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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fner10e17f
         (585 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon nigrovi...   159   3e-38
UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate k...   148   8e-35
UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167; Fu...   143   2e-33
UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|R...   109   5e-23
UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P...   103   4e-21
UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=6...   103   4e-21
UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep: ...   101   1e-20
UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep: P...   100   5e-20
UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Re...    98   1e-19
UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep...    98   1e-19
UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania brazil...    97   2e-19
UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep: Py...    97   3e-19
UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular organis...    92   1e-17
UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3; Piropla...    91   2e-17
UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...    90   3e-17
UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep: ...    89   7e-17
UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate k...    89   9e-17
UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep...    89   9e-17
UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3; Ol...    88   1e-16
UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep: P...    85   1e-15
UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio bact...    85   2e-15
UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma japon...    85   2e-15
UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep...    84   2e-15
UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella aerof...    83   6e-15
UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella auran...    82   8e-15
UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep: P...    82   8e-15
UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|R...    82   1e-14
UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta proteobacte...    81   1e-14
UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2; Cystobacterineae|...    81   1e-14
UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Re...    80   3e-14
UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=...    79   6e-14
UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas ac...    79   6e-14
UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter ...    78   1e-13
UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1; ...    78   1e-13
UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast ...    77   3e-13
UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus Protoc...    77   4e-13
UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3; Flexibacteraceae|...    77   4e-13
UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular organism...    77   4e-13
UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular organis...    76   5e-13
UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oce...    76   5e-13
UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon c...    76   7e-13
UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep: Pyr...    75   9e-13
UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n...    75   1e-12
UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep: Pyr...    75   1e-12
UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Re...    75   1e-12
UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3; Methanosarcinacea...    74   2e-12
UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|R...    74   3e-12
UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate k...    73   4e-12
UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae bacte...    73   4e-12
UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep: P...    72   9e-12
UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter rube...    72   9e-12
UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|R...    72   1e-11
UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep: Py...    71   2e-11
UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast ...    71   2e-11
UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep: ...    71   3e-11
UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|R...    71   3e-11
UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca wicker...    70   4e-11
UniRef50_A7D456 Cluster: Pyruvate kinase; n=2; Halobacteriaceae|...    70   4e-11
UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep: Pyr...    69   6e-11
UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep: P...    69   8e-11
UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep: ...    69   8e-11
UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...    69   1e-10
UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter xylan...    69   1e-10
UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya bisexualis...    69   1e-10
UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep...    68   1e-10
UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Re...    68   2e-10
UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria (...    67   2e-10
UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep...    66   4e-10
UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6; Desulfuromonadale...    66   4e-10
UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis...    66   4e-10
UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Re...    66   4e-10
UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130; Proteoba...    66   6e-10
UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp....    66   8e-10
UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep: Py...    66   8e-10
UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus ...    65   1e-09
UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus Phytop...    65   1e-09
UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4; Halobacteriaceae|...    65   1e-09
UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23; Actinobacteridae...    65   1e-09
UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptun...    65   1e-09
UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2; Epsilonproteobact...    65   1e-09
UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular organis...    64   2e-09
UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea psyc...    64   2e-09
UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma citri...    64   2e-09
UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta ...    64   3e-09
UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Re...    64   3e-09
UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum pernix|...    64   3e-09
UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces mari...    63   5e-09
UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis paci...    62   9e-09
UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera aran...    62   9e-09
UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum ...    62   9e-09
UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium sme...    62   1e-08
UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Re...    62   1e-08
UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia pickett...    60   3e-08
UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep: ...    60   4e-08
UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2; Nitrosomonadaceae...    60   5e-08
UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular organism...    60   5e-08
UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|R...    59   7e-08
UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter...    58   2e-07
UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep: P...    58   2e-07
UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173; Proteobacter...    58   2e-07
UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp. ...    57   3e-07
UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4; Desulfovibrionace...    57   3e-07
UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus Desulf...    56   6e-07
UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia A...    56   8e-07
UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep: Pyr...    54   2e-06
UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Re...    54   2e-06
UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole geno...    54   2e-06
UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2; Thermoplasmatales...    52   8e-06
UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep: P...    52   8e-06
UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia persep...    52   1e-05
UniRef50_Q07637 Cluster: Pyruvate kinase; n=44; Streptococcaceae...    52   1e-05
UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,...    52   1e-05
UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|R...    52   1e-05
UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11; Xanthomonadaceae...    50   3e-05
UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus m...    50   3e-05
UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|R...    50   3e-05
UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula m...    50   5e-05
UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:...    50   5e-05
UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma penetr...    48   2e-04
UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella pne...    48   2e-04
UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1; Ba...    48   2e-04
UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus buty...    48   2e-04
UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:...    48   2e-04
UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular organism...    48   2e-04
UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|R...    47   4e-04
UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep: ...    46   9e-04
UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein; ...    45   0.001
UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep...    45   0.002
UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales ...    44   0.004
UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171, w...    44   0.004
UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole geno...    43   0.005
UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium beije...    43   0.006
UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pende...    42   0.008
UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep: ...    42   0.011
UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter aqua...    42   0.014
UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep: Pyr...    41   0.025
UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter vinel...    41   0.025
UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep: Py...    40   0.033
UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutz...    40   0.043
UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter viola...    38   0.13 
UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis thali...    37   0.30 
UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma parvum...    36   0.93 
UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep...    36   0.93 
UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor, ...    35   1.2  
UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vaden...    35   1.6  
UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding...    34   2.2  
UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus ten...    33   3.8  
UniRef50_A5BAI3 Cluster: Putative uncharacterized protein; n=2; ...    33   5.0  
UniRef50_Q1DYT2 Cluster: Putative uncharacterized protein; n=1; ...    33   5.0  
UniRef50_Q8D170 Cluster: UPF0255 protein YPO3224/y0964/YP_0709; ...    33   5.0  
UniRef50_Q470K0 Cluster: RND efflux system, outer membrane lipop...    32   8.7  
UniRef50_A3QC46 Cluster: Sulfotransferase; n=1; Shewanella loihi...    32   8.7  
UniRef50_Q940A6 Cluster: Putative uncharacterized protein At4g19...    32   8.7  

>UniRef50_Q4SVB7 Cluster: Pyruvate kinase; n=1; Tetraodon
           nigroviridis|Rep: Pyruvate kinase - Tetraodon
           nigroviridis (Green puffer)
          Length = 569

 Score =  159 bits (387), Expect = 3e-38
 Identities = 75/122 (61%), Positives = 95/122 (77%)
 Frame = +1

Query: 220 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 399
           L+HMC LDIDS  +  R +GIICTIGPASR+V +L++M+++GMN+AR+NFSHG+HEYHAE
Sbjct: 25  LEHMCLLDIDSAPTTARNTGIICTIGPASRSVGMLKEMIKSGMNIARLNFSHGTHEYHAE 84

Query: 400 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 579
           TI+N REA +S+         + IALDTKGPEIRTGL+ G G+AEVELKKG  IK+T   
Sbjct: 85  TIKNVREACESFEPGSIQYRPIGIALDTKGPEIRTGLIHGSGTAEVELKKGNVIKITLDD 144

Query: 580 DY 585
            Y
Sbjct: 145 AY 146


>UniRef50_UPI0000D5551D Cluster: PREDICTED: similar to Pyruvate
           kinase (PK); n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to Pyruvate kinase (PK) - Tribolium castaneum
          Length = 557

 Score =  148 bits (359), Expect = 8e-35
 Identities = 69/124 (55%), Positives = 91/124 (73%)
 Frame = +1

Query: 214 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 393
           +QL H   LDI S    +RL+GIICT+GP++ +V  LE+M+E GMN+AR+  SHG+ E H
Sbjct: 32  TQLDHNSLLDIQSHPPQVRLTGIICTLGPSTTDVETLERMIEAGMNIARLTLSHGTQEMH 91

Query: 394 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
            E I+N R A ++YS +LG  + L++ALD KGPE+RTG +EGG +AEVELKKGE IKLTT
Sbjct: 92  TELIQNVRTAVENYSKRLGVMYPLSLALDIKGPEVRTGYMEGGIAAEVELKKGEQIKLTT 151

Query: 574 SSDY 585
              Y
Sbjct: 152 DKAY 155


>UniRef50_P30613 Cluster: Pyruvate kinase isozymes R/L; n=167;
           Fungi/Metazoa group|Rep: Pyruvate kinase isozymes R/L -
           Homo sapiens (Human)
          Length = 574

 Score =  143 bits (347), Expect = 2e-33
 Identities = 72/120 (60%), Positives = 93/120 (77%), Gaps = 3/120 (2%)
 Frame = +1

Query: 220 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 399
           L+H+C LDIDS+    R + II TIGPASR+V  L++M++ GMN+AR+NFSHGSHEYHAE
Sbjct: 70  LEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAE 129

Query: 400 TIRNCREAEKSYSAKLGSPFS---LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
           +I N REA +S++   GSP S   +AIALDTKGPEIRTG+L+GG  +EVEL KG  + +T
Sbjct: 130 SIANVREAVESFA---GSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186


>UniRef50_Q27686 Cluster: Pyruvate kinase; n=16; Kinetoplastida|Rep:
           Pyruvate kinase - Leishmania mexicana
          Length = 499

 Score =  109 bits (262), Expect = 5e-23
 Identities = 60/120 (50%), Positives = 82/120 (68%)
 Frame = +1

Query: 214 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 393
           SQL H   L I    +  R + IICTIGP++++V  L+ ++++GM+VARMNFSHGSHEYH
Sbjct: 2   SQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYH 61

Query: 394 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
             TI N R+A    +A+LG   ++AIALDTKGPEIRTG   GG   +  +++G T  +TT
Sbjct: 62  QTTINNVRQA----AAELG--VNIAIALDTKGPEIRTGQFVGG---DAVMERGATCYVTT 112


>UniRef50_Q9VQH0 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 554

 Score =  103 bits (246), Expect = 4e-21
 Identities = 52/131 (39%), Positives = 82/131 (62%)
 Frame = +1

Query: 190 KPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNF 369
           K  +    +QL H+C LD+  ++S+ RL  +I TI  +SRN   +  M+  G+N+ R+NF
Sbjct: 6   KSVLKEGSTQLSHICELDLAQQASHQRLVSLIATISVSSRNADTIYTMIMRGVNIFRLNF 65

Query: 370 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKK 549
           SH SHE H++TI    EA +    + G   ++AIA DT+GP+IRTGLL+G    +V L+ 
Sbjct: 66  SHESHEMHSKTIELINEALERIHKETGQIRTVAIAADTRGPQIRTGLLDG----DVFLRS 121

Query: 550 GETIKLTTSSD 582
           G+ ++L+ + D
Sbjct: 122 GDNLRLSINRD 132


>UniRef50_Q42806 Cluster: Pyruvate kinase, cytosolic isozyme; n=62;
           Eukaryota|Rep: Pyruvate kinase, cytosolic isozyme -
           Glycine max (Soybean)
          Length = 511

 Score =  103 bits (246), Expect = 4e-21
 Identities = 49/101 (48%), Positives = 69/101 (68%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CT+GPASR+V + EK++  GMNVAR NFSHG+H+YH ET+ N +      +A   +  
Sbjct: 25  IVCTLGPASRSVEMTEKLLRAGMNVARFNFSHGTHDYHQETLNNLK------TAMHNTGI 78

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
             A+ LDTKGPEIRTG L+ G    ++LK+G+ + +TT  D
Sbjct: 79  LCAVMLDTKGPEIRTGFLKDG--KPIQLKEGQEVTITTDYD 117


>UniRef50_Q7RVA8 Cluster: Pyruvate kinase; n=11; Ascomycota|Rep:
           Pyruvate kinase - Neurospora crassa
          Length = 527

 Score =  101 bits (242), Expect = 1e-20
 Identities = 53/128 (41%), Positives = 79/128 (61%), Gaps = 1/128 (0%)
 Frame = +1

Query: 205 NVGSQLQHMCGLDIDSKSSY-IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGS 381
           ++G ++Q +  L+ + + +   R + IICTIGP + +V  + K+ + G+NV RMNFSHGS
Sbjct: 10  SLGGKIQWLAQLNTEFQPAREFRRTSIICTIGPKTNSVEAINKLRDAGLNVVRMNFSHGS 69

Query: 382 HEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 561
           +EYH   I N R+AEK +    G P  +AIALDTKGPEIRTG  +     ++ +  G  +
Sbjct: 70  YEYHQSVIDNARQAEKVHP---GRP--IAIALDTKGPEIRTGNTK--NDEDIPISAGTIL 122

Query: 562 KLTTSSDY 585
            +TT   Y
Sbjct: 123 NITTDEKY 130


>UniRef50_P80885 Cluster: Pyruvate kinase; n=161; Bacteria|Rep:
           Pyruvate kinase - Bacillus subtilis
          Length = 585

 Score = 99.5 bits (237), Expect = 5e-20
 Identities = 52/99 (52%), Positives = 69/99 (69%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+CTIGPAS ++ +L K+ME+GMNVAR+NFSHG  E H   I+N REA K    K
Sbjct: 1   MRKTKIVCTIGPASESIEMLTKLMESGMNVARLNFSHGDFEEHGARIKNIREASK----K 56

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 561
           LG   ++ I LDTKGPEIRT  +E GG   +EL+ G+ +
Sbjct: 57  LGK--NVGILLDTKGPEIRTHTMENGG---IELETGKEL 90


>UniRef50_Q9M057 Cluster: Pyruvate kinase; n=11; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 510

 Score = 98.3 bits (234), Expect = 1e-19
 Identities = 51/102 (50%), Positives = 69/102 (67%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           IICT+GP SR+V ++EK+++ GMNVAR NFSHGSH YH ET+ N R A  +      +  
Sbjct: 20  IICTLGPVSRSVEMIEKLLKAGMNVARFNFSHGSHSYHQETLDNLRTAMDN------TGI 73

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 585
             A+ LDTKGPEIRTG L+ G    ++L +G+  ++T S DY
Sbjct: 74  LSAVMLDTKGPEIRTGFLKEG--KPIQLNQGQ--EITISIDY 111


>UniRef50_Q2TSW8 Cluster: Pyruvate kinase; n=4; stramenopiles|Rep:
           Pyruvate kinase - Phaeodactylum tricornutum
          Length = 543

 Score = 98.3 bits (234), Expect = 1e-19
 Identities = 55/106 (51%), Positives = 68/106 (64%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+CTIGPA  NV  LE ++E+GMNVAR NFSHG H  H   +   R+A ++     
Sbjct: 31  RRTKIVCTIGPACWNVDQLEILIESGMNVARFNFSHGDHAGHGAVLERVRQAAQNKGR-- 88

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 585
               ++AI LDTKGPEIRTG    G S ++EL KGETI LT  SDY
Sbjct: 89  ----NIAILLDTKGPEIRTGFFANGAS-KIELVKGETIVLT--SDY 127


>UniRef50_Q04668 Cluster: Pyruvate kinase; n=2; Leishmania
           braziliensis|Rep: Pyruvate kinase - Leishmania
           braziliensis
          Length = 91

 Score = 97.5 bits (232), Expect = 2e-19
 Identities = 54/99 (54%), Positives = 72/99 (72%), Gaps = 1/99 (1%)
 Frame = +1

Query: 214 SQLQHMCGLDIDSKSSYIRLSG-IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEY 390
           SQL H   L I      +R +G I+CTIGP++++V  L+ ++++GM+VARMNFSHGSHEY
Sbjct: 2   SQLAHNLTLSIFEP---LRTTGTIVCTIGPSTQSVEALKGLIKSGMSVARMNFSHGSHEY 58

Query: 391 HAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG 507
           H  TI N R+A    +A+LG   ++AIALDTKGPEIRTG
Sbjct: 59  HQTTINNVRQA----AAELG--VNIAIALDTKGPEIRTG 91


>UniRef50_Q9VD23 Cluster: Pyruvate kinase; n=5; Coelomata|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 744

 Score = 97.1 bits (231), Expect = 3e-19
 Identities = 47/80 (58%), Positives = 57/80 (71%), Gaps = 1/80 (1%)
 Frame = +1

Query: 346 MNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGG 525
           M V RMNFSHGSHEYH +TI+  R+A   Y  + G P +LAIALDTKGPEIRTG L GG 
Sbjct: 1   MRVVRMNFSHGSHEYHCQTIQAARKAIAMYVEQTGLPRTLAIALDTKGPEIRTGKLAGGN 60

