Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner10i17f
(641 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AB353947-1|BAF75364.1| 1257|Homo sapiens ATP-binding cassette, s... 70 6e-12
M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein. 68 2e-11
BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette, s... 68 2e-11
AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette, s... 68 2e-11
AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein. 68 2e-11
AC002457-1|AAM49149.1| 234|Homo sapiens unknown protein. 68 2e-11
M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein. 64 3e-10
M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane ... 60 9e-09
EF034088-1|ABJ53424.1| 1286|Homo sapiens ATP-binding cassette, s... 60 9e-09
BC042531-1|AAH42531.1| 1286|Homo sapiens ATP-binding cassette, s... 60 9e-09
AC006154-1|AAD05023.1| 407|Homo sapiens unknown protein. 58 4e-08
AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump p... 52 2e-06
AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump p... 52 2e-06
AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein. 52 2e-06
BC020618-1|AAH20618.1| 179|Homo sapiens ABCB4 protein protein. 48 4e-05
AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance pr... 40 0.008
DQ861346-1|ABH04421.1| 63|Homo sapiens variant ATP-binding cas... 36 0.092
BC064930-1|AAH64930.1| 738|Homo sapiens ATP-binding cassette, s... 36 0.12
AL121990-4|CAI22012.1| 738|Homo sapiens ATP-binding cassette, s... 36 0.12
AF216833-1|AAF78198.1| 738|Homo sapiens M-ABC2 protein protein. 36 0.12
AB013380-1|BAB20265.1| 737|Homo sapiens mono ATP-binding casset... 36 0.12
U63455-1|AAB36700.1| 1581|Homo sapiens sulfonylurea receptor pro... 31 2.6
U63421-1|AAB36699.1| 1581|Homo sapiens sulfonylurea receptor pro... 31 2.6
AF087138-1|AAC36724.1| 1581|Homo sapiens sulfonylurea receptor 1... 31 2.6
L78243-2|AAB02418.1| 1582|Homo sapiens SUR1 protein. 30 6.1
L78243-1|AAB02417.1| 1581|Homo sapiens SUR1 protein. 30 6.1
L78207-1|AAB02278.1| 1581|Homo sapiens sulfonylurea receptor pro... 30 6.1
>AB353947-1|BAF75364.1| 1257|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 5 protein.
Length = 1257
Score = 70.1 bits (164), Expect = 6e-12
Identities = 47/171 (27%), Positives = 88/171 (51%), Gaps = 1/171 (0%)
Frame = +1
Query: 118 VSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERTKYHDRLSSYL 297
V +IFR+ + L++ LG++ +++GA + L +GE+S + ++Y
Sbjct: 31 VGSIEIFRFADGLDITLMILGILASLVNGACLPLMPLVLGEMSDNLISGCLVQTNTTNYQ 90
Query: 298 PLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGV-SLVFCVLSFSLISWSALR 474
T Q+ E L +D + + ++ IGV +L+F + SL +A R
Sbjct: 91 NCT---------------QSQEKLNEDMTLLTL-YYVGIGVAALIFGYIQISLWIITAAR 134
Query: 475 QITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAVV 627
Q RIR F SVL QD+ W+D+ L ++M++++ I +G+G+K+A++
Sbjct: 135 QTKRIRKQFFHSVLAQDIGWFDSCDIGELNTRMTDDIDKISDGIGDKIALL 185
>M29447-1|AAA59576.1| 1280|Homo sapiens P glycoprotein protein.
Length = 1280
Score = 68.1 bits (159), Expect = 2e-11
Identities = 44/169 (26%), Positives = 84/169 (49%)
Frame = +1
Query: 118 VSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERTKYHDRLSSYL 297
VS F +FRY N L+ L +G + +I GAG+ +L GE++ F D +S+
Sbjct: 34 VSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNIT 93
Query: 298 PLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSALRQ 477
+ G +N E++M + G+ ++ + + F L+ A RQ
Sbjct: 94 NRSDINDTGF-FMNL--EEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLA-------AGRQ 143
Query: 478 ITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
I +IR F +++RQ++ W+D L +++++++ I EG+G+K+ +
Sbjct: 144 IHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGM 192
Score = 39.9 bits (89), Expect = 0.008
Identities = 17/51 (33%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +1
Query: 484 RIRTLFLRSVLRQDMSWYDTDSEFN--LASKMSENLMSIKEGMGEKLAVVS 630
R+R + RS+LRQD+SW+D L ++++ + +K +G +LAV++
Sbjct: 787 RLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 837
>BC130424-1|AAI30425.1| 1280|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 1 protein.
