Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner10h12r
(742 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p - ... 315 8e-85
UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase doma... 279 4e-74
UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome s... 276 4e-73
UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3; ... 266 5e-70
UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura... 250 2e-65
UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1; Dictyo... 250 4e-65
UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 224 2e-57
UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 206 3e-52
UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 206 4e-52
UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 compone... 205 8e-52
UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; ... 202 9e-51
UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1; Bdello... 200 2e-50
UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 200 3e-50
UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome s... 198 9e-50
UniRef50_Q50992 Cluster: SucA protein; n=3; Neisseria|Rep: SucA ... 198 2e-49
UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 198 2e-49
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 196 4e-49
UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 196 5e-49
UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17; Bacte... 196 6e-49
UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 195 8e-49
UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;... 195 8e-49
UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 194 2e-48
UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr... 194 3e-48
UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E... 193 3e-48
UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 193 4e-48
UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 193 4e-48
UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 192 8e-48
UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 190 3e-47
UniRef50_UPI0000DAE34D Cluster: hypothetical protein Rgryl_01000... 189 5e-47
UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 189 5e-47
UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1... 189 7e-47
UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 188 9e-47
UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein;... 188 1e-46
UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridipla... 187 2e-46
UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, who... 186 4e-46
UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E... 186 7e-46
UniRef50_Q4AFR5 Cluster: Oxoglutarate dehydrogenase; n=1; Chloro... 185 1e-45
UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 185 1e-45
UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 184 2e-45
UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 184 2e-45
UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 183 4e-45
UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 183 5e-45
UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 182 6e-45
UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 182 6e-45
UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 182 6e-45
UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole gen... 182 1e-44
UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albica... 181 2e-44
UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 180 3e-44
UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 179 8e-44
UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC... 178 1e-43
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 177 2e-43
UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 177 3e-43
UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 177 3e-43
UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 176 5e-43
UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 175 7e-43
UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 174 2e-42
UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ... 171 2e-41
UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 171 2e-41
UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative;... 171 2e-41
UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 171 2e-41
UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 171 2e-41
UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus lu... 167 3e-40
UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 167 3e-40
UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 164 2e-39
UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 161 2e-38
UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 153 3e-36
UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, p... 153 6e-36
UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, wh... 150 3e-35
UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 compone... 150 4e-35
UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 149 5e-35
UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 144 3e-33
UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 141 1e-32
UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 139 6e-32
UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase,... 139 8e-32
UniRef50_Q3KTJ4 Cluster: SJCHGC05401 protein; n=1; Schistosoma j... 44 0.004
UniRef50_Q7NGX0 Cluster: Gll2767 protein; n=17; Bacteria|Rep: Gl... 34 4.2
UniRef50_Q9FG37 Cluster: Gamma-tubulin interacting protein-like;... 33 5.6
UniRef50_A7P438 Cluster: Chromosome chr1 scaffold_5, whole genom... 33 5.6
UniRef50_Q6F0F8 Cluster: Zinc metalloprotease; n=3; Mollicutes|R... 33 9.7
>UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p -
Drosophila melanogaster (Fruit fly)
Length = 919
Score = 315 bits (773), Expect = 8e-85
Identities = 141/236 (59%), Positives = 180/236 (76%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I SGE+KW+ SN LVMLLPHGYDGAASEHSSCR+ERFLQL DS E++ D ++ +H+ NP
Sbjct: 681 IVSGETKWMESNALVMLLPHGYDGAASEHSSCRIERFLQLCDSKETSADGDSVNVHIVNP 740
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPAQY+H+LRRQ+ RN+RKPL++VAPK LLRL A S DF P T F V+GD +A
Sbjct: 741 TTPAQYYHVLRRQLARNFRKPLVVVAPKTLLRLPAATSTHEDFQPGTLFHNVLGDTIAKP 800
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
+V++VI SGKHYY L +ER + + D AI+R+E+L PFP+ ELQ QL++Y N F+W
Sbjct: 801 EQVRKVILCSGKHYYTLAEEREKRQAYDTAILRLESLCPFPIQELQAQLAQYGNVQSFVW 860
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKEP 11
SQEEHRNMGAW+F++PRFENL G++L Y GR EAPTPA G +H+ EV+ + P
Sbjct: 861 SQEEHRNMGAWTFVRPRFENLIGQQLHYCGRCEAPTPATGIGKVHKREVDEIDAAP 916
>UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase
domain-containing protein 1; n=39; Eumetazoa|Rep:
Dehydrogenase E1 and transketolase domain-containing
protein 1 - Homo sapiens (Human)
Length = 919
Score = 279 bits (685), Expect = 4e-74
Identities = 131/235 (55%), Positives = 165/235 (70%), Gaps = 2/235 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+ GE+KW+ +G+V+LLPHGYDGA +HSSCR+ERFLQ+ DS E D + + V +P
Sbjct: 680 ISGGEAKWLLQSGIVILLPHGYDGAGPDHSSCRIERFLQMCDSAEEGVDGDTVNMFVVHP 739
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPAQYFHLLRRQ+VRN+RKPLI+ +PK+LLRL AVS L + AP T F PVIGD D
Sbjct: 740 TTPAQYFHLLRRQMVRNFRKPLIVASPKMLLRLPAAVSTLQEMAPGTTFNPVIGDSSVDP 799
Query: 358 LKVKRVIFVSGKHYYELHKER--VRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKF 185
KVK ++F SGKH+Y L K+R + A+ D AI+RVE L PFPL LQ ++SKYK+
Sbjct: 800 KKVKTLVFCSGKHFYSLVKQRESLGAKKHDFAIIRVEELCPFPLDSLQQEMSKYKHVKDH 859
Query: 184 IWSQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVL 20
IWSQEE +NMG WSF+ PRFE KL GR P PAVG ++H + E +L
Sbjct: 860 IWSQEEPQNMGPWSFVSPRFEKQLACKLRLVGRPPLPVPAVGIGTVHLHQHEDIL 914
>UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF15000, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 974
Score = 276 bits (677), Expect = 4e-73
Identities = 127/235 (54%), Positives = 165/235 (70%), Gaps = 1/235 (0%)
Frame = -1
Query: 721 VIASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVAN 542
++++GE+KW+ NG+V+LLPHGYDGA EHSSC +ERFLQ+ DS E D + + V N
Sbjct: 735 LVSAGEAKWLLQNGMVILLPHGYDGAGPEHSSCHMERFLQMCDSKEEGVDGDNVNMAVVN 794
Query: 541 PTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLAD 362
PTTPAQYFHLLRRQ++RN+RKPLI+V PK LLR + AVS L++ AP T F+PV+GD
Sbjct: 795 PTTPAQYFHLLRRQMIRNFRKPLIVVGPKTLLRFSGAVSSLAEMAPGTSFRPVLGDASLS 854
Query: 361 ALKVKRVIFVSGKHYYELHKER-VRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKF 185
V+RV+ SGKHYY L K+R A ++ A+VR+E L PFPL LQ +L KY AT+F
Sbjct: 855 GDSVQRVVLCSGKHYYTLLKQRETSAAKQNTALVRLEELCPFPLEALQQELKKYPRATEF 914
Query: 184 IWSQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVL 20
+WSQEE +NMG W+F+ PRFE KL R P PAVG +LH+ + E +L
Sbjct: 915 VWSQEEPQNMGPWTFVAPRFEKQLACKLRLVSRPALPAPAVGIGTLHQQQQEAIL 969
>UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3;
Bilateria|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 911
Score = 266 bits (651), Expect = 5e-70
Identities = 135/239 (56%), Positives = 163/239 (68%), Gaps = 4/239 (1%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAP--DSEAACLHVA 545
+AS ESKW+ S+GL MLLPHG+DGA EHSSCR+ERFLQL DS E D E + VA
Sbjct: 670 LASAESKWLTSSGLTMLLPHGFDGAGPEHSSCRMERFLQLCDSREDQTPVDGENVNMRVA 729
Query: 544 NPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLA 365
NPTT AQYFHLLRRQVV NYRKPLI+V PK+LLR A S +++F P T +Q VI + A
Sbjct: 730 NPTTSAQYFHLLRRQVVPNYRKPLIVVGPKILLRHPKAASTINEFGPGTTYQNVISEEHA 789
Query: 364 -DALKVKRVIFVSGKHYYELHKERVRARLED-VAIVRVEALAPFPLPELQMQLSKYKNAT 191
+ K+K+VIFVSGKH+ + K R L+D VAIVRVE L PFP+ +LQ L KY A
Sbjct: 790 TSSQKIKKVIFVSGKHWINVEKARDERGLKDSVAIVRVEMLCPFPVVDLQAVLKKYPGAQ 849
Query: 190 KFIWSQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKE 14
F+WSQEE RN GAWSF++PRFEN G +L +AGR E A H E E V+ +
Sbjct: 850 DFVWSQEEPRNAGAWSFVRPRFENALGVRLKFAGRPELAWTATAIGEHHTKEAEEVINQ 908
>UniRef50_Q675U8 Cluster: CG1544-PA-like protein; n=1; Oikopleura
dioica|Rep: CG1544-PA-like protein - Oikopleura dioica
(Tunicate)
Length = 886
Score = 250 bits (613), Expect = 2e-65
Identities = 121/237 (51%), Positives = 160/237 (67%), Gaps = 1/237 (0%)
Frame = -1
Query: 721 VIASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVAN 542
++ GE KW + L+MLLPHGYDGA EHSS R+ER LQ+TDS E+ DS+ +
Sbjct: 647 LVTCGEQKWGLQSSLLMLLPHGYDGAGPEHSSSRVERLLQMTDSLENGVDSDNINFQILW 706
Query: 541 PTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLAD 362
P+T AQYFH+LRRQ+VRNYRKP IV PK LLRL ++ S ++ P T FQ VI D +
Sbjct: 707 PSTAAQYFHILRRQMVRNYRKPGAIVMPKTLLRLPESRSTFAEMGPNTSFQTVIDDP-SK 765
Query: 361 ALKVKRVIFVSGKHYYELHKERVRARLE-DVAIVRVEALAPFPLPELQMQLSKYKNATKF 185
+K KRV+ +GKHY+ L ER + ++ DVAIVR+E L PFP E+Q L++Y NAT F
Sbjct: 766 NMKAKRVVVTAGKHYFTLVNERAKRGMQNDVAIVRLEQLVPFPAKEIQETLARYTNATSF 825
Query: 184 IWSQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKE 14
++SQEE RN GAWSF KPR + + GR+ Y GR E PT A G +HR ++ +L++
Sbjct: 826 VFSQEEPRNCGAWSFAKPRLDFISGRRFSYTGRPEMPTSATGTGVMHRRQLADLLED 882
>UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1;
Dictyostelium discoideum AX4|Rep: Oxoglutarate
dehydrogenase - Dictyostelium discoideum AX4
Length = 900
Score = 250 bits (611), Expect = 4e-65
Identities = 119/242 (49%), Positives = 166/242 (68%), Gaps = 9/242 (3%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPE-SAPD----SEAACL 554
+ SGESKW+R +G+V+LLPHG+DGA EHSSCR+ERFLQL+D+ + D ++
Sbjct: 653 VTSGESKWLRQSGIVILLPHGFDGAGPEHSSCRIERFLQLSDTEAVNVKDDTLINQETNF 712
Query: 553 HVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGD 374
+ NP+TPA YFH LRRQ++RNYRKPLI+ PK+LLR + S L++ AP THFQ V+ D
Sbjct: 713 YFINPSTPANYFHALRRQMIRNYRKPLIVAGPKVLLRHPNCFSTLNEMAPGTHFQTVLSD 772
Query: 373 G--LADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYK 200
+ +A +KRVIF SGK +Y+L +ER DVAI+R+E +APFP +Q ++++Y
Sbjct: 773 PDTINNASTIKRVIFCSGKVFYDLQEERKAKNFNDVAIIRLEQIAPFPYQRIQEEINRYS 832
Query: 199 NATKFIWSQEEHRNMGAWSFMKPRFENLCGR--KLVYAGRSEAPTPAVGASSLHRVEVEH 26
NATKF W QEE +N G WSF++PRF+ + ++ Y GR A+G SS+H+ EV
Sbjct: 833 NATKFAWVQEEQQNGGCWSFVEPRFKQRYPQTSQIKYIGRPPLAASAIGISSIHKKEVSQ 892
Query: 25 VL 20
+L
Sbjct: 893 LL 894
>UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=4; Leptospira|Rep: 2-oxoglutarate dehydrogenase E1
component - Leptospira interrogans
Length = 920
Score = 224 bits (547), Expect = 2e-57
Identities = 114/235 (48%), Positives = 154/235 (65%), Gaps = 2/235 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+S E KW R +GL+MLLPHGY+G EHSS RLERFLQL A D+ C N
Sbjct: 689 ISSSEVKWQRLSGLIMLLPHGYEGQGPEHSSARLERFLQLC-----ALDNMQVC----NL 739
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TT AQYFHLLRRQ++RNYRKPL+IV PK LLR ++SP+ D + +I D +
Sbjct: 740 TTAAQYFHLLRRQMLRNYRKPLVIVTPKSLLRFPASLSPVEDILQGAFREILIDDSGSKP 799
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
K+++V+F +GK YY+L K + ++++VA+VRVE + PFP E+Q L +KNA +F+W
Sbjct: 800 DKIEKVVFSAGKVYYDLMKYKDENKIKNVALVRVEQIYPFPAKEIQSSLKTFKNAKQFVW 859
Query: 178 SQEEHRNMGAWSFMKPRFENLC--GRKLVYAGRSEAPTPAVGASSLHRVEVEHVL 20
QEE +N GAW F++ R E L +LVYAGR E+P+PA G LH E + ++
Sbjct: 860 CQEEPKNQGAWFFVRERIEELLPGNARLVYAGRHESPSPAAGHMKLHLQEQDQLV 914
>UniRef50_Q74B13 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=8; Deltaproteobacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Geobacter sulfurreducens
Length = 894
Score = 206 bits (504), Expect = 3e-52
Identities = 115/237 (48%), Positives = 149/237 (62%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
IA GESKW R +GLVMLLPHGY+G +EHSS R+ER+LQL A D+ L VA P
Sbjct: 667 IAGGESKWERVSGLVMLLPHGYEGQGAEHSSARIERYLQLC-----ADDN----LQVAYP 717
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
+TPAQ FHLLRRQV + +RKPL++ PK LLR VS L + + F+ VI +AD
Sbjct: 718 STPAQLFHLLRRQVKQPFRKPLVVFTPKSLLRHPRCVSRLEELSGGW-FREVIPP-VADP 775
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
K++R++ SGK YYEL + R + D AIVR+E L P L+ ++ ++ A W
Sbjct: 776 EKIRRLLLCSGKIYYELLERMERDAVADTAIVRIEQLYPLRTDLLREAVAPFRGAGSIAW 835
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKEPL 8
QEE RNMGAWSF++P +L GR+ Y GR + PAVG+ LH VE E V+ E L
Sbjct: 836 VQEEPRNMGAWSFLRPHLADLFGREPRYVGRPDNDVPAVGSHRLHGVEQERVVTEAL 892
>UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=12; root|Rep: 2-oxoglutarate dehydrogenase, E1
component - Polaromonas sp. (strain JS666 / ATCC BAA-500)
Length = 963
Score = 206 bits (503), Expect = 4e-52
Identities = 111/232 (47%), Positives = 147/232 (63%), Gaps = 6/232 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
IASGE KW R NG+ ++LPHGY+G EHSS RLERF+QL+ + V P
Sbjct: 721 IASGEVKWGRVNGITLMLPHGYEGQGPEHSSARLERFMQLSADTN---------MQVVQP 771
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TT +Q FH+LRRQ+VRN RKPL+I+ PK LLR DA SPLS+F + FQ +I + +
Sbjct: 772 TTASQIFHVLRRQMVRNLRKPLVIMTPKSLLRNKDATSPLSEFT-KGSFQTIIPENKEEI 830
Query: 358 LK----VKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNAT 191
+K VKR+I SGK YY+L K+R +DV I+RVE L PFP +L KY N T
Sbjct: 831 IKKADKVKRIIACSGKVYYDLAKKREEKGADDVVILRVEQLYPFPHKAFAAELKKYPNVT 890
Query: 190 KFIWSQEEHRNMGAWSFMKPRF-ENLC-GRKLVYAGRSEAPTPAVGASSLHR 41
+W Q+E +N GAW F++ EN+ G+KL Y+GR+ + +PA G S LH+
Sbjct: 891 DLVWCQDEPQNQGAWFFVQHYIHENMFEGQKLGYSGRAASASPASGYSYLHQ 942
>UniRef50_Q5FSJ1 Cluster: 2-Oxoglutarate dehydrogenase E1 component;
n=1; Gluconobacter oxydans|Rep: 2-Oxoglutarate
dehydrogenase E1 component - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 885
Score = 205 bits (501), Expect = 8e-52
Identities = 109/243 (44%), Positives = 144/243 (59%), Gaps = 6/243 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
IASGE+KW+R++GL +LLPHGY+G EHSS R ER LQL + V +
Sbjct: 652 IASGETKWLRTSGLTLLLPHGYEGGGPEHSSARPERILQLCAENN---------MRVCDI 702
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPA YFH LRRQ+ R RKPL++ PK LLR DAVS L + P T FQPVI D +
Sbjct: 703 TTPANYFHALRRQIARRCRKPLVVFTPKSLLRNKDAVSMLDEMGPHTRFQPVIADPAKED 762
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
+R+I +GK YY+L ER R +DVAI+RVE L PFP L QL+++ A + +W
Sbjct: 763 -GARRIILCTGKVYYDLAAERTRQNRDDVAIIRVEQLYPFPHHALMEQLARHPEAEQVLW 821
Query: 178 SQEEHRNMGAWSFMKPRFENL---CGRKLV---YAGRSEAPTPAVGASSLHRVEVEHVLK 17
QEE +N GAW F+ R E C ++ Y GR A +PA G +H + E +++
Sbjct: 822 CQEEPQNNGAWIFVDRRIERALRGCNHRVQRPDYVGRESAASPATGLPGVHAAQQEKLVQ 881
Query: 16 EPL 8
+ L
Sbjct: 882 DAL 884
>UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1013
Score = 202 bits (492), Expect = 9e-51
Identities = 112/254 (44%), Positives = 149/254 (58%), Gaps = 17/254 (6%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDS-PESAPDSEAA------ 560
I+SGE KW+R +GL MLLPHGYDGA EHSSCR+ER+LQL DS P P E A
Sbjct: 754 ISSGEQKWMRQSGLTMLLPHGYDGAGPEHSSCRIERYLQLCDSDPNKIPPKEEAERKQSQ 813
Query: 559 -C-LHVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFA--PRTHF 392
C + V N +TP YFH LRRQV R++RKPL+I PK LLR + S +F+ T
Sbjct: 814 HCNMQVLNCSTPVNYFHALRRQVHRDFRKPLVIATPKYLLRYEKSFSTAKEFSNDSFTRL 873
Query: 391 QP-VIGDGLADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQ 215
P D + K+ R++F +G+ YY L R ++DVAI+RVE L PFP + Q
Sbjct: 874 YPEAFPDQINKPEKINRIVFCTGQVYYNLIASRESNNIKDVAIIRVEQLHPFPFDLVAEQ 933
Query: 214 LSKYKNATKFIWSQEEHRNMGAWSFMKPRFENLCGR-----KLVYAGRSEAPTPAVGASS 50
L Y NA K IW QEE NMG W+++ P F + + Y GR + +PAV + +
Sbjct: 934 LQHYPNA-KAIWCQEEPMNMGYWNYIYPYFISTFKHINRPADITYTGRPSSASPAVASHT 992
Query: 49 LHRVEVEHVLKEPL 8
LH++++E+ L L
Sbjct: 993 LHKLQLENFLSNAL 1006
>UniRef50_Q6MJP2 Cluster: Oxoglutarate dehydrogenase; n=1;
Bdellovibrio bacteriovorus|Rep: Oxoglutarate
dehydrogenase - Bdellovibrio bacteriovorus
Length = 901
Score = 200 bits (489), Expect = 2e-50
Identities = 111/239 (46%), Positives = 150/239 (62%), Gaps = 5/239 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+A+GESKW + +GLV+LLPHGY+G EHSS RLERFLQL + V N
Sbjct: 669 LAAGESKWQQMSGLVLLLPHGYEGQGPEHSSARLERFLQLCAQNN---------MQVVNL 719
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPAQ +H LRRQV R++RKPL++++PK LLR AVS + D A + FQ VI D + D
Sbjct: 720 TTPAQIYHALRRQVCRDFRKPLVVMSPKSLLRHPRAVSSIEDLA-KGRFQEVIADTI-DK 777
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
KV V+FVSGK YYEL +ER +++ E+VA+VR+E + PFP ++ L Y A +W
Sbjct: 778 SKVDTVVFVSGKLYYELLEEREKSKKENVALVRLEQIYPFPATQVTEVLKSYPKAKTLVW 837
Query: 178 SQEEHRNMGAWSFMKPRFENL---CGRKL--VYAGRSEAPTPAVGASSLHRVEVEHVLK 17
+QEE +NMGA+ + +F + G KL Y GR E +PA G+ HR E ++K
Sbjct: 838 AQEEPKNMGAFQNVYFKFVEVVSKAGLKLGFEYVGRPERSSPATGSVYRHRTEQAEIIK 896
>UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=1; Neorickettsia sennetsu str. Miyayama|Rep:
2-oxoglutarate dehydrogenase, E1 component -
Neorickettsia sennetsu (strain Miyayama)
Length = 905
Score = 200 bits (488), Expect = 3e-50
Identities = 113/237 (47%), Positives = 148/237 (62%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+S ESKW+ +GLVMLLPHGY+G +EHSS R+ERFLQL A D+ + VAN
Sbjct: 681 ISSAESKWLSRSGLVMLLPHGYEGQGAEHSSARIERFLQL------AADNN---MRVANC 731
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPA +FH+LRRQV+ +PL++ PK LLR AVS L +F + F+PVI D +DA
Sbjct: 732 TTPANFFHVLRRQVLSEIVRPLVVFTPKSLLRHKMAVSKLEEFYEGS-FRPVISDYCSDA 790
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
K+ RVIF SGK YY+L E + E + +VRVE L P P E++ L Y++A +FIW
Sbjct: 791 KKIHRVIFCSGKVYYDLLAE---LKSESILLVRVEQLYPVPDREIREILDVYRDA-EFIW 846
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKEPL 8
QEE RNMG WSFM FE +KL Y GR+ P P+ G H ++K+ +
Sbjct: 847 CQEEPRNMGGWSFMLQVFEERYSKKLRYIGRNYYPVPSEGLMDDHIANQAALIKQAI 903
>UniRef50_Q4SL15 Cluster: Chromosome 17 SCAF14563, whole genome
shotgun sequence; n=4; Clupeocephala|Rep: Chromosome 17
SCAF14563, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 1054
Score = 198 bits (484), Expect = 9e-50
Identities = 118/257 (45%), Positives = 158/257 (61%), Gaps = 23/257 (8%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLT-DSPESAP----------- 575
I+SG++KWVR+NG+V+LLPHG +G EHSS R ERFLQ++ D P+ P
Sbjct: 788 ISSGQAKWVRNNGIVLLLPHGMEGMGPEHSSARPERFLQMSKDDPDHFPVRCGDLLSASL 847
Query: 574 DSEAACLH-----VANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDF 410
D E L+ N +TPA Y H+LRRQV+ +RKPLII PK LLR DA S D
Sbjct: 848 DFEVQQLYDCNWIAVNCSTPANYCHVLRRQVLLPFRKPLIIFTPKSLLRHPDARSSFDDL 907
Query: 409 APRTHFQPVIGD-GLA--DALKVKRVIFVSGKHYYELHKERVRARLE-DVAIVRVEALAP 242
T F+ +I D G A D +VKRVIF SGK YY+L KER +LE +VAIVR+E ++P
Sbjct: 908 TTGTKFKRLIPDEGPAGQDPARVKRVIFCSGKVYYDLAKERKDQKLEREVAIVRLEQISP 967
Query: 241 FPLPELQMQLSKYKNATKFIWSQEEHRNMGAWSFMKPRFEN-LCGRKLV-YAGRSEAPTP 68
FP ++ + KY +A + +W QEEH+NMG + +++PRF L RK + Y GR A P
Sbjct: 968 FPFDLVRTEAEKYVDA-ELVWCQEEHKNMGYYDYVRPRFLTVLANRKPIWYVGREPAAAP 1026
Query: 67 AVGASSLHRVEVEHVLK 17
A G S H E++ ++
Sbjct: 1027 ATGTRSTHLTELKRFVE 1043
>UniRef50_Q50992 Cluster: SucA protein; n=3; Neisseria|Rep: SucA
protein - Neisseria gonorrhoeae
Length = 582
Score = 198 bits (482), Expect = 2e-49
Identities = 107/242 (44%), Positives = 152/242 (62%), Gaps = 5/242 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+++GE+KW R GL +LPHGYDG EHSS R+ER+LQL + V P
Sbjct: 348 LSTGETKWGRLCGLTTILPHGYDGQGPEHSSARVERWLQLCSENN---------MQVIMP 398
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
+ +Q FHLL+RQV+ +YRKPL+I K LLR A+SPL +F + F+PVIGD A
Sbjct: 399 SEASQMFHLLQRQVLGSYRKPLVIFMSKRLLRFKGAMSPLENFTEGSTFRPVIGDTAERA 458
Query: 358 L--KVKRVIFVSGKHYYELHKERVRARLE-DVAIVRVEALAPFPLPELQMQLSKYKNATK 188
VKRV+ +G+ YY+L R +LE DVAIVRVE L PFP E++ +L+KY NA
Sbjct: 459 SNDSVKRVVLCAGQVYYDLEAGRAERKLEDDVAIVRVEQLYPFPYDEVKAELAKYPNAKS 518
Query: 187 FIWSQEEHRNMGAWSFMKPRFENLCG--RKLVYAGRSEAPTPAVGASSLHRVEVEHVLKE 14
+W+QEE +N GA+ ++ R E++ +KL Y GR + +PAVG SS H +++ ++++
Sbjct: 519 VVWAQEEPKNQGAFYQIRHRIEDVISEEQKLSYVGRPSSASPAVGYSSKHIAQLKQLVED 578
Query: 13 PL 8
L
Sbjct: 579 AL 580
>UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=1; Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Orientia tsutsugamushi
(strain Boryong) (Rickettsia tsutsugamushi)
Length = 963
Score = 198 bits (482), Expect = 2e-49
