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Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= fner10d16r
         (746 letters)

Database: uniref50 
           1,657,284 sequences; 575,637,011 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:...   207   2e-52
UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole car...   153   3e-36
UniRef50_Q73PV9 Cluster: Phosphoribosylaminoimidazole carboxylas...   113   6e-24
UniRef50_O28997 Cluster: Phosphoribosylaminoimidazole carboxylas...   111   2e-23
UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila melanogaste...    79   1e-13
UniRef50_A5G876 Cluster: Phosphoribosylaminoimidazole carboxylas...    76   1e-12
UniRef50_Q83AA3 Cluster: Phosphoribosylaminoimidazole carboxylas...    74   3e-12
UniRef50_Q1MPV1 Cluster: Phosphoribosylcarboxyaminoimidazole (NC...    69   1e-10
UniRef50_O58058 Cluster: Phosphoribosylaminoimidazole carboxylas...    66   1e-09
UniRef50_Q2NEA3 Cluster: PurE; n=3; Archaea|Rep: PurE - Methanos...    65   2e-09
UniRef50_P41654 Cluster: Probable phosphoribosylaminoimidazole c...    64   3e-09
UniRef50_Q93J44 Cluster: Phosphoribosylaminoimidazole carboxylas...    64   5e-09
UniRef50_Q94IQ2 Cluster: Phosphoribosylaminoimidazole-succinocar...    62   1e-08
UniRef50_Q8A4S9 Cluster: Phosphoribosylaminoimidazole carboxylas...    61   3e-08
UniRef50_Q74AP6 Cluster: Phosphoribosylaminoimidazole carboxylas...    60   4e-08
UniRef50_A0LLY4 Cluster: Phosphoribosylaminoimidazole carboxylas...    59   1e-07
UniRef50_Q8PV25 Cluster: Phosphoribosylaminoimidazole carboxylas...    59   1e-07
UniRef50_Q7M7S1 Cluster: PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLAS...    59   1e-07
UniRef50_Q8XMK7 Cluster: Phosphoribosylaminoimidazole carboxylas...    58   2e-07
UniRef50_P22348 Cluster: Probable phosphoribosylaminoimidazole c...    58   2e-07
UniRef50_A1T5T8 Cluster: Phosphoribosylaminoimidazole carboxylas...    57   4e-07
UniRef50_Q4AJE5 Cluster: 1-(5-Phosphoribosyl)-5-amino-4-imidazol...    57   5e-07
UniRef50_A0JU62 Cluster: Phosphoribosylaminoimidazole carboxylas...    56   1e-06
UniRef50_Q11CU3 Cluster: Phosphoribosylaminoimidazole carboxylas...    54   3e-06
UniRef50_A2SPX9 Cluster: 1-(5-phosphoribosyl)-5-amino-4-imidazol...    54   5e-06
UniRef50_P96880 Cluster: Phosphoribosylaminoimidazole carboxylas...    54   5e-06
UniRef50_Q5XEE9 Cluster: Phosphoribosylaminoimidazole carboxylas...    52   2e-05
UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep: LO...    51   3e-05
UniRef50_P72157 Cluster: Phosphoribosylaminoimidazole carboxylas...    51   3e-05
UniRef50_Q2J4S5 Cluster: Phosphoribosylaminoimidazole carboxylas...    48   3e-04
UniRef50_A4M8A1 Cluster: 1-(5-phosphoribosyl)-5-amino-4-imidazol...    48   3e-04
UniRef50_P21264 Cluster: Phosphoribosylaminoimidazole carboxylas...    48   3e-04
UniRef50_Q55498 Cluster: Phosphoribosylaminoimidazole carboxylas...    48   3e-04
UniRef50_P15567 Cluster: Phosphoribosylaminoimidazole carboxylas...    46   7e-04
UniRef50_A7D0F6 Cluster: NCAIR mutase (PurE)-related protein; n=...    44   0.005
UniRef50_Q98FE6 Cluster: Phosphoribosylaminoimidazole carboxylas...    43   0.007
UniRef50_Q6BIQ2 Cluster: Similar to CA4826|IPF1206 Candida albic...    36   0.80 
UniRef50_A6CXW5 Cluster: Putative uncharacterized protein; n=1; ...    36   1.4  
UniRef50_A4G5F2 Cluster: Universal stress protein; n=4; Herminii...    35   1.8  
UniRef50_O28993 Cluster: Putative uncharacterized protein; n=1; ...    35   1.8  
UniRef50_A7H038 Cluster: Ncair mutase; n=8; Bacteria|Rep: Ncair ...    35   2.4  
UniRef50_Q8RJP6 Cluster: Putative uncharacterized protein; n=11;...    33   5.6  
UniRef50_Q2ADF8 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc...    33   5.6  
UniRef50_Q9YBE5 Cluster: PqqE homolog; n=4; Thermoprotei|Rep: Pq...    33   5.6  
UniRef50_Q8AAD6 Cluster: Indole-3-glycerol phosphate synthase; n...    33   5.6  
UniRef50_P73194 Cluster: Slr1699 protein; n=1; Synechocystis sp....    33   7.5  
UniRef50_A0RWQ1 Cluster: Phosphoribosylcarboxyaminoimidazole (NC...    33   7.5  
UniRef50_Q89GN0 Cluster: Blr6315 protein; n=1; Bradyrhizobium ja...    33   9.9  
UniRef50_Q87WE4 Cluster: Putative uncharacterized protein; n=1; ...    33   9.9  
UniRef50_A4IPG9 Cluster: NCAIR mutase (Pure)-related protein; n=...    33   9.9  
UniRef50_Q9VIK2 Cluster: CG9317-PA, isoform A; n=7; Endopterygot...    33   9.9  
UniRef50_A7DMC3 Cluster: Phosphoribosylaminoimidazole carboxylas...    33   9.9  

>UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:
           Phosphoribosylaminoimidazole- succinocarboxamide
           synthase (EC 6.3.2.6) (SAICAR synthetase);
           Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
           (AIR carboxylase) (AIRC)]; n=60; Eumetazoa|Rep:
           Multifunctional protein ADE2 [Includes:
           Phosphoribosylaminoimidazole- succinocarboxamide
           synthase (EC 6.3.2.6) (SAICAR synthetase);
           Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
           (AIR carboxylase) (AIRC)] - Homo sapiens (Human)
          Length = 425

 Score =  207 bits (506), Expect = 2e-52
 Identities = 105/195 (53%), Positives = 134/195 (68%), Gaps = 2/195 (1%)
 Frame = -2

Query: 745 DKQVYRXXXXXXXXXXXXVKRNFAWVKDQLDFL-KPTIHHKVVVFMGSPADQEHCQKIAK 569
           DKQ YR            VK+NF WV ++++ L K     +VVV MGS +D  HC+KI K
Sbjct: 227 DKQSYRDLKEVTPEGLQMVKKNFEWVAERVELLLKSESQCRVVVLMGSTSDLGHCEKIKK 286

Query: 568 AARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYP 389
           A    G+  +LRVTSAHK  +ETLRI  +YE      VF+AVAGRSNGLGPV+SGNT+YP
Sbjct: 287 ACGNFGIPCELRVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYP 346

Query: 388 VINCPP-PSDKLVQDIWSSLSVPSGLGCATVIYPDSAALMAAQIIGLQDYLVWGRLRSKQ 212
           VI+CPP   D  VQD+WSSL +PSGLGC+TV+ P+ +A  AAQI GL ++LVW +LR+  
Sbjct: 347 VISCPPLTPDWGVQDVWSSLRLPSGLGCSTVLSPEGSAQFAAQIFGLSNHLVWSKLRASI 406

Query: 211 LDMAHSLRQADKKLR 167
           L+   SL+QADKK+R
Sbjct: 407 LNTWISLKQADKKIR 421


>UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole
           carboxylase, phosphoribosylaminoimidazole
           succinocarboxamide synthetase; n=2; Coelomata|Rep:
           phosphoribosylaminoimidazole carboxylase,
           phosphoribosylaminoimidazole succinocarboxamide
           synthetase - Bos Taurus
          Length = 402