Length = 1280
Score = 68.1 bits (159), Expect = 2e-11
Identities = 44/169 (26%), Positives = 84/169 (49%)
Frame = +1
Query: 118 VSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERTKYHDRLSSYL 297
VS F +FRY N L+ L +G + +I GAG+ +L GE++ F D +S+
Sbjct: 34 VSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNIT 93
Query: 298 PLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSALRQ 477
+ G +N E++M + G+ ++ + + F L+ A RQ
Sbjct: 94 NRSDINDTGF-FMNL--EEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLA-------AGRQ 143
Query: 478 ITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
I +IR F +++RQ++ W+D L +++++++ I EG+G+K+ +
Sbjct: 144 IHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGM 192
Score = 39.9 bits (89), Expect = 0.008
Identities = 17/51 (33%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +1
Query: 484 RIRTLFLRSVLRQDMSWYDTDSEFN--LASKMSENLMSIKEGMGEKLAVVS 630
R+R + RS+LRQD+SW+D L ++++ + +K +G +LAV++
Sbjct: 787 RLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 837
>AY910577-1|AAW82430.1| 1280|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 1 protein.
Length = 1280
Score = 68.1 bits (159), Expect = 2e-11
Identities = 44/169 (26%), Positives = 84/169 (49%)
Frame = +1
Query: 118 VSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERTKYHDRLSSYL 297
VS F +FRY N L+ L +G + +I GAG+ +L GE++ F D +S+
Sbjct: 34 VSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNIT 93
Query: 298 PLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSALRQ 477
+ G +N E++M + G+ ++ + + F L+ A RQ
Sbjct: 94 NRSDINDTGF-FMNL--EEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLA-------AGRQ 143
Query: 478 ITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
I +IR F +++RQ++ W+D L +++++++ I EG+G+K+ +
Sbjct: 144 IHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGM 192
Score = 39.9 bits (89), Expect = 0.008
Identities = 17/51 (33%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +1
Query: 484 RIRTLFLRSVLRQDMSWYDTDSEFN--LASKMSENLMSIKEGMGEKLAVVS 630
R+R + RS+LRQD+SW+D L ++++ + +K +G +LAV++
Sbjct: 787 RLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 837
>AF016535-1|AAB69423.1| 1279|Homo sapiens P-glycoprotein protein.
Length = 1279
Score = 68.1 bits (159), Expect = 2e-11
Identities = 44/169 (26%), Positives = 84/169 (49%)
Frame = +1
Query: 118 VSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERTKYHDRLSSYL 297
VS F +FRY N L+ L +G + +I GAG+ +L GE++ F D +S+
Sbjct: 34 VSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNIT 93
Query: 298 PLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSALRQ 477
+ G +N E++M + G+ ++ + + F L+ A RQ
Sbjct: 94 NRSDINDTGF-FMNL--EEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLA-------AGRQ 143
Query: 478 ITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
I +IR F +++RQ++ W+D L +++++++ I EG+G+K+ +
Sbjct: 144 IHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGM 192
Score = 39.9 bits (89), Expect = 0.008
Identities = 17/51 (33%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +1
Query: 484 RIRTLFLRSVLRQDMSWYDTDSEFN--LASKMSENLMSIKEGMGEKLAVVS 630
R+R + RS+LRQD+SW+D L ++++ + +K +G +LAV++
Sbjct: 786 RLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 836
>AC002457-1|AAM49149.1| 234|Homo sapiens unknown protein.
