSGLPPHRVIGSGTTLDTARLRYELGEYFHLSPKNIHAYIIG 179
>UniRef50_UPI0000DB7268 Cluster: PREDICTED: similar to L-lactate
dehydrogenase A chain (LDH-A) (LDH muscle subunit)
(LDH-M); n=2; Apis mellifera|Rep: PREDICTED: similar to
L-lactate dehydrogenase A chain (LDH-A) (LDH muscle
subunit) (LDH-M) - Apis mellifera
Length = 348
Score = 150 bits (364), Expect = 2e-35
Identities = 67/175 (38%), Positives = 110/175 (62%)
Frame = +1
Query: 112 VDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA 291
VD K+ IVG G G+A ++L + + + + +D+ + K E D+ HG+AF+ N
Sbjct: 28 VDGHRVKIVIVGSGYTGVAIGIAILFKRLASELVFIDVNEELAKAEAEDISHGAAFLGNP 87
Query: 292 KIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVI 471
KI + DYS+ + +CV+T G R + L+++N ++ K +IP++ KY+P++IL+I
Sbjct: 88 KIIGTKDYSLARDATVCVITIGDRSTNEQDPSTLLEQNLNIFKDVIPKVCKYAPNSILLI 147
Query: 472 ASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYII 636
+ PVDIL+Y K+SG P HRV+G GT LDS RF+Y ++ +LGI+ +S +I
Sbjct: 148 VTAPVDILSYAAMKLSGFPPHRVVGLGTFLDSCRFQYFIAQKLGISASSVQASVI 202
>UniRef50_Q4JY42 Cluster: L-lactate dehydrogenase; n=1;
Corynebacterium jeikeium K411|Rep: L-lactate
dehydrogenase - Corynebacterium jeikeium (strain K411)
Length = 326
Score = 150 bits (363), Expect = 3e-35
Identities = 71/172 (41%), Positives = 109/172 (63%), Gaps = 1/172 (0%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQS 303
SK+ ++G G VG+A A++++ Q +T+++A++D+ K G + DL H + N ++
Sbjct: 16 SKIVLIGAGDVGIAYAYTLVNQGLTDHLAIIDLDERKTWGHVQDLNHAVPWSHHNTRVTV 75
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
T + +C+ AG Q+ GE+RLDLV +NT + K I+ ++ + + I ++ASNP
Sbjct: 76 GTYEDCRDAAMVCIC-AGAAQKPGETRLDLVAKNTAIFKTIVGDVMSHGFNGIFLVASNP 134
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VDIL+Y TWK SG+ RVIGSGT LD+ARFRY L +A TS H Y+IG
Sbjct: 135 VDILSYATWKFSGMDSSRVIGSGTILDTARFRYALGRYFDLAPTSVHAYVIG 186
>UniRef50_Q9P7P7 Cluster: Probable L-lactate dehydrogenase; n=2;
Ascomycota|Rep: Probable L-lactate dehydrogenase -
Schizosaccharomyces pombe (Fission yeast)
Length = 330
Score = 148 bits (359), Expect = 1e-34
Identities = 69/170 (40%), Positives = 105/170 (61%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ IVG G VG AF++L + I ++D+ K +GE MDL H + ++
Sbjct: 22 KIVIVGAGNVGSTTAFTLLLSGLAAEIVIIDLNKKKAEGEAMDLNHAAPLSHETRVYLG- 80
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
DY + V+TAG Q+ GE+R+DL++ N + K+I+ ++ KY+ D IL++A+NPVD
Sbjct: 81 DYKDCKDATAVVITAGKNQKPGETRMDLLKANISIFKEILREVTKYTKDAILLVATNPVD 140
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+LTY T K++G P RVIGSGT +D+ARF+YL+ G+ S + IIG
Sbjct: 141 VLTYATLKLTGFPAERVIGSGTIIDTARFQYLIGKLYGLDPQSVNADIIG 190
>UniRef50_Q2S4R2 Cluster: L-lactate dehydrogenase; n=1; Salinibacter
ruber DSM 13855|Rep: L-lactate dehydrogenase -
Salinibacter ruber (strain DSM 13855)
Length = 316
Score = 148 bits (358), Expect = 1e-34
Identities = 72/170 (42%), Positives = 112/170 (65%), Gaps = 1/170 (0%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTD 312
V IVG G VG AAA++M Q++ + I L+D + +GE MDL HG + ++ +
Sbjct: 7 VGIVGTGNVGTAAAYAMFNQSLASEILLLDQDTRRAEGEAMDLMHGQQLVGGITCRA-VE 65
Query: 313 YSITAGSKICVVTAGVRQRE-GESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
Y+ + ++I V++AG Q+ E+RL L+QRN ++ ++II QL K++P+ ILV+A+NPVD
Sbjct: 66 YAALSNAQIIVLSAGASQQSPDETRLGLLQRNAEIFREIIIQLDKHAPNAILVVATNPVD 125
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+LTY+ ++S P R++G+GT LD+ARFR LL G+ S H YI+G
Sbjct: 126 VLTYICQELSSRPNRRILGTGTLLDTARFRALLGRHYGVDPRSVHAYILG 175
>UniRef50_A3JXA9 Cluster: L-lactate dehydrogenase; n=1; Sagittula
stellata E-37|Rep: L-lactate dehydrogenase - Sagittula
stellata E-37
Length = 300
Score = 146 bits (355), Expect = 3e-34
Identities = 72/161 (44%), Positives = 106/161 (65%)
Frame = +1
Query: 157 VGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTDYSITAGSK 336
VG AAAF+ + + V + I LVD+ + + E D+ H F +A+I + Y +G+
Sbjct: 2 VGSAAAFACIMRGVASEIVLVDLDTARAQAEAEDIAHAVPFSVSARIVAG-GYDDLSGAD 60
Query: 337 ICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKI 516
+ ++ GV Q+ GESRL+L+ RN +V + ++ + + +PD IL+IASNPVDI+T+VT +
Sbjct: 61 VVILACGVSQKPGESRLELLSRNAEVFRAVVGDVTRAAPDAILLIASNPVDIMTHVTQAL 120
Query: 517 SGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
SGLP RVIGSGT LD+ARFR+LL L IA S H Y++G
Sbjct: 121 SGLPAGRVIGSGTILDTARFRWLLGRHLNIAPRSVHAYVLG 161
>UniRef50_A5KJY5 Cluster: Putative uncharacterized protein; n=2;
Ruminococcus|Rep: Putative uncharacterized protein -
Ruminococcus torques ATCC 27756
Length = 316
Score = 144 bits (350), Expect = 1e-33
Identities = 67/170 (39%), Positives = 110/170 (64%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K ++G G VG A++++ + + + + L+D K +GE MD+ HG F I +
Sbjct: 6 KAAVIGCGFVGSTIAYTLMQKGLFSEMVLLDANKAKAEGEAMDISHGLPFTHAMDIYAG- 64
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+Y A + + ++TAG Q+ GE+RLDLVQ+N +++ II ++ + + + IL+I SNPVD
Sbjct: 65 EYEDIADASVVIITAGANQKPGETRLDLVQKNAAIMRSIIKEIKRVNCEGILLIVSNPVD 124
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
ILT V + SG PK RVIGSGT LD+AR +Y++S++L + + + H +I+G
Sbjct: 125 ILTEVALRESGFPKERVIGSGTVLDTARLKYIISEKLDVDSRNVHAFIVG 174
>UniRef50_P59390 Cluster: L-lactate dehydrogenase 2; n=8;
Lactobacillus|Rep: L-lactate dehydrogenase 2 -
Lactobacillus plantarum
Length = 309
Score = 144 bits (350), Expect = 1e-33
Identities = 71/176 (40%), Positives = 114/176 (64%)
Frame = +1
Query: 112 VDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA 291
+D+ KV IVG G VG + AFS++ + + +VD++ +G++ DL+ +AF
Sbjct: 1 MDKKQRKVVIVGDGSVGSSFAFSLVQNCALDELVIVDLVKTHAEGDVKDLEDVAAFTNAT 60
Query: 292 KIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVI 471
I + +Y+ + I V+TAGV ++ GESRLDL+ RNT +L+ I+ ++ + VI
Sbjct: 61 NIHTG-EYADARDADIVVITAGVPRKPGESRLDLINRNTKILESIVKPVVASGFNGCFVI 119
Query: 472 ASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+SNPVDILT +T ++SG P+HRVIG+GT+LD+AR R L+ +L +ATT+ ++G
Sbjct: 120 SSNPVDILTSMTQRLSGFPRHRVIGTGTSLDTARLRVALAQKLNVATTAVDAAVLG 175
>UniRef50_P62051 Cluster: L-lactate dehydrogenase; n=2;
Desulfovibrio vulgaris subsp. vulgaris|Rep: L-lactate
dehydrogenase - Desulfovibrio vulgaris (strain
Hildenborough / ATCC 29579 / NCIMB8303)
Length = 309
Score = 143 bits (347), Expect = 3e-33
Identities = 69/171 (40%), Positives = 112/171 (65%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
+++ ++GVG VGMA A++ + + N+I L+D A + +GE MDL A + +I+S
Sbjct: 2 NRIAVIGVGNVGMAFAYAAAIKRLANDIVLIDANAARAEGESMDLADAMALVGPVQIRSG 61
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
Y G++I VVTAG +Q G+SRLDLV+ N + + I+ +++Y+ D + ++A+NPV
Sbjct: 62 -GYEQCEGARIVVVTAGAKQMPGQSRLDLVRVNAGITRDILTAVMQYADDPLYIMATNPV 120
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D+LT+V ++G+ RVIGSGT LDSARFR +++ LG+ H +I+G
Sbjct: 121 DVLTHVARTVTGVAPGRVIGSGTVLDSARFRGHVAEILGVDVRGVHAHIVG 171
>UniRef50_P50933 Cluster: L-lactate dehydrogenase; n=7;
Bacteria|Rep: L-lactate dehydrogenase - Deinococcus
radiodurans
Length = 304
Score = 142 bits (344), Expect = 6e-33
Identities = 65/170 (38%), Positives = 110/170 (64%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
KV +VG G VG AAF+++ + + + LVD D+ + E D+ H + ++
Sbjct: 2 KVGVVGTGFVGSTAAFALVLRGSCSELVLVDRDEDRAQAEAEDIAHAAPVSHGTRVWHG- 60
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+S A +++ ++TAG Q+ GESRLDL+++N D+ ++++PQ+ + +PD +L++ SNPVD
Sbjct: 61 GHSELADAQVVILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLVTSNPVD 120
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+LT + +++ P VIGSGT LDSARFR+L++ G+ T HGY++G
Sbjct: 121 LLTDLATQLA--PGQPVIGSGTVLDSARFRHLMAQHAGVDGTHAHGYVLG 168
>UniRef50_P62056 Cluster: L-lactate dehydrogenase; n=2;
Bacteria|Rep: L-lactate dehydrogenase - Treponema
denticola
Length = 315
Score = 141 bits (341), Expect = 1e-32
Identities = 75/178 (42%), Positives = 106/178 (59%), Gaps = 2/178 (1%)
Frame = +1
Query: 112 VDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA 291
+DE KVT+VG G VG A+++ + IA+ DM + +G+ +DL G F+
Sbjct: 1 MDEKKRKVTVVGAGAVGSTFAYALAQSGYADEIAITDMNKNFAEGQALDLVQGLPFLPQV 60
Query: 292 KIQSS--TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTIL 465
I + TDY A S I VVTAG +Q+ GE+R+DL++RN ++ I + + ++
Sbjct: 61 DIHAGDKTDY---ADSDIVVVTAGAKQQSGETRIDLLKRNASIITGIAKDIAESGCSGVM 117
Query: 466 VIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+I SNPVDILT K SG + RVIGSGT LD+ARFRY LS G+ + HGYI+G
Sbjct: 118 LIVSNPVDILTRAALKASGWERGRVIGSGTVLDTARFRYTLSKECGVDARNIHGYILG 175
>UniRef50_Q81XJ7 Cluster: L-lactate dehydrogenase 3; n=13;
Firmicutes|Rep: L-lactate dehydrogenase 3 - Bacillus
anthracis
Length = 316
Score = 138 bits (334), Expect = 1e-31
Identities = 64/170 (37%), Positives = 104/170 (61%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ I+G G VG + A+S++ Q + + L+D+ ++ GE MDL H F +
Sbjct: 7 KIAIIGTGLVGSSCAYSIVNQGICEELLLIDINHERAVGEAMDLSHCINFTNTRTKVYAG 66
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
Y I ++TAG + G+SRLD + + +++ ++ +++ D I ++ASNPVD
Sbjct: 67 SYEDCKDMDIVIITAGPAPKPGQSRLDTLGASAKIMESVVGGVMESGFDGIFLLASNPVD 126
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
I+TY WK+SGLP++RVIG+GT+LDS+R R +LS+ L + S HGY +G
Sbjct: 127 IITYQVWKLSGLPRNRVIGTGTSLDSSRLRTILSEMLHVDPRSIHGYSLG 176
>UniRef50_Q6A9C3 Cluster: L-lactate dehydrogenase; n=2;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 319
Score = 138 bits (333), Expect = 1e-31
Identities = 63/171 (36%), Positives = 105/171 (61%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
SK+++VG G VG + A++ L + ++L D+ DK++ E+ DL HG+ F A +
Sbjct: 11 SKISVVGAGSVGSSLAYACLIRGSAGLVSLYDIAKDKVEAEVADLAHGTQFTP-ASVMGG 69
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
D TA S + +TAG RQ+ G++RLDL N ++L+ ++PQL++ SP+ + V+ +NP
Sbjct: 70 ADVHDTADSDVVFITAGARQKPGQTRLDLAGVNANILRSLMPQLVEQSPNALFVLVTNPC 129
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D+LT V + +GLP +RV +GT LD++R R+L+ + H I+G
Sbjct: 130 DVLTVVAQEATGLPANRVFSTGTMLDTSRLRWLIRQWANVEQRHVHATIVG 180
>UniRef50_UPI00015B6427 Cluster: PREDICTED: similar to lactate
dehydrogenase; n=1; Nasonia vitripennis|Rep: PREDICTED:
similar to lactate dehydrogenase - Nasonia vitripennis
Length = 352
Score = 134 bits (324), Expect = 2e-30
Identities = 60/170 (35%), Positives = 107/170 (62%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
+K+ IVG G VG+A A +L + + + L+D + + E D+ + F+ + KI++S
Sbjct: 38 TKIVIVGSGPVGVAVAVGLLFKRLAAELILMDENPEMARAEAEDIAAAAVFLGSPKIRAS 97
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
TDYS + +CV+ AG +QR+ ++Q+N +LK+++P L KY+P+++L++ S PV
Sbjct: 98 TDYSEARDATLCVIAAGRQQRDEADAEAVLQQNALLLKELVPSLTKYAPNSVLLVVSEPV 157
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYII 636
D+L+++ K+SG P RV+G GT LD+ R ++ L+ LG+ + H +I
Sbjct: 158 DVLSHLAMKLSGFPSQRVLGLGTLLDNCRLQHELAKELGVNQAAVHSMVI 207
>UniRef50_A4L2P0 Cluster: L-lactate dehydrogenase; n=4;
Lactobacillus|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri
Length = 312
Score = 133 bits (322), Expect = 3e-30
Identities = 72/171 (42%), Positives = 103/171 (60%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSML-TQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
KV ++G G VG + AFS L + N + + LVD K G+ DL + KI +
Sbjct: 8 KVVLIGDGAVGSSFAFSFLQSTNEVDELVLVDRTKSKAVGDAADLADITPLTNPVKIYAG 67
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
T Y A + + V+TAG+ ++ GE+RLDLV +NT +LK II ++K + VI+SNPV
Sbjct: 68 T-YEDAADADVVVITAGIPRKPGETRLDLVNKNTTILKSIIKPIVKSGFTGVFVISSNPV 126
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DILT + +ISG PK RVIG+GT+LDS R R LLS +L ++ ++G
Sbjct: 127 DILTTIAQRISGFPKERVIGTGTSLDSMRLRVLLSKKLHLSVNVIDALMLG 177
>UniRef50_Q64P62 Cluster: Malate dehydrogenase; n=28;
Bacteroidetes|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 313
Score = 132 bits (319), Expect = 7e-30
Identities = 64/173 (36%), Positives = 102/173 (58%), Gaps = 2/173 (1%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR--NAKIQ 300
SKVT+VG G VG A + V + + ++D+ +G+ MD+ + + +
Sbjct: 2 SKVTVVGAGNVGATCANVLAFNEVADEVVMLDVKEGVSEGKAMDMMQTAQLLGFDTTIVG 61
Query: 301 SSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
+ DY+ TA S + V+T+G+ ++ G +R +L+ N ++K + L+KYSP+ I+V+ SN
Sbjct: 62 CTNDYAQTANSDVVVITSGIPRKPGMTREELIGVNAGIVKSVAENLLKYSPNAIIVVISN 121
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
P+D +TY+ K GLPK+RVIG G LDS+RF+Y LS LG G +IG
Sbjct: 122 PMDTMTYLALKSLGLPKNRVIGMGGALDSSRFKYFLSQALGCNANEVEGMVIG 174
>UniRef50_Q0UX88 Cluster: L-lactate dehydrogenase; n=2;
Phaeosphaeria nodorum|Rep: L-lactate dehydrogenase -
Phaeosphaeria nodorum (Septoria nodorum)
Length = 326
Score = 132 bits (318), Expect = 9e-30
Identities = 62/169 (36%), Positives = 107/169 (63%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTD 312
+ ++G G VG A++++ Q++ + LVD L G++ DL ++ R+ K++S T
Sbjct: 10 IAVIGCGDVGATLAYTLILQSICTEVLLVDPKTSLLDGQVRDLSDATS--RSTKVRSGT- 66
Query: 313 YSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDI 492
+ + I V+TAG +Q+ GESRL L+ RN ++L I + S T+L++ +NPVDI
Sbjct: 67 HQEAGQADIVVITAGAKQKTGESRLSLLTRNLNILSSIFDSMKPISAHTVLLLVANPVDI 126
Query: 493 LTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
L Y +SGLP+++V+G+GT+LDSAR R +L+ + G++ +S Y++G
Sbjct: 127 LVYFARMMSGLPENQVLGTGTSLDSARLRGVLAGKAGVSPSSIDAYVLG 175
>UniRef50_O08349 Cluster: Malate dehydrogenase; n=1; Archaeoglobus
fulgidus|Rep: Malate dehydrogenase - Archaeoglobus
fulgidus
Length = 294
Score = 130 bits (315), Expect = 2e-29
Identities = 61/151 (40%), Positives = 97/151 (64%), Gaps = 1/151 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSS 306
K+ VG G+VG +AF+ L + IALVD+ D GE MDL H +A + + KI
Sbjct: 2 KLGFVGAGRVGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIVGG 61
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
DYS+ GS+I VVTAG+ ++ G +RLDL +N ++K I ++++ +P++ +++ +NP+
Sbjct: 62 ADYSLLKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTNPM 121
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFR 579
D++TY+ WK SG P++ V G G LDS R +
Sbjct: 122 DVMTYIMWKESGKPRNEVFGMGNQLDSQRLK 152
>UniRef50_Q1FID3 Cluster: L-lactate dehydrogenase precursor; n=1;
Clostridium phytofermentans ISDg|Rep: L-lactate
dehydrogenase precursor - Clostridium phytofermentans
ISDg
Length = 325
Score = 130 bits (313), Expect = 4e-29
Identities = 61/171 (35%), Positives = 104/171 (60%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
SKV +VG G VG + AFS++TQ+V + + L+D+ K GE+MDL H ++ + +
Sbjct: 8 SKVIVVGAGLVGTSTAFSLITQSVCDEVMLIDINRAKAHGEVMDLCHSIEYLNRNVLVTE 67
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
DY+ + I V+TAG + G+SRLD + + D++ I+ ++K + I ++ +NPV
Sbjct: 68 GDYTDCKDADIVVITAGPPPKPGQSRLDTLGLSADIVSTIVEPVMKSGFNGIFLVVTNPV 127
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D + +++SGLPK +V+G+GT +DSAR ++ + D L + S Y +G
Sbjct: 128 DSIAQYVYQLSGLPKQQVLGTGTAIDSARLKHFIGDILHVDPRSIQAYTMG 178
>UniRef50_Q9P4B6 Cluster: L-lactate dehydrogenase A; n=48; Rhizopus
oryzae|Rep: L-lactate dehydrogenase A - Rhizopus oryzae
(Rhizopus delemar)
Length = 320
Score = 130 bits (313), Expect = 4e-29