 Score =  153 bits (372), Expect = 3e-36
 Identities = 76/127 (59%), Positives = 95/127 (74%), Gaps = 4/127 (3%)
 Frame = -2

Query: 535 RVTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPP-PSDK 359
           RVTSAHK  +ETLRI  +YE      VF+AVAGRSNGLGPVLSGNT+YPVI+CPP   D 
Sbjct: 273 RVTSAHKGPDETLRIKAEYEGDGIPTVFVAVAGRSNGLGPVLSGNTAYPVISCPPLTPDW 332

Query: 358 LVQDIWSSLSVPS---GLGCATVIYPDSAALMAAQIIGLQDYLVWGRLRSKQLDMAHSLR 188
             QD+WSSL +PS   GLGC+T++ P+ +A  AAQI GL ++L+W RLR+  L+   SL+
Sbjct: 333 GAQDVWSSLRLPSEPIGLGCSTILSPEGSAQFAAQIFGLNNHLIWARLRASVLNTWISLK 392

Query: 187 QADKKLR 167
           QADKK+R
Sbjct: 393 QADKKIR 399


>UniRef50_Q73PV9 Cluster: Phosphoribosylaminoimidazole carboxylase,
           PurE protein; n=1; Treponema denticola|Rep:
           Phosphoribosylaminoimidazole carboxylase, PurE protein -
           Treponema denticola
          Length = 159

 Score =  113 bits (271), Expect = 6e-24
 Identities = 57/154 (37%), Positives = 88/154 (57%), Gaps = 1/154 (0%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V++ MGS +D  H +KIA   +  G++  +R+ SAHK  E  + ++++YE      ++I 
Sbjct: 5   VIILMGSSSDMGHAEKIASELKTFGIEYAIRIGSAHKTAEHVVSMLKEYEALDRPKLYIT 64

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLV-QDIWSSLSVPSGLGCATVIYPDSAALMA 269
           +AGRSN L   + G      I CPPPSD     DI+SSL +PSG+  A V+ P +AAL+A
Sbjct: 65  IAGRSNALSGFVDGFVKGATIACPPPSDSFAGADIYSSLRMPSGISPALVLEPKNAALLA 124

Query: 268 AQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLR 167
           A+I  L D  +   ++S     A  + + D KL+
Sbjct: 125 ARIFSLYDKEIADSVKSYMESNAQKIIEDDSKLK 158


>UniRef50_O28997 Cluster: Phosphoribosylaminoimidazole carboxylase
           catalytic subunit; n=1; Archaeoglobus fulgidus|Rep:
           Phosphoribosylaminoimidazole carboxylase catalytic
           subunit - Archaeoglobus fulgidus
          Length = 180

 Score =  111 bits (267), Expect = 2e-23
 Identities = 62/155 (40%), Positives = 94/155 (60%), Gaps = 1/155 (0%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           K V+ MGS +D ++ +KIA    + G+D  +R+ SAHK  E+ L I+++YE     +VF+
Sbjct: 28  KAVIIMGSKSDLDYSKKIASKLADFGIDAVMRIASAHKTPEKVLEIIKEYEKED--VVFV 85

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL-VQDIWSSLSVPSGLGCATVIYPDSAALM 272
            VAGRSN L   +  NTS PVI  PP SDK    DI+SS+ +PSG+    V+  ++AAL 
Sbjct: 86  TVAGRSNALSGFVDANTSKPVIASPPYSDKFGGADIFSSIRMPSGVAPMLVLEAENAALA 145

Query: 271 AAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLR 167
            A+I  L+D  V  ++   Q +    + +AD++LR
Sbjct: 146 VAKIFALKDEGVREKVVQFQENKRREIYKADEELR 180


>UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila
           melanogaster|Rep: CG17024-PA - Drosophila melanogaster
           (Fruit fly)
          Length = 395

 Score = 79.0 bits (186), Expect = 1e-13
 Identities = 42/115 (36%), Positives = 68/115 (59%), Gaps = 1/115 (0%)
 Frame = -2

Query: 508 EETLRIMQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPP-PSDKLVQDIWSSL 332
           EE L+I++ +E     LVF+ V  R N L  V+S NTS+PVINC P  SD +  ++WS+ 
Sbjct: 280 EEALQILRTFEAVINNLVFVTVDERLNSLANVISANTSFPVINCTPIQSDTMFMNMWSNS 339

Query: 331 SVPSGLGCATVIYPDSAALMAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLR 167
           +  S         P++AA   A ++ L ++++W +LR  QL+   ++++ D KLR
Sbjct: 340 NPTSD--------PEAAAKHVASLLSLGNFMIWSKLRVNQLNKQIAIKKIDTKLR 386


>UniRef50_A5G876 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=5; Bacteria|Rep:
           Phosphoribosylaminoimidazole carboxylase, catalytic
           subunit - Geobacter uraniumreducens Rf4
          Length = 168

 Score = 75.8 bits (178), Expect = 1e-12
 Identities = 49/159 (30%), Positives = 85/159 (53%), Gaps = 6/159 (3%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           +V++ MGS +D     + AK   E  +  ++R++SAH++   T  +  + ED  G  V I
Sbjct: 5   QVLIVMGSDSDLPVMGEAAKVLTEFDVPFEMRISSAHRSPRRTGLLASEAED-RGVKVVI 63

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIY----PD 287
           A AG +  L  V++  T+ PVI  P     L  V  ++S++ +P G+  AT+        
Sbjct: 64  AGAGMAAHLAGVVAAETTLPVIGVPIGGGALNGVDALYSTVQMPGGIPVATMAIGRAGAK 123

Query: 286 SAALMAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKL 170
           +AA++A QI+ L D  +  +L+S +  MA  + + DK+L
Sbjct: 124 NAAILAVQILALADVSLAAKLKSYRAQMAQEVDEKDKQL 162


>UniRef50_Q83AA3 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=9; Proteobacteria|Rep:
           Phosphoribosylaminoimidazole carboxylase, catalytic
           subunit - Coxiella burnetii
          Length = 166

 Score = 74.1 bits (174), Expect = 3e-12
 Identities = 47/161 (29%), Positives = 82/161 (50%), Gaps = 6/161 (3%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D    +      + LG+  +  + SAH+  +ET+  ++   D  G  VFIA
Sbjct: 6   VAILMGSDSDLSTMETAFTELKSLGIPFEAHILSAHRTPKETVEFVEN-ADNRGCAVFIA 64

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGL--GCATV--IYPDS 284
            AG +  L   ++ +T  PVI  P     L  +  + S++ +P G+   C  +      +
Sbjct: 65  AAGLAAHLAGTIAAHTLKPVIGVPMAGGSLGGLDALLSTVQMPGGVPVACTAIGKAGAKN 124

Query: 283 AALMAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLRNQ 161
           AA++AAQII LQD  +  +L  ++     +L++AD+ L+ Q
Sbjct: 125 AAILAAQIIALQDKSIAQKLVQQRTAKRETLKKADENLQTQ 165


>UniRef50_Q1MPV1 Cluster: Phosphoribosylcarboxyaminoimidazole
           (NCAIR) mutase; n=1; Lawsonia intracellularis
           PHE/MN1-00|Rep: Phosphoribosylcarboxyaminoimidazole
           (NCAIR) mutase - Lawsonia intracellularis (strain
           PHE/MN1-00)
          Length = 171

 Score = 68.9 bits (161), Expect = 1e-10
 Identities = 49/151 (32%), Positives = 74/151 (49%), Gaps = 6/151 (3%)
 Frame = -2

Query: 634 HHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALV 455
           H KV +F+GSP+D+       +   +L +     V+SAH+  E T  ++   E  +G  V
Sbjct: 3   HVKVAIFIGSPSDESIVSPCTEILTQLNIPYIFTVSSAHRTPERTAELIDSLE-ANGCEV 61

