Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fner10d16f
(602 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:... 235 4e-61
UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole car... 166 3e-40
UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila melanogaste... 127 2e-28
UniRef50_Q73PV9 Cluster: Phosphoribosylaminoimidazole carboxylas... 107 2e-22
UniRef50_O28997 Cluster: Phosphoribosylaminoimidazole carboxylas... 106 5e-22
UniRef50_A5UWC5 Cluster: Phosphoribosylaminoimidazolesuccinocarb... 73 5e-12
UniRef50_Q1MPV1 Cluster: Phosphoribosylcarboxyaminoimidazole (NC... 68 2e-10
UniRef50_Q83AA3 Cluster: Phosphoribosylaminoimidazole carboxylas... 65 1e-09
UniRef50_P41654 Cluster: Probable phosphoribosylaminoimidazole c... 64 2e-09
UniRef50_A5G876 Cluster: Phosphoribosylaminoimidazole carboxylas... 64 3e-09
UniRef50_Q8A4S9 Cluster: Phosphoribosylaminoimidazole carboxylas... 61 2e-08
UniRef50_Q74AP6 Cluster: Phosphoribosylaminoimidazole carboxylas... 60 3e-08
UniRef50_O58058 Cluster: Phosphoribosylaminoimidazole carboxylas... 59 7e-08
UniRef50_Q2NEA3 Cluster: PurE; n=3; Archaea|Rep: PurE - Methanos... 59 9e-08
UniRef50_Q8PV25 Cluster: Phosphoribosylaminoimidazole carboxylas... 58 1e-07
UniRef50_Q7M7S1 Cluster: PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLAS... 56 5e-07
UniRef50_Q94IQ2 Cluster: Phosphoribosylaminoimidazole-succinocar... 56 6e-07
UniRef50_P22348 Cluster: Probable phosphoribosylaminoimidazole c... 56 6e-07
UniRef50_Q8XMK7 Cluster: Phosphoribosylaminoimidazole carboxylas... 55 1e-06
UniRef50_A0LLY4 Cluster: Phosphoribosylaminoimidazole carboxylas... 54 3e-06
UniRef50_A2SPX9 Cluster: 1-(5-phosphoribosyl)-5-amino-4-imidazol... 54 3e-06
UniRef50_Q11CU3 Cluster: Phosphoribosylaminoimidazole carboxylas... 53 6e-06
UniRef50_Q5XEE9 Cluster: Phosphoribosylaminoimidazole carboxylas... 52 1e-05
UniRef50_Q4AJE5 Cluster: 1-(5-Phosphoribosyl)-5-amino-4-imidazol... 52 1e-05
UniRef50_A0JU62 Cluster: Phosphoribosylaminoimidazole carboxylas... 52 1e-05
UniRef50_P96880 Cluster: Phosphoribosylaminoimidazole carboxylas... 52 1e-05
UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep: LO... 51 2e-05
UniRef50_P72157 Cluster: Phosphoribosylaminoimidazole carboxylas... 51 2e-05
UniRef50_Q93J44 Cluster: Phosphoribosylaminoimidazole carboxylas... 51 2e-05
UniRef50_A1T5T8 Cluster: Phosphoribosylaminoimidazole carboxylas... 49 1e-04
UniRef50_Q2J4S5 Cluster: Phosphoribosylaminoimidazole carboxylas... 48 2e-04
UniRef50_A4M8A1 Cluster: 1-(5-phosphoribosyl)-5-amino-4-imidazol... 48 2e-04
UniRef50_P21264 Cluster: Phosphoribosylaminoimidazole carboxylas... 48 2e-04
UniRef50_Q55498 Cluster: Phosphoribosylaminoimidazole carboxylas... 48 2e-04
UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylas... 46 5e-04
UniRef50_P15567 Cluster: Phosphoribosylaminoimidazole carboxylas... 46 5e-04
UniRef50_A7D0F6 Cluster: NCAIR mutase (PurE)-related protein; n=... 44 0.003
UniRef50_Q98FE6 Cluster: Phosphoribosylaminoimidazole carboxylas... 43 0.005
UniRef50_Q5FIU8 Cluster: Phosphoribosylaminoimidazole-succinocar... 40 0.034
UniRef50_Q6BIQ2 Cluster: Similar to CA4826|IPF1206 Candida albic... 38 0.18
UniRef50_P12046 Cluster: Phosphoribosylaminoimidazole-succinocar... 36 0.56
UniRef50_A6CXW5 Cluster: Putative uncharacterized protein; n=1; ... 36 0.97
UniRef50_O57978 Cluster: Phosphoribosylaminoimidazole-succinocar... 36 0.97
UniRef50_A4G5F2 Cluster: Universal stress protein; n=4; Herminii... 35 1.3
UniRef50_A3S2A4 Cluster: ATP-dependent exoDNAse alpha subunit; n... 35 1.3
UniRef50_Q9YBE5 Cluster: PqqE homolog; n=4; Thermoprotei|Rep: Pq... 35 1.3
UniRef50_O28993 Cluster: Putative uncharacterized protein; n=1; ... 35 1.3
UniRef50_Q8AAD6 Cluster: Indole-3-glycerol phosphate synthase; n... 35 1.3
UniRef50_Q58987 Cluster: Phosphoribosylaminoimidazole-succinocar... 35 1.3
UniRef50_A7H038 Cluster: Ncair mutase; n=8; Bacteria|Rep: Ncair ... 35 1.7
UniRef50_A4BQ22 Cluster: Putative uncharacterized protein; n=1; ... 35 1.7
UniRef50_Q92AN6 Cluster: Phosphoribosylaminoimidazole-succinocar... 35 1.7
UniRef50_Q18IR2 Cluster: NCAIR mutase (PurE)-related protein; n=... 34 2.3
UniRef50_Q2SGQ5 Cluster: Glycosyltransferase; n=1; Hahella cheju... 34 3.0
UniRef50_UPI0000DB74A8 Cluster: PREDICTED: similar to CG5199-PA;... 33 3.9
UniRef50_Q8RJP6 Cluster: Putative uncharacterized protein; n=11;... 33 3.9
UniRef50_Q2ADF8 Cluster: Adenylyl cyclase class-3/4/guanylyl cyc... 33 3.9
UniRef50_Q7K274 Cluster: LD15586p; n=6; Diptera|Rep: LD15586p - ... 33 3.9
UniRef50_P73194 Cluster: Slr1699 protein; n=1; Synechocystis sp.... 33 5.2
UniRef50_A0RWQ1 Cluster: Phosphoribosylcarboxyaminoimidazole (NC... 33 5.2
UniRef50_Q89GN0 Cluster: Blr6315 protein; n=1; Bradyrhizobium ja... 33 6.9
UniRef50_Q87WE4 Cluster: Putative uncharacterized protein; n=1; ... 33 6.9
UniRef50_A4IPG9 Cluster: NCAIR mutase (Pure)-related protein; n=... 33 6.9
UniRef50_Q9VIK2 Cluster: CG9317-PA, isoform A; n=7; Endopterygot... 33 6.9
UniRef50_A7DMC3 Cluster: Phosphoribosylaminoimidazole carboxylas... 33 6.9
UniRef50_Q6FPI5 Cluster: Putative guanine nucleotide-exchange fa... 33 6.9
UniRef50_A7AVF9 Cluster: Translation factor Sua5, putative; n=1;... 32 9.1
UniRef50_Q2GSZ3 Cluster: Putative uncharacterized protein; n=1; ... 32 9.1
UniRef50_Q0UH42 Cluster: Putative uncharacterized protein; n=1; ... 32 9.1
>UniRef50_P22234 Cluster: Multifunctional protein ADE2 [Includes:
Phosphoribosylaminoimidazole- succinocarboxamide
synthase (EC 6.3.2.6) (SAICAR synthetase);
Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
(AIR carboxylase) (AIRC)]; n=60; Eumetazoa|Rep:
Multifunctional protein ADE2 [Includes:
Phosphoribosylaminoimidazole- succinocarboxamide
synthase (EC 6.3.2.6) (SAICAR synthetase);
Phosphoribosylaminoimidazole carboxylase (EC 4.1.1.21)
(AIR carboxylase) (AIRC)] - Homo sapiens (Human)
Length = 425