Length = 234
Score = 68.1 bits (159), Expect = 2e-11
Identities = 44/169 (26%), Positives = 84/169 (49%)
Frame = +1
Query: 118 VSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERTKYHDRLSSYL 297
VS F +FRY N L+ L +G + +I GAG+ +L GE++ F D +S+
Sbjct: 34 VSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNIT 93
Query: 298 PLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSALRQ 477
+ G +N E++M + G+ ++ + + F L+ A RQ
Sbjct: 94 NRSDINDTGF-FMNL--EEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLA-------AGRQ 143
Query: 478 ITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
I +IR F +++RQ++ W+D L +++++++ I EG+G+K+ +
Sbjct: 144 IHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEGIGDKIGM 192
>M14758-1|AAA59575.1| 1280|Homo sapiens PGY1 protein.
Length = 1280
Score = 64.5 bits (150), Expect = 3e-10
Identities = 43/169 (25%), Positives = 83/169 (49%)
Frame = +1
Query: 118 VSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERTKYHDRLSSYL 297
VS F +FRY N L+ L +G + +I GAG+ +L GE++ F D +S+
Sbjct: 34 VSVFSMFRYSNWLDKLYMVVGTLAAIIHGAGLPLMMLVFGEMTDIFANAGNLEDLMSNIT 93
Query: 298 PLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSALRQ 477
+ G +N E++M + G+ ++ + + F L+ A RQ
Sbjct: 94 NRSDINDTGF-FMNL--EEDMTRYAYYYSGIGAGVLVAAYIQVSFWCLA-------AGRQ 143
Query: 478 ITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
I +IR F +++RQ++ W+D L +++++++ I E +G+K+ +
Sbjct: 144 IHKIRKQFFHAIMRQEIGWFDVHDVGELNTRLTDDVSKINEVIGDKIGM 192
Score = 39.9 bits (89), Expect = 0.008
Identities = 17/51 (33%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +1
Query: 484 RIRTLFLRSVLRQDMSWYDTDSEFN--LASKMSENLMSIKEGMGEKLAVVS 630
R+R + RS+LRQD+SW+D L ++++ + +K +G +LAV++
Sbjct: 787 RLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 837
>M23234-1|AAA36207.1| 1279|Homo sapiens protein ( Human membrane
glycoprotein P (mdr3) mRNA, complete cds. ).
Length = 1279
Score = 59.7 bits (138), Expect = 9e-09
Identities = 40/171 (23%), Positives = 84/171 (49%), Gaps = 1/171 (0%)
Frame = +1
Query: 115 LVSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERT-KYHDRLSS 291
++ +FRY + + L +LG + + G+G+ ++ GE++ FV+ + ++
Sbjct: 39 MIGVLTLFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDTAGNFSFPVNF 98
Query: 292 YLPLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSAL 471
L L GK L E+ M + G+ ++ + + F L +A
Sbjct: 99 SLSL---LNPGKIL-----EEEMTRYAYYYSGLGAGVLVAAYIQVSFWTL-------AAG 143
Query: 472 RQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
RQI +IR F ++LRQ++ W+D + L +++++++ I EG+G+K+ +
Sbjct: 144 RQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGM 194
Score = 36.7 bits (81), Expect = 0.070
Identities = 15/51 (29%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +1
Query: 484 RIRTLFLRSVLRQDMSWYD--TDSEFNLASKMSENLMSIKEGMGEKLAVVS 630
R+R++ +++LRQDMSW+D +S L+++++ + ++ G +LA+++
Sbjct: 786 RLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIA 836
>EF034088-1|ABJ53424.1| 1286|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 4 protein.
Length = 1286
Score = 59.7 bits (138), Expect = 9e-09
Identities = 40/171 (23%), Positives = 84/171 (49%), Gaps = 1/171 (0%)
Frame = +1
Query: 115 LVSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERT-KYHDRLSS 291
++ +FRY + + L +LG + + G+G+ ++ GE++ FV+ + ++
Sbjct: 39 MIGVLTLFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDTAGNFSFPVNF 98
Query: 292 YLPLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSAL 471
L L GK L E+ M + G+ ++ + + F L +A
Sbjct: 99 SLSL---LNPGKIL-----EEEMTRYAYYYSGLGAGVLVAAYIQVSFWTL-------AAG 143
Query: 472 RQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
RQI +IR F ++LRQ++ W+D + L +++++++ I EG+G+K+ +
Sbjct: 144 RQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGM 194
Score = 36.7 bits (81), Expect = 0.070
Identities = 15/51 (29%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +1
Query: 484 RIRTLFLRSVLRQDMSWYD--TDSEFNLASKMSENLMSIKEGMGEKLAVVS 630
R+R++ +++LRQDMSW+D +S L+++++ + ++ G +LA+++
Sbjct: 786 RLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIA 836
>BC042531-1|AAH42531.1| 1286|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 4 protein.