Query: 526 S-AEVELKKGETIKLTTSSD 582
             AE+ELK G+ + L+T  +
Sbjct: 61  DRAEIELKTGDKVTLSTKKE 80


>UniRef50_O44006 Cluster: Pyruvate kinase; n=10; cellular
           organisms|Rep: Pyruvate kinase - Eimeria tenella
          Length = 531

 Score = 91.9 bits (218), Expect = 1e-17
 Identities = 44/102 (43%), Positives = 65/102 (63%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CT+GP+  +V  + ++++ GMNV R+NFSHG HE H   ++N +EA K    K     
Sbjct: 60  IVCTMGPSCWDVDKMVQLIDAGMNVCRLNFSHGDHEAHGRVVKNLQEALKQRPGK----- 114

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 585
            +A+ LDTKGPEIRTG+LE  G   +EL  G+ +K+ T   +
Sbjct: 115 RVALLLDTKGPEIRTGMLE--GDKPIELHAGDMLKIVTDYSF 154


>UniRef50_Q4U977 Cluster: Pyruvate kinase, putative; n=3;
           Piroplasmida|Rep: Pyruvate kinase, putative - Theileria
           annulata
          Length = 513

 Score = 91.1 bits (216), Expect = 2e-17
 Identities = 44/98 (44%), Positives = 65/98 (66%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CT+GPA  NV  + +M+++GMN+ R NFSHG+HE H +T+   +EA KS         
Sbjct: 42  IVCTMGPACGNVETIIQMVKSGMNICRFNFSHGNHETHTKTLNLVKEALKSVPEA----- 96

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           ++ + LDTKGPEIRTG L+      + L++G T+K+TT
Sbjct: 97  NIGLMLDTKGPEIRTGFLK--NHTPITLEEGSTLKITT 132


>UniRef50_Q8EX62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Leptospira interrogans
          Length = 486

 Score = 90.2 bits (214), Expect = 3e-17
 Identities = 49/103 (47%), Positives = 68/103 (66%)
 Frame = +1

Query: 250 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 429
           S+SS  R + IICTIGPA+ +  +++ + E GMNVAR+N SHG+H++H   IRN +   K
Sbjct: 3   SESSVFRKTKIICTIGPATSDKKMIQALAEAGMNVARLNMSHGNHDFHRSIIRNIKSLNK 62

Query: 430 SYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGET 558
                L +P  +AI LDT+GPEIRTG L+      ++LK GET
Sbjct: 63  DV---LKNP--IAILLDTQGPEIRTGDLQ---VDHLDLKVGET 97


>UniRef50_P77983 Cluster: Pyruvate kinase I; n=29; Bacteria|Rep:
           Pyruvate kinase I - Salmonella typhimurium
          Length = 470

 Score = 89.0 bits (211), Expect = 7e-17
 Identities = 48/98 (48%), Positives = 62/98 (63%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CTIGP + +  +L KM++ GMNV R+NFSHG +  H + I+N R    +  +K G   
Sbjct: 6   IVCTIGPKTESEEMLSKMLDAGMNVMRLNFSHGDYAEHGQRIQNLR----NVMSKTGK-- 59

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
             AI LDTKGPEIRT  LEGG   +V LK G+T   TT
Sbjct: 60  KAAILLDTKGPEIRTIKLEGGN--DVSLKAGQTFTFTT 95


>UniRef50_UPI0000DA20CA Cluster: PREDICTED: similar to Pyruvate
           kinase isozyme M2; n=4; Rattus norvegicus|Rep:
           PREDICTED: similar to Pyruvate kinase isozyme M2 -
           Rattus norvegicus
          Length = 123

 Score = 88.6 bits (210), Expect = 9e-17
 Identities = 44/89 (49%), Positives = 62/89 (69%)
 Frame = +1

Query: 220 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 399
           L+HMC L+IDS       +GIICTIG   ++V +L+ M+ +GMNVA +NFSHG+HEYHAE
Sbjct: 27  LEHMCCLEIDSAPIMAHNTGIICTIG---QSVEMLKGMIMSGMNVAHLNFSHGTHEYHAE 83

Query: 400 TIRNCREAEKSYSAKLGSPFSLAIALDTK 486
           TI+N     +S+++      S+ +ALDTK
Sbjct: 84  TIKNVCATTESFASDPILYLSIVVALDTK 112


>UniRef50_Q1FK29 Cluster: Pyruvate kinase; n=4; Clostridiales|Rep:
           Pyruvate kinase - Clostridium phytofermentans ISDg
          Length = 580

 Score = 88.6 bits (210), Expect = 9e-17
 Identities = 49/104 (47%), Positives = 65/104 (62%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+CT+GPA+ + AVL ++M  GM+VAR NFSHG +E H       R      SA+
Sbjct: 1   MRKTKIVCTLGPATEDDAVLRQLMIEGMDVARFNFSHGDYEQHTRNYERIRR----LSAE 56

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTS 576
           L  P  +A  LDTKGPEIR G  E G   ++ELKKG+   LTT+
Sbjct: 57  LKLP--IATLLDTKGPEIRIGTFENG---KIELKKGQIFTLTTN 95


>UniRef50_Q22Z06 Cluster: Pyruvate kinase family protein; n=3;
           Oligohymenophorea|Rep: Pyruvate kinase family protein -
           Tetrahymena thermophila SB210
          Length = 505

 Score = 88.2 bits (209), Expect = 1e-16
 Identities = 45/102 (44%), Positives = 64/102 (62%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+CTIGP+  +   L +++E GMNVAR+NFSHG H  H ET+R  +EA K+     
Sbjct: 22  RKTKIVCTIGPSCWDHDNLVQLLENGMNVARLNFSHGDHAGHGETVRRLKEAFKA----- 76

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
                 A+ LDTKGPEIRTGL++      + L  G+ +++TT
Sbjct: 77  RKNIQCALMLDTKGPEIRTGLVKDQTKKLINLVAGQELEITT 118


>UniRef50_Q9VFG4 Cluster: Pyruvate kinase; n=3; Sophophora|Rep:
           Pyruvate kinase - Drosophila melanogaster (Fruit fly)
          Length = 1010

 Score = 85.0 bits (201), Expect = 1e-15
 Identities = 42/95 (44%), Positives = 59/95 (62%)
 Frame = +1

Query: 214 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 393
           SQL +   L   + +  + L+ IICTIGP+S    VL  ++  GM V R++FS G+H+ H
Sbjct: 165 SQLDYQSRLQFQAPALRLPLTSIICTIGPSSSQPEVLLNLIHAGMKVVRLDFSDGTHDCH 224

Query: 394 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEI 498
            + I+  R+A   Y+ + G P SLAIALDTKGP I
Sbjct: 225 CQAIQAARKAIAMYAEETGLPRSLAIALDTKGPVI 259


>UniRef50_Q6MLB5 Cluster: Pyruvate kinase; n=1; Bdellovibrio
           bacteriovorus|Rep: Pyruvate kinase - Bdellovibrio
           bacteriovorus
          Length = 495

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 45/103 (43%), Positives = 64/103 (62%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+ TIGPA+R+   LEK ++ GMNVAR+NFSHGSHE H + + + R+  K   A  
Sbjct: 5   RRAKIVATIGPATRDEKNLEKAIKAGMNVARLNFSHGSHEDHLKVVHSLRKLSKELQA-- 62

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTS 576
                +AI  D +GP+IR G  E G    +E+K GE + +TT+
Sbjct: 63  ----PVAILQDLQGPKIRVGKFENG---SIEIKPGEKLVVTTA 98


>UniRef50_Q5C2V0 Cluster: Pyruvate kinase; n=1; Schistosoma
           japonicum|Rep: Pyruvate kinase - Schistosoma japonicum
           (Blood fluke)
          Length = 168

 Score = 84.6 bits (200), Expect = 2e-15
 Identities = 43/124 (34%), Positives = 73/124 (58%)
 Frame = +1

Query: 214 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 393
           S +QH+    ID    ++R + ++CT+G    +   +++M+++GMN+ R+N S G+ E +
Sbjct: 25  SLMQHISNQSIDHAPFFVRHTNLVCTLGDHWDSDEKIDQMIKSGMNILRLNLSMGTKEKY 84

Query: 394 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           AE IR  R  E+SY     +P S+ IALD   P +RTGL+     A V ++ G+ + LT 
Sbjct: 85  AEVIRRVRRLEESYDY---NP-SVGIALDLSAPPVRTGLINESVDAVVVIQTGQMVTLTI 140

Query: 574 SSDY 585
           + +Y
Sbjct: 141 NDEY 144


>UniRef50_P94685 Cluster: Pyruvate kinase; n=8; Chlamydiaceae|Rep:
           Pyruvate kinase - Chlamydia trachomatis
          Length = 485

 Score = 84.2 bits (199), Expect = 2e-15
 Identities = 44/98 (44%), Positives = 62/98 (63%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           IICTIGPA+    +LEK+++ GMNVAR+NFSHG+HE H  TI   +E  +          
Sbjct: 7   IICTIGPATNTPEMLEKLLDAGMNVARLNFSHGTHESHGRTIAILKELREKRQV------ 60

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
            LAI LDTKGPEIR G +E    + ++++ G+ + L +
Sbjct: 61  PLAIMLDTKGPEIRLGQVE----SPIKVQPGDRLTLVS 94


>UniRef50_A4E9R2 Cluster: Pyruvate kinase; n=1; Collinsella
           aerofaciens ATCC 25986|Rep: Pyruvate kinase -
           Collinsella aerofaciens ATCC 25986
          Length = 486

 Score = 82.6 bits (195), Expect = 6e-15
 Identities = 48/105 (45%), Positives = 65/105 (61%), Gaps = 3/105 (2%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CT+GPA  +   + +M++ GMNVAR NFSHGS++ H   I   R   K    +LG P 
Sbjct: 7   IVCTMGPACDSDETIREMIKAGMNVARFNFSHGSYDEHHGRIERVRRISK----ELGLP- 61

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT---TSSDY 585
            + I LDTKGPE+RTGLL  G   +V +K G+ I +T   TS D+
Sbjct: 62  -VGILLDTKGPEVRTGLLVDG--KKVAVKTGDKIVVTAQPTSEDF 103


>UniRef50_Q090R5 Cluster: Pyruvate kinase; n=1; Stigmatella
           aurantiaca DW4/3-1|Rep: Pyruvate kinase - Stigmatella
           aurantiaca DW4/3-1
          Length = 515

 Score = 82.2 bits (194), Expect = 8e-15
 Identities = 47/103 (45%), Positives = 65/103 (63%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+CT+GPAS++  +LE ++E GM+VAR+NFSHGSHE HAE I   R A    S K
Sbjct: 10  MRRAKIVCTLGPASQSQDMLEALIEAGMDVARLNFSHGSHEQHAENIAKLRAA----SLK 65

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           L    ++ I  D +GP+IRTG    G +    LK+G    +TT
Sbjct: 66  LRK--AVGILGDLQGPKIRTGRFITGSTV---LKEGAIFSITT 103


>UniRef50_P52489 Cluster: Pyruvate kinase 2; n=33; Dikarya|Rep:
           Pyruvate kinase 2 - Saccharomyces cerevisiae (Baker's
           yeast)
          Length = 506

 Score = 82.2 bits (194), Expect = 8e-15
 Identities = 43/98 (43%), Positives = 62/98 (63%)
 Frame = +1

Query: 214 SQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYH 393
           S+LQ +  L I +    +R + II TIGP + +   +  + + G+N+ R+NFSHGS+E+H
Sbjct: 4   SRLQRLANLKIGTPQQ-LRRTSIIGTIGPKTNSCEAITALRKAGLNIIRLNFSHGSYEFH 62

Query: 394 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG 507
              I N  ++E+ +    G P  LAIALDTKGPEIRTG
Sbjct: 63  QSVIENAVKSEQQFP---GRP--LAIALDTKGPEIRTG 95


>UniRef50_Q55863 Cluster: Pyruvate kinase 1; n=5; Cyanobacteria|Rep:
           Pyruvate kinase 1 - Synechocystis sp. (strain PCC 6803)
          Length = 483

 Score = 81.8 bits (193), Expect = 1e-14
 Identities = 44/96 (45%), Positives = 64/96 (66%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+ TIGPAS +V V+ +M++ GMNVAR+NFSHGS+E HA  +R  R  E+    ++ +P 
Sbjct: 20  IVATIGPASSSVEVIRQMVDAGMNVARLNFSHGSYEDHATMVRLLRSVEQ----EMDTPI 75

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
           +L    D +GP+IR G L GG   E +L++GE + L
Sbjct: 76  TL--LQDLQGPKIRIGQLPGG---EKQLREGEKVSL 106


>UniRef50_Q1NTW3 Cluster: Pyruvate kinase; n=1; delta
           proteobacterium MLMS-1|Rep: Pyruvate kinase - delta
           proteobacterium MLMS-1
          Length = 493

 Score = 81.4 bits (192), Expect = 1e-14
 Identities = 44/102 (43%), Positives = 64/102 (62%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+CTIGPA+ +   + ++ E GMNVAR+N SHGS E+H   I N +   K Y+   
Sbjct: 16  RRTKIVCTIGPATASFEAICRLAEQGMNVARLNMSHGSREWHRGVIGNIKRYNKKYAG-- 73

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
               SLA+ LDT+G EIR+G L+     ++EL+ G+ + LTT
Sbjct: 74  ----SLAVLLDTRGAEIRSGDLK----QDLELRVGDGLTLTT 107


>UniRef50_Q08SK3 Cluster: Pyruvate kinase; n=2;
           Cystobacterineae|Rep: Pyruvate kinase - Stigmatella
           aurantiaca DW4/3-1
          Length = 481

 Score = 81.4 bits (192), Expect = 1e-14
 Identities = 45/103 (43%), Positives = 65/103 (63%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + IICT+GPAS    V+E ++  GMNVAR+NFSHG +E H   +   R+     S K
Sbjct: 16  MRKAKIICTLGPASDTPEVIEGLVRAGMNVARINFSHGVYEDHRRRVNTLRKV----SRK 71

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           LG P  +AI  D +GP+IR G  EGG   ++ ++ G+T+ +TT
Sbjct: 72  LGIP--VAILQDIQGPKIRLGRFEGG---QLLVQAGQTVTVTT 109


>UniRef50_A5C814 Cluster: Pyruvate kinase; n=1; Vitis vinifera|Rep:
           Pyruvate kinase - Vitis vinifera (Grape)
          Length = 621

 Score = 80.2 bits (189), Expect = 3e-14
 Identities = 44/112 (39%), Positives = 67/112 (59%), Gaps = 6/112 (5%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+CTIGP++ +  ++ K+ ETGMNVAR+N SHG H  H +TI   +E    +  K+
Sbjct: 166 RKTKIVCTIGPSTSSREMIWKLAETGMNVARLNMSHGDHASHKKTIDLVKEYNAQFEDKV 225

Query: 448 GSPFSLAIALDTKGPEIRTG------LLEGGGSAEVELKKGETIKLTTSSDY 585
                +AI LDTKGPE+R+G      +L+ G      +K+G + + T S +Y
Sbjct: 226 -----IAIMLDTKGPEVRSGDVPKPIMLKEGQEFNFTIKRGVSSENTVSVNY 272


>UniRef50_Q1Q4I4 Cluster: Strongly similar to pyruvate kinase; n=1;
           Candidatus Kuenenia stuttgartiensis|Rep: Strongly
           similar to pyruvate kinase - Candidatus Kuenenia
           stuttgartiensis
          Length = 472

 Score = 79.4 bits (187), Expect = 6e-14
 Identities = 46/102 (45%), Positives = 62/102 (60%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+CTIGPAS + A++E+++  GMNVAR+NFSHG    H E I + R    + S KL
Sbjct: 5   RKTKIVCTIGPASNSPAMIEQLICAGMNVARLNFSHGELSQHKECISHIR----AISEKL 60

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
             P  +A+  D  GP+IR G+L G     V LK  +T  LTT
Sbjct: 61  MQP--VAVLQDLSGPKIRIGMLSGDA---VTLKTNDTFTLTT 97


>UniRef50_Q1K4D5 Cluster: Pyruvate kinase; n=1; Desulfuromonas
           acetoxidans DSM 684|Rep: Pyruvate kinase -
           Desulfuromonas acetoxidans DSM 684
          Length = 474