Identities = 65/171 (38%), Positives = 104/171 (60%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
SKV IVG G VG + A++++ +N+ I +VD+ D ++ +++DL ++ S
Sbjct: 5 SKVAIVGAGAVGASTAYALMFKNICTEIIIVDVNPDIVQAQVLDLADAASISHTPIRAGS 64
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
+ + A I V+TAG +QREGE R L++RN VL+ II + PD ++++ +NPV
Sbjct: 65 AEEAGQAD--IVVITAGAKQREGEPRTKLIERNFRVLQSIIGGMQPIRPDAVILVVANPV 122
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DILT++ +SGLP ++VIGSGT LD+ R R L D + S H +++G
Sbjct: 123 DILTHIAKTLSGLPPNQVIGSGTYLDTTRLRVHLGDVFDVNPQSVHAFVLG 173
>UniRef50_Q98PG4 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
pulmonis|Rep: L-lactate dehydrogenase - Mycoplasma
pulmonis
Length = 315
Score = 128 bits (310), Expect = 8e-29
Identities = 61/172 (35%), Positives = 105/172 (61%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAF--MRNAKIQS 303
KV ++G G VG+ ++M+T+ + L+D+ + KG MD+ A +KI++
Sbjct: 3 KVVLIGTGNVGVTVVYTMITKGIDAEYVLIDINTEFAKGHAMDMSDAIALNSTTGSKIRT 62
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
T Y+ G+ + +V AG Q++GE+RL+++ N+ ++K I ++ K + ++ SNP
Sbjct: 63 GT-YADAKGADLLIVAAGRPQKQGETRLEMIADNSKIMKDIALEIKKSGFNGFTIVISNP 121
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VDIL V K++ PK +V+ SGT LD++RFR LS++ G+ T S HG++IG
Sbjct: 122 VDILATVFQKVTNFPKEKVMSSGTFLDTSRFRKFLSEKTGVPTNSVHGFVIG 173
>UniRef50_A6M0Q2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
beijerinckii NCIMB 8052|Rep: L-lactate dehydrogenase -
Clostridium beijerinckii NCIMB 8052
Length = 316
Score = 127 bits (306), Expect = 3e-28
Identities = 61/171 (35%), Positives = 100/171 (58%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
SKV IVG G VG A AF M+ +V +++ L+D+ +K E DLQH + +
Sbjct: 6 SKVVIVGTGSVGAAVAFDMVMNHVCDDLILIDINKEKSWAEATDLQHSLGYSGSKMRVKD 65
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
+Y + I V+ A + G++RLD++++ ++ I+P ++K I+V+ +NPV
Sbjct: 66 GEYEECNDADIVVIAAALPYITGQTRLDMLEKAAGIMNNIVPNIMKSGFSGIIVVITNPV 125
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D+++Y K+SGLP +VIG+GT LDSAR +Y L+D + + S H +G
Sbjct: 126 DVMSYYVHKLSGLPASKVIGTGTALDSARLKYHLADVMSVDPQSVHALCMG 176
>UniRef50_Q18WQ6 Cluster: Malate dehydrogenase, NAD-dependent; n=2;
Desulfitobacterium hafniense|Rep: Malate dehydrogenase,
NAD-dependent - Desulfitobacterium hafniense (strain
DCB-2)
Length = 320
Score = 126 bits (304), Expect = 4e-28
Identities = 60/174 (34%), Positives = 107/174 (61%), Gaps = 3/174 (1%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADK--LKGEMMDLQHGSAFMRNA-KI 297
+K++++G G G AF ML +I L+D A++ KG+ +D+ R++ ++
Sbjct: 2 AKISVIGSGFTGTTTAF-MLAMKGLGDIVLLDTQANENPTKGKALDIMEAGPLTRSSVRV 60
Query: 298 QSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIAS 477
++DY T S + V+TAG+ ++ G SR +L N ++ ++ Q++++SP++ L+I S
Sbjct: 61 TGTSDYQDTLDSDVVVITAGIARKPGMSRNELCDINAGIVTHVVRQVVQHSPNSTLIILS 120
Query: 478 NPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
NPVDI+TYV +K SG ++R+IG LDSARFRY ++ L ++ G+++G
Sbjct: 121 NPVDIMTYVAFKESGFKRNRIIGQSGVLDSARFRYFVASELKVSAEDVTGFVLG 174
>UniRef50_A1HSK3 Cluster: Lactate/malate dehydrogenase; n=1;
Thermosinus carboxydivorans Nor1|Rep: Lactate/malate
dehydrogenase - Thermosinus carboxydivorans Nor1
Length = 303
Score = 126 bits (303), Expect = 6e-28
Identities = 60/170 (35%), Positives = 104/170 (61%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ IVG G+VG A ++ + + + + I +VD DK GE +D+ AF A+I+
Sbjct: 2 KIAIVGSGKVGAAIGYTAMLKGLAHEIVMVDAARDKAHGEALDMLQCLAFAPPARIRHG- 60
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+ + TAG+ I V+TAG+ ++ E R+ L+ RN ++ ++ Q + YSP+ I+ + +NP+D
Sbjct: 61 EMADTAGADIVVITAGIPRKADEPRVLLLSRNAALIADLVRQAVHYSPNCIIFMVTNPLD 120
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
++T + +++SGLP +RVIG GT LD+AR+R L+ Y++G
Sbjct: 121 VMTQLAYQVSGLPANRVIGMGTVLDTARYRSYLAVAFDADARDIDAYVVG 170
>UniRef50_Q92BI0 Cluster: L-lactate dehydrogenase 2; n=18;
Bacteria|Rep: L-lactate dehydrogenase 2 - Listeria
innocua
Length = 311
Score = 125 bits (302), Expect = 8e-28
Identities = 64/171 (37%), Positives = 102/171 (59%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
KV I+G G VG AAA + + Q + LVD+ ++++G DL +AFM S
Sbjct: 5 KVMIIGAGNVGSAAAHAFVNQKFVEELILVDLNKERVEGNRKDLADAAAFMSGKMDISVR 64
Query: 310 DYSITAGSKICVVTAGVRQ-REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
+ S A I V+T +EG++RLD ++ + ++ I+P+++K I +IA+NP
Sbjct: 65 EASDCADVDIAVITVTAGPLKEGQTRLDELRSTSRIVASIVPEMMKGGFKGIFLIATNPC 124
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DI+TY WK+SGLP+ +V+G+G LD+ R R LL+++L IA S +I+G
Sbjct: 125 DIITYQVWKLSGLPREQVLGTGVWLDTTRLRRLLAEKLDIAAQSIDAFILG 175
>UniRef50_Q8ZVB2 Cluster: Malate dehydrogenase; n=14;
Thermoprotei|Rep: Malate dehydrogenase - Pyrobaculum
aerophilum
Length = 309
Score = 124 bits (300), Expect = 1e-27
Identities = 59/170 (34%), Positives = 104/170 (61%), Gaps = 1/170 (0%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSST 309
+TI+G G+VG AAA M + N I L+D++ +GE +D+ H S+ + + + S
Sbjct: 2 ITIIGSGRVGTAAAVIMGLMKLDNKILLIDIVKGLPQGEALDMNHMSSILGLDVEYVGSN 61
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+Y GS + +VTAG+ ++ G +R L++ N ++ +I ++ KY+PD+I+++ +NP+D
Sbjct: 62 EYKDIEGSDLIIVTAGLPRKPGMTREQLLEANAKIVAEIGREIKKYAPDSIVILTTNPLD 121
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+TYV WK +G P+ RVIG LD+ R + + +LGI+ S ++G
Sbjct: 122 AMTYVMWKATGFPRERVIGFSGVLDAGRLAFYAAKKLGISPASILPIVLG 171
>UniRef50_A3EWH3 Cluster: Malate/lactate dehydrogenase; n=1;
Leptospirillum sp. Group II UBA|Rep: Malate/lactate
dehydrogenase - Leptospirillum sp. Group II UBA
Length = 320
Score = 124 bits (298), Expect = 2e-27
Identities = 56/171 (32%), Positives = 105/171 (61%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMD-LQHGSAFMRNAKIQSS 306
KV+IVG G VG A + +N ++ ++D+ +G+ +D L+ G + +I S
Sbjct: 8 KVSIVGAGNVGATTA-QKIVENGLADVVILDVREGMAQGKALDILESGPLLGFDTRIVGS 66
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
+Y GS + VVTAG ++ G SR DL+ +N D++ ++ ++ K++PD+++++ +NP+
Sbjct: 67 GNYETIEGSSVVVVTAGFSRKPGMSREDLLHKNGDIMIEVAEKIRKHAPDSVVIMVTNPM 126
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D++ Y+ WK++G P+ RVIG G LDS+RF Y +S+ + ++ ++G
Sbjct: 127 DLMAYILWKVTGFPRERVIGMGGALDSSRFAYFVSEVTNTSVSNIQTMVMG 177
>UniRef50_A0RPE9 Cluster: Malate dehydrogenase; n=1; Campylobacter
fetus subsp. fetus 82-40|Rep: Malate dehydrogenase -
Campylobacter fetus subsp. fetus (strain 82-40)
Length = 306
Score = 123 bits (296), Expect = 4e-27
Identities = 57/171 (33%), Positives = 98/171 (57%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSS 306
K+ I+G G VG + A ++++ V + L+D+ + + MDL +A + + I
Sbjct: 2 KIAIIGAGNVGASCASLLISRKVCKKVTLIDINKNLAIAKAMDLAQMAAVLNLDIDIFGG 61
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
+Y + I V+TAG +++G+SR DL N ++ + K++P +I+++ +NP+
Sbjct: 62 DNYELLKDFDIVVITAGFARKDGQSRDDLAMMNAKIVSHSSKMVSKFAPKSIIIVVTNPL 121
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DI+ YV +K SG +H+VIG LDSARFRY +S +LG+ C G +G
Sbjct: 122 DIMVYVAFKESGFARHKVIGMAGELDSARFRYYMSQKLGLNVAQCFGKCVG 172
>UniRef50_Q8IX04 Cluster: Ubiquitin-conjugating enzyme E2 variant 3;
n=15; Euteleostomi|Rep: Ubiquitin-conjugating enzyme E2
variant 3 - Homo sapiens (Human)
Length = 471
Score = 123 bits (296), Expect = 4e-27
Identities = 62/175 (35%), Positives = 108/175 (61%)
Frame = +1
Query: 115 DETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAK 294
++T +K+T+VG G++G+A ++ + + + + L+D+ ++ KG MDL+
Sbjct: 179 NKTVNKITVVGGGELGIACTLAISAKGIADRLVLLDL-SEGTKGATMDLE----IFNLPN 233
Query: 295 IQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIA 474
++ S D S +A SK+ + T +S LD+VQ N D+ + ++P L YS ++L++A
Sbjct: 234 VEISKDLSASAHSKVVIFTVN-SLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVA 292
Query: 475 SNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
S PV+I+TYVTWK+S P +RVIG G NLDS R +Y++++ L T+ ++IG
Sbjct: 293 SQPVEIMTYVTWKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTSGKEVWVIG 347
>UniRef50_Q4L941 Cluster: L-lactate dehydrogenase; n=1;
Staphylococcus haemolyticus JCSC1435|Rep: L-lactate
dehydrogenase - Staphylococcus haemolyticus (strain
JCSC1435)
Length = 318
Score = 121 bits (292), Expect = 1e-26
Identities = 58/170 (34%), Positives = 100/170 (58%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ ++G G VG A A +++ + + + +A++D+ DK K ++ DL H + F N
Sbjct: 5 KIVLIGSGYVGSAFAHAIVAKGLVDEMAIIDIDEDKAKADVWDLNHATPFGDNFVNVHVG 64
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
Y + I V+ A + +GE+RL L++ N D+ +I +++ D V+ SNPVD
Sbjct: 65 QYEDFKDADIVVICASAKLAKGETRLKLLEDNVDIFVPMIQRIVDSGFDGYFVLPSNPVD 124
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
I++YV ++S PK+++IGSGT+LD+ARF++ LS +A + IIG
Sbjct: 125 IMSYVVKRVSNFPKNKIIGSGTSLDTARFQFFLSREFDVAPNQVYAPIIG 174
>UniRef50_Q8TWG5 Cluster: Malate dehydrogenase; n=2;
Euryarchaeota|Rep: Malate dehydrogenase - Methanopyrus
kandleri
Length = 317
Score = 121 bits (291), Expect = 2e-26
Identities = 62/175 (35%), Positives = 106/175 (60%), Gaps = 4/175 (2%)
Frame = +1
Query: 127 SKVTIVGV-GQVGMAAAFSMLTQNVTNNIALV--DMMADKLKGEMMDLQHG-SAFMRNAK 294
SKV ++G G+VG AA + + N + L+ DKL+G D+ +A ++A+
Sbjct: 2 SKVAVIGATGRVGSTAAARLALLDCVNEVTLIARPKSVDKLRGLRRDILDSLAAAQKDAE 61
Query: 295 IQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIA 474
I + + + V+TAG+ ++ G++RLDL + N ++K+ + + + +P+ I+++
Sbjct: 62 ITIGCERDDYVDADVIVMTAGIPRKPGQTRLDLTKDNAAIIKKYLEGVAEENPEAIVLVV 121
Query: 475 SNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+NPVD+LTYV K+SGLPK+RVIG GT+LDS RF+ L++ + + H IIG
Sbjct: 122 TNPVDVLTYVALKVSGLPKNRVIGLGTHLDSMRFKVLIAKHFNVHMSEVHTRIIG 176
>UniRef50_Q5B0T8 Cluster: Putative uncharacterized protein; n=1;
Emericella nidulans|Rep: Putative uncharacterized
protein - Emericella nidulans (Aspergillus nidulans)
Length = 237
Score = 120 bits (290), Expect = 2e-26
Identities = 60/160 (37%), Positives = 99/160 (61%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
S++ IVGVGQVG AAA++++ ++ + + LVD A G++ DL + R+ S
Sbjct: 8 SRIAIVGVGQVGAAAAYALVLGSIADELLLVDTRAAWRDGQVRDLSDAAYASRSKTRVYS 67
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
Y + I V+TAG + G++ +D + RNT +++ II ++ + DT+L+I +NPV
Sbjct: 68 ATYREASQCDIVVITAGSKYLYGQTSMDYLYRNTSIVRSIINEMKPFRSDTVLLIVANPV 127
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGI 606
D++T + ++S LP +V+GSGT LDS R R LL+D G+
Sbjct: 128 DLMTSLAKELSNLPSAQVLGSGTFLDSIRLRGLLADETGV 167
>UniRef50_Q6F0L9 Cluster: L-lactate dehydrogenase; n=6;
Mollicutes|Rep: L-lactate dehydrogenase - Mesoplasma
florum (Acholeplasma florum)
Length = 317
Score = 120 bits (288), Expect = 4e-26
Identities = 61/174 (35%), Positives = 101/174 (58%)
Frame = +1
Query: 118 ETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKI 297
+T +KV +VG G VGM+ +S + Q + L+D+ +G +D+Q A +
Sbjct: 3 KTSNKVVLVGTGAVGMSFIYSAVNQGLAEEYVLIDVNTKAAEGNAIDIQDTMAVLDKPFT 62
Query: 298 QSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIAS 477
+ Y + + V+TAG QR GE+RL+L+ N+ ++K I + + + VIAS
Sbjct: 63 IKAGTYEDCKDADLIVITAGRPQRPGETRLELIADNSRIMKGIAEAIKASGFNGVTVIAS 122
Query: 478 NPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
NP D+LT V +++G +H V+G+GT LDSAR R L++++L +A S + YI+G
Sbjct: 123 NPCDVLTTVYQQVTGYDEHSVVGAGTTLDSARLRRLVAEKLNVAPKSVNAYIMG 176
>UniRef50_Q3ZZJ7 Cluster: Malate dehydrogenase; n=5; cellular
organisms|Rep: Malate dehydrogenase - Dehalococcoides
sp. (strain CBDB1)
Length = 307
Score = 119 bits (286), Expect = 7e-26
Identities = 56/171 (32%), Positives = 102/171 (59%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDL-QHGSAFMRNAKIQSS 306
K++++G G VG A ++ ++ + + ++D++ +G+ +D+ Q S I S
Sbjct: 3 KISVIGAGNVGATLAQRLIEKDFAD-VVMLDVVEGIPQGKALDISQSASVLGFRHTITGS 61
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
DY+ TAGS+I V+TAG+ ++ G +R +L+ N ++ ++ +KYSP+ LV+ SNPV
Sbjct: 62 NDYAQTAGSEIVVITAGIARKPGMTREELLAINQKIMTDVVSNCLKYSPEATLVVVSNPV 121
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D +TY+ WK+SGLP+ RV+G LD R ++ LG+ ++ ++G
Sbjct: 122 DTMTYLAWKLSGLPRKRVVGLSGVLDGGRLATFVARELGVNPSAVSPCVMG 172
>UniRef50_P59050 Cluster: L-lactate dehydrogenase 1; n=3;
Bifidobacterium longum|Rep: L-lactate dehydrogenase 1 -
Bifidobacterium longum
Length = 316
Score = 119 bits (286), Expect = 7e-26
Identities = 57/172 (33%), Positives = 102/172 (59%), Gaps = 1/172 (0%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQS 303
+KV IVG GQVG AAF ++T + N + L+D A K GE DL GS F R+ K+++
Sbjct: 7 NKVVIVGTGQVGATAAFGIVTHGLCNELVLIDCSAAKALGEARDLDDGSEFQDRHVKVRA 66
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
DY+ + I V+T G + +R+ + ++ +++ ++ D ++V+ SNP
Sbjct: 67 G-DYADCKDADIVVITVGRKPPANSNRMAELGFTVGLVGEVVDNVMASGFDGVIVMVSNP 125
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VD++ + WK SGLP+ +V+G+GT LD++R + ++ + G+ + G+++G
Sbjct: 126 VDVMAWYAWKRSGLPRTQVLGTGTALDTSRLKTIIGEETGLDPRNVGGFVMG 177
>UniRef50_A4BB89 Cluster: Lactate dehydrogenase; n=2;
Gammaproteobacteria|Rep: Lactate dehydrogenase -
Reinekea sp. MED297
Length = 319
Score = 118 bits (285), Expect = 9e-26
Identities = 56/172 (32%), Positives = 100/172 (58%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA--FMRNAKIQS 303
K+ ++G G VG+ L + + L+D K +GEMMD H ++ F +N ++++
Sbjct: 2 KIGVIGAGAVGVGVCHYTLAFGSCSELVLIDQQIGKAEGEMMDFGHANSLTFSKNIRLRA 61
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
DYS+ + I V+TAG + +EG++R DL + N+ + I ++ +P+ IL++ +NP
Sbjct: 62 GDDYSLLTDADIVVITAGAQIKEGQTRDDLAEINSRITVDIAQKIETVAPNAILLVVTNP 121
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DI TY + +G P RVI +G +D+AR L+S+++ + + GYI+G
Sbjct: 122 CDIATYFITQNTGFPADRVISAGCIIDTARLMKLVSEKVDVDPKNVSGYILG 173
>UniRef50_Q97DC6 Cluster: L-lactate dehydrogenase 2; n=1;
Clostridium acetobutylicum|Rep: L-lactate dehydrogenase
2 - Clostridium acetobutylicum
Length = 320
Score = 118 bits (285), Expect = 9e-26
Identities = 59/175 (33%), Positives = 103/175 (58%), Gaps = 4/175 (2%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR--NAKIQ 300
+K+ +VG G VG A S+L+ N+ + + ++D+ +K KGE +D H ++F N K++
Sbjct: 6 NKLVVVGAGMVGSAVLNSVLSLNLLSEVVIIDINDNKAKGEALDASHTTSFAYSPNVKVR 65
Query: 301 SSTDYSITAGSKICVVTAGVRQREGES--RLDLVQRNTDVLKQIIPQLIKYSPDTILVIA 474
+ +Y A ++I V+TAG + + RL L N V I+ + KY+ D I+++
Sbjct: 66 AG-NYEDCADAQIIVITAGPSLKPDDKLDRLVLADTNVKVTDSIMKNICKYTKDAIIIVV 124
Query: 475 SNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+NPVDI TY PK+++IG+GT LD+AR R ++ + + + + HGY++G
Sbjct: 125 TNPVDIATYYCQNNFDYPKNKIIGTGTLLDTARMRKIIGKKYNVDSKNVHGYVLG 179
>UniRef50_UPI000038D9FF Cluster: COG0039: Malate/lactate
dehydrogenases; n=2; Nostoc punctiforme PCC 73102|Rep:
COG0039: Malate/lactate dehydrogenases - Nostoc
punctiforme PCC 73102
Length = 317
Score = 118 bits (284), Expect = 1e-25
Identities = 60/172 (34%), Positives = 99/172 (57%), Gaps = 1/172 (0%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
SKV I+G G VG A +++ + L D K +G++ D++ ++ +I S
Sbjct: 6 SKVGIIGAGNVGADVANALVLLGRCVRVVLFDRTLSKAEGQVWDIEDSIPLLKEMEIIPS 65