Identities = 102/241 (42%), Positives = 152/241 (63%), Gaps = 7/241 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+S E+KW + +V+LLPHGY+G EHSS R+ER+LQL + + V P
Sbjct: 722 ISSAETKWQMKSNIVLLLPHGYEGQGPEHSSARIERYLQLAVNNN---------IQVVYP 772
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPA +FHLLRRQ++ KPLI+++PK LLR +S L+D P+++FQ +I D + +
Sbjct: 773 TTPASFFHLLRRQIIGKIFKPLIVMSPKSLLRHKLVLSSLTDLGPQSYFQAII-DEIDPS 831
Query: 358 L--KVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKF 185
+ K+K+VI SGK +Y+L++ R + ++ +VAI+R+E PFP L L+KY +
Sbjct: 832 IQGKIKKVIICSGKLFYDLYEFRNKNKIANVAIIRIEQYFPFPTESLSTILAKYSVCDEI 891
Query: 184 IWSQEEHRNMGAWSFMKPRFENLCGR-----KLVYAGRSEAPTPAVGASSLHRVEVEHVL 20
IW QEE +NMGAW+F+KP E++ + KL Y GR A PAVG S LH + + ++
Sbjct: 892 IWCQEEPQNMGAWTFIKPYLEDIIDKAKKHIKLKYIGRDSASAPAVGYSYLHNKQQQELI 951
Query: 19 K 17
+
Sbjct: 952 Q 952
>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Brucella melitensis
Length = 1004
Score = 196 bits (479), Expect = 4e-49
Identities = 109/253 (43%), Positives = 159/253 (62%), Gaps = 16/253 (6%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+SGE KW+R +GLV LLPHG++G EHSS RLER+LQL A D+ + VAN
Sbjct: 761 ISSGERKWLRMSGLVCLLPHGFEGQGPEHSSARLERYLQLC-----AEDN----MQVANV 811
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDG---- 371
TTPA YFH+LRRQ+ R++RKPLI++ PK LLR A+S L++ + + F ++ D
Sbjct: 812 TTPANYFHILRRQMKRDFRKPLIMMTPKSLLRHKRAISTLAELSGESSFHRLLWDDAQYN 871
Query: 370 ------LADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLS 209
L K++RV+ SGK YY+L++ER + ++DV ++RVE L PFP L +LS
Sbjct: 872 KDEGIKLQKDAKIRRVVLCSGKVYYDLYEEREKRGIDDVYLLRVEQLYPFPAKALINELS 931
Query: 208 KYKNATKFIWSQEEHRNMGAWSFMKPRFENLCG------RKLVYAGRSEAPTPAVGASSL 47
++++A + +W QEE +NMGAWSF+ P E + +++ YAGR A +PA G S
Sbjct: 932 RFRHA-EMVWCQEEPKNMGAWSFIDPYLEWVLAHIDAKHQRVRYAGRPAAASPATGLMSK 990
Query: 46 HRVEVEHVLKEPL 8
H ++ L++ L
Sbjct: 991 HLAQLAAFLEDAL 1003
>UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Haemophilus influenzae
Length = 935
Score = 196 bits (478), Expect = 5e-49
Identities = 111/240 (46%), Positives = 147/240 (61%), Gaps = 3/240 (1%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+SGE KW R GLVMLLPHGY+G EHSS RLER+LQL A + C+ P
Sbjct: 704 ISSGEQKWGRMCGLVMLLPHGYEGQGPEHSSARLERYLQLC-----AEQNMQVCV----P 754
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGD-GLAD 362
+TPAQ +H+LRRQ +R R+PLI ++PK LLR AVS L + T FQ VIG+ D
Sbjct: 755 STPAQVYHMLRRQSLRKMRRPLIAISPKSLLRHPLAVSSLDELINGT-FQTVIGEIDELD 813
Query: 361 ALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFI 182
VKRV+ SGK YY+L ++R +DVAI+R+E L PFP +++ L Y + T ++
Sbjct: 814 PKDVKRVVMCSGKVYYDLLEQRRANNQKDVAIIRIEQLYPFPHEDVKKALEPYAHVTDYV 873
Query: 181 WSQEEHRNMGAWSFMKPRFENLCGR--KLVYAGRSEAPTPAVGASSLHRVEVEHVLKEPL 8
W QEE N GAW K FE+ KL YAGR + +PAVG SLH + + ++++ L
Sbjct: 874 WCQEEPLNQGAWYCSKHNFESAIPESVKLKYAGRPASASPAVGYMSLHTKQQKQLVEDAL 933
>UniRef50_Q9PD29 Cluster: Oxoglutarate dehydrogenase; n=17;
Bacteria|Rep: Oxoglutarate dehydrogenase - Xylella
fastidiosa
Length = 967
Score = 196 bits (477), Expect = 6e-49
Identities = 105/241 (43%), Positives = 148/241 (61%), Gaps = 2/241 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
IA+GE KW R +GL + LPHGY+G EHSS RLERFLQL A ++ C+ P
Sbjct: 729 IAAGEVKWGRISGLSLFLPHGYEGQGPEHSSARLERFLQLC-----ALENMLVCV----P 779
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPAQ FH++RRQ+ + RKPL+++ PK LLR AVS L + A FQ +I D AD
Sbjct: 780 TTPAQAFHMIRRQMRMSTRKPLVVMTPKSLLRHKLAVSTLDELA-NGKFQHIIPDDAADP 838
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
VKR++ +GK YY++ + + + D+AI+R+E L PFP L +L ++ AT +W
Sbjct: 839 KHVKRIVMCAGKVYYDILENQQKRSQNDLAIIRIEQLYPFPRALLASELKRFNKATDVVW 898
Query: 178 SQEEHRNMGAWSFMKPRFENLC--GRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKEPLY 5
QEE +N GAW +K + + ++L YAGRS +P+PAVG + H E E ++ + L
Sbjct: 899 CQEEPQNQGAWYQIKHHLQAVLAHAQRLHYAGRSSSPSPAVGHMAEHMAEQESLVADALL 958
Query: 4 N 2
N
Sbjct: 959 N 959
>UniRef50_Q1CZK3 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=2; Cystobacterineae|Rep: 2-oxoglutarate dehydrogenase,
E1 component - Myxococcus xanthus (strain DK 1622)
Length = 963
Score = 195 bits (476), Expect = 8e-49
Identities = 113/243 (46%), Positives = 145/243 (59%), Gaps = 6/243 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
IA+GESKW R +GL +LLPHGY+G EHSS RLERFL L A D+ C P
Sbjct: 724 IAAGESKWRRLSGLTLLLPHGYEGQGPEHSSARLERFLDLC-----AEDNIQVCY----P 774
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPAQ FHLLRRQV+R RKPL+I++PK LLR +A S + + A T FQ VI D + D
Sbjct: 775 TTPAQIFHLLRRQVLRPVRKPLVIMSPKSLLRRPEATSKVEELATGT-FQEVILDRV-DP 832
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
V R++ SGK YY+L K R + E +AIVR+E L PF L ++K + +W
Sbjct: 833 AGVTRLLLCSGKVYYDLVKARDERKDESIAIVRLEQLYPFASDVLAGLIAKMPKLAELLW 892
Query: 178 SQEEHRNMGAWSFMKPRFENLCGR------KLVYAGRSEAPTPAVGASSLHRVEVEHVLK 17
QEE RN GAW FM PR +L K+ Y GR+EA +PA G H E + +++
Sbjct: 893 VQEEPRNAGAWHFMFPRLHDLASTQSKQQVKIGYIGRAEAASPATGFPKTHEYEQQLIIE 952
Query: 16 EPL 8
E +
Sbjct: 953 EAI 955
>UniRef50_A2QL94 Cluster: Contig An06c0020, complete genome; n=2;
Aspergillus|Rep: Contig An06c0020, complete genome -
Aspergillus niger
Length = 456
Score = 195 bits (476), Expect = 8e-49
Identities = 112/253 (44%), Positives = 148/253 (58%), Gaps = 20/253 (7%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESA-PDSEA------- 563
+AS E KW++ +G+V+ LPHGYDG EH+S RLERFLQL D P +E
Sbjct: 194 VASSEKKWLQRSGVVLSLPHGYDGQGPEHTSARLERFLQLGDEDSRKFPSTEQLQRQHQD 253
Query: 562 ACLHVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPV 383
A + V T+PA YFH+LRRQ+ R++RKPLII+ K LLR A S + +F +FQP+
Sbjct: 254 ANIQVVCMTSPANYFHVLRRQIHRDFRKPLIILFSKSLLRHPLARSDIEEFIETPYFQPL 313
Query: 382 I-----GDGLADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQM 218
+ G + +KRVIF SG+ Y L+K R L+D AI R+E L PFP +++
Sbjct: 314 LPETQHGININKLEDIKRVIFCSGQVYAALYKYRETHGLKDTAITRIEELHPFPWEQVRQ 373
Query: 217 QLSKYKNATKFIWSQEEHRNMGAWSFMKPRF-------ENLCGRKLVYAGRSEAPTPAVG 59
L Y NAT +W QEE N GAWS++ PRF EN +K+ YAGR + AVG
Sbjct: 374 NLDNYPNATDVVWCQEETLNGGAWSYVMPRFEVILAKTENHTDKKIRYAGREPMSSVAVG 433
Query: 58 ASSLHRVEVEHVL 20
LH VE E +L
Sbjct: 434 YKVLHAVEEEKLL 446
>UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=2; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E1
component - Nitrosococcus oceani (strain ATCC 19707 /
NCIMB 11848)
Length = 940
Score = 194 bits (473), Expect = 2e-48
Identities = 108/239 (45%), Positives = 148/239 (61%), Gaps = 4/239 (1%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+ASGE+KW R GLV+ LPHGY+G EHSS RLERFLQL A D+ C+ P
Sbjct: 704 LASGEAKWSRLCGLVLFLPHGYEGQGPEHSSARLERFLQLC-----AEDNIQVCV----P 754
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIG--DGLA 365
TTP Q FH+LRRQ++R YRKPL+++ PK LLR +VS L +F F+ VIG D +
Sbjct: 755 TTPGQMFHMLRRQMLRPYRKPLVVMTPKSLLRHRLSVSSLDEFCSGA-FRLVIGEVDDIK 813
Query: 364 DALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKF 185
A+ V RVI +GK YY+L + R + +DVAI+R+E L PFP +L+ +L +Y+ A +
Sbjct: 814 PAM-VNRVILCAGKVYYDLLQARREQKRQDVAILRLEQLYPFPQQQLERELERYRKAREI 872
Query: 184 IWSQEEHRNMGAWSFMKPRFENLCGR--KLVYAGRSEAPTPAVGASSLHRVEVEHVLKE 14
+W QEE +N GAW + + R L Y GR+ + PAVG +LH + V++E
Sbjct: 873 VWCQEEPQNQGAWDQLHRPLQGCLSRNQSLHYTGRASSAAPAVGYFNLHLEQQRAVVEE 931
>UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component; n=4;
Bacteroidetes|Rep: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 946
Score = 194 bits (472), Expect = 3e-48
Identities = 108/234 (46%), Positives = 138/234 (58%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+ SGE+KW R NGLVM LPHGY+G EHSS RLERFL L + + V N
Sbjct: 711 VTSGETKWQRQNGLVMQLPHGYEGQGPEHSSARLERFLGLCANNN---------IIVTNI 761
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPA FH LRRQ+ +RKPLI +APK LLR VS L +F FQ VI D DA
Sbjct: 762 TTPANMFHALRRQLKWEFRKPLINMAPKSLLRHPLVVSDLKEFTSG-RFQEVIDDANVDA 820
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
KVKRV+F +GK YY+L +E+ A+ DVAIVR+E L P+P ++ KYK A +++W
Sbjct: 821 KKVKRVLFCTGKVYYDLFEEQKNAKRNDVAIVRIEQLYPYPEKQMAAVFEKYKGA-EYVW 879
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLK 17
QEE NMGAW ++ R + + R EA +PAVG H + ++K
Sbjct: 880 VQEEPYNMGAWGYILRRMYLMNNTGIEVIARDEASSPAVGYLKAHNEKQAELVK 933
>UniRef50_Q6MC85 Cluster: Probable 2-oxoglutarate dehydrogenase E1
component, sucA; n=1; Candidatus Protochlamydia
amoebophila UWE25|Rep: Probable 2-oxoglutarate
dehydrogenase E1 component, sucA - Protochlamydia
amoebophila (strain UWE25)
Length = 890
Score = 193 bits (471), Expect = 3e-48
Identities = 100/237 (42%), Positives = 140/237 (59%), Gaps = 2/237 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
IAS E KW + +GL++ LPHG +G EHSS RLERFL L L + N
Sbjct: 660 IASAEQKWGQKSGLILFLPHGLEGQGPEHSSGRLERFLTLAGHDN---------LQIVNT 710
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPAQ+FHLLRRQV + KPLI+ PK LLR VS L +F T F+ +I D A+
Sbjct: 711 TTPAQFFHLLRRQVKHQFEKPLIVFTPKGLLRYPKCVSALHEFTQGT-FREIIDDVFANP 769
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
++KR++ SG+ YY+L ER + +++ +R+E L P + EL+ + +Y + + +W
Sbjct: 770 SEIKRLVLCSGRIYYDLLAEREKLNQKEIGFIRIEQLYPLHMEELKKLIFQYPHIQEVVW 829
Query: 178 SQEEHRNMGAWSFMKPRFENLCGR--KLVYAGRSEAPTPAVGASSLHRVEVEHVLKE 14
+QEE +NMGAWSFM P L +L Y GR + TPA G+ LH E ++LK+
Sbjct: 830 AQEEPQNMGAWSFMFPYLNELISSSIQLSYVGRERSATPATGSYCLHNQEHANILKQ 886
>UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=13; Rickettsiales|Rep: 2-oxoglutarate dehydrogenase E1
component - Anaplasma marginale (strain St. Maries)
Length = 930
Score = 193 bits (470), Expect = 4e-48
Identities = 112/240 (46%), Positives = 151/240 (62%), Gaps = 7/240 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+A+ E+KW+RS+GLV+LLPHGY+G EHSS R+ER+LQL A D+ + V N
Sbjct: 701 VAAAETKWMRSSGLVLLLPHGYEGQGPEHSSARIERYLQL-----CAEDN----MQVVNC 751
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLAD- 362
TTPA +FH LRRQ+ R++RKPL++ PK LLR AVS +SDF HF PVIG+ +AD
Sbjct: 752 TTPANFFHALRRQLHRDFRKPLVVFTPKSLLRHKMAVSKISDF--EGHFIPVIGE-VADI 808
Query: 361 -ALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKF 185
V+RV+ SGK YY+L RA DVA++R+E PFP L +L+KYK A+
Sbjct: 809 NPSAVRRVVVCSGKVYYDL--LAARADKTDVALLRLEQYYPFPTELLANELAKYKKAS-V 865
Query: 184 IWSQEEHRNMGAWSFMKPRFEN--LC---GRKLVYAGRSEAPTPAVGASSLHRVEVEHVL 20
+W QEEH NMG WSF++ R E C + Y GRSE+ + A G S H + + ++
Sbjct: 866 VWCQEEHFNMGGWSFVRDRIEESMRCAGISGSVSYIGRSESASTAAGYPSAHATQQQAII 925
>UniRef50_Q02218 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor; n=77; Eumetazoa|Rep:
2-oxoglutarate dehydrogenase E1 component, mitochondrial
precursor - Homo sapiens (Human)
Length = 1002
Score = 193 bits (470), Expect = 4e-48
Identities = 107/242 (44%), Positives = 141/242 (58%), Gaps = 17/242 (7%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQL-TDSPESAPDSEAACLH--- 551
I G++KWVR NG+V+LLPHG +G EHSS R ERFLQ+ D P+ PD + A
Sbjct: 762 ICPGQAKWVRQNGIVLLLPHGMEGMGPEHSSARPERFLQMCNDDPDVLPDLKEANFDINQ 821
Query: 550 -------VANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHF 392