Score = 235 bits (576), Expect = 4e-61
Identities = 118/203 (58%), Positives = 145/203 (71%), Gaps = 3/203 (1%)
Frame = +2
Query: 2 GVD-TEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYRNLTTVTAADLDTVKRNFAWVKD 178
GVD T IVLADVID+DSWRLWPSGD+ DKQ YR+L VT L VK+NF WV +
Sbjct: 195 GVDVTTKEIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVAE 254
Query: 179 QLDFL-KPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQ 355
+++ L K +VVV MGS +D HC+KI KA G+ +LRVTSAHK +ETLRI
Sbjct: 255 RVELLLKSESQCRVVVLMGSTSDLGHCEKIKKACGNFGIPCELRVTSAHKGPDETLRIKA 314
Query: 356 QYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPP-PSDKLVQDIWSSLSVPSGLGC 532
+YE VF+AVAGRSNGLGPV+SGNT+YPVI+CPP D VQD+WSSL +PSGLGC
Sbjct: 315 EYEGDGIPTVFVAVAGRSNGLGPVMSGNTAYPVISCPPLTPDWGVQDVWSSLRLPSGLGC 374
Query: 533 ATVIYPDSAALMAAQIIGLQDYL 601
+TV+ P+ +A AAQI GL ++L
Sbjct: 375 STVLSPEGSAQFAAQIFGLSNHL 397
>UniRef50_UPI0000F33553 Cluster: phosphoribosylaminoimidazole
carboxylase, phosphoribosylaminoimidazole
succinocarboxamide synthetase; n=2; Coelomata|Rep:
phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoimidazole succinocarboxamide
synthetase - Bos Taurus
Length = 402
Score = 166 bits (404), Expect = 3e-40
Identities = 98/205 (47%), Positives = 124/205 (60%), Gaps = 5/205 (2%)
Frame = +2
Query: 2 GVDT-EGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYRNLTTVTAADLDTVKRNFAWVKD 178
GVD IVLADVID+DSWRLWPSGD+ DKQ YR+L VT L VK+NF WV +
Sbjct: 198 GVDVITREIVLADVIDNDSWRLWPSGDRSQQKDKQSYRDLKEVTPEGLQMVKKNFEWVAE 257
Query: 179 QLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQ 358
+++ L K F + +++ A HK +ETLRI +
Sbjct: 258 RVEVL----IRKATFF--------YIERVTSA---------------HKGPDETLRIKAE 290
Query: 359 YEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPP-PSDKLVQDIWSSLSVPS---GL 526
YE VF+AVAGRSNGLGPVLSGNT+YPVI+CPP D QD+WSSL +PS GL
Sbjct: 291 YEGDGIPTVFVAVAGRSNGLGPVLSGNTAYPVISCPPLTPDWGAQDVWSSLRLPSEPIGL 350
Query: 527 GCATVIYPDSAALMAAQIIGLQDYL 601
GC+T++ P+ +A AAQI GL ++L
Sbjct: 351 GCSTILSPEGSAQFAAQIFGLNNHL 375
>UniRef50_Q9VK80 Cluster: CG17024-PA; n=1; Drosophila
melanogaster|Rep: CG17024-PA - Drosophila melanogaster
(Fruit fly)
Length = 395
Score = 127 bits (306), Expect = 2e-28
Identities = 79/201 (39%), Positives = 113/201 (56%), Gaps = 1/201 (0%)
Frame = +2
Query: 2 GVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYRNLTTVTAADLDTVKRNFAWVKDQ 181
GVD +G+I+LAD+IDSD+WR+WP+GDKRLMVDK VY NL TVT +DL+TVKRN++WV +Q
Sbjct: 197 GVDEDGNILLADIIDSDTWRIWPAGDKRLMVDKTVYINLDTVTDSDLNTVKRNYSWVIEQ 256
Query: 182 LDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQY 361
L + P H VV+ C ++ E L++ +A L
Sbjct: 257 LSSIAPPQDHLVVIL---------CVLFSENPEEA-----LQILRTFEAVINNL------ 296
Query: 362 EDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPP-PSDKLVQDIWSSLSVPSGLGCAT 538
VF+ V R N L V+S NTS+PVINC P SD + ++WS+ + S
Sbjct: 297 -------VFVTVDERLNSLANVISANTSFPVINCTPIQSDTMFMNMWSNSNPTSD----- 344
Query: 539 VIYPDSAALMAAQIIGLQDYL 601
P++AA A ++ L +++
Sbjct: 345 ---PEAAAKHVASLLSLGNFM 362
>UniRef50_Q73PV9 Cluster: Phosphoribosylaminoimidazole carboxylase,
PurE protein; n=1; Treponema denticola|Rep:
Phosphoribosylaminoimidazole carboxylase, PurE protein -
Treponema denticola
Length = 159
Score = 107 bits (258), Expect = 2e-22
Identities = 52/128 (40%), Positives = 77/128 (60%), Gaps = 1/128 (0%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V++ MGS +D H +KIA + G++ +R+ SAHK E + ++++YE ++I
Sbjct: 5 VIILMGSSSDMGHAEKIASELKTFGIEYAIRIGSAHKTAEHVVSMLKEYEALDRPKLYIT 64
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLV-QDIWSSLSVPSGLGCATVIYPDSAALMA 571
+AGRSN L + G I CPPPSD DI+SSL +PSG+ A V+ P +AAL+A
Sbjct: 65 IAGRSNALSGFVDGFVKGATIACPPPSDSFAGADIYSSLRMPSGISPALVLEPKNAALLA 124
Query: 572 AQIIGLQD 595
A+I L D
Sbjct: 125 ARIFSLYD 132
>UniRef50_O28997 Cluster: Phosphoribosylaminoimidazole carboxylase
catalytic subunit; n=1; Archaeoglobus fulgidus|Rep:
Phosphoribosylaminoimidazole carboxylase catalytic
subunit - Archaeoglobus fulgidus
Length = 180
Score = 106 bits (254), Expect = 5e-22
Identities = 56/129 (43%), Positives = 81/129 (62%), Gaps = 1/129 (0%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
K V+ MGS +D ++ +KIA + G+D +R+ SAHK E+ L I+++YE +VF+
Sbjct: 28 KAVIIMGSKSDLDYSKKIASKLADFGIDAVMRIASAHKTPEKVLEIIKEYEKED--VVFV 85
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL-VQDIWSSLSVPSGLGCATVIYPDSAALM 568
VAGRSN L + NTS PVI PP SDK DI+SS+ +PSG+ V+ ++AAL
Sbjct: 86 TVAGRSNALSGFVDANTSKPVIASPPYSDKFGGADIFSSIRMPSGVAPMLVLEAENAALA 145
Query: 569 AAQIIGLQD 595
A+I L+D
Sbjct: 146 VAKIFALKD 154
>UniRef50_A5UWC5 Cluster:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase;
n=5; Chloroflexi (class)|Rep:
Phosphoribosylaminoimidazolesuccinocarboxamide synthase
- Roseiflexus sp. RS-1
Length = 249
Score = 72.9 bits (171), Expect = 5e-12
Identities = 32/62 (51%), Positives = 43/62 (69%)
Frame = +2
Query: 2 GVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYRNLTTVTAADLDTVKRNFAWVKDQ 181
G DT G +++ADVID+DSWR+WP G K M+DKQVYRN+ VT L+ V+R + V +
Sbjct: 183 GRDTSGRLLVADVIDNDSWRIWPGGVKERMLDKQVYRNMPVVTDEGLEQVRRLYEEVAQR 242
Query: 182 LD 187
D
Sbjct: 243 TD 244
>UniRef50_Q1MPV1 Cluster: Phosphoribosylcarboxyaminoimidazole
(NCAIR) mutase; n=1; Lawsonia intracellularis
PHE/MN1-00|Rep: Phosphoribosylcarboxyaminoimidazole
(NCAIR) mutase - Lawsonia intracellularis (strain
PHE/MN1-00)
Length = 171
Score = 67.7 bits (158), Expect = 2e-10
Identities = 44/136 (32%), Positives = 68/136 (50%), Gaps = 6/136 (4%)
Frame = +2
Query: 206 HHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALV 385
H KV +F+GSP+D+ + +L + V+SAH+ E T ++ E +G V
Sbjct: 3 HVKVAIFIGSPSDESIVSPCTEILTQLNIPYIFTVSSAHRTPERTAELIDSLE-ANGCEV 61
Query: 386 FIAVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD-- 553
FI AG + L ++ T PVI P S L + + +++ +PSG ATV
Sbjct: 62 FICAAGMAAHLAGAVAARTLKPVIGIPITSSSLGGMDALLATVQMPSGYPVATVALDTAG 121
Query: 554 --SAALMAAQIIGLQD 595
