Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner10h12f
(628 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p - ... 77 3e-13
UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3; ... 61 2e-08
UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 52 9e-06
UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 52 1e-05
UniRef50_UPI0000DAE34D Cluster: hypothetical protein Rgryl_01000... 51 3e-05
UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 50 3e-05
UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E... 49 1e-04
UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 48 1e-04
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 48 1e-04
UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 47 4e-04
UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 46 6e-04
UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 46 6e-04
UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 46 0.001
UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergil... 45 0.002
UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 44 0.002
UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit, p... 43 0.005
UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 42 0.009
UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 42 0.012
UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 42 0.012
UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1; Opitut... 42 0.012
UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5; Viridipla... 42 0.012
UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 compone... 42 0.012
UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 41 0.021
UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 41 0.021
UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1; ... 41 0.021
UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 41 0.028
UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase (Succinyl-tr... 41 0.028
UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1; ... 41 0.028
UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole gen... 41 0.028
UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1; Dictyo... 41 0.028
UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, who... 41 0.028
UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albica... 40 0.037
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 40 0.049
UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome s... 40 0.065
UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 40 0.065
UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase doma... 39 0.085
UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 38 0.15
UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;... 38 0.15
UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 38 0.20
UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 38 0.20
UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 38 0.26
UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subuni... 37 0.45
UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 37 0.45
UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 36 1.1
UniRef50_Q4HKB1 Cluster: Integrase, phage family VC1758; n=4; Ca... 36 1.1
UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1; ... 35 1.4
UniRef50_Q1Q698 Cluster: Putative uncharacterized protein; n=3; ... 35 1.8
UniRef50_A7GYZ2 Cluster: Putative uncharacterized protein; n=2; ... 34 2.4
UniRef50_A4BAV5 Cluster: Elastase LasB; n=1; Reinekea sp. MED297... 34 2.4
UniRef50_A3DCH5 Cluster: Putative uncharacterized protein; n=1; ... 34 2.4
UniRef50_Q27741 Cluster: Glucose-6-phosphate 1-dehydrogenase; n=... 34 2.4
UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1... 34 3.2
UniRef50_UPI000038E379 Cluster: hypothetical protein Faci_030006... 33 4.2
UniRef50_P43741 Cluster: DNA polymerase I; n=140; Bacteria|Rep: ... 33 4.2
UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 33 5.6
UniRef50_Q4RMD7 Cluster: Chromosome 10 SCAF15019, whole genome s... 33 7.4
UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n... 33 7.4
UniRef50_A0DV60 Cluster: Chromosome undetermined scaffold_65, wh... 33 7.4
UniRef50_Q73LQ8 Cluster: Putative uncharacterized protein; n=1; ... 32 9.8
UniRef50_Q1VY18 Cluster: Coproporphyrinogen III oxidase; n=1; Ps... 32 9.8
UniRef50_Q22WC0 Cluster: Putative uncharacterized protein; n=1; ... 32 9.8
>UniRef50_Q8IGV6 Cluster: RE22749p; n=7; Diptera|Rep: RE22749p -
Drosophila melanogaster (Fruit fly)
Length = 919
Score = 77.0 bits (181), Expect = 3e-13
Identities = 40/118 (33%), Positives = 65/118 (55%), Gaps = 2/118 (1%)
Frame = +1
Query: 277 YHSGAGVFGHRPTIADEYEIPEDIISKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNES 456
YHS GV+G++P E+++ ED+ + R + V A+R +GH A ++ + R
Sbjct: 23 YHSEKGVWGYKPIAQREFQVAEDVRASRNSQANVYRFVEAFRQHGHKLAAVNPISIRTSQ 82
Query: 457 RNIKELHYSRYGLDPEETVDT-GLLYGYSGNNSIKSLVDELVKIYCGH-ISYEFTHLE 624
+ ++EL + YGL +E V T GLL G +++ L L IYCG S EF+++E
Sbjct: 83 QELQELSPAFYGLQTQEPVRTDGLLSGPQVAHNVAQLEQLLKDIYCGRSTSAEFSYVE 140
>UniRef50_Q23629 Cluster: Putative uncharacterized protein; n=3;
Bilateria|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 911
Score = 60.9 bits (141), Expect = 2e-08
Identities = 39/117 (33%), Positives = 60/117 (51%)
Frame = +1
Query: 277 YHSGAGVFGHRPTIADEYEIPEDIISKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNES 456
Y G GVFGH P + E+ +N + L+NA+R YG+L+A +D + R +
Sbjct: 24 YRPGHGVFGHLPD--PPKRVFENQGGLTPENAQRVHLINAFRRYGYLEADLDPLGLR-KV 80
Query: 457 RNIKELHYSRYGLDPEETVDTGLLYGYSGNNSIKSLVDELVKIYCGHISYEFTHLES 627
++ EL + YGL +E V GN S+ L ++L IYCG + EF H+ +
Sbjct: 81 ESVAELDPAIYGLSLDENV--------KGNFSLHDLAEQLRHIYCGPTAIEFMHINN 129
>UniRef50_A5CEI8 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Orientia tsutsugamushi Boryong|Rep:
2-oxoglutarate dehydrogenase, E1 component - Orientia
tsutsugamushi (strain Boryong) (Rickettsia
tsutsugamushi)
Length = 963
Score = 52.4 bits (120), Expect = 9e-06
Identities = 27/90 (30%), Positives = 53/90 (58%), Gaps = 4/90 (4%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDYRNE-SRNIKELHYSRYGL---DPEETVDTGLLY 531
K + QQL+ YR+ GHL A +D ++ + + ++ L + +GL D ++ L
Sbjct: 101 KQLQIQQLIEVYRSNGHLCAKLDPLNLQEQKTKEQAHLSLNYFGLSEFDLDKNFHFTLCN 160
Query: 532 GYSGNNSIKSLVDELVKIYCGHISYEFTHL 621
++ +++++L+ +L +IYCG+I+ EF HL
Sbjct: 161 NFAQVSNLRTLISQLEQIYCGNIAVEFNHL 190
>UniRef50_A7AW62 Cluster: 2-oxoglutarate dehydrogenase E1 component
, putative; n=1; Babesia bovis|Rep: 2-oxoglutarate
dehydrogenase E1 component , putative - Babesia bovis
Length = 891
Score = 52.0 bits (119), Expect = 1e-05
Identities = 33/95 (34%), Positives = 51/95 (53%), Gaps = 12/95 (12%)
Frame = +1
Query: 373 RAQQLVNAYRTYGHLKATIDNVDYRNE--------SRNIKELHYSRYGLDPEE---TVDT 519
R +LV AYRT GH +T+D +D E S +L ++ YGL E+ + +
Sbjct: 23 RLSELVRAYRTEGHCVSTLDPLDLPREPPFHRFIPSDVSTKLCHTTYGLKDEDLGRPLPS 82
Query: 520 GLLYGYSGNNS-IKSLVDELVKIYCGHISYEFTHL 621
GL+ G+ G++S + +D L + YCG + EF HL
Sbjct: 83 GLIPGHMGSSSTVAECIDNLRRTYCGDFAVEFIHL 117
>UniRef50_UPI0000DAE34D Cluster: hypothetical protein
Rgryl_01000074; n=1; Rickettsiella grylli|Rep:
hypothetical protein Rgryl_01000074 - Rickettsiella
grylli
Length = 929
Score = 50.8 bits (116), Expect = 3e-05
Identities = 27/85 (31%), Positives = 47/85 (55%), Gaps = 2/85 (2%)
Frame = +1
Query: 373 RAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSG--N 546
+ Q+L++AYR YGH +A +D + R I +L+ Y + + L G G N
Sbjct: 88 KLQRLIDAYRRYGHYQAHLDPLALA-PKREIVDLNLEHYDISEQALSSIVHLNGLLGLQN 146
Query: 547 NSIKSLVDELVKIYCGHISYEFTHL 621
+++S+++ L KIYC I +E+ H+
Sbjct: 147 VTVESVLNHLKKIYCRSIGFEYEHI 171
>UniRef50_Q057P3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E1 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 933
Score = 50.4 bits (115), Expect = 3e-05
Identities = 24/83 (28%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Frame = +1
Query: 388 VNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEE---TVDTGLLYGYSGNNSIK 558
+N+YR YGH + ++ + R + +I EL YS + + EE + + L+ NS +
Sbjct: 90 INSYRKYGHFISQLNPLKLRKKKNSIPELLYSYHNIKKEELNLLIKSDFLFFKKNINSFQ 149
Query: 559 SLVDELVKIYCGHISYEFTHLES 627
+ K YCG+I +E+ H+ +
Sbjct: 150 DIYLFFKKKYCGYIGFEYMHISN 172
>UniRef50_Q5NYB8 Cluster: 2-oxoglutarate dehydrogenase complex, E1
component; n=7; Bacteria|Rep: 2-oxoglutarate
dehydrogenase complex, E1 component - Azoarcus sp.