V N +TP +FH+LRRQ++ +RKPLII PK LLR +A S + P THF
Sbjct: 822 LYDCNWVVVNCSTPGNFFHVLRRQILLPFRKPLIIFTPKSLLRHPEARSSFDEMLPGTHF 881
Query: 391 QPVI---GDGLADALKVKRVIFVSGKHYYELHKER-VRARLEDVAIVRVEALAPFPLPEL 224
Q VI G + VKR++F +GK YY+L +ER R + VAI R+E L+PFP L
Sbjct: 882 QRVIPEDGPAAQNPENVKRLLFCTGKVYYDLTRERKARDMVGQVAITRIEQLSPFPFDLL 941
Query: 223 QMQLSKYKNATKFIWSQEEHRNMGAWSFMKPRFENLCGR--KLVYAGRSEAPTPAVGASS 50
++ KY NA + W QEEH+N G + ++KPR R + YAGR+ A PA G
Sbjct: 942 LKEVQKYPNA-ELAWCQEEHKNQGYYDYVKPRLRTTISRAKPVWYAGRNPAAAPATGNKK 1000
Query: 49 LH 44
H
Sbjct: 1001 TH 1002
>UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Anaeromyxobacter|Rep: 2-oxoglutarate dehydrogenase,
E1 subunit - Anaeromyxobacter sp. Fw109-5
Length = 940
Score = 192 bits (468), Expect = 8e-48
Identities = 100/237 (42%), Positives = 141/237 (59%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
++SGE+KW R +GL +LLPHG +G EHSS RLERFL+L S D+ V N
Sbjct: 697 LSSGEAKWNRLSGLALLLPHGMEGQGPEHSSARLERFLEL-----SVDDN----WRVVNL 747
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPAQYFH LRRQV +RKPL++++PK LLR VSPL D R FQPVI D AD
Sbjct: 748 TTPAQYFHALRRQVRSPFRKPLVVMSPKSLLRHPQVVSPL-DLLARERFQPVIDDESADP 806
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
+ RV+ SGK YY+L R AIVR+E L P + ++ +++ + + +W
Sbjct: 807 TETTRVVLCSGKLYYDLAGARTAQGARHAAIVRLEQLYPLDVESVRASIARLRPGVEIVW 866
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKEPL 8
+QEE NMGAW ++ ++ R+ + +PA G+++ HR+E E +++E L
Sbjct: 867 AQEEPSNMGAWDYVNAHLAPRLPSRVALVARAPSASPAAGSATRHRLEQEQLVREAL 923
>UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha-ketoglutarate
decarboxylase - Plesiocystis pacifica SIR-1
Length = 927
Score = 190 bits (463), Expect = 3e-47
Identities = 110/245 (44%), Positives = 147/245 (60%), Gaps = 10/245 (4%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
++S E KW R +GLVMLLPHGY+G EHSS RLERFLQ+ A D+ C N
Sbjct: 687 VSSSEDKWNRISGLVMLLPHGYEGQGPEHSSARLERFLQMC-----AEDNMQVC----NL 737
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAP-RTHFQPVIGDGLA- 365
TTP Q FH LRRQV+RN+RKPLI+++PK LLR + SP F P F+ VI D +
Sbjct: 738 TTPVQLFHALRRQVLRNWRKPLILMSPKSLLRFRPSFSPRERFLPGGGGFKRVISDEVTA 797
Query: 364 ----DALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPL--PELQMQLSKY 203
A KV+ V+ +GK +Y+L R + EDVA++RVE L PF +L Q+++Y
Sbjct: 798 GTKEAAAKVELVLVSAGKVHYDLRAAREEHKREDVALLRVEQLYPFARTGDDLAEQIARY 857
Query: 202 KNATKFIWSQEEHRNMGAWSFMKPRFENLCGR--KLVYAGRSEAPTPAVGASSLHRVEVE 29
NA W QEE RNMGAW F+ PR G + YAGR + +PA G+S H++E+
Sbjct: 858 PNAKAIRWVQEEPRNMGAWLFIYPRLLERFGADYSVSYAGRVSSASPATGSSEAHKMELA 917
Query: 28 HVLKE 14
+++
Sbjct: 918 RFVEQ 922
>UniRef50_UPI0000DAE34D Cluster: hypothetical protein Rgryl_01000074;
n=1; Rickettsiella grylli|Rep: hypothetical protein
Rgryl_01000074 - Rickettsiella grylli
Length = 929
Score = 189 bits (461), Expect = 5e-47
Identities = 104/239 (43%), Positives = 143/239 (59%), Gaps = 2/239 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
++S E KW R GLV+ LPH Y+G+ EH+S RLERFLQL A D+ C+ P
Sbjct: 700 LSSSEQKWGRLCGLVLFLPHAYEGSGPEHTSARLERFLQLC-----AQDNMQVCI----P 750
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
+TPAQ FH+LRRQ++R YRKPLI++ PK LLR AVS L + +Q VI D DA
Sbjct: 751 STPAQIFHVLRRQMLRPYRKPLILMTPKSLLRHKLAVSTLQALS-EGQWQSVISDFEVDA 809
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
+KRV+ SGK YY+L + R + + VA++R+E L PFP EL+ L + N +W
Sbjct: 810 NAIKRVVLCSGKVYYDLFEMRREQKQQGVALIRIEQLYPFPDIELKAALKPFSNVNDIVW 869
Query: 178 SQEEHRNMGAWSFMKPRFENLC--GRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKEPL 8
QEE +N GAW +++ + + L Y GRS + PAVG+ +H E ++KE L
Sbjct: 870 CQEESKNQGAWYWIQHHLISCLEKNQHLRYVGRSASAAPAVGSPLVHAEEQHTLIKEAL 928
>UniRef50_Q4UKI8 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=14; Rickettsia|Rep: 2-oxoglutarate dehydrogenase E1
component - Rickettsia felis (Rickettsia azadi)
Length = 977
Score = 189 bits (461), Expect = 5e-47
Identities = 105/243 (43%), Positives = 146/243 (60%), Gaps = 6/243 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+S E+KW+R +GLV+LLPH ++G EHSS RLERFLQL +A D+ ++V P
Sbjct: 744 ISSSETKWLRMSGLVVLLPHAFEGQGPEHSSARLERFLQL-----AAEDN----MYVTYP 794
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGD-GLAD 362
TTPA FHLLRRQ++ + RKPLII++PK LLR AVS L + T F PV+ + D
Sbjct: 795 TTPASIFHLLRRQILDDTRKPLIIMSPKSLLRHKYAVSKLDELGENTTFLPVLDEVNKVD 854
Query: 361 ALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFI 182
+ +VI SGK YY+L + +R ++AI+R+E L PF + L KY +FI
Sbjct: 855 TNNITKVILCSGKVYYDLFE--MRGNNSNIAIIRLEQLYPFEKKLVASLLKKYNRTQEFI 912
Query: 181 WSQEEHRNMGAWSFMKPRFENL-----CGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLK 17
W QEE +NMGAW ++ ++ + Y GR E+ +PAVG+ H + E +LK
Sbjct: 913 WCQEEPKNMGAWRYIVSHLNDVLKEAGINNEFKYVGREESASPAVGSLQAHNKQQEKLLK 972
Query: 16 EPL 8
E L
Sbjct: 973 EAL 975
>UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1
component family protein; n=1; Tetrahymena thermophila
SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component
family protein - Tetrahymena thermophila SB210
Length = 1054
Score = 189 bits (460), Expect = 7e-47
Identities = 107/263 (40%), Positives = 150/263 (57%), Gaps = 24/263 (9%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPES----------APDS 569
I SGESKW + +GLV+ LPHG DG EHSS RLERFLQL+D + S
Sbjct: 792 IVSGESKWKQQSGLVLNLPHGMDGQGPEHSSARLERFLQLSDDDPTNFILKRQNRLKQQS 851
Query: 568 EAACLHVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQ 389
L V TT A YFH LRRQ+ R +RKPL++ K LLR A A S L +F T F
Sbjct: 852 AEINLQVCMTTTAANYFHALRRQIRRPFRKPLVLFNSKRLLRFAGATSSLKEFQQGTRFL 911
Query: 388 PVIGD----GLADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQ 221
+ + + + K+K+V+ SG+ YY++ + R ++ ++ AI+R+E L+PFP L+
Sbjct: 912 DIYKEQYPQDINEPSKIKKVVLCSGQVYYDILERRQESKCKNTAIIRLEQLSPFPYEHLK 971
Query: 220 MQLSKYKNATKFIWSQEEHRNMGAWSFMKPRFENLCGR----------KLVYAGRSEAPT 71
+ L +YKNA K IW QEEH N G W+F++PR + R K++Y GR + +
Sbjct: 972 VVLEEYKNA-KIIWCQEEHENQGGWNFVRPRIRAVLDRLQEEGERKNGKVIYVGRKASCS 1030
Query: 70 PAVGASSLHRVEVEHVLKEPLYN 2
A G+SS H+ E+ L L+N
Sbjct: 1031 SAAGSSSKHKQELNLFLTH-LFN 1052
>UniRef50_Q4Q171 Cluster: 2-oxoglutarate dehydrogenase E1 component,
putative; n=6; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase E1 component, putative - Leishmania major
Length = 979
Score = 188 bits (459), Expect = 9e-47
Identities = 105/238 (44%), Positives = 148/238 (62%), Gaps = 8/238 (3%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPD-SEAACLHVAN 542
+++GESKW + ++ LPHGYDG +EHSS RLERFLQ++ + P S+ H N
Sbjct: 737 LSAGESKWNQQQSCIVTLPHGYDGKGAEHSSGRLERFLQMSSEDVTTPAYSKEERAHRIN 796
Query: 541 -----PTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIG 377
P+TPAQYFHLLRR RN+RK L+I K LR A VS L + FQPVI
Sbjct: 797 WEITYPSTPAQYFHLLRRHQKRNFRKALVIFFSKKYLR-APNVSTLEELTSG-EFQPVIP 854
Query: 376 DGLADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKN 197
D A + +R++ +G+ Y+ L+K R ++DVA+VRVE L+PFP+ E+Q L++Y+
Sbjct: 855 DLSVPASQARRLVMCTGQIYHYLNKYRETKGVKDVALVRVEELSPFPVAEVQQLLAEYEK 914
Query: 196 ATKFIWSQEEHRNMGAWSFMKPRFENLC--GRKLVYAGRSEAPTPAVGASSLHRVEVE 29
A + +W+QEE +NMG+W+ ++PR E+ R+L YAGRS P+ G S H E E
Sbjct: 915 A-ELMWAQEEPKNMGSWAHVEPRIEDYTKGERELRYAGRSITAAPSTGYKSKHEKEQE 971
>UniRef50_UPI00015B6161 Cluster: PREDICTED: hypothetical protein; n=1;
Nasonia vitripennis|Rep: PREDICTED: hypothetical protein
- Nasonia vitripennis
Length = 1012
Score = 188 bits (458), Expect = 1e-46
Identities = 104/246 (42%), Positives = 145/246 (58%), Gaps = 12/246 (4%)
Frame = -1
Query: 721 VIASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAA----CL 554
++ SG+SKW R GL++LLPHG +G EHSS RLERFLQL D DS+ +
Sbjct: 760 LLCSGQSKWGRQVGLILLLPHGMEGQGPEHSSARLERFLQLCDDEPGHDDSDDSPTRQLF 819
Query: 553 HV----ANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQP 386
HV N TTPA H LRRQ++ +RKPL+I+ PK LLR A S + P T F+P
Sbjct: 820 HVNWIVCNLTTPANLVHALRRQILMPFRKPLVIMTPKSLLRHPLAQSSFDEIGPGTSFRP 879
Query: 385 VIGDGLADALKVKRVIFVSGKHYYELHKERVRARLE-DVAIVRVEALAPFPLPELQMQLS 209
+I D V++++F SGK YYEL+ ER LE ++AI+RVE + PFP + Q+S
Sbjct: 880 LIPDQAVKPEGVRKILFCSGKVYYELYAERKEKGLENEIAILRVEQICPFPYRLVAEQVS 939
Query: 208 KYKNATKFIWSQEEHRNMGAWSFMKPRFE---NLCGRKLVYAGRSEAPTPAVGASSLHRV 38
KY K +W QEEHRN GA+ +++ R NL ++ + GR + +PA G+ ++
Sbjct: 940 KYPKC-KIMWLQEEHRNQGAYHYVRERLAHALNLSLEEVRFGGRPSSASPATGSKVIYEN 998
Query: 37 EVEHVL 20
E +L
Sbjct: 999 ERRDML 1004
>UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5;
Viridiplantae|Rep: OSIGBa0096P03.7 protein - Oryza sativa
(Rice)
Length = 1016
Score = 187 bits (456), Expect = 2e-46
Identities = 114/266 (42%), Positives = 155/266 (58%), Gaps = 29/266 (10%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDS-----PESAP----DSE 566
++SGE+KW+R GLV+ LPHGYDG EHSS RLERFLQ++D PE P +
Sbjct: 743 LSSGEAKWLRQTGLVVCLPHGYDGQGPEHSSARLERFLQMSDDNPYVIPEMDPTLRKQIQ 802
Query: 565 AACLHVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDF-------- 410
V N TTPA YFH+LRRQ+ R++RKPLI+++PK LLR D S LS+F
Sbjct: 803 QCNWQVVNVTTPANYFHVLRRQIHRDFRKPLIVMSPKNLLRHKDCKSNLSEFDDLAGHPG 862
Query: 409 --APRTHFQPVIGD--GLADALK-VKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALA 245
T F+ +I D D + +KR++ SGK YYEL +ER + +DVAI RVE L
Sbjct: 863 FDKQGTRFKRLIKDQNNHKDLEEGIKRLVLCSGKVYYELDEERRKKERDDVAICRVEQLC 922
Query: 244 PFPLPELQMQLSKYKNATKFIWSQEEHRNMGAWSFMKPRF---ENLCGRKLV----YAGR 86
PFP +Q +L +Y NA + +W QEE NMGA+S++ PR GR + Y GR
Sbjct: 923 PFPYDLIQRELKRYPNA-EIVWCQEEPMNMGAYSYINPRLLTAMRALGRGTIDDIKYVGR 981
Query: 85 SEAPTPAVGASSLHRVEVEHVLKEPL 8
+ + A G S+H E ++++ L
Sbjct: 982 APSAATATGFYSVHVQEQTELVQKAL 1007
>UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, whole
genome shotgun sequence; n=4; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_5, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 1002
Score = 186 bits (454), Expect = 4e-46
Identities = 104/254 (40%), Positives = 149/254 (58%), Gaps = 21/254 (8%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAAC------ 557
IAS ESKW +GLVMLLP+G DG EHSS R+ERFLQL+D + +
Sbjct: 744 IASAESKWDVDSGLVMLLPNGMDGQGPEHSSGRVERFLQLSDDDPAVFERNLGVRLKRQM 803
Query: 556 ----LHVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQ 389
+ + +TPA YFH LRRQ+ R++RKPLI + K LLRL A S L++F+ + F
Sbjct: 804 RNSNMQIVQCSTPANYFHSLRRQLRRDFRKPLIAMTSKKLLRLQAAKSKLNEFSEQARFS 863
Query: 388 PVIGDGLADAL----KVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQ 221
+ D + + +++RVI SG+ YY++ K+R ++++ AIVR+E LAPFP LQ
Sbjct: 864 QIYDDPFPELIDEPSQIQRVILCSGQVYYDILKKREELKVKNTAIVRIEQLAPFPYEFLQ 923
Query: 220 MQLSKYKNATKFIWSQEEHRNMGAWSFMKPRFEN-------LCGRKLVYAGRSEAPTPAV 62
+ KYK A F W QEEH+N G W+F++PR ++ L +++ Y GR + +PA
Sbjct: 924 TVIQKYKKA-HFAWVQEEHQNYGPWTFVRPRIQSVISKTQGLIQQQIQYIGRKPSGSPAT 982
Query: 61 GASSLHRVEVEHVL 20
G LH E + L
Sbjct: 983 GFHQLHEKEFQAFL 996
>UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E1
component; n=7; Bacteria|Rep: 2-oxoglutarate
dehydrogenase complex, E1 component - Azoarcus sp.