+AA +AAQI+ L D
Sbjct: 122 ARNAAWLAAQILALHD 137
>UniRef50_Q83AA3 Cluster: Phosphoribosylaminoimidazole carboxylase,
catalytic subunit; n=9; Proteobacteria|Rep:
Phosphoribosylaminoimidazole carboxylase, catalytic
subunit - Coxiella burnetii
Length = 166
Score = 64.9 bits (151), Expect = 1e-09
Identities = 41/133 (30%), Positives = 67/133 (50%), Gaps = 6/133 (4%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D + + LG+ + + SAH+ +ET+ ++ D G VFIA
Sbjct: 6 VAILMGSDSDLSTMETAFTELKSLGIPFEAHILSAHRTPKETVEFVEN-ADNRGCAVFIA 64
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSG--LGCATV--IYPDS 556
AG + L ++ +T PVI P L + + S++ +P G + C + +
Sbjct: 65 AAGLAAHLAGTIAAHTLKPVIGVPMAGGSLGGLDALLSTVQMPGGVPVACTAIGKAGAKN 124
Query: 557 AALMAAQIIGLQD 595
AA++AAQII LQD
Sbjct: 125 AAILAAQIIALQD 137
>UniRef50_P41654 Cluster: Probable phosphoribosylaminoimidazole
carboxylase; n=2; Methanothermobacter thermautotrophicus
str. Delta H|Rep: Probable phosphoribosylaminoimidazole
carboxylase - Methanobacterium thermoautotrophicum
Length = 334
Score = 64.1 bits (149), Expect = 2e-09
Identities = 44/131 (33%), Positives = 67/131 (51%), Gaps = 3/131 (2%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
+V++ +GS +D +K + EL + DLRV SAH+ E+ I+ + G VFI
Sbjct: 4 RVMILLGSASDFRIAEKAMEIFEELRIPYDLRVASAHRTHEKVKAIVSEAVKA-GVEVFI 62
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQD---IWSSLSVPSGLGCATVIYPDSAA 562
+AG S L ++S NT PVI P D S + P+ + V ++AA
Sbjct: 63 GIAGLSAHLPGMISANTHRPVIGVPVDVKLGGLDALFACSQMPFPAPVATVGVDRGENAA 122
Query: 563 LMAAQIIGLQD 595
++AAQIIG+ D
Sbjct: 123 ILAAQIIGIGD 133
Score = 46.4 bits (105), Expect = 5e-04
Identities = 36/130 (27%), Positives = 65/130 (50%), Gaps = 3/130 (2%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V V GS +D + +K +G+ DL V S + E R +++ E+ +FIA
Sbjct: 191 VSVIPGSYSDMKIAKKTTMFLERMGISYDLNVISPIRYPERFERYLEKMENVK---LFIA 247
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQD-IWSSLSVPSGLGCATVIYPD--SAAL 565
++G S + + + PVI P P D + S +++P G+ TV + +AA+
Sbjct: 248 ISGLSAHVTGAVVALSDRPVIGVPCPLKMNGWDSLLSMINMPPGVPVGTVGVGNGGNAAI 307
Query: 566 MAAQIIGLQD 595
+AA+++G+ D
Sbjct: 308 LAAEMLGIYD 317
>UniRef50_A5G876 Cluster: Phosphoribosylaminoimidazole carboxylase,
catalytic subunit; n=5; Bacteria|Rep:
Phosphoribosylaminoimidazole carboxylase, catalytic
subunit - Geobacter uraniumreducens Rf4
Length = 168
Score = 63.7 bits (148), Expect = 3e-09
Identities = 42/134 (31%), Positives = 71/134 (52%), Gaps = 6/134 (4%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
+V++ MGS +D + AK E + ++R++SAH++ T + + ED G V I
Sbjct: 5 QVLIVMGSDSDLPVMGEAAKVLTEFDVPFEMRISSAHRSPRRTGLLASEAED-RGVKVVI 63
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIY----PD 553
A AG + L V++ T+ PVI P L V ++S++ +P G+ AT+
Sbjct: 64 AGAGMAAHLAGVVAAETTLPVIGVPIGGGALNGVDALYSTVQMPGGIPVATMAIGRAGAK 123
Query: 554 SAALMAAQIIGLQD 595
+AA++A QI+ L D
Sbjct: 124 NAAILAVQILALAD 137
>UniRef50_Q8A4S9 Cluster: Phosphoribosylaminoimidazole carboxylase;
n=4; Bacteroides|Rep: Phosphoribosylaminoimidazole
carboxylase - Bacteroides thetaiotaomicron
Length = 171
Score = 60.9 bits (141), Expect = 2e-08
Identities = 40/131 (30%), Positives = 67/131 (51%), Gaps = 4/131 (3%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D +K A+ ++ + ++ SAH+ T E + + + G V IA
Sbjct: 7 VSIIMGSTSDLPVMEKAAQLLNDMHVPFEMNALSAHR-TPEAVEEFAKNARSRGIKVIIA 65
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD--SAA 562
AG + L V++ NT+ PVI P L V ++S + +P G+ ATV +AA
Sbjct: 66 AAGMAAALPGVIAANTTLPVIGVPVKGSVLDGVDALYSIIQMPPGIPVATVAINGAMNAA 125
Query: 563 LMAAQIIGLQD 595
++A Q++ L D
Sbjct: 126 ILAIQMLALSD 136
>UniRef50_Q74AP6 Cluster: Phosphoribosylaminoimidazole carboxylase,
catalytic subunit; n=1; Geobacter sulfurreducens|Rep:
Phosphoribosylaminoimidazole carboxylase, catalytic
subunit - Geobacter sulfurreducens
Length = 183
Score = 60.5 bits (140), Expect = 3e-08
Identities = 41/130 (31%), Positives = 67/130 (51%), Gaps = 4/130 (3%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + GSP D K+ ELG+ ++ V SAH+ ++ L + + G V I
Sbjct: 20 VGILTGSPNDLPTVVKVRDTLTELGIPSEIVVASAHRTPDKVLAYLDR-AHKEGVQVLIG 78
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPDS--AA 562
AG + L V++G+T PVI P + L + + S++ +P G+ ATV S AA
Sbjct: 79 CAGVAAHLAGVIAGHTRLPVIGLPLGNGPLSGMDSLLSTVQMPPGVPVATVAIDGSRNAA 138
Query: 563 LMAAQIIGLQ 592
++AA+I+ L+
Sbjct: 139 MLAARILALK 148
>UniRef50_O58058 Cluster: Phosphoribosylaminoimidazole carboxylase
catalytic subunit; n=94; cellular organisms|Rep:
Phosphoribosylaminoimidazole carboxylase catalytic
subunit - Pyrococcus horikoshii
Length = 177
Score = 59.3 bits (137), Expect = 7e-08
Identities = 40/130 (30%), Positives = 69/130 (53%), Gaps = 4/130 (3%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D ++ A+ E G+ ++ + SAH+ E ++ E+ G V IA
Sbjct: 12 VGIIMGSDSDLPVMKEAARILEEFGVPYEITIISAHRTPERAYEYAKKAEE-RGIEVIIA 70
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD--SAA 562
AG + L +++ T PVI P S L + + S + +PSG+ ATV + +AA
Sbjct: 71 GAGGAAHLPGIIASLTVLPVIGVPIKSKALNGLDSLLSIVQMPSGIPVATVAIDNAKNAA 130
Query: 563 LMAAQIIGLQ 592
L+A +I+G++
Sbjct: 131 LLALRILGIK 140
>UniRef50_Q2NEA3 Cluster: PurE; n=3; Archaea|Rep: PurE -
Methanosphaera stadtmanae (strain DSM 3091)
Length = 354
Score = 58.8 bits (136), Expect = 9e-08
Identities = 44/132 (33%), Positives = 67/132 (50%), Gaps = 4/132 (3%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
KV++ +GS +D + +K K ++ + DLRV SAH+ IM Y D G VFI
Sbjct: 19 KVMIILGSGSDYKIAEKTVKVFEQMKVPYDLRVASAHRTHNRIKDIMTNYVD--GIEVFI 76
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCAT--VIYPDSA 559
+AG S L V++ T+ PVI P + K+ + + S + G AT + ++A
Sbjct: 77 GIAGLSAHLPGVIASYTTKPVI-AVPVNGKIEGLDALLSCTEMQLGTPVATMGIDRGENA 135
Query: 560 ALMAAQIIGLQD 595
A +A QII D
Sbjct: 136 AWLACQIIACND 147
>UniRef50_Q8PV25 Cluster: Phosphoribosylaminoimidazole carboxylase;
n=5; cellular organisms|Rep:
Phosphoribosylaminoimidazole carboxylase -
Methanosarcina mazei (Methanosarcina frisia)
Length = 169
Score = 58.4 bits (135), Expect = 1e-07
Identities = 37/130 (28%), Positives = 67/130 (51%), Gaps = 3/130 (2%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
VV+ +GS +D+E +K + G++ + V SAH+ I++ T FIA
Sbjct: 4 VVIILGSKSDKEVARKATEVFDRFGIEYTITVASAHRTPARLAEIIETAHKT-DVKAFIA 62
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSD-KLVQDIWSSLSVPSGL--GCATVIYPDSAAL 565
+AG S L V++ +T PVI P S + + S +P+G+ C + D+AA+
Sbjct: 63 IAGLSAHLPGVVASSTIKPVIGVPVNSALDGIDALLSIAQMPTGIPVACVGIGRGDNAAI 122
Query: 566 MAAQIIGLQD 595
+A Q++ +++
Sbjct: 123 LAVQLLAVEN 132
>UniRef50_Q7M7S1 Cluster: PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE
CATALYTIC SUBUNIT; n=19; delta/epsilon subdivisions|Rep:
PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC
SUBUNIT - Wolinella succinogenes
Length = 164
Score = 56.4 bits (130), Expect = 5e-07
Identities = 36/124 (29%), Positives = 65/124 (52%), Gaps = 2/124 (1%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D E ++ A+ ++ + ++ ++SAH++ T + + E GA VFIA
Sbjct: 4 VSILMGSKSDAEVMRECAEIFKKFDVPYEMIISSAHRSPVRTKEYVLEAE-ARGAKVFIA 62
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPDSAALM 568
AG + L +S T+ PVI P L + + S++ +PSG+ TV + A+
Sbjct: 63 AAGMAAHLAGAISSMTTKPVIGVPMGGGTLGGLDALLSTVQMPSGMPVGTVAIGKTGAVN 122
Query: 569 AAQI 580
+A +
Sbjct: 123 SAYL 126
>UniRef50_Q94IQ2 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=1; Crypthecodinium cohnii|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Crypthecodinium cohnii (Dinoflagellate)
Length = 522
Score = 56.0 bits (129), Expect = 6e-07
Identities = 30/121 (24%), Positives = 58/121 (47%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V++ GS +D H + + K + + +R+ SAHK +++Q Y + ++ +
Sbjct: 356 VIIAAGSDSDMPHLETLKKELAKFKIPSQIRICSAHKQPGRLEQLIQAYNKSVEPIMLVG 415
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQDIWSSLSVPSGLGCATVIYPDSAALMAA 574
AG ++ L S + ++PV++CPP + L+ P G A ++ P + AA
Sbjct: 416 CAGGTDALSGTASYSATFPVVSCPPDGMNS-----TCLTNPPGSSNAFIVKPANVGKFAA 470
Query: 575 Q 577
Q
Sbjct: 471 Q 471
>UniRef50_P22348 Cluster: Probable phosphoribosylaminoimidazole
carboxylase; n=9; Euryarchaeota|Rep: Probable
phosphoribosylaminoimidazole carboxylase -
Methanobrevibacter smithii
Length = 339
Score = 56.0 bits (129), Expect = 6e-07
Identities = 41/131 (31%), Positives = 67/131 (51%), Gaps = 3/131 (2%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
KV++ +GS +D +K K +L + L++ SAH+ T + +R + G VFI
Sbjct: 4 KVMIILGSGSDIAIAEKSMKILEKLEIPYSLKIASAHR-TPDLVRELVVQGTNAGIKVFI 62
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQD-IWSSLSVPSGLGCATVIYP--DSAA 562
+AG + L ++ T PVI P D ++SS+ +P ATV D+ A
Sbjct: 63 GIAGLAAHLPGAIAAYTHKPVIGVPVDVKVSGLDALYSSVQMPYPSPVATVGIDRGDNGA 122
Query: 563 LMAAQIIGLQD 595
++AA+I+GL D
Sbjct: 123 ILAARILGLYD 133
Score = 34.7 bits (76), Expect = 1.7
Identities = 30/131 (22%), Positives = 66/131 (50%), Gaps = 3/131 (2%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDT-HGALVF 388
+VV+ +G D +K++ L + D++V ++ ++ + Y +T A +F
Sbjct: 196 EVVIIVGRHTDLITGKKVSVTLDRLKIPHDMQVICPIRSGKK----FRAYVNTMKNAKIF 251
Query: 389 IAVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQDIWSSLSVPSGLGCATVIYPD--SAA 562
I + S+ + L G T PVI P ++ + S++++P G+ ATV + +AA
Sbjct: 252 IGINSNSSQVSGGLVGLTEKPVIGVPCENELGNNYLLSTVNMPPGVPVATVGVNNGRNAA 311
Query: 563 LMAAQIIGLQD 595
+++ +I+ + +
Sbjct: 312 VLSGEILSINN 322
>UniRef50_Q8XMK7 Cluster: Phosphoribosylaminoimidazole carboxylase
catalytic subunit; n=11; Clostridium|Rep:
Phosphoribosylaminoimidazole carboxylase catalytic
subunit - Clostridium perfringens
Length = 159
Score = 54.8 bits (126), Expect = 1e-06
Identities = 38/130 (29%), Positives = 67/130 (51%), Gaps = 3/130 (2%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
KV +F GS +D + + A +E G+ + + SAH+ E+ + +++ E G V I
Sbjct: 2 KVAIFFGSKSDIDVMKGAGNALKEFGIPYNAYILSAHRVPEKLIETLEKIE-KEGCEVII 60
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQD-IWSSLSVPSGLGCATVIYPDS--AA 562
A AG + L V++ +T PVI P + D + S + +P + ATV +S A
Sbjct: 61 AGAGLAAHLPGVIASHTILPVIGVPVRAAVEGMDALLSIVQMPKSIPVATVGINNSYNAG 120
Query: 563 LMAAQIIGLQ 592
++A Q++ L+
Sbjct: 121 MLAVQMLSLK 130
>UniRef50_A0LLY4 Cluster: Phosphoribosylaminoimidazole carboxylase,
catalytic subunit; n=1; Syntrophobacter fumaroxidans
MPOB|Rep: Phosphoribosylaminoimidazole carboxylase,
catalytic subunit - Syntrophobacter fumaroxidans (strain
DSM 10017 / MPOB)
Length = 180
Score = 54.0 bits (124), Expect = 3e-06
Identities = 39/134 (29%), Positives = 66/134 (49%), Gaps = 6/134 (4%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
+V + MGS +D + + + + ++R+ SAH++ +ET R G V I
Sbjct: 9 RVGILMGSESDLSVMESAFRILDDFEVPYEVRILSAHRSPDETARYADS-AGQRGVQVLI 67
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD---- 553
A AG + L V++ T+ PVI P S L + + +++ +P G+ AT+
Sbjct: 68 AGAGWAAHLAGVVASRTTLPVIGVPIDSSPLQGMDALLATVQMPPGIPVATMCIGRGGAL 127
Query: 554 SAALMAAQIIGLQD 595
+AAL A QI+ L D
Sbjct: 128 NAALFALQILALND 141
>UniRef50_A2SPX9 Cluster:
1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate
(AIR) carboxylase; n=1; Methanocorpusculum labreanum
Z|Rep:
1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate
(AIR) carboxylase - Methanocorpusculum labreanum (strain
ATCC 43576 / DSM 4855 / Z)
Length = 129
Score = 53.6 bits (123), Expect = 3e-06
Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 5/130 (3%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
+V V GS +DQ K + + D++ SAH+ ++ + +Y + AL+FI
Sbjct: 3 EVAVIAGSVSDQAIVDKATAVLQSYNISFDVQFISAHRDADK----LDEYVKSSDALIFI 58
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKLVQDIWSSLSV---PSG--LGCATVIYPDS 556
+AG S L V++ T PVI P S K+ + + LS+ P G + C V ++
Sbjct: 59 CIAGMSAALPGVVAARTKKPVIGV-PVSGKIAGGLDALLSIAQMPKGVPVACMAVDGGEN 117
Query: 557 AALMAAQIIG 586
A AA+I+G
Sbjct: 118 AGHFAARILG 127