(strain EbN1) (Aromatoleum aromaticum (strain EbN1))
Length = 942
Score = 48.8 bits (111), Expect = 1e-04
Identities = 27/84 (32%), Positives = 48/84 (57%), Gaps = 4/84 (4%)
Frame = +1
Query: 382 QLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGL---DPEETVDTGLLYGYSGNN- 549
QL+NAYR G+ A +D + R E + EL S YG D ++ + G +G+S ++
Sbjct: 90 QLINAYRFLGNRWANLDPLK-RTERPQLAELEPSFYGFTEADLNQSFNVGSFHGFSADHA 148
Query: 550 SIKSLVDELVKIYCGHISYEFTHL 621
+++ +++ L + YCG I E+ H+
Sbjct: 149 TLREILEALRQTYCGSIGSEYMHI 172
>UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
E1 component - Haemophilus influenzae
Length = 935
Score = 48.4 bits (110), Expect = 1e-04
Identities = 29/91 (31%), Positives = 47/91 (51%), Gaps = 4/91 (4%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVD-YRNESRNIKELHYSRYGLDPEETVDTGLL--YG 534
K + Q +NAYR GHL+A +D ++ YR + + EL Y +G ++ +T + Y
Sbjct: 88 KLVKVLQFINAYRFRGHLEANLDPLNYYRWKVSFVPELDYRHHGFTEQDLNETFNINHYV 147
Query: 535 YSGNN-SIKSLVDELVKIYCGHISYEFTHLE 624
Y + + L L + YCG I EF H++
Sbjct: 148 YKRDTIKLGELAQMLKETYCGSIGLEFMHVQ 178
>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Brucella melitensis
Length = 1004
Score = 48.4 bits (110), Expect = 1e-04
Identities = 29/99 (29%), Positives = 46/99 (46%), Gaps = 5/99 (5%)
Frame = +1
Query: 340 EDIISKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEE---- 507
E+I + RA ++ AYR GHL A +D + + + EL YG P +
Sbjct: 122 EEITQAARDSVRAIMMIRAYRMRGHLHANLDPLGLAEKPNDYNELEPENYGFTPADYNRK 181
Query: 508 -TVDTGLLYGYSGNNSIKSLVDELVKIYCGHISYEFTHL 621
+D L Y+ ++ ++D L + YCG I EF H+
Sbjct: 182 IFIDNVLGLEYA---TVPEMLDILKRTYCGAIGVEFMHI 217
>UniRef50_P20967 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial precursor; n=34; Fungi/Metazoa group|Rep:
2-oxoglutarate dehydrogenase E1 component, mitochondrial
precursor - Saccharomyces cerevisiae (Baker's yeast)
Length = 1014
Score = 46.8 bits (106), Expect = 4e-04
Identities = 30/98 (30%), Positives = 49/98 (50%), Gaps = 13/98 (13%)
Frame = +1
Query: 373 RAQQLVNAYRTYGHLKATID--NVDYRNESRN-------IKELHYSRYGLDPEETVDTGL 525
+ Q L AY+ GHLKA ID + + + N + +S++ LD E + G+
Sbjct: 124 KVQLLCRAYQVRGHLKAHIDPLGISFGSNKNNPVPPELTLDYYGFSKHDLDKEINLGPGI 183
Query: 526 L--YGYSGNN--SIKSLVDELVKIYCGHISYEFTHLES 627
L + G + S+K +VD L K+YC ++TH+ S
Sbjct: 184 LPRFARDGKSKMSLKEIVDHLEKLYCSSYGVQYTHIPS 221
>UniRef50_Q1R3M6 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=5; Enterobacteriaceae|Rep: 2-oxoglutarate
dehydrogenase E1 component - Escherichia coli (strain
UTI89 / UPEC)
Length = 939
Score = 46.4 bits (105), Expect = 6e-04
Identities = 27/90 (30%), Positives = 49/90 (54%), Gaps = 2/90 (2%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETV-DTGLLYG-Y 537
K QL+NA+RT GHL+A +D + N ++ L +GL E+ + + + +G +
Sbjct: 89 KQAAVIQLINAWRTQGHLRAKLDPLGL-NPPADVPSLQPGFWGLSEEDLLQEFSVTFGAH 147
Query: 538 SGNNSIKSLVDELVKIYCGHISYEFTHLES 627
+ +K L++ L + + G +YE HLE+
Sbjct: 148 TTQMPLKQLLNLLEQAWAGSQAYELAHLEN 177
>UniRef50_A5K5P2 Cluster: 2-oxoglutarate dehydrogenase E1 component,
mitochondrial, putative; n=9; Plasmodium|Rep:
2-oxoglutarate dehydrogenase E1 component,
mitochondrial, putative - Plasmodium vivax
Length = 1059
Score = 46.4 bits (105), Expect = 6e-04
Identities = 32/104 (30%), Positives = 51/104 (49%), Gaps = 17/104 (16%)
Frame = +1
Query: 361 YKNCRAQQLVNAYRTYGHLKATIDNVDYRN--------ESRNIKELHYSRYG-----LDP 501
Y R QL+ Y+ GHL A I+ + N R+ ++ YS +G LD
Sbjct: 122 YDIARIVQLIRWYQKKGHLYANINPLPLPNVPPYSSVVNERDKNKMSYSDFGFTQDDLDA 181
Query: 502 EETVDTGLLYGYSGN----NSIKSLVDELVKIYCGHISYEFTHL 621
E D + G+S N ++++SL+D L + YCG I +E+ H+
Sbjct: 182 EFEFDLPSITGFSSNKKETSTLRSLIDRLEQTYCGTIGFEYMHI 225
>UniRef50_A6GF68 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha-ketoglutarate
decarboxylase - Plesiocystis pacifica SIR-1
Length = 927
Score = 45.6 bits (103), Expect = 0.001
Identities = 28/87 (32%), Positives = 46/87 (52%), Gaps = 4/87 (4%)
Frame = +1
Query: 373 RAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSG--- 543
+ L+ AYR +GH+ A ID + R S + EL + YGL E+ +D +G +G
Sbjct: 71 QVDNLIEAYRLHGHIGADIDPLG-RPRSTDATELDPAHYGLG-EQHMDRE--FGTAGLTP 126
Query: 544 -NNSIKSLVDELVKIYCGHISYEFTHL 621
S++ +++ L YC H+ E+ HL
Sbjct: 127 HKASLREIIERLRNTYCRHVGVEYWHL 153
>UniRef50_Q2UQN4 Cluster: RIB40 genomic DNA, SC005; n=1; Aspergillus
oryzae|Rep: RIB40 genomic DNA, SC005 - Aspergillus
oryzae
Length = 453
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 8/100 (8%)
Frame = +1
Query: 352 SKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNI-KELHYSRYGLDPEE-----TV 513
S K + QL+ AY+ +GH A+ D + NE + KEL S YGL ++ TV
Sbjct: 58 SSTVKQLKVIQLIQAYQRWGHEHASTDPLGMANEGKICRKELQLSHYGLSEQDLDLVLTV 117