(strain EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 942
Score = 186 bits (452), Expect = 7e-46
Identities = 104/239 (43%), Positives = 144/239 (60%), Gaps = 5/239 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I SGE+KW R GL ++LPHGY+G EHSS R+ERF+ +A ++ C+ P
Sbjct: 706 ICSGEAKWGRLCGLTLMLPHGYEGQGPEHSSARIERFMN-----NAAENNWQICV----P 756
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLA-D 362
TTPAQ FHLLRRQ++R RKPL+I+ PK LLR +A S L++ F+ VIG+ A D
Sbjct: 757 TTPAQIFHLLRRQMLRKVRKPLVIITPKSLLRHKEATSTLAELEDGK-FRTVIGETEALD 815
Query: 361 ALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFI 182
KVKRV+ GK YYEL R ++D A+VR+E L PFP + ++ NA + +
Sbjct: 816 PKKVKRVVLCQGKLYYELLAYRRENNIKDTALVRIEQLYPFPAAAFGAAVDQFPNAREVV 875
Query: 181 WSQEEHRNMGAWSFMKPR--FENLCG--RKLVYAGRSEAPTPAVGASSLHRVEVEHVLK 17
W+QEE RN GAW ++ R N+ G RKL+ R A +PAVG + H + + V++
Sbjct: 876 WAQEEPRNQGAWYWLASRQHLVNVLGSKRKLLLVSRPAAASPAVGYYAKHNAQQKAVIE 934
>UniRef50_Q4AFR5 Cluster: Oxoglutarate dehydrogenase; n=1;
Chlorobium phaeobacteroides BS1|Rep: Oxoglutarate
dehydrogenase - Chlorobium phaeobacteroides BS1
Length = 508
Score = 185 bits (450), Expect = 1e-45
Identities = 102/237 (43%), Positives = 141/237 (59%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+S E KW N LV+LLPHGY+G EHSS R+ER+L L A ++ L +AN
Sbjct: 236 ISSAEDKWNVMNDLVVLLPHGYEGQGPEHSSARMERYLTL------AAENN---LQIANC 286
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPA +FHLLRRQ+ R +RKPLI+ PK LLR VSP+SDF F VI D +
Sbjct: 287 TTPANFFHLLRRQLHRPFRKPLIVFTPKSLLRHPLCVSPVSDFTSGK-FNEVIDDVSVNP 345
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
+V +V+F +GK YY+L ER + +A++R+E L PFPL ++ ++YK A IW
Sbjct: 346 EQVNKVVFCNGKLYYDLLAEREKLNNNRIALIRIEQLYPFPLEQILAINARYKKAKTHIW 405
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKEPL 8
+QEE NMGAW+F+ N KL+ R + +PA G+ H + + +L + L
Sbjct: 406 TQEEPANMGAWNFIYESLANQIPVKLI--ARPASGSPATGSGKFHVIRQQKILDKVL 460
>UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=16; cellular organisms|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Robiginitalea biformata
HTCC2501
Length = 940
Score = 185 bits (450), Expect = 1e-45
Identities = 98/233 (42%), Positives = 142/233 (60%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+++ E KW NGLV+ LPHGY+G +EHSS R+ER+LQL A D+ ++VA+
Sbjct: 696 LSAAEDKWKLQNGLVLFLPHGYEGQGAEHSSARMERYLQLC-----ARDN----MYVADV 746
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
+TPA FHLLRRQ++ N+RKPL++ PK LLR A VS + + A FQ VI D A
Sbjct: 747 STPANLFHLLRRQMLVNFRKPLVVFTPKSLLRHAKCVSTVEELA-EGRFQEVIDDAGASV 805
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
KVK ++F +GK YY+L R EDVA+VR+E L P P+ +++ + KY +A +W
Sbjct: 806 KKVKSLVFCTGKFYYDLLAAREELGREDVALVRLEQLFPLPVVQMEELIEKYSHAEDLVW 865
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVL 20
+QEE RNMGAWS + F + + A R +PA G+ + ++ + V+
Sbjct: 866 AQEEPRNMGAWSHLMMHFPD--ASRFRVASRRFYASPAAGSPARSKMRHQQVI 916
>UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
subunit - Solibacter usitatus (strain Ellin6076)
Length = 1220
Score = 184 bits (449), Expect = 2e-45
Identities = 104/245 (42%), Positives = 141/245 (57%), Gaps = 8/245 (3%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+ E KW + +GLVMLLPHGY+G EHSS R+ER+L L + V N
Sbjct: 966 ISCCEQKWGQPSGLVMLLPHGYEGQGPEHSSARIERYLTLCAENN---------MQVCNC 1016
Query: 538 TTPAQYFHLLRRQVV-----RNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGD 374
TTPAQYFHLLRRQ+ R RKPL+I PK LLR AVS L DF + + G
Sbjct: 1017 TTPAQYFHLLRRQMYGGSDRRGMRKPLVIFTPKSLLRHQKAVSTLHDFTTGGFTEILSGA 1076
Query: 373 GLADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNA 194
G+AD V RV+F SGK YY+L R + + VAI+RVE L PF + + L++Y
Sbjct: 1077 GVADNGLVSRVVFCSGKIYYDLLAAREERKADHVAIIRVEQLYPFAADQARDILARYAPT 1136
Query: 193 TKFIWSQEEHRNMGAWSFMKPRFENLCG---RKLVYAGRSEAPTPAVGASSLHRVEVEHV 23
+ +W+QEE RNMGAW F++ + + R++ Y GR E+ +PA G+ H+ E +
Sbjct: 1137 AEVVWAQEEPRNMGAWRFIRECLQAVLDDSRREIRYVGRPESASPATGSGKRHQQEQAEI 1196
Query: 22 LKEPL 8
+ + L
Sbjct: 1197 VNDAL 1201
>UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=1;
Blastopirellula marina DSM 3645|Rep: Alpha-ketoglutarate
dehydrogenase E1 - Blastopirellula marina DSM 3645
Length = 929
Score = 184 bits (448), Expect = 2e-45
Identities = 105/236 (44%), Positives = 136/236 (57%), Gaps = 2/236 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+ E KW R +G+VMLLPHGY+G EHSS RLERFL + A D+ + VA P
Sbjct: 699 ISGAEDKWNRLSGIVMLLPHGYEGQGPEHSSGRLERFLAI-----GAEDN----IQVAYP 749
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
+TPAQYFHLLRRQ +R +RKPL+I PK LLR AVS L++ A F+P++ D D
Sbjct: 750 STPAQYFHLLRRQTLRLWRKPLVIFTPKSLLRHPSAVSSLTELA-EGEFKPILPDETCDP 808
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
KV+RV+ +GK YYEL R +L+DVAI+R+E L P + L Y W
Sbjct: 809 AKVRRVLLCTGKLYYELDSYRNEHQLDDVAILRIEMLHPLRTGKFTDALKDYAADCPVTW 868
Query: 178 SQEEHRNMGAWSFMKPRF--ENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLK 17
QEE NMGAW RF + +L GR + +PA G+ S H E +L+
Sbjct: 869 VQEEPLNMGAWPHWATRFTGHRIDDHELNVVGRPRSASPATGSKSAHLWEQADLLE 924
>UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=149; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Azotobacter vinelandii
Length = 943
Score = 183 bits (446), Expect = 4e-45
Identities = 105/241 (43%), Positives = 139/241 (57%), Gaps = 6/241 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+SGE+KW GL MLLPHGY+G EHSS RLER+LQL A + C+ P
Sbjct: 709 ISSGETKWGALCGLTMLLPHGYEGQGPEHSSARLERYLQLC-----AEQNIQVCV----P 759
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGD-GLAD 362
TTPAQ +H+LRRQV+R RKPL+ + PK LLR A+S L D A + F PV+ + D
Sbjct: 760 TTPAQVYHMLRRQVIRPLRKPLVALTPKSLLRHKSAISTLEDLALGS-FHPVLPEVDSLD 818
Query: 361 ALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFI 182
KV+R++ SGK YY+L +R ED+AIVR+E L PFP EL ++ Y N +
Sbjct: 819 PKKVERLVLCSGKVYYDLLDKRHAEGREDIAIVRIEQLYPFPEEELAEVMAPYTNLKHVV 878
Query: 181 WSQEEHRNMGAWSFMKPRFENLCGRK-----LVYAGRSEAPTPAVGASSLHRVEVEHVLK 17
W QEE N GAW + + L YAGR + PA G +S+H + E +L+
Sbjct: 879 WCQEEPMNQGAWYCSQHHMRRVASAHKKELFLQYAGREASAAPACGYASMHAEQQEKLLQ 938
Query: 16 E 14
+
Sbjct: 939 D 939
>UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Alpha-ketoglutarate
decarboxylase - Lentisphaera araneosa HTCC2155
Length = 913
Score = 183 bits (445), Expect = 5e-45
Identities = 101/234 (43%), Positives = 135/234 (57%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+S ESKW R NGL LPHGY+G EHSS RLERFL L A ++ + VANP
Sbjct: 680 ISSAESKWQRMNGLTCFLPHGYEGQGPEHSSARLERFLSL------AAENN---MIVANP 730
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPA FHLLRRQ+ YR PLI++ PK LLR VSP+SD + + D + DA
Sbjct: 731 TTPANLFHLLRRQLKATYRIPLIVMTPKSLLRHPKVVSPVSDLTKGEFKETIDDDSVKDA 790
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
K++R+I SGK YYEL E+ + LE+VAIVR+E P P + KY + + W
Sbjct: 791 KKIERLILCSGKIYYELLDEKEKQGLENVAIVRIEQFYPTPKDQDTALHKKYGHCKDWYW 850
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLK 17
QEE +NMG W +M+ R ++L + + R ++ +PA G E ++K
Sbjct: 851 VQEEPQNMGGWYYMRARLDHL-RHDMKFISRKKSASPANGLMKREIAFQEKIIK 903
>UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=4;
Bacteria|Rep: Alpha-ketoglutarate dehydrogenase E1 -
Rhodopirellula baltica
Length = 969
Score = 182 bits (444), Expect = 6e-45
Identities = 97/236 (41%), Positives = 141/236 (59%), Gaps = 2/236 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
IAS E KW R +GLVMLLPHG++G EH S R+ERFL + +A D+ + + P
Sbjct: 737 IASAEDKWNRLSGLVMLLPHGFEGQGPEHCSARVERFLAM-----AAEDN----IQICQP 787
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPAQYFHLLRRQV+R +RKPLI++ PK LLR A+ SPL D F+ ++ D
Sbjct: 788 TTPAQYFHLLRRQVIRKWRKPLIVLTPKSLLRHAEVTSPL-DVVAEGSFRKILPDRKVPL 846
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
KR++ +GK YY+L +ER +EDV I+R+E L P E+ ++ W
Sbjct: 847 EGAKRLVLCTGKVYYDLLQERTDRNIEDVPIMRLEQLYPLSPDEIFAAFEGLAEGSEIRW 906
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVY--AGRSEAPTPAVGASSLHRVEVEHVLK 17
QEE NMGAW ++K + + ++ + A R+E+ +P+ G+ + H++E +LK
Sbjct: 907 VQEEPENMGAWPYLKLKIGDELNKRFRFTKATRAESASPSTGSMAAHKLEQIDLLK 962
>UniRef50_Q1IKU2 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=1; Acidobacteria bacterium Ellin345|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Acidobacteria bacterium
(strain Ellin345)
Length = 820
Score = 182 bits (444), Expect = 6e-45
Identities = 97/233 (41%), Positives = 141/233 (60%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+ +GE KW +G+V+LLPHG++G EHSS R+ER+LQL A D+ C P
Sbjct: 591 LVAGEDKWDLLSGVVLLLPHGHEGQGPEHSSARIERYLQLC-----ARDNMQVC----QP 641
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
+ AQYFHLLRRQ +R +RKPL+ PK +LR +AVSPLSD + HF+ V+ D +
Sbjct: 642 SNAAQYFHLLRRQALRKWRKPLVCFTPKSMLRHPEAVSPLSDLT-KPHFETVVPDH--EV 698
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
+R++ +GK +EL ER R R AI+ ++ + PFP EL+ L+++ NA F+W
Sbjct: 699 QNAERLLLCTGKIGHELRMERRRRRDTSTAILSLDQIYPFPENELEAALAQHPNARDFVW 758
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVL 20
QEE NMGA SF++PR + G + R+ + TPA G+ H +E + +L
Sbjct: 759 VQEEPANMGALSFVEPRLHRIIGPGVRTIKRAASATPATGSHKAHELEQKTLL 811
>UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=11; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Coxiella burnetii
Length = 934
Score = 182 bits (444), Expect = 6e-45
Identities = 107/242 (44%), Positives = 144/242 (59%), Gaps = 5/242 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+SG KW R +G+V+ LPHGY+G EHSS RLER+LQL A ++ C P
Sbjct: 701 ISSGWQKWNRLSGIVLFLPHGYEGKGPEHSSARLERYLQLC-----AQNNMQVCA----P 751
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGD-GLAD 362
TTP+Q FHLLRRQV+R YRKPL+++ PK +LR AVS L D A R + +I + D
Sbjct: 752 TTPSQIFHLLRRQVLRPYRKPLVVLTPKSVLRNKLAVSSLEDLA-RGQLKLLIPEIEKHD 810
Query: 361 ALKVKRVIFVSGKHYYELHKER--VRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATK 188
K+ RVI SGK YY+L +R + +L +A++R+E L PFP EL+ +L KY NA +
Sbjct: 811 PKKITRVILCSGKVYYDLLAKRREHKGKLNHIAMIRIEQLYPFPYDELKAELEKYPNAKQ 870
Query: 187 FIWSQEEHRNMGAWSFMKPRFENLC--GRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKE 14
IW QEE +N GAW + R + L Y GRS PA G S+L+ E ++ +
Sbjct: 871 VIWCQEEPKNQGAWFCTRHRLIKCMRDDQTLEYVGRSAFAAPAAGYSALYVKLQEQLVNQ 930
Query: 13 PL 8
L
Sbjct: 931 AL 932
>UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr13 scaffold_17, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 973
Score = 182 bits (442), Expect = 1e-44
Identities = 109/257 (42%), Positives = 149/257 (57%), Gaps = 20/257 (7%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
++SGESKW+R GLV+LLPHGYDG EHSS RLERFLQ + + N
Sbjct: 718 LSSGESKWLRQTGLVVLLPHGYDGQGPEHSSARLERFLQ---------QIQECNWQIVNV 768
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDF----------APRTHFQ 389
TTPA YFH+LRRQ+ R +RKPLI+++PK LLR D S LS+F T F+
Sbjct: 769 TTPANYFHVLRRQIHREFRKPLIVMSPKNLLRHKDCKSNLSEFDDVQGHPGFDKQGTRFK 828
Query: 388 PVIGD-GLADALK--VKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQM 218
+I D +L+ ++R+I SGK YYEL ++R + + DVAI RVE L PFP Q
Sbjct: 829 RLIKDQNDHSSLEEGIRRLILCSGKVYYELDEQRKKVKANDVAICRVEQLCPFPYDLAQR 888
Query: 217 QLSKYKNATKFIWSQEEHRNMGAWSFMKPRF-------ENLCGRKLVYAGRSEAPTPAVG 59
+L +Y NA + +W QEE NMGA++++ PR + + Y GR+ + A G
Sbjct: 889 ELKRYPNA-EIVWCQEEPMNMGAYNYILPRLCTAMKEVDRGTVEDVKYVGRAPSAATATG 947
Query: 58 ASSLHRVEVEHVLKEPL 8
SSLH E ++++ L
Sbjct: 948 FSSLHTKEQTELVQKAL 964
>UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albicans
CaKGD1 2-oxoglutarate dehydrogenase; n=4; Ascomycota|Rep:
Similar to CA3149|CaKGD1 Candida albicans CaKGD1
2-oxoglutarate dehydrogenase - Debaryomyces hansenii