>UniRef50_Q11CU3 Cluster: Phosphoribosylaminoimidazole carboxylase,
catalytic subunit; n=19; Bacteria|Rep:
Phosphoribosylaminoimidazole carboxylase, catalytic
subunit - Mesorhizobium sp. (strain BNC1)
Length = 165
Score = 52.8 bits (121), Expect = 6e-06
Identities = 43/133 (32%), Positives = 64/133 (48%), Gaps = 6/133 (4%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D E + A L + D+R+ SAH+ T + L + G V IA
Sbjct: 8 VAIIMGSQSDWETMRHAADILETLEISHDVRIVSAHR-TPDRLYAFAKGAKAEGIRVIIA 66
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLV-QD-IWSSLSVPSGLGCATVIYPDS---- 556
AG + L + + TS PV P S L QD + S + +P+G+ T+ S
Sbjct: 67 GAGGAAHLPGMTAALTSLPVFGVPVQSKALSGQDSLLSIVQMPAGIPVGTLAIGRSGAVN 126
Query: 557 AALMAAQIIGLQD 595
AAL+AA ++ L D
Sbjct: 127 AALLAAAVLALSD 139
>UniRef50_Q5XEE9 Cluster: Phosphoribosylaminoimidazole carboxylase
carboxyltransferase subunit; n=18; Streptococcus|Rep:
Phosphoribosylaminoimidazole carboxylase
carboxyltransferase subunit - Streptococcus pyogenes
serotype M6
Length = 203
Score = 52.0 bits (119), Expect = 1e-05
Identities = 36/133 (27%), Positives = 67/133 (50%), Gaps = 6/133 (4%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
+ + MGS +D QK A+ G+ + +V SAH+ + + ++ G + IA
Sbjct: 46 ISIIMGSKSDWATMQKTAEILDNFGIAYEKKVVSAHRTPDLMFKHAEEARG-RGIKIIIA 104
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD----S 556
AG + L +++ T+ PVI P S L + ++S + +P G+ AT+ + +
Sbjct: 105 GAGGAAHLPGMVAAKTTLPVIGVPVKSRVLSGLDSLYSIVQMPGGVPVATMAIGEAGATN 164
Query: 557 AALMAAQIIGLQD 595
AAL A +I+ ++D
Sbjct: 165 AALTALRILSIED 177
>UniRef50_Q4AJE5 Cluster:
1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate
(AIR) carboxylase; n=2; Bacteria|Rep:
1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate
(AIR) carboxylase - Chlorobium phaeobacteroides BS1
Length = 174
Score = 52.0 bits (119), Expect = 1e-05
Identities = 42/131 (32%), Positives = 66/131 (50%), Gaps = 4/131 (3%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D + ++ A E + ++ V SAH+ T + L ++G + IA
Sbjct: 12 VGILMGSDSDFDIMKEAAAVLDEFSIPYEMSVISAHR-TPKDLEAYATQAKSNGLKIIIA 70
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLV-QD-IWSSLSVPSGLGCATVIYPD--SAA 562
AG + L V + T PVI P + KL QD ++S + +P G+ ATV + + A
Sbjct: 71 GAGAAAHLPGVTAAFTVLPVIGVPIFNKKLSGQDSLYSIVQMPPGIPVATVGIDNARNGA 130
Query: 563 LMAAQIIGLQD 595
LMA I+ L D
Sbjct: 131 LMAVHILALTD 141
>UniRef50_A0JU62 Cluster: Phosphoribosylaminoimidazole carboxylase,
catalytic subunit; n=4; cellular organisms|Rep:
Phosphoribosylaminoimidazole carboxylase, catalytic
subunit - Arthrobacter sp. (strain FB24)
Length = 196
Score = 51.6 bits (118), Expect = 1e-05
Identities = 40/127 (31%), Positives = 63/127 (49%), Gaps = 4/127 (3%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D + A+A E G+ + V SAH+ E +R Q + G V IA
Sbjct: 19 VGLVMGSDSDWPVMEAAAEALAEFGIPFEADVVSAHRMPTEMIRYGQTAHE-RGLRVIIA 77
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD--SAA 562
AG + L +L+ T PVI P P L + + S + +P+G+ ATV +A
Sbjct: 78 GAGGAAHLPGMLASVTPLPVIGVPVPLKTLDGMDSLLSIVQMPAGVPVATVSIAGARNAG 137
Query: 563 LMAAQII 583
L+A +++
Sbjct: 138 LLAVRML 144
>UniRef50_P96880 Cluster: Phosphoribosylaminoimidazole carboxylase
catalytic subunit; n=58; cellular organisms|Rep:
Phosphoribosylaminoimidazole carboxylase catalytic
subunit - Mycobacterium tuberculosis
Length = 174
Score = 51.6 bits (118), Expect = 1e-05
Identities = 40/129 (31%), Positives = 64/129 (49%), Gaps = 4/129 (3%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
+V V MGS +D A A E + ++RV SAH+ T E + + G V I
Sbjct: 9 RVGVIMGSDSDWPVMADAAAALAEFDIPAEVRVVSAHR-TPEAMFSYARGAAERGLEVII 67
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIY--PDSA 559
A AG + L +++ T PVI P P +L + + S + +P+G+ ATV +A
Sbjct: 68 AGAGGAAHLPGMVAAATPLPVIGVPVPLGRLDGLDSLLSIVQMPAGVPVATVSIGGAGNA 127
Query: 560 ALMAAQIIG 586
L+A +++G
Sbjct: 128 GLLAVRMLG 136
>UniRef50_Q6NRP1 Cluster: LOC431975 protein; n=2; Xenopus|Rep:
LOC431975 protein - Xenopus laevis (African clawed frog)
Length = 371
Score = 51.2 bits (117), Expect = 2e-05
Identities = 22/51 (43%), Positives = 34/51 (66%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYE 364
+VV+ M S +D HC++I K+ + G+ +LRV SAH +ETL I+ +YE
Sbjct: 305 RVVLLMESTSDLAHCEEIKKSCTKYGMKCELRVASAHTGPQETLDILAEYE 355
>UniRef50_P72157 Cluster: Phosphoribosylaminoimidazole carboxylase
catalytic subunit; n=126; Bacteria|Rep:
Phosphoribosylaminoimidazole carboxylase catalytic
subunit - Pseudomonas aeruginosa
Length = 163
Score = 51.2 bits (117), Expect = 2e-05
Identities = 39/130 (30%), Positives = 64/130 (49%), Gaps = 6/130 (4%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V V MGS +D A +LG+ +++V SAH+ + + ++ E G V IA
Sbjct: 5 VGVIMGSKSDWSTLSHTADMLDKLGIPYEVKVVSAHRTPDLLFQYAEEAEG-RGLEVIIA 63
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD----S 556
AG + L + + T PV+ P S L V + S + +P+G+ AT+ +
Sbjct: 64 GAGGAAHLPGMCAAKTHLPVLGVPVQSSMLSGVDSLLSIVQMPAGVPVATLAIGKAGAVN 123
Query: 557 AALMAAQIIG 586
AAL++A I+G
Sbjct: 124 AALLSASILG 133
>UniRef50_Q93J44 Cluster: Phosphoribosylaminoimidazole carboxylase
catalytic subunit PurE; n=47; cellular organisms|Rep:
Phosphoribosylaminoimidazole carboxylase catalytic
subunit PurE - Streptomyces coelicolor
Length = 180
Score = 50.8 bits (116), Expect = 2e-05
Identities = 41/131 (31%), Positives = 63/131 (48%), Gaps = 4/131 (3%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D + AKA E + ++ V SAH+ E + +Q G IA
Sbjct: 11 VGIVMGSDSDWPVMEAAAKALDEFEVPYEVDVVSAHRMPHEMIAYGEQAAG-RGLKAIIA 69
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIY--PDSAA 562
AG + L +L+ T PVI P P L + + S + +P+G+ ATV +A
Sbjct: 70 GAGGAAHLPGMLASVTPLPVIGVPVPLKYLDGMDSLLSIVQMPAGVPVATVSVGGARNAG 129
Query: 563 LMAAQIIGLQD 595
L+AA+I+ D
Sbjct: 130 LLAARILAAHD 140
>UniRef50_A1T5T8 Cluster: Phosphoribosylaminoimidazole carboxylase,
catalytic subunit; n=7; cellular organisms|Rep:
Phosphoribosylaminoimidazole carboxylase, catalytic