 Score = 79.4 bits (187), Expect = 6e-14
 Identities = 44/104 (42%), Positives = 63/104 (60%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+CT+GPAS + A LE+M+ +GMNVAR+NFSHG H+ H + I   R   K    +
Sbjct: 1   MRRTKIVCTVGPASADEATLEQMISSGMNVARLNFSHGDHDSHQQLIERIRAVAK----R 56

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTS 576
           L  P  +AI  D  GP+IR G L   G   V L +G+ + L ++
Sbjct: 57  LNQP--VAILQDLCGPKIRLGQLPEQG---VRLHQGDAVSLCST 95


>UniRef50_Q2IHE2 Cluster: Pyruvate kinase; n=1; Anaeromyxobacter
           dehalogenans 2CP-C|Rep: Pyruvate kinase -
           Anaeromyxobacter dehalogenans (strain 2CP-C)
          Length = 489

 Score = 78.2 bits (184), Expect = 1e-13
 Identities = 43/106 (40%), Positives = 67/106 (63%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+ T+GPAS    VL +++E G++VAR+NFSHG HE HA  +   R A    S  
Sbjct: 1   MRRAKIVATLGPASGEPDVLARLLEQGVDVARLNFSHGRHEDHARMLDKIRAA----SRH 56

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
           LG   ++A+  D +GP+IRTG L+  G A V+++ G+ + +TT  +
Sbjct: 57  LGK--AVAVLQDLQGPKIRTGPLK-AGKAGVQVEAGQELVITTEGE 99


>UniRef50_Q4YDL9 Cluster: Putative uncharacterized protein; n=1;
           Plasmodium berghei|Rep: Putative uncharacterized protein
           - Plasmodium berghei
          Length = 158

 Score = 78.2 bits (184), Expect = 1e-13
 Identities = 41/102 (40%), Positives = 61/102 (59%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CT+GPA ++V  L ++++ GM++ R NFSHG+H+ H +   N  +A+           
Sbjct: 41  IVCTLGPACKSVETLVQLIDAGMDICRFNFSHGTHDDH-KMFENVLKAQAQ-----RPNC 94

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 585
           +L + LD KGPEIRTGLL   G+ E  LK+G  +KL     Y
Sbjct: 95  TLGMLLDNKGPEIRTGLL---GNKEAHLKEGSKLKLVADYSY 133


>UniRef50_Q40546 Cluster: Pyruvate kinase isozyme G, chloroplast
           precursor; n=58; Viridiplantae|Rep: Pyruvate kinase
           isozyme G, chloroplast precursor - Nicotiana tabacum
           (Common tobacco)
          Length = 562

 Score = 77.0 bits (181), Expect = 3e-13
 Identities = 46/126 (36%), Positives = 70/126 (55%), Gaps = 9/126 (7%)
 Frame = +1

Query: 235 GLDIDSKSSYI---RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETI 405
           G  +  +S Y+   R + I+CTIGP++ +  ++ K+ E GMNVAR+N SHG H  H  TI
Sbjct: 77  GYSLGQESVYLNSPRKTKIVCTIGPSTSSREMIWKLAEAGMNVARLNMSHGDHASHQRTI 136

Query: 406 RNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG------LLEGGGSAEVELKKGETIKL 567
              +E    +  K+     +AI LDTKGPE+ +G      LL+ G      +K+G + + 
Sbjct: 137 DLVKEYNAQFEDKV-----IAIMLDTKGPEVISGDVPKPILLKEGQEFNFSIKRGVSTED 191

Query: 568 TTSSDY 585
           T S +Y
Sbjct: 192 TVSVNY 197


>UniRef50_Q6MAN9 Cluster: Pyruvate kinase; n=1; Candidatus
           Protochlamydia amoebophila UWE25|Rep: Pyruvate kinase -
           Protochlamydia amoebophila (strain UWE25)
          Length = 598

 Score = 76.6 bits (180), Expect = 4e-13
 Identities = 40/81 (49%), Positives = 52/81 (64%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CTIGPA  ++  + +++  GMNVAR+NFSHG+ E H  TI   +EA      +L  P 
Sbjct: 8   IVCTIGPACNSLEKIIELINVGMNVARLNFSHGTQEEHLRTINLLKEAR----CQLNLP- 62

Query: 460 SLAIALDTKGPEIRTGLLEGG 522
            LAI LDTKGPEIR G +  G
Sbjct: 63  -LAIMLDTKGPEIRLGKIRDG 82


>UniRef50_A3I0G9 Cluster: Pyruvate kinase; n=3;
           Flexibacteraceae|Rep: Pyruvate kinase - Algoriphagus sp.
           PR1
          Length = 476

 Score = 76.6 bits (180), Expect = 4e-13
 Identities = 42/97 (43%), Positives = 54/97 (55%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+ TIGPAS N   +  +   G NV R+NFSHGSH+ H E I   R+  K  +  LG   
Sbjct: 11  ILATIGPASNNYETISSLAAAGANVFRLNFSHGSHDIHQEVIEIIRKINKEQNLNLG--- 67

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
              I  D +GP+IR G +E  G   VE+K GE I +T
Sbjct: 68  ---ILQDLQGPKIRVGEVENNG---VEIKPGEKITIT 98


>UniRef50_Q0W8N0 Cluster: Pyruvate kinase; n=7; cellular
           organisms|Rep: Pyruvate kinase - Uncultured methanogenic
           archaeon RC-I
          Length = 583

 Score = 76.6 bits (180), Expect = 4e-13
 Identities = 44/103 (42%), Positives = 59/103 (57%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+CTIGPA  +  +LEK+   GMNVAR+N SH  HE+  +TI N R      S  
Sbjct: 1   MRKTKIVCTIGPACDSQDMLEKLAVAGMNVARLNMSHADHEHTVQTINNIR----MVSEA 56

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           +G P  + I +D +GP+IR G L+        LK G T  LTT
Sbjct: 57  IGKP--IGILMDLQGPKIRVGTLQ----QPANLKPGGTFTLTT 93


>UniRef50_Q9KUN0 Cluster: Pyruvate kinase; n=24; cellular
           organisms|Rep: Pyruvate kinase - Vibrio cholerae
          Length = 470

 Score = 76.2 bits (179), Expect = 5e-13
 Identities = 44/100 (44%), Positives = 58/100 (58%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CTIGP + +V  L +++  GMNV R+NFSHG +  H   I N R+     + K     
Sbjct: 6   IVCTIGPKTESVEKLTELVNAGMNVMRLNFSHGDYVEHGTRITNFRKV-MEVTGK----- 59

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 579
            LAI LDTKGPEIRT  LE G   +V+L  G+    TT +
Sbjct: 60  QLAILLDTKGPEIRTIKLENGD--DVDLVAGQEFTFTTDT 97


>UniRef50_Q3JCE7 Cluster: Pyruvate kinase; n=1; Nitrosococcus oceani
           ATCC 19707|Rep: Pyruvate kinase - Nitrosococcus oceani
           (strain ATCC 19707 / NCIMB 11848)
          Length = 492

 Score = 76.2 bits (179), Expect = 5e-13
 Identities = 44/100 (44%), Positives = 63/100 (63%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R   I+CTIGPASR+ A+L KM+ +GMNVAR+NFSHG+HE H       REA    + +L
Sbjct: 24  RACRIVCTIGPASRSPAILRKMLLSGMNVARLNFSHGNHESHGRIACEIREA----AQRL 79

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
             P  +AI  D +G ++R G ++   S  + L++G+ I L
Sbjct: 80  MKP--VAILQDLQGHKVRVGKVQHPPS--LSLEEGQEILL 115


>UniRef50_Q8SQP0 Cluster: Pyruvate kinase; n=1; Encephalitozoon
           cuniculi|Rep: Pyruvate kinase - Encephalitozoon cuniculi
          Length = 519

 Score = 75.8 bits (178), Expect = 7e-13
 Identities = 38/103 (36%), Positives = 67/103 (65%)
 Frame = +1

Query: 271 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 450
           L+ I+CTIGP + +   ++++++ GM++AR+NFSHGS E H E IRN R+      ++ G
Sbjct: 96  LTKIVCTIGPRTSSREKIKELIDAGMSIARLNFSHGSREAHLEVIRNIRD------SRSG 149

Query: 451 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 579
           +   ++IALDT+GPE+R   L      +++++ GE ++ +  S
Sbjct: 150 AGRHVSIALDTRGPEVR---LRTPEMKDIKVEGGEVLRFSLLS 189


>UniRef50_Q1IHI1 Cluster: Pyruvate kinase; n=2; Bacteria|Rep:
           Pyruvate kinase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 509

 Score = 75.4 bits (177), Expect = 9e-13
 Identities = 40/101 (39%), Positives = 59/101 (58%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+CTIGPA    A ++++M  GM+VAR+NFSHG+H+ H   I+  R+         
Sbjct: 20  RRAKIVCTIGPACNTEAAMQELMRAGMDVARLNFSHGTHDEHLVVIQRLRKVAAEEQR-- 77

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
               S+ I  D +GP+IRTGLL+      V L+ G T+ +T
Sbjct: 78  ----SICILQDLQGPKIRTGLLK--DHKPVMLETGNTVTIT 112


>UniRef50_UPI00015BD1E0 Cluster: UPI00015BD1E0 related cluster; n=1;
           unknown|Rep: UPI00015BD1E0 UniRef100 entry - unknown
          Length = 477

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 41/97 (42%), Positives = 58/97 (59%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CTIGPAS+ V  L KM+E GMN+AR+NF+HGS E H   + N R+A K          
Sbjct: 11  IVCTIGPASQEVETLTKMIENGMNIARINFAHGSFEEHETVVENIRKASKIVGK------ 64

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
            + I  D  GP+IR G ++      +E+KKG+ + L+
Sbjct: 65  DVTIMGDLPGPKIRIGDIK-----PMEIKKGDILILS 96


>UniRef50_A7HIL5 Cluster: Pyruvate kinase; n=9; Bacteria|Rep:
           Pyruvate kinase - Anaeromyxobacter sp. Fw109-5
          Length = 491

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 42/106 (39%), Positives = 65/106 (61%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+ T+GPAS +  VL++M+  G++VAR+NFSHG HE HA+ +   R A    S  
Sbjct: 4   MRRAKIVATLGPASSDPDVLQRMLAAGVDVARLNFSHGRHEDHAQMLDRIRTA----SRH 59

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
           LG   ++A+  D +GP+IRTG L  G    V L+ G  + + T ++
Sbjct: 60  LGR--AVAVLQDLQGPKIRTGPLAAGREG-VRLEAGAELVIATDAE 102


>UniRef50_Q56XD5 Cluster: Pyruvate kinase; n=14; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 579

 Score = 74.9 bits (176), Expect = 1e-12
 Identities = 38/86 (44%), Positives = 55/86 (63%)
 Frame = +1

Query: 250 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 429
           SK +  R + I+CT+GP++    ++ K+ E GMNVARMN SHG H  H + I    +  K
Sbjct: 104 SKPTVRRKTKIVCTVGPSTNTREMIWKLAEAGMNVARMNMSHGDHASHKKVI----DLVK 159

Query: 430 SYSAKLGSPFSLAIALDTKGPEIRTG 507
            Y+A+     ++AI LDTKGPE+R+G
Sbjct: 160 EYNAQT-KDNTIAIMLDTKGPEVRSG 184


>UniRef50_Q8PYY4 Cluster: Pyruvate kinase; n=3;
           Methanosarcinaceae|Rep: Pyruvate kinase - Methanosarcina
           mazei (Methanosarcina frisia)
          Length = 477

 Score = 74.1 bits (174), Expect = 2e-12
 Identities = 44/97 (45%), Positives = 58/97 (59%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CTIGPAS +  ++ K+M  GMNVAR+NFSHG  E H+  +R  R+     + +LG   
Sbjct: 10  IVCTIGPASSSEEMIRKLMLAGMNVARINFSHGDFESHSRVVRIIRKV----ADELGR-- 63

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
           ++AI  D  GP+IR G LE      V L KG  I LT
Sbjct: 64  TIAILADLPGPKIRIGKLE---KEPVMLHKGNPITLT 97


>UniRef50_Q8TJ98 Cluster: Pyruvate kinase; n=2; Methanomicrobia|Rep:
           Pyruvate kinase - Methanosarcina acetivorans
          Length = 489

 Score = 73.7 bits (173), Expect = 3e-12
 Identities = 43/98 (43%), Positives = 56/98 (57%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CTIGPAS +  VL K++  GMNVAR+NFSHG  E H + IR  R+  +          
Sbjct: 22  IVCTIGPASFSEEVLRKLVLAGMNVARINFSHGDFESHGKVIRRVRKVAEELDR------ 75

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           ++AI  D  GP+IR G L+      + L KG  I LTT
Sbjct: 76  TVAILADLPGPKIRVGKLK---KEPLMLHKGNRITLTT 110


>UniRef50_UPI0000DB6F59 Cluster: PREDICTED: similar to Pyruvate
           kinase CG7070-PB, isoform B; n=1; Apis mellifera|Rep:
           PREDICTED: similar to Pyruvate kinase CG7070-PB, isoform
           B - Apis mellifera
          Length = 538

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 37/131 (28%), Positives = 72/131 (54%), Gaps = 2/131 (1%)
 Frame = +1

Query: 187 EKPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMN 366
           E+   A   ++L+H   L+I+S     RL+ I+ T+G  + +   +  +M  G N+ R+N
Sbjct: 12  EQIKAAYQNTRLEHNINLNINSSPKLARLTRIMVTLGRRNSHPEAVVSIMMAGANIVRLN 71

Query: 367 FSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSA--EVE 540
            +H + ++H  T+++ R+A  +        + L +A++ +GPEIR G   G  ++    +
Sbjct: 72  MAHETDKWHTATVQSVRKAGNTMYEFTSEIYPLGVAINLQGPEIRAGAFRGDKTSLGYAK 131

Query: 541 LKKGETIKLTT 573
           LK+G+ +KL T
Sbjct: 132 LKEGKMVKLVT 142


>UniRef50_A7CUA8 Cluster: Pyruvate kinase; n=1; Opitutaceae
           bacterium TAV2|Rep: Pyruvate kinase - Opitutaceae
           bacterium TAV2
          Length = 480

 Score = 73.3 bits (172), Expect = 4e-12
 Identities = 42/102 (41%), Positives = 62/102 (60%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           IR + I+ T+GPA+ +  +LEK++  G +VAR+N +H +HE+    IR  RE  K    +
Sbjct: 10  IRRTKIVFTLGPATESEEMLEKLIRAGADVARLNMAHANHEWTRMIIRRIREVSK----R 65

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
           +G    +AI +D KGPEIRTG +    S+ +ELK GE    T
Sbjct: 66  VGR--EIAIMMDIKGPEIRTGDV----SSPIELKAGEIFDFT 101


>UniRef50_Q8F253 Cluster: Pyruvate kinase; n=4; Leptospira|Rep:
           Pyruvate kinase - Leptospira interrogans
          Length = 478

 Score = 72.1 bits (169), Expect = 9e-12
 Identities = 38/101 (37%), Positives = 58/101 (57%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CTIGPAS +   +  +++ GM++ARMNFSHG+H+ H       R+ E+ +       F
Sbjct: 14  IVCTIGPASSSEETILSILKAGMDIARMNFSHGTHDSHKRVYDTLRKCEQIFG------F 67

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
            L I  D +GP+IRTG L+      + L K + I++   SD
Sbjct: 68  PLGIMADLQGPKIRTGKLK---LNSILLHKNQEIEIVPDSD 105


>UniRef50_Q2S3S2 Cluster: Pyruvate kinase; n=1; Salinibacter ruber
           DSM 13855|Rep: Pyruvate kinase - Salinibacter ruber
           (strain DSM 13855)
          Length = 476

 Score = 72.1 bits (169), Expect = 9e-12
 Identities = 35/104 (33%), Positives = 62/104 (59%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+CT+GPA+ +   L +++  GM+VARMNFSHG+HE H E +   RE  ++     
Sbjct: 3   RRTKIVCTLGPATTDPETLRRLVAAGMDVARMNFSHGTHEEHRERVETVREVAEAEGK-- 60

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 579
                + +  D +GP+IR G ++   +  V L +G+ ++++T +
Sbjct: 61  ----GITVLQDLQGPKIRVGAVQ---NDSVMLAEGDEVRVSTDT 97


>UniRef50_Q6A9P1 Cluster: Pyruvate kinase; n=4; Actinomycetales|Rep:
           Pyruvate kinase - Propionibacterium acnes
          Length = 477