Query: 514 DTGLLYGYSGN--NSIKSLVDELVKIYCGHISYEFTHLES 627
TG + ++ + ++ K YC + E+ H+ +
Sbjct: 118 GTGSVQDFTSEKPKPLWEVIAACEKTYCSTMGIEYMHISN 157
>UniRef50_P20707 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=149; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Azotobacter vinelandii
Length = 943
Score = 44.4 bits (100), Expect = 0.002
Identities = 25/88 (28%), Positives = 40/88 (45%), Gaps = 2/88 (2%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDY--RNESRNIKELHYSRYGLDPEETVDTGLLYGY 537
K +L+ AYRT GH + +D + R ++ HY D + TG LY
Sbjct: 92 KQVEVLRLIQAYRTRGHQASQLDPLGLWQRTAPSDLSITHYGLTNADLDTPFRTGELYIG 151
Query: 538 SGNNSIKSLVDELVKIYCGHISYEFTHL 621
+++ ++ L + YC I EFTH+
Sbjct: 152 KEEATLREILQALQETYCRTIGAEFTHI 179
>UniRef50_Q387A7 Cluster: 2-oxoglutarate dehydrogenase subunit,
putative; n=7; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase subunit, putative - Trypanosoma brucei
Length = 1008
Score = 43.2 bits (97), Expect = 0.005
Identities = 27/101 (26%), Positives = 51/101 (50%), Gaps = 14/101 (13%)
Frame = +1
Query: 352 SKRYKNCRAQQLVNAYRTYGHLKATIDNV----DYRNESRNIKELHYSRYGLDPEET--- 510
S+R ++ +V AY YGH A ++ + D ++ R++ LHYS +G ++
Sbjct: 96 SERRQSMGITWMVTAYERYGHHYAKVNPLRSEQDVESDRRDLLNLHYSNFGFTDQDLTKV 155
Query: 511 ----VDTGLLYGYSGN---NSIKSLVDELVKIYCGHISYEF 612
+ GL + N +++ +V++L +YCG I +EF
Sbjct: 156 FPVDIGGGLKEAFGENVKEATLQQIVEKLQMMYCGSIGFEF 196
>UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate
dehydrogenase E1 component - Blochmannia floridanus
Length = 970
Score = 42.3 bits (95), Expect = 0.009
Identities = 25/83 (30%), Positives = 41/83 (49%), Gaps = 3/83 (3%)
Frame = +1
Query: 382 QLVNAYRTYGHLKATID--NVDYRNESRNIKELHYSRY-GLDPEETVDTGLLYGYSGNNS 552
QL++++R YGH + +D + + EL Y ++ D + DT LL G +
Sbjct: 102 QLIHSFRKYGHQYSILDPLGLTINTVKNSFLELKYYKFLDKDVLQQFDTNLLGMNKGIIT 161
Query: 553 IKSLVDELVKIYCGHISYEFTHL 621
+ S+ L K YCG I E+ H+
Sbjct: 162 LNSIYKFLKKTYCGTIGIEYMHI 184
>UniRef50_Q7UM46 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=4;
Bacteria|Rep: Alpha-ketoglutarate dehydrogenase E1 -
Rhodopirellula baltica
Length = 969
Score = 41.9 bits (94), Expect = 0.012
Identities = 29/110 (26%), Positives = 54/110 (49%), Gaps = 3/110 (2%)
Frame = +1
Query: 307 RPTIADEYEIPEDIISKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSR 486
RP + + + + R ++ R QLV YR GHL AT+D + + EL
Sbjct: 101 RPGSTGDQNVDQALWLARIQD-RVDQLVREYRVRGHLVATLDPLGLFEHT--CPELSPRS 157
Query: 487 YGLDPEETV---DTGLLYGYSGNNSIKSLVDELVKIYCGHISYEFTHLES 627
+GL ++ D+ +L SG +++ ++++L YC I +F H+++
Sbjct: 158 HGLSKQDLARPFDSSILENVSG-STLDVILNKLQSTYCRSIGAQFMHIDN 206
>UniRef50_Q12AA2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=12; root|Rep: 2-oxoglutarate dehydrogenase,
E1 component - Polaromonas sp. (strain JS666 / ATCC
BAA-500)
Length = 963
Score = 41.9 bits (94), Expect = 0.012
Identities = 29/88 (32%), Positives = 41/88 (46%), Gaps = 3/88 (3%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGL---DPEETVDTGLLYG 534
K QQL+ AYR G A +D + R E I EL S YG D E +T +
Sbjct: 101 KRTATQQLIAAYRNVGARWADLDPLK-RAERDKIPELEPSFYGFTDADQETVFNTSNTFF 159
Query: 535 YSGNNSIKSLVDELVKIYCGHISYEFTH 618
S++ L++ L + YCG I E+ +
Sbjct: 160 GKDTMSLRELINALRETYCGTIGAEYMY 187
>UniRef50_A7CWX7 Cluster: Oxoglutarate dehydrogenase; n=1;
Opitutaceae bacterium TAV2|Rep: Oxoglutarate
dehydrogenase - Opitutaceae bacterium TAV2
Length = 384
Score = 41.9 bits (94), Expect = 0.012
Identities = 20/90 (22%), Positives = 47/90 (52%), Gaps = 2/90 (2%)
Frame = +1
Query: 361 YKNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYS 540
YK + + +NA+R++GHL+A +D + + +L + +GL ++ + L +
Sbjct: 62 YKQAQVGRFINAHRSHGHLEAHLDPLG--DAPPPHPKLALASFGLTDDDLDEAFTLTNFK 119
Query: 541 GNNS--IKSLVDELVKIYCGHISYEFTHLE 624
G ++ +V+ + YC ++ E+ H++
Sbjct: 120 GGGQMRLRDIVEAVKDTYCSNVGVEYMHVQ 149
>UniRef50_Q01LD8 Cluster: OSIGBa0096P03.7 protein; n=5;
Viridiplantae|Rep: OSIGBa0096P03.7 protein - Oryza
sativa (Rice)
Length = 1016
Score = 41.9 bits (94), Expect = 0.012
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKEL------HYSRYGLDPEETVDTGL 525
++ R LV AY+ GHLKA +D + E R I ++ +S LD E +
Sbjct: 111 ESMRLLLLVRAYQVSGHLKAKLDPLAL--EERPIPDVLDPAFYGFSEADLDREFFLGVWR 168
Query: 526 LYGYSGNN----SIKSLVDELVKIYCGHISYEFTHL 621
+ G+ N +++S+++ L + YCG I YE+ H+
Sbjct: 169 MAGFLSENRPVQTLRSVLERLEQAYCGTIGYEYMHI 204
>UniRef50_Q4MZ92 Cluster: 2-oxoglutarate dehydrogenase e1 component,
putative; n=2; Theileria|Rep: 2-oxoglutarate
dehydrogenase e1 component, putative - Theileria parva
Length = 1030
Score = 41.9 bits (94), Expect = 0.012