Query: 454 FIAVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD-- 287
           FI  AG +  L   ++  T  PVI  P  S  L  +  + +++ +PSG   ATV      
Sbjct: 62  FICAAGMAAHLAGAVAARTLKPVIGIPITSSSLGGMDALLATVQMPSGYPVATVALDTAG 121

Query: 286 --SAALMAAQIIGLQDYLVWGRLRSKQLDMA 200
             +AA +AAQI+ L D  +      KQLD A
Sbjct: 122 ARNAAWLAAQILALHDSKI-----KKQLDAA 147


>UniRef50_O58058 Cluster: Phosphoribosylaminoimidazole carboxylase
           catalytic subunit; n=94; cellular organisms|Rep:
           Phosphoribosylaminoimidazole carboxylase catalytic
           subunit - Pyrococcus horikoshii
          Length = 177

 Score = 65.7 bits (153), Expect = 1e-09
 Identities = 46/156 (29%), Positives = 80/156 (51%), Gaps = 4/156 (2%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D    ++ A+   E G+  ++ + SAH+  E      ++ E+  G  V IA
Sbjct: 12  VGIIMGSDSDLPVMKEAARILEEFGVPYEITIISAHRTPERAYEYAKKAEE-RGIEVIIA 70

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD--SAA 278
            AG +  L  +++  T  PVI  P  S  L  +  + S + +PSG+  ATV   +  +AA
Sbjct: 71  GAGGAAHLPGIIASLTVLPVIGVPIKSKALNGLDSLLSIVQMPSGIPVATVAIDNAKNAA 130

Query: 277 LMAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKL 170
           L+A +I+G++   +  +LR    DM   + +  K+L
Sbjct: 131 LLALRILGIKYPEIKEKLRRYMKDMKRKVEEKAKRL 166


>UniRef50_Q2NEA3 Cluster: PurE; n=3; Archaea|Rep: PurE -
           Methanosphaera stadtmanae (strain DSM 3091)
          Length = 354

 Score = 64.9 bits (151), Expect = 2e-09
 Identities = 50/162 (30%), Positives = 80/162 (49%), Gaps = 4/162 (2%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           KV++ +GS +D +  +K  K   ++ +  DLRV SAH+       IM  Y D  G  VFI
Sbjct: 19  KVMIILGSGSDYKIAEKTVKVFEQMKVPYDLRVASAHRTHNRIKDIMTNYVD--GIEVFI 76

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCAT--VIYPDSA 281
            +AG S  L  V++  T+ PVI   P + K+  +  + S   +  G   AT  +   ++A
Sbjct: 77  GIAGLSAHLPGVIASYTTKPVI-AVPVNGKIEGLDALLSCTEMQLGTPVATMGIDRGENA 135

Query: 280 ALMAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLRNQTA 155
           A +A QII   D  +   L  K+    H +  ++K+L  + A
Sbjct: 136 AWLACQIIACNDEKMREALVDKRNSYNHKMETSEKELIEKIA 177


>UniRef50_P41654 Cluster: Probable phosphoribosylaminoimidazole
           carboxylase; n=2; Methanothermobacter thermautotrophicus
           str. Delta H|Rep: Probable phosphoribosylaminoimidazole
           carboxylase - Methanobacterium thermoautotrophicum
          Length = 334

 Score = 64.1 bits (149), Expect = 3e-09
 Identities = 44/131 (33%), Positives = 67/131 (51%), Gaps = 3/131 (2%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           +V++ +GS +D    +K  +   EL +  DLRV SAH+  E+   I+ +     G  VFI
Sbjct: 4   RVMILLGSASDFRIAEKAMEIFEELRIPYDLRVASAHRTHEKVKAIVSEAVKA-GVEVFI 62

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQD---IWSSLSVPSGLGCATVIYPDSAA 278
            +AG S  L  ++S NT  PVI  P        D     S +  P+ +    V   ++AA
Sbjct: 63  GIAGLSAHLPGMISANTHRPVIGVPVDVKLGGLDALFACSQMPFPAPVATVGVDRGENAA 122

Query: 277 LMAAQIIGLQD 245
           ++AAQIIG+ D
Sbjct: 123 ILAAQIIGIGD 133



 Score = 48.4 bits (110), Expect = 2e-04
 Identities = 37/138 (26%), Positives = 69/138 (50%), Gaps = 3/138 (2%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V V  GS +D +  +K       +G+  DL V S  +  E   R +++ E+     +FIA
Sbjct: 191 VSVIPGSYSDMKIAKKTTMFLERMGISYDLNVISPIRYPERFERYLEKMENVK---LFIA 247

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQD-IWSSLSVPSGLGCATVIYPD--SAAL 275
           ++G S  +   +   +  PVI  P P      D + S +++P G+   TV   +  +AA+
Sbjct: 248 ISGLSAHVTGAVVALSDRPVIGVPCPLKMNGWDSLLSMINMPPGVPVGTVGVGNGGNAAI 307

Query: 274 MAAQIIGLQDYLVWGRLR 221
           +AA+++G+ D  +  R++
Sbjct: 308 LAAEMLGIYDEKIESRIK 325


>UniRef50_Q93J44 Cluster: Phosphoribosylaminoimidazole carboxylase
           catalytic subunit PurE; n=47; cellular organisms|Rep:
           Phosphoribosylaminoimidazole carboxylase catalytic
           subunit PurE - Streptomyces coelicolor
          Length = 180

 Score = 63.7 bits (148), Expect = 5e-09
 Identities = 49/159 (30%), Positives = 77/159 (48%), Gaps = 4/159 (2%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D    +  AKA  E  +  ++ V SAH+   E +   +Q     G    IA
Sbjct: 11  VGIVMGSDSDWPVMEAAAKALDEFEVPYEVDVVSAHRMPHEMIAYGEQAAG-RGLKAIIA 69

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIY--PDSAA 278
            AG +  L  +L+  T  PVI  P P   L  +  + S + +P+G+  ATV      +A 
Sbjct: 70  GAGGAAHLPGMLASVTPLPVIGVPVPLKYLDGMDSLLSIVQMPAGVPVATVSVGGARNAG 129

Query: 277 LMAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLRNQ 161
           L+AA+I+   D  + GR+R  Q D+     +  K+LR +
Sbjct: 130 LLAARILAAHDEELLGRMREFQQDLNDQATEKGKRLRTK 168


>UniRef50_Q94IQ2 Cluster:
           Phosphoribosylaminoimidazole-succinocarboxamide
           synthase; n=1; Crypthecodinium cohnii|Rep:
           Phosphoribosylaminoimidazole-succinocarboxamide synthase
           - Crypthecodinium cohnii (Dinoflagellate)
          Length = 522

 Score = 62.1 bits (144), Expect = 1e-08
 Identities = 37/152 (24%), Positives = 68/152 (44%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V++  GS +D  H + + K   +  +   +R+ SAHK      +++Q Y  +   ++ + 
Sbjct: 356 VIIAAGSDSDMPHLETLKKELAKFKIPSQIRICSAHKQPGRLEQLIQAYNKSVEPIMLVG 415

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQDIWSSLSVPSGLGCATVIYPDSAALMAA 266
            AG ++ L    S + ++PV++CPP          + L+ P G   A ++ P +    AA
Sbjct: 416 CAGGTDALSGTASYSATFPVVSCPPDGMNS-----TCLTNPPGSSNAFIVKPANVGKFAA 470

Query: 265 QIIGLQDYLVWGRLRSKQLDMAHSLRQADKKL 170
           Q        V   L +   +    L QAD+ L
Sbjct: 471 QFFASHCPKVAAELEANIQEKIRKLEQADESL 502


>UniRef50_Q8A4S9 Cluster: Phosphoribosylaminoimidazole carboxylase;
           n=4; Bacteroides|Rep: Phosphoribosylaminoimidazole
           carboxylase - Bacteroides thetaiotaomicron
          Length = 171