Length = 1286
Score = 59.7 bits (138), Expect = 9e-09
Identities = 40/171 (23%), Positives = 84/171 (49%), Gaps = 1/171 (0%)
Frame = +1
Query: 115 LVSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERT-KYHDRLSS 291
++ +FRY + + L +LG + + G+G+ ++ GE++ FV+ + ++
Sbjct: 39 MIGVLTLFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDTAGNFSFPVNF 98
Query: 292 YLPLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSAL 471
L L GK L E+ M + G+ ++ + + F L +A
Sbjct: 99 SLSL---LNPGKIL-----EEEMTRYAYYYSGLGAGVLVAAYIQVSFWTL-------AAG 143
Query: 472 RQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
RQI +IR F ++LRQ++ W+D + L +++++++ I EG+G+K+ +
Sbjct: 144 RQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGM 194
Score = 36.7 bits (81), Expect = 0.070
Identities = 15/51 (29%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +1
Query: 484 RIRTLFLRSVLRQDMSWYD--TDSEFNLASKMSENLMSIKEGMGEKLAVVS 630
R+R++ +++LRQDMSW+D +S L+++++ + ++ G +LA+++
Sbjct: 786 RLRSMAFKAMLRQDMSWFDDHKNSTGALSTRLATDAAQVQGATGTRLALIA 836
>AC006154-1|AAD05023.1| 407|Homo sapiens unknown protein.
Length = 407
Score = 57.6 bits (133), Expect = 4e-08
Identities = 40/164 (24%), Positives = 81/164 (49%), Gaps = 1/164 (0%)
Frame = +1
Query: 136 FRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERT-KYHDRLSSYLPLTAT 312
FRY + + L +LG + + G+G+ ++ GE++ FV+ + ++ L L
Sbjct: 1 FRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDTAGNFSFPVNFSLSL--- 57
Query: 313 FGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSALRQITRIR 492
GK L E+ M + G+ ++ + + F L +A RQI +IR
Sbjct: 58 LNPGKIL-----EEEMTRYAYYYSGLGAGVLVAAYIQVSFWTL-------AAGRQIRKIR 105
Query: 493 TLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
F ++LRQ++ W+D + L +++++++ I EG+G+K+ +
Sbjct: 106 QKFFHAILRQEIGWFDINDTTELNTRLTDDISKISEGIGDKVGM 149
>AF136523-1|AAD28285.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 52.0 bits (119), Expect = 2e-06
Identities = 38/177 (21%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Frame = +1
Query: 118 VSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERTKYHDRLSSYL 297
V FFQ+FR+ + ++ +G + + G LL G ++ F++ L +
Sbjct: 45 VGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQ--I 102
Query: 298 PLTATFGGGKRLVNATHEQNME-----ALIDDAKAMAIGMFISIGVSLVFCVLSFSLIS- 459
P A N++ QNM L++ M G+++ + + I
Sbjct: 103 PGKACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICF 162
Query: 460 W--SALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
W +A RQI ++R + R ++R ++ W+D +S L ++ S+++ I + + +++A+
Sbjct: 163 WVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMAL 219
Score = 30.3 bits (65), Expect = 6.1
Identities = 19/81 (23%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Frame = +1
Query: 400 MFISIG-VSLVFCVLSFSLISWSALRQITRIRTLFLRSVLRQDMSWYD--TDSEFNLASK 570
+F+++G VSL L + S R+R R++L QD++W+D +S L ++
Sbjct: 801 LFVAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTR 860
Query: 571 MSENLMSIKEGMGEKLAVVSN 633
++ + ++ G ++ ++ N
Sbjct: 861 LATDASQVQGAAGSQIGMIVN 881
>AF091582-1|AAC77455.1| 1321|Homo sapiens bile salt export pump
protein.