Identities = 27/93 (29%), Positives = 53/93 (56%), Gaps = 10/93 (10%)
Frame = +1
Query: 373 RAQQLVNAYRTYGHLKATIDNVDYRNES---RNIK----ELHYSRY-GLDP--EETVDTG 522
+ +L +AYRT+GHL + +D + E RNI +L+ ++Y D ++ + G
Sbjct: 104 KLNELASAYRTFGHLVSNLDPLKLPKEVPFFRNIDGIYDKLNVNKYFNKDDLAKKIPNLG 163
Query: 523 LLYGYSGNNSIKSLVDELVKIYCGHISYEFTHL 621
+ ++ +++ L ++L + YCG+IS+EF H+
Sbjct: 164 IGGVFNMTGTVEELAEKLKERYCGNISFEFGHI 196
>UniRef50_Q9RXM3 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=15; Bacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Deinococcus radiodurans
Length = 956
Score = 41.1 bits (92), Expect = 0.021
Identities = 25/82 (30%), Positives = 41/82 (50%)
Frame = +1
Query: 376 AQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSGNNSI 555
A LV AYR YGH+ A + + R + EL YGL + + +SG ++
Sbjct: 87 AGALVTAYRVYGHISARNNPLKLRGVP-TVPELTPEFYGLSEADLSEQVQDSPFSG--TL 143
Query: 556 KSLVDELVKIYCGHISYEFTHL 621
+ ++ +L YCG I +E+ +L
Sbjct: 144 RDVIAQLQDTYCGAIGFEYNYL 165
>UniRef50_A5EW58 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Dichelobacter nodosus VCS1703A|Rep:
2-oxoglutarate dehydrogenase, E1 component -
Dichelobacter nodosus (strain VCS1703A)
Length = 917
Score = 41.1 bits (92), Expect = 0.021
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Frame = +1
Query: 385 LVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSGNNSIK-- 558
L+ AYR GH A +D + S +I L + +GL + ++G G +++
Sbjct: 79 LIRAYRVRGHRHAHLDPLT-NAPSEDIAALSLAAHGLTAADYATEFAVFGAFGQKTMRLA 137
Query: 559 SLVDELVKIYCGHISYEFTHLE 624
LV L YC HI+ E +H+E
Sbjct: 138 DLVARLKATYCHHIALETSHIE 159
>UniRef50_A6SI56 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 334
Score = 41.1 bits (92), Expect = 0.021
Identities = 31/97 (31%), Positives = 46/97 (47%), Gaps = 14/97 (14%)
Frame = +1
Query: 373 RAQQLVNAYRTYGHLKATIDNVDYRNESRNI-----KEL---HY--SRYGLDPEETVDTG 522
+ Q L AY+ GH KA ID + R E+ KEL HY S LD E ++ G
Sbjct: 145 KVQLLCRAYQARGHHKADIDPLGIRREAEEFGYSKPKELQLEHYQFSEKDLDTEYSLGPG 204
Query: 523 LLYGYSGNNSIKSLVDELV----KIYCGHISYEFTHL 621
+L + + K + E++ +IYCG E+ H+
Sbjct: 205 ILPHFKKSGREKMTLREIIAACERIYCGSYGVEYIHI 241
>UniRef50_Q14JZ4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=11; Francisella tularensis|Rep: 2-oxoglutarate
dehydrogenase E1 component - Francisella tularensis
subsp. tularensis (strain FSC 198)
Length = 941
Score = 40.7 bits (91), Expect = 0.028
Identities = 23/85 (27%), Positives = 46/85 (54%), Gaps = 2/85 (2%)
Frame = +1
Query: 373 RAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSGNNS 552
+A+ LV AYR+YG+ A ID + R+ +L + +GL ++ L ++ N +
Sbjct: 96 KAKALVKAYRSYGYKSANIDPLGLTRFERD-SDLELAAHGLSEKDLTQLVNLGDFTDNKA 154
Query: 553 I--KSLVDELVKIYCGHISYEFTHL 621
I + ++++ IY +I YE+ ++
Sbjct: 155 IPLQQVINKAKAIYESNIGYEYRYI 179
>UniRef50_Q11PR5 Cluster: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component; n=4;
Bacteroidetes|Rep: Oxoglutarate dehydrogenase
(Succinyl-transferring), E1 component - Cytophaga
hutchinsonii (strain ATCC 33406 / NCIMB 9469)
Length = 946
Score = 40.7 bits (91), Expect = 0.028
Identities = 25/87 (28%), Positives = 45/87 (51%), Gaps = 1/87 (1%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKEL-HYSRYGLDPEETVDTGLLYGYS 540
K R L++AYR+ GHL++ + V R + + + EL + D + + G G
Sbjct: 90 KEVRVHYLIHAYRSRGHLRSKTNPVRERKDRKPLLELTDFGLTDADLDVVFEAGNEIGI- 148
Query: 541 GNNSIKSLVDELVKIYCGHISYEFTHL 621
G S++ +V+ L IY G I +E+ ++
Sbjct: 149 GAASLRKIVETLKFIYEGAIGFEYMYI 175
>UniRef50_A7BE99 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 1304
Score = 40.7 bits (91), Expect = 0.028
Identities = 28/90 (31%), Positives = 44/90 (48%), Gaps = 3/90 (3%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGL---DPEETVDTGLLYG 534
K R +L++AYR+ GHL A D + YR R +L S YGL D + TG +G
Sbjct: 436 KPARIAELIHAYRSRGHLAADTDPLAYR--VRRHPDLDLSSYGLSVWDLDRPFPTG-GFG 492
Query: 535 YSGNNSIKSLVDELVKIYCGHISYEFTHLE 624
S ++ ++ L Y + E+ H++
Sbjct: 493 DSDQMLLRDILTRLHDTYTRTVGIEYMHIQ 522
>UniRef50_A7PIZ4 Cluster: Chromosome chr13 scaffold_17, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr13 scaffold_17, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 973
Score = 40.7 bits (91), Expect = 0.028
Identities = 29/96 (30%), Positives = 49/96 (51%), Gaps = 10/96 (10%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKE-LHYSRYG-----LDPEETVDTGL 525
++ R LV AY+ GH+KA +D + E R I + L + YG LD E +
Sbjct: 120 ESMRLLLLVRAYQVNGHMKAKLDPLGL--EEREIPDDLDPALYGFTEADLDREFFLGVWR 177
Query: 526 LYGYSGNN----SIKSLVDELVKIYCGHISYEFTHL 621
+ G+ N ++++++ L + YCG I YE+ H+
Sbjct: 178 MAGFLSENRPVQTLRAILTRLEQAYCGSIGYEYMHI 213
>UniRef50_Q54VG0 Cluster: Oxoglutarate dehydrogenase; n=1;