subunit - Mycobacterium vanbaalenii (strain DSM 7251 /
PYR-1)
Length = 166
Score = 48.8 bits (111), Expect = 1e-04
Identities = 39/132 (29%), Positives = 63/132 (47%), Gaps = 4/132 (3%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
+V + MGS +D + A+A E + ++ V SAH+ L G V I
Sbjct: 4 RVGLIMGSDSDWPVMSEAAEALAEFDVPFEVGVVSAHRTPARMLSYAADAAG-RGLEVII 62
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIY--PDSA 559
A AG + L +++ T PVI P P +L + + S + +P+G+ ATV +A
Sbjct: 63 AGAGGAAHLPGMVASATPLPVIGVPVPLARLDGLDSLLSIVQMPAGVPVATVSIGGARNA 122
Query: 560 ALMAAQIIGLQD 595
L+A +I+G D
Sbjct: 123 GLLAVRILGAAD 134
>UniRef50_Q2J4S5 Cluster: Phosphoribosylaminoimidazole carboxylase,
catalytic subunit; n=3; Frankia|Rep:
Phosphoribosylaminoimidazole carboxylase, catalytic
subunit - Frankia sp. (strain CcI3)
Length = 174
Score = 47.6 bits (108), Expect = 2e-04
Identities = 38/134 (28%), Positives = 59/134 (44%), Gaps = 4/134 (2%)
Frame = +2
Query: 206 HHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALV 385
H +V + GSP+D + K G+ + SAH+A + Q V
Sbjct: 10 HPQVAIVFGSPSDTQTMSKAGATLERFGVPYEQVSLSAHRAPRTLADYVGQLR-ARDISV 68
Query: 386 FIAVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPDS- 556
IA AG + L ++ T+ PVI P L + + + +P G+ ATV +S
Sbjct: 69 VIAGAGLAAALPGTIAALTTLPVIGVPISGGALDGMDSLLAIAQMPPGVPVATVGLNNST 128
Query: 557 -AALMAAQIIGLQD 595
AA++A QI+ L D
Sbjct: 129 NAAILAIQILALAD 142
>UniRef50_A4M8A1 Cluster:
1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate
(AIR) carboxylase; n=1; Petrotoga mobilis SJ95|Rep:
1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate
(AIR) carboxylase - Petrotoga mobilis SJ95
Length = 139
Score = 47.6 bits (108), Expect = 2e-04
Identities = 31/112 (27%), Positives = 56/112 (50%), Gaps = 2/112 (1%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
KV++ GS +D+ + E + D +V SAH+ +E + +++ ++ I
Sbjct: 4 KVLLISGSQSDEIFVKTAIDLFEEWKISYDYKVFSAHRNLKELTKFIEELPSNEYCVI-I 62
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATV 541
AVAG S L V++ T+ PV+ P L + + S + +PSG+ AT+
Sbjct: 63 AVAGLSAALPGVIASLTNLPVVGVPRDVGPLNGIDALLSMVQMPSGVPVATM 114
>UniRef50_P21264 Cluster: Phosphoribosylaminoimidazole carboxylase;
n=62; cellular organisms|Rep:
Phosphoribosylaminoimidazole carboxylase - Saccharomyces
cerevisiae (Baker's yeast)
Length = 571
Score = 47.6 bits (108), Expect = 2e-04
Identities = 40/146 (27%), Positives = 66/146 (45%), Gaps = 4/146 (2%)
Frame = +2
Query: 170 VKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRI 349
V +LD L+ + V + MGS +D ++ G+ ++ + SAH+ T +
Sbjct: 391 VAQKLD-LEAMVKPLVGIIMGSDSDLPVMSAACAVLKDFGVPFEVTIVSAHR-TPHRMSA 448
Query: 350 MQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSG 523
G IA AG + L +++ T PVI P L V + S + +P G
Sbjct: 449 YAISASKRGIKTIIAGAGGAAHLPGMVAAMTPLPVIGVPVKGSCLDGVDSLHSIVQMPRG 508
Query: 524 LGCATVIYPDS--AALMAAQIIGLQD 595
+ ATV +S AAL+A +++G D
Sbjct: 509 VPVATVAINNSTNAALLAVRLLGAYD 534
>UniRef50_Q55498 Cluster: Phosphoribosylaminoimidazole carboxylase
catalytic subunit; n=200; cellular organisms|Rep:
Phosphoribosylaminoimidazole carboxylase catalytic
subunit - Synechocystis sp. (strain PCC 6803)
Length = 176
Score = 47.6 bits (108), Expect = 2e-04
Identities = 35/127 (27%), Positives = 58/127 (45%), Gaps = 4/127 (3%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D E + ++ + SAH+ E + Q G + IA
Sbjct: 8 VGIIMGSDSDLPTMAAAIAVCEEFAVPTEVAIISAHRTPERMVEYAQTAHQ-RGLRIIIA 66
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCATVIYPD--SAA 562
AG + L +++ T PVI P + L V ++S + +P G+ ATV + +A
Sbjct: 67 GAGGAAHLPGMVAALTPLPVIGVPVQTKTLQGVDSLYSIVQMPGGIPVATVAIGNAKNAG 126
Query: 563 LMAAQII 583
L+A QI+
Sbjct: 127 LLAVQIL 133
>UniRef50_Q466M0 Cluster: Phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoribosylaminoimidazole
succinocarboxamide synthetase; n=3; Archaea|Rep:
Phosphoribosylaminoimidazole carboxylase,
phosphoribosylaminoribosylaminoimidazole
succinocarboxamide synthetase - Methanosarcina barkeri
(strain Fusaro / DSM 804)
Length = 296
Score = 46.4 bits (105), Expect = 5e-04
Identities = 22/48 (45%), Positives = 30/48 (62%)
Frame = +2
Query: 23 IVLADVIDSDSWRLWPSGDKRLMVDKQVYRNLTTVTAADLDTVKRNFA 166
IV+ADVID+DSWR+W G+ +DKQ +R+ LD V N+A
Sbjct: 245 IVIADVIDNDSWRIWSGGNPEKQLDKQCFRD-----GNPLDQVAENYA 287
>UniRef50_P15567 Cluster: Phosphoribosylaminoimidazole carboxylase;
n=53; cellular organisms|Rep:
Phosphoribosylaminoimidazole carboxylase -
Schizosaccharomyces pombe (Fission yeast)
Length = 552
Score = 46.4 bits (105), Expect = 5e-04
Identities = 39/138 (28%), Positives = 63/138 (45%), Gaps = 4/138 (2%)
Frame = +2
Query: 182 LDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQY 361
LD P V + MGS +D + A E + +L + SAH+ T + + +
Sbjct: 377 LDVKDPVESPVVGIIMGSDSDLSKMKDAAVILDEFKVPYELTIVSAHR-TPDRMVTYART 435
Query: 362 EDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCPPPSDKL--VQDIWSSLSVPSGLGCA 535
+ G V IA AG + L +++ T PVI P L V + S + +P G+ A
Sbjct: 436 AASRGLRVIIAGAGGAAHLPGMVAAMTPLPVIGVPVKGSTLDGVDSLHSIVQMPRGVPVA 495
Query: 536 TVIYPDS--AALMAAQII 583
TV +S A ++A +I+
Sbjct: 496 TVAINNSQNAGILACRIL 513
>UniRef50_A7D0F6 Cluster: NCAIR mutase (PurE)-related protein; n=1;
Halorubrum lacusprofundi ATCC 49239|Rep: NCAIR mutase
(PurE)-related protein - Halorubrum lacusprofundi ATCC
49239
Length = 260
Score = 44.0 bits (99), Expect = 0.003
Identities = 34/112 (30%), Positives = 51/112 (45%)
Frame = +2
Query: 131 AADLDTVKRNFAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRV 310
+A +D +R V DF +P ++ V V AD + A ARE+G +D R+
Sbjct: 99 SAAVDHDERTGTVVVHADDFERPDLNATVAVVAAGTADAAVAGEAAVVAREIGATID-RI 157
Query: 311 TSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCP 466
A + RI+ Q + A V + AGR L V++G + PVI P
Sbjct: 158 DDVGVANLD--RILDQRDRIREADVVVVAAGREGALPTVVAGLVAAPVIALP 207
>UniRef50_Q98FE6 Cluster: Phosphoribosylaminoimidazole carboxylase
I; n=5; Proteobacteria|Rep: Phosphoribosylaminoimidazole