Query: 307 TDYSITAGSKICV-VTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
Y A S I + VTAGV+ + G++RLD + N ++++ I +L + +P++I++I SNP
Sbjct: 66 NQYEDLADSDIIIIVTAGVQPKLGQTRLDTLSDNAEIIRSTIKELDRVAPNSIVIIISNP 125
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VD+LT + S ++ + GSGT LD+AR RY L +L +A H Y+IG
Sbjct: 126 VDVLTRIAQATSTRAENLIFGSGTVLDTARLRYQLGKQLNVAKQDIHAYVIG 177
>UniRef50_A7GYI6 Cluster: Lactate/malate dehydrogenase, NAD binding
domain protein; n=2; Campylobacter|Rep: Lactate/malate
dehydrogenase, NAD binding domain protein -
Campylobacter curvus 525.92
Length = 297
Score = 118 bits (284), Expect = 1e-25
Identities = 56/171 (32%), Positives = 99/171 (57%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDL-QHGSAFMRNAKIQSS 306
K++++G G VG + A+++ + V + IALVD+ D + + +D+ Q G F
Sbjct: 2 KISVIGAGNVGASIAYALAMRGVCDEIALVDIFGDVARAKAIDIAQAGCVFCGCLSTAGG 61
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
D+++ S I VVTAG ++EG++R DL+ +N V+KQ + K++P+ I++I +NP+
Sbjct: 62 DDFALIEASDIVVVTAGSPRKEGQTREDLLLKNAQVVKQTAQNIAKFAPNAIVIIVTNPL 121
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D++ + + SG + RVIG LDSAR RY ++ I+ ++G
Sbjct: 122 DVMVWTVLRYSGFDRSRVIGMAGELDSARCRYEIASLKDISAKDVSAKVLG 172
>UniRef50_A1C5Q5 Cluster: L-lactate dehydrogenase; n=4;
Pezizomycotina|Rep: L-lactate dehydrogenase -
Aspergillus clavatus
Length = 312
Score = 118 bits (283), Expect = 2e-25
Identities = 65/172 (37%), Positives = 103/172 (59%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA--KIQS 303
++ IVGVGQVG AAA +++ +V + LVD+ ++ +L S A +I++
Sbjct: 9 RIAIVGVGQVGGAAANALILGSVARELLLVDVKIPLRNAQVQELSDVSNMSGGAETRIRA 68
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
T Y I V+TAG + GE+ + + RN ++++IIP + + PDTIL++ SNP
Sbjct: 69 GT-YEEAGQCDIVVITAGSKYSVGETSVQHMYRNMGIVQKIIPAMRPFRPDTILLVVSNP 127
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VD+LT V ++SGLP +V+GSGT L+S R R L++ G+A S Y++G
Sbjct: 128 VDLLTTVAQQLSGLPPTQVLGSGTLLESVRLRGLVAKTTGVAPDSVDLYVLG 179
>UniRef50_A7I2F1 Cluster: Malate dehydrogenase; n=1; Campylobacter
hominis ATCC BAA-381|Rep: Malate dehydrogenase -
Campylobacter hominis (strain ATCC BAA-381 / LMG 19568 /
NCTC 13146 /CH001A)
Length = 297
Score = 116 bits (280), Expect = 4e-25
Identities = 55/172 (31%), Positives = 95/172 (55%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVT-NNIALVDMMADKLKGEMMDLQH-GSAFMRNAKIQS 303
K++I+G G +G +L ++ + IAL+D+ D K +DL H S + + +I
Sbjct: 2 KISIIGAGNIGSNIVSQLLCKDFEISQIALIDIFGDLAKARALDLSHLASVYNKKTEISG 61
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
S+D ++ S I V+TAG ++ G+SR DL+ N ++ + KY+P+ I+++ +NP
Sbjct: 62 SSDETLLKNSDIVVITAGKTRQAGQSRADLLNDNAKIISSCAKNVAKYAPEAIIILITNP 121
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VD L +V +K SG K ++I LDSAR RY ++ + T ++G
Sbjct: 122 VDTLAFVAYKASGFKKEKIIAMAGELDSARLRYEIAKSENVNVTDIKASVVG 173
>UniRef50_A4A2L6 Cluster: L-lactate dehydrogenase; n=4;
Bacteria|Rep: L-lactate dehydrogenase - Blastopirellula
marina DSM 3645
Length = 313
Score = 116 bits (280), Expect = 4e-25
Identities = 68/173 (39%), Positives = 96/173 (55%), Gaps = 3/173 (1%)
Frame = +1
Query: 130 KVTIVGVGQ-VGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
KV+I+G G VG AAF++ + IAL+D+ AD G +DL HG+ + + I S
Sbjct: 2 KVSIIGGGGLVGSCAAFALQCGGIAREIALLDLNADLAGGHALDLLHGAPSVADQVITSG 61
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIK--YSPDTILVIASN 480
I IC+ TAG+R++ ESRLDL+ RN D+ I+ + D I + SN
Sbjct: 62 GYEHIPDSDVICI-TAGLRRKPDESRLDLINRNVDLFLSILDSVKSAGVKKDAICFVVSN 120
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
PVDILTY+ + LP RVIG GT LD+ RFR L++ + + T I+G
Sbjct: 121 PVDILTYLAAQRLNLPTSRVIGLGTQLDTIRFRALIAQEMKLPPTQVKALILG 173
>UniRef50_Q979N9 Cluster: Malate dehydrogenase; n=4;
Thermoplasmatales|Rep: Malate dehydrogenase -
Thermoplasma volcanium
Length = 325
Score = 116 bits (280), Expect = 4e-25
Identities = 58/176 (32%), Positives = 102/176 (57%), Gaps = 6/176 (3%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAF------MRNA 291
K++++G G VG A + T+ + ++ L D++ +G+ +D+Q G+ +
Sbjct: 5 KISVIGAGNVGATVAQFLATKEL-GDVYLFDVVDGIPEGKALDIQEGAPHWGYDLDVVGF 63
Query: 292 KIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVI 471
S++Y GS + VVTAG+ ++ G SR DL +N +++ + + KYSPD+I+V+
Sbjct: 64 STSDSSNYKNMEGSDVIVVTAGMARKPGMSREDLFDKNVEIIADVSKNIKKYSPDSIIVV 123
Query: 472 ASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
SNP DI+ Y KISG+ R++G G +LDS+RFR L+ L ++ + ++IG
Sbjct: 124 VSNPADIMAYALQKISGVDPQRIMGLGGSLDSSRFRTFLAKELDVSVEDVNAFVIG 179
>UniRef50_Q7UY63 Cluster: L-lactate/malate dehydrogenase; n=2;
Planctomycetaceae|Rep: L-lactate/malate dehydrogenase -
Rhodopirellula baltica
Length = 304
Score = 116 bits (279), Expect = 5e-25
Identities = 65/172 (37%), Positives = 103/172 (59%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSS 306
K+T+VG G+VG A AF++ + + + L++ +K +G+ +DL H +A + N KI SS
Sbjct: 2 KITLVGTGRVGSAIAFALTINPLASELLLLNRSREKAEGDALDLTHAAALVDSNIKI-SS 60
Query: 307 TDYSITAGSKICVVTAGVRQR-EGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
+ + + S + + TA V R ++RL++ N +L+ +P L K SP+ I+V+ SNP
Sbjct: 61 GEIADSKDSDVIIFTASVPFRYPNQTRLEMGIDNMPILRDWMPGLAKASPNAIVVMVSNP 120
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VD L Y T +++G RVIG+GT +DS R+R LLS L I YI+G
Sbjct: 121 VDALAYETIRLTGFDPKRVIGTGTLVDSIRYRALLSTELKIHAQDIRAYILG 172
>UniRef50_Q185V1 Cluster: L-lactate dehydrogenase; n=3;
Clostridium|Rep: L-lactate dehydrogenase - Clostridium
difficile (strain 630)
Length = 322
Score = 116 bits (279), Expect = 5e-25
Identities = 63/176 (35%), Positives = 101/176 (57%), Gaps = 6/176 (3%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSS 306
K++IVG G VG FS++TQ V + + ++D+ K K + +DL +++ I+
Sbjct: 7 KISIVGSGHVGSHCGFSLITQGVCDELFMIDIDESKSKAQALDLADAVSYLPHKVHIEKG 66
Query: 307 TDYSITAGSKICVVTA-----GVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVI 471
T +S S I V++ G +R+ +RLDL++ ++K I+ ++ D I V+
Sbjct: 67 T-FSDCKDSDIVVISVADSSEGPLRRQNTTRLDLLRPTIGMIKSIVKPIVDSGFDGIFVV 125
Query: 472 ASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
SNPVD++T W+ SG PK++VIG+GT LDS R R +LS+ GIA S Y +G
Sbjct: 126 ISNPVDVVTNYIWEKSGFPKNKVIGTGTALDSTRLRRILSEETGIAQQSIQAYSMG 181
>UniRef50_A0RXX8 Cluster: Malate/L-lactate dehydrogenase; n=1;
Cenarchaeum symbiosum|Rep: Malate/L-lactate
dehydrogenase - Cenarchaeum symbiosum
Length = 302
Score = 115 bits (277), Expect = 8e-25
Identities = 56/170 (32%), Positives = 102/170 (60%), Gaps = 1/170 (0%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSST 309
+TI+G G+VG AA + + + I L+D++ +GE MD+ H A + +++ S
Sbjct: 2 ITIIGAGKVGGDAAMFCALRRLDSEILLLDIVEGLPQGEAMDINHMLAEQGIDTEVRGSN 61
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
DYS GS I VV AG ++ G +R+DL++ N ++K ++ ++ +++ D++++ +NP+D
Sbjct: 62 DYSDMEGSDIVVVVAGAGRKPGMTRMDLLKINAGIVKGVVEKVKEHAKDSMIIPVTNPLD 121
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+TY+ +K SG K+RV G G LD +RFR + + G + S ++G
Sbjct: 122 PITYIAYKTSGFEKNRVFGMGGMLDLSRFRQFIHEATGYSRDSIRALVMG 171
>UniRef50_UPI0000DB7267 Cluster: PREDICTED: similar to
Ecdysone-inducible gene L3 CG10160-PA; n=1; Apis
mellifera|Rep: PREDICTED: similar to Ecdysone-inducible
gene L3 CG10160-PA - Apis mellifera
Length = 368
Score = 114 bits (274), Expect = 2e-24
Identities = 56/170 (32%), Positives = 101/170 (59%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
KV+IVGVG++G+A A ++L + + + + L+D A+K E D+QH F+ + ++
Sbjct: 50 KVSIVGVGKIGIACAIAILMRRMASEVCLIDHDANKASAEAEDIQHVGFFLGCPLVTGTS 109
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+ S S + ++ GE++ V+ N V K+IIP + +++ ++L+I + P D
Sbjct: 110 EISTVKESAVVIICTP-ETPPGENQN--VKHNLKVFKKIIPAIARFAAKSVLLIVTRPAD 166
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+++Y+ WK+SG P +RV+G GT +D AR + +S RL +A +S IG
Sbjct: 167 VMSYIAWKLSGFPSNRVLGIGTLIDCARLQDFVSRRLNVARSSVSCMTIG 216
>UniRef50_A5Z9B1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 312
Score = 114 bits (274), Expect = 2e-24
Identities = 58/170 (34%), Positives = 95/170 (55%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ I+G G VG A+++ Q + + I LVD K K MD+ +F ++ I
Sbjct: 6 KIVIIGAGHVGSHCAYALAIQGICDEIVLVDKDRTKAKSHSMDIADSVSFFNSSVIVRCG 65
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
DYS + I V++AGV + G++RLD++ + + ++ I+ L K I++ +NP D
Sbjct: 66 DYSDCKDADIIVISAGVPRLPGQTRLDVLDGSVECVRDIVSNLNKIEIKGIIITITNPAD 125
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
I+ K +GLPK+RV +GT+LD+AR R ++D IA S G+ +G
Sbjct: 126 IIADFVRKATGLPKNRVFSTGTSLDTARMRRTVADLCNIAPQSVIGFAMG 175
>UniRef50_Q03BE6 Cluster: L-lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: L-lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 312
Score = 113 bits (272), Expect = 3e-24
Identities = 55/169 (32%), Positives = 101/169 (59%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTD 312
+ ++G G +G + AF+ LT V ++ ++D+ +++G++ DL + I +++
Sbjct: 7 IILIGDGAIGSSYAFNCLTTGVGQSLGIIDVNEKRVQGDVEDLSDALPYTSQKNIYAAS- 65
Query: 313 YSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDI 492
Y + I V+TAG+ Q+ G++RL L+ N ++K+I ++ + +++ASNPVD+
Sbjct: 66 YEDCKYADIIVITAGIAQKPGQTRLQLLAINAKIMKEITHNIMASGFNGFILVASNPVDV 125
Query: 493 LTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
L + + SGLP+++V+GSGT LDSAR R + R + HGYI+G
Sbjct: 126 LAELVLQESGLPRNQVLGSGTALDSARLRSEIGLRYNVDARIVHGYIMG 174
>UniRef50_O67655 Cluster: Malate dehydrogenase 1; n=3; Bacteria|Rep:
Malate dehydrogenase 1 - Aquifex aeolicus
Length = 335
Score = 113 bits (272), Expect = 3e-24
Identities = 62/183 (33%), Positives = 107/183 (58%), Gaps = 14/183 (7%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDM-------MADKLKGEMMDLQHGSAFMR-N 288
V ++G G VG A +L +N+ N + + D+ + + +KG+ +D++ A M +
Sbjct: 7 VAVIGAGNVGEHVASLILLKNLAN-VKMFDLPRKTEEKVFEPVKGKALDMKQMLAAMDID 65
Query: 289 AKIQSST------DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYS 450
A+++ T Y GS I V+TAG +R G SR DL++ N ++ I ++ +Y+
Sbjct: 66 ARVEGYTVTPEGEGYEPLEGSDIVVITAGFPRRPGMSREDLLEANIRIISVIADRIKRYA 125
Query: 451 PDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGY 630
PD I+++ +NPVD++TYV +K+ PK+RV+G LDSARF+ +S+ L ++ H Y
Sbjct: 126 PDAIVIVVTNPVDVMTYVAYKLLNFPKNRVMGMAGVLDSARFKTFISEELMVSPKDIHAY 185
Query: 631 IIG 639
+IG
Sbjct: 186 VIG 188
>UniRef50_Q3U1V6 Cluster: Ubiquitin-conjugating enzyme E2 variant 3;
n=23; Tetrapoda|Rep: Ubiquitin-conjugating enzyme E2
variant 3 - Mus musculus (Mouse)
Length = 471
Score = 112 bits (270), Expect = 6e-24
Identities = 58/171 (33%), Positives = 99/171 (57%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
+K+T+VG G +G+A ++ + + + + L+D+ +D + MDL ++ S
Sbjct: 183 NKITVVGSGDLGIACTLAISAKGIADKLLLLDL-SDGMSQGTMDLD----IFNLPNVEIS 237
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
D S +A SK+ + TA ES L VQ N D+ + ++P L YS +L++AS PV
Sbjct: 238 KDLSASAHSKVVIFTAN-SLGGSESYLHAVQSNVDMFRALVPALGHYSQHAVLLVASQPV 296
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+I++YVTWK+S P RV+G G NLDS R +Y+++ L + T+ +++G
Sbjct: 297 EIMSYVTWKLSTFPATRVVGIGCNLDSQRLQYIITSVLKVQTSGKEVWVVG 347
>UniRef50_Q07841 Cluster: Malate dehydrogenase; n=7;
Halobacteriaceae|Rep: Malate dehydrogenase - Haloarcula
marismortui (Halobacterium marismortui)
Length = 304
Score = 112 bits (270), Expect = 6e-24
Identities = 59/174 (33%), Positives = 100/174 (57%), Gaps = 3/174 (1%)
Frame = +1
Query: 127 SKVTIVGV-GQVGMAAAFSMLTQNVTNNIALVDM--MADKLKGEMMDLQHGSAFMRNAKI 297
+KV++VG G VG AA +++ +++ + + VD+ D G+ D HG A+ N ++
Sbjct: 2 TKVSVVGAAGTVGAAAGYNIALRDIADEVVFVDIPDKEDDTVGQAADTNHGIAYDSNTRV 61
Query: 298 QSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIAS 477
+ Y TAGS + V+TAG+ ++ G++R+DL N +++ I L +++ D I + S
Sbjct: 62 RQG-GYEDTAGSDVVVITAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHNDDYISLTTS 120
Query: 478 NPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
NPVD+L ++ + +VIG G LDSARFRY+LS+ + G I+G
Sbjct: 121 NPVDLLNRHLYEAGDRSREQVIGFGGRLDSARFRYVLSEEFDAPVQNVEGTILG 174
>UniRef50_Q3J7E7 Cluster: Malate dehydrogenase; n=5;
Gammaproteobacteria|Rep: Malate dehydrogenase -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 311
Score = 112 bits (269), Expect = 8e-24
Identities = 53/171 (30%), Positives = 97/171 (56%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA-FMRNAKIQSS 306
K+TIVG G+VG A A ++ + + L+D +G +D+Q + F +A++ S
Sbjct: 5 KITIVGAGRVGEATAQFLVKNELCRELVLLDAQEGVAQGAALDIQQSAPLFDFDARVTGS 64
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
T+Y + A S + V+TAG ++ G SR D++ N ++ I+ +++++P ++++I +NPV
Sbjct: 65 TNYELIADSDLVVITAGKPRKPGMSRSDVLDSNLPIITDIMNNVMRFAPQSLVMIVTNPV 124
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D+LTY W+ G + RV G LDSAR ++ G++ ++G
Sbjct: 125 DVLTYHAWRHCGWDRARVFGQAGVLDSARMASFIAGETGLSVKDISAMVLG 175
>UniRef50_A7DRG3 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 304
Score = 111 bits (267), Expect = 1e-23
Identities = 54/170 (31%), Positives = 99/170 (58%), Gaps = 1/170 (0%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSST 309
+TI+G G+VG AA + + + I L+D+ +GE MD+ H + + +++ S
Sbjct: 2 ITIIGSGKVGGDAALFSALKRLDDQILLLDVAEGLPQGEAMDINHMLSEQGIDVEVKGSN 61
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
++ GS I VV AG ++ G +R+DL++ N ++K ++ + KY+ D++++ +NP+D
Sbjct: 62 NFEDMKGSNIVVVVAGSGRKPGMTRMDLLKINASIVKSVVENVKKYADDSMIIPVTNPLD 121
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+ Y+T+K+SG + RV G G LD +RFR + + G + S +IG
Sbjct: 122 PMAYITYKVSGFDRSRVFGMGGMLDLSRFRQFIHEATGHSRDSIRALVIG 171
>UniRef50_Q7NHJ3 Cluster: Malate dehydrogenase; n=13; cellular
organisms|Rep: Malate dehydrogenase - Gloeobacter
violaceus
Length = 325
Score = 111 bits (267), Expect = 1e-23
Identities = 57/172 (33%), Positives = 99/172 (57%), Gaps = 1/172 (0%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQS 303
SKV+I+G G VG A A ++ NV + + L+D++ + +G +DL +I
Sbjct: 9 SKVSILGAGNVGSALAQRLIQGNVAD-VVLLDIVEGRPQGITLDLLEACGVEGHTCRITG 67
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
+ DY+ TAGS + VV AG ++ G SR DL+ NT ++ ++ + + +SP+ +V+ +NP
Sbjct: 68 TNDYAQTAGSDVLVVAAGFARQPGMSRDDLLLTNTRIVFEVTQKAVAHSPEATVVVVTNP 127
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+D +++V W+ SGL RV+G LD+ARF ++ LG + ++G
Sbjct: 128 LDAMSHVAWRASGLVPERVMGMAGVLDAARFETFIAWELGFSVRDIRAMVLG 179
>UniRef50_Q9CGG8 Cluster: L-lactate dehydrogenase 3; n=3;
Lactococcus lactis|Rep: L-lactate dehydrogenase 3 -
Lactococcus lactis subsp. lactis (Streptococcus lactis)
Length = 323
Score = 111 bits (266), Expect = 2e-23
Identities = 58/173 (33%), Positives = 100/173 (57%), Gaps = 4/173 (2%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA-KIQSS 306
KV IVG G VG A +++ ++ + IA+++ K +DL H ++ A K +
Sbjct: 7 KVVIVGAGAVGSTYAHNLVVDDLADEIAIINTNKSKASANSLDLLHALPYLNAAPKNIYA 66
Query: 307 TDYSITAGSKICVVTAGVRQR---EGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIAS 477
DYS + + I V++A + RL L++ ++++ I + + D I ++AS
Sbjct: 67 ADYSDVSDADIVVLSANAPSATFGKNPDRLQLLENKVEMIRDITRKTMDAGFDGIFLVAS 126
Query: 478 NPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYII 636