Dictyostelium discoideum AX4|Rep: Oxoglutarate
dehydrogenase - Dictyostelium discoideum AX4
Length = 900
Score = 40.7 bits (91), Expect = 0.028
Identities = 23/82 (28%), Positives = 41/82 (50%)
Frame = +1
Query: 382 QLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSGNNSIKS 561
+L++ YR +GHL A ID + R E + L RY L +++ + + ++
Sbjct: 38 RLIDGYRAHGHLAANIDPL-ARMERIRSQLLDLDRYNLVKGQSIPSTIDLINQDLTNLDQ 96
Query: 562 LVDELVKIYCGHISYEFTHLES 627
+V L YC ++ +F H+ES
Sbjct: 97 VVSFLENAYCNDVTAQFDHIES 118
>UniRef50_A0DG23 Cluster: Chromosome undetermined scaffold_5, whole
genome shotgun sequence; n=4; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_5,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 1002
Score = 40.7 bits (91), Expect = 0.028
Identities = 32/105 (30%), Positives = 51/105 (48%), Gaps = 20/105 (19%)
Frame = +1
Query: 373 RAQQLVNAYRTYGHLKATIDNVDYRN-----ESRNIKELHYSRY----GLDPE----ETV 513
R + L+N YR GH K+ +D +D + + + +L Y Y LD E + V
Sbjct: 103 RVRLLINKYRHRGHEKSMVDPLDLEHIQQIGKVKGYTKLDYREYFAEEDLDREFYIHDEV 162
Query: 514 DTGLLYGYSGNNSI-------KSLVDELVKIYCGHISYEFTHLES 627
+G+ N+ I + L++ L K YCG ISYE+ H++S
Sbjct: 163 SSGISKEKQCNDLINYVVMKLRDLINYLEKAYCGKISYEYMHIQS 207
>UniRef50_Q6BKY7 Cluster: Similar to CA3149|CaKGD1 Candida albicans
CaKGD1 2-oxoglutarate dehydrogenase; n=4;
Ascomycota|Rep: Similar to CA3149|CaKGD1 Candida
albicans CaKGD1 2-oxoglutarate dehydrogenase -
Debaryomyces hansenii (Yeast) (Torulaspora hansenii)
Length = 997
Score = 40.3 bits (90), Expect = 0.037
Identities = 29/107 (27%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Frame = +1
Query: 340 EDIISKRYKNCRAQQLVNAYRTYGHLKATID--NVDYRNESRNIKELHYSRYG-----LD 498
ED+++ + + Q LV AY+ GH KA ID + + + KEL YG +D
Sbjct: 104 EDVVT----HLKVQLLVRAYQVRGHQKAKIDPLGISFGDNDVVPKELTLEHYGFTEADMD 159
Query: 499 PEETVDTGLL--YGYSGNNS--IKSLVDELVKIYCGHISYEFTHLES 627
+ T+ G+L + G S ++ ++ ++YC E+ H+ S
Sbjct: 160 KQITLGPGILPRFAEGGKKSLTLREIISNCERLYCQSYGVEYIHIPS 206
>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=3; Bacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Salinibacter ruber (strain
DSM 13855)
Length = 1243
Score = 39.9 bits (89), Expect = 0.049
Identities = 30/98 (30%), Positives = 46/98 (46%), Gaps = 3/98 (3%)
Frame = +1
Query: 337 PEDIISKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGL---DPEE 507
P+D + K QL+ AYR GHL+A I+ + Y E + +EL + YGL D +
Sbjct: 374 PQDELDMTEKQAAVLQLIRAYRVRGHLQADINPLGY--EWQYHEELDPATYGLTVWDLDR 431
Query: 508 TVDTGLLYGYSGNNSIKSLVDELVKIYCGHISYEFTHL 621
TG L G ++ ++ L K Y + F H+
Sbjct: 432 EFITGGL-GGEDKLPLREILSILRKSYTSKVGTAFMHI 468
>UniRef50_Q4RSE1 Cluster: Chromosome 13 SCAF15000, whole genome
shotgun sequence; n=1; Tetraodon nigroviridis|Rep:
Chromosome 13 SCAF15000, whole genome shotgun sequence -
Tetraodon nigroviridis (Green puffer)
Length = 974
Score = 39.5 bits (88), Expect = 0.065
Identities = 18/52 (34%), Positives = 32/52 (61%)
Frame = +1
Query: 277 YHSGAGVFGHRPTIADEYEIPEDIISKRYKNCRAQQLVNAYRTYGHLKATID 432
YH+ GV+G+RP +D P+ ++ +++ ++LV AYR +GH A I+
Sbjct: 27 YHTEKGVYGYRPKKSDS---PQRLVMAPHQDHGLERLVQAYRAHGHKAAKIN 75
>UniRef50_A7H8J4 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Anaeromyxobacter|Rep: 2-oxoglutarate dehydrogenase,
E1 subunit - Anaeromyxobacter sp. Fw109-5
Length = 940
Score = 39.5 bits (88), Expect = 0.065
Identities = 23/83 (27%), Positives = 39/83 (46%)
Frame = +1
Query: 373 RAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSGNNS 552
+ +LV AYR YGHL+A +D + +R + + +GL E G+ +
Sbjct: 86 KVDRLVTAYREYGHLRADLDPLAL---TRRAERFSPATFGLSDAELERPCADPEGRGDRT 142
Query: 553 IKSLVDELVKIYCGHISYEFTHL 621
++ LV L + YC + E H+
Sbjct: 143 LRGLVARLEETYCRTLGVELAHM 165
>UniRef50_Q96HY7 Cluster: Dehydrogenase E1 and transketolase
domain-containing protein 1; n=39; Eumetazoa|Rep:
Dehydrogenase E1 and transketolase domain-containing
protein 1 - Homo sapiens (Human)
Length = 919
Score = 39.1 bits (87), Expect = 0.085
Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 3/120 (2%)
Frame = +1
Query: 277 YHSGAGVFGHRPTIADEYEIPEDIISKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNES 456
Y + GV+G+RP + E P+ + + + +LV Y +GH A I+ + + ++
Sbjct: 24 YQTERGVYGYRPRKPESRE-PQGALERPPVDHGLARLVTVYCEHGHKAAKINPL-FTGQA 81
Query: 457 --RNIKELHYSRYGLD-PEETVDTGLLYGYSGNNSIKSLVDELVKIYCGHISYEFTHLES 627
N+ E+ L P T GLL S++ ++ L +IYCG IS E + L+S
Sbjct: 82 LLENVPEIQALVQTLQGPFHTA--GLLNMGKEEASLEEVLVYLNQIYCGQISIETSQLQS 139
>UniRef50_Q3JEV2 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=2; Proteobacteria|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Nitrosococcus oceani
(strain ATCC 19707 / NCIMB 11848)
Length = 940