 Score = 71.7 bits (168), Expect = 1e-11
 Identities = 39/106 (36%), Positives = 65/106 (61%), Gaps = 3/106 (2%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+ T+GPA  +   ++++ME GMN+AR+N SHG +  H E +    +  +S S +
Sbjct: 1   MRRAKIVNTLGPAVTSHDAMKELMEAGMNIARLNMSHGDYSEHQERL----DLVRSVSKE 56

Query: 445 LGSPFSLAIALDTKGPEIRTGLL---EGGGSAEVELKKGETIKLTT 573
           LG   ++A   D +GP+IRTGL    EG  + +++LK G+   +TT
Sbjct: 57  LG--LNVAALADLQGPKIRTGLFEKAEGESNGKIDLKIGDKFTITT 100


>UniRef50_A1BQT0 Cluster: Pyruvate kinase; n=2; Eukaryota|Rep:
           Pyruvate kinase - Monocercomonoides sp. PA203
          Length = 516

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 35/109 (32%), Positives = 64/109 (58%)
 Frame = +1

Query: 256 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 435
           +S+  L+ I+ T+GPA+     + +++  G+NV RMNFSHG+HE+H +  +  R+  +  
Sbjct: 32  ASFTPLTKIVATLGPATSTYETISQVVTAGVNVIRMNFSHGTHEFHEQLYKIVRKVAED- 90

Query: 436 SAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
              LG    +AI  D +GP++RT    GG   ++ +K+G+ + +  S +
Sbjct: 91  ---LGK--EVAIIADLQGPKVRTNTFPGG---KITIKRGDKVSIVGSPE 131


>UniRef50_Q40545 Cluster: Pyruvate kinase isozyme A, chloroplast
           precursor; n=15; Magnoliophyta|Rep: Pyruvate kinase
           isozyme A, chloroplast precursor - Nicotiana tabacum
           (Common tobacco)
          Length = 593

 Score = 71.3 bits (167), Expect = 2e-11
 Identities = 42/104 (40%), Positives = 56/104 (53%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + +ICTIGPA+     LE++ E GMNVAR+N  HG+ E+H   I   R   +      
Sbjct: 114 RRTKLICTIGPATCGFEQLERLAEGGMNVARINMCHGTREWHRMVIERLRRLNEE----- 168

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 579
              F++AI +DT+G EI  G L G  SA+ E   GE    T  S
Sbjct: 169 -KGFAVAIMMDTEGSEIHMGDLGGASSAKAE--DGEIWNFTVRS 209


>UniRef50_Q8YTZ8 Cluster: Pyruvate kinase; n=3; Nostocaceae|Rep:
           Pyruvate kinase - Anabaena sp. (strain PCC 7120)
          Length = 476

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 39/87 (44%), Positives = 55/87 (63%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + IICT+GPA+     LE ++E GMNVAR+NFSHG++++HA+T +  R+     SA 
Sbjct: 1   MRRTKIICTVGPATSAPERLEALVEAGMNVARLNFSHGAYDFHAQTAQYLRQ----ISAD 56

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGG 525
              P  +AI  D  GP+IR G L   G
Sbjct: 57  RQKP--VAIMQDLCGPKIRLGTLPPEG 81


>UniRef50_Q56301 Cluster: Pyruvate kinase; n=5; Thermococcaceae|Rep:
           Pyruvate kinase - Thermococcus litoralis
          Length = 220

 Score = 70.5 bits (165), Expect = 3e-11
 Identities = 40/98 (40%), Positives = 60/98 (61%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           II TIGPAS+    ++KM++ GM+VAR+NFSHG+ E HA+TI   R+  +    +     
Sbjct: 14  IIATIGPASKQKESIKKMIKAGMSVARINFSHGTLEEHAKTIETVRDVAEKLERR----- 68

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
            +AI  D  G ++R G ++G     V L+KG+ + LTT
Sbjct: 69  -VAILGDLPGLKMRVGKIKGD---SVTLRKGDKVVLTT 102


>UniRef50_Q5IX04 Cluster: Pyruvate kinase; n=1; Prototheca
           wickerhamii|Rep: Pyruvate kinase - Prototheca
           wickerhamii
          Length = 259

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 43/101 (42%), Positives = 60/101 (59%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R +  +CTIGP S +     ++ + GMNV R+N SHG H  H + I   RE    Y+A L
Sbjct: 100 RKTKTVCTIGPTSCDREAFFRLADAGMNVVRLNMSHGDHASHQQVIDLVRE----YNA-L 154

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
           G   +LAI LDTKGPE+R+G L    +  ++L+KG+ I  T
Sbjct: 155 GRR-NLAIMLDTKGPEVRSGDL----TQPLDLEKGDLITFT 190


>UniRef50_A7D456 Cluster: Pyruvate kinase; n=2;
           Halobacteriaceae|Rep: Pyruvate kinase - Halorubrum
           lacusprofundi ATCC 49239
          Length = 613

 Score = 70.1 bits (164), Expect = 4e-11
 Identities = 40/108 (37%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
 Frame = +1

Query: 196 TVANVGSQLQHMCGLDID-SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFS 372
           TV NV S     CG  +  +KS  +R + I+CTIGPAS +   +  + + GM+V R+N S
Sbjct: 5   TVTNVHSVATQPCGFFLSCAKSGDMRNAKIVCTIGPASDSRDAIRDLADAGMSVVRLNAS 64

Query: 373 HGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLE 516
           HG+  +  E I   R  +     ++  P  LA+ +D KGPE+RT  L+
Sbjct: 65  HGTTAHREEVIERARAVDN----EIDDP--LAVMVDLKGPEVRTAELD 106


>UniRef50_Q1IJ65 Cluster: Pyruvate kinase; n=6; Bacteria|Rep:
           Pyruvate kinase - Acidobacteria bacterium (strain
           Ellin345)
          Length = 485

 Score = 69.3 bits (162), Expect = 6e-11
 Identities = 39/100 (39%), Positives = 60/100 (60%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+ TIGPAS +  +LE+++ TG++VAR+NFSHG    H E I N R A    S + G   
Sbjct: 10  IVGTIGPASESPEMLERLIRTGLDVARLNFSHGDFSGHRERIANLRAA----SDRAGR-- 63

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 579
           ++A+  D  GP++R G ++   +  + L+ G+   LTT S
Sbjct: 64  AVAVLADLPGPKMRLGTIQ---NEPIHLRAGDPFTLTTDS 100


>UniRef50_Q6KHW9 Cluster: Pyruvate kinase; n=3; Mycoplasma|Rep:
           Pyruvate kinase - Mycoplasma mobile
          Length = 483

 Score = 68.9 bits (161), Expect = 8e-11
 Identities = 46/104 (44%), Positives = 61/104 (58%)
 Frame = +1

Query: 274 SGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGS 453
           S +I TIGP+S+N  +L++MM  GM   R NFSHG    HAE + N     K  + +L  
Sbjct: 17  SKMIATIGPSSQNKEILKQMMLKGMTTVRANFSHGD---HAEQL-NKFVLAKEVAKELNL 72

Query: 454 PFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 585
           P SL   LDTKGPEIR G ++  GS ++E+ K  T+ LT    Y
Sbjct: 73  PMSL--MLDTKGPEIRVGKMK-DGSQKIEVGKIITV-LTDEVSY 112


>UniRef50_P73534 Cluster: Pyruvate kinase 2; n=37; Bacteria|Rep:
           Pyruvate kinase 2 - Synechocystis sp. (strain PCC 6803)
          Length = 591

 Score = 68.9 bits (161), Expect = 8e-11
 Identities = 40/103 (38%), Positives = 61/103 (59%), Gaps = 1/103 (0%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+ TIGPA+++  VL ++++ G    R+NFSHG H YH ++IR  R+     + +L
Sbjct: 8   RRTKIVATIGPATQSKEVLRQLIQAGATTFRLNFSHGDHAYHQQSIRLIRQ----IAFEL 63

Query: 448 GSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTT 573
             P  + I  D +GP+IR G  L   GS  V+LK G+   LT+
Sbjct: 64  NQP--VGILQDLQGPKIRVGKFLNDAGS--VQLKNGDPYTLTS 102


>UniRef50_Q9RR62 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Deinococcus radiodurans
          Length = 482

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 38/101 (37%), Positives = 56/101 (55%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+ T+GPASR+  VL +M++ G+NV R+NFSHG  E H +T++  R+   S    +
Sbjct: 6   RATKIVATVGPASRSTEVLGRMIDVGLNVVRLNFSHGDLEDHRQTVQMVRDLAVSKGVTI 65

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
           G      I  D +GP+IR G    G    V L  G+   +T
Sbjct: 66  G------ILQDLQGPKIRVGRFAEG---SVTLNPGQKFVIT 97


>UniRef50_Q1AXJ8 Cluster: Pyruvate kinase; n=1; Rubrobacter
           xylanophilus DSM 9941|Rep: Pyruvate kinase - Rubrobacter
           xylanophilus (strain DSM 9941 / NBRC 16129)
          Length = 477

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 34/86 (39%), Positives = 56/86 (65%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+ T+GPA+ +   +  ++  G++V R+NFSHG+H+ H +  R  REA    +A+
Sbjct: 3   VRRTKIVATLGPATSSEESIGALVRAGVDVMRLNFSHGTHDMHLDNARTVREA----AAE 58

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGG 522
            G   ++AI  D +GP+IRTG +EGG
Sbjct: 59  AGR--NVAIMQDLQGPKIRTGEVEGG 82


>UniRef50_Q2TSW6 Cluster: Pyruvate kinase; n=1; Achlya
           bisexualis|Rep: Pyruvate kinase - Achlya bisexualis
           (Water mold)
          Length = 517

 Score = 68.5 bits (160), Expect = 1e-10
 Identities = 35/113 (30%), Positives = 62/113 (54%), Gaps = 1/113 (0%)
 Frame = +1

Query: 250 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 429
           SK+    ++ I+ T+GP S N    +++   G+ + R+NFSH +++     + + R ++ 
Sbjct: 23  SKNDAFSMTKIVGTVGPVSENAKTTQELTNAGLKIMRINFSHATYDEAHLRMSHLRASKG 82

Query: 430 SYSAKLGSPFSL-AIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 585
            ++   G  F++ A+ LDT+GPEIR G        ++ L KG+ I LTT   Y
Sbjct: 83  VHAKHTGKEFNVRAVLLDTQGPEIRGGAFP---EKKINLTKGDMITLTTDVQY 132


>UniRef50_Q2JLA2 Cluster: Pyruvate kinase; n=2; Synechococcus|Rep:
           Pyruvate kinase - Synechococcus sp. (strain
           JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
           B-Prime)
          Length = 619

 Score = 68.1 bits (159), Expect = 1e-10
 Identities = 41/102 (40%), Positives = 56/102 (54%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+ TIGPAS N A+L +M+  G    R+NFSHG HE H  +IR  R+     +  L
Sbjct: 8   RRTKIVATIGPASSNPAILREMILQGATTLRLNFSHGDHELHRRSIRLIRQT----AMDL 63

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           G    +AI  D +GP+IR G    G    + LK G+   LT+
Sbjct: 64  G--IQVAILQDLQGPKIRLGKFAEG---SITLKAGDPFVLTS 100


>UniRef50_Q44473 Cluster: Pyruvate kinase; n=4; Proteobacteria|Rep:
           Pyruvate kinase - Agrobacterium vitis (Rhizobium vitis)
          Length = 482

 Score = 67.7 bits (158), Expect = 2e-10
 Identities = 37/98 (37%), Positives = 57/98 (58%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R S I+ T+GPAS +  +L  +   G++  R+NFSHG+   HAE  RN R  E+ + A  
Sbjct: 7   RRSKIVATVGPASSSPDMLRSLFLAGVDTFRLNFSHGARADHAEVYRNIRALEQEHDA-- 64

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 561
               ++A+  D +GP+IR G+L  G    ++L +G TI
Sbjct: 65  ----AIAVLQDLQGPKIRIGVLAHG---RLDLARGSTI 95


>UniRef50_Q46078 Cluster: Pyruvate kinase; n=19; Actinobacteria
           (class)|Rep: Pyruvate kinase - Corynebacterium
           glutamicum (Brevibacterium flavum)
          Length = 475

 Score = 67.3 bits (157), Expect = 2e-10
 Identities = 37/101 (36%), Positives = 57/101 (56%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+CT+GPA  +   + +++E GM+VAR+NFSHG H  H +  +  REA +     +
Sbjct: 3   RRTKIVCTLGPAVASADGILRLVEDGMDVARLNFSHGDHPDHEQNYKWVREAAEKTGRAV 62

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
           G      I  D +GP+IR G    G +     + GETI++T
Sbjct: 63  G------ILADLQGPKIRLGRFTDGATV---WENGETIRIT 94


>UniRef50_Q7UF82 Cluster: Pyruvate kinase; n=1; Pirellula sp.|Rep:
           Pyruvate kinase - Rhodopirellula baltica
          Length = 476

 Score = 66.5 bits (155), Expect = 4e-10
 Identities = 38/102 (37%), Positives = 58/102 (56%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + II TIGPA+ +   L  ++E G++V R+N +HG+ E+  E +   R+  K  S   
Sbjct: 5   RHTKIIATIGPATESPEKLAALIEAGVDVMRLNMAHGTPEWVGEIVARIRKVSKDISR-- 62

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
                +A+ +D KGPEIRTG +E      +ELK G+ + L T
Sbjct: 63  ----HVAVMMDVKGPEIRTGAVEDA----IELKAGDELVLFT 96


>UniRef50_Q747D6 Cluster: Pyruvate kinase; n=6;
           Desulfuromonadales|Rep: Pyruvate kinase - Geobacter
           sulfurreducens
          Length = 480

 Score = 66.5 bits (155), Expect = 4e-10
 Identities = 37/102 (36%), Positives = 62/102 (60%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + II T+GP S +  ++ ++M+ G++V R+NFSHGS++   E I     A +  SA+ 
Sbjct: 6   RKTKIIATLGPVSSSPDMIRQLMDAGVDVFRLNFSHGSNDQRREVI----AAIRRLSAER 61

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           G    + I  D +GP+IRTG +E G    + L +G+++ +TT
Sbjct: 62  GK--EIGILADLQGPKIRTGRMENGA---IPLVRGDSLDITT 98


>UniRef50_A4MK73 Cluster: Pyruvate kinase; n=1; Petrotoga mobilis
           SJ95|Rep: Pyruvate kinase - Petrotoga mobilis SJ95
          Length = 478

 Score = 66.5 bits (155), Expect = 4e-10
 Identities = 38/97 (39%), Positives = 60/97 (61%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+CTIGPA+++  +++K++  GMNVAR+N SH +   H + +   ++  K     L  PF
Sbjct: 12  IVCTIGPATQDETMIKKLINAGMNVARLNTSHDTIADHEKRVNLIKKIRKD----LNIPF 67

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
             AI LD +GP+IRTG  E   + +V L++G+   LT
Sbjct: 68  --AILLDLEGPKIRTGKFE---TDQVMLEEGQKFILT 99


>UniRef50_Q9WY51 Cluster: Pyruvate kinase; n=3; Thermotogaceae|Rep:
           Pyruvate kinase - Thermotoga maritima
          Length = 466

 Score = 66.5 bits (155), Expect = 4e-10
 Identities = 39/103 (37%), Positives = 60/103 (58%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+CT+GP + +  ++EKM++ G+NV R+N SHG      + I   ++  +    K
Sbjct: 1   MRSTKIVCTVGPRTDSYEMIEKMIDLGVNVFRINTSHGDWNEQEQKILKIKDLRE----K 56

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
              P  +AI +D  GP+IRTG LE      VELK+G+   LTT
Sbjct: 57  KKKP--VAILIDLAGPKIRTGYLE---KEFVELKEGQIFTLTT 94


>UniRef50_Q82XE9 Cluster: Pyruvate kinase family; n=130;
           Proteobacteria|Rep: Pyruvate kinase family -
           Nitrosomonas europaea
          Length = 496

 Score = 66.1 bits (154), Expect = 6e-10
 Identities = 36/97 (37%), Positives = 59/97 (60%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+ T+GPAS N  VL +M+E G++V R+NFSHG+ + H  ++    E  +S +  
Sbjct: 2   MRRTKIVATLGPASSNAEVLGRMLEAGVDVIRINFSHGTKDEHIASV----ELVRSLARS 57