Length = 1321
Score = 52.0 bits (119), Expect = 2e-06
Identities = 38/177 (21%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Frame = +1
Query: 118 VSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERTKYHDRLSSYL 297
V FFQ+FR+ + ++ +G + + G LL G ++ F++ L +
Sbjct: 45 VGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQ--I 102
Query: 298 PLTATFGGGKRLVNATHEQNME-----ALIDDAKAMAIGMFISIGVSLVFCVLSFSLIS- 459
P A N++ QNM L++ M G+++ + + I
Sbjct: 103 PGKACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICF 162
Query: 460 W--SALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
W +A RQI ++R + R ++R ++ W+D +S L ++ S+++ I + + +++A+
Sbjct: 163 WVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMAL 219
Score = 30.3 bits (65), Expect = 6.1
Identities = 19/81 (23%), Positives = 42/81 (51%), Gaps = 3/81 (3%)
Frame = +1
Query: 400 MFISIG-VSLVFCVLSFSLISWSALRQITRIRTLFLRSVLRQDMSWYD--TDSEFNLASK 570
+F+++G VSL L + S R+R R++L QD++W+D +S L ++
Sbjct: 801 LFVAMGCVSLFTQFLQGYAFAKSGELLTKRLRKFGFRAMLGQDIAWFDDLRNSPGALTTR 860
Query: 571 MSENLMSIKEGMGEKLAVVSN 633
++ + ++ G ++ ++ N
Sbjct: 861 LATDASQVQGAAGSQIGMIVN 881
>AC008177-1|AAY24305.1| 870|Homo sapiens unknown protein.
Length = 870
Score = 52.0 bits (119), Expect = 2e-06
Identities = 38/177 (21%), Positives = 81/177 (45%), Gaps = 8/177 (4%)
Frame = +1
Query: 118 VSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERTKYHDRLSSYL 297
V FFQ+FR+ + ++ +G + + G LL G ++ F++ L +
Sbjct: 45 VGFFQLFRFSSSTDIWLMFVGSLCAFLHGIAQPGVLLIFGTMTDVFIDYDVELQELQ--I 102
Query: 298 PLTATFGGGKRLVNATHEQNME-----ALIDDAKAMAIGMFISIGVSLVFCVLSFSLIS- 459
P A N++ QNM L++ M G+++ + + I
Sbjct: 103 PGKACVNNTIVWTNSSLNQNMTNGTRCGLLNIESEMIKFASYYAGIAVAVLITGYIQICF 162
Query: 460 W--SALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLAV 624
W +A RQI ++R + R ++R ++ W+D +S L ++ S+++ I + + +++A+
Sbjct: 163 WVIAAARQIQKMRKFYFRRIMRMEIGWFDCNSVGELNTRFSDDINKINDAIADQMAL 219
>BC020618-1|AAH20618.1| 179|Homo sapiens ABCB4 protein protein.
Length = 179
Score = 47.6 bits (108), Expect = 4e-05
Identities = 36/156 (23%), Positives = 73/156 (46%), Gaps = 1/156 (0%)
Frame = +1
Query: 115 LVSFFQIFRYGNCLELLATALGVVFGMISGAGVCCNLLQIGELSTAFVERT-KYHDRLSS 291
++ +FRY + + L +LG + + G+G+ ++ GE++ FV+ + ++
Sbjct: 39 MIGVLTLFRYSDWQDKLFMSLGTIMAIAHGSGLPLMMIVFGEMTDKFVDTAGNFSFPVNF 98
Query: 292 YLPLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISWSAL 471
L L GK L E+ M + G+ ++ + + F L +A
Sbjct: 99 SLSL---LNPGKIL-----EEEMTRYAYYYSGLGAGVLVAAYIQVSFWTL-------AAG 143
Query: 472 RQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSE 579
RQI +IR F ++LRQ++ W+D + L ++++E
Sbjct: 144 RQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLTE 179
>AB208970-1|BAD92207.1| 1062|Homo sapiens Multidrug resistance
protein 1 variant protein.