Score = 38.3 bits (85), Expect = 0.15
Identities = 28/89 (31%), Positives = 41/89 (46%), Gaps = 3/89 (3%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEE---TVDTGLLYG 534
K QL+NAYR GH KA ID + + + +L +GL E+ TG L G
Sbjct: 88 KQIAVLQLINAYRFRGHQKANIDPLRIYDRP-VVSDLDPVFHGLTEEDMGKVFSTGSLIG 146
Query: 535 YSGNNSIKSLVDELVKIYCGHISYEFTHL 621
++ + + KIYC I E+ H+
Sbjct: 147 ID-QAPLEEIFALIKKIYCHTIGAEYMHI 174
>UniRef50_A6DL94 Cluster: Alpha-ketoglutarate decarboxylase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Alpha-ketoglutarate
decarboxylase - Lentisphaera araneosa HTCC2155
Length = 913
Score = 38.3 bits (85), Expect = 0.15
Identities = 27/91 (29%), Positives = 42/91 (46%), Gaps = 3/91 (3%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDP---EETVDTGLLYG 534
K + +L+NAYR+ GHL + + + R + L Y +GLD EE D G
Sbjct: 58 KEVKIMKLINAYRSRGHLISKTNPIRPRRLHQADLTLDY--FGLDEADLEEEFDVGHEIR 115
Query: 535 YSGNNSIKSLVDELVKIYCGHISYEFTHLES 627
G +K ++ L YC I E+ + +S
Sbjct: 116 L-GRAKLKDIISHLEDTYCSSIGVEYRYSQS 145
>UniRef50_Q2GDI7 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=1; Neorickettsia sennetsu str.
Miyayama|Rep: 2-oxoglutarate dehydrogenase, E1 component
- Neorickettsia sennetsu (strain Miyayama)
Length = 905
Score = 37.9 bits (84), Expect = 0.20
Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 1/101 (0%)
Frame = +1
Query: 322 DEYEIPEDIISKR-YKNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLD 498
D + E+ +S++ + + + L +AYR +G+L A +D + EL+ +GL
Sbjct: 60 DNGAVRENAVSEQSLLDIKIKDLKDAYRRFGYLAADLDLLGLVKPIVR-PELNPEFHGLS 118
Query: 499 PEETVDTGLLYGYSGNNSIKSLVDELVKIYCGHISYEFTHL 621
D L G++ ++ +V E+ +YCGHI +F HL
Sbjct: 119 -----DVSLSSGFT----VEQIVCEMHAVYCGHIGVQFMHL 150
>UniRef50_Q7WRM3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=17; Staphylococcus|Rep: 2-oxoglutarate dehydrogenase
E1 component - Staphylococcus aureus
Length = 932
Score = 37.9 bits (84), Expect = 0.20
Identities = 24/90 (26%), Positives = 51/90 (56%), Gaps = 5/90 (5%)
Frame = +1
Query: 373 RAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPE--ETVDTGLLYGYSG- 543
R +L++ R YGHLKA I V+ + +++ +L + LD + E + G++ +
Sbjct: 71 RVMRLIDNIRQYGHLKADIYPVN-PPKRKHVPKLEIEDFDLDQQTLEGISAGIVSDHFAD 129
Query: 544 --NNSIKSLVDELVKIYCGHISYEFTHLES 627
+N+ ++++ + K Y G I++E+TH+ +
Sbjct: 130 IYDNAYEAIL-RMEKRYKGPIAFEYTHINN 158
>UniRef50_Q8F6S7 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=4; Leptospira|Rep: 2-oxoglutarate dehydrogenase E1
component - Leptospira interrogans
Length = 920
Score = 37.5 bits (83), Expect = 0.26
Identities = 23/79 (29%), Positives = 38/79 (48%)
Frame = +1
Query: 385 LVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSGNNSIKSL 564
L+NAYR GHL A +D + + +R + + + P + +DT + G + +
Sbjct: 82 LLNAYRRQGHLAAKLDPLGIQKPNRTF--IDSKLHNISPAD-IDTVVDSETLGRVKLAEI 138
Query: 565 VDELVKIYCGHISYEFTHL 621
VD K+YC I E +L
Sbjct: 139 VDLYEKVYCNTIGAEHFYL 157
>UniRef50_Q01VQ8 Cluster: 2-oxoglutarate dehydrogenase, E1 subunit;
n=2; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
subunit - Solibacter usitatus (strain Ellin6076)
Length = 1220
Score = 36.7 bits (81), Expect = 0.45
Identities = 30/90 (33%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Frame = +1
Query: 382 QLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGL---DPEETVDTGLLYGYSGNNS 552
Q++NAYR GHL A +D + +E EL YGL D + TG L G +
Sbjct: 350 QMINAYRVRGHLIADLDPLG--SEPSLHAELDPETYGLTIWDLDREFLTGSLGEAIGEGA 407
Query: 553 IKSL------VDELVKIYCGHISYEFTHLE 624
KSL ++ L + YCG I E+ +++
Sbjct: 408 PKSLATLREILETLRQTYCGKIGCEYMNIQ 437
>UniRef50_P51056 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=11; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
E1 component - Coxiella burnetii
Length = 934
Score = 36.7 bits (81), Expect = 0.45
Identities = 25/79 (31%), Positives = 40/79 (50%), Gaps = 2/79 (2%)
Frame = +1
Query: 385 LVNAYRTYGHLKATIDNV-DYRNESRNIKELHYSRYGLDPEETVDT-GLLYGYSGNNSIK 558
L+ YR +GHL A I+ + D R ++ HY+ D +T T GLL ++K
Sbjct: 93 LIEGYRRFGHLNAKINPLGDNRPVDSRLELGHYNLTESDFNKTFATYGLL--NKPKATLK 150
Query: 559 SLVDELVKIYCGHISYEFT 615
+ L +IYCG I +++
Sbjct: 151 EIYTRLREIYCGSIGVQYS 169
>UniRef50_Q5PB66 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=13; Rickettsiales|Rep: 2-oxoglutarate dehydrogenase E1
component - Anaplasma marginale (strain St. Maries)
Length = 930
Score = 35.5 bits (78), Expect = 1.1
Identities = 22/81 (27%), Positives = 38/81 (46%)
Frame = +1
Query: 385 LVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSGNNSIKSL 564
L++ +R+YGHL A +D + + L + ++ + G S+ S+
Sbjct: 101 LLHFFRSYGHLAADLDPLGMAGKVA----LDHDKF---IASIIGDGEAAWRGSGASLPSI 153