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGE 555
           LG   ++ +  D +GP+IR G  E G   ++ LK G+
Sbjct: 58  LGR--TVGVLADLQGPKIRIGKFEQG---KIRLKTGD 89


>UniRef50_A0L7K0 Cluster: Pyruvate kinase; n=1; Magnetococcus sp.
           MC-1|Rep: Pyruvate kinase - Magnetococcus sp. (strain
           MC-1)
          Length = 569

 Score = 65.7 bits (153), Expect = 8e-10
 Identities = 35/83 (42%), Positives = 52/83 (62%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+ T+GPA  +V  + +++E G++VAR+N SHG H+ H E I N REA  S  AK 
Sbjct: 3   RRAKIVATLGPACSSVEQITRLIEAGLDVARLNMSHGDHKAHLELIHNVREA--SRIAKR 60

Query: 448 GSPFSLAIALDTKGPEIRTGLLE 516
                +A+  D +GP+IR G L+
Sbjct: 61  ----EVALLCDLQGPKIRVGHLD 79


>UniRef50_O06134 Cluster: Pyruvate kinase; n=29; Bacteria|Rep:
           Pyruvate kinase - Mycobacterium tuberculosis
          Length = 472

 Score = 65.7 bits (153), Expect = 8e-10
 Identities = 35/104 (33%), Positives = 56/104 (53%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R   I+CT+GPA++   ++  ++E GM+VARMNFSHG ++ H       R A  +    +
Sbjct: 3   RRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVASDATGRAV 62

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 579
           G      +  D +GP+IR G    G +   E   GET+++T  +
Sbjct: 63  G------VLADLQGPKIRLGRFASGATHWAE---GETVRITVGA 97


>UniRef50_Q81N35 Cluster: Pyruvate kinase; n=11; Bacillus cereus
           group|Rep: Pyruvate kinase - Bacillus anthracis
          Length = 352

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 35/97 (36%), Positives = 54/97 (55%)
 Frame = +1

Query: 283 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 462
           +CTIGPAS N   L K++  GM + R+N SHG+HE H + IR  +  +           S
Sbjct: 6   VCTIGPASNNKETLAKLINNGMKIVRLNLSHGTHESHKDIIRLVKSLDD----------S 55

Query: 463 LAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           + I  D +GP+IR G ++G    ++ L+ G++  L T
Sbjct: 56  IKILGDVQGPKIRLGEIKG---EQITLQAGDSFMLRT 89


>UniRef50_Q6YQT6 Cluster: Pyruvate kinase; n=6; Candidatus
           Phytoplasma|Rep: Pyruvate kinase - Onion yellows
           phytoplasma
          Length = 446

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 38/97 (39%), Positives = 58/97 (59%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           IICT+GPAS +  +L+ +++TG+NVAR NFSH  +E     ++      K+ S KL    
Sbjct: 6   IICTLGPASYDKNILQALIQTGLNVARFNFSHAQYEQTKLLMKTI----KTISDKLDK-- 59

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
           +  + LDTKGPEIRT   +G     V ++K   +K++
Sbjct: 60  NTGLMLDTKGPEIRTHEFDG----VVTIQKDSEVKIS 92


>UniRef50_Q5V4I8 Cluster: Pyruvate kinase; n=4;
           Halobacteriaceae|Rep: Pyruvate kinase - Haloarcula
           marismortui (Halobacterium marismortui)
          Length = 610

 Score = 65.3 bits (152), Expect = 1e-09
 Identities = 36/106 (33%), Positives = 59/106 (55%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+CT+GPAS +V  +  + + GM+VAR+N SHGS E+  E I   R+ +++    
Sbjct: 15  MRSAKIVCTLGPASDSVDDIASLAKAGMSVARLNASHGSPEHRREMIDRIRQVDEAVEE- 73

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
                 +A  LD  GPE+RT  ++      ++L +G TI+     D
Sbjct: 74  -----PVAAMLDMPGPEVRTAEID----EPIQLTEGSTIRYVVGDD 110


>UniRef50_Q8G5M1 Cluster: Pyruvate kinase; n=23;
           Actinobacteridae|Rep: Pyruvate kinase - Bifidobacterium
           longum
          Length = 509

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 36/110 (32%), Positives = 66/110 (60%), Gaps = 2/110 (1%)
 Frame = +1

Query: 250 SKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEK 429
           ++ +++R + I+ TIGP++ +   L K++E GM+VAR+N SHG+ E H +   N R+A +
Sbjct: 25  NRQAFMRKAKIVDTIGPSTEDYDNLLKLVEAGMDVARLNRSHGTPEDHLKVYNNVRKASE 84

Query: 430 SYSAKLGSPFSLAIALDTKGPEIRTGLLE--GGGSAEVELKKGETIKLTT 573
           +         ++A  +D +GP+IR G  +    G  +V+L+ G+   +TT
Sbjct: 85  ATGR------NVAALVDLQGPKIRCGWFKKNADGEDKVQLQLGQEFVITT 128


>UniRef50_Q0C0E8 Cluster: Pyruvate kinase; n=1; Hyphomonas neptunium
           ATCC 15444|Rep: Pyruvate kinase - Hyphomonas neptunium
           (strain ATCC 15444)
          Length = 474

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 33/81 (40%), Positives = 48/81 (59%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+ T+GP SR+   +  + E G++V R+NFSHG H  H E ++  R AE    A +G P 
Sbjct: 13  IVATLGPGSRSPREVRALAEAGVDVFRLNFSHGEHAAHLEALKAVRAAE----AAVGWP- 67

Query: 460 SLAIALDTKGPEIRTGLLEGG 522
            LA   D +GP++R G  +GG
Sbjct: 68  -LATLADLQGPKVRVGKFDGG 87


>UniRef50_A6Q5W9 Cluster: Pyruvate kinase; n=2;
           Epsilonproteobacteria|Rep: Pyruvate kinase -
           Nitratiruptor sp. (strain SB155-2)
          Length = 458

 Score = 64.9 bits (151), Expect = 1e-09
 Identities = 39/99 (39%), Positives = 60/99 (60%)
 Frame = +1

Query: 271 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 450
           ++ I+ TIGP+S  +  ++K++  G+NV R+NFSH  H+ H  +I+  RE  K    KLG
Sbjct: 1   MTKIVATIGPSS--IEKIDKLILAGVNVFRLNFSHADHKTHKASIKKIRETAK----KLG 54

Query: 451 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
           +    AI  D  GP+IR G ++G     +EL KG+ I+L
Sbjct: 55  T--KTAILQDISGPKIRIGEVDG----ILELSKGDKIRL 87


>UniRef50_A6Q7D7 Cluster: Pyruvate kinase; n=19; cellular
           organisms|Rep: Pyruvate kinase - Sulfurovum sp. (strain
           NBC37-1)
          Length = 488

 Score = 64.5 bits (150), Expect = 2e-09
 Identities = 33/79 (41%), Positives = 48/79 (60%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           II TIGPA+ +   ++ +M  G+N+ R+NFSHG+HEYH+E +   R+A +      G   
Sbjct: 7   IIATIGPATDSYEKIKALMCAGVNLFRLNFSHGTHEYHSEVLGRIRKAIEETGLITG--- 63

Query: 460 SLAIALDTKGPEIRTGLLE 516
              I  D  GP+IR G+LE
Sbjct: 64  ---ILQDISGPKIRVGMLE 79


>UniRef50_Q6AII5 Cluster: Pyruvate kinase; n=1; Desulfotalea
           psychrophila|Rep: Pyruvate kinase - Desulfotalea
           psychrophila
          Length = 581

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 37/101 (36%), Positives = 56/101 (55%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           II T+GP S++V  +  +++ GMNVAR+N SHG  E +   I N +EA K       +  
Sbjct: 6   IIATLGPQSQSVEEIYSLIQAGMNVARINLSHGDAESYKHLISNVKEARKL------AEK 59

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
             AI LD +GPEIR   +E     ++ L  GE + +T  ++
Sbjct: 60  DTAILLDNRGPEIRVSEME----EDIHLVDGEELVITNRAE 96


>UniRef50_P19680 Cluster: Pyruvate kinase; n=1; Spiroplasma
           citri|Rep: Pyruvate kinase - Spiroplasma citri
          Length = 192

 Score = 64.1 bits (149), Expect = 2e-09
 Identities = 34/73 (46%), Positives = 44/73 (60%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           II TIGP++ +   +E++ +TGM   R+NFSHG H      I   RE     SAK+G P 
Sbjct: 15  IITTIGPSTHSPGAIEELFKTGMTTIRLNFSHGDHAEQGARIVWAREV----SAKIGKPI 70

Query: 460 SLAIALDTKGPEI 498
           S  + LDTKGPEI
Sbjct: 71  S--VLLDTKGPEI 81


>UniRef50_Q2I6K6 Cluster: Pyruvate kinase; n=1; uncultured delta
           proteobacterium DeepAnt-32C6|Rep: Pyruvate kinase -
           uncultured delta proteobacterium DeepAnt-32C6
          Length = 466

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 38/103 (36%), Positives = 56/103 (54%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+CTIGPA+     +  +++ GM+ AR+NFSHG+ + HA      RE     + +
Sbjct: 1   MRRAKIVCTIGPATHTREGIRALIDAGMDCARLNFSHGTQQGHARVAALVRE----LATE 56

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
            G P  +A+  D  GP+IR G    G    VEL +G    LTT
Sbjct: 57  AGRP--IALLADLCGPKIRVGRFPEGA---VELVEGTAFTLTT 94


>UniRef50_Q94KE3 Cluster: Pyruvate kinase; n=25; Magnoliophyta|Rep:
           Pyruvate kinase - Arabidopsis thaliana (Mouse-ear cress)
          Length = 527

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 42/112 (37%), Positives = 63/112 (56%), Gaps = 1/112 (0%)
 Frame = +1

Query: 250 SKSSYI-RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 426
           SKSS+   L+ I+ T+GP SR+V  L   ++ GM+VAR +FS G  +YH ET+ N + A 
Sbjct: 21  SKSSFFPALTKIVGTLGPKSRSVEALSGCLKAGMSVARFDFSWGDADYHQETLDNLKVAV 80

Query: 427 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
           +S + KL      A+ LDT GPE++   +       + LK    + LT + D
Sbjct: 81  RS-TKKL-----CAVMLDTVGPELQ---VINKSEKAITLKADGLVTLTPNQD 123


>UniRef50_Q9YEU2 Cluster: Pyruvate kinase; n=1; Aeropyrum
           pernix|Rep: Pyruvate kinase - Aeropyrum pernix
          Length = 458

 Score = 63.7 bits (148), Expect = 3e-09
 Identities = 33/96 (34%), Positives = 58/96 (60%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+ T+GP+S + ++L +M+  G++VAR+N SHG  E     + + R AE++   ++G   
Sbjct: 7   IVATVGPSSSSASILAQMLSLGVDVARINASHGGVEQWNSMLESLRRAEEAVGKRVG--- 63

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
              +A+D +GP +RT     G S  V+L+KG+ + L
Sbjct: 64  ---VAVDLEGPRVRT-----GNSEPVKLEKGDLVTL 91


>UniRef50_A6C474 Cluster: Pyruvate kinase; n=1; Planctomyces maris
           DSM 8797|Rep: Pyruvate kinase - Planctomyces maris DSM
           8797
          Length = 489

 Score = 62.9 bits (146), Expect = 5e-09
 Identities = 32/80 (40%), Positives = 52/80 (65%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           II T+GPAS +  +L+K++  G+++ R+NF+HG HE+ +E ++N  E     SA++  P 
Sbjct: 17  IIATVGPASDSREMLQKLIIAGVDLFRLNFAHGKHEWLSEIVKNIHE----ISAEMEKP- 71

Query: 460 SLAIALDTKGPEIRTGLLEG 519
            + I  D  GP+IR G+L G
Sbjct: 72  -IGILGDLSGPKIRLGVLPG 90


>UniRef50_A6FYT4 Cluster: Pyruvate kinase; n=1; Plesiocystis
           pacifica SIR-1|Rep: Pyruvate kinase - Plesiocystis
           pacifica SIR-1
          Length = 485

 Score = 62.1 bits (144), Expect = 9e-09
 Identities = 36/103 (34%), Positives = 59/103 (57%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+ T+GPAS +  ++  +M+ G++  R+NFSHGSHE HA+     RE + S   +
Sbjct: 6   LRRAKILGTLGPASNSDEMIGALMDAGLDAVRLNFSHGSHEDHAQVYGKVRE-QSSIRRR 64

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
                 +A+  D +GP+IR G +   G   + L+ GET+   T
Sbjct: 65  -----PVAVLGDLQGPKIRVGKIPDPG---MTLETGETLVFLT 99


>UniRef50_A6DH47 Cluster: Pyruvate kinase; n=1; Lentisphaera
           araneosa HTCC2155|Rep: Pyruvate kinase - Lentisphaera
           araneosa HTCC2155
          Length = 485

 Score = 62.1 bits (144), Expect = 9e-09
 Identities = 37/99 (37%), Positives = 60/99 (60%), Gaps = 1/99 (1%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+ T+GP ++    L++++E G++V R+NFSHGSHE HAE I+    A       +G   
Sbjct: 9   IVSTLGPTTKGR--LKELIEEGVDVFRLNFSHGSHEEHAERIQEVISAATELKRTVG--- 63

Query: 460 SLAIALDTKGPEIRTG-LLEGGGSAEVELKKGETIKLTT 573
              I  D +GP+IR G ++EGG    ++L+ G+ + +TT
Sbjct: 64  ---ILGDLQGPKIRCGKIIEGG----IQLEAGQELVITT 95


>UniRef50_Q2FMN4 Cluster: Pyruvate kinase; n=1; Methanospirillum
           hungatei JF-1|Rep: Pyruvate kinase - Methanospirillum
           hungatei (strain JF-1 / DSM 864)
          Length = 500

 Score = 62.1 bits (144), Expect = 9e-09
 Identities = 31/82 (37%), Positives = 50/82 (60%)
 Frame = +1

Query: 256 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 435
           S  +R + II TIGPAS N  ++ +M+ +GM++AR+N SHGS  +H ET++  R      
Sbjct: 29  SCTMRRTKIIATIGPASSNPRIIREMILSGMDIARLNLSHGSPPWHEETVQQIRALADEL 88

Query: 436 SAKLGSPFSLAIALDTKGPEIR 501
           + ++G      I +D  GP++R
Sbjct: 89  NREIG------ILVDIPGPKLR 104


>UniRef50_A0QNT2 Cluster: Pyruvate kinase; n=1; Mycobacterium
           smegmatis str. MC2 155|Rep: Pyruvate kinase -
           Mycobacterium smegmatis (strain ATCC 700084 / mc(2)155)
          Length = 477

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 35/102 (34%), Positives = 54/102 (52%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+CT+GPA+   +VL ++++ GM+VAR+NFSH +H  H+      RE        +
Sbjct: 4   RRAKIVCTLGPATATSSVLTELVDAGMDVARLNFSHSTHAEHSALYGMVREIAAQRGRVV 63

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           G      +  D +GP+IR G    G    V    GE + +TT
Sbjct: 64  G------VLADLQGPKIRLGCFADG---PVVWATGEHVTITT 96


>UniRef50_A0L5K6 Cluster: Pyruvate kinase; n=5; Proteobacteria|Rep:
           Pyruvate kinase - Magnetococcus sp. (strain MC-1)
          Length = 483

 Score = 61.7 bits (143), Expect = 1e-08
 Identities = 38/101 (37%), Positives = 58/101 (57%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           IR + II T+GP + +   ++ +  TG++  R+NFSHGSHE H       R  E+    +
Sbjct: 4   IRRTKIIATLGPNASSRDFIKHLALTGVDTFRLNFSHGSHEDHRRRHGWIRSVEE----E 59

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
           LG P  L I +D +GP++R G  E   ++EVEL +G+   L
Sbjct: 60  LGRP--LGIMMDLQGPKLRIGTFE---NSEVELVRGQKFAL 95


>UniRef50_A7CAK5 Cluster: Pyruvate kinase; n=3; Ralstonia
           pickettii|Rep: Pyruvate kinase - Ralstonia pickettii 12D
          Length = 507

 Score = 60.5 bits (140), Expect = 3e-08
 Identities = 37/107 (34%), Positives = 55/107 (51%)
 Frame = +1

Query: 247 DSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAE 426
           ++K    R + I+ T+GPAS +   +  + + G +V R+NFSHGSHE H +     R  E
Sbjct: 13  NTKMRRFRNTKILATLGPASSDKDTIRALFDAGADVFRLNFSHGSHEDHRKRYDTVRAVE 72