NPVD+L V ++SGLPKHRVIG+GT L+++R R +++++L I S HGY++
Sbjct: 127 NPVDVLAQVVAEVSGLPKHRVIGTGTLLETSRMRQIVAEKLQINPKSIHGYVL 179
>UniRef50_Q8RED8 Cluster: L-lactate dehydrogenase; n=3;
Fusobacterium nucleatum|Rep: L-lactate dehydrogenase -
Fusobacterium nucleatum subsp. nucleatum
Length = 318
Score = 110 bits (265), Expect = 2e-23
Identities = 62/171 (36%), Positives = 98/171 (57%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
KV IVG+G VG A SML Q V + + L+D++ +K K +D +F+ + I
Sbjct: 6 KVGIVGIGHVGSHCALSMLLQGVCDEMVLMDIIPEKAKAHAIDCMDTISFLPHRAI--IR 63
Query: 310 DYSITAGSKICVVTAGVRQ-REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
D I SK+ V+ V + E RL+ ++ + + +K +P ++K + I V +NPV
Sbjct: 64 DGGIQELSKMDVIVISVGSLTKNEQRLEELKGSLEAIKSFVPDVVKAGFNGIFVTITNPV 123
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DI+TY ++SG PK+RVIG+GT LDSAR + +LS+ I + Y++G
Sbjct: 124 DIVTYFVRELSGFPKNRVIGTGTGLDSARLKRILSEVTNIDSQVIQAYMLG 174
>UniRef50_Q87JV1 Cluster: Lactate dehydrogenase; n=4; Vibrio|Rep:
Lactate dehydrogenase - Vibrio parahaemolyticus
Length = 317
Score = 110 bits (264), Expect = 3e-23
Identities = 51/172 (29%), Positives = 101/172 (58%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA--FMRNAKIQS 303
K+ ++G G VG+ +LT + + L+D ++ +GE+ D +H +A F +N +I
Sbjct: 2 KIGVIGAGAVGVGVCNYLLTLGSVSELVLLDQNLERAEGEVFDFRHTAALTFSKNTRIIP 61
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
S DY G+ I V+TAG + ++G++RLD+ + N + +I ++ + +P +L++ SNP
Sbjct: 62 SDDYLDLLGADIVVITAGAQIQQGQTRLDIAEINAKIGVEIARKIERVAPKAVLIVVSNP 121
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DI+ + +G ++VI SG +D+AR ++++R+ + + GY++G
Sbjct: 122 CDIVAHFITTNTGFEPNKVISSGCVIDTARLMSIVANRVDLDPKNIFGYVLG 173
>UniRef50_P47698 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
genitalium
Length = 312
Score = 107 bits (257), Expect = 2e-22
Identities = 56/171 (32%), Positives = 99/171 (57%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ IVG G VG + ++ +T+ + + ++D+ G + DLQ S+ N +
Sbjct: 5 KIAIVGSGAVGTSFLYAAMTRALGSEYMIIDINEKAKVGNVFDLQDASSSCPNFGKVVAG 64
Query: 310 DYSITAGSKICVVTAGVRQREG-ESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
+YS ++AG Q++G E+RL L++ N +++K I ++ K + + +IASNPV
Sbjct: 65 EYSQLKDYDFIFISAGRPQKQGGETRLQLLEGNVEIMKSIAKEIKKSGFNGVTLIASNPV 124
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
DI++Y K++G ++VIGSGT LDSAR RY ++ + +++ Y+IG
Sbjct: 125 DIMSYTYLKVTGFEPNKVIGSGTLLDSARLRYAIATKYQMSSKDVQAYVIG 175
>UniRef50_Q8YJE7 Cluster: Malate dehydrogenase; n=98; Bacteria|Rep:
Malate dehydrogenase - Brucella melitensis
Length = 320
Score = 106 bits (255), Expect = 4e-22
Identities = 53/172 (30%), Positives = 96/172 (55%), Gaps = 1/172 (0%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQS 303
+K+ ++G G +G A + + ++ L D+ +G+ +D+ S +AK
Sbjct: 4 NKIALIGSGMIGGTLAHLAGLKEL-GDVVLFDIAEGTPQGKGLDIAESSPVDGFDAKFTG 62
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
+ DY+ G+ + +VTAGV ++ G SR DL+ N V++Q+ + KY+P+ ++ +NP
Sbjct: 63 ANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITNP 122
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+D + + K SGLP H+V+G LDSARFRY LS+ ++ +++G
Sbjct: 123 LDAMVWALQKFSGLPAHKVVGMAGVLDSARFRYFLSEEFNVSVEDVTAFVLG 174
>UniRef50_Q6KIP9 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
mobile|Rep: L-lactate dehydrogenase - Mycoplasma mobile
Length = 318
Score = 105 bits (252), Expect = 9e-22
Identities = 54/177 (30%), Positives = 98/177 (55%), Gaps = 1/177 (0%)
Frame = +1
Query: 112 VDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLK-GEMMDLQHGSAFMRN 288
+D+ +V +VG G VG++ +S + + + ++D+ DKL G +D + SA +
Sbjct: 1 MDKKIKRVAMVGAGLVGVSVLYSCMNRGLAEQYGIIDIN-DKLSVGHSLDFEDASAANNH 59
Query: 289 AKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILV 468
+YS + V+TAG Q+ GE+RL++V N ++ I + K + +
Sbjct: 60 NFSVGKIEYSDLKDYDVVVITAGRPQKPGETRLEMVADNAKIMSNIAKNIKKSGFKGVSI 119
Query: 469 IASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+ +NPVD++T++ +G K+RVI SGT+LDSAR R+ +S +L + S +++G
Sbjct: 120 VVANPVDVMTFIYQHETGFDKNRVISSGTSLDSARLRFEISKKLKVHPKSVQAFVLG 176
>UniRef50_UPI000023CE12 Cluster: hypothetical protein FG10444.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG10444.1 - Gibberella zeae PH-1
Length = 309
Score = 105 bits (251), Expect = 1e-21
Identities = 51/171 (29%), Positives = 99/171 (57%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
S+V IVGVG+VG A A+++ ++ + + LVD+ ++ DL + ++ S
Sbjct: 5 SRVAIVGVGEVGGAVAYNLTLNSMASELLLVDLDPSARNAQIEDLSDVTYSTNSSTRVRS 64
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
Y A + V+TA + G++ +D RNT +L+ ++ + + DT+L+I ++PV
Sbjct: 65 ATYHEAAQCDLVVITAASKHMLGQTTIDYTSRNTSMLRGVMEAMKPFRADTVLLIVADPV 124
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D+LT + ++SGLP+ +V G+GT LD+ R R +++ R ++ + +++G
Sbjct: 125 DLLTSLAKQMSGLPESQVFGTGTALDTYRLRGMIASRALVSPYTVDAFVVG 175
>UniRef50_A6Q7S2 Cluster: Malate dehydrogenase, NAD-dependent; n=1;
Sulfurovum sp. NBC37-1|Rep: Malate dehydrogenase,
NAD-dependent - Sulfurovum sp. (strain NBC37-1)
Length = 320
Score = 105 bits (251), Expect = 1e-21
Identities = 51/171 (29%), Positives = 95/171 (55%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDL-QHGSAFMRNAKIQSS 306
KVT++G G G AF + +++ L D KG+ +D+ Q +A ++ ++++
Sbjct: 6 KVTVIGTGNFGSTVAFILAMNGSCHHVMLRGRNYDVAKGKALDMSQAANAARQHTIVKAA 65
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
GS + ++TAG + G SR DL+ +N D++K ++ +Y+PD I+++ SNP+
Sbjct: 66 KGPEDMEGSDVVIITAGAPRTPGMSRDDLLFKNADIVKCYSREIKEYAPDAIVIVVSNPL 125
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D++TYV K +G P+ RV+G LD+AR + + ++L ++G
Sbjct: 126 DVMTYVALKETGFPRQRVLGMAGILDAARMAHFIYEKLEYGAGQIRATVMG 176
>UniRef50_A7U552 Cluster: Mitochondrial malate-dehydrogenase; n=2;
Toxoplasma gondii|Rep: Mitochondrial
malate-dehydrogenase - Toxoplasma gondii
Length = 470
Score = 104 bits (249), Expect = 2e-21
Identities = 50/171 (29%), Positives = 95/171 (55%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSS 306
K+ ++G G +G A + + ++ + D++ D +G+ +DL + + + + S
Sbjct: 159 KIGLIGGGNIGATLALLSAVKEL-GDVVMFDVVQDLPQGKCLDLYQLTPISGVDVRFEGS 217
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
DYS+ + + +VTAGV ++ G SR DL+ N ++ Q+ + +Y P+ ++ +NP+
Sbjct: 218 NDYSVLKDADVIIVTAGVPRKPGMSRDDLLAINAKIMGQVGEAIKQYCPNAFVICITNPL 277
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D++ Y+ + GLP H+V G LDSAR R LS+RL ++ H ++G
Sbjct: 278 DVMVYILREKCGLPPHKVCGMAGVLDSARLRTFLSERLNVSVDDIHALVMG 328
>UniRef50_A3ZZ88 Cluster: L-lactate/malate dehydrogenase; n=1;
Blastopirellula marina DSM 3645|Rep: L-lactate/malate
dehydrogenase - Blastopirellula marina DSM 3645
Length = 308
Score = 103 bits (248), Expect = 3e-21
Identities = 54/172 (31%), Positives = 97/172 (56%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA-KIQSS 306
KV+++G+G+VG A A +++ + + + + LV + + E DL H + ++ ++++
Sbjct: 2 KVSLIGLGKVGSAVAHAIVLKGLADELVLVSRRTEMARSEADDLNHAAGLEEHSVEVRAG 61
Query: 307 TDYSITAGSKICVVTAGVRQREGE-SRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
D TAGS + + + + + R + N + L++ IP L SP I V+ +NP
Sbjct: 62 GDVD-TAGSDVILYCDAAQSKTSDVDRYCAARGNLERLRERIPILAAASPQAICVMVTNP 120
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VD++T+ ++SG P+ RV G GT LD+AR R LLS+R + + Y+IG
Sbjct: 121 VDVMTWFALQLSGFPQERVFGVGTLLDTARLRRLLSERWSVHASDVRAYVIG 172
>UniRef50_Q9EVR0 Cluster: L-lactate dehydrogenase; n=1; Selenomonas
ruminantium|Rep: L-lactate dehydrogenase - Selenomonas
ruminantium
Length = 318
Score = 102 bits (245), Expect = 6e-21
Identities = 49/173 (28%), Positives = 96/173 (55%), Gaps = 3/173 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ ++G VG A A + + + L+D+ DK GE D H ++ + + I+
Sbjct: 6 KIVVIGASNVGSAVANKIADFQLATEVVLIDLNEDKAWGEAKDSSHATSCIYSTNIKFHL 65
Query: 310 -DYSITAGSKICVVTAGVRQREGES--RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
DY + I V+TAG R GE+ RL L N ++ ++ +++K + + ++++ +N
Sbjct: 66 GDYEDCKDANIIVITAGPSIRPGETPDRLKLAGTNAKIMSSVMGEIVKRTKEAMIIMITN 125
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
P+D+ TYV P++ ++G+GT L++ RFR +L+D+ + + +GY++G
Sbjct: 126 PLDVATYVVSTQFDYPRNLILGTGTMLETYRFRRILADKYQVDPKNINGYVLG 178
>UniRef50_Q5LXE1 Cluster: Malate dehydrogenase; n=115; cellular
organisms|Rep: Malate dehydrogenase - Silicibacter
pomeroyi
Length = 320
Score = 102 bits (244), Expect = 8e-21
Identities = 50/171 (29%), Positives = 98/171 (57%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDL-QHGSAFMRNAKIQSS 306
K+ ++G GQ+G A + + + ++ L D+ +G+ +D+ + G + +AK++ +
Sbjct: 5 KIALIGAGQIGGTLAHLVALKEL-GDVVLFDIAEGTPEGKALDIAESGPSEGFDAKLKGT 63
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
Y+ AG+ +C+VTAGV ++ G SR DL+ N V+K + + +PD ++ +NP+
Sbjct: 64 QSYADIAGADVCIVTAGVPRKPGMSRDDLLGINLKVMKSVGEGIRDNAPDAFVICITNPL 123
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D + + + SGLP ++V G LDSARFR+ L++ ++ +++G
Sbjct: 124 DAMVWALQQFSGLPANKVCGMAGVLDSARFRHFLAEEFNVSMKDVTAFVLG 174
>UniRef50_UPI00015BB1FC Cluster: malate dehydrogenase (NAD); n=1;
Ignicoccus hospitalis KIN4/I|Rep: malate dehydrogenase
(NAD) - Ignicoccus hospitalis KIN4/I
Length = 311
Score = 101 bits (242), Expect = 1e-20
Identities = 55/171 (32%), Positives = 95/171 (55%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA-FMRNAKIQSS 306
KV ++G G+VG A++M + LVD + KG M D++H +A F R+ ++++
Sbjct: 7 KVAVIGTGRVGATFAYTMAIVPGVARMVLVDAVPGLSKGVMEDIKHAAAVFRRSIQVEAY 66
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
D S + V+TAG ++ SR DL + N +++ I +L +P ++ +NPV
Sbjct: 67 DDVSKVENADAIVITAGKPRKADMSRRDLAKVNAQIIRDIGDKLRDRNPGAFYMVITNPV 126
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D++T + + G K VIG+GT+LD+ RFR +S+ L + GY++G
Sbjct: 127 DVMTMILSDVIG-NKGTVIGTGTSLDTYRFRSAVSELLNEPIAAIDGYVVG 176
>UniRef50_Q92AZ3 Cluster: Lin1775 protein; n=13; Listeria|Rep:
Lin1775 protein - Listeria innocua
Length = 302
Score = 101 bits (242), Expect = 1e-20
Identities = 51/170 (30%), Positives = 94/170 (55%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
KV I+G G VG AFS++TQ + + I ++D + K + E ++L+ ++ R+ ++
Sbjct: 4 KVGIIGAGHVGSDVAFSLVTQGICDEIVIIDKIEAKAESEALELRDMASMTRSYTTITAN 63
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+ + + I V+ G E R++ + + + +I+P+++ I V +NP D
Sbjct: 64 SWEALSDADIIVMAVGPETLLREDRMEELVETSRSVTEIVPKILATGFKGIFVNITNPCD 123
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
++T + KISG RV G+GT+LD+AR R ++ + L I S GY++G
Sbjct: 124 VITMLIQKISGFDHSRVFGTGTSLDTARMRRVVGEALHINPKSIEGYVLG 173
>UniRef50_A0LRV1 Cluster: Lactate/malate dehydrogenase; n=3;
Actinomycetales|Rep: Lactate/malate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 330
Score = 101 bits (242), Expect = 1e-20
Identities = 49/181 (27%), Positives = 96/181 (53%), Gaps = 7/181 (3%)
Frame = +1
Query: 118 ETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAK 294
E KV ++G G G A + ++ + L D++ + +G +D+ K
Sbjct: 10 ERRGKVAVIGAGFYGSTTAQRLAEYDIFETVVLTDIIEGRPEGLALDINQSRPIEGFETK 69
Query: 295 IQSSTD------YSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPD 456
+ T Y + A + I ++TAGV ++ G SR+DL++ N +++ + + KY+P
Sbjct: 70 VIGKTTSPDGAGYEVIADASIVIITAGVPRKPGMSRMDLLETNARIVRGVAENIAKYAPS 129
Query: 457 TILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYII 636
++++ SNP+D +T +T ++G PK+RV+G LD+ARF + +++ LG+ + +
Sbjct: 130 AVVIVVSNPLDEMTALTQLVTGFPKNRVMGQAGMLDTARFSHFVAEELGVPIRAVRTLTL 189
Query: 637 G 639
G
Sbjct: 190 G 190
>UniRef50_A2QJT7 Cluster: Catalytic activity: precursor; n=1;
Aspergillus niger|Rep: Catalytic activity: precursor -
Aspergillus niger
Length = 307
Score = 101 bits (242), Expect = 1e-20
Identities = 50/170 (29%), Positives = 97/170 (57%), Gaps = 1/170 (0%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA-KIQSST 309
+ ++G+G VG + A S++ + + + LVD+ + ++ DL + + KI+++T
Sbjct: 4 IALIGLGSVGASTALSLIHRRIQGTLLLVDIKSSLRDAQVRDLADAALVYGSVTKIEAAT 63
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+ + + + ++TAGV GE+ L + +LK I+ ++ ++P+ I+++ +NPVD
Sbjct: 64 -HQEASQADVVIITAGVNYTPGETTLQHLYHKFSILKSILNEMRPFNPNAIILVVANPVD 122
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
LT + I+GLP+ +VIG GT +DS R + +S LG GY++G
Sbjct: 123 TLTTLAQDIAGLPRKQVIGVGTCIDSLRLQDEVSRFLGTTMEETEGYVVG 172
>UniRef50_O67581 Cluster: Malate dehydrogenase 2; n=1; Aquifex
aeolicus|Rep: Malate dehydrogenase 2 - Aquifex aeolicus
Length = 334
Score = 101 bits (241), Expect = 2e-20
Identities = 61/178 (34%), Positives = 98/178 (55%), Gaps = 8/178 (4%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKL---KGEMMDLQHGSAFMR---NA 291
K++++G G+VG A+ +LT ++ L L K + +DL+ + M N
Sbjct: 15 KISVIGAGKVGENVAY-LLTILGLGDVYLFARYKKGLEPAKAKALDLKQMAVLMDIDINV 73
Query: 292 KIQS--STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTIL 465
K S + GS I V+TAG+ +REG SR DL+ N +LK+ + +Y+ D+I+
Sbjct: 74 KGISYDKEGFEELKGSDIVVITAGIPRREGMSREDLLYENLKILKKFTDAIKEYAKDSII 133
Query: 466 VIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
++ SNPVD LTY T K++G RVIG LDSARF+ + +++GI+ ++G
Sbjct: 134 IVVSNPVDTLTYATIKLTGFEPRRVIGMAGVLDSARFKNFVKEKIGISNADIRTLVLG 191
>UniRef50_Q6YPG1 Cluster: Putative uncharacterized protein
OJA1212_C06.24; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
OJA1212_C06.24 - Oryza sativa subsp. japonica (Rice)
Length = 255
Score = 100 bits (240), Expect = 3e-20
Identities = 61/129 (47%), Positives = 72/129 (55%)
Frame = -3
Query: 593 SDSR*RNRAESKLVPDPMTRCLGSPLIFHVTYVRISTGLLAITNIVSGLYFISCGIICLR 414
S R RN ES+LVP+PMTR G+P FH TYV STGL I++ SG S G I
Sbjct: 47 SARRKRNLEESRLVPEPMTRLAGNPDSFHATYVSTSTGLETISSSASGECSASAGTIFRN 106
Query: 413 TSVFLCTRSRRDSPSRCRTPAVTTQIFEPAVIE*SVLDWILAFLMNADPCCRSIISPFNL 234
++ F C+R RR SP R PAVT EP V SV + NA CCRS ISP +L
Sbjct: 107 SATFRCSRFRRLSPGIWRAPAVTMARSEPRVTARSVSETRRTRGRNAAACCRSSISPRSL 166
Query: 233 SAIMSTRAM 207
S ST A+
Sbjct: 167 SGTASTSAI 175
>UniRef50_A7DSJ4 Cluster: Lactate/malate dehydrogenase; n=1;
Candidatus Nitrosopumilus maritimus SCM1|Rep:
Lactate/malate dehydrogenase - Candidatus Nitrosopumilus
maritimus SCM1
Length = 303
Score = 100 bits (240), Expect = 3e-20
Identities = 56/170 (32%), Positives = 98/170 (57%), Gaps = 2/170 (1%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAK--IQSS 306
++IVG G+VG + AF + N +++ LV+ +K GE +D+ SA N+K I+ +
Sbjct: 5 ISIVGTGRVGASIAF-LCVSNGLDDVLLVNTTKEKAIGESLDV--ASAIPANSKFSIRGT 61
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
DYS GS I ++ A V + R + + ++K I ++ KY P I+++ SNP+
Sbjct: 62 DDYSELIGSDIVIIAASVGIYT-KHRAENIDHQVAMIKNIAKKIKKYCPSAIVLLVSNPL 120
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYII 636
D+LTY K +G + +VIG ++LD++RFRY +S+ L + +S ++
Sbjct: 121 DVLTYFFQKTTGFSRFKVIGIASSLDTSRFRYYISETLSVPQSSVSNALV 170
>UniRef50_Q9PHY2 Cluster: Probable malate dehydrogenase; n=12;
Campylobacter|Rep: Probable malate dehydrogenase -
Campylobacter jejuni
Length = 300
Score = 100 bits (240), Expect = 3e-20
Identities = 49/171 (28%), Positives = 95/171 (55%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSS 306