carboxylase I - Rhizobium loti (Mesorhizobium loti)
Length = 165
Score = 43.2 bits (97), Expect = 0.005
Identities = 39/133 (29%), Positives = 62/133 (46%), Gaps = 6/133 (4%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D ++ A+ LG+ + SAH+ T + L + G V IA
Sbjct: 8 VAIIMGSQSDWATMRQAAETLEALGVPHKRLIISAHR-TPDRLYEFAKGAKAAGYKVIIA 66
Query: 395 VAGRSNGLGPVLSGNTSYPVINCPPPSDKLV-QD-IWSSLSVPSGLGCATVIY----PDS 556
AG + L + + T PV P S L QD + S + +P+G+ T+ +
Sbjct: 67 GAGGAAHLPGMTAAMTPLPVFGVPVESKALSGQDSLLSIVQMPAGIPVGTLAIGKAGAAN 126
Query: 557 AALMAAQIIGLQD 595
AAL+AA ++ L D
Sbjct: 127 AALLAAAVLALND 139
>UniRef50_Q5FIU8 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamidesynthase;
n=6; Lactobacillus|Rep:
Phosphoribosylaminoimidazole-succinocarboxamidesynthase
- Lactobacillus acidophilus
Length = 238
Score = 40.3 bits (90), Expect = 0.034
Identities = 24/55 (43%), Positives = 31/55 (56%), Gaps = 4/55 (7%)
Frame = +2
Query: 2 GVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYR----NLTTVTAADLDTVK 154
G D +G+I+LAD D+ RLW K M DK VYR +LTTV DL ++
Sbjct: 179 GKDADGNIILADEFSPDNCRLWDKKTKEHM-DKDVYRRDIGDLTTVYEQDLARIQ 232
>UniRef50_Q6BIQ2 Cluster: Similar to CA4826|IPF1206 Candida albicans
IPF1206 unknown function; n=1; Debaryomyces
hansenii|Rep: Similar to CA4826|IPF1206 Candida albicans
IPF1206 unknown function - Debaryomyces hansenii (Yeast)
(Torulaspora hansenii)
Length = 556
Score = 37.9 bits (84), Expect = 0.18
Identities = 44/161 (27%), Positives = 66/161 (40%), Gaps = 1/161 (0%)
Frame = +2
Query: 74 GDKRLMVDKQVYRNLTTVTAADLDTVKRNFAWVKDQLDFLKPTIHHKVVVFMGSPADQEH 253
G+K+ +VY ++ TV A+ + K A KD F K T + + +
Sbjct: 71 GNKQYSTFYEVYHDIKTVAASRIQKYKVGSAKYKDIDFFYKFTTE----LLLRESSRLNL 126
Query: 254 CQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALV-FIAVAGRSNGLGPVL 430
AK E DV + TE+ +I Y T+G +V FI + + P L
Sbjct: 127 AVFHAKKGNE---DVVGPSELETQLTEDFNKISVSYNLTNGEVVTFIYKSEEPSSSMPPL 183
Query: 431 SGNTSYPVINCPPPSDKLVQDIWSSLSVPSGLGCATVIYPD 553
P PPP K+ Q ++SSL+ S L + I PD
Sbjct: 184 PNAYHSPYPQPPPPPQKIKQPLFSSLTGKSNLDPRSTIVPD 224
>UniRef50_P12046 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=61; Bacilli|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Bacillus subtilis
Length = 241
Score = 36.3 bits (80), Expect = 0.56
Identities = 19/46 (41%), Positives = 29/46 (63%), Gaps = 1/46 (2%)
Frame = +2
Query: 2 GVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVY-RNLTTVTAA 136
G+D EG ++LAD I D+ RLW + +DK ++ RNL ++T A
Sbjct: 183 GLDAEGQVLLADEISPDTCRLWDK-ETNEKLDKDLFRRNLGSLTDA 227
>UniRef50_A6CXW5 Cluster: Putative uncharacterized protein; n=1;
Vibrio shilonii AK1|Rep: Putative uncharacterized
protein - Vibrio shilonii AK1
Length = 220
Score = 35.5 bits (78), Expect = 0.97
Identities = 24/84 (28%), Positives = 35/84 (41%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
+ + G +D C +I + G+ L A R+ ED + A + IA
Sbjct: 89 IAIVSGGSSDTNICHEILRTLNYHGVSASLYEDVGVSAL---WRLTNALEDINKAKIIIA 145
Query: 395 VAGRSNGLGPVLSGNTSYPVINCP 466
VAG L VL+G T P+I P
Sbjct: 146 VAGMEAALPTVLAGLTPRPIIAVP 169
>UniRef50_O57978 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=6; cellular organisms|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Pyrococcus horikoshii
Length = 238
Score = 35.5 bits (78), Expect = 0.97
Identities = 18/37 (48%), Positives = 22/37 (59%)
Frame = +2
Query: 2 GVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYR 112
G D G IVLAD I D+ R W + KR +DK V+R
Sbjct: 179 GKDKNGDIVLADEISPDTCRFWDAKTKR-SLDKDVFR 214
>UniRef50_A4G5F2 Cluster: Universal stress protein; n=4;
Herminiimonas arsenicoxydans|Rep: Universal stress
protein - Herminiimonas arsenicoxydans
Length = 143
Score = 35.1 bits (77), Expect = 1.3
Identities = 21/71 (29%), Positives = 37/71 (52%)
Frame = +2
Query: 245 QEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGLGP 424
+++ KIA A LG+D ++ V A++E ++ +Y H +F+A GR GL
Sbjct: 66 EKYVHKIATHAASLGVDAEVHVVEGTSASDEIIKAADKY---HCDAIFMASHGR-KGLDK 121
Query: 425 VLSGNTSYPVI 457
L G+ + V+
Sbjct: 122 FLLGSEAQKVL 132
>UniRef50_A3S2A4 Cluster: ATP-dependent exoDNAse alpha subunit; n=1;
Prochlorococcus marinus str. MIT 9211|Rep: ATP-dependent
exoDNAse alpha subunit - Prochlorococcus marinus str.
MIT 9211
Length = 574
Score = 35.1 bits (77), Expect = 1.3
Identities = 21/105 (20%), Positives = 42/105 (40%)
Frame = +2
Query: 56 WRLWPSGDKRLMVDKQVYRNLTTVTAADLDTVKRNFAWVKDQLDFLKPTIHHKVVVFMGS 235
W G + ++ K R + D D +K +QL L+ H +V+ G
Sbjct: 101 WDYEMKGIIKDLIKKSNQRPKLAIIEVDKDAIKSTVKLNSEQLLALESITSHNLVLLSGG 160
Query: 236 PADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDT 370
P + + + L +D++LR+ A + T R+ + + +
Sbjct: 161 PGTGKTSTIVEMLRKSLSIDLELRIGLAAPTGKATRRLQESLQSS 205
>UniRef50_Q9YBE5 Cluster: PqqE homolog; n=4; Thermoprotei|Rep: PqqE
homolog - Aeropyrum pernix
Length = 389
Score = 35.1 bits (77), Expect = 1.3
Identities = 27/84 (32%), Positives = 42/84 (50%)
Frame = +2
Query: 116 LTTVTAADLDTVKRNFAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLD 295
+T TAA L + F++V LD + P +H K F G+P + + A+ A E GLD
Sbjct: 122 ITRETAARLRRL--GFSYVGISLDSVDPGVHDK---FRGAPGAFKAAIRGARNALEEGLD 176
Query: 296 VDLRVTSAHKATEETLRIMQQYED 367
V R+T ++ RI++ D
Sbjct: 177 VGFRLTITKYNLDDAPRIIRLASD 200
>UniRef50_O28993 Cluster: Putative uncharacterized protein; n=1;
Archaeoglobus fulgidus|Rep: Putative uncharacterized
protein - Archaeoglobus fulgidus
Length = 229
Score = 35.1 bits (77), Expect = 1.3
Identities = 27/89 (30%), Positives = 39/89 (43%), Gaps = 4/89 (4%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDV----DLRVTSAHKATEETLRIMQQYEDTHGA 379
KV + +D ++ A A LGL+V D+ V H+ E RI ++ D+
Sbjct: 91 KVAILTAGTSDIPVAEEAAVTAEFLGLEVLRFYDVGVAGLHRIVEPVKRIREENVDSA-- 148
Query: 380 LVFIAVAGRSNGLGPVLSGNTSYPVINCP 466
I VAG L V++G PVI P
Sbjct: 149 ---IVVAGMEGALPSVIAGLVDVPVIAVP 174
>UniRef50_Q8AAD6 Cluster: Indole-3-glycerol phosphate synthase; n=7;
Bacteroidales|Rep: Indole-3-glycerol phosphate synthase