Query: 427 KSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
               A+ G P  + I  D +GP++R G    G    V LK G+   L
Sbjct: 73  ----AETGRP--IGILADMQGPKLRIGTFADG---RVVLKNGDRFVL 110


>UniRef50_Q6F1U1 Cluster: Pyruvate kinase; n=10; Mollicutes|Rep:
           Pyruvate kinase - Mesoplasma florum (Acholeplasma
           florum)
          Length = 478

 Score = 60.1 bits (139), Expect = 4e-08
 Identities = 36/99 (36%), Positives = 51/99 (51%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           ++ + II T GP++     + ++ E GM   R+NFSHG +E     I   ++  +    +
Sbjct: 10  VKRTKIITTTGPSTNEPEQIRELFENGMTTIRLNFSHGDYEEQGYRIAGAKKVRE----E 65

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 561
           LG P S  I LDTKGPEIR G     G  EV   +  TI
Sbjct: 66  LGKPVS--ILLDTKGPEIRVGKFV-DGKQEVTANQSITI 101


>UniRef50_Q0AHE3 Cluster: Pyruvate kinase; n=2;
           Nitrosomonadaceae|Rep: Pyruvate kinase - Nitrosomonas
           eutropha (strain C71)
          Length = 483

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 38/102 (37%), Positives = 53/102 (51%), Gaps = 1/102 (0%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGM-NVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSP 456
           IICT+GPA+    VL +++  GM +VAR N SHG H  HA  I+  R+      A+    
Sbjct: 19  IICTLGPATDQPGVLARLIGAGMMDVARFNLSHGDHASHARRIQQVRQL-----AQQAGR 73

Query: 457 FSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
           F +A+ +D  GP+ R G L  G     EL  G  + L   +D
Sbjct: 74  F-IAVLMDLPGPKFRLGELSNGAR---ELHLGADVILALEAD 111


>UniRef50_Q2TSX0 Cluster: Pyruvate kinase; n=2; cellular
           organisms|Rep: Pyruvate kinase - Phaeodactylum
           tricornutum
          Length = 665

 Score = 59.7 bits (138), Expect = 5e-08
 Identities = 31/75 (41%), Positives = 44/75 (58%)
 Frame = +1

Query: 283 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 462
           + T+GPAS N  ++EK+   G +V R+NFSHGS E   E +   RE E+ YS  +G    
Sbjct: 158 VVTLGPASSNKEMIEKLFLAGADVFRLNFSHGSQEQKKELLIMIREVEEKYSHPIG---- 213

Query: 463 LAIALDTKGPEIRTG 507
             I  D +GP++R G
Sbjct: 214 --ILGDLQGPKLRVG 226


>UniRef50_Q63P20 Cluster: Pyruvate kinase; n=74; Proteobacteria|Rep:
           Pyruvate kinase - Burkholderia pseudomallei (Pseudomonas
           pseudomallei)
          Length = 484

 Score = 59.3 bits (137), Expect = 7e-08
 Identities = 30/85 (35%), Positives = 50/85 (58%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+ T+GP+S     +E +   G +V R+NFSHG+H  HA  +R+   A ++  A++
Sbjct: 13  RSTKIVATLGPSSSTETAIEALARAGADVFRLNFSHGTHADHA--LRHA--AVRAIEARI 68

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGG 522
           G P  + + LD +GP++R G    G
Sbjct: 69  GHP--IGVLLDLQGPKLRVGQFASG 91


>UniRef50_A1WED1 Cluster: Pyruvate kinase; n=1; Verminephrobacter
           eiseniae EF01-2|Rep: Pyruvate kinase - Verminephrobacter
           eiseniae (strain EF01-2)
          Length = 496

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 32/85 (37%), Positives = 46/85 (54%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+ T+GPAS   A+LE M+  G+NV R+NFSHG  + H +     R A +      
Sbjct: 23  RATKIVATLGPASSEPALLEAMIRAGVNVVRLNFSHGKAQDHIDRAACVRAAAQR----- 77

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGG 522
            +   +AI  D +GP+IR G    G
Sbjct: 78  -AGHEVAIMADLQGPKIRVGKFAEG 101


>UniRef50_Q8IJ37 Cluster: Pyruvate kinase; n=7; Plasmodium|Rep:
           Pyruvate kinase - Plasmodium falciparum (isolate 3D7)
          Length = 745

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 38/97 (39%), Positives = 50/97 (51%), Gaps = 6/97 (6%)
 Frame = +1

Query: 283 ICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFS 462
           I TIGPAS N   LEK+   G++V R+NFSHG        I + R  EK Y   +G    
Sbjct: 102 IATIGPASENFEQLEKLYLNGIDVFRLNFSHGLKSIKKYIINSIRILEKKYDTTIG---- 157

Query: 463 LAIALDTKGPEIRTG------LLEGGGSAEVELKKGE 555
             I  D +GP+IR G      + E   +  VELK+G+
Sbjct: 158 --ILGDIQGPKIRIGEFEKNQINENDNNTFVELKEGD 192


>UniRef50_Q8ZNW0 Cluster: Pyruvate kinase II; n=173;
           Proteobacteria|Rep: Pyruvate kinase II - Salmonella
           typhimurium
          Length = 480

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 37/89 (41%), Positives = 49/89 (55%)
 Frame = +1

Query: 256 SSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSY 435
           S  +R + I+ T+GPA+     LEK++  G NV RMNFSHGS E H       RE     
Sbjct: 2   SRRLRRTKIVTTLGPATDRDNNLEKVIAAGANVVRMNFSHGSPEDHKMRADKVRE----I 57

Query: 436 SAKLGSPFSLAIALDTKGPEIRTGLLEGG 522
           +AKLG    +AI  D +GP+IR    + G
Sbjct: 58  AAKLGR--HVAILGDLQGPKIRVSTFKEG 84


>UniRef50_Q1ZJ78 Cluster: Pyruvate kinase; n=1; Psychromonas sp.
           CNPT3|Rep: Pyruvate kinase - Psychromonas sp. CNPT3
          Length = 485

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 28/74 (37%), Positives = 48/74 (64%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           II T+GPAS++  ++ K++  G+N+ R+NFSHGS + H +    C +  +  SA+LG   
Sbjct: 6   IIATLGPASQSEDMIRKLILAGVNIVRLNFSHGSAQEHID----CAKLVRRISAELGK-- 59

Query: 460 SLAIALDTKGPEIR 501
            + + +D +GP+IR
Sbjct: 60  YVGVLVDLQGPKIR 73


>UniRef50_Q1MPC8 Cluster: Pyruvate kinase; n=4;
           Desulfovibrionaceae|Rep: Pyruvate kinase - Lawsonia
           intracellularis (strain PHE/MN1-00)
          Length = 471

 Score = 57.2 bits (132), Expect = 3e-07
 Identities = 33/96 (34%), Positives = 49/96 (51%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           II TIGPAS +   L ++++ G+++ R+NFSHG      E I   RE E  +        
Sbjct: 5   IIATIGPASNSKETLSQLIQAGVSIFRLNFSHGDSSAFIELISTIRELEHIHQ------I 58

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
            + I  D  GP+IR G L   G   + + KG+ + L
Sbjct: 59  PITIMQDLSGPKIRIGALP--GDVALNVSKGDVLCL 92


>UniRef50_A1IEN3 Cluster: Pyruvate kinase; n=1; Candidatus
           Desulfococcus oleovorans Hxd3|Rep: Pyruvate kinase -
           Candidatus Desulfococcus oleovorans Hxd3
          Length = 478

 Score = 56.0 bits (129), Expect = 6e-07
 Identities = 33/96 (34%), Positives = 53/96 (55%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           +I TIGP SR+ AV+EK++  G+ + R+NFSH      A+ I++ RE E+          
Sbjct: 5   LIATIGPRSRDRAVIEKLVAVGVTIFRLNFSHAGPGDFADVIQSVREIEQQTGT------ 58

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
            L +  D  GP+IR G + G   A + +  G+ ++L
Sbjct: 59  ILTLMGDLSGPKIRIGEVAG---APLSVATGQLVRL 91


>UniRef50_Q7QVW2 Cluster: Pyruvate kinase; n=1; Giardia lamblia ATCC
           50803|Rep: Pyruvate kinase - Giardia lamblia ATCC 50803
          Length = 553

 Score = 55.6 bits (128), Expect = 8e-07
 Identities = 32/108 (29%), Positives = 56/108 (51%)
 Frame = +1

Query: 244 IDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREA 423
           +D    +     I CT+GP+S NV V+  M+  G ++ R+NFSHG+ + H +     ++A
Sbjct: 30  VDKNHPHFNRVKICCTLGPSSFNVEVIAGMIRAGADIIRINFSHGNTDDHTQIFHKVQQA 89

Query: 424 EKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
               + K     ++AI  D +GP++R        +  +ELK+G+   L
Sbjct: 90  -MQLTGK-----TVAIMGDIQGPKLRIAGFSNPDNC-IELKEGQEFTL 130


>UniRef50_Q7P1G4 Cluster: Pyruvate kinase; n=4; Bacteria|Rep:
           Pyruvate kinase - Chromobacterium violaceum
          Length = 468

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 26/81 (32%), Positives = 47/81 (58%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+ T+GP+S     + ++  +G+N+ R+N SHGSH+ H   +   R AEK+    
Sbjct: 2   LRNTKILATLGPSSSAPEKILELARSGVNIFRLNMSHGSHDDHRARLAAIRAAEKTLDRP 61

Query: 445 LGSPFSLAIALDTKGPEIRTG 507
           +G      + +D +GP++R G
Sbjct: 62  IG------VLVDLQGPKLRIG 76


>UniRef50_A4APL1 Cluster: Pyruvate kinase; n=15; Bacteroidetes|Rep:
           Pyruvate kinase - Flavobacteriales bacterium HTCC2170
          Length = 480

 Score = 54.4 bits (125), Expect = 2e-06
 Identities = 31/107 (28%), Positives = 57/107 (53%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           I+ + I+ T+GPA+    V+  M++ G++V R+NFSH  +E     ++  RE  +   + 
Sbjct: 4   IKKTKIVATLGPATSKKEVIIDMIKAGVDVFRINFSHADYEDVTARVKMIREVNEEIDS- 62

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 585
                ++AI  D +GP++R G++ G    EV +  G+ I   T   +
Sbjct: 63  -----NIAILGDLQGPKLRVGVMSG----EVVVTPGDEIDFVTGEPF 100


>UniRef50_A7QH42 Cluster: Chromosome chr3 scaffold_95, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr3 scaffold_95, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 573

 Score = 54.0 bits (124), Expect = 2e-06
 Identities = 31/107 (28%), Positives = 59/107 (55%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + ++CTIGPA   +  LE +  +GMNVAR+N  H + E+H + IR  +   +     
Sbjct: 87  MRKTKLVCTIGPACCLLEDLENLASSGMNVARLNMCHNTWEWHRDVIRKIKRLNEE---- 142

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSDY 585
               + +++ +DT+G +I   +++ G    V+  + E+I L T+  +
Sbjct: 143 --KGYCVSVMIDTEGGQIH--VVDHGAPFSVK-AENESIWLFTTQKF 184


>UniRef50_Q6L281 Cluster: Pyruvate kinase; n=2;
           Thermoplasmatales|Rep: Pyruvate kinase - Picrophilus
           torridus
          Length = 555

 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 28/90 (31%), Positives = 50/90 (55%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           +I TIGPAS ++ +++KM   G++  R+N +H  + Y  +  +   +  KS    +G   
Sbjct: 6   LIATIGPASESMEIIKKMANLGLSCIRINTAHIENGYITKVAKMVDDVNKSEGTYIG--- 62

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKK 549
              + +D KGPE+RTG  +  GS +++  K
Sbjct: 63  ---LMVDLKGPELRTGKFK-DGSFKIDYNK 88


>UniRef50_P78031 Cluster: Pyruvate kinase; n=6; Mycoplasma|Rep:
           Pyruvate kinase - Mycoplasma pneumoniae
          Length = 508

 Score = 52.4 bits (120), Expect = 8e-06
 Identities = 35/89 (39%), Positives = 48/89 (53%)
 Frame = +1

Query: 316 AVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPE 495
           A +E +++ G+ V R+NFSHG+HE  A  I+  R+  K    KL  P S  I LDT GPE
Sbjct: 42  ANIENIIKNGVTVIRLNFSHGNHEEQAVRIKIVRDVAK----KLNLPVS--IMLDTNGPE 95

Query: 496 IRTGLLEGGGSAEVELKKGETIKLTTSSD 582
           IR  + E        LK  E +  TT+ +
Sbjct: 96  IR--VFETAPEGLKILKDSEVVINTTTKE 122


>UniRef50_Q0PQH4 Cluster: Pyruvate kinase; n=1; Endoriftia
           persephone 'Hot96_1+Hot96_2'|Rep: Pyruvate kinase -
           Endoriftia persephone 'Hot96_1+Hot96_2'
          Length = 246

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 24/80 (30%), Positives = 45/80 (56%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+ T+GPA+ +  V++K++  G++V R+N SH  H+   E     R+  ++   ++
Sbjct: 36  RRTKIVATLGPATDDPKVMDKLIHAGVDVVRLNLSHDPHDQQRERAERIRDRSRASGRQV 95

Query: 448 GSPFSLAIALDTKGPEIRTG 507
           G      +  D +GP+IR G
Sbjct: 96  G------VLCDLQGPKIRIG 109


>UniRef50_Q07637 Cluster: Pyruvate kinase; n=44;
           Streptococcaceae|Rep: Pyruvate kinase - Lactococcus
           lactis subsp. lactis (Streptococcus lactis)
          Length = 502

 Score = 52.0 bits (119), Expect = 1e-05
 Identities = 32/91 (35%), Positives = 46/91 (50%)
 Frame = +1

Query: 301 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 480
           +++N+A L   +E G NV R NFSHG H      +     AE+    K+G        LD
Sbjct: 38  SAKNIAAL---IEEGANVFRFNFSHGDHPEQGARMATVHRAEEIAGHKVG------FLLD 88

Query: 481 TKGPEIRTGLLEGGGSAEVELKKGETIKLTT 573
           TKGPE+RT L   G  A + +  G+  ++ T
Sbjct: 89  TKGPEMRTELFADGADA-ISVVTGDKFRVAT 118


>UniRef50_UPI0000D56D72 Cluster: PREDICTED: similar to CG7070-PB,
           isoform B; n=1; Tribolium castaneum|Rep: PREDICTED:
           similar to CG7070-PB, isoform B - Tribolium castaneum
          Length = 535

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 33/122 (27%), Positives = 59/122 (48%)
 Frame = +1

Query: 220 LQHMCGLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAE 399
           L+H+  L   S+    RL+     I P   ++  +E+ ++ GM VA +   + + +   E
Sbjct: 44  LEHLARLQEKSRVRRKRLTQFSVIIPPRI-SIEHIEEFLKAGMTVALIRMDYFTVDEIEE 102

Query: 400 TIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 579
            +   R     +  K+G  + +AI LD    EI+TG L      E+EL+KG+T K+    
Sbjct: 103 MVAMIRNVVDDFGKKIGRVYPIAIGLDVSEQEIKTGKLL-KPLKEIELEKGQTTKIVAKP 161

Query: 580 DY 585
           ++
Sbjct: 162 EF 163


>UniRef50_A5JEK8 Cluster: Pyruvate kinase; n=1; Nosema bombycis|Rep:
           Pyruvate kinase - Nosema bombycis
          Length = 441

 Score = 51.6 bits (118), Expect = 1e-05
 Identities = 31/97 (31%), Positives = 53/97 (54%)
 Frame = +1

Query: 271 LSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLG 450
           ++ II T+   S +   L   ++ G+++ R+N SHG+   H  +I N R+  K    ++G
Sbjct: 5   MTKIIVTVSSVSDDEETLTNFLKEGVHIFRINLSHGTSYQHEHSILNIRKCAK----EMG 60

Query: 451 SPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 561
                 I LDT+GPE+R  + E    +E+ LK+G+ I
Sbjct: 61  --IVPVICLDTRGPEVRIEIAE---RSEIPLKEGDKI 92


>UniRef50_Q9PF54 Cluster: Pyruvate kinase; n=11;
           Xanthomonadaceae|Rep: Pyruvate kinase - Xylella
           fastidiosa
          Length = 501