 Score = 60.9 bits (141), Expect = 3e-08
 Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D    +K A+   ++ +  ++   SAH+ T E +    +   + G  V IA
Sbjct: 7   VSIIMGSTSDLPVMEKAAQLLNDMHVPFEMNALSAHR-TPEAVEEFAKNARSRGIKVIIA 65

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD--SAA 278
            AG +  L  V++ NT+ PVI  P     L  V  ++S + +P G+  ATV      +AA
Sbjct: 66  AAGMAAALPGVIAANTTLPVIGVPVKGSVLDGVDALYSIIQMPPGIPVATVAINGAMNAA 125

Query: 277 LMAAQIIGLQD 245
           ++A Q++ L D
Sbjct: 126 ILAIQMLALSD 136


>UniRef50_Q74AP6 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=1; Geobacter sulfurreducens|Rep:
           Phosphoribosylaminoimidazole carboxylase, catalytic
           subunit - Geobacter sulfurreducens
          Length = 183

 Score = 60.5 bits (140), Expect = 4e-08
 Identities = 41/130 (31%), Positives = 67/130 (51%), Gaps = 4/130 (3%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V +  GSP D     K+     ELG+  ++ V SAH+  ++ L  + +     G  V I 
Sbjct: 20  VGILTGSPNDLPTVVKVRDTLTELGIPSEIVVASAHRTPDKVLAYLDR-AHKEGVQVLIG 78

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPDS--AA 278
            AG +  L  V++G+T  PVI  P  +  L  +  + S++ +P G+  ATV    S  AA
Sbjct: 79  CAGVAAHLAGVIAGHTRLPVIGLPLGNGPLSGMDSLLSTVQMPPGVPVATVAIDGSRNAA 138

Query: 277 LMAAQIIGLQ 248
           ++AA+I+ L+
Sbjct: 139 MLAARILALK 148


>UniRef50_A0LLY4 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=1; Syntrophobacter fumaroxidans
           MPOB|Rep: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit - Syntrophobacter fumaroxidans (strain
           DSM 10017 / MPOB)
          Length = 180

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 42/152 (27%), Positives = 76/152 (50%), Gaps = 6/152 (3%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           +V + MGS +D    +   +   +  +  ++R+ SAH++ +ET R         G  V I
Sbjct: 9   RVGILMGSESDLSVMESAFRILDDFEVPYEVRILSAHRSPDETARYADS-AGQRGVQVLI 67

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD---- 287
           A AG +  L  V++  T+ PVI  P  S  L  +  + +++ +P G+  AT+        
Sbjct: 68  AGAGWAAHLAGVVASRTTLPVIGVPIDSSPLQGMDALLATVQMPPGIPVATMCIGRGGAL 127

Query: 286 SAALMAAQIIGLQDYLVWGRLRSKQLDMAHSL 191
           +AAL A QI+ L D  + G+L++ ++ M   +
Sbjct: 128 NAALFALQILALNDRTLDGKLKAYRVRMTEEV 159


>UniRef50_Q8PV25 Cluster: Phosphoribosylaminoimidazole carboxylase;
           n=5; cellular organisms|Rep:
           Phosphoribosylaminoimidazole carboxylase -
           Methanosarcina mazei (Methanosarcina frisia)
          Length = 169

 Score = 59.3 bits (137), Expect = 1e-07
 Identities = 39/158 (24%), Positives = 80/158 (50%), Gaps = 3/158 (1%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           VV+ +GS +D+E  +K  +     G++  + V SAH+       I++    T     FIA
Sbjct: 4   VVIILGSKSDKEVARKATEVFDRFGIEYTITVASAHRTPARLAEIIETAHKT-DVKAFIA 62

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSD-KLVQDIWSSLSVPSGL--GCATVIYPDSAAL 275
           +AG S  L  V++ +T  PVI  P  S    +  + S   +P+G+   C  +   D+AA+
Sbjct: 63  IAGLSAHLPGVVASSTIKPVIGVPVNSALDGIDALLSIAQMPTGIPVACVGIGRGDNAAI 122

Query: 274 MAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLRNQ 161
           +A Q++ +++  +  +L + + ++   + +  + L ++
Sbjct: 123 LAVQLLAVENGELAEKLSNYRKELVEMIEKDAESLMDE 160


>UniRef50_Q7M7S1 Cluster: PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE
           CATALYTIC SUBUNIT; n=19; delta/epsilon subdivisions|Rep:
           PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC
           SUBUNIT - Wolinella succinogenes
          Length = 164

 Score = 58.8 bits (136), Expect = 1e-07
 Identities = 42/151 (27%), Positives = 79/151 (52%), Gaps = 6/151 (3%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D E  ++ A+  ++  +  ++ ++SAH++   T   + + E   GA VFIA
Sbjct: 4   VSILMGSKSDAEVMRECAEIFKKFDVPYEMIISSAHRSPVRTKEYVLEAE-ARGAKVFIA 62

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPDSAAL- 275
            AG +  L   +S  T+ PVI  P     L  +  + S++ +PSG+   TV    + A+ 
Sbjct: 63  AAGMAAHLAGAISSMTTKPVIGVPMGGGTLGGLDALLSTVQMPSGMPVGTVAIGKTGAVN 122

Query: 274 ---MAAQIIGLQDYLVWGRLRSKQLDMAHSL 191
              +A QI+ L +  + G+L+  ++  A ++
Sbjct: 123 SAYLAMQILALGNDELAGKLKEDRVMKAKNV 153


>UniRef50_Q8XMK7 Cluster: Phosphoribosylaminoimidazole carboxylase
           catalytic subunit; n=11; Clostridium|Rep:
           Phosphoribosylaminoimidazole carboxylase catalytic
           subunit - Clostridium perfringens
          Length = 159

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 42/147 (28%), Positives = 75/147 (51%), Gaps = 3/147 (2%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           KV +F GS +D +  +    A +E G+  +  + SAH+  E+ +  +++ E   G  V I
Sbjct: 2   KVAIFFGSKSDIDVMKGAGNALKEFGIPYNAYILSAHRVPEKLIETLEKIE-KEGCEVII 60

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQD-IWSSLSVPSGLGCATVIYPDS--AA 278
           A AG +  L  V++ +T  PVI  P  +     D + S + +P  +  ATV   +S  A 
Sbjct: 61  AGAGLAAHLPGVIASHTILPVIGVPVRAAVEGMDALLSIVQMPKSIPVATVGINNSYNAG 120

Query: 277 LMAAQIIGLQDYLVWGRLRSKQLDMAH 197
           ++A Q++ L+   +  +L   ++DM H
Sbjct: 121 MLAVQMLSLKYPELREKLIQFRIDMKH 147


>UniRef50_P22348 Cluster: Probable phosphoribosylaminoimidazole
           carboxylase; n=9; Euryarchaeota|Rep: Probable
           phosphoribosylaminoimidazole carboxylase -
           Methanobrevibacter smithii
          Length = 339

 Score = 58.0 bits (134), Expect = 2e-07
 Identities = 54/199 (27%), Positives = 89/199 (44%), Gaps = 4/199 (2%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           KV++ +GS +D    +K  K   +L +   L++ SAH+ T + +R +       G  VFI
Sbjct: 4   KVMIILGSGSDIAIAEKSMKILEKLEIPYSLKIASAHR-TPDLVRELVVQGTNAGIKVFI 62

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQD-IWSSLSVPSGLGCATVIYP--DSAA 278
            +AG +  L   ++  T  PVI  P        D ++SS+ +P     ATV     D+ A
Sbjct: 63  GIAGLAAHLPGAIAAYTHKPVIGVPVDVKVSGLDALYSSVQMPYPSPVATVGIDRGDNGA 122

Query: 277 LMAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLRNQTA*CITKYKMKNN-MQVPRLV 101
           ++AA+I+GL D      +R K L+     RQ   K   +    I    + N+ +++  L 
Sbjct: 123 ILAARILGLYD----EEIRKKVLESKEGYRQKVIKNNEEIVQKIDNPHITNDFLRIKNLE 178