K+T++G G VG + A++++ + + N I LVD+ D L + ++L A + N + +
Sbjct: 2 KITVIGAGNVGSSVAYALILREIANEIVLVDINEDLLYAKELELTQSIAALNLNIDLLCT 61
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
DY+ T S I + +AG +++G+SR +L+Q NT ++ ++ ++ D + +I +NPV
Sbjct: 62 KDYTHTKNSDIVLFSAGFARKDGQSREELLQLNTSIMLDCAKKIKDFTEDPLFIILTNPV 121
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D L ++ ++I LD+ARF+Y L+ +L + + +IG
Sbjct: 122 DFLLNTLYESGIFSSKKIIAMAGVLDNARFKYELAKKLNVKMSRVDTRLIG 172
>UniRef50_P0C0J4 Cluster: L-lactate dehydrogenase; n=5; Mycoplasma
hyopneumoniae|Rep: L-lactate dehydrogenase - Mycoplasma
hyopneumoniae
Length = 315
Score = 99 bits (238), Expect = 4e-20
Identities = 51/170 (30%), Positives = 91/170 (53%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ ++G G VG + ++ + Q + + ++D+ D G D + SA + S
Sbjct: 5 KIALIGAGNVGNSFLYAAMNQGLASEYGIIDINPDFADGNAFDFEDASASLPFPISVSRY 64
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+Y + V+TAG Q+ GE+RL+LV N ++++I ++ + I +I +NPVD
Sbjct: 65 EYKDLKDADFIVITAGRPQKPGETRLELVADNIRIIREIALKVKESGFSGISIIVANPVD 124
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
I+T SG +VIGSGT LD+AR ++ ++ R ++ S Y++G
Sbjct: 125 IITRAYRDASGFSDQKVIGSGTVLDTARLQFAIAKRAKVSPNSVQAYVMG 174
>UniRef50_Q27743 Cluster: L-lactate dehydrogenase; n=17;
Apicomplexa|Rep: L-lactate dehydrogenase - Plasmodium
falciparum (isolate CDC / Honduras)
Length = 316
Score = 99.5 bits (237), Expect = 6e-20
Identities = 50/177 (28%), Positives = 98/177 (55%), Gaps = 6/177 (3%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQS 303
+K+ +VG G +G A +++ Q ++ L D++ + G+ +D H + N K+
Sbjct: 5 AKIVLVGSGMIGGVMA-TLIVQKNLGDVVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSG 63
Query: 304 STDYSITAGSKICVVTAGVRQREGES-----RLDLVQRNTDVLKQIIPQLIKYSPDTILV 468
S Y AG+ + +VTAG + G+S R DL+ N ++ +I + K P+ ++
Sbjct: 64 SNTYDDLAGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFII 123
Query: 469 IASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+ +NPVD++ + + SG+PK+++IG G LD++R +Y +S +L + + +I+G
Sbjct: 124 VVTNPVDVMVQLLHQHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNAHIVG 180
>UniRef50_O26290 Cluster: Malate dehydrogenase; n=2;
Methanobacteriaceae|Rep: Malate dehydrogenase -
Methanobacterium thermoautotrophicum
Length = 325
Score = 99.1 bits (236), Expect = 8e-20
Identities = 53/174 (30%), Positives = 94/174 (54%), Gaps = 4/174 (2%)
Frame = +1
Query: 130 KVTIVG-VGQVGMAAAFSMLTQNVTNNIALVDMMA--DKLKGEMMDLQHGSAFMR-NAKI 297
KV+I+G G+VG A A + + + L+ ++ GE++D+ A + K+
Sbjct: 2 KVSIIGSTGRVGRATALCLAEEEAVKTLHLISRKESLEQNLGEVLDMSDALAAKGVSVKL 61
Query: 298 QSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIAS 477
++S D GS+I V+TAGV + R DL +N ++ Q+ +++PD+I+++ +
Sbjct: 62 ENSADIENVYGSRIVVITAGVPRTADMDRDDLAFKNGRIVADYARQIARFAPDSIILVVT 121
Query: 478 NPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
NPVD++TYV + SG RV G G +LDS R + ++ + + H +IG
Sbjct: 122 NPVDVMTYVALRYSGFHPSRVFGLGNHLDSLRLKNYMARHFNVHVSEVHTRVIG 175
>UniRef50_Q4A0K7 Cluster: Lactate dehydrogenase; n=1; Staphylococcus
saprophyticus subsp. saprophyticus ATCC 15305|Rep:
Lactate dehydrogenase - Staphylococcus saprophyticus
subsp. saprophyticus (strain ATCC 15305 /DSM 20229)
Length = 310
Score = 97.9 bits (233), Expect = 2e-19
Identities = 51/173 (29%), Positives = 92/173 (53%), Gaps = 2/173 (1%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA--KIQ 300
SK+ I+G+G+VG + N+ + I L+D AD GE +D H + A KI+
Sbjct: 2 SKLGIIGLGKVGTQVLTDVQQLNLFSEIILIDDRADVASGEALDHIHSQGLINTAHIKIR 61
Query: 301 SSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
S +T I + + + R L Q N D++K I+ Q+ + + + ++++ SN
Sbjct: 62 SGVYQDLTDADFIVIAASEATDKNNGDRTLLAQGNHDIIKGIMSQIAEVTQEAVVILISN 121
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
PVD + Y +I P H++IG+GT L+++RF+ +++D I + ++IG
Sbjct: 122 PVDSMVYFANQID-YPAHKIIGTGTALETSRFKTIIADHYQIDPNNVEAFVIG 173
>UniRef50_Q8I8U4 Cluster: Lactate dehydrogenase; n=3;
Eimeriorina|Rep: Lactate dehydrogenase - Eimeria tenella
Length = 331
Score = 97.9 bits (233), Expect = 2e-19
Identities = 55/186 (29%), Positives = 100/186 (53%), Gaps = 6/186 (3%)
Frame = +1
Query: 100 VHEKVDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAF 279
V EKV K+ +VG G +G F + + ++ L D++ + G+ +DL H +A
Sbjct: 3 VFEKVRRP--KIALVGSGMIGGTMGF-LCSLRELGDVVLFDVVPNMPAGKALDLCHTAAV 59
Query: 280 MRNA-KIQSSTDYSITAGSKICVVTAGVRQREGES-----RLDLVQRNTDVLKQIIPQLI 441
N ++Q + Y+ G+ + ++TAG+ + G+S R DL+ N +L+++ +
Sbjct: 60 ADNGVRVQGANSYASLEGADVVIITAGITKAAGKSDQEWSRKDLLPVNVKILREVGAAIK 119
Query: 442 KYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSC 621
++ P ++ +NP+D++ + +GLP RV G LDSARFR LL+DRLG++
Sbjct: 120 QFCPHAFVINITNPLDVMVAALREAAGLPAARVCGMAGVLDSARFRRLLADRLGVSPRDV 179
Query: 622 HGYIIG 639
++G
Sbjct: 180 QAMVLG 185
>UniRef50_A7I5J9 Cluster: L-lactate dehydrogenase precursor; n=1;
Candidatus Methanoregula boonei 6A8|Rep: L-lactate
dehydrogenase precursor - Methanoregula boonei (strain
6A8)
Length = 332
Score = 96.7 bits (230), Expect = 4e-19
Identities = 60/175 (34%), Positives = 92/175 (52%), Gaps = 4/175 (2%)
Frame = +1
Query: 127 SKVTIVGV-GQVGMAAAFSMLTQNVTNNIALVDMMADK--LKGEMMDLQHGSAFM-RNAK 294
SKVTI+G G VG AA+++ + I L + LKG D A N +
Sbjct: 2 SKVTIIGATGNVGTFAAYAVSVDPHVHEILLYGREGREAFLKGLAQDFADSFAARGTNIR 61
Query: 295 IQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIA 474
+ +T AGS I V+TAG + G++RLDL N ++ + + +PDT +++
Sbjct: 62 VTWTTSLKDVAGSDIVVITAGTPRGPGQNRLDLALGNARIIAPMARTIGTIAPDTKIIMV 121
Query: 475 SNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+NPVD++T V K SGL ++V G GT+LDS R + L++ + + H IIG
Sbjct: 122 TNPVDVMTCVALKYSGLKPNQVFGLGTHLDSMRLKSLIASYFKVHVSEVHTRIIG 176
>UniRef50_Q03ZZ4 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=3;
Lactobacillales|Rep: Enzyme with possible activities of
L-2- hydroxyisocaproate/malate/lactate dehydrogenase -
Leuconostoc mesenteroides subsp. mesenteroides (strain
ATCC 8293 /NCDO 523)
Length = 304
Score = 96.3 bits (229), Expect = 5e-19
Identities = 50/172 (29%), Positives = 93/172 (54%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSS 306
K+ +VG+G VG+ A ++ Q + + I LVD +KL E +D + ++ + + ++ +
Sbjct: 3 KIGVVGIGHVGVTVAHIIIAQGLADEIVLVDKNPEKLASEELDFRDAASLLDHHVEVHAG 62
Query: 307 TDYSITAGSKICVVTAGVRQ-REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
T +T + + + G R ++ NT ++Q+ L + + +L++ SNP
Sbjct: 63 TVTDLTDAEVVISALGHIELIKPGGDRFTELKANTPEVQQVGSDLKQAGFNGVLIVISNP 122
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VD++T + K +GLP ++V G+GT LD+AR + L D L I GY++G
Sbjct: 123 VDVITGIYQKATGLPANQVFGTGTYLDTARLKRALGDTLAIDPRGISGYMLG 174
>UniRef50_Q5CYZ2 Cluster: Lactate dehydrogenase, adjacent gene
encodes predicted malate dehydrogenase; n=8;
Cryptosporidium|Rep: Lactate dehydrogenase, adjacent
gene encodes predicted malate dehydrogenase -
Cryptosporidium parvum Iowa II
Length = 337
Score = 95.9 bits (228), Expect = 7e-19
Identities = 47/171 (27%), Positives = 92/171 (53%), Gaps = 1/171 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA-FMRNAKIQSS 306
K+ ++G GQ+G A+ + N+ + + L D+ +G+ +D+ H F +K+ +
Sbjct: 22 KIAVIGSGQIGGNIAYIVGKDNLAD-VVLFDIAEGIPQGKALDITHSMVMFGSTSKVIGT 80
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
DY+ +GS + ++TA + R + R +L+ N +L + + KY P+ ++ +NP+
Sbjct: 81 NDYADISGSDVVIITASIPGRPKDDRSELLFGNARILDSVAEGVKKYCPNAFVICITNPL 140
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D++ K+SGLP ++V G LDS+RFR ++ G+ + +IG
Sbjct: 141 DVMVSHFQKVSGLPHNKVCGMAGVLDSSRFRTFIAQHFGVNASDVSANVIG 191
>UniRef50_A2SSY4 Cluster: L-lactate dehydrogenase; n=3;
Methanomicrobiales|Rep: L-lactate dehydrogenase -
Methanocorpusculum labreanum (strain ATCC 43576 / DSM
4855 / Z)
Length = 319
Score = 95.9 bits (228), Expect = 7e-19
Identities = 61/177 (34%), Positives = 94/177 (53%), Gaps = 6/177 (3%)
Frame = +1
Query: 127 SKVTIVGV-GQVGMAAAFSMLTQNVTNNIALV-----DMMADKLKGEMMDLQHGSAFMRN 288
+KVTI+G GQVG A ++ + L + D L +MMD +A N
Sbjct: 2 AKVTIIGATGQVGSYVAHAVSQFPHVQEMCLYGRPGNEQYLDGLAHDMMD--SFAARGTN 59
Query: 289 AKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILV 468
++ T GS I V+T+GV ++ ++RLDL N ++K Q+ + +P+ IL+
Sbjct: 60 TRVTFGTTPKELRGSDIIVLTSGVPRKATQTRLDLALENARIVKVFAEQVGRMAPEAILL 119
Query: 469 IASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+ +NPVDI+T V K SG+ HRV G GT+LDS R + L++ + + H IIG
Sbjct: 120 VVTNPVDIMTTVALKYSGMMPHRVFGLGTHLDSMRLKACLAEFFNVHVSEIHTRIIG 176
>UniRef50_A2SNY0 Cluster: Malate/lactate dehydrogenases-like
protein; n=1; Methylibium petroleiphilum PM1|Rep:
Malate/lactate dehydrogenases-like protein - Methylibium
petroleiphilum (strain PM1)
Length = 432
Score = 94.7 bits (225), Expect = 2e-18
Identities = 48/150 (32%), Positives = 85/150 (56%), Gaps = 1/150 (0%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSS 306
K +VG G VG A + ++ + +ALVD++ G +D+ HG+ + ++ S
Sbjct: 125 KAGVVGAGHVGAMTALRLAESDLFSEVALVDVVPGLAAGLALDMWHGAGLYGFSTRLSGS 184
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
D AG++ V+TAG ++ G SR DL N +++ + + ++P++ LVI SNP+
Sbjct: 185 DDLVALAGAEYIVITAGKPRQPGMSRTDLTVVNAEIMTSVCRGIRTHAPNSTLVIVSNPL 244
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARF 576
+ +T++ + +G P+ RV+G LDSARF
Sbjct: 245 EEMTHLAAQQTGFPEERVLGMAGVLDSARF 274
>UniRef50_Q7M9A7 Cluster: Malate dehydrogenase; n=4;
Epsilonproteobacteria|Rep: Malate dehydrogenase -
Wolinella succinogenes
Length = 314
Score = 93.9 bits (223), Expect = 3e-18
Identities = 51/168 (30%), Positives = 88/168 (52%), Gaps = 1/168 (0%)
Frame = +1
Query: 139 IVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHG-SAFMRNAKIQSSTDY 315
I+G G VG AF + TQ + I + D+ D +G +D+ H SA + ++ + +
Sbjct: 3 IIGAGHVGSTVAFILATQGICQEIIIKDLNLDTARGIALDMGHAASATKTHTIVRVANEP 62
Query: 316 SITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDIL 495
S G + V AG ++ G SR DL+ N V++ ++ ++ Y +++LV+ SNP+D +
Sbjct: 63 SDLRGCDVVVFCAGSPRQPGMSRDDLLLANAKVIRTVLSEVKPYIQESVLVMVSNPLDAM 122
Query: 496 TYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
Y K SGL +V+G LDSAR + ++LG + ++G
Sbjct: 123 VYTAIKESGLSPLQVLGMAGILDSARMASFIFEKLGYGSDQIVASVMG 170
>UniRef50_A2UB98 Cluster: Lactate/malate dehydrogenase precursor;
n=2; Bacteria|Rep: Lactate/malate dehydrogenase
precursor - Bacillus coagulans 36D1
Length = 327
Score = 93.1 bits (221), Expect = 5e-18
Identities = 51/178 (28%), Positives = 94/178 (52%), Gaps = 7/178 (3%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA--FMRNAKIQ 300
+K+ + GVG VG + + + + IA++D GE +D +H +A +M N ++
Sbjct: 4 TKLVVAGVGHVGSYVLANAMKLGLFSEIAVLDKKKGVAFGEALDWRHATALTYMPNTSVK 63
Query: 301 SSTDYSITAGSKICVVTAGV-----RQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTIL 465
+ DYS A + + + AG + E R L + N V+++++ + KY+ + ++
Sbjct: 64 AG-DYSECADADVIICAAGPSVLPSEKDEMPDRAGLARTNAAVVREVMAGITKYTKEAVI 122
Query: 466 VIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+ +NP+D + Y+ G K R+ G+GT LDSAR R L+++ I S GY++G
Sbjct: 123 IFITNPLDTIVYIAENEFGYSKGRIFGTGTMLDSARLRQLVAENYSIDPKSVTGYMMG 180
>UniRef50_Q6JH30 Cluster: Lactate dehydrogenase; n=3; Plasmodium
(Plasmodium)|Rep: Lactate dehydrogenase - Plasmodium
vivax
Length = 299
Score = 93.1 bits (221), Expect = 5e-18
Identities = 46/173 (26%), Positives = 94/173 (54%), Gaps = 6/173 (3%)
Frame = +1
Query: 139 IVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSSTDY 315
+VG G +G A +++ Q ++ + D++ + +G+ +D H + N K+ S Y
Sbjct: 2 LVGSGMIGGVMA-TLIVQKNLGDVVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNSY 60
Query: 316 SITAGSKICVVTAGVRQREGES-----RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
G+ + +VTAG + G+S R DL+ N ++ +I + P+ +++ +N
Sbjct: 61 DDLKGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVVTN 120
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
PVD++ + ++ SG+PK+++IG G LD++R +Y +S +L + + I+G
Sbjct: 121 PVDVMVQLLFEHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNALIVG 173
>UniRef50_Q1FMY2 Cluster: L-lactate dehydrogenase; n=1; Clostridium
phytofermentans ISDg|Rep: L-lactate dehydrogenase -
Clostridium phytofermentans ISDg
Length = 319
Score = 91.5 bits (217), Expect = 2e-17
Identities = 45/172 (26%), Positives = 90/172 (52%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
KV I+G G VG A +++ Q + I +D+ +K K + +D+ + ++ + S
Sbjct: 6 KVIIIGAGHVGSHAGYALAEQGLAEEIIFIDIDREKAKAQALDIYDATVYLPHRVKVKSG 65
Query: 310 DYSITAGSKICVVTAGVR--QREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
DYS A + + V+ G + +GE+R+ + ++K++ + D ++V SNP
Sbjct: 66 DYSDAADADLMVIAVGTNPDKNKGETRMSTLTNTALIIKEVAWHIKNSGFDGMIVSISNP 125
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D++T+ + +++I + T LDSAR R ++D + I S +G+++G
Sbjct: 126 ADVITHYLQHLLQYSSNKIISTSTVLDSARLRRAIADAVEIDQKSIYGFVLG 177
>UniRef50_Q6VVP7 Cluster: Malate dehydrogenase; n=6; Plasmodium|Rep:
Malate dehydrogenase - Plasmodium falciparum
Length = 313
Score = 91.5 bits (217), Expect = 2e-17
Identities = 48/172 (27%), Positives = 93/172 (54%), Gaps = 1/172 (0%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQS 303
+K+ ++G GQ+G L +N+ ++ L D++ +G+ +DL+H S + N I
Sbjct: 2 TKIALIGSGQIGAIVGELCLLENL-GDLILYDVVPGIPQGKALDLKHFSTILGVNRNILG 60
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
+ + I V+TAGV+++EG +R DL+ N ++K + + + ++ SNP
Sbjct: 61 TNQIEDIKDADIIVITAGVQRKEGMTREDLIGVNGKIMKSVAESVKLHCSKAFVICVSNP 120
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+DI+ V K S LP ++ G LD++R+ L++D+L ++ + I+G
Sbjct: 121 LDIMVNVFHKFSNLPHEKICGMAGILDTSRYCSLIADKLKVSAEDVNAVILG 172
>UniRef50_Q04GC4 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=2;
Oenococcus oeni|Rep: Enzyme with possible activities of
L-2- hydroxyisocaproate/malate/lactate dehydrogenase -
Oenococcus oeni (strain BAA-331 / PSU-1)
Length = 304
Score = 88.2 bits (209), Expect = 1e-16
Identities = 53/172 (30%), Positives = 90/172 (52%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ I+G+G VG + ++ + + + I L+D+ LK E +D +F+ + +
Sbjct: 3 KIGIIGMGHVGSTLSHIVIDRGMVDEIVLLDINQKHLKAEALDFWDAQSFLPHHTKIIAG 62
Query: 310 DYSITAGSKICVVTAGVRQREGES--RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
DY A + + V T G ES R +Q N ++ + QL K D + + +NP
Sbjct: 63 DYKDLADANLIVSTFGNVNLTVESGDRFAELQFNVKQIRSMAEQLKKVHFDGVFLTITNP 122
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VD++T V + LPK++VIG+GT LDS+R + + +R I S G++IG
Sbjct: 123 VDVITAVYQRELALPKNQVIGTGTFLDSSRLKKEIGERFKIDPRSVSGFVIG 174
>UniRef50_A4E9T4 Cluster: Putative uncharacterized protein; n=1;
Collinsella aerofaciens ATCC 25986|Rep: Putative
uncharacterized protein - Collinsella aerofaciens ATCC
25986
Length = 325
Score = 87.4 bits (207), Expect = 3e-16
Identities = 54/172 (31%), Positives = 86/172 (50%), Gaps = 2/172 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSS 306
K+ +VG G VG A S+L Q + + + L D+ K+ E+ DL+ +F+ N KI +
Sbjct: 6 KIGVVGQGHVGAHVANSLLMQGIADELYLCDINEAKVTSEVQDLRDSLSFVPYNTKIVNC 65
Query: 307 TD-YSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
D Y A + V AG +R + TD + +++ D I V SNP
Sbjct: 66 YDHYEELACCDVIVNAAGKVALAAGNRDGELFFTTDAARSFAKRIVDAGFDGIFVSISNP 125