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 29/85 (34%), Positives = 41/85 (48%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+ T+GPA+    VL+ + + G+NV R+NFSHG     A      R A      ++
Sbjct: 19  RRTRILATLGPATDPPGVLDALFKAGVNVVRLNFSHGDASDQARRAAEVRAAAAHVGVEI 78

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGG 522
           G      I  D  GP+IR G    G
Sbjct: 79  G------ILADLPGPKIRIGRFTEG 97


>UniRef50_A3DMY9 Cluster: Pyruvate kinase; n=1; Staphylothermus
           marinus F1|Rep: Pyruvate kinase - Staphylothermus
           marinus (strain ATCC 43588 / DSM 3639 / F1)
          Length = 469

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 32/96 (33%), Positives = 52/96 (54%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           II TIGP+S    VL ++++ G++  R+NFSHG+     E ++  RE  + Y  +     
Sbjct: 6   IITTIGPSSGKYEVLSRLIQEGVDGFRINFSHGNPHEWDEWVKMVRELAEKYERE----- 60

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
            ++I  D  GP++R G L        E+K  +T+KL
Sbjct: 61  -ISIMGDLPGPQVRIGEL-----PVQEIKAKQTVKL 90


>UniRef50_O05118 Cluster: Pyruvate kinase; n=44; Proteobacteria|Rep:
           Pyruvate kinase - Methylobacterium extorquens
           (Protomonas extorquens)
          Length = 483

 Score = 50.4 bits (115), Expect = 3e-05
 Identities = 32/100 (32%), Positives = 50/100 (50%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           R + I+ T+GPAS    ++EK+   G +V R+N SH + E   E I   R  E+     +
Sbjct: 10  RRTKIVATLGPASDTPEMIEKLFHAGADVFRINMSHLAREKLPERIEVIRTIEREGKRPI 69

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKL 567
           G      I +D +GP++R G   G  +    L+ G+T  L
Sbjct: 70  G------ILVDLQGPKLRLGTFVGDAAV---LENGQTFVL 100


>UniRef50_A3ZTM3 Cluster: Pyruvate kinase; n=1; Blastopirellula
           marina DSM 3645|Rep: Pyruvate kinase - Blastopirellula
           marina DSM 3645
          Length = 490

 Score = 49.6 bits (113), Expect = 5e-05
 Identities = 28/78 (35%), Positives = 42/78 (53%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+ T+GPA     +LE+M+  G++V R+N +HG  + H+      RE     S +L  P 
Sbjct: 15  IVATVGPACNTPEMLEQMILAGVDVFRLNLAHGELDEHSRVATTIRE----ISERLKRP- 69

Query: 460 SLAIALDTKGPEIRTGLL 513
            +A   D  GP+IR G L
Sbjct: 70  -VATLADLSGPKIRLGTL 86


>UniRef50_A3ALA5 Cluster: Pyruvate kinase; n=3; Oryza sativa|Rep:
           Pyruvate kinase - Oryza sativa subsp. japonica (Rice)
          Length = 548

 Score = 49.6 bits (113), Expect = 5e-05
 Identities = 28/96 (29%), Positives = 50/96 (52%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + ++CT+GPA   V  L  +   GM VAR+N  HG   +H   +R  R   +     
Sbjct: 62  LRKTKLVCTVGPAC--VGALPALARGGMGVARVNLCHGGRGWHRAVMREVRRLNEE---- 115

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKG 552
               F +++ +DT+G ++   + + GG+A V+ + G
Sbjct: 116 --EGFCVSLMVDTEGSQLL--VADHGGAASVKAEDG 147


>UniRef50_Q8EWX2 Cluster: Pyruvate kinase; n=1; Mycoplasma
           penetrans|Rep: Pyruvate kinase - Mycoplasma penetrans
          Length = 498

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 32/95 (33%), Positives = 47/95 (49%)
 Frame = +1

Query: 292 IGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAI 471
           I  A +N+A L    + G+NV R NFSHG +E     +   RE  K          +++ 
Sbjct: 36  IETAKKNLAAL---FDAGVNVVRFNFSHGDYEEQTIRLNLVREVAKEKGV------NIST 86

Query: 472 ALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTS 576
            LDTKGPEIR   +      EVE+K    +++ T+
Sbjct: 87  MLDTKGPEIR---VYKTSEKEVEIKSDSKVRIYTT 118


>UniRef50_Q5ZZ75 Cluster: Pyruvate kinase II; n=4; Legionella
           pneumophila|Rep: Pyruvate kinase II - Legionella
           pneumophila subsp. pneumophila (strain Philadelphia 1
           /ATCC 33152 / DSM 7513)
          Length = 474

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 28/81 (34%), Positives = 45/81 (55%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+ T+GPAS+   +L  M+  G+NV R+NFSH       + I   R+     + +
Sbjct: 2   LRRTKIVATLGPASKEPEILRSMLAAGVNVVRINFSHADSS-ALQLIALVRK----IADE 56

Query: 445 LGSPFSLAIALDTKGPEIRTG 507
           L  P  +A+  D +GP+IR G
Sbjct: 57  LNHP--VAVMADLQGPKIRVG 75


>UniRef50_A7APT5 Cluster: Pyruvate kinase family protein; n=1;
           Babesia bovis|Rep: Pyruvate kinase family protein -
           Babesia bovis
          Length = 693

 Score = 48.0 bits (109), Expect = 2e-04
 Identities = 34/122 (27%), Positives = 57/122 (46%), Gaps = 15/122 (12%)
 Frame = +1

Query: 253 KSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKS 432
           +  ++ L+  + T+GP++     L  +ME G ++ R+NFSHG+  +     R  R+ E  
Sbjct: 105 QGQFMTLTKQVSTLGPSTCTADSLRSIMEAGTDIYRLNFSHGTRLFKLRLTRMIRQLELV 164

Query: 433 YSAKLGSPFSL----AIALDTKGPEIRTGL-----------LEGGGSAEVELKKGETIKL 567
            S+  GS   +     I  D +GP++R G            +E   +  VELKKG+    
Sbjct: 165 RSSGEGSDSFMVSPKGILGDIQGPKLRIGRFMPNVDAVGKGIESSAAEFVELKKGDKFTF 224

Query: 568 TT 573
            T
Sbjct: 225 DT 226


>UniRef50_A2BLH1 Cluster: Pyruvate kinase; n=1; Hyperthermus
           butylicus DSM 5456|Rep: Pyruvate kinase - Hyperthermus
           butylicus (strain DSM 5456 / JCM 9403)
          Length = 466

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 30/76 (39%), Positives = 42/76 (55%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           II +IGP+S +  V+ ++ E G++  R+NF+HG      E     REAE+    K G P 
Sbjct: 8   IIASIGPSSGSPEVILRLAELGVSGFRINFAHGEPSLWREWAEYVREAER----KTGRP- 62

Query: 460 SLAIALDTKGPEIRTG 507
            LA+  D  GP IR G
Sbjct: 63  -LALIGDLVGPSIRLG 77


>UniRef50_P32044 Cluster: Pyruvate kinase; n=2; Thermoplasma|Rep:
           Pyruvate kinase - Thermoplasma acidophilum
          Length = 544

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 25/81 (30%), Positives = 46/81 (56%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+ TIGPAS +  ++++M++ G+++ R+N +H       + +    +  +S +  +G   
Sbjct: 5   IVATIGPASSSPEIMKQMIDNGLSLVRINSAHAD----IKDVSKITQMVRSINRDVG--- 57

Query: 460 SLAIALDTKGPEIRTGLLEGG 522
              I +D KGPE+RTG   GG
Sbjct: 58  ---IMIDLKGPELRTGEFAGG 75


>UniRef50_O51323 Cluster: Pyruvate kinase; n=5; cellular
           organisms|Rep: Pyruvate kinase - Borrelia burgdorferi
           (Lyme disease spirochete)
          Length = 477

 Score = 47.6 bits (108), Expect = 2e-04
 Identities = 30/103 (29%), Positives = 53/103 (51%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           +L+ I+ TI         ++ + + G+NV R+N +H SHE   + I N R+         
Sbjct: 4   KLTKIVATISDLRCEPEHIKDLHDAGVNVIRLNTAHQSHEDTIKVIDNVRKISN------ 57

Query: 448 GSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTS 576
                +A+ +DTKGPE+RT  +E      + +K G+ + ++TS
Sbjct: 58  ----KIALMIDTKGPEVRTANIEN----PIIVKTGDKVIISTS 92


>UniRef50_A6LH43 Cluster: Pyruvate kinase; n=2; Parabacteroides|Rep:
           Pyruvate kinase - Parabacteroides distasonis (strain
           ATCC 8503 / DSM 20701 / NCTC11152)
          Length = 485

 Score = 46.8 bits (106), Expect = 4e-04
 Identities = 31/101 (30%), Positives = 49/101 (48%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+ T+     +VA +E + + GMNV R+N +H   E     + N R    + S ++G   
Sbjct: 7   IVATVSDQRCDVAFVEALYKAGMNVVRLNTAHMMEEGLTRVVNNVR----TVSDRIG--- 59

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
              I +DTKGPE+RT          +  K GE +K+  + D
Sbjct: 60  ---ILMDTKGPEVRTTTTV--NKEPIPFKTGEIVKVIGNPD 95


>UniRef50_Q64MR8 Cluster: Pyruvate kinase; n=6; Bacteroides|Rep:
           Pyruvate kinase - Bacteroides fragilis
          Length = 485

 Score = 45.6 bits (103), Expect = 9e-04
 Identities = 26/80 (32%), Positives = 41/80 (51%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           ++ + I+ +I     +V  ++++ + GMNV RMN +H S E     I N R         
Sbjct: 3   LKQTKIVASISDRRCDVDFIKELFDAGMNVVRMNTAHASREGFEALIANVRAVSN----- 57

Query: 445 LGSPFSLAIALDTKGPEIRT 504
                 +AI +DTKGPE+RT
Sbjct: 58  -----RIAILMDTKGPEVRT 72


>UniRef50_UPI00006CE5D4 Cluster: pyruvate kinase family protein;
           n=1; Tetrahymena thermophila SB210|Rep: pyruvate kinase
           family protein - Tetrahymena thermophila SB210
          Length = 495

 Score = 45.2 bits (102), Expect = 0.001
 Identities = 17/37 (45%), Positives = 29/37 (78%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHG 378
           R + I+CT+GP S +V ++ K++++GMNVAR+ + HG
Sbjct: 22  RKTKIVCTLGPQSSSVEMICKLLDSGMNVARITYCHG 58


>UniRef50_A3PTF7 Cluster: Pyruvate kinase; n=5; Mycobacterium|Rep:
           Pyruvate kinase - Mycobacterium sp. (strain JLS)
          Length = 615

 Score = 44.8 bits (101), Expect = 0.002
 Identities = 31/108 (28%), Positives = 53/108 (49%), Gaps = 1/108 (0%)
 Frame = +1

Query: 202 ANVGSQLQHMCGLDIDSKSSYIRLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHG 378
           ANVG +L     +D+   +   R + I+ T+   A+ +  ++  ++  GMNVAR+N +H 
Sbjct: 116 ANVGDELLREHAVDLFGPAPAERATRIMVTLPSSAATDPDLVRDLIARGMNVARINCAHD 175

Query: 379 SHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTGLLEGG 522
             E       + R A +S   K        +A+D  GP++RTG +  G
Sbjct: 176 DAEAWTAMAGHVRRAAESTGRK------CLVAMDLAGPKLRTGPIRPG 217


>UniRef50_A4ARB8 Cluster: Pyruvate kinase; n=1; Flavobacteriales
           bacterium HTCC2170|Rep: Pyruvate kinase -
           Flavobacteriales bacterium HTCC2170
          Length = 624

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 28/86 (32%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
 Frame = +1

Query: 268 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           R + I+ T+   A+ ++  + K++  GMN AR+N +H + E   + I N + A K    K
Sbjct: 131 RFTRIMVTLPNTAAEDLGFIRKLLANGMNCARINCAHDTPEDWLKMIDNLKIASKRQRKK 190

Query: 445 LGSPFSLAIALDTKGPEIRTG-LLEG 519
                   IA+D  GP++RTG ++EG
Sbjct: 191 ------CKIAMDLSGPKLRTGPMVEG 210


>UniRef50_A7QTW5 Cluster: Chromosome undetermined scaffold_171,
           whole genome shotgun sequence; n=1; Vitis vinifera|Rep:
           Chromosome undetermined scaffold_171, whole genome
           shotgun sequence - Vitis vinifera (Grape)
          Length = 622

 Score = 43.6 bits (98), Expect = 0.004
 Identities = 29/105 (27%), Positives = 55/105 (52%), Gaps = 1/105 (0%)
 Frame = +1

Query: 268 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           R + I+ T+G   + N  ++  ++++G  + R+N +HG+    +E IR  R +    S  
Sbjct: 258 RTAHIMVTVGQEVTENETLITDILKSGATIIRINCAHGNPSIWSEIIRRVRRS----SQM 313

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 579
           L  P    I +D  GP++RTG ++  G   V L+ G+ + ++  S
Sbjct: 314 LEKP--CRILMDLAGPKLRTGNMK-AGPCFVRLRVGDLLIISLDS 355


>UniRef50_A7PC98 Cluster: Chromosome chr2 scaffold_11, whole genome
           shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
           chr2 scaffold_11, whole genome shotgun sequence - Vitis
           vinifera (Grape)
          Length = 475

 Score = 43.2 bits (97), Expect = 0.005
 Identities = 27/78 (34%), Positives = 41/78 (52%), Gaps = 6/78 (7%)
 Frame = +1

Query: 370 SHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG------LLEGGGSA 531
           SHG H  H +TI   +E    +  K+     +AI LDTKGPE+R+G      +L+ G   
Sbjct: 2   SHGDHASHKKTIDLVKEYNAQFEDKV-----IAIMLDTKGPEVRSGDVPKPIMLKEGQEF 56

Query: 532 EVELKKGETIKLTTSSDY 585
              +K+G + + T S +Y
Sbjct: 57  NFTIKRGVSSENTVSVNY 74


>UniRef50_A6LTB0 Cluster: Pyruvate kinase; n=1; Clostridium
           beijerinckii NCIMB 8052|Rep: Pyruvate kinase -
           Clostridium beijerinckii NCIMB 8052
          Length = 340

 Score = 42.7 bits (96), Expect = 0.006
 Identities = 20/56 (35%), Positives = 33/56 (58%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKL 447
           II T+GP  ++ AVL+ ++E+G+N  R NF HGS E   E ++  ++ +      L
Sbjct: 3   IIGTVGPNVKDRAVLKGIIESGVNALRFNFIHGSAEEFLEFLKMAKDIKSDIQVML 58


>UniRef50_A1RX09 Cluster: Pyruvate kinase; n=1; Thermofilum pendens
           Hrk 5|Rep: Pyruvate kinase - Thermofilum pendens (strain
           Hrk 5)
          Length = 464

 Score = 42.3 bits (95), Expect = 0.008
 Identities = 27/100 (27%), Positives = 47/100 (47%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           ++ T+GP+S +   +++M+  G+N  R+NFSH  +    E  +  R  E           
Sbjct: 6   LVATLGPSSWSEETMKRMVAEGVNAFRLNFSHVDYARFEELAKQVRRLETPLR------- 58

Query: 460 SLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSS 579
            L +  D +GP IR G       A  +++ G+ +  T SS
Sbjct: 59  PLTLIADLQGPVIRLGEF-----APFQVRPGDRVTFTLSS 93


>UniRef50_Q5KVI2 Cluster: Pyruvate kinase; n=2; Geobacillus|Rep:
           Pyruvate kinase - Geobacillus kaustophilus
          Length = 660

 Score = 41.9 bits (94), Expect = 0.011
 Identities = 32/113 (28%), Positives = 55/113 (48%), Gaps = 2/113 (1%)
 Frame = +1

Query: 217 QLQHMCGLDIDSKSSYIRLSGIICTIGPA-SRNVAVLEKMMETGMNVARMNFSHGSHEYH 393
           QL H     +    S +R + I+ T+  A      ++E+++  GM++AR+N ++GS E  
Sbjct: 154 QLLHKRAEAVFGSPSSVRPTRIMVTMDEAWVDEPGLIERLLLYGMDIARINCAYGSPETW 213

Query: 394 AETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIRTG-LLEGGGSAEVELKK 549
              +   R+AEK    +L       I +D  GP+IR   L    G  ++ +KK
Sbjct: 214 EALVAIIRQAEKQLEQQLQGR-RCRIYMDLPGPKIRVDRLAVNAGPMKLSVKK 265