(Yeast) (Torulaspora hansenii)
Length = 997
Score = 181 bits (440), Expect = 2e-44
Identities = 106/259 (40%), Positives = 143/259 (55%), Gaps = 20/259 (7%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTD-------SPESAP-DSEA 563
I++ ESKW + +GLV+ LPHGYDG EHSS R+ER+LQL + SPE +
Sbjct: 739 ISAAESKWKQRSGLVLSLPHGYDGQGPEHSSGRIERYLQLCNEDQRYFPSPELLERQHQD 798
Query: 562 ACLHVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQ-- 389
A + VA PTTPA FHLLRRQ+ R +RKPL++ K LLR A S LS+F +HFQ
Sbjct: 799 ANMQVAYPTTPANIFHLLRRQMHRQFRKPLVLFFSKQLLRHPLAKSELSEFTGESHFQWI 858
Query: 388 ---PVIGDGLADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQM 218
P +G + +KRVI SG+ + LHK+R + A +++E L PFP +L+
Sbjct: 859 IEDPELGKSINAKEDIKRVILCSGQVFTALHKKRADIEDKSTAFIKIEQLHPFPFAQLRD 918
Query: 217 QLSKYKNATKFIWSQEEHRNMGAWSFMKPRF-------ENLCGRKLVYAGRSEAPTPAVG 59
L Y +W QEE NMG++S+ PR E + L YAGR + + A G
Sbjct: 919 ALDSYPALEDLVWCQEEPLNMGSYSYSAPRIATVLENTEKHKDKSLRYAGRDPSASVAAG 978
Query: 58 ASSLHRVEVEHVLKEPLYN 2
++H E E LKE N
Sbjct: 979 TKAMHNSEEEEFLKEVFQN 997
>UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=45; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Corynebacterium glutamicum (Brevibacterium
flavum)
Length = 1257
Score = 180 bits (438), Expect = 3e-44
Identities = 96/238 (40%), Positives = 142/238 (59%), Gaps = 3/238 (1%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
++SGE+KW +++ L++LLPHGY+G +HSS R+ERFLQL +E + + VA P
Sbjct: 1025 VSSGEAKWGQTSKLILLLPHGYEGQGPDHSSARIERFLQLC--------AEGS-MTVAQP 1075
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGD-GLAD 362
+TPA +FHLLRR + + ++PL+I PK +LR A S DF T FQ VI D +AD
Sbjct: 1076 STPANHFHLLRRHALSDLKRPLVIFTPKSMLRNKAAASAPEDFTEVTKFQSVINDPNVAD 1135
Query: 361 ALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFI 182
A KVK+V+ VSGK YYEL K + + +D+AIVR+E L P P + L+ Y NA + +
Sbjct: 1136 AAKVKKVMLVSGKLYYELAKRKEKDGRDDIAIVRIEMLHPIPFNRISEALAGYPNAEEVL 1195
Query: 181 WSQEEHRNMGAWSFMKPRFENLCGR--KLVYAGRSEAPTPAVGASSLHRVEVEHVLKE 14
+ Q+E N G W F + L K+ R + A G + +H++E + ++ E
Sbjct: 1196 FVQDEPANQGPWPFYQEHLPELIPNMPKMRRVSRRAQSSTATGVAKVHQLEEKQLIDE 1253
>UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=15; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
component - Deinococcus radiodurans
Length = 956
Score = 179 bits (435), Expect = 8e-44
Identities = 104/241 (43%), Positives = 146/241 (60%), Gaps = 4/241 (1%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+++GESKW R +GL MLLPHGY+GA EHSS RLER+LQL + V P
Sbjct: 706 LSAGESKWQRLSGLTMLLPHGYEGAGPEHSSARLERYLQLCAQKN---------MQVVVP 756
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
++ AQ FHLLRRQV+R YRKPLI++ PK LLR A+SPLSD F VIGD A+
Sbjct: 757 SSAAQIFHLLRRQVLRPYRKPLIVMTPKSLLRNKHAMSPLSDLYDGV-FHEVIGD--AEV 813
Query: 358 LKVKRVIFVSGKHYYEL--HKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKF 185
+RV+ SGK ++EL +E+ + A+VR+E L PFP +++ +L+K+ A +
Sbjct: 814 QNARRVVLSSGKLHWELTEAREKDKEGYAGTALVRLEQLYPFPAEQVKAELAKHPGA-QV 872
Query: 184 IWSQEEHRNMGAWSFMKPRFENLC--GRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKEP 11
+W+QEE N GAW + E+ G+ L +A R + + AVG +S+H E V+ +
Sbjct: 873 VWAQEEPENQGAWLMIWEDLEHCLQPGQTLTHASRPRSASTAVGYTSVHVREQAKVIADA 932
Query: 10 L 8
L
Sbjct: 933 L 933
>UniRef50_UPI000051A0C7 Cluster: PREDICTED: similar to CG33791-PC,
isoform C; n=1; Apis mellifera|Rep: PREDICTED: similar to
CG33791-PC, isoform C - Apis mellifera
Length = 980
Score = 178 bits (433), Expect = 1e-43
Identities = 96/253 (37%), Positives = 145/253 (57%), Gaps = 19/253 (7%)
Frame = -1
Query: 721 VIASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDS-----PESAPDSEAAC 557
+++SG++KW R GLV+LLPHG +G EHSS ++ER+L+L D P + P
Sbjct: 722 ILSSGQTKWGRQVGLVLLLPHGLEGQGPEHSSAKIERYLELCDDDFSYLPTAEPGETIDQ 781
Query: 556 LH----------VANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFA 407
+ + N TTPA +FH+LRRQ+ +RKPL I+ PK LLR A+SP +D
Sbjct: 782 IMTRQLFEINWIICNLTTPANFFHVLRRQIHMPFRKPLCIMTPKSLLRHPMALSPFADME 841
Query: 406 PRTHFQPVIGDGLADALKVKRVIFVSGKHYYELHKERVRARLED-VAIVRVEALAPFPLP 230
T F+P++ D +++V+ SG+ +Y+L ER +L D +AI+R+E L PFP
Sbjct: 842 SGTSFKPILSDPFVKPGNIQKVLMCSGRVFYDLVTERQGKQLVDKIAIIRIEQLCPFPYH 901
Query: 229 ELQMQLSKYKNATKFIWSQEEHRNMGAWSFMKPRFENLCG---RKLVYAGRSEAPTPAVG 59
L ++ KY NA K +W QEEH+N G + +++ R G L Y GR + +PA G
Sbjct: 902 LLAEEMKKYPNA-KLMWLQEEHKNQGPYLYVRDRIALALGIRLEDLAYGGRPPSSSPATG 960
Query: 58 ASSLHRVEVEHVL 20
+ +HR E ++
Sbjct: 961 SKVIHRNEYNDMI 973
>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=3; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
component - Salinibacter ruber (strain DSM 13855)
Length = 1243
Score = 177 bits (432), Expect = 2e-43
Identities = 104/245 (42%), Positives = 140/245 (57%), Gaps = 8/245 (3%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+++ E KW +++GLV LLPH Y+G EHSS RLERFLQL + VAN
Sbjct: 1008 VSAAEEKWGQTSGLVALLPHAYEGQGPEHSSARLERFLQLCAEQN---------MIVANF 1058
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
+TPA YFH LRRQV R+ +KPLII+ PK LLR VS D Q +I AD
Sbjct: 1059 STPANYFHALRRQVKRDVKKPLIIMTPKSLLRHPKCVSTPEDLM-EGGVQEII-PAEADP 1116
Query: 358 LKVKRVIFVSGKHYYELHKERVRA-RLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFI 182
R I SGK YY+L R +++AI R+E PFP +LQ +L +Y A + +
Sbjct: 1117 AGTMRHILCSGKVYYDLVTALEDTDRRDEIAITRLEQFYPFPESDLQEELERYAEADETV 1176
Query: 181 WSQEEHRNMGAWSFMKPRFENL-------CGRKLVYAGRSEAPTPAVGASSLHRVEVEHV 23
W QEE +NMGAWSF+ PRFE L C +++ Y GR + +PA G++ +H E E +
Sbjct: 1177 WVQEEPQNMGAWSFVSPRFETLLDEIHGPCEQRIQYVGRPASASPATGSAKVHDREQEQL 1236
Query: 22 LKEPL 8
+ + L
Sbjct: 1237 VGDAL 1241
>UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=11; Francisella tularensis|Rep: 2-oxoglutarate
dehydrogenase E1 component - Francisella tularensis
subsp. tularensis (strain FSC 198)
Length = 941
Score = 177 bits (430), Expect = 3e-43
Identities = 100/239 (41%), Positives = 139/239 (58%), Gaps = 2/239 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+ + E KW +GL + LPHG +GA +EHSS RLERFL A D+ C P
Sbjct: 712 LVAAEEKWGILSGLTLFLPHGQEGAGAEHSSARLERFLN-----SCANDNMQVC----TP 762
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPAQ +HLLRRQV+R RKPLI++ PK LLR AVS L + + + F+ +I D A A
Sbjct: 763 TTPAQIYHLLRRQVIRPLRKPLIVMTPKSLLRNPMAVSSLQELS-QGKFEAIIDDVNAKA 821
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
KV ++I +GK YY+L ++ + E +A+VR+E L PFP +L +KY N K +W
Sbjct: 822 AKVTKLILCNGKVYYDLMAKK-QDNYEHIAVVRLEELYPFPQQQLAQIFTKYNNVNKVVW 880
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRK--LVYAGRSEAPTPAVGASSLHRVEVEHVLKEPL 8
QEE N GAW ++ E L +K L+ R + TPAVG +L+ + E ++ L
Sbjct: 881 LQEEPENKGAWYNIRHFIEKLVDKKQELLCVARERSSTPAVGYHALYVKQQEEIINTAL 939
>UniRef50_Q23KH1 Cluster: 2-oxoglutarate dehydrogenase, E1 component
family protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E1 component family protein
- Tetrahymena thermophila SB210
Length = 992
Score = 177 bits (430), Expect = 3e-43
Identities = 101/261 (38%), Positives = 154/261 (59%), Gaps = 26/261 (9%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTD--------SPESAPDSEA 563
+ASGE+KW GLV+LLPHG DG EHSS R+ERFLQ+ D P++ +
Sbjct: 730 LASGEAKWNVQTGLVVLLPHGMDGQGPEHSSGRMERFLQMCDDDIQSAISQPKTRQRGQG 789
Query: 562 ACLH--VANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTH-- 395
++ V + A YFH LRRQ+ R++RKPLI K LLR A S + +F T
Sbjct: 790 RKINWSVICCSFSANYFHALRRQMHRDFRKPLIAFTSKKLLRFKPACSNIKEFTEFTDNP 849
Query: 394 --FQPVI--GDGLADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPE 227
F+ V+ + + ++ +VK+V+ SG+ Y++L + R + D+AIVR+E +APFP +
Sbjct: 850 NLFKNVVPETEKIVESSQVKKVVICSGQVYWDLVEYRQEHKKNDIAIVRIEQIAPFPYED 909
Query: 226 LQMQLSKYKNATKFIWSQEEHRNMGAWSFMKPRFE----------NLCGRKLVYAGRSEA 77
++ + YKNA +FIW QEEH N GAW++++PR E ++ KL Y GR
Sbjct: 910 IRSAIQNYKNA-EFIWCQEEHENSGAWTYIEPRLEIILDELKSEGSIKHNKLNYIGRKRQ 968
Query: 76 PTPAVGASSLHRVEVEHVLKE 14
+ A G++ +H++E+E +LK+
Sbjct: 969 ASTATGSTKVHKLELESILKK 989
>UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial, putative; n=9; Plasmodium|Rep:
2-oxoglutarate dehydrogenase E1 component, mitochondrial,
putative - Plasmodium vivax
Length = 1059
Score = 176 bits (428), Expect = 5e-43
Identities = 92/212 (43%), Positives = 121/212 (57%), Gaps = 13/212 (6%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAP------DSEAAC 557
IASGE+KW + +G+VM LPHGYDG EHSS R+ERFLQL D E D
Sbjct: 759 IASGETKWNKQSGIVMFLPHGYDGQGPEHSSARIERFLQLCDDREDIATYSVEKDKTIIQ 818
Query: 556 LH---VANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQP 386
H V N T P+ FH LRRQ+ R++RKPLI + PK +L++ A + +F P T F P
Sbjct: 819 QHNMQVINCTKPSNLFHALRRQMHRSFRKPLIAITPKKMLKMRMAFDTIENFLPPTEFLP 878
Query: 385 VIGDG----LADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQM 218
+ + L D +KR+I SG+ YY+L R ++DVAI +E L+PFP +
Sbjct: 879 YLPEQQEHKLNDKEHIKRIILCSGQVYYDLLNYREANEIKDVAIATIEQLSPFPFKQFMQ 938
Query: 217 QLSKYKNATKFIWSQEEHRNMGAWSFMKPRFE 122
L +Y N IW QEEH NMG W ++ R E
Sbjct: 939 DLQRYPNLRDVIWVQEEHMNMGPWFYVSRRIE 970
>UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=1; Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Dichelobacter nodosus
(strain VCS1703A)
Length = 917
Score = 175 bits (427), Expect = 7e-43
Identities = 97/238 (40%), Positives = 136/238 (57%), Gaps = 1/238 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+SG SKW + GL + LPHG++G SEHSS RLER+LQL + V NP
Sbjct: 687 ISSGASKWGQDCGLTLFLPHGFEGQGSEHSSARLERYLQLCAQHN---------MRVCNP 737
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
TTPAQ FHLLR+Q+ + R+PLI++ PK LLR A+SP++ T + +
Sbjct: 738 TTPAQIFHLLRQQLHQRARRPLIVMTPKSLLRHKLAISPITALTAGTFVNVFDDAAIENP 797
Query: 358 LKVKRVIFVSGKHYYEL-HKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFI 182
KV+RVI SGK YY+L K R + +A++R+E L PFP L + L Y +A + I
Sbjct: 798 EKVRRVILCSGKIYYDLWQKRREQGDEHTIALIRLEQLYPFPADALALILKNY-SAAELI 856
Query: 181 WSQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKEPL 8
W QEE RN GAW ++ + +L R + Y GR+ + + AVG + H E + + L
Sbjct: 857 WCQEEPRNQGAWRYLYECWHDLSERSIRYIGRAASASTAVGDAKRHLAEQNTFITQAL 914
>UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 component ,
putative; n=1; Babesia bovis|Rep: 2-oxoglutarate
dehydrogenase E1 component , putative - Babesia bovis
Length = 891
Score = 174 bits (423), Expect = 2e-42
Identities = 89/247 (36%), Positives = 139/247 (56%), Gaps = 14/247 (5%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPES-------APDSEAA 560
+ SGE+KW + + + + LPHG+DG +HSS R+ER+LQL++ PE + D A
Sbjct: 638 VVSGEAKWAQKSAMCLFLPHGFDGQGPDHSSARIERYLQLSNEPEDVSEFVSMSTDDHAR 697
Query: 559 CLHVA--NPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQP 386
+++A N T + FH LRRQ++R+ RKPLI++ K LL+L + +F P F+P
Sbjct: 698 RVNIAVINCTRSSNLFHALRRQMLRDMRKPLIVMTGKKLLKLRGTYCNIEEFGPSYGFRP 757
Query: 385 VIGDGLADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSK 206
+I +++ V +I SG+ Y+++ + +VA+ VE L PFP L+ +L +
Sbjct: 758 MIPASVSNEDAVDTLILCSGQVYFDISDRVSELSVGNVAVTTVEQLCPFPAGALKSELER 817
Query: 205 YKNATKFIWSQEEHRNMGAWSFMKPRFENL-----CGRKLVYAGRSEAPTPAVGASSLHR 41
Y N + +W QEEH N G WS++ PR +L G +L Y GR P+ G S H
Sbjct: 818 YPNLKRLVWCQEEHANAGGWSYVSPRICSLLAHLGSGLRLEYVGRPPLSAPSCGDSRTHG 877
Query: 40 VEVEHVL 20
VE++ L
Sbjct: 878 VELQKFL 884
>UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 1304
Score = 171 bits (416), Expect = 2e-41
Identities = 97/236 (41%), Positives = 134/236 (56%), Gaps = 1/236 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+ S E KW + LVMLLPHGY+G +HSS R+ER+LQL +A ++ + + P
Sbjct: 1076 VCSAEQKWGQRCSLVMLLPHGYEGQGPDHSSARIERYLQL-----AAQEN----MWIVQP 1126