Query: 100 GRTINNRKNNHIFTKNNEM 44
                   N     KN E+
Sbjct: 179 LNETTEEFNGSYINKNAEV 197



 Score = 34.7 bits (76), Expect = 2.4
 Identities = 30/131 (22%), Positives = 66/131 (50%), Gaps = 3/131 (2%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDT-HGALVF 452
           +VV+ +G   D    +K++     L +  D++V    ++ ++     + Y +T   A +F
Sbjct: 196 EVVIIVGRHTDLITGKKVSVTLDRLKIPHDMQVICPIRSGKK----FRAYVNTMKNAKIF 251

Query: 451 IAVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQDIWSSLSVPSGLGCATVIYPD--SAA 278
           I +   S+ +   L G T  PVI  P  ++     + S++++P G+  ATV   +  +AA
Sbjct: 252 IGINSNSSQVSGGLVGLTEKPVIGVPCENELGNNYLLSTVNMPPGVPVATVGVNNGRNAA 311

Query: 277 LMAAQIIGLQD 245
           +++ +I+ + +
Sbjct: 312 VLSGEILSINN 322


>UniRef50_A1T5T8 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=7; cellular organisms|Rep:
           Phosphoribosylaminoimidazole carboxylase, catalytic
           subunit - Mycobacterium vanbaalenii (strain DSM 7251 /
           PYR-1)
          Length = 166

 Score = 57.2 bits (132), Expect = 4e-07
 Identities = 45/160 (28%), Positives = 76/160 (47%), Gaps = 4/160 (2%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           +V + MGS +D     + A+A  E  +  ++ V SAH+     L          G  V I
Sbjct: 4   RVGLIMGSDSDWPVMSEAAEALAEFDVPFEVGVVSAHRTPARMLSYAADAAG-RGLEVII 62

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIY--PDSA 281
           A AG +  L  +++  T  PVI  P P  +L  +  + S + +P+G+  ATV      +A
Sbjct: 63  AGAGGAAHLPGMVASATPLPVIGVPVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNA 122

Query: 280 ALMAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLRNQ 161
            L+A +I+G  D  +  R+ + Q  +   + Q D+ LR +
Sbjct: 123 GLLAVRILGAADGALRDRMAAYQASLEQMVLQKDEALRQK 162


>UniRef50_Q4AJE5 Cluster:
           1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate
           (AIR) carboxylase; n=2; Bacteria|Rep:
           1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate
           (AIR) carboxylase - Chlorobium phaeobacteroides BS1
          Length = 174

 Score = 56.8 bits (131), Expect = 5e-07
 Identities = 46/159 (28%), Positives = 79/159 (49%), Gaps = 4/159 (2%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D +  ++ A    E  +  ++ V SAH+ T + L        ++G  + IA
Sbjct: 12  VGILMGSDSDFDIMKEAAAVLDEFSIPYEMSVISAHR-TPKDLEAYATQAKSNGLKIIIA 70

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLV-QD-IWSSLSVPSGLGCATVIYPD--SAA 278
            AG +  L  V +  T  PVI  P  + KL  QD ++S + +P G+  ATV   +  + A
Sbjct: 71  GAGAAAHLPGVTAAFTVLPVIGVPIFNKKLSGQDSLYSIVQMPPGIPVATVGIDNARNGA 130

Query: 277 LMAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLRNQ 161
           LMA  I+ L D  +   L   +  +A + R  ++K++ +
Sbjct: 131 LMAVHILALTDPSIMSSLEEFREKLAEASRLKNRKVQEK 169


>UniRef50_A0JU62 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=4; cellular organisms|Rep:
           Phosphoribosylaminoimidazole carboxylase, catalytic
           subunit - Arthrobacter sp. (strain FB24)
          Length = 196

 Score = 55.6 bits (128), Expect = 1e-06
 Identities = 48/151 (31%), Positives = 73/151 (48%), Gaps = 6/151 (3%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D    +  A+A  E G+  +  V SAH+   E +R  Q   +  G  V IA
Sbjct: 19  VGLVMGSDSDWPVMEAAAEALAEFGIPFEADVVSAHRMPTEMIRYGQTAHE-RGLRVIIA 77

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD--SAA 278
            AG +  L  +L+  T  PVI  P P   L  +  + S + +P+G+  ATV      +A 
Sbjct: 78  GAGGAAHLPGMLASVTPLPVIGVPVPLKTLDGMDSLLSIVQMPAGVPVATVSIAGARNAG 137

Query: 277 LMAAQII--GLQDYLVWGRLRSKQLDMAHSL 191
           L+A +++  G  D  V  RLR   ++ A  L
Sbjct: 138 LLAVRMLASGTDDLAV--RLRDDLIEFAQEL 166


>UniRef50_Q11CU3 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=19; Bacteria|Rep:
           Phosphoribosylaminoimidazole carboxylase, catalytic
           subunit - Mesorhizobium sp. (strain BNC1)
          Length = 165

 Score = 54.4 bits (125), Expect = 3e-06
 Identities = 45/140 (32%), Positives = 67/140 (47%), Gaps = 6/140 (4%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D E  +  A     L +  D+R+ SAH+ T + L    +     G  V IA
Sbjct: 8   VAIIMGSQSDWETMRHAADILETLEISHDVRIVSAHR-TPDRLYAFAKGAKAEGIRVIIA 66

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLV-QD-IWSSLSVPSGLGCATVIYPDS---- 284
            AG +  L  + +  TS PV   P  S  L  QD + S + +P+G+   T+    S    
Sbjct: 67  GAGGAAHLPGMTAALTSLPVFGVPVQSKALSGQDSLLSIVQMPAGIPVGTLAIGRSGAVN 126

Query: 283 AALMAAQIIGLQDYLVWGRL 224
           AAL+AA ++ L D  +  RL
Sbjct: 127 AALLAAAVLALSDEALAARL 146


>UniRef50_A2SPX9 Cluster:
           1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate
           (AIR) carboxylase; n=1; Methanocorpusculum labreanum
           Z|Rep:
           1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate
           (AIR) carboxylase - Methanocorpusculum labreanum (strain
           ATCC 43576 / DSM 4855 / Z)
          Length = 129

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 5/130 (3%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           +V V  GS +DQ    K     +   +  D++  SAH+  ++    + +Y  +  AL+FI
Sbjct: 3   EVAVIAGSVSDQAIVDKATAVLQSYNISFDVQFISAHRDADK----LDEYVKSSDALIFI 58

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQDIWSSLSV---PSG--LGCATVIYPDS 284
            +AG S  L  V++  T  PVI   P S K+   + + LS+   P G  + C  V   ++
Sbjct: 59  CIAGMSAALPGVVAARTKKPVIGV-PVSGKIAGGLDALLSIAQMPKGVPVACMAVDGGEN 117

Query: 283 AALMAAQIIG 254
           A   AA+I+G
Sbjct: 118 AGHFAARILG 127


>UniRef50_P96880 Cluster: Phosphoribosylaminoimidazole carboxylase
           catalytic subunit; n=58; cellular organisms|Rep:
           Phosphoribosylaminoimidazole carboxylase catalytic
           subunit - Mycobacterium tuberculosis
          Length = 174

 Score = 53.6 bits (123), Expect = 5e-06
 Identities = 45/158 (28%), Positives = 77/158 (48%), Gaps = 4/158 (2%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           +V V MGS +D       A A  E  +  ++RV SAH+ T E +    +     G  V I
Sbjct: 9   RVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVSAHR-TPEAMFSYARGAAERGLEVII 67

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIY--PDSA 281
           A AG +  L  +++  T  PVI  P P  +L  +  + S + +P+G+  ATV      +A
Sbjct: 68  AGAGGAAHLPGMVAAATPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAGNA 127