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D++ W ++G ++IGSG LDSAR R +S ++G++ S Y+IG
Sbjct: 126 CDVVCTELWHLTGYDPKKIIGSGCGLDSARLRTEISKKVGVSPKSVDAYMIG 177
>UniRef50_Q38YI2 Cluster: Putative malate dehydrogenase; n=1;
Lactobacillus sakei subsp. sakei 23K|Rep: Putative
malate dehydrogenase - Lactobacillus sakei subsp. sakei
(strain 23K)
Length = 301
Score = 86.6 bits (205), Expect = 4e-16
Identities = 48/173 (27%), Positives = 86/173 (49%), Gaps = 2/173 (1%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
+KV I+G+G VG A++++++ + + + L D + E DL+ G ++
Sbjct: 2 NKVAIIGIGHVGSTVAYTLVSRRICSELVLFDQKPKLAEAERNDLEAGQVDHTGFVKITA 61
Query: 307 TDYSITAGSKICVVTAGVRQ--REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
D S A + + +AG + R D + + Q P+L + IL+ +N
Sbjct: 62 NDESQLATCDLVIFSAGDISILEHSDDRFDELTYTKTAVAQWAPKLKAANFKGILLNITN 121
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
P D++T ++G PK RV+G+GT LD+AR + + L +A S GY++G
Sbjct: 122 PCDVITQYLQALTGFPKERVLGTGTTLDTARMQVAVGHYLNVAPNSVQGYVLG 174
>UniRef50_Q6LZI3 Cluster: Malate dehydrogenase; n=5;
Methanococcus|Rep: Malate dehydrogenase - Methanococcus
maripaludis
Length = 314
Score = 86.2 bits (204), Expect = 6e-16
Identities = 55/175 (31%), Positives = 91/175 (52%), Gaps = 6/175 (3%)
Frame = +1
Query: 133 VTIVGV-GQVGMAAAFSMLTQNVTNNIALVDMMA--DKLKGEMMDLQHGSAFM---RNAK 294
V+I+G G++G + + ++ NI L+ + +KLKG MDL A +
Sbjct: 3 VSIIGASGKIGSVLSLLLAKESHIKNINLIARSSSINKLKGLKMDLYDAMAAAGQDTDID 62
Query: 295 IQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIA 474
I D S TA S I ++TAG+ + SR+DL++ N ++K + + + DT + +
Sbjct: 63 ICCDDDLSCTANSDITIITAGMARTGEMSRIDLMKGNAKIVKNYVKNIANFG-DTKIFMI 121
Query: 475 SNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
SNPVD++TY SG K++V G GT+LDS RF+ ++ + I+G
Sbjct: 122 SNPVDLMTYKALIESGYEKNQVFGLGTHLDSMRFKVAVAKHFEVHLDDVRTRIVG 176
>UniRef50_Q0P989 Cluster: L-lactate dehydrogenase; n=10;
Campylobacter|Rep: L-lactate dehydrogenase -
Campylobacter jejuni
Length = 308
Score = 85.4 bits (202), Expect = 1e-15
Identities = 58/173 (33%), Positives = 89/173 (51%), Gaps = 2/173 (1%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAF-MRNAKIQS 303
+K+ IVG+G VG A+A+S++ Q + + + L D+ D DL+ SA KI
Sbjct: 2 AKIGIVGLGYVGAASAYSIVIQGICSELYLYDIKQDLALAHARDLEDMSAIHFSYTKIFH 61
Query: 304 STDYSITAGSKICVVTAGVRQ-REGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
+ A I ++ +E SRL ++ N LK I+ L + ++A+N
Sbjct: 62 VPNLENLASCDIIILAFRKESLKELPSRLVELKNNILELKDIVLTLKNANFKGKYIVATN 121
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
P D +TY T +S LPK+ V GSGTNLDS+R + LL+ L I + +IG
Sbjct: 122 PNDTITYYTQVLSQLPKNHVFGSGTNLDSSRLKKLLAKDLNINSKDIFACMIG 174
>UniRef50_Q7VFV4 Cluster: Malate dehydrogenase; n=1; Helicobacter
hepaticus|Rep: Malate dehydrogenase - Helicobacter
hepaticus
Length = 315
Score = 84.2 bits (199), Expect = 2e-15
Identities = 51/174 (29%), Positives = 85/174 (48%), Gaps = 2/174 (1%)
Frame = +1
Query: 124 WSKVTIVG-VGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSA-FMRNAKI 297
+ K+ I+G G VG AF +++ I L + KG +D+ +A F I
Sbjct: 2 FEKIAIIGGSGNVGSHIAFLGAMRHIAKEILLFSNDIPRCKGVGLDISQAAAIFDIPILI 61
Query: 298 QSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIAS 477
+ Y A S++ ++TAG + +R DL+ +N ++++I + + +P ++L++ S
Sbjct: 62 KGCNSYEEIAESEVVIITAGFPRTPNMTRNDLLLKNASIIQEISSNVARIAPQSLLIVVS 121
Query: 478 NPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
NP+D + V + S K RVIG LDSAR Y LG Y+IG
Sbjct: 122 NPLDAMCLVAKQWSKFEKERVIGMAGILDSARLTYESKVMLGDFNKHIQSYVIG 175
>UniRef50_Q5M0L6 Cluster: L-2-hydroxyisocaproate dehydrogenase; n=3;
Streptococcus thermophilus|Rep: L-2-hydroxyisocaproate
dehydrogenase - Streptococcus thermophilus (strain CNRZ
1066)
Length = 316
Score = 83.8 bits (198), Expect = 3e-15
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 3/173 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ I+G+G VG A A + Q + ++ +D+ K++ + D + A + N
Sbjct: 4 KIGIIGMGNVGAAVAHGAIAQGLADSYVFIDINERKVEADAQDFKDAMANLANYANIVVN 63
Query: 310 DYSITAGSKICVVTAG---VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
DY + + + G ++ GE R + + Q+ +L + IL++ SN
Sbjct: 64 DYEALKDADVIISALGNIQLQHNAGEDRFAEFPFTREAVYQVAQELKQLDFKGILLVISN 123
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
PVD +T + + +G PK RVIG+GT LD+AR + + + L + S GY +G
Sbjct: 124 PVDAVTALYQEFTGWPKERVIGTGTLLDTARMKTAVGEVLEVNPKSVSGYNLG 176
>UniRef50_Q6A6E3 Cluster: L-lactate dehydrogenase; n=1;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 321
Score = 83.0 bits (196), Expect = 5e-15
Identities = 49/178 (27%), Positives = 89/178 (50%), Gaps = 8/178 (4%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAF--MRNAKIQS 303
K+ I+GVG+VG A + + I ++D+ G+ +D H +A + N + +
Sbjct: 7 KLGIIGVGRVGDAVLSDAMMSGLFGEICVIDVNEKLAAGQALDQHHATALPNVTNVAVYA 66
Query: 304 STDYSITAGSKICVVTAGVR------QREGESRLDLVQRNTDVLKQIIPQLIKYSPDTIL 465
DY + + + ++TAG G +R +L N +++ + Q+ + D +
Sbjct: 67 G-DYDDLSNADVIIMTAGPSIDASNGPATGAARRELAATNGKIIRSTMTQITSRNHDAAI 125
Query: 466 VIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+I SNP+D L ++ P+ V+G+GT LDSAR +++D LG+ GY+IG
Sbjct: 126 IICSNPLDALVHIASTEFDHPQGLVLGTGTILDSARMCRVVADHLGVDPDYVRGYMIG 183
>UniRef50_P14295 Cluster: L-2-hydroxyisocaproate dehydrogenase;
n=15; Lactobacillales|Rep: L-2-hydroxyisocaproate
dehydrogenase - Lactobacillus confusus
Length = 310
Score = 82.6 bits (195), Expect = 7e-15
Identities = 46/174 (26%), Positives = 90/174 (51%), Gaps = 4/174 (2%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ I+G+G VG A A ++ Q V ++ +D K+K + +D Q A +
Sbjct: 4 KIGIIGLGNVGAAVAHGLIAQGVADDYVFIDANEAKVKADQIDFQDAMANLEAHGNIVIN 63
Query: 310 DYSITAGSKICVVTAGVRQREGES----RLDLVQRNTDVLKQIIPQLIKYSPDTILVIAS 477
D++ A + + + T G + + ++ R ++ + +++ + L + +LV+ S
Sbjct: 64 DWAALADADVVISTLGNIKLQQDNPTGDRFAELKFTSSMVQSVGTNLKESGFHGVLVVIS 123
Query: 478 NPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
NPVD++T + ++G P H+VIG+GT LD+AR + + + + S GY +G
Sbjct: 124 NPVDVITALFQHVTGFPAHKVIGTGTLLDTARMQRAVGEAFDLDPRSVSGYNLG 177
>UniRef50_Q88ZG9 Cluster: L-2-hydroxyisocaproate dehydrogenase; n=2;
Lactobacillus plantarum|Rep: L-2-hydroxyisocaproate
dehydrogenase - Lactobacillus plantarum
Length = 319
Score = 80.6 bits (190), Expect = 3e-14
Identities = 44/173 (25%), Positives = 86/173 (49%), Gaps = 3/173 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K I+GVG VG A++++ + + + + L+D A K + E +DLQ A + + I
Sbjct: 3 KYAIIGVGHVGATIAYTLVCKGIADELVLIDTNAAKARAEQLDLQDAQARLDSRTIIKIN 62
Query: 310 DYSITAGSKICVVTAG---VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
DY + I VT+G +R + +++ I P++ + +++ N
Sbjct: 63 DYHELDDTDILFVTSGNIHALDHASGNRWAEFEYTKQIVQDIAPKVKATKFNGVVIDTMN 122
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
P D +T+ + +GL + +V G+GT LD+AR + ++++ + GY+ G
Sbjct: 123 PCDAITHYFQRATGLSRQQVFGTGTFLDTARMQKVVAEAFDCDPKNISGYVYG 175
>UniRef50_Q8IE66 Cluster: Oxidoreductase, putative; n=6;
Plasmodium|Rep: Oxidoreductase, putative - Plasmodium
falciparum (isolate 3D7)
Length = 334
Score = 80.6 bits (190), Expect = 3e-14
Identities = 49/177 (27%), Positives = 90/177 (50%), Gaps = 7/177 (3%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA-KIQSS 306
K++++G G +G A A + +N+ ++ L D D KG +D+ H R+ I +
Sbjct: 8 KISVLGAGDIGCALAHMICEKNL-GDVVLHDFRKDLPKGRALDILHTRPLNRSRINILGT 66
Query: 307 TDYSITAGSKICVVTAGVRQRE----GESRLD--LVQRNTDVLKQIIPQLIKYSPDTILV 468
+ + S + VVT V +RE E L+ + N +LK++ L K+ P +V
Sbjct: 67 NEITDIKDSLVVVVTIEVSEREFAEFDEEDLEKQVYTSNVKLLKEVAKSLKKHCPQAFVV 126
Query: 469 IASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+ ++PVD + V + + +P H++ G L SAR R+ L+++L + G++IG
Sbjct: 127 VTTSPVDCMAKVLQEHANIPPHKICGMAGVLHSARLRHNLAEKLRVNPGDVQGFVIG 183
>UniRef50_O52354 Cluster: L-lactate dehydrogenase; n=1; Mycoplasma
gallisepticum|Rep: L-lactate dehydrogenase - Mycoplasma
gallisepticum
Length = 323
Score = 80.2 bits (189), Expect = 4e-14
Identities = 47/177 (26%), Positives = 86/177 (48%), Gaps = 7/177 (3%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAKIQSS 306
K+ ++G G VG +L Q V + LVD + G + DL+ + N +
Sbjct: 3 KIAVIGCGFVGSTYILDLLQQGVQADYLLVDKNTNLADGHVRDLRDSKSLKSHNGSTFNV 62
Query: 307 TDYSITAGSKICVVTAG---VRQREGE---SRLDLVQRNTDVLKQIIPQLIKYSPDTILV 468
Y + + +TA V +GE RL L+ N +L +I +L + + +
Sbjct: 63 GTYDDLKDADVVAITASIPTVPTADGEVFTDRLQLMTANVKILNEIALELKRVGFKGLSI 122
Query: 469 IASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
I +NP D++ V K++G H++I +G L++ R R ++S+ LG+ + S G+++G
Sbjct: 123 IPTNPCDVMAGVYQKVTGFDPHKIISTGCQLETMRTRKMISEALGVNSDSVEGFVVG 179
>UniRef50_Q2FPC3 Cluster: Lactate/malate dehydrogenase; n=2;
Methanomicrobiales|Rep: Lactate/malate dehydrogenase -
Methanospirillum hungatei (strain JF-1 / DSM 864)
Length = 290
Score = 78.2 bits (184), Expect = 2e-13
Identities = 48/157 (30%), Positives = 78/157 (49%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
+ + + G G++G A ++ + N++ L D L+ + +D++H MR S
Sbjct: 2 TSLAVFGTGRIGGGVAARAVSSGLINHLVLYDCNQALLEAQRLDIEH----MRCPVTTSI 57
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
I A I R + ++R L+ N V ++ + Y I+++ +NP
Sbjct: 58 RPEDIVACDIILYAAGLPRNQNIKTRAALLDCNVPVASELATLIPDYKG--IIIVVTNPA 115
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDR 597
DILTY WK G+ K+R+IG G LDSARF+Y LS R
Sbjct: 116 DILTYYLWKSLGILKNRIIGFGGQLDSARFQYELSLR 152
>UniRef50_Q034P5 Cluster: Enzyme with possible activities of L-2-
hydroxyisocaproate/malate/lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: Enzyme with possible
activities of L-2- hydroxyisocaproate/malate/lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 301
Score = 77.4 bits (182), Expect = 3e-13
Identities = 43/170 (25%), Positives = 82/170 (48%), Gaps = 1/170 (0%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTD 312
+ I+G+G VG+ AF+++++ V + + L+D A+ +GE DL+ + D
Sbjct: 5 IGIIGIGHVGVTTAFNLVSKGVADKLVLIDKKAELAEGESFDLKDALGGLPTYTDIVVND 64
Query: 313 YSITAGSKICVVTAG-VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
Y + + + G + R+ + + L + P+L +L+ +NP D
Sbjct: 65 YDALKDADVVISAVGNIGAISNGDRIGETKTSKVALDDVAPKLKASGFHGVLLDITNPCD 124
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+T + LPK ++IG+GT+LD+ R R ++D L + GY +G
Sbjct: 125 AVTSYWQYLLDLPKSQIIGTGTSLDTYRMRRAVADTLHVNVADVRGYNMG 174
>UniRef50_A3CTN0 Cluster: Lactate/malate dehydrogenase; n=1;
Methanoculleus marisnigri JR1|Rep: Lactate/malate
dehydrogenase - Methanoculleus marisnigri (strain ATCC
35101 / DSM 1498 / JR1)
Length = 288
Score = 77.0 bits (181), Expect = 4e-13
Identities = 48/157 (30%), Positives = 83/157 (52%), Gaps = 1/157 (0%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
+ + I+GVG+VG AF + + I + D+ L+ +++DLQH + S
Sbjct: 2 TSLAILGVGKVGGETAFLSAALGLVDEIVVYDVYEPLLRAQVLDLQH-----TGIDVAIS 56
Query: 307 TDYSITAGSKICVVTAGV-RQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
T+ + + I V AG R + ++R DL++ N V K+ +L++ P ++ + +NP
Sbjct: 57 TETAAMRDADIFVFAAGTPRTPDIKTRADLLEANIPVAKRC-SELLEGFPGVVISV-TNP 114
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSD 594
+D Y WK+ G+ + R IG G+ LDSARF L +
Sbjct: 115 MDANNYGLWKMMGIDRRRCIGFGSQLDSARFAGFLRE 151
>UniRef50_Q4UJ29 Cluster: L-lactate dehydrogenase, putative; n=2;
Theileria|Rep: L-lactate dehydrogenase, putative -
Theileria annulata
Length = 367
Score = 76.6 bits (180), Expect = 5e-13
Identities = 33/111 (29%), Positives = 64/111 (57%)
Frame = +1
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
T T G + A + E +R DLV N+ +++ + + KY+P+ +++ +NP+
Sbjct: 118 TAMECTMGKGARLAKAPTKSNEEWNRDDLVGYNSKIIRDVGENIKKYAPEAFVIVITNPM 177
Query: 487 DILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
D++ ++ K++G PK+ V+G G LDS+R ++++LG+ HG +IG
Sbjct: 178 DVMVHLMLKVTGFPKNMVVGMGGLLDSSRMNCYIAEKLGVNPKYVHGSVIG 228
Score = 39.1 bits (87), Expect = 0.088
Identities = 22/85 (25%), Positives = 44/85 (51%), Gaps = 2/85 (2%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQ-NVTNNIALVDMMADKLKGEMMDLQHGSAFMRNA-KIQSS 306
++++G G +G + LTQ ++ D++ + G+ +D+ H ++ A K + +
Sbjct: 10 ISLIGSGNIGGIMGY--LTQLTELADVNFFDIVPNIGAGKSLDIMHANSIQGKAYKCKGT 67
Query: 307 TDYSITAGSKICVVTAGVRQREGES 381
+Y +GS +C+VTAG E S
Sbjct: 68 NNYEDISGSDVCIVTAGNSYEENNS 92
>UniRef50_Q5FIY9 Cluster: L-LDH; n=6; Lactobacillus|Rep: L-LDH -
Lactobacillus acidophilus
Length = 304
Score = 73.7 bits (173), Expect = 3e-12
Identities = 46/174 (26%), Positives = 89/174 (51%), Gaps = 4/174 (2%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQ-SS 306
KV I+G+G VG A+++ T + + + L+D DK+ E DL+ S N ++ +
Sbjct: 3 KVGIIGMGHVGATVAYTLFTHGIADELVLIDKNEDKVAAEYNDLRD-SLSRNNYYVRVTM 61
Query: 307 TDYSITAGSKICVVTAG---VRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIAS 477
D+ + I V G + G+ R + N K++ ++ +L+ S
Sbjct: 62 QDWHELKDADIIVTAFGDIAASVKTGD-RFGEFELNAKNAKEVGEKIKNTGFKGVLLNIS 120
Query: 478 NPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
NP D + + + +GL K++V+G+GT LD+AR + ++ ++LG + G+++G
Sbjct: 121 NPCDAVAQILQETTGLSKNQVLGTGTFLDTARMQRIIGEKLGQDPKNVEGWVLG 174
>UniRef50_Q6ABQ3 Cluster: L-lactate dehydrogenase; n=1;
Propionibacterium acnes|Rep: L-lactate dehydrogenase -
Propionibacterium acnes
Length = 322
Score = 71.7 bits (168), Expect = 1e-11
Identities = 43/177 (24%), Positives = 91/177 (51%), Gaps = 8/177 (4%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST- 309
+ ++G+G VG + + + I+L+D+ G+ +D H + + A + T
Sbjct: 7 LVVIGIGHVGSDVVTNAAALGLFSRISLIDVDKKVRDGQALD-NHQATAVAPAMTTTITA 65
Query: 310 -DYSITAGSKICVVTAG---VRQREG---ESRLDLVQRNTDVLKQIIPQLIKYSPDTILV 468
+Y + + +V+AG + G +SR L Q N+ V+++++ + +Y+ ++
Sbjct: 66 ANYDACRSADVIIVSAGPSVLPDSYGGGHDSRNSLAQVNSKVIREVMGNICQYTHSAPII 125
Query: 469 IASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+ +NP+D+ ++ P + V+G+GT LDSAR R L+D G++ S +++G
Sbjct: 126 LITNPLDVNVHIAATEFDYPTNLVVGTGTALDSARLRRHLADWAGVSPDSVQAFMLG 182
>UniRef50_Q82R06 Cluster: Putative lactate dehydrogenase; n=1;
Streptomyces avermitilis|Rep: Putative lactate
dehydrogenase - Streptomyces avermitilis
Length = 303
Score = 71.3 bits (167), Expect = 2e-11
Identities = 48/172 (27%), Positives = 84/172 (48%), Gaps = 3/172 (1%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADK---LKGEMMDLQHGSAFMRNAKIQS 303
V +VG G VG A +++ + + +V ++ L ++ D++ + + +
Sbjct: 4 VGVVGAGAVGQTVAATLVASGICPRLLVVSRTVEQARALAADLDDMRQTTGSPVQPEARR 63
Query: 304 STDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
D + V A R + R+ N V++ + L Y T+LV+ +NP
Sbjct: 64 VADLIGCHAVVVAVRAAFTNTRAADVRMGGALTNAPVIRALATTLRGYQ-GTVLVV-TNP 121
Query: 484 VDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
VD++T + + SG P RV G G+NLDSAR+R L+ L + T+ HG++IG
Sbjct: 122 VDLMTRLFAETSGCP--RVYGIGSNLDSARYRLTLAHLLDVPATTVHGHVIG 171
>UniRef50_Q7MTK2 Cluster: Malate dehydrogenase; n=4;
Bacteroidales|Rep: Malate dehydrogenase - Porphyromonas
gingivalis (Bacteroides gingivalis)
Length = 334
Score = 66.9 bits (156), Expect = 4e-10
Identities = 51/164 (31%), Positives = 79/164 (48%), Gaps = 2/164 (1%)
Frame = +1
Query: 121 TWSKVTIVGV-GQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKI 297