Length = 1062
Score = 39.9 bits (89), Expect = 0.008
Identities = 17/51 (33%), Positives = 32/51 (62%), Gaps = 2/51 (3%)
Frame = +1
Query: 484 RIRTLFLRSVLRQDMSWYDTDSEFN--LASKMSENLMSIKEGMGEKLAVVS 630
R+R + RS+LRQD+SW+D L ++++ + +K +G +LAV++
Sbjct: 569 RLRYMVFRSMLRQDVSWFDDPKNTTGALTTRLANDAAQVKGAIGSRLAVIT 619
>DQ861346-1|ABH04421.1| 63|Homo sapiens variant ATP-binding
cassette sub-family B member 4 protein.
Length = 63
Score = 36.3 bits (80), Expect = 0.092
Identities = 16/51 (31%), Positives = 30/51 (58%)
Frame = +1
Query: 424 LVFCVLSFSLISWSALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMS 576
LV + S + +A RQI +IR F ++LRQ++ W+D + L ++++
Sbjct: 13 LVAAYIQVSFWTLAAGRQIRKIRQKFFHAILRQEIGWFDINDTTELNTRLT 63
>BC064930-1|AAH64930.1| 738|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 10 protein.
Length = 738
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/113 (20%), Positives = 52/113 (46%)
Frame = +1
Query: 283 LSSYLPLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISW 462
+SS + ++A F GK +++ + D+ + +G+ + L+
Sbjct: 180 MSSVISMSAPFFLGK-IIDVIYTNPTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQT 238
Query: 463 SALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLA 621
S R + R+RT S+LRQ+++++D L +++S + + + E L+
Sbjct: 239 SGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLS 291
>AL121990-4|CAI22012.1| 738|Homo sapiens ATP-binding cassette,
sub-family B (MDR/TAP), member 10 protein.
Length = 738
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/113 (20%), Positives = 52/113 (46%)
Frame = +1
Query: 283 LSSYLPLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISW 462
+SS + ++A F GK +++ + D+ + +G+ + L+
Sbjct: 180 MSSVISMSAPFFLGK-IIDVIYTNPTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQT 238
Query: 463 SALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLA 621
S R + R+RT S+LRQ+++++D L +++S + + + E L+
Sbjct: 239 SGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLS 291
>AF216833-1|AAF78198.1| 738|Homo sapiens M-ABC2 protein protein.
Length = 738
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/113 (20%), Positives = 52/113 (46%)
Frame = +1
Query: 283 LSSYLPLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISW 462
+SS + ++A F GK +++ + D+ + +G+ + L+
Sbjct: 180 MSSVISMSAPFFLGK-IIDVIYTNPTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQT 238
Query: 463 SALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLA 621
S R + R+RT S+LRQ+++++D L +++S + + + E L+
Sbjct: 239 SGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLS 291
>AB013380-1|BAB20265.1| 737|Homo sapiens mono ATP-binding cassette
protein protein.
Length = 737
Score = 35.9 bits (79), Expect = 0.12
Identities = 23/113 (20%), Positives = 52/113 (46%)
Frame = +1
Query: 283 LSSYLPLTATFGGGKRLVNATHEQNMEALIDDAKAMAIGMFISIGVSLVFCVLSFSLISW 462
+SS + ++A F GK +++ + D+ + +G+ + L+
Sbjct: 180 MSSVISMSAPFFLGK-IIDVIYTNPTVDYSDNLTRLCLGLSAVFLCGAAANAIRVYLMQT 238
Query: 463 SALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLASKMSENLMSIKEGMGEKLA 621
S R + R+RT S+LRQ+++++D L +++S + + + E L+
Sbjct: 239 SGQRIVNRLRTSLFSSILRQEVAFFDKTRTGELINRLSSDTALLGRSVTENLS 291
>U63455-1|AAB36700.1| 1581|Homo sapiens sulfonylurea receptor protein.