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGD-GLAD 362
+TPA YFH+LR Q + RKPLI PK LLRL+ A S L +F FQPVIGD + +
Sbjct: 1127 STPANYFHMLRTQAYKRPRKPLIAFTPKQLLRLSAASSHLDEFTSGA-FQPVIGDSSITN 1185
Query: 361 ALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFI 182
V RV+ SG+ YY+L KER AI+R+E L P P E+ L++Y NA+
Sbjct: 1186 PSSVTRVLLCSGRLYYDLMKEREHRGDTSTAIIRLEQLYPLPEAEVAETLAQYPNAS-VT 1244
Query: 181 WSQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKE 14
W Q+E RN GAW + GR + R E+ T A G +SLH+ + ++ +
Sbjct: 1245 WVQDEPRNQGAWPHLALNLFPSLGRPVRVVSRPESATTAAGRASLHKEQAATLIAQ 1300
>UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=5; Enterobacteriaceae|Rep: 2-oxoglutarate dehydrogenase
E1 component - Escherichia coli (strain UTI89 / UPEC)
Length = 939
Score = 171 bits (415), Expect = 2e-41
Identities = 102/237 (43%), Positives = 136/237 (57%), Gaps = 4/237 (1%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+SGE+KW R +GL +LLPHGYDG EHSS R ER+LQL + V P
Sbjct: 704 ISSGETKWDRYSGLTILLPHGYDGQGPEHSSARPERWLQLCAENN---------MQVVMP 754
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGD-GLAD 362
+ AQ FHLLR Q +R RKPL+I+ K LLR A+S LS+F ++PV+ D L
Sbjct: 755 SESAQMFHLLRGQALRPMRKPLVIMMSKRLLRFKGAMSELSEFTDGA-YKPVVTDPQLHQ 813
Query: 361 ALKVKRVIFVSGKHYYELHKERVRARLED-VAIVRVEALAPFPLPELQMQLSKYKNATKF 185
+ KVKRVI SG+ YY++ + R + ED VAIVR+E L PFP+ EL L+ + N ++
Sbjct: 814 SQKVKRVILCSGQVYYDVLEARKQRECEDEVAIVRLEQLYPFPVAELNDVLASWPNCCEW 873
Query: 184 IWSQEEHRNMGAWSFMKPRFENLCGRK--LVYAGRSEAPTPAVGASSLHRVEVEHVL 20
IW QEE N GAW ++ L YAGR PA G +H+ +++ L
Sbjct: 874 IWLQEEPENQGAWRQIRHELAALKINTPYWQYAGRPAVAAPATGYGRVHKQQIDEFL 930
>UniRef50_Q6BGE2 Cluster: 2-oxoglutarate dehydrogenase, putative; n=4;
Paramecium tetraurelia|Rep: 2-oxoglutarate dehydrogenase,
putative - Paramecium tetraurelia
Length = 964
Score = 171 bits (415), Expect = 2e-41
Identities = 99/256 (38%), Positives = 148/256 (57%), Gaps = 23/256 (8%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDS-PESAPDSEAACL---- 554
I SGESKW +GLVM+LPHG DG EHSS R+ERFLQL D P + +
Sbjct: 705 ITSGESKWNVPSGLVMMLPHGLDGQGPEHSSGRMERFLQLMDDDPNIVFQMKEQRIKRQI 764
Query: 553 -----HVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQ 389
V + P+ YFH LRRQ+ R++RKPLI+ K LL+ + A S +S F T F
Sbjct: 765 LDSNFQVCVCSNPSNYFHSLRRQLRRDFRKPLILFNSKRLLKFSKATSDISLFLEGTRFH 824
Query: 388 PVIGD---GLADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQM 218
+I D + ++K+V+ G+ YY++ ++R + DVAIVRVE LAPFP ++
Sbjct: 825 RLIPDTHEEIKAPKEIKKVVICYGQVYYDILQKRQETKRNDVAIVRVEQLAPFPYDHFRV 884
Query: 217 QLSKYKNATKFIWSQEEHRNMGAWSFMKPRFENLCG----------RKLVYAGRSEAPTP 68
+Y+NA +F++ QEEH+N GAW +++PR +N+ + L + GR + +
Sbjct: 885 VAQQYENA-EFVFCQEEHQNSGAWQYLEPRIQNVLSLLHQQSKIKHQYLTFCGRRPSAST 943
Query: 67 AVGASSLHRVEVEHVL 20
A G+ ++H+ E+E +L
Sbjct: 944 ASGSPTVHKQELEKLL 959
>UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor; n=34; Fungi/Metazoa group|Rep:
2-oxoglutarate dehydrogenase E1 component, mitochondrial
precursor - Saccharomyces cerevisiae (Baker's yeast)
Length = 1014
Score = 171 bits (415), Expect = 2e-41
Identities = 103/255 (40%), Positives = 137/255 (53%), Gaps = 20/255 (7%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLT-DSPESAPDSEAA------ 560
IA GE KW + +GLV+ LPHGYDG EHSS RLERFLQL + P P E
Sbjct: 756 IAGGEQKWKQRSGLVLSLPHGYDGQGPEHSSGRLERFLQLANEDPRYFPSEEKLQRQHQD 815
Query: 559 C-LHVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPV 383
C V PTTPA FH+LRRQ R +RKPL + K LLR A S LS+F FQ +
Sbjct: 816 CNFQVVYPTTPANLFHILRRQQHRQFRKPLALFFSKQLLRHPLARSSLSEFT-EGGFQWI 874
Query: 382 I-----GDGLADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQM 218
I G + + KR++ +SG+ Y LHK R + A +++E L PFP +L+
Sbjct: 875 IEDIEHGKSIGTKEETKRLVLLSGQVYTALHKRRESLGDKTTAFLKIEQLHPFPFAQLRD 934
Query: 217 QLSKYKNATKFIWSQEEHRNMGAWSFMKPRFENLCGR-------KLVYAGRSEAPTPAVG 59
L+ Y N + +W QEE NMG+W++ +PR K+ Y GR+ + A G
Sbjct: 935 SLNSYPNLEEIVWCQEEPLNMGSWAYTEPRLHTTLKETDKYKDFKVRYCGRNPSGAVAAG 994
Query: 58 ASSLHRVEVEHVLKE 14
+ SLH E + LK+
Sbjct: 995 SKSLHLAEEDAFLKD 1009
>UniRef50_Q8K9N3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=4; Enterobacteriaceae|Rep: 2-oxoglutarate dehydrogenase
E1 component - Buchnera aphidicola subsp. Schizaphis
graminum
Length = 923
Score = 171 bits (415), Expect = 2e-41
Identities = 98/235 (41%), Positives = 132/235 (56%), Gaps = 2/235 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+S E KW + + LV+ LPHGY+G EHSS RLERFLQL A ++ C+ P
Sbjct: 690 ISSSEQKWNQKSNLVLFLPHGYEGQGPEHSSARLERFLQLC-----AENNIQVCI----P 740
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
T +Q FHLLRRQ+ N KPLI++ PK LLR A S L + +F+ VI + +
Sbjct: 741 TVSSQIFHLLRRQIFSNVYKPLIVLTPKSLLRNNVARSSL-EVLVNENFKNVINEIDKNQ 799
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
+VKR+IF SGK YY+L + R + + +V ++R+E L PFP E+ L Y FIW
Sbjct: 800 KEVKRIIFCSGKIYYDLLEYRNKCDINNVLLIRIEQLYPFPKDEILTILKSYSYVQDFIW 859
Query: 178 SQEEHRNMGAWSFMKPRFENL--CGRKLVYAGRSEAPTPAVGASSLHRVEVEHVL 20
QEE N GAW ++K L L Y R A +PA G +HR E E ++
Sbjct: 860 CQEEPHNQGAWFYIKDLLSTLLPLNSHLNYVSRPSAASPAAGHILIHRKEQEKLI 914
>UniRef50_A4S835 Cluster: Predicted protein; n=1; Ostreococcus
lucimarinus CCE9901|Rep: Predicted protein - Ostreococcus
lucimarinus CCE9901
Length = 730
Score = 167 bits (405), Expect = 3e-40
Identities = 98/262 (37%), Positives = 145/262 (55%), Gaps = 25/262 (9%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I SGE +W + + +V+LLPHGY+G +HS+ R PE + ++A + V P
Sbjct: 471 ICSGEERWGQRSDIVLLLPHGYEGQGPDHSTAR----------PEPSVMAQANFVMV-QP 519
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLA-- 365
+TPAQYFH LRRQ+ + KPL+++ PK LL S L DFAP++ F+ VI DG A
Sbjct: 520 STPAQYFHALRRQISSPHSKPLVVLTPKTLLHHKHCASKLMDFAPKSSFRRVIADGDAGD 579
Query: 364 DALK-----------VKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQM 218
D + +KRVI +GK YY L ++R +++DVAI+R+E L PFP L
Sbjct: 580 DVTRHENIPLKPNGEIKRVILCTGKIYYSLARQRAAKKIDDVAIIRLEQLFPFPHDALAR 639
Query: 217 QLSKYKNATKFIWSQEEHRNMGAWSFMKPRFENL------------CGRKLVYAGRSEAP 74
+L +Y NA +W+QEE +NMG WSF+ PR R++ + GR +
Sbjct: 640 RLQRYPNA-HLVWAQEEPKNMGYWSFVAPRIATTERATRVRASVDEENRRVRFVGRPPSA 698
Query: 73 TPAVGASSLHRVEVEHVLKEPL 8
PA G+ ++H E ++ + L
Sbjct: 699 APATGSLAIHNAENARLIAQAL 720
>UniRef50_Q5L172 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=8; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Geobacillus kaustophilus
Length = 950
Score = 167 bits (405), Expect = 3e-40
Identities = 104/242 (42%), Positives = 146/242 (60%), Gaps = 8/242 (3%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+SG +KW + +GLVMLLPHGY+G EHSS R+ERFLQL +A ++ VAN
Sbjct: 712 ISSGRAKWGQKSGLVMLLPHGYEGQGPEHSSGRVERFLQL-----AAENNWT----VANL 762
Query: 538 TTPAQYFHLLRRQ---VVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGD-G 371
+T AQYFH+LRRQ + R +PLII+ PK LLR A S F F PV+ G
Sbjct: 763 STAAQYFHILRRQAALLTREEVRPLIIMTPKSLLRHPLAASDAEVFVDGA-FSPVLEQPG 821
Query: 370 L-ADALKVKRVIFVSGKHYYELHKERVRAR-LEDVAIVRVEALAPFPLPELQMQLSKYKN 197
L ADA KV+R++F +GK +L ++ + L+ + IVR+E L PFP ++ +++Y N
Sbjct: 822 LGADAGKVERIVFGTGKLMIDLAEQIGKMESLDWLHIVRIEELYPFPEEAVKDIIARYPN 881
Query: 196 ATKFIWSQEEHRNMGAWSFMKPRFENLC--GRKLVYAGRSEAPTPAVGASSLHRVEVEHV 23
+ +W QEE +NMGAW +M+PR L G + Y GR +PA G +HR E E +
Sbjct: 882 VKELVWVQEEPKNMGAWLYMEPRLRALAPEGVDVSYIGRRRRASPAEGDPVVHRKEQERI 941
Query: 22 LK 17
++
Sbjct: 942 IR 943
>UniRef50_Q23MM6 Cluster: 2-oxoglutarate dehydrogenase, E1 component
family protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E1 component family protein
- Tetrahymena thermophila SB210
Length = 1004
Score = 164 bits (398), Expect = 2e-39
Identities = 103/274 (37%), Positives = 143/274 (52%), Gaps = 36/274 (13%)
Frame = -1
Query: 736 NNSGRV-----IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQL--TD----- 593
NNS +V + E KW R + L +LLPHG DGA EHSSCR+ERFLQ+ TD
Sbjct: 722 NNSAQVAIDTFLTCSEHKWARQSSLTLLLPHGMDGAGPEHSSCRMERFLQMGNTDGIDRN 781
Query: 592 ----------SPESAPDSEAACLH------VANPTTPAQYFHLLRRQVVRNYRKPLIIVA 461
SP D + H + NPTTPA YFH LRRQ+ RNYRKPL++V
Sbjct: 782 LTYAGYNPNRSPSKVEDQQFYMSHQDVNFQLINPTTPANYFHALRRQMHRNYRKPLVVVG 841
Query: 460 PKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADALKVKRVIFVSGKHYYELHKERVRARL 281
PK L+R A S D +T F+ +I L K K +I ++GK Y+++ + +A
Sbjct: 842 PKTLIRHQLAKSTFEDMGEQTRFKEII-QRLEVNHKTKNIIIMTGKFQYDVYNQIEQANK 900
Query: 280 ED-VAIVRVEALAPFPLPELQMQLSKY-KNATKFIWSQEEHRNMGAWSFMKPRFENLC-- 113
+D A+V +E L PFP +L+ L+K + W QEEH N GA+ + +P +
Sbjct: 901 QDTTALVVLEELLPFPEEQLKTILAKADAHHANIYWVQEEHINSGAYVYSEPHIARIIRE 960
Query: 112 ----GRKLVYAGRSEAPTPAVGASSLHRVEVEHV 23
+K+ Y GR +P A G S H E++ +
Sbjct: 961 LKFKNQKITYVGRKASPATATGRSKEHPQELKQI 994
>UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate
dehydrogenase E1 component - Blochmannia floridanus
Length = 970
Score = 161 bits (390), Expect = 2e-38
Identities = 91/241 (37%), Positives = 138/241 (57%), Gaps = 4/241 (1%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+SGE KW + GL+MLLPHGY+G EHSSCR+ER+LQL + + P
Sbjct: 732 ISSGEQKWNQLCGLIMLLPHGYEGQGPEHSSCRIERYLQLCSEYN---------MRICIP 782
Query: 538 TTPAQYFHLLRRQVVRNYR-KPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLAD 362
+TP Q +HLL + R KPLIIV+PK LLR + + DF + F+ +I + +
Sbjct: 783 STPDQIYHLLHQHAHDKIRRKPLIIVSPKSLLRHPMVHASIEDFTYGS-FKAIISETNNN 841
Query: 361 AL--KVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATK 188
+ +V ++I +GK YY+L +R + + ++AI+R+E L PFP ++++ L Y +
Sbjct: 842 CILTQVNKIIICTGKIYYDLVNKRNQLKKYNIAIIRIEQLYPFPHVDIKIILKPYLHVEN 901
Query: 187 FIWSQEEHRNMGAWSFMKPRFEN-LCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLKEP 11
FIW QEE +N GAW +++ F + L Y GR EA PA G S H+ + ++ +
Sbjct: 902 FIWCQEEPQNQGAWYYIQLYFHKYIPNITLNYMGRDEAAAPASGYFSQHQQQQTKIINQA 961
Query: 10 L 8
L
Sbjct: 962 L 962
>UniRef50_Q81TK1 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=20; Bacillaceae|Rep: 2-oxoglutarate dehydrogenase E1
component - Bacillus anthracis
Length = 955
Score = 153 bits (372), Expect = 3e-36
Identities = 96/248 (38%), Positives = 139/248 (56%), Gaps = 11/248 (4%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
+++G +KW + +GLV+LLPHGY+G EHSS R ERFLQL A ++ VAN
Sbjct: 700 VSAGRAKWGQKSGLVLLLPHGYEGQGPEHSSARPERFLQL------AAENNWT---VANL 750
Query: 538 TTPAQYFHLLRRQVV---RNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIG-DG 371
T+ AQYFH+LRRQ +PL+++ PK LLR +S + + FQP + +
Sbjct: 751 TSAAQYFHILRRQASILGTEAVRPLVLMTPKSLLRHPLTLSTANQLS-EGRFQPALEQEN 809
Query: 370 LADAL-KVKRVIFVSGKHYYELHKE----RVRARLEDVAIVRVEALAPFPLPELQMQLSK 206
L KVKR++ +GK +L E R L+++ IVR+E L PFP ++Q + +
Sbjct: 810 LGTKPNKVKRLVLSTGKMAIDLAAEIESGRHEYNLDEIHIVRIEQLYPFPAEKVQSIIKR 869
Query: 205 YKNATKFIWSQEEHRNMGAWSFMKPRFENLCGRKLV--YAGRSEAPTPAVGASSLHRVEV 32
+KN + IW QEE RNMGAW +M P L G K+ Y GR + +P+ G H+ E
Sbjct: 870 FKNLEEIIWVQEEPRNMGAWHYMAPILFELAGDKVKTGYIGRPDRSSPSGGDPFAHKAEQ 929
Query: 31 EHVLKEPL 8
E ++ L
Sbjct: 930 ELIVSHAL 937
>UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit,
putative; n=7; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase subunit, putative - Trypanosoma brucei
Length = 1008
Score = 153 bits (370), Expect = 6e-36
Identities = 95/268 (35%), Positives = 142/268 (52%), Gaps = 31/268 (11%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDS-EAAC----- 557
+ GE KW LV+ LPHGY GA EHSS R+ER+LQL + P + C
Sbjct: 741 LCCGEEKWNAKYSLVLSLPHGYSGAGPEHSSARIERYLQLCSDTDVVPHNFRRGCPLQLL 800
Query: 556 --------LHVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPR 401
V P+TPA YFH+LRRQV R KPL++ K LR A VS LS+ +
Sbjct: 801 EVRIQRFNWQVCYPSTPANYFHVLRRQVRRGDPKPLVVFFSKARLR-APNVSSLSEMSTG 859