Query: 280 ALMAAQIIGLQDYLVWGRLRSKQLDMAHSLRQADKKLR 167
            L+A +++G  +  +  R+ + Q  +A  +   D +L+
Sbjct: 128 GLLAVRMLGAANPQLRARIVAFQDRLADVVAAKDAELQ 165


>UniRef50_Q5XEE9 Cluster: Phosphoribosylaminoimidazole carboxylase
           carboxyltransferase subunit; n=18; Streptococcus|Rep:
           Phosphoribosylaminoimidazole carboxylase
           carboxyltransferase subunit - Streptococcus pyogenes
           serotype M6
          Length = 203

 Score = 52.0 bits (119), Expect = 2e-05
 Identities = 36/133 (27%), Positives = 67/133 (50%), Gaps = 6/133 (4%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           + + MGS +D    QK A+     G+  + +V SAH+  +   +  ++     G  + IA
Sbjct: 46  ISIIMGSKSDWATMQKTAEILDNFGIAYEKKVVSAHRTPDLMFKHAEEARG-RGIKIIIA 104

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD----S 284
            AG +  L  +++  T+ PVI  P  S  L  +  ++S + +P G+  AT+   +    +
Sbjct: 105 GAGGAAHLPGMVAAKTTLPVIGVPVKSRVLSGLDSLYSIVQMPGGVPVATMAIGEAGATN 164

Query: 283 AALMAAQIIGLQD 245
           AAL A +I+ ++D
Sbjct: 165 AALTALRILSIED 177


>UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep:
           LOC431975 protein - Xenopus laevis (African clawed frog)
          Length = 371

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 22/51 (43%), Positives = 34/51 (66%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYE 476
           +VV+ M S +D  HC++I K+  + G+  +LRV SAH   +ETL I+ +YE
Sbjct: 305 RVVLLMESTSDLAHCEEIKKSCTKYGMKCELRVASAHTGPQETLDILAEYE 355


>UniRef50_P72157 Cluster: Phosphoribosylaminoimidazole carboxylase
           catalytic subunit; n=126; Bacteria|Rep:
           Phosphoribosylaminoimidazole carboxylase catalytic
           subunit - Pseudomonas aeruginosa
          Length = 163

 Score = 51.2 bits (117), Expect = 3e-05
 Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 6/130 (4%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V V MGS +D       A    +LG+  +++V SAH+  +   +  ++ E   G  V IA
Sbjct: 5   VGVIMGSKSDWSTLSHTADMLDKLGIPYEVKVVSAHRTPDLLFQYAEEAEG-RGLEVIIA 63

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD----S 284
            AG +  L  + +  T  PV+  P  S  L  V  + S + +P+G+  AT+        +
Sbjct: 64  GAGGAAHLPGMCAAKTHLPVLGVPVQSSMLSGVDSLLSIVQMPAGVPVATLAIGKAGAVN 123

Query: 283 AALMAAQIIG 254
           AAL++A I+G
Sbjct: 124 AALLSASILG 133


>UniRef50_Q2J4S5 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=3; Frankia|Rep:
           Phosphoribosylaminoimidazole carboxylase, catalytic
           subunit - Frankia sp. (strain CcI3)
          Length = 174

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 4/134 (2%)
 Frame = -2

Query: 634 HHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALV 455
           H +V +  GSP+D +   K        G+  +    SAH+A       + Q        V
Sbjct: 10  HPQVAIVFGSPSDTQTMSKAGATLERFGVPYEQVSLSAHRAPRTLADYVGQLR-ARDISV 68

Query: 454 FIAVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPDS- 284
            IA AG +  L   ++  T+ PVI  P     L  +  + +   +P G+  ATV   +S 
Sbjct: 69  VIAGAGLAAALPGTIAALTTLPVIGVPISGGALDGMDSLLAIAQMPPGVPVATVGLNNST 128

Query: 283 -AALMAAQIIGLQD 245
            AA++A QI+ L D
Sbjct: 129 NAAILAIQILALAD 142


>UniRef50_A4M8A1 Cluster:
           1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate
           (AIR) carboxylase; n=1; Petrotoga mobilis SJ95|Rep:
           1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate
           (AIR) carboxylase - Petrotoga mobilis SJ95
          Length = 139

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 31/112 (27%), Positives = 56/112 (50%), Gaps = 2/112 (1%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           KV++  GS +D+   +       E  +  D +V SAH+  +E  + +++       ++ I
Sbjct: 4   KVLLISGSQSDEIFVKTAIDLFEEWKISYDYKVFSAHRNLKELTKFIEELPSNEYCVI-I 62

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATV 299
           AVAG S  L  V++  T+ PV+  P     L  +  + S + +PSG+  AT+
Sbjct: 63  AVAGLSAALPGVIASLTNLPVVGVPRDVGPLNGIDALLSMVQMPSGVPVATM 114


>UniRef50_P21264 Cluster: Phosphoribosylaminoimidazole carboxylase;
           n=62; cellular organisms|Rep:
           Phosphoribosylaminoimidazole carboxylase - Saccharomyces
           cerevisiae (Baker's yeast)
          Length = 571

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 40/146 (27%), Positives = 66/146 (45%), Gaps = 4/146 (2%)
 Frame = -2

Query: 670 VKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRI 491
           V  +LD L+  +   V + MGS +D           ++ G+  ++ + SAH+ T   +  
Sbjct: 391 VAQKLD-LEAMVKPLVGIIMGSDSDLPVMSAACAVLKDFGVPFEVTIVSAHR-TPHRMSA 448

Query: 490 MQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSG 317
                   G    IA AG +  L  +++  T  PVI  P     L  V  + S + +P G
Sbjct: 449 YAISASKRGIKTIIAGAGGAAHLPGMVAAMTPLPVIGVPVKGSCLDGVDSLHSIVQMPRG 508

Query: 316 LGCATVIYPDS--AALMAAQIIGLQD 245
           +  ATV   +S  AAL+A +++G  D
Sbjct: 509 VPVATVAINNSTNAALLAVRLLGAYD 534


>UniRef50_Q55498 Cluster: Phosphoribosylaminoimidazole carboxylase
           catalytic subunit; n=200; cellular organisms|Rep:
           Phosphoribosylaminoimidazole carboxylase catalytic
           subunit - Synechocystis sp. (strain PCC 6803)
          Length = 176

 Score = 47.6 bits (108), Expect = 3e-04
 Identities = 35/127 (27%), Positives = 58/127 (45%), Gaps = 4/127 (3%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D            E  +  ++ + SAH+  E  +   Q      G  + IA
Sbjct: 8   VGIIMGSDSDLPTMAAAIAVCEEFAVPTEVAIISAHRTPERMVEYAQTAHQ-RGLRIIIA 66

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD--SAA 278
            AG +  L  +++  T  PVI  P  +  L  V  ++S + +P G+  ATV   +  +A 
Sbjct: 67  GAGGAAHLPGMVAALTPLPVIGVPVQTKTLQGVDSLYSIVQMPGGIPVATVAIGNAKNAG 126

Query: 277 LMAAQII 257
           L+A QI+
Sbjct: 127 LLAVQIL 133


>UniRef50_P15567 Cluster: Phosphoribosylaminoimidazole carboxylase;
           n=53; cellular organisms|Rep:
           Phosphoribosylaminoimidazole carboxylase -
           Schizosaccharomyces pombe (Fission yeast)
          Length = 552

 Score = 46.4 bits (105), Expect = 7e-04
 Identities = 39/138 (28%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
 Frame = -2

Query: 658 LDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQY 479
           LD   P     V + MGS +D    +  A    E  +  +L + SAH+ T + +    + 
Sbjct: 377 LDVKDPVESPVVGIIMGSDSDLSKMKDAAVILDEFKVPYELTIVSAHR-TPDRMVTYART 435

Query: 478 EDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCA 305
             + G  V IA AG +  L  +++  T  PVI  P     L  V  + S + +P G+  A
Sbjct: 436 AASRGLRVIIAGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGVPVA 495