Length = 1581
Score = 31.5 bits (68), Expect = 2.6
Identities = 16/82 (19%), Positives = 40/82 (48%)
Frame = +1
Query: 385 AMAIGMFISIGVSLVFCVLSFSLISWSALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLA 564
AM + S+G+ V C+++ + W+ L+ R+ L ++ M +++T ++
Sbjct: 1064 AMVFTVLCSLGI--VLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSIL 1121
Query: 565 SKMSENLMSIKEGMGEKLAVVS 630
++ S + +I + + L +S
Sbjct: 1122 NRFSSDCNTIDQHIPSTLECLS 1143
>U63421-1|AAB36699.1| 1581|Homo sapiens sulfonylurea receptor protein.
Length = 1581
Score = 31.5 bits (68), Expect = 2.6
Identities = 16/82 (19%), Positives = 40/82 (48%)
Frame = +1
Query: 385 AMAIGMFISIGVSLVFCVLSFSLISWSALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLA 564
AM + S+G+ V C+++ + W+ L+ R+ L ++ M +++T ++
Sbjct: 1064 AMVFTVLCSLGI--VLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSIL 1121
Query: 565 SKMSENLMSIKEGMGEKLAVVS 630
++ S + +I + + L +S
Sbjct: 1122 NRFSSDCNTIDQHIPSTLECLS 1143
>AF087138-1|AAC36724.1| 1581|Homo sapiens sulfonylurea receptor 1
protein.
Length = 1581
Score = 31.5 bits (68), Expect = 2.6
Identities = 16/82 (19%), Positives = 40/82 (48%)
Frame = +1
Query: 385 AMAIGMFISIGVSLVFCVLSFSLISWSALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLA 564
AM + S+G+ V C+++ + W+ L+ R+ L ++ M +++T ++
Sbjct: 1064 AMVFTVLCSLGI--VLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSIL 1121
Query: 565 SKMSENLMSIKEGMGEKLAVVS 630
++ S + +I + + L +S
Sbjct: 1122 NRFSSDCNTIDQHIPSTLECLS 1143
>L78243-2|AAB02418.1| 1582|Homo sapiens SUR1 protein.
Length = 1582
Score = 30.3 bits (65), Expect = 6.1
Identities = 16/82 (19%), Positives = 39/82 (47%)
Frame = +1
Query: 385 AMAIGMFISIGVSLVFCVLSFSLISWSALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLA 564
AM S+G+ V C+++ + W+ L+ R+ L ++ M +++T ++
Sbjct: 1065 AMVFTAVCSLGI--VLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSIL 1122
Query: 565 SKMSENLMSIKEGMGEKLAVVS 630
++ S + +I + + L +S
Sbjct: 1123 NRFSSDCNTIDQHIPSTLECLS 1144
>L78243-1|AAB02417.1| 1581|Homo sapiens SUR1 protein.
Length = 1581
Score = 30.3 bits (65), Expect = 6.1
Identities = 16/82 (19%), Positives = 39/82 (47%)
Frame = +1
Query: 385 AMAIGMFISIGVSLVFCVLSFSLISWSALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLA 564
AM S+G+ V C+++ + W+ L+ R+ L ++ M +++T ++
Sbjct: 1064 AMVFTAVCSLGI--VLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSIL 1121
Query: 565 SKMSENLMSIKEGMGEKLAVVS 630
++ S + +I + + L +S
Sbjct: 1122 NRFSSDCNTIDQHIPSTLECLS 1143
>L78207-1|AAB02278.1| 1581|Homo sapiens sulfonylurea receptor protein.
Length = 1581
Score = 30.3 bits (65), Expect = 6.1
Identities = 16/82 (19%), Positives = 39/82 (47%)
Frame = +1
Query: 385 AMAIGMFISIGVSLVFCVLSFSLISWSALRQITRIRTLFLRSVLRQDMSWYDTDSEFNLA 564
AM S+G+ V C+++ + W+ L+ R+ L ++ M +++T ++
Sbjct: 1064 AMVFTAVCSLGI--VLCLVTSVTVEWTGLKVAKRLHRSLLNRIILAPMRFFETTPLGSIL 1121
Query: 565 SKMSENLMSIKEGMGEKLAVVS 630
++ S + +I + + L +S
Sbjct: 1122 NRFSSDCNTIDQHIPSTLECLS 1143
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,567,707
Number of Sequences: 237096
Number of extensions: 1899441
Number of successful extensions: 4235
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 4107
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4226
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7085195460
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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