Query: 400 THFQPVIGDGLADALKVKRVIFVSGKHYYELHKERVRARLE------DVAIVRVEALAPF 239
T F+PVI + D + ++V+F +G+ + R + + E DV +V++E L+PF
Sbjct: 860 TSFKPVIDTAVNDEVIARKVLFCTGQIESIVDDRRKKLQAEKPGVHDDVVLVKLEQLSPF 919
Query: 238 PLPELQMQLSKYKNA---TKFIWSQEEHRNMGAWSFMKPRFENL------CGRK--LVYA 92
P ++ L KY + +F W QEE +NMG+W++++PR + L G L Y
Sbjct: 920 PWEQVADVLEKYHSRNPNVQFAWLQEEPKNMGSWAYVRPRLQRLLRHLGMAGSSDFLPYV 979
Query: 91 GRSEAPTPAVGASSLHRVEVEHVLKEPL 8
GR A +P+ G +++H E ++++ L
Sbjct: 980 GRVTAASPSTGYATVHAEEEAEIIRQAL 1007
>UniRef50_A0BCX8 Cluster: Chromosome undetermined scaffold_10, whole
genome shotgun sequence; n=1; Paramecium tetraurelia|Rep:
Chromosome undetermined scaffold_10, whole genome shotgun
sequence - Paramecium tetraurelia
Length = 893
Score = 150 bits (364), Expect = 3e-35
Identities = 87/245 (35%), Positives = 130/245 (53%), Gaps = 6/245 (2%)
Frame = -1
Query: 730 SGRVIASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLH 551
S I E KW+R + LV+LLPHGYDGA EHSS R+ER+LQ ++
Sbjct: 654 SDTFITCAEEKWMRQSSLVLLLPHGYDGAGPEHSSSRMERWLQQGVQNQN--------FQ 705
Query: 550 VANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDG 371
A P++P+ FH+LRRQ+ R +RKPL+I K LLR A D FQ +I
Sbjct: 706 FAIPSSPSSIFHILRRQMHRQFRKPLVIANAKSLLRSNKAKCTFEDLGEDKSFQRIITHK 765
Query: 370 LADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNAT 191
D + +VIF GK Y+L ++ + + E L PFP EL++ L +
Sbjct: 766 QGD--RPNKVIFTYGKFVYDLLEQLEKKNASNYVTFTFEQLLPFPKQELELGLKQLDKDV 823
Query: 190 KFIWSQEEHRNMGAWSFMKPRFENL------CGRKLVYAGRSEAPTPAVGASSLHRVEVE 29
KF + QEE +N G ++ + + + + + L Y GR E P+ AVGA+ LH+ E++
Sbjct: 824 KFYFVQEEPQNQGGLNYCQLQIDQVLTSLQFTNKSLNYIGRPECPSVAVGATVLHKQELQ 883
Query: 28 HVLKE 14
+++K+
Sbjct: 884 NIVKQ 888
>UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 component,
putative; n=2; Theileria|Rep: 2-oxoglutarate
dehydrogenase e1 component, putative - Theileria parva
Length = 1030
Score = 150 bits (363), Expect = 4e-35
Identities = 90/264 (34%), Positives = 137/264 (51%), Gaps = 35/264 (13%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDS--------EA 563
+ S E+KW +GLV+ LPHGYDG +HSS R+ERFLQL++ E D+ +
Sbjct: 758 VTSAETKWNYFSGLVLFLPHGYDGQGPDHSSSRIERFLQLSNDNEDLVDNLKYGDDYAKL 817
Query: 562 ACLHVANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPV 383
+ V N + + +FH+LRRQ+ R+YRKP+I + K LL+L + S + ++ T F+
Sbjct: 818 VNISVVNCSVASNFFHVLRRQMHRSYRKPMICITGKKLLKLRSSFSTIDEYLTGTRFRRY 877
Query: 382 IGDGLADALK--------------VKRVIFVSGKHYYELHKER-VRARLEDVAIVRVEAL 248
I D L K VKR+I SG+ YY+L + R +++ + R+E +
Sbjct: 878 IPDNLFTTGKQDLSKEEKPRNPDSVKRMIMCSGQIYYDLLEYRDSNEEWKNIPVARIEEI 937
Query: 247 APFPLPELQMQLSKYKNATKFIWSQEEHRNMGAWSFMKPRFENL---------CGR---K 104
PFP + L K+KN +W QEEH N G + F++ R N+ C +
Sbjct: 938 TPFPAQNILDDLKKFKNLETLVWCQEEHENSGCFYFLRERLNNVLKILKNEGHCPKVNTA 997
Query: 103 LVYAGRSEAPTPAVGASSLHRVEV 32
+ Y+GR T AVG +H E+
Sbjct: 998 VKYSGRYPCATTAVGDPKMHEHEI 1021
>UniRef50_A0FRW7 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Burkholderiaceae|Rep: 2-oxoglutarate dehydrogenase,
E1 subunit - Burkholderia phymatum STM815
Length = 891
Score = 149 bits (362), Expect = 5e-35
Identities = 89/206 (43%), Positives = 119/206 (57%), Gaps = 2/206 (0%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
IA+GE KW + L +LLPHG++G EHSS L RFLQL A D+ L V P
Sbjct: 656 IAAGEYKWGYQSALTVLLPHGHEGVGPEHSSGYLGRFLQLC-----AGDN----LRVVVP 706
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAV-SPLSDFAPRTHFQPVIGD-GLA 365
+T AQ+FHLLR Q +PL++++PK L A SPLSDF + F P++ D G+
Sbjct: 707 STSAQWFHLLREQARAEPAQPLVVMSPKSQLHGNCASHSPLSDFIDGS-FNPILPDPGIV 765
Query: 364 DALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKF 185
D V RV+ SGK +YEL + R +R A+VRVE L PFP L LS ++ +
Sbjct: 766 DPRVVTRVVLCSGKLFYELQRARDESRDTSTALVRVEQLYPFPHDALASLLSGFEKLEEV 825
Query: 184 IWSQEEHRNMGAWSFMKPRFENLCGR 107
+W+QEE RN GAW F++ E + R
Sbjct: 826 VWAQEEDRNQGAWRFVREALEQVLPR 851
>UniRef50_Q5L672 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=7; Chlamydiaceae|Rep: 2-oxoglutarate dehydrogenase E1
component - Chlamydophila abortus
Length = 908
Score = 144 bits (348), Expect = 3e-33
Identities = 79/228 (34%), Positives = 121/228 (53%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I+S KW + LV+LLPHGY+G EHSS R+ER+LQL + V P
Sbjct: 677 ISSAIQKWDLHSDLVVLLPHGYEGQGPEHSSARIERYLQLAANWN---------FQVVIP 727
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADA 359
+TP QYF +LR R+ PL+I PK+LLR + +S + +F F+P++ D +
Sbjct: 728 STPVQYFRILREHTKRDLSLPLVIFTPKMLLRHPECISWIDEFTEPGGFRPILEDAEPN- 786
Query: 358 LKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFIW 179
K + SGK YY+ + R +D A +R+E+L P L +L + KY ++W
Sbjct: 787 YDAKVFVLCSGKVYYDFKGALPQERKKDFACLRIESLYPLHLEDLLSVIGKYPKVEHYVW 846
Query: 178 SQEEHRNMGAWSFMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVE 35
QEE +NMGA+ ++ E + +KL R + + A G++ L + E
Sbjct: 847 LQEEPQNMGAYDYIFMATEEIFPKKLTCVSRPRSSSTATGSARLSQQE 894
>UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=17; Staphylococcus|Rep: 2-oxoglutarate dehydrogenase E1
component - Staphylococcus aureus
Length = 932
Score = 141 bits (342), Expect = 1e-32
Identities = 84/242 (34%), Positives = 126/242 (52%), Gaps = 5/242 (2%)
Frame = -1
Query: 712 SGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANPTT 533
S SKW +GL + LPH Y+G EHSS RLERFLQL +E C V N ++
Sbjct: 701 SSRSKWGERSGLTLFLPHAYEGQGPEHSSARLERFLQLA--------AENNCT-VVNLSS 751
Query: 532 PAQYFHLLRRQVVR---NYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLAD 362
+ YFHLLR Q +PL++++PK LLR P+ +F F+P++ +
Sbjct: 752 SSNYFHLLRAQAASLDSEQMRPLVVMSPKSLLRNKTVAKPIDEFTSGG-FEPILTESY-Q 809
Query: 361 ALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFI 182
A KV +VI +GK + +L + + E V +V +E L PFP E++ L++ +
Sbjct: 810 ADKVTKVILATGKMFIDLKEALAKNPDESVLLVAIERLYPFPEEEIEALLAQLPKLEEVS 869
Query: 181 WSQEEHRNMGAWSFMKPRFENLCGRK--LVYAGRSEAPTPAVGASSLHRVEVEHVLKEPL 8
W QEE +N GAW ++ P + L K L Y GR + PA G +H++ +++ L
Sbjct: 870 WVQEEPKNQGAWLYVYPYVKVLVADKYDLSYHGRIQRAAPAEGDGEIHKLVQNKIIENAL 929
Query: 7 YN 2
N
Sbjct: 930 KN 931
>UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E1 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 933
Score = 139 bits (337), Expect = 6e-32
Identities = 92/240 (38%), Positives = 126/240 (52%), Gaps = 6/240 (2%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFLQLTDSPESAPDSEAACLHVANP 539
I SG KW S+ LV++LPHGY+G EHSS RLER+LQL A + C+ P
Sbjct: 692 ITSGLQKWGVSSSLVIMLPHGYEGQGPEHSSGRLERYLQLC-----AQKNIQICI----P 742
Query: 538 TTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLA-DAVSPLSDFAPRTHFQPVIGDGLAD 362
TT +Q +HLL +Q + + PLII PK LLR +S F + H +
Sbjct: 743 TTASQIYHLLLKQGQKFLKTPLIIFTPKSLLRHPLTFISIKKLFIEKFHKILLFKKKNIS 802
Query: 361 ALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKNATKFI 182
+ RVIF +GK YYEL + + + I+R+E L PFP ++ L+KY N FI
Sbjct: 803 LDLISRVIFCNGKIYYELLDFYEKNNIINSIIIRIEQLYPFPFYKINKILNKYINIKYFI 862
Query: 181 WSQEEHRNMGAWS-----FMKPRFENLCGRKLVYAGRSEAPTPAVGASSLHRVEVEHVLK 17
WSQEE N G+W F K F N +KL Y GRS+ + A G H+ + + ++K
Sbjct: 863 WSQEEPENQGSWKHIYFYFKKYIFNNNEKKKLQYVGRSKLASTAEGNFENHQKKQKKIIK 922
>UniRef50_Q00UK1 Cluster: Predicted 2-oxoglutarate dehydrogenase, E1
subunit; n=3; cellular organisms|Rep: Predicted
2-oxoglutarate dehydrogenase, E1 subunit - Ostreococcus
tauri
Length = 1210
Score = 139 bits (336), Expect = 8e-32
Identities = 78/204 (38%), Positives = 116/204 (56%), Gaps = 23/204 (11%)
Frame = -1
Query: 550 VANPTTPAQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDG 371
+ P+TPAQYFH+LRR + + KPL+I+ PK LL S L DFAP++ F+ VI DG
Sbjct: 915 LVQPSTPAQYFHVLRRHMSSPHTKPLVILTPKTLLHHKYCASKLMDFAPKSSFRRVIADG 974
Query: 370 -------------LADALKVKRVIFVSGKHYYELHKERVRARLEDVAIVRVEALAPFPLP 230
L A ++KRV+ +GK YY+L ++R+ +++D+AIVR+E L PFP
Sbjct: 975 DAGDDVTRHESIPLKPANEIKRVVLCTGKMYYQLARQRLAKKIDDIAIVRLEQLFPFPHD 1034
Query: 229 ELQMQLSKYKNATKFIWSQEEHRNMGAWSFMKPRFENL--CGR--------KLVYAGRSE 80
L +L +Y NA +W+QEE +NMG W+++ PR R +L Y GR
Sbjct: 1035 ALARRLQRYPNA-HLVWAQEEPKNMGYWAYVAPRIATTERATRTRATSDISRLRYVGRPP 1093
Query: 79 APTPAVGASSLHRVEVEHVLKEPL 8
A + A G+ ++H E V+ + L
Sbjct: 1094 AASAATGSFAIHTTETASVINQAL 1117
Score = 59.3 bits (137), Expect = 1e-07
Identities = 29/65 (44%), Positives = 40/65 (61%), Gaps = 1/65 (1%)
Frame = -1
Query: 718 IASGESKWVRSNGLVMLLPHGYDGAASEHSSCRLERFL-QLTDSPESAPDSEAACLHVAN 542
I SGE +W + + LV+LLPHGY+G +HSS R ER+L D P++ P + AA + A
Sbjct: 765 ICSGEERWGQRSNLVLLLPHGYEGQGPDHSSARPERWLAAANDDPDALPGNAAADIAFAE 824
Query: 541 PTTPA 527
T A
Sbjct: 825 RTFEA 829
>UniRef50_Q3KTJ4 Cluster: SJCHGC05401 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC05401 protein - Schistosoma
japonicum (Blood fluke)
Length = 61
Score = 44.0 bits (99), Expect = 0.004
Identities = 22/58 (37%), Positives = 35/58 (60%), Gaps = 8/58 (13%)
Frame = -1
Query: 157 MGAWSFMKPR-----FENLCGR---KLVYAGRSEAPTPAVGASSLHRVEVEHVLKEPL 8
MGAWS+++PR F+ + GR K+++AGR + A G ++H +E+ H LK L
Sbjct: 1 MGAWSYVQPRVNHLIFKTMPGRLHNKILFAGRQPSAATAAGNKAMHLMEISHYLKNAL 58
>UniRef50_Q7NGX0 Cluster: Gll2767 protein; n=17; Bacteria|Rep:
Gll2767 protein - Gloeobacter violaceus
Length = 260
Score = 33.9 bits (74), Expect = 4.2
Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 4/88 (4%)
Frame = -1
Query: 529 AQYFHLLRRQVVRNYRKPLIIVAPKLLLRLADAVSPLSDFAPRTHFQPVIGDGLADALKV 350
A YFH + + R+P ++ +LLR ADA+ +D P + DG+ + +
Sbjct: 157 ALYFHHTWKNHLERSREPFALIKDHVLLRFADALGE-ADARMSERVTPQVIDGIVERIPE 215
Query: 349 KRV----IFVSGKHYYELHKERVRARLE 278
+ FV G+ + E +++ + RLE
Sbjct: 216 AWLGADSPFVGGEQHREAYRKYLLRRLE 243
>UniRef50_Q9FG37 Cluster: Gamma-tubulin interacting protein-like;
n=5; Magnoliophyta|Rep: Gamma-tubulin interacting
protein-like - Arabidopsis thaliana (Mouse-ear cress)
Length = 838
Score = 33.5 bits (73), Expect = 5.6
Identities = 18/51 (35%), Positives = 23/51 (45%), Gaps = 2/51 (3%)
Frame = -1
Query: 277 DVAIVRVEALAPFPLPELQMQLSKYKNATKFIW--SQEEHRNMGAWSFMKP 131
DV + EA P + LSKY F+W + EH +G W MKP
Sbjct: 578 DVFSLEYEARVPLDTVFTESVLSKYLRVFNFLWKLKRVEHALIGIWKTMKP 628
>UniRef50_A7P438 Cluster: Chromosome chr1 scaffold_5, whole genome
shotgun sequence; n=2; Vitis vinifera|Rep: Chromosome
chr1 scaffold_5, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 729
Score = 33.5 bits (73), Expect = 5.6
Identities = 19/42 (45%), Positives = 25/42 (59%), Gaps = 2/42 (4%)
Frame = -1
Query: 688 SNGLVMLLPHGYDGAASEHS--SCRLERFLQLTDSPESAPDS 569
+NG +++ HG DG AS S SC +ERF L+ SP DS
Sbjct: 499 NNGFILV--HGLDGFASHLSPFSCNVERFATLSFSPPQPSDS 538
>UniRef50_Q6F0F8 Cluster: Zinc metalloprotease; n=3; Mollicutes|Rep:
Zinc metalloprotease - Mesoplasma florum (Acholeplasma
florum)
Length = 238
Score = 32.7 bits (71), Expect = 9.7
Identities = 24/84 (28%), Positives = 40/84 (47%), Gaps = 4/84 (4%)
Frame = -1
Query: 370 LADALKVKRVIFVSGKH--YYELHKERVRARLEDVAIVRVEALAPFPLPELQMQLSKYKN 197
L +LK+K+ + G + Y +KE+ L V V APF P+ +++ YKN
Sbjct: 8 LMSSLKIKKTLSYQGNNLSYTITYKEQKHIILR-VIQGEVRISAPFNTPDWEIEKIIYKN 66
Query: 196 ATKFIWSQEEHRNMGAWSF--MKP 131
+K + Q +H + F +KP
Sbjct: 67 ISKIVSVQNKHIIASVYDFNTLKP 90
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 767,435,914
Number of Sequences: 1657284
Number of extensions: 15708773
Number of successful extensions: 51658
Number of sequences better than 10.0: 79
Number of HSP's better than 10.0 without gapping: 48856
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 51442
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 60500186565
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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