Query: 304 TVIYPDS--AALMAAQII 257
           TV   +S  A ++A +I+
Sbjct: 496 TVAINNSQNAGILACRIL 513


>UniRef50_A7D0F6 Cluster: NCAIR mutase (PurE)-related protein; n=1;
           Halorubrum lacusprofundi ATCC 49239|Rep: NCAIR mutase
           (PurE)-related protein - Halorubrum lacusprofundi ATCC
           49239
          Length = 260

 Score = 43.6 bits (98), Expect = 0.005
 Identities = 30/94 (31%), Positives = 44/94 (46%)
 Frame = -2

Query: 655 DFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYE 476
           DF +P ++  V V     AD     + A  ARE+G  +D R+     A  +  RI+ Q +
Sbjct: 117 DFERPDLNATVAVVAAGTADAAVAGEAAVVAREIGATID-RIDDVGVANLD--RILDQRD 173

Query: 475 DTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCP 374
               A V +  AGR   L  V++G  + PVI  P
Sbjct: 174 RIREADVVVVAAGREGALPTVVAGLVAAPVIALP 207


>UniRef50_Q98FE6 Cluster: Phosphoribosylaminoimidazole carboxylase
           I; n=5; Proteobacteria|Rep: Phosphoribosylaminoimidazole
           carboxylase I - Rhizobium loti (Mesorhizobium loti)
          Length = 165

 Score = 43.2 bits (97), Expect = 0.007
 Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D    ++ A+    LG+     + SAH+ T + L    +     G  V IA
Sbjct: 8   VAIIMGSQSDWATMRQAAETLEALGVPHKRLIISAHR-TPDRLYEFAKGAKAAGYKVIIA 66

Query: 445 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLV-QD-IWSSLSVPSGLGCATVIY----PDS 284
            AG +  L  + +  T  PV   P  S  L  QD + S + +P+G+   T+        +
Sbjct: 67  GAGGAAHLPGMTAAMTPLPVFGVPVESKALSGQDSLLSIVQMPAGIPVGTLAIGKAGAAN 126

Query: 283 AALMAAQIIGLQD 245
           AAL+AA ++ L D
Sbjct: 127 AALLAAAVLALND 139


>UniRef50_Q6BIQ2 Cluster: Similar to CA4826|IPF1206 Candida albicans
           IPF1206 unknown function; n=1; Debaryomyces
           hansenii|Rep: Similar to CA4826|IPF1206 Candida albicans
           IPF1206 unknown function - Debaryomyces hansenii (Yeast)
           (Torulaspora hansenii)
          Length = 556

 Score = 36.3 bits (80), Expect = 0.80
 Identities = 25/76 (32%), Positives = 36/76 (47%), Gaps = 1/76 (1%)
 Frame = -2

Query: 511 TEETLRIMQQYEDTHGALV-FIAVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQDIWSS 335
           TE+  +I   Y  T+G +V FI  +   +   P L      P    PPP  K+ Q ++SS
Sbjct: 149 TEDFNKISVSYNLTNGEVVTFIYKSEEPSSSMPPLPNAYHSPYPQPPPPPQKIKQPLFSS 208

Query: 334 LSVPSGLGCATVIYPD 287
           L+  S L   + I PD
Sbjct: 209 LTGKSNLDPRSTIVPD 224


>UniRef50_A6CXW5 Cluster: Putative uncharacterized protein; n=1;
           Vibrio shilonii AK1|Rep: Putative uncharacterized
           protein - Vibrio shilonii AK1
          Length = 220

 Score = 35.5 bits (78), Expect = 1.4
 Identities = 24/84 (28%), Positives = 35/84 (41%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           + +  G  +D   C +I +     G+   L       A     R+    ED + A + IA
Sbjct: 89  IAIVSGGSSDTNICHEILRTLNYHGVSASLYEDVGVSAL---WRLTNALEDINKAKIIIA 145

Query: 445 VAGRSNGLGPVLSGNTSYPVINCP 374
           VAG    L  VL+G T  P+I  P
Sbjct: 146 VAGMEAALPTVLAGLTPRPIIAVP 169


>UniRef50_A4G5F2 Cluster: Universal stress protein; n=4;
           Herminiimonas arsenicoxydans|Rep: Universal stress
           protein - Herminiimonas arsenicoxydans
          Length = 143

 Score = 35.1 bits (77), Expect = 1.8
 Identities = 21/71 (29%), Positives = 37/71 (52%)
 Frame = -2

Query: 595 QEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGLGP 416
           +++  KIA  A  LG+D ++ V     A++E ++   +Y   H   +F+A  GR  GL  
Sbjct: 66  EKYVHKIATHAASLGVDAEVHVVEGTSASDEIIKAADKY---HCDAIFMASHGR-KGLDK 121

Query: 415 VLSGNTSYPVI 383
            L G+ +  V+
Sbjct: 122 FLLGSEAQKVL 132


>UniRef50_O28993 Cluster: Putative uncharacterized protein; n=1;
           Archaeoglobus fulgidus|Rep: Putative uncharacterized
           protein - Archaeoglobus fulgidus
          Length = 229

 Score = 35.1 bits (77), Expect = 1.8
 Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 4/89 (4%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDV----DLRVTSAHKATEETLRIMQQYEDTHGA 461
           KV +     +D    ++ A  A  LGL+V    D+ V   H+  E   RI ++  D+   
Sbjct: 91  KVAILTAGTSDIPVAEEAAVTAEFLGLEVLRFYDVGVAGLHRIVEPVKRIREENVDSA-- 148

Query: 460 LVFIAVAGRSNGLGPVLSGNTSYPVINCP 374
              I VAG    L  V++G    PVI  P
Sbjct: 149 ---IVVAGMEGALPSVIAGLVDVPVIAVP 174


>UniRef50_A7H038 Cluster: Ncair mutase; n=8; Bacteria|Rep: Ncair
           mutase - Campylobacter curvus 525.92
          Length = 248

 Score = 34.7 bits (76), Expect = 2.4
 Identities = 24/84 (28%), Positives = 38/84 (45%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           + +     +D    ++  + A+ LG  V  ++T    A     R+  + +D  GA V IA
Sbjct: 121 IAIISAGTSDMSVVEEAYETAKFLGNSVK-KITDVGVAGIH--RLFSKLDDIQGARVVIA 177

Query: 445 VAGRSNGLGPVLSGNTSYPVINCP 374
           VAG    L  V++G    PVI  P
Sbjct: 178 VAGMEGALPSVIAGLVKAPVIAVP 201


>UniRef50_Q8RJP6 Cluster: Putative uncharacterized protein; n=11;
           Xanthomonas|Rep: Putative uncharacterized protein -
           Xanthomonas euvesicatoria
          Length = 339

 Score = 33.5 bits (73), Expect = 5.6
 Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 3/110 (2%)
 Frame = -2

Query: 568 AARELGLDVDLR-VTSAHKATEETLRIMQQYEDTHGALV--FIAVAGRSNGLGPVLSGNT 398
           AAR L  ++ +    +A  A + T R++     T+G +    +  AGR  G+  VL+   
Sbjct: 123 AARLLASELKVAPYAAARDAIQATFRMVGMRSPTNGGVSDPHVTSAGRFYGMANVLTNLA 182

Query: 397 SYPVINCPPPSDKLVQDIWSSLSVPSGLGCATVIYPDSAALMAAQIIGLQ 248
           S  +     P     +  W+ L  P  +G AT +    AA+ AA  +GL+
Sbjct: 183 SNEL---EAPDFASARQRWAGLMSPFNMGEATRVVFQQAAVNAALNVGLE 229


>UniRef50_Q2ADF8 Cluster: Adenylyl cyclase class-3/4/guanylyl
           cyclase:CHASE2 precursor; n=1; Halothermothrix orenii H
           168|Rep: Adenylyl cyclase class-3/4/guanylyl
           cyclase:CHASE2 precursor - Halothermothrix orenii H 168
          Length = 582