Query: 565 VDELVKIYCGHISYEFTHLES 627
+ L + YCG I YEF H+ S
Sbjct: 154 LQALKETYCGSIGYEFMHIPS 174
>UniRef50_Q4HKB1 Cluster: Integrase, phage family VC1758; n=4;
Campylobacter|Rep: Integrase, phage family VC1758 -
Campylobacter lari RM2100
Length = 392
Score = 35.5 bits (78), Expect = 1.1
Identities = 21/57 (36%), Positives = 31/57 (54%), Gaps = 7/57 (12%)
Frame = +1
Query: 304 HRPTIADEYEIPEDI-------ISKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNE 453
H+PT+ DE +I E I I + +KN L+ A R +KAT D +D++NE
Sbjct: 198 HQPTLLDESDIKEYINTLIHSDIKQSHKNLMLFVLLTAQRPGNVIKATWDEIDFKNE 254
>UniRef50_Q54JE4 Cluster: Putative uncharacterized protein; n=1;
Dictyostelium discoideum AX4|Rep: Putative
uncharacterized protein - Dictyostelium discoideum AX4
Length = 1013
Score = 35.1 bits (77), Expect = 1.4
Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 8/88 (9%)
Frame = +1
Query: 385 LVNAYRTYGHLKATID--NVDYRNESRNIKELHY--SRYGLDPEETVDTGLLYGYSGNN- 549
LV AY+ GH A +D ++ + E Y + +D V G + G+ N
Sbjct: 129 LVRAYQVRGHALANLDPLGLEVKEEPAEFNPAKYGFTEADMDRPIFVGEGFISGFLTNKQ 188
Query: 550 ---SIKSLVDELVKIYCGHISYEFTHLE 624
+++ ++ L + YCG I E+ H++
Sbjct: 189 PETTLRQVLKRLKETYCGDIGIEYMHIQ 216
>UniRef50_Q1Q698 Cluster: Putative uncharacterized protein; n=3;
Bacteria|Rep: Putative uncharacterized protein -
Candidatus Kuenenia stuttgartiensis
Length = 272
Score = 34.7 bits (76), Expect = 1.8
Identities = 18/53 (33%), Positives = 29/53 (54%)
Frame = +1
Query: 304 HRPTIADEYEIPEDIISKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNESRN 462
H TIA +PED + K +N + +L+N ++ G+ T+D YR+ S N
Sbjct: 216 HHDTIARIEILPEDFL-KLLQNGKRTELINTFKEIGYKYVTLDVEGYRSGSMN 267
>UniRef50_A7GYZ2 Cluster: Putative uncharacterized protein; n=2;
Campylobacter|Rep: Putative uncharacterized protein -
Campylobacter curvus 525.92
Length = 374
Score = 34.3 bits (75), Expect = 2.4
Identities = 26/101 (25%), Positives = 50/101 (49%), Gaps = 3/101 (2%)
Frame = +1
Query: 232 SRLRCKVDRLYDRVLYHSGAGVFGHRPTIADEYEIPE---DIISKRYKNCRAQQLVNAYR 402
S L+C V L +V+ H G+FG A +PE + +++KN + +Q N ++
Sbjct: 17 SELKCSVTELDIKVIQHPSGGIFGFFKKSAIIEAVPEKQTQKLQEKFKN-KHEQKQNNHK 75
Query: 403 TYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGL 525
+N D +NESR+ + S++ ++V++G+
Sbjct: 76 ---------NNTDNKNESRHTNGNNSSKHDEQEAKSVNSGV 107
>UniRef50_A4BAV5 Cluster: Elastase LasB; n=1; Reinekea sp.
MED297|Rep: Elastase LasB - Reinekea sp. MED297
Length = 1408
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/71 (25%), Positives = 32/71 (45%)
Frame = +1
Query: 340 EDIISKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDT 519
ED+ ++ Y N +R Y H K+ +++V YR + HY + +E +
Sbjct: 279 EDLPTEPYTFDCTDNTTNTHRPYNHAKSPLNDVHYRGQMTTEMYRHYLGHSPYYDEPIRQ 338
Query: 520 GLLYGYSGNNS 552
+ YGY N+
Sbjct: 339 YVHYGYYVGNA 349
>UniRef50_A3DCH5 Cluster: Putative uncharacterized protein; n=1;
Clostridium thermocellum ATCC 27405|Rep: Putative
uncharacterized protein - Clostridium thermocellum
(strain ATCC 27405 / DSM 1237)
Length = 85
Score = 34.3 bits (75), Expect = 2.4
Identities = 19/50 (38%), Positives = 24/50 (48%)
Frame = +1
Query: 367 NCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVD 516
+C +L +AY + H+ V N EL YS YG DPE TVD
Sbjct: 36 HCMPMKLAHAYVPFQHMSCIFPPVKGLNAGTIFPEL-YSPYGKDPEYTVD 84
>UniRef50_Q27741 Cluster: Glucose-6-phosphate 1-dehydrogenase; n=4;
Plasmodium|Rep: Glucose-6-phosphate 1-dehydrogenase -
Plasmodium falciparum
Length = 910
Score = 34.3 bits (75), Expect = 2.4
Identities = 18/70 (25%), Positives = 39/70 (55%), Gaps = 6/70 (8%)
Frame = +1
Query: 406 YGHLKATIDNVDYRNESRNIKELHYSRYGLD------PEETVDTGLLYGYSGNNSIKSLV 567
Y + T+ + Y N +++I+E++ S+Y L +E + T +++G SG+ + K +
Sbjct: 297 YCYSNTTVISCGYENYTKSIEEIYDSKYALSLYSNSLNKEELLTIIIFGCSGDLAKKKIY 356
Query: 568 DELVKIYCGH 597
L K++C +
Sbjct: 357 PALFKLFCNN 366
>UniRef50_UPI00006CD2E0 Cluster: 2-oxoglutarate dehydrogenase, E1
component family protein; n=1; Tetrahymena thermophila
SB210|Rep: 2-oxoglutarate dehydrogenase, E1 component
family protein - Tetrahymena thermophila SB210
Length = 1054
Score = 33.9 bits (74), Expect = 3.2
Identities = 15/50 (30%), Positives = 28/50 (56%), Gaps = 5/50 (10%)
Frame = +1
Query: 493 LDPEETVDTGLLYGYSGNNS-----IKSLVDELVKIYCGHISYEFTHLES 627
LD E ++ G + G + N S ++ L+D L +IYC + Y++ H+ +
Sbjct: 204 LDKEVFINDGRVDGITNNPSKSTWKLRDLIDHLKQIYCNKVGYQYMHINN 253
>UniRef50_UPI000038E379 Cluster: hypothetical protein Faci_03000637;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000637 - Ferroplasma acidarmanus fer1
Length = 229
Score = 33.5 bits (73), Expect = 4.2
Identities = 16/35 (45%), Positives = 21/35 (60%)
Frame = +1