>UniRef50_A1U5Q4 Cluster: Pyruvate kinase; n=2; Marinobacter
           aquaeolei VT8|Rep: Pyruvate kinase - Marinobacter
           aquaeolei (strain ATCC 700491 / DSM 11845 /
           VT8)(Marinobacter hydrocarbonoclasticus (strain DSM
           11845))
          Length = 626

 Score = 41.5 bits (93), Expect = 0.014
 Identities = 21/74 (28%), Positives = 41/74 (55%)
 Frame = +1

Query: 301 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 480
           ++++ +++  +++ GMN  R+N +H   E   E I N + A++ +        S  + +D
Sbjct: 154 SAQDPSIIRDLLKAGMNCMRINCAHDDPETWLEMINNLQTAKEEFGQ------SCQVFMD 207

Query: 481 TKGPEIRTGLLEGG 522
             GP+IRTG +E G
Sbjct: 208 LGGPKIRTGEIEPG 221


>UniRef50_Q2JJ60 Cluster: Pyruvate kinase; n=5; Bacteria|Rep:
           Pyruvate kinase - Synechococcus sp. (strain
           JA-2-3B'a(2-13)) (Cyanobacteria bacteriumYellowstone
           B-Prime)
          Length = 476

 Score = 40.7 bits (91), Expect = 0.025
 Identities = 30/102 (29%), Positives = 52/102 (50%), Gaps = 1/102 (0%)
 Frame = +1

Query: 268 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           R + I+ T+   A+    +L +++E GMNVAR+N +H       + + + R+AE     +
Sbjct: 118 RRARIMVTLPSEAAEQPELLLQLLERGMNVARINCAHDEPSVWEKMVAHLRQAEAQTQRR 177

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
                   I LD  GP+IRTG +      + ++ +G+ I LT
Sbjct: 178 ------CKILLDLAGPKIRTGPV-AMPPGKTKVYRGDRILLT 212


>UniRef50_Q4IUP8 Cluster: Pyruvate kinase; n=1; Azotobacter
           vinelandii AvOP|Rep: Pyruvate kinase - Azotobacter
           vinelandii AvOP
          Length = 165

 Score = 40.7 bits (91), Expect = 0.025
 Identities = 18/51 (35%), Positives = 29/51 (56%)
 Frame = +1

Query: 268 RLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCRE 420
           R + I+ T+G A+     +E +++ G++V R+NFSHG  E H       RE
Sbjct: 3   RRTKIVATLGSATETPEAIEGLVKAGVDVVRLNFSHGKAEEHQARATLVRE 53


>UniRef50_Q4N603 Cluster: Pyruvate kinase; n=2; Theileria|Rep:
           Pyruvate kinase - Theileria parva
          Length = 699

 Score = 40.3 bits (90), Expect = 0.033
 Identities = 27/87 (31%), Positives = 46/87 (52%), Gaps = 6/87 (6%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSH-EYH--AETIR--NCREAEK 429
           + L+  + T+GPA+ N   ++ + + G++V R+NFSH S    H  ++TIR     E  K
Sbjct: 116 LTLTKQVATLGPATNNAESIKSLFDAGVDVFRLNFSHDSRLSKHLVSKTIRQLEINEPPK 175

Query: 430 SYSAKLGSPFS-LAIALDTKGPEIRTG 507
           +Y           +I  D +GP++R G
Sbjct: 176 NYPFNGDHVVEHKSILGDIQGPKLRIG 202


>UniRef50_A4VPY3 Cluster: Pyruvate kinase; n=1; Pseudomonas stutzeri
           A1501|Rep: Pyruvate kinase - Pseudomonas stutzeri
           (strain A1501)
          Length = 625

 Score = 39.9 bits (89), Expect = 0.043
 Identities = 24/69 (34%), Positives = 39/69 (56%)
 Frame = +1

Query: 301 ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALD 480
           A+ N  ++E +++ GM+ AR+N +H   +     I + R AEK+    LG      +ALD
Sbjct: 150 AAHNRDLIEALIKEGMDCARINCAHDDPDSWRAMIEHVRAAEKA----LGR--ECKVALD 203

Query: 481 TKGPEIRTG 507
             GP++RTG
Sbjct: 204 LAGPKLRTG 212


>UniRef50_Q7NJ33 Cluster: Pyruvate kinase; n=1; Gloeobacter
           violaceus|Rep: Pyruvate kinase - Gloeobacter violaceus
          Length = 501

 Score = 38.3 bits (85), Expect = 0.13
 Identities = 30/106 (28%), Positives = 50/106 (47%), Gaps = 1/106 (0%)
 Frame = +1

Query: 268 RLSGIICTI-GPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           R + I+ T+   A  +  +L  ++  GMN AR+N  H S       + N R AE+     
Sbjct: 142 RATRIMVTLPSEAEGDYRLLCALIRAGMNCARINCVHDSETVWERMVGNIRRAEREVGR- 200

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLTTSSD 582
                +  I +D  GP++RTG L    +  + L+KGE + L   ++
Sbjct: 201 -----ACRILMDLGGPKLRTGPL----AEPLTLRKGEGLVLCRDAE 237


>UniRef50_Q9M3B6 Cluster: Pyruvate kinase; n=1; Arabidopsis
           thaliana|Rep: Pyruvate kinase - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 710

 Score = 37.1 bits (82), Expect = 0.30
 Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
 Frame = +1

Query: 268 RLSGIICTIGP-ASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           R + I+ TIG  A+ +   +  +++ G +V R+N +HG      E I+  R      S  
Sbjct: 234 RSTHIMVTIGEEATLSETFITDILKAGTSVIRINCAHGDPSIWGEIIKRVRRT----SQM 289

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGG 522
           L  P    + +D  GP++RTG L+ G
Sbjct: 290 LEMP--CRVHMDLAGPKLRTGTLKPG 313


>UniRef50_Q9PQV7 Cluster: Pyruvate kinase; n=1; Ureaplasma
           parvum|Rep: Pyruvate kinase - Ureaplasma parvum
           (Ureaplasma urealyticum biotype 1)
          Length = 474

 Score = 35.5 bits (78), Expect = 0.93
 Identities = 19/60 (31%), Positives = 31/60 (51%)
 Frame = +1

Query: 322 LEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPFSLAIALDTKGPEIR 501
           ++ ++ +G+N+ RMN SHG  + H    +  ++       K      + I  DTKGPEIR
Sbjct: 41  IKDLILSGVNIFRMNLSHGDQKIHLFRTQLIKKIADELKIK------VEILFDTKGPEIR 94


>UniRef50_Q97ZD7 Cluster: Pyruvate kinase; n=4; Sulfolobaceae|Rep:
           Pyruvate kinase - Sulfolobus solfataricus
          Length = 452

 Score = 35.5 bits (78), Expect = 0.93
 Identities = 30/99 (30%), Positives = 52/99 (52%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           +R + I+ T+GP+S       K +   ++V R+NF+HG    H    R   +  ++Y   
Sbjct: 1   MRKTKIVATLGPSSEEKV---KELAEYVDVFRINFAHGDETSH----RKYFDLIRTY--- 50

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETI 561
             +P S +I +D  GP++R G L+      +E+KKG+ I
Sbjct: 51  --APES-SIIVDLPGPKLRLGELK----EPIEVKKGDKI 82


>UniRef50_A2STG1 Cluster: Putative anti-sigma regulatory factor,
           serine/threonine protein kinase; n=1; Methanocorpusculum
           labreanum Z|Rep: Putative anti-sigma regulatory factor,
           serine/threonine protein kinase - Methanocorpusculum
           labreanum (strain ATCC 43576 / DSM 4855 / Z)
          Length = 777

 Score = 35.1 bits (77), Expect = 1.2
 Identities = 17/48 (35%), Positives = 25/48 (52%)
 Frame = +1

Query: 235 GLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHG 378
           G  ID K +YI+ SG+IC  G A   + V +KM   G  +    ++ G
Sbjct: 349 GTGIDVKGTYIQNSGMICGTGMAGDGICVAKKMTVYGGKIEATGYTTG 396


>UniRef50_A6PU80 Cluster: Pyruvate kinase; n=1; Victivallis vadensis
           ATCC BAA-548|Rep: Pyruvate kinase - Victivallis vadensis
           ATCC BAA-548
          Length = 121

 Score = 34.7 bits (76), Expect = 1.6
 Identities = 29/102 (28%), Positives = 48/102 (47%)
 Frame = +1

Query: 265 IRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAK 444
           ++ + I+ TI  ++    +L  + + GM+V R+N +H         +   R+        
Sbjct: 1   MKYTKIVATINASTCTEELLRGLYKNGMDVVRLNTAHMEIADMDRIVALVRKVSDK---- 56

Query: 445 LGSPFSLAIALDTKGPEIRTGLLEGGGSAEVELKKGETIKLT 570
                 LAI +DTKGP IRT  L+    A + LK G+ + LT
Sbjct: 57  ------LAIMVDTKGPNIRTCNLD----APLALKIGDKLDLT 88


>UniRef50_A5NL17 Cluster: ATP-dependent Clp protease, ATP-binding
           subunit ClpA; n=1; Shewanella baltica OS223|Rep:
           ATP-dependent Clp protease, ATP-binding subunit ClpA -
           Shewanella baltica OS223
          Length = 66

 Score = 34.3 bits (75), Expect = 2.2
 Identities = 20/51 (39%), Positives = 29/51 (56%), Gaps = 4/51 (7%)
 Frame = +1

Query: 421 AEKSYSAKLGS-PFSLAIALDTKGP---EIRTGLLEGGGSAEVELKKGETI 561
           AEK Y   +G+ P +  +    K P   EI  G+LE GG A V++K+GE +
Sbjct: 3   AEKGYDKNMGARPMARVVTELIKRPLADEILFGVLESGGVAHVDVKEGELV 53


>UniRef50_Q9V2V8 Cluster: Pyruvate kinase; n=1; Thermoproteus
           tenax|Rep: Pyruvate kinase - Thermoproteus tenax
          Length = 446

 Score = 33.5 bits (73), Expect = 3.8
 Identities = 22/78 (28%), Positives = 39/78 (50%)
 Frame = +1

Query: 280 IICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSAKLGSPF 459
           I+ T+GP++  +  +  ++     V R+N SH S       +   R+ E++      S  
Sbjct: 5   IVATLGPSTDRLPDITALLSKVHGV-RINMSHASPSEVEARVNAVRKYEET------SGR 57

Query: 460 SLAIALDTKGPEIRTGLL 513
            +AI  D +GP +RTGL+
Sbjct: 58  YIAIIADLRGPSVRTGLM 75


>UniRef50_A5BAI3 Cluster: Putative uncharacterized protein; n=2;
           Vitis vinifera|Rep: Putative uncharacterized protein -
           Vitis vinifera (Grape)
          Length = 929

 Score = 33.1 bits (72), Expect = 5.0
 Identities = 29/102 (28%), Positives = 40/102 (39%)
 Frame = +1

Query: 136 KMVYPTIHDGEIEAGAVEKPTVANVGSQLQHMCGLDIDSKSSYIRLSGIICTIGPASRNV 315
           K + PT++DG  + G    PT ++ GS +     +   S  SY  L  ++  I P S   
Sbjct: 694 KEIQPTVNDGAPDPGEESHPTASSGGSPVDDATCISA-SPFSYTELGEMLKRIPPGSDVA 752

Query: 316 AVLEKMMETGMNVARMNFSHGSHEYHAETIRNCREAEKSYSA 441
               KM E     A M F         E      +AE S SA
Sbjct: 753 VPSAKMFE----AAEMTFVSQRINSEEELRLRLEQAEASLSA 790


>UniRef50_Q1DYT2 Cluster: Putative uncharacterized protein; n=1;
           Coccidioides immitis|Rep: Putative uncharacterized
           protein - Coccidioides immitis
          Length = 893

 Score = 33.1 bits (72), Expect = 5.0
 Identities = 19/46 (41%), Positives = 24/46 (52%), Gaps = 2/46 (4%)
 Frame = -1

Query: 318 SYITGCRSNSTDYSG--ETDVRRLGVNVETAHMLELGADVGDCGLF 187
           SYI G  ++  + SG  E DVRR G       + ELGAD   C +F
Sbjct: 229 SYIHGAETDEEEDSGFTEADVRRWGHEEVAERLRELGADPKHCEIF 274


>UniRef50_Q8D170 Cluster: UPF0255 protein YPO3224/y0964/YP_0709;
           n=41; Enterobacteriaceae|Rep: UPF0255 protein
           YPO3224/y0964/YP_0709 - Yersinia pestis
          Length = 415

 Score = 33.1 bits (72), Expect = 5.0
 Identities = 26/75 (34%), Positives = 34/75 (45%), Gaps = 2/75 (2%)
 Frame = +1

Query: 55  KGSSRSRKPPVSRNR--ELTDKYLHYNPLKMVYPTIHDGEIEAGAVEKPTVANVGSQLQH 228
           KG   S +  V  NR  E   KYL Y   ++ +P I DG   +G +  PTV +       
Sbjct: 141 KGDELSEQAEVLSNRAYEEAAKYLPYTLKELTFP-ISDGGSLSGFLHMPTVGSAPFPTVL 199

Query: 229 MCGLDIDSKSSYIRL 273
           MCG     +S Y RL
Sbjct: 200 MCGGLDTLQSDYHRL 214


>UniRef50_Q470K0 Cluster: RND efflux system, outer membrane
           lipoprotein, NodT; n=2; Cupriavidus|Rep: RND efflux
           system, outer membrane lipoprotein, NodT - Ralstonia
           eutropha (strain JMP134) (Alcaligenes eutrophus)
          Length = 503

 Score = 32.3 bits (70), Expect = 8.7
 Identities = 18/69 (26%), Positives = 30/69 (43%)
 Frame = +1

Query: 235 GLDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHGSHEYHAETIRNC 414
           GL+  S +S++        IGPA     +       G + AR  F   + +Y +  +R  
Sbjct: 345 GLESSSLASWLTAPSRFWAIGPALAGTLLDGGRRRAGEDSARAQFDASAADYRSTVLRAV 404

Query: 415 REAEKSYSA 441
           +E E  Y+A
Sbjct: 405 QEVEDGYAA 413


>UniRef50_A3QC46 Cluster: Sulfotransferase; n=1; Shewanella loihica
           PV-4|Rep: Sulfotransferase - Shewanella loihica (strain
           BAA-1088 / PV-4)
          Length = 531

 Score = 32.3 bits (70), Expect = 8.7
 Identities = 17/57 (29%), Positives = 29/57 (50%), Gaps = 1/57 (1%)
 Frame = +1

Query: 238 LDIDSKSSYIRLSGIICTIGPASRNVAVLEKMMETGMNVARMNFSHG-SHEYHAETI 405
           L ID   +     G+I T+ P ++ + V+    +  M V + +FSHG  + YH + I
Sbjct: 365 LVIDKNPNNFIHIGLIKTLFPEAKIINVIRDARDNAMGVYKQHFSHGHDYSYHLDDI 421


>UniRef50_Q940A6 Cluster: Putative uncharacterized protein
           At4g19440; n=2; Arabidopsis thaliana|Rep: Putative
           uncharacterized protein At4g19440 - Arabidopsis thaliana
           (Mouse-ear cress)
          Length = 825

 Score = 32.3 bits (70), Expect = 8.7
 Identities = 28/92 (30%), Positives = 44/92 (47%)
 Frame = +1

Query: 97  RELTDKYLHYNPLKMVYPTIHDGEIEAGAVEKPTVANVGSQLQHMCGLDIDSKSSYIRLS 276
           +E+T K   + P  +VY  + D  IEAG++ K         L    GL + S S+Y  L 
Sbjct: 354 KEMTKK--GFPPNVIVYNNLIDSFIEAGSLNKAIEIK---DLMVSKGLSLTS-STYNTLI 407

Query: 277 GIICTIGPASRNVAVLEKMMETGMNVARMNFS 372
              C  G A     +L++M+  G NV + +F+
Sbjct: 408 KGYCKNGQADNAERLLKEMLSIGFNVNQGSFT 439


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.315    0.131    0.373 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 573,702,475
Number of Sequences: 1657284
Number of extensions: 11296371
Number of successful extensions: 26914
Number of sequences better than 10.0: 153
Number of HSP's better than 10.0 without gapping: 26095
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 26827
length of database: 575,637,011
effective HSP length: 96
effective length of database: 416,537,747
effective search space used: 40820699206
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 42 (22.0 bits)

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