 Score = 33.5 bits (73), Expect = 5.6
 Identities = 17/48 (35%), Positives = 28/48 (58%)
 Frame = -2

Query: 565 ARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGL 422
           AR +GLD+ L  +S  +A E+ ++++ QYE+    L  +A  G   GL
Sbjct: 92  ARAIGLDIILEASSGREADEKLVKVLSQYENV--VLPAVARVGLVRGL 137


>UniRef50_Q9YBE5 Cluster: PqqE homolog; n=4; Thermoprotei|Rep: PqqE
           homolog - Aeropyrum pernix
          Length = 389

 Score = 33.5 bits (73), Expect = 5.6
 Identities = 22/69 (31%), Positives = 35/69 (50%)
 Frame = -2

Query: 679 FAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEET 500
           F++V   LD + P +H K   F G+P   +   + A+ A E GLDV  R+T      ++ 
Sbjct: 135 FSYVGISLDSVDPGVHDK---FRGAPGAFKAAIRGARNALEEGLDVGFRLTITKYNLDDA 191

Query: 499 LRIMQQYED 473
            RI++   D
Sbjct: 192 PRIIRLASD 200


>UniRef50_Q8AAD6 Cluster: Indole-3-glycerol phosphate synthase; n=7;
           Bacteroidales|Rep: Indole-3-glycerol phosphate synthase
           - Bacteroides thetaiotaomicron
          Length = 260

 Score = 33.5 bits (73), Expect = 5.6
 Identities = 15/36 (41%), Positives = 24/36 (66%)
 Frame = -2

Query: 622 VVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHK 515
           V+ + +   QE CQ++A+ A ELGL+V L + SA +
Sbjct: 137 VLLIAAALKQEKCQELAEQAHELGLEVLLEIHSAEE 172


>UniRef50_P73194 Cluster: Slr1699 protein; n=1; Synechocystis sp.
           PCC 6803|Rep: Slr1699 protein - Synechocystis sp.
           (strain PCC 6803)
          Length = 282

 Score = 33.1 bits (72), Expect = 7.5
 Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 6/87 (6%)
 Frame = -2

Query: 577 IAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAV--AGRSNGLGPVLSG 404
           + K  R+L L VDL         E  L I + Y      L+  +     ++ GL P+L+ 
Sbjct: 151 VQKQLRQLNLQVDLNFEFTPSPEETNLLIAENYRVRRNLLIKFSNDDIDQTLGLRPILNQ 210

Query: 403 NTSYPVINCPPPSDKLV---QDI-WSS 335
            T+  V  CP P + L    QDI W +
Sbjct: 211 QTADLVAYCPLPGNHLTPLGQDIQWET 237


>UniRef50_A0RWQ1 Cluster: Phosphoribosylcarboxyaminoimidazole
           (NCAIR) mutase; n=1; Cenarchaeum symbiosum|Rep:
           Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase -
           Cenarchaeum symbiosum
          Length = 181

 Score = 33.1 bits (72), Expect = 7.5
 Identities = 24/85 (28%), Positives = 41/85 (48%)
 Frame = -2

Query: 628 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 449
           +V + MGS +D     + A+     G+  +  + SAH+ T E L    ++ +  G  V I
Sbjct: 8   EVGIIMGSSSDARIMLEAARVLDGFGVLHEDLIVSAHR-TPERLGDYARHAEEIGLRVII 66

Query: 448 AVAGRSNGLGPVLSGNTSYPVINCP 374
           A AG +  L  +++  T  PV+  P
Sbjct: 67  AGAGGAAHLPGMIASYTVVPVVGVP 91


>UniRef50_Q89GN0 Cluster: Blr6315 protein; n=1; Bradyrhizobium
           japonicum|Rep: Blr6315 protein - Bradyrhizobium
           japonicum
          Length = 790

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 15/41 (36%), Positives = 25/41 (60%)
 Frame = -2

Query: 598 DQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYE 476
           ++E  +++A+   + G D+D +   A KA+EE LRI Q  E
Sbjct: 563 ERERAEQLARDLAKAGRDLDAQTERASKASEEVLRIKQAGE 603


>UniRef50_Q87WE4 Cluster: Putative uncharacterized protein; n=1;
           Pseudomonas syringae pv. tomato|Rep: Putative
           uncharacterized protein - Pseudomonas syringae pv.
           tomato
          Length = 819

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
 Frame = -2

Query: 562 RELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGLGP---VLSGNTSY 392
           +++ L +D     + +  +ET  I Q++  T   LVF+A+   +  L      LSG  + 
Sbjct: 430 KQIILVLDNADQRSFEVQQETFLIAQEFASTRNLLVFVALRPSTFFLSKTTGALSGYQNK 489

Query: 391 PVINCPPPSDKLVQ 350
            +   PPP+D++VQ
Sbjct: 490 VLTISPPPADEVVQ 503


>UniRef50_A4IPG9 Cluster: NCAIR mutase (Pure)-related protein; n=9;
           Bacteria|Rep: NCAIR mutase (Pure)-related protein -
           Geobacillus thermodenitrificans (strain NG80-2)
          Length = 269

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 28/102 (27%), Positives = 41/102 (40%)
 Frame = -2

Query: 679 FAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEET 500
           F W+    D+++   H  + V     +D    ++ A  A  LG  V  R+     A    
Sbjct: 110 FYWISQ--DYVETKKHGYIAVVSAGTSDVPIAEEAAVTAELLGCKVK-RIYDVGVAGIH- 165

Query: 499 LRIMQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCP 374
            R++   E    + V I VAG    L  V+ G  S PVI  P
Sbjct: 166 -RLLDNIEMIERSSVVIVVAGMEGALASVVGGLVSKPVIAVP 206


>UniRef50_Q9VIK2 Cluster: CG9317-PA, isoform A; n=7;
           Endopterygota|Rep: CG9317-PA, isoform A - Drosophila
           melanogaster (Fruit fly)
          Length = 674

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 14/38 (36%), Positives = 20/38 (52%)
 Frame = -2

Query: 403 NTSYPVINCPPPSDKLVQDIWSSLSVPSGLGCATVIYP 290
           N S+P+I CP   +     +WSS+ +   L C   IYP
Sbjct: 141 NASWPLIKCPQGWEYNTSVVWSSIVIDFDLVCDQDIYP 178


>UniRef50_A7DMC3 Cluster: Phosphoribosylaminoimidazole carboxylase,
           catalytic subunit; n=1; Candidatus Nitrosopumilus
           maritimus SCM1|Rep: Phosphoribosylaminoimidazole
           carboxylase, catalytic subunit - Candidatus
           Nitrosopumilus maritimus SCM1
          Length = 191

 Score = 32.7 bits (71), Expect = 9.9
 Identities = 23/84 (27%), Positives = 41/84 (48%)
 Frame = -2

Query: 625 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 446
           V + MGS +D    +  A+   +  +  + ++ SAH+ T   L    Q+ +  G  + IA
Sbjct: 9   VGIIMGSSSDSRIMKGAAEILDDFKVKHEDQIISAHR-TPARLAEYAQHAEKMGFDIIIA 67

Query: 445 VAGRSNGLGPVLSGNTSYPVINCP 374
            AG +  L  +++ +T  PVI  P
Sbjct: 68  GAGGAAHLPGMIASHTVIPVIGVP 91


  Database: uniref50
    Posted date:  Oct 5, 2007 11:19 AM
  Number of letters in database: 575,637,011
  Number of sequences in database:  1,657,284
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.279   0.0580    0.190 


Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 776,106,473
Number of Sequences: 1657284
Number of extensions: 17363408
Number of successful extensions: 43040
Number of sequences better than 10.0: 52
Number of HSP's better than 10.0 without gapping: 40765
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 42948
length of database: 575,637,011
effective HSP length: 99
effective length of database: 411,565,895
effective search space used: 61323318355
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)

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