- Bacteroides thetaiotaomicron
Length = 260
Score = 35.1 bits (77), Expect = 1.3
Identities = 19/63 (30%), Positives = 36/63 (57%)
Frame = +2
Query: 137 DLDTVKRNFAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTS 316
D+ ++++F + QL + + V+ + + QE CQ++A+ A ELGL+V L + S
Sbjct: 111 DVPIIRKDFIIDEYQL-YQAKIVGADAVLLIAAALKQEKCQELAEQAHELGLEVLLEIHS 169
Query: 317 AHK 325
A +
Sbjct: 170 AEE 172
>UniRef50_Q58987 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=5; Euryarchaeota|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Methanococcus jannaschii
Length = 242
Score = 35.1 bits (77), Expect = 1.3
Identities = 16/37 (43%), Positives = 25/37 (67%)
Frame = +2
Query: 2 GVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYR 112
G D EG++++AD I D+ RLW + R ++DK V+R
Sbjct: 187 GKDREGNLLVADEISPDTMRLWDK-ETRDVLDKDVFR 222
>UniRef50_A7H038 Cluster: Ncair mutase; n=8; Bacteria|Rep: Ncair
mutase - Campylobacter curvus 525.92
Length = 248
Score = 34.7 bits (76), Expect = 1.7
Identities = 24/84 (28%), Positives = 38/84 (45%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
+ + +D ++ + A+ LG V ++T A R+ + +D GA V IA
Sbjct: 121 IAIISAGTSDMSVVEEAYETAKFLGNSVK-KITDVGVAGIH--RLFSKLDDIQGARVVIA 177
Query: 395 VAGRSNGLGPVLSGNTSYPVINCP 466
VAG L V++G PVI P
Sbjct: 178 VAGMEGALPSVIAGLVKAPVIAVP 201
>UniRef50_A4BQ22 Cluster: Putative uncharacterized protein; n=1;
Nitrococcus mobilis Nb-231|Rep: Putative uncharacterized
protein - Nitrococcus mobilis Nb-231
Length = 339
Score = 34.7 bits (76), Expect = 1.7
Identities = 23/82 (28%), Positives = 42/82 (51%), Gaps = 3/82 (3%)
Frame = +2
Query: 80 KRLMVDKQVYRNLTTVTAADLDTVKRNFAWV---KDQLDFLKPTIHHKVVVFMGSPADQE 250
+R MVD + R L+ ++A ++ ++ + +W+ DQ+ LK +H+ + + A
Sbjct: 13 QRRMVDS-LQRTLSQGSSAPVEVMETHLSWLLLSADQVIKLKKALHYSYLDYSTVEARYR 71
Query: 251 HCQKIAKAARELGLDVDLRVTS 316
CQ + R L DV L V+S
Sbjct: 72 QCQTEVRLNRRLAPDVYLAVSS 93
>UniRef50_Q92AN6 Cluster:
Phosphoribosylaminoimidazole-succinocarboxamide
synthase; n=17; Bacteria|Rep:
Phosphoribosylaminoimidazole-succinocarboxamide synthase
- Listeria innocua
Length = 237
Score = 34.7 bits (76), Expect = 1.7
Identities = 22/56 (39%), Positives = 31/56 (55%), Gaps = 4/56 (7%)
Frame = +2
Query: 2 GVDTEGSIVLADVIDSDSWRLWPSGDKRLMVDKQVYR----NLTTVTAADLDTVKR 157
G D G+I+LAD I D+ RLW + +DK V+R NLT V L+ +K+
Sbjct: 180 GRDAAGNILLADEISPDTCRLWDK-ETNQKLDKDVFRRNIGNLTDVYTEVLNRLKQ 234
>UniRef50_Q18IR2 Cluster: NCAIR mutase (PurE)-related protein; n=2;
Halobacteriaceae|Rep: NCAIR mutase (PurE)-related
protein - Haloquadratum walsbyi (strain DSM 16790)
Length = 249
Score = 34.3 bits (75), Expect = 2.3
Identities = 29/113 (25%), Positives = 44/113 (38%)
Frame = +2
Query: 128 TAADLDTVKRNFAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLR 307
TAA +R+ +V DF +P V V +D ++ + E+G V+
Sbjct: 95 TAATTQFYERSRTFVGHASDFERPDHDGTVGVVTAGTSDITVAEQAVALSEEMGCAVE-- 152
Query: 308 VTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCP 466
T R++ + E I AGR L V++G S PVI P
Sbjct: 153 -TLYDVGVSGIHRLLSERETLADCDCVIVAAGREGALATVVAGMVSAPVIGLP 204
>UniRef50_Q2SGQ5 Cluster: Glycosyltransferase; n=1; Hahella
chejuensis KCTC 2396|Rep: Glycosyltransferase - Hahella
chejuensis (strain KCTC 2396)
Length = 419
Score = 33.9 bits (74), Expect = 3.0
Identities = 23/91 (25%), Positives = 44/91 (48%)
Frame = +2
Query: 92 VDKQVYRNLTTVTAADLDTVKRNFAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAK 271
VD ++ + LD V RN + + L+ + + VV +G DQ+H + +
Sbjct: 214 VDNRMRGRRALIYLGSLDYV-RNIETLFEMASLLRWRLPNIVVAIVGDTNDQQHKTWLQE 272
Query: 272 AARELGLDVDLRVTSAHKATEETLRIMQQYE 364
AR+LG+D D+ + + +E R +++ E
Sbjct: 273 RARQLGVD-DILIWTGWLPMQEAWRYIREAE 302
>UniRef50_UPI0000DB74A8 Cluster: PREDICTED: similar to CG5199-PA;
n=1; Apis mellifera|Rep: PREDICTED: similar to CG5199-PA
- Apis mellifera
Length = 344
Score = 33.5 bits (73), Expect = 3.9
Identities = 18/38 (47%), Positives = 24/38 (63%)
Frame = +2
Query: 47 SDSWRLWPSGDKRLMVDKQVYRNLTTVTAADLDTVKRN 160
S+SW PS D+ L++ K+ R T V + DLDT KRN
Sbjct: 57 SESWSPAPSPDE-LVIQKRGRRRRTIVWSPDLDTCKRN 93
>UniRef50_Q8RJP6 Cluster: Putative uncharacterized protein; n=11;
Xanthomonas|Rep: Putative uncharacterized protein -
Xanthomonas euvesicatoria
Length = 339
Score = 33.5 bits (73), Expect = 3.9
Identities = 30/110 (27%), Positives = 50/110 (45%), Gaps = 3/110 (2%)
Frame = +2
Query: 272 AARELGLDVDLR-VTSAHKATEETLRIMQQYEDTHGALV--FIAVAGRSNGLGPVLSGNT 442
AAR L ++ + +A A + T R++ T+G + + AGR G+ VL+
Sbjct: 123 AARLLASELKVAPYAAARDAIQATFRMVGMRSPTNGGVSDPHVTSAGRFYGMANVLTNLA 182
Query: 443 SYPVINCPPPSDKLVQDIWSSLSVPSGLGCATVIYPDSAALMAAQIIGLQ 592
S + P + W+ L P +G AT + AA+ AA +GL+
Sbjct: 183 SNEL---EAPDFASARQRWAGLMSPFNMGEATRVVFQQAAVNAALNVGLE 229
>UniRef50_Q2ADF8 Cluster: Adenylyl cyclase class-3/4/guanylyl
cyclase:CHASE2 precursor; n=1; Halothermothrix orenii H
168|Rep: Adenylyl cyclase class-3/4/guanylyl
cyclase:CHASE2 precursor - Halothermothrix orenii H 168
Length = 582
Score = 33.5 bits (73), Expect = 3.9
Identities = 17/48 (35%), Positives = 28/48 (58%)
Frame = +2
Query: 275 ARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGL 418
AR +GLD+ L +S +A E+ ++++ QYE+ L +A G GL
Sbjct: 92 ARAIGLDIILEASSGREADEKLVKVLSQYENV--VLPAVARVGLVRGL 137
>UniRef50_Q7K274 Cluster: LD15586p; n=6; Diptera|Rep: LD15586p -
Drosophila melanogaster (Fruit fly)
Length = 389
Score = 33.5 bits (73), Expect = 3.9
Identities = 22/77 (28%), Positives = 37/77 (48%)
Frame = +2
Query: 68 PSGDKRLMVDKQVYRNLTTVTAADLDTVKRNFAWVKDQLDFLKPTIHHKVVVFMGSPADQ 247
PS ++R + + + +N+T T+ K L F KPT + V++ A Q
Sbjct: 104 PSNNRRYLSSQDITKNMTLYTST-----KTQVEVDPKTLAFKKPTGNPLVLMMAWLMAKQ 158
Query: 248 EHCQKIAKAARELGLDV 298
+H +K A+ E+G DV
Sbjct: 159 KHLKKYAQIYTEMGFDV 175
>UniRef50_P73194 Cluster: Slr1699 protein; n=1; Synechocystis sp.
PCC 6803|Rep: Slr1699 protein - Synechocystis sp.
(strain PCC 6803)
Length = 282
Score = 33.1 bits (72), Expect = 5.2
Identities = 26/87 (