Query: 427 IDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLY 531
I NVD + N+K++ SRYG+ P ETV G Y
Sbjct: 146 IKNVDPAKKDTNVKDIQ-SRYGISPAETVSVGDSY 179
>UniRef50_P43741 Cluster: DNA polymerase I; n=140; Bacteria|Rep: DNA
polymerase I - Haemophilus influenzae
Length = 930
Score = 33.5 bits (73), Expect = 4.2
Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 2/71 (2%)
Frame = +1
Query: 415 LKATIDNVDYRNESRNIK--ELHYSRYGLDPEETVDTGLLYGYSGNNSIKSLVDELVKIY 588
+K ++N + +NIK E ++R+G++ + +L Y+ N++ + +D+L K Y
Sbjct: 409 IKPILENPNIHKIGQNIKFDESIFARHGIELQGVEFDTMLLSYTLNSTGRHNMDDLAKRY 468
Query: 589 CGHISYEFTHL 621
GH + F L
Sbjct: 469 LGHETIAFESL 479
>UniRef50_Q8NRC3 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=45; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Corynebacterium glutamicum (Brevibacterium
flavum)
Length = 1257
Score = 33.1 bits (72), Expect = 5.6
Identities = 23/92 (25%), Positives = 43/92 (46%), Gaps = 6/92 (6%)
Frame = +1
Query: 364 KNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNI---KELHYSRYGL---DPEETVDTGL 525
KN R QL+ AYR+ GHL A + + + + ++L + L D + T + G
Sbjct: 404 KNTRVMQLIEAYRSRGHLIADTNPLSWVQPGMPVPDHRDLDIETHNLTIWDLDRTFNVG- 462
Query: 526 LYGYSGNNSIKSLVDELVKIYCGHISYEFTHL 621
+G +++ ++ L Y + E+TH+
Sbjct: 463 GFGGKETMTLREVLSRLRAAYTLKVGSEYTHI 494
>UniRef50_Q4RMD7 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=2; Tetraodontidae|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 426
Score = 32.7 bits (71), Expect = 7.4
Identities = 17/52 (32%), Positives = 29/52 (55%)
Frame = +1
Query: 238 LRCKVDRLYDRVLYHSGAGVFGHRPTIADEYEIPEDIISKRYKNCRAQQLVN 393
+R + +YD ++ S + G R ++++Y I +D I K YK C+ LVN
Sbjct: 342 VRSGSEEVYDALML-STPTLSGFREAVSEKYGIHKDTIGKIYKRCKRGILVN 392
>UniRef50_A3ZXH0 Cluster: Alpha-ketoglutarate dehydrogenase E1; n=1;
Blastopirellula marina DSM 3645|Rep: Alpha-ketoglutarate
dehydrogenase E1 - Blastopirellula marina DSM 3645
Length = 929
Score = 32.7 bits (71), Expect = 7.4
Identities = 16/84 (19%), Positives = 39/84 (46%), Gaps = 3/84 (3%)
Frame = +1
Query: 382 QLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSGNN---S 552
+++ A+R YGHL + +D + L ++ + E +D + G +
Sbjct: 86 RMITAFRAYGHLHSRLDPLGLTTTPA--PPLSPDQFNIK-ESDLDRSVYVDRDGETILTT 142
Query: 553 IKSLVDELVKIYCGHISYEFTHLE 624
++ L + + ++YCG + + H++
Sbjct: 143 VRELFERMQRVYCGDVGIQLQHID 166
>UniRef50_A0DV60 Cluster: Chromosome undetermined scaffold_65, whole
genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_65,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 385
Score = 32.7 bits (71), Expect = 7.4
Identities = 15/54 (27%), Positives = 33/54 (61%), Gaps = 4/54 (7%)
Frame = +1
Query: 322 DEYEIP-EDIISKRYKNCRAQQLVNAYRTYGHLKATID---NVDYRNESRNIKE 471
DE E+ +D +SK+YKN + ++++ +Y+ HL ++ NV R +++ + +
Sbjct: 237 DEDEVENDDCVSKQYKNAKEKKMLKSYKKVEHLSRVMEHLRNVQNRKKTKVVNK 290
>UniRef50_Q73LQ8 Cluster: Putative uncharacterized protein; n=1;
Treponema denticola|Rep: Putative uncharacterized
protein - Treponema denticola
Length = 848
Score = 32.3 bits (70), Expect = 9.8
Identities = 20/60 (33%), Positives = 30/60 (50%)
Frame = +1
Query: 334 IPEDIISKRYKNCRAQQLVNAYRTYGHLKATIDNVDYRNESRNIKELHYSRYGLDPEETV 513
I + ISK YK Q+V+ +R Y H D D+R+ S NI + S + L E+ +
Sbjct: 706 IYNEFISKLYKAAGLVQIVSEFRLYEH---DSDLNDFRDNSENIIKTIESTFNLTDEKAI 762
>UniRef50_Q1VY18 Cluster: Coproporphyrinogen III oxidase; n=1;
Psychroflexus torquis ATCC 700755|Rep:
Coproporphyrinogen III oxidase - Psychroflexus torquis
ATCC 700755
Length = 300
Score = 32.3 bits (70), Expect = 9.8
Identities = 18/61 (29%), Positives = 31/61 (50%)
Frame = +1
Query: 436 VDYRNESRNIKELHYSRYGLDPEETVDTGLLYGYSGNNSIKSLVDELVKIYCGHISYEFT 615
+DY E RN +E+ RY ++ D G L+G N I+S++ L H+ +++
Sbjct: 223 LDYTKEQRNWQEIRRGRY-VEFNLVHDKGTLFGLKTNGRIESILMSLPP----HVQWQYN 277
Query: 616 H 618
H
Sbjct: 278 H 278
>UniRef50_Q22WC0 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 297
Score = 32.3 bits (70), Expect = 9.8
Identities = 12/34 (35%), Positives = 22/34 (64%)
Frame = -2
Query: 231 HSHFTKTQHTVSFT*YYYNNFYELHQNSTYVSFK 130
+ H+TK +T F +Y +FY+L++NS +F+
Sbjct: 178 YQHYTKIHYTALFLKHYETDFYKLNRNSKISAFE 211
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 579,324,161
Number of Sequences: 1657284
Number of extensions: 11052436
Number of successful extensions: 29063
Number of sequences better than 10.0: 61
Number of HSP's better than 10.0 without gapping: 28173
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 29029
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 46051731393
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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