T K+TIVG G +G A + +T N+ L D A L+G +++H N
Sbjct: 5 TEEKLTIVGAAGMIGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAEEIRHCGFEGLNLTF 64
Query: 298 QSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPD-TILVIA 474
S ++T +K V + G ++EG +R DL++ N ++ Q+ + Y PD ++I
Sbjct: 65 TSDIKEALT-DAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIII 123
Query: 475 SNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGI 606
NP DI VT SGL K + + LDS R + L+ GI
Sbjct: 124 FNPADITGLVTLIYSGL-KPSQVTTLAGLDSTRLQSELAKHFGI 166
>UniRef50_Q64YY6 Cluster: Malate dehydrogenase; n=5;
Bacteroidales|Rep: Malate dehydrogenase - Bacteroides
fragilis
Length = 333
Score = 62.9 bits (146), Expect = 6e-09
Identities = 48/155 (30%), Positives = 74/155 (47%), Gaps = 2/155 (1%)
Frame = +1
Query: 121 TWSKVTIVGV-GQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKI 297
T K+TIVG G +G A + L +T NI L D A L+G +L H AF
Sbjct: 5 TNEKLTIVGAAGMIGSNMAQTALMMKLTPNICLYDPYAPALEGVAEELYH-CAFEGVNLT 63
Query: 298 QSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDT-ILVIA 474
+S +G+K V + G ++ G +R DL++ N ++ Q + +Y PD +V+
Sbjct: 64 YTSDIKEALSGAKYIVSSGGAARKAGMTREDLLKGNAEIAAQFGKDIRQYCPDVKHVVVV 123
Query: 475 SNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFR 579
NP DI + +GL K + + LDS R +
Sbjct: 124 FNPADITGLIVLLYAGL-KPSQVSTLAALDSTRLQ 157
>UniRef50_Q0PQR8 Cluster: Malate dehydrogenase NAD-dependent; n=1;
Endoriftia persephone 'Hot96_1+Hot96_2'|Rep: Malate
dehydrogenase NAD-dependent - Endoriftia persephone
'Hot96_1+Hot96_2'
Length = 170
Score = 62.9 bits (146), Expect = 6e-09
Identities = 27/84 (32%), Positives = 49/84 (58%)
Frame = +1
Query: 388 DLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDS 567
DL+ N V K++ + +++PD +++ +NP+D + Y K+SGLP R+IG LD+
Sbjct: 17 DLLDINLSVTKKVATAVKQHAPDAFVILTTNPLDSIVYAFHKLSGLPAERIIGMAGALDT 76
Query: 568 ARFRYLLSDRLGIATTSCHGYIIG 639
ARFR ++ G++ ++G
Sbjct: 77 ARFRTYIAMETGLSVKDVSCLVMG 100
>UniRef50_A2SR33 Cluster: Lactate/malate dehydrogenase; n=1;
Methanocorpusculum labreanum Z|Rep: Lactate/malate
dehydrogenase - Methanocorpusculum labreanum (strain
ATCC 43576 / DSM 4855 / Z)
Length = 283
Score = 59.7 bits (138), Expect = 6e-08
Identities = 46/170 (27%), Positives = 81/170 (47%), Gaps = 1/170 (0%)
Frame = +1
Query: 133 VTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTD 312
V +GVG++G A+ + + + L D+ + +D+ HG I ST+
Sbjct: 4 VACLGVGRIGGEVAYVSALRKFADELVLFDISEPLQHAQKLDIIHGM------DIPVSTN 57
Query: 313 YSITAGSKICVVTAGV-RQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
+ + C+ +AG R ++R DL +N + K+ L +S L++ +NP+D
Sbjct: 58 PADLKDADYCIFSAGYSRSPNIKTRADLFDKNLPIAKESSELLKGFSGK--LIVVTNPMD 115
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
+ T+ K S L + +V+G G LDS RF +L +GI G ++G
Sbjct: 116 VFTWYFAKKSCLDESQVVGFGGLLDSRRFTVVLRS-IGI---EAEGQVLG 161
>UniRef50_A5IYS9 Cluster: L-lactate dehydrogenase; n=2;
Mycoplasma|Rep: L-lactate dehydrogenase - Mycoplasma
agalactiae
Length = 323
Score = 58.4 bits (135), Expect = 1e-07
Identities = 39/173 (22%), Positives = 78/173 (45%), Gaps = 3/173 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFM-RNAK-IQS 303
K+ +VG+G VG + + + + LVD + D + + M RN +
Sbjct: 3 KIIVVGLGNVGFTYINTSVARGLEAEWVLVDKNVQIAEAHAHDFEDMVSLMPRNGSTFRP 62
Query: 304 STDYSITAGSKICVVTAGV-RQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
T + + + V+TA + + R+ L N +++ L I+V+A+N
Sbjct: 63 GTLLEDSKDADVVVITASIPADKTFSDRMALAGANAKLMQSFAKDLDAAGFKGIVVVAAN 122
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
P D++ S +P +RVI +GTNL++ R + +L+ + + + ++G
Sbjct: 123 PCDVMAAAVHYGSKIPANRVISAGTNLETGRLKKMLAAKFNTSPDAIRASVLG 175
>UniRef50_A7TL95 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 365
Score = 58.4 bits (135), Expect = 1e-07
Identities = 49/164 (29%), Positives = 85/164 (51%), Gaps = 7/164 (4%)
Frame = +1
Query: 130 KVTIVGV-GQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
KV ++G G +G + + +++AL D+ +D G DL H + +
Sbjct: 3 KVCVLGASGGIGQPLSLLLKLNPYVSDLALYDI-SDITAGVAKDLSHINTNSDSEGYNKD 61
Query: 307 TDY-SITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSP-DTILVIASN 480
D+ ++ GS++ +VTAG+ ++ G +R DL + N +++ + + K++P L+I SN
Sbjct: 62 EDFKNLLEGSELVIVTAGIPRKPGMTRDDLFKINAKIIQNLTVKYAKFAPVHCKLLIISN 121
Query: 481 PVDILTYV---TWKISG-LPKHRVIGSGTNLDSARFRYLLSDRL 600
PV+ L V T KI+G L +V G T LD R + L+D L
Sbjct: 122 PVNSLIPVVIETLKINGRLNPSQVFGI-TMLDIIRSQTFLNDLL 164
>UniRef50_Q1U8H4 Cluster: L-lactate dehydrogenase; n=2;
Lactobacillus reuteri|Rep: L-lactate dehydrogenase -
Lactobacillus reuteri 100-23
Length = 307
Score = 56.8 bits (131), Expect = 4e-07
Identities = 40/173 (23%), Positives = 82/173 (47%), Gaps = 3/173 (1%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVD---MMADKLKGEMMDLQHGSAFMRNAKIQ 300
K+ I+G+G VG A ++ + + L+D +A ++ ++ D Q A IQ
Sbjct: 3 KIGIIGLGHVGEMLANQLVMNGKVDELVLIDEKDQLAIAIQADLNDAQTVLATHTKIIIQ 62
Query: 301 SSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN 480
DY+ A + + + G + + ++ + Q+ ++ K IL+ +N
Sbjct: 63 ---DYAALADADVLITAFGKSALMKQQPMAELETSYQQALQVGNKVFKSDFSGILINLTN 119
Query: 481 PVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
P + +T V + GLP+ +VIG GT +++AR +++ +A + G++ G
Sbjct: 120 PNEAITAVLQQKVGLPQKQVIGIGTVVETARLYRAIAEAAKVAAANVTGFVYG 172
>UniRef50_Q4Q3J3 Cluster: Malate dehydrogenase, putative; n=3;
Leishmania|Rep: Malate dehydrogenase, putative -
Leishmania major
Length = 331
Score = 56.4 bits (130), Expect = 5e-07
Identities = 39/162 (24%), Positives = 81/162 (50%), Gaps = 4/162 (2%)
Frame = +1
Query: 130 KVTIVGV-GQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
KVT++G G +G A +++ + +AL D++ + G +DL H ++ +
Sbjct: 10 KVTVLGASGAIGQPLALALVQNKRVSELALYDIVQPR--GVAVDLSHFPRKVKVTGYPTK 67
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPV 486
+ G+ + +++AG+ +R G + DL N + ++ + +Y+P ++L I SNP+
Sbjct: 68 WIHKALDGADLVLMSAGMPRRPGMTHDDLFNTNALTVNELSAAVARYAPKSVLAIISNPL 127
Query: 487 DILTYV---TWKISGLPKHRVIGSGTNLDSARFRYLLSDRLG 603
+ + V T + +G+ R + +L+ R R +L D G
Sbjct: 128 NSMVPVAAETLQRAGVYDPRKLFGIISLNMMRARKMLGDFTG 169
>UniRef50_Q86S07 Cluster: NAD-specific malate dehydrogenase 2; n=1;
Entamoeba histolytica|Rep: NAD-specific malate
dehydrogenase 2 - Entamoeba histolytica
Length = 329
Score = 52.8 bits (121), Expect = 7e-06
Identities = 52/189 (27%), Positives = 85/189 (44%), Gaps = 8/189 (4%)
Frame = +1
Query: 94 QPVH-EKVDETWS-KVTIVGV-GQVGMAAAFSM---LTQNVTNNIALVDMMADKLKGEMM 255
QP+ EKV+ T V I G GQ+G F + + + L D+ LKG M
Sbjct: 3 QPIPWEKVNRTEPLHVLITGAAGQIGYNLCFLIGRGFLFDCDVILHLYDLNDMALKGLSM 62
Query: 256 DLQHGSAFMRNAKIQSSTDYSITAGS-KICVVTAGVRQREGESRLDLVQRNTDVLKQIIP 432
+L + I S+T+ ++ + + ++ AGV ++ G R DL+ N V++
Sbjct: 63 ELTD-CCLPKLKGIISTTEIALAFSNVDVAIIVAGVPRKPGMQRSDLINVNKKVMEMNGK 121
Query: 433 QLIKYS-PDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIA 609
L YS D +V+ +NP + YV K SG+P + T LD R +++ +G
Sbjct: 122 ALGTYSNKDVRVVVVANPANTNAYVICKTSGIPPEHITAL-TRLDQNRATAFVANEVGCQ 180
Query: 610 TTSCHGYII 636
H I+
Sbjct: 181 PEFVHNIIV 189
>UniRef50_Q5ENS5 Cluster: Malate dehydrogenase; n=1; Heterocapsa
triquetra|Rep: Malate dehydrogenase - Heterocapsa
triquetra (Dinoflagellate)
Length = 402
Score = 47.2 bits (107), Expect = 3e-04
Identities = 27/85 (31%), Positives = 46/85 (54%), Gaps = 3/85 (3%)
Frame = +1
Query: 328 GSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYV- 504
G + ++ AG+ ++ G++R DL + N D+ K I+ KY PD +L + NPV+ +
Sbjct: 158 GCHLVLIPAGMPRKPGQTRDDLFKINADIAKGIVEACAKYCPDAMLGMIVNPVNSVVPAM 217
Query: 505 --TWKISGLPKHRVIGSGTNLDSAR 573
+K GL +++G T LD R
Sbjct: 218 AELYKKKGLDPMKIVGI-TTLDVVR 241
>UniRef50_Q8Y860 Cluster: Lmo1057 protein; n=11; Listeria|Rep:
Lmo1057 protein - Listeria monocytogenes
Length = 317
Score = 44.8 bits (101), Expect = 0.002
Identities = 35/170 (20%), Positives = 82/170 (48%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST 309
K+ ++G + ++L + + I L+D D+ K + D + S + + I S T
Sbjct: 7 KIVVIGRSNLQNLYIHTVLLKKLPAEIYLID---DQAKTSVQDFDYASYYHADVTIHSGT 63
Query: 310 DYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVD 489
++ + I V Q E +++ + N ++ + + +++ I+++A+ +
Sbjct: 64 -FNECRNADIVVFF----QEEMSNQIVSKEDNVALIIEKVKKMMATGFRGIVLVATAESN 118
Query: 490 ILTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
++ + + SGL +++I GT L ++ F+ ++ I+ + HGYIIG
Sbjct: 119 VVAALIKRFSGLSANQIITLGTMLATSYFQVEIAKLFKISPKNVHGYIIG 168
>UniRef50_UPI0000DB76D8 Cluster: PREDICTED: similar to CG7998-PA;
n=2; Apis mellifera|Rep: PREDICTED: similar to CG7998-PA
- Apis mellifera
Length = 333
Score = 41.1 bits (92), Expect = 0.022
Identities = 24/96 (25%), Positives = 49/96 (51%), Gaps = 3/96 (3%)
Frame = +1
Query: 328 GSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVT 507
G+KI ++ V R ++++ N +L ++P +IK+SP +L I NP++ L +T
Sbjct: 70 GAKIVMI---VTDRTSNESNEVLKSNAIILSDLLPNIIKFSPQAMLAIVMNPINSLIPLT 126
Query: 508 ---WKISGLPKHRVIGSGTNLDSARFRYLLSDRLGI 606
+K +G+ ++ I N + + +D + I
Sbjct: 127 MEMYKKAGIYEYNRIFGVMNFECLKANSFTADLINI 162
>UniRef50_Q039N1 Cluster: Malate/lactate dehydrogenase; n=1;
Lactobacillus casei ATCC 334|Rep: Malate/lactate
dehydrogenase - Lactobacillus casei (strain ATCC 334)
Length = 296
Score = 41.1 bits (92), Expect = 0.022
Identities = 19/84 (22%), Positives = 41/84 (48%)
Frame = +1
Query: 388 DLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNLDS 567
D ++ N +++++ + +++A ++ TY + SG+ K +V+G GT +
Sbjct: 81 DFIETNIAAIRKVLNSAMAAGFTGRIIVAMTRDELFTYFAQRFSGVNKSQVVGLGTFGAT 140
Query: 568 ARFRYLLSDRLGIATTSCHGYIIG 639
RF L+ RL + Y++G
Sbjct: 141 WRFEQFLAARLAVPAKHVTAYVVG 164
>UniRef50_Q01JC3 Cluster: Malate dehydrogenase; n=8; cellular
organisms|Rep: Malate dehydrogenase - Oryza sativa
(Rice)
Length = 352
Score = 41.1 bits (92), Expect = 0.022
Identities = 34/158 (21%), Positives = 71/158 (44%), Gaps = 3/158 (1%)
Frame = +1
Query: 142 VGVGQVGMAAAFSMLTQNVTNNIALVDM--MADKLKGEMMDLQHGSAFMRNAKIQSSTDY 315
+G V M A ML + + L+D+ A+ L G M+L + + + +S +
Sbjct: 38 IGYAIVAMIAKGLMLGADQPVVLHLLDLPVAANALNGVRMELIDAALPLLRGVVATSDEA 97
Query: 316 SITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKY-SPDTILVIASNPVDI 492
G + ++ G +R+G R DL+ +N + K L ++ +P+ +++ +NP +
Sbjct: 98 EAFKGVNVAILIGGWPRRDGMERKDLISKNVTIYKSQASALQQHAAPNCKVLVVANPANT 157
Query: 493 LTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGI 606
V + + + I T LD R ++++L +
Sbjct: 158 NALVLKEFAPAIPAKNITCLTRLDHNRALGQVAEKLNV 195
>UniRef50_Q75AT4 Cluster: ADL164Cp; n=2; Saccharomycetales|Rep:
ADL164Cp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 381
Score = 39.5 bits (88), Expect = 0.067
Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 8/112 (7%)
Frame = +1
Query: 193 NVTNNIALVDMMADKLKGEMMDLQHGSAFMR-NAKIQSSTD-----YSITAGSKICVVTA 354
N + +AL D+ AD L G DL H + + + + SS + G+ + V+ A
Sbjct: 55 NASLELALYDVAADALAGVAADLSHVNTPVEVSHHVPSSREDEEALREALTGASVVVIPA 114
Query: 355 GVRQREGESRLDLVQRNTDVLKQIIPQLIKYS--PDTILVIASNPVDILTYV 504
GV ++ G +R DL+ N ++K + + +++ SNPV+ L V
Sbjct: 115 GVPRKPGMTRDDLININAGIIKTLAKGIAGACDLEKVFVLVISNPVNSLVPV 166
>UniRef50_Q9VU29 Cluster: Malate dehydrogenase; n=5;
Protostomia|Rep: Malate dehydrogenase - Drosophila
melanogaster (Fruit fly)
Length = 347
Score = 39.1 bits (87), Expect = 0.088
Identities = 38/175 (21%), Positives = 71/175 (40%), Gaps = 5/175 (2%)
Frame = +1
Query: 130 KVTIVG-VGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
KV +VG VG +G + + + ++L D+ G +DL H + +
Sbjct: 29 KVAVVGSVGGIGQPLSLLLKHNPQISTLSLYDIK--NTTGVGVDLSHINTRASVCPFEGK 86
Query: 307 TDYSITAG-SKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP 483
+ I V+ AG+ ++ G R DLV N V ++ + P +L +NP
Sbjct: 87 NGLKKAMDKADIVVIPAGLPRKPGMKREDLVDVNASVACEVAFAASEVCPGAMLAFITNP 146
Query: 484 VDILTYVT---WKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
++++ + K G + T LD R + ++D L + + +IG
Sbjct: 147 INVIVPIVATILKAKGTYDPNRLFGVTTLDVVRAQTFVADILNVDPQKVNIPVIG 201
>UniRef50_P40925 Cluster: Malate dehydrogenase, cytoplasmic; n=124;
cellular organisms|Rep: Malate dehydrogenase,
cytoplasmic - Homo sapiens (Human)
Length = 334
Score = 39.1 bits (87), Expect = 0.088
Identities = 39/179 (21%), Positives = 77/179 (43%), Gaps = 10/179 (5%)
Frame = +1
Query: 130 KVTIVGV-GQVGMAAAFSMLTQNVTNN-----IALVDM--MADKLKGEMMDLQHGSAFMR 285
+V + G GQ+ + +S+ +V + L+D+ M L G +M+LQ + +
Sbjct: 6 RVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPLL 65
Query: 286 NAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTI- 462
I + + + ++ + +REG R DL++ N + K L KY+ ++
Sbjct: 66 KDVIATDKEDVAFKDLDVAILVGSMPRREGMERKDLLKANVKIFKSQGAALDKYAKKSVK 125
Query: 463 LVIASNPVDILTYVTWKIS-GLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYII 636
+++ NP + K + +PK T LD R + ++ +LG+ II
Sbjct: 126 VIVVGNPANTNCLTASKSAPSIPKEN-FSCLTRLDHNRAKAQIALKLGVTANDVKNVII 183
>UniRef50_Q6CP51 Cluster: Similar to sp|P22133 Saccharomyces
cerevisiae YOL126c MDH2 malate dehydrogenase; n=1;
Kluyveromyces lactis|Rep: Similar to sp|P22133
Saccharomyces cerevisiae YOL126c MDH2 malate
dehydrogenase - Kluyveromyces lactis (Yeast) (Candida
sphaerica)
Length = 404
Score = 37.5 bits (83), Expect = 0.27
Identities = 25/102 (24%), Positives = 49/102 (48%), Gaps = 6/102 (5%)
Frame = +1
Query: 208 IALVDMMADKLKGEMMDLQH-GSAFMRNAKIQSSTDYSI---TAGSKICVVTAGVRQREG 375
++L D+ D + G DL H + A ++ I + + + ++ AGV ++ G
Sbjct: 84 LSLYDVNKDAIVGTAADLSHIDTPITTTAHYPDDSNGGIGQCLSNASVVIIPAGVPRKPG 143
Query: 376 ESRLDLVQRNTDVLKQIIPQLIKYSP--DTILVIASNPVDIL 495
SR DL+ N ++K + + KY +++ SNP++ L
Sbjct: 144 MSRDDLIGVNAKIIKSLGEDIAKYCDLNKVHVLVISNPINSL 185
>UniRef50_Q0JBC2 Cluster: Os04g0542900 protein; n=8;
Magnoliophyta|Rep: Os04g0542900 protein - Oryza sativa
subsp. japonica (Rice)
Length = 519
Score = 37.1 bits (82), Expect = 0.36
Identities = 30/78 (38%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
Frame = +3
Query: 66 QDGVPEEAVPARAREGGRNLEQGDHCRGRSGWDGRSFLYADAECYE*--HRSSRHDG*QI 239
+D P PAR E GR GD R RS W + E E HR+SR DG Q
Sbjct: 84 EDDAPRRHRPAREEEEGR----GDE-RSRSTWAEVVSDHKGGEAEERPDHRNSRRDGRQ- 137
Query: 240 ERRDDGPAARISIHEERQ 293
ERR+DG R+ ++ Q
Sbjct: 138 ERREDGDWERVDGRKQHQ 155
>UniRef50_UPI0000DB7CDC Cluster: PREDICTED: similar to CTD
(carboxy-terminal domain, RNA polymerase II, polypeptide
A) small phosphatase like 2; n=1; Apis mellifera|Rep:
PREDICTED: similar to CTD (carboxy-terminal domain, RNA
polymerase II, polypeptide A) small phosphatase like 2 -
Apis mellifera
Length = 486
Score = 36.7 bits (81), Expect = 0.47
Identities = 27/89 (30%), Positives = 43/89 (48%), Gaps = 7/89 (7%)
Frame = -3
Query: 422 CLRTSVFLCTRSRRDSPSRCRTPAVTTQIFEPAVIE*SVLDW------ILAFLMNADPCC 261
C++ S+ T R S TPA T + + V E S +W + + ++N D CC
Sbjct: 97 CIKRSMVTSTPLHRTSTKNAVTPAKCTTVSK--VSEESKENWNVTSLSLYSSILNTDTCC 154
Query: 260 RSIISPFNL-SAIMSTRAMLFVTFCVSIE 177
SI S + S+I +TR++ + T C E
Sbjct: 155 SSISSVNDFKSSISNTRSLYYSTSCSQTE 183
>UniRef50_Q2QQV8 Cluster: Retrotransposon protein, putative,
unclassified; n=7; Oryza sativa|Rep: Retrotransposon
protein, putative, unclassified - Oryza sativa subsp.
japonica (Rice)
Length = 1621
Score = 36.3 bits (80), Expect = 0.62
Identities = 19/57 (33%), Positives = 28/57 (49%)
Frame = +3
Query: 45 HGTLTEPQDGVPEEAVPARAREGGRNLEQGDHCRGRSGWDGRSFLYADAECYE*HRS 215
H LTEP+ G PEE V + R ++G+ ++G + LY DA HR+
Sbjct: 307 HPKLTEPEKGGPEEGVGGKRRRSAGGGDEGEKPTKKAGLAIQPCLYGDAHSETKHRT 363
>UniRef50_Q1WU75 Cluster: Lactate/malate dehydrogenase; n=1;
Lactobacillus salivarius subsp. salivarius UCC118|Rep:
Lactate/malate dehydrogenase - Lactobacillus salivarius
subsp. salivarius (strain UCC118)
Length = 294
Score = 35.9 bits (79), Expect = 0.82
Identities = 22/86 (25%), Positives = 46/86 (53%)
Frame = +1
Query: 382 RLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHRVIGSGTNL 561
R + Q+N+ + K ++ + + + I+V+ SN +L K +GL +V+G GT++
Sbjct: 80 RDNFAQKNSWIQK-VVTEAVANGFNGIVVLDSNKDYLLINEILKYTGLSSRQVLGLGTSI 138
Query: 562 DSARFRYLLSDRLGIATTSCHGYIIG 639
+S +++ +LGI + +IG
Sbjct: 139 ESEVVARMVAKKLGINSNYIQTSVIG 164
>UniRef50_Q08W33 Cluster: Serine/threonine-protein kinase Pkn6; n=2;
Stigmatella aurantiaca DW4/3-1|Rep:
Serine/threonine-protein kinase Pkn6 - Stigmatella
aurantiaca DW4/3-1
Length = 958
Score = 35.1 bits (77), Expect = 1.4
Identities = 20/46 (43%), Positives = 27/46 (58%)
Frame = -1
Query: 166 PSQPDRPRQWSPCSKFRPPSRARAGTASSGTPSCGSVSVPWDWSRS 29
P +P P + SP S RP + GTASSGTP+ VS+ + SR+
Sbjct: 474 PPRPGEPPRASPGSAARPAGSSVPGTASSGTPA--YVSLAMEMSRA 517
>UniRef50_Q03QL8 Cluster: Malate/lactate dehydrogenase; n=1;
Lactobacillus brevis ATCC 367|Rep: Malate/lactate
dehydrogenase - Lactobacillus brevis (strain ATCC 367 /
JCM 1170)
Length = 302
Score = 34.7 bits (76), Expect = 1.9
Identities = 16/49 (32%), Positives = 26/49 (53%)
Frame = +1
Query: 493 LTYVTWKISGLPKHRVIGSGTNLDSARFRYLLSDRLGIATTSCHGYIIG 639
L+Y WK SGL +++ G GT + L+D LG+ + + +IG
Sbjct: 117 LSYFAWKFSGLQANQIWGLGTYPLARLLTARLADHLGVGSAAVQATVIG 165
>UniRef50_Q7G3D9 Cluster: Retrotransposon protein, putative,
unclassified; n=5; Oryza sativa|Rep: Retrotransposon
protein, putative, unclassified - Oryza sativa subsp.
japonica (Rice)
Length = 1505
Score = 34.7 bits (76), Expect = 1.9
Identities = 18/57 (31%), Positives = 28/57 (49%)
Frame = +3
Query: 45 HGTLTEPQDGVPEEAVPARAREGGRNLEQGDHCRGRSGWDGRSFLYADAECYE*HRS 215
H LT+P+ G PEE V + R ++G+ ++G + LY DA HR+
Sbjct: 348 HPKLTKPEKGGPEEGVGGKRRRSAGGGDEGEKPTKKAGLAIQPCLYGDAHSETKHRT 404
>UniRef50_UPI0000E45EC5 Cluster: PREDICTED: similar to CG10662-PA;
n=1; Strongylocentrotus purpuratus|Rep: PREDICTED:
similar to CG10662-PA - Strongylocentrotus purpuratus
Length = 217
Score = 34.3 bits (75), Expect = 2.5
Identities = 30/115 (26%), Positives = 56/115 (48%), Gaps = 8/115 (6%)
Frame = +1
Query: 94 QPVHEKVDETWSKVTIVGV-GQVG-------MAAAFSMLTQNVTNNIALVDMMADKLKGE 249
Q + E+ TWS+ ++ G+VG + AAF N+TN + + AD+ GE
Sbjct: 84 QHIRERTWSTWSRHSVHSTTGRVGSLGGRAHVVAAFEQSLSNMTNRLQRLTSTADQKDGE 143
Query: 250 MMDLQHGSAFMRNAKIQSSTDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDV 414
+ DL+ ++ A I ++T ++ G ++ G + +S +L + NT+V
Sbjct: 144 LQDLREKIEQLKVAHI-TNTQGLLSNG-----LSNGALNGQKKSSGNLTRENTEV 192
>UniRef50_A0QSN0 Cluster: Ftsk/spoiiie family protein; n=1;
Mycobacterium smegmatis str. MC2 155|Rep: Ftsk/spoiiie
family protein - Mycobacterium smegmatis (strain ATCC
700084 / mc(2)155)
Length = 1211
Score = 34.3 bits (75), Expect = 2.5
Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 2/64 (3%)
Frame = +1
Query: 145 GVGQVGMAAA--FSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTDYS 318
G +G+A+A S L N+++ A+V MAD L GEM Q +R A + S+ +Y+
Sbjct: 443 GATFLGLASAPHISALITNLSDEAAMVARMADALAGEMTRRQE---LLRAANVGSAAEYT 499
Query: 319 ITAG 330
T G
Sbjct: 500 RTNG 503
>UniRef50_A2YRW8 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. indica (Rice)
Length = 127
Score = 34.3 bits (75), Expect = 2.5
Identities = 18/46 (39%), Positives = 31/46 (67%), Gaps = 4/46 (8%)
Frame = +1
Query: 379 SRLDLVQRN--TDVLKQIIPQLIKYSPDTILVIASNPV--DILTYV 504
++L+L++ N +L +I+P L + SP+ LV+ S+P D+LTYV
Sbjct: 3 TKLELMRSNYLKKLLTEIVPALAENSPEAALVVVSDPPVDDVLTYV 48
>UniRef50_Q8EYH1 Cluster: Methyl-accepting chemotaxis protein; n=2;
Leptospira interrogans|Rep: Methyl-accepting chemotaxis
protein - Leptospira interrogans
Length = 530
Score = 33.9 bits (74), Expect = 3.3
Identities = 20/55 (36%), Positives = 33/55 (60%), Gaps = 1/55 (1%)
Frame = -3
Query: 551 PDPMTRCLGSPLIFHVTYVRI-STGLLAITNIVSGLYFISCGIICLRTSVFLCTR 390
PD T + SP+++ ++Y+ I S+GLL + N V + F+S G L ++F TR
Sbjct: 105 PDFTTGVVKSPILYGISYMYIVSSGLLLVPNFVLWIGFLSGGAQAL--AIFTATR 157
>UniRef50_A0W7C0 Cluster: Diguanylate cyclase/phosphodiesterase with
PAS/PAC sensor; n=2; cellular organisms|Rep: Diguanylate
cyclase/phosphodiesterase with PAS/PAC sensor -
Geobacter lovleyi SZ
Length = 1027
Score = 33.9 bits (74), Expect = 3.3
Identities = 22/72 (30%), Positives = 36/72 (50%), Gaps = 1/72 (1%)
Frame = +1
Query: 364 QREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASNP-VDILTYVTWKISGLPKHRV 540
QRE ++ V++ +Q + +I + PD + VI N V I K+SG+PK +
Sbjct: 318 QREQLAKARAVEQALLDARQQLNDIIDFFPDAVFVIDRNKRVTIWNRAIEKMSGVPKEEM 377
Query: 541 IGSGTNLDSARF 576
+G G + S F
Sbjct: 378 LGKGDHEYSIPF 389
>UniRef50_A1S187 Cluster: UBA/THIF-type NAD/FAD binding protein;
n=2; Archaea|Rep: UBA/THIF-type NAD/FAD binding protein
- Thermofilum pendens (strain Hrk 5)
Length = 256
Score = 33.9 bits (74), Expect = 3.3
Identities = 26/97 (26%), Positives = 46/97 (47%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
S V +VG G +G AF ++ V + +VD +L + H ++ + AK++S+
Sbjct: 30 STVLVVGAGGLGSPVAFYLVAAGV-GKLIIVDAEDVELSNLNRQILHWTSDLGKAKVESA 88
Query: 307 TDYSITAGSKICVVTAGVRQREGESRLDLVQRNTDVL 417
+ + VVT + R E L LV+ + DV+
Sbjct: 89 KEKLEKLNPHVEVVTLKQKIRSLEDALKLVE-DADVV 124
>UniRef50_UPI000155BE55 Cluster: PREDICTED: similar to CENPE variant
protein, partial; n=1; Ornithorhynchus anatinus|Rep:
PREDICTED: similar to CENPE variant protein, partial -
Ornithorhynchus anatinus
Length = 746
Score = 33.5 bits (73), Expect = 4.4
Identities = 22/108 (20%), Positives = 49/108 (45%), Gaps = 3/108 (2%)
Frame = +1
Query: 1 ETQTLTNSKHYVTSPTER*LNHKMESLKKLFQPVHEKVDETWSKVTIVGVGQVGMAAAFS 180
E Q L + + T+ E L + L + + +HEK+D+ +++ ++ + +AA
Sbjct: 601 EQQELVTKERHETAEKEAELLRTHKKLTETEEKLHEKIDDLTNELNVINAEKQRVAAKLE 660
Query: 181 MLTQNV---TNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTDY 315
+ + V IA + D L+ +++ A++Q ST++
Sbjct: 661 VENEQVEQLKKQIASIQQERDHLQ-NLLEAASAEKSQLQARLQKSTEW 707
>UniRef50_Q15ST6 Cluster: UBA/THIF-type NAD/FAD binding fold; n=2;
Alteromonadales|Rep: UBA/THIF-type NAD/FAD binding fold
- Pseudoalteromonas atlantica (strain T6c / BAA-1087)
Length = 256
Score = 33.5 bits (73), Expect = 4.4
Identities = 23/74 (31%), Positives = 38/74 (51%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSS 306
SKV I+GVG +G AAA +++ + I LVD +L + H + K+ S+
Sbjct: 37 SKVLIIGVGGLGCAAAQYLVSSGI-GEITLVDDDKVELSNLHRQVLHHEQDVGVKKVDSA 95
Query: 307 TDYSITAGSKICVV 348
S+ A + +CV+
Sbjct: 96 KT-SLLANNSLCVI 108
>UniRef50_Q9VQF9 Cluster: CG9958-PA, isoform A; n=2; Sophophora|Rep:
CG9958-PA, isoform A - Drosophila melanogaster (Fruit
fly)
Length = 134
Score = 33.5 bits (73), Expect = 4.4
Identities = 22/95 (23%), Positives = 47/95 (49%)
Frame = +1
Query: 19 NSKHYVTSPTER*LNHKMESLKKLFQPVHEKVDETWSKVTIVGVGQVGMAAAFSMLTQNV 198
N++++ T+PT L E + LF+P E++DE + + G A + +++
Sbjct: 13 NTENFCTNPTRDIL---AEGITNLFKPTIERLDERVASTIQLQAELRGQLDALAAQLRDI 69
Query: 199 TNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQS 303
+ + ADK+K E+++++H + N + S
Sbjct: 70 EKAQSQIPEFADKVK-ELLNVKHKVTVISNVLVTS 103
>UniRef50_Q45614 Cluster: Sensor protein yycG; n=34; Bacillales|Rep:
Sensor protein yycG - Bacillus subtilis
Length = 611
Score = 33.5 bits (73), Expect = 4.4
Identities = 43/160 (26%), Positives = 69/160 (43%), Gaps = 11/160 (6%)
Frame = +1
Query: 163 MAAAFSMLTQNVTNN-IALVDMMADKLKGEMMDLQHGSAFMRNAKIQSST--DYSITAGS 333
+A F M+TQN T I LV+ + K + D Q +++ + S + +T
Sbjct: 412 IAPRFLMVTQNETERMIRLVNDLLQLSKFDSKDYQFNREWIQIVRFMSLIIDRFEMTKEQ 471
Query: 334 KICVVTAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPD---TILVIASNPVDILTYV 504
+ + + R+ +D + T VL II +KYSP+ I N + L Y+
Sbjct: 472 HVEFIR-NLPDRDLYVEIDQ-DKITQVLDNIISNALKYSPEGGHVTFSIDVNEEEELLYI 529
Query: 505 TWKIS--GLPK---HRVIGSGTNLDSARFRYLLSDRLGIA 609
+ K G+PK +V +D AR R L LG+A
Sbjct: 530 SVKDEGIGIPKKDVEKVFDRFYRVDKARTRKLGGTGLGLA 569
>UniRef50_Q55GH1 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 477
Score = 33.1 bits (72), Expect = 5.8
Identities = 53/197 (26%), Positives = 86/197 (43%), Gaps = 7/197 (3%)
Frame = +1
Query: 4 TQTLTNSKHYVTSPT---ER*LNHKMESLKKLF-QPVHEKVDETWSKVTIVGVGQVGMAA 171
T T TN K + + E N +M+ K + + EK+ E++ V +VG+G VG AA
Sbjct: 72 TATTTNKKESLNLDSLLQEEIFNEQMDRTKLYYGEEGFEKIRESF--VVVVGLGGVGGAA 129
Query: 172 AFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRNAKIQSSTDYSITAGSKICVVT 351
A +L V + L+D DL S+ RNA + + D SK+ V+
Sbjct: 130 AHVLLRSGV-KKLRLID----------PDLVTLSSLNRNA-LATRND---VGRSKVEVMK 174
Query: 352 AGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTILVIASN---PVDILTYVTWKISG 522
E ++ +Q T ++ P+L+ PD +L N V++LTY K
Sbjct: 175 QHFHDICPEVEVEAIQ--TFFTGELAPKLLHGKPDYVLDCIDNTQTKVELLTYC--KREN 230
Query: 523 LPKHRVIGSGTNLDSAR 573
L G+G++ D +
Sbjct: 231 LRVISSFGAGSSSDPTK 247
>UniRef50_Q6NYY8 Cluster: Smox protein; n=12; Coelomata|Rep: Smox
protein - Danio rerio (Zebrafish) (Brachydanio rerio)
Length = 539
Score = 32.7 bits (71), Expect = 7.7
Identities = 14/47 (29%), Positives = 26/47 (55%)
Frame = +1
Query: 130 KVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHG 270
++ ++G G G+AA ++L TN L +D++ G + +QHG
Sbjct: 26 RIVVIGAGLAGLAATKTLLENGFTNVTVL--EASDRIGGRVQSIQHG 70
>UniRef50_Q8FY97 Cluster: Prephenate dehydrogenase; n=75;
Bacteria|Rep: Prephenate dehydrogenase - Brucella suis
Length = 321
Score = 32.7 bits (71), Expect = 7.7
Identities = 31/127 (24%), Positives = 58/127 (45%), Gaps = 6/127 (4%)
Frame = +1
Query: 124 WSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKLKGEMMDLQHGSAFMRN-AKIQ 300
+ K+T++G+G +G + A + + + +IA+ A+ LK +L G ++ N A+
Sbjct: 6 FDKITLIGIGLIGSSLARVIRREGLATHIAIATRSAETLK-RAEELNLGDSYTTNSAEAV 64
Query: 301 SSTD---YSITAGSKICVV--TAGVRQREGESRLDLVQRNTDVLKQIIPQLIKYSPDTIL 465
D S+ GS V AG + G D+ V+ Q+ P+L P+ +
Sbjct: 65 KDADLVIVSVPVGSSGTVARQIAG-NLKPGAIVTDVGSTKASVIAQMQPEL----PENVH 119
Query: 466 VIASNPV 486
I +P+
Sbjct: 120 FIPGHPL 126
>UniRef50_Q6ANF8 Cluster: Related to dipeptidase; n=17;
Bacteria|Rep: Related to dipeptidase - Desulfotalea
psychrophila
Length = 404
Score = 32.7 bits (71), Expect = 7.7
Identities = 15/37 (40%), Positives = 19/37 (51%), Gaps = 1/37 (2%)
Frame = +2
Query: 455 TQYW*SPVTPWIF*RMLRGR-LAGCPSTASSGPALTW 562
TQ+W SP PW G+ +A P +SG A TW
Sbjct: 64 TQFWESPTRPWFLIIPTEGKPIAVIPGIGASGMAATW 100
>UniRef50_Q577J1 Cluster: Alcohol dehydrogenase, zinc-containing;
n=36; Bacteria|Rep: Alcohol dehydrogenase,
zinc-containing - Brucella abortus
Length = 375
Score = 32.7 bits (71), Expect = 7.7
Identities = 18/38 (47%), Positives = 22/38 (57%)
Frame = +1
Query: 127 SKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKL 240
S+V I G+G VG+AA + T IAL DM DKL
Sbjct: 195 SRVAIAGLGGVGLAAVMGAVAAGATEIIAL-DMFDDKL 231
>UniRef50_Q15QV8 Cluster: Putative uncharacterized protein; n=1;
Pseudoalteromonas atlantica T6c|Rep: Putative
uncharacterized protein - Pseudoalteromonas atlantica
(strain T6c / BAA-1087)
Length = 295
Score = 32.7 bits (71), Expect = 7.7
Identities = 25/70 (35%), Positives = 37/70 (52%), Gaps = 1/70 (1%)
Frame = +1
Query: 391 LVQRNTDVLKQIIPQLIKYSPDTILVIASNPVDILTYVTWKISGLPKHR-VIGSGTNLDS 567
L+ + + +IPQLI+ +IL I NPVD+L ++W LP +R I +G D
Sbjct: 132 LIVKQNALFTALIPQLIQQF--SILCIVRNPVDVL--LSWFTVDLPVNRGHIPAGERFDE 187
Query: 568 ARFRYLLSDR 597
A R L D+
Sbjct: 188 A-LRLSLQDK 196
>UniRef50_A6EYX5 Cluster: Sensor protein; n=1; Marinobacter algicola
DG893|Rep: Sensor protein - Marinobacter algicola DG893
Length = 1054
Score = 32.7 bits (71), Expect = 7.7
Identities = 27/80 (33%), Positives = 38/80 (47%), Gaps = 6/80 (7%)
Frame = +1
Query: 394 VQRNTDVLKQIIPQLIKYSPD--TILVIA-SNPVDILTYVTWKISGLP---KHRVIGSGT 555
VQR VL ++ IK+SPD T+ + A S DI V + G+P +H+V
Sbjct: 684 VQRLKQVLANLLSNAIKFSPDGGTVSIEATSTDTDITVSVVDQGPGIPEDFQHKVFQKFA 743
Query: 556 NLDSARFRYLLSDRLGIATT 615
DS+ R LG+A T
Sbjct: 744 QADSSDTRQKGGTGLGLAIT 763
>UniRef50_Q6ZCA3 Cluster: Putative uncharacterized protein
P0547A06.25; n=1; Oryza sativa (japonica
cultivar-group)|Rep: Putative uncharacterized protein
P0547A06.25 - Oryza sativa subsp. japonica (Rice)
Length = 187
Score = 32.7 bits (71), Expect = 7.7
Identities = 17/45 (37%), Positives = 30/45 (66%), Gaps = 4/45 (8%)
Frame = +1
Query: 379 SRLDLVQRN--TDVLKQIIPQLIKYSPDTILVIASNPV--DILTY 501
++L+L++ N +L +I+P L + SP+ LV+ S+P D+LTY
Sbjct: 3 TKLELMRSNYLKKLLTEIVPALAENSPEAALVVVSDPPVDDVLTY 47
>UniRef50_Q74ZH8 Cluster: AGR229Wp; n=2; Eremothecium gossypii|Rep:
AGR229Wp - Ashbya gossypii (Yeast) (Eremothecium
gossypii)
Length = 705
Score = 32.7 bits (71), Expect = 7.7
Identities = 16/44 (36%), Positives = 21/44 (47%)
Frame = +3
Query: 57 TEPQDGVPEEAVPARAREGGRNLEQGDHCRGRSGWDGRSFLYAD 188
T ++G E+ P R R RNL +G GWDG + L D
Sbjct: 120 TPEKEGAYEKMTPVRPRAEARNLRAELEQQGSEGWDGVAALLED 163
>UniRef50_Q4P6B5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 763
Score = 32.7 bits (71), Expect = 7.7
Identities = 17/60 (28%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +1
Query: 88 LFQPVHEKVDETWSKVTIVGVGQVGMAAAFSMLTQNVTNNIALVDMMADKL-KGEMMDLQ 264
L P + V E++ + I+G G G+ AA + Q + ++ ++D DK+ G+ LQ
Sbjct: 11 LSAPSGDSVKESYCDILIIGAGPAGLMAANWLAVQGLGPSVRIIDKRNDKIFNGQADGLQ 70
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 673,406,312
Number of Sequences: 1657284
Number of extensions: 14410438
Number of successful extensions: 50620
Number of sequences better than 10.0: 174
Number of HSP's better than 10.0 without gapping: 47870
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 50504
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 47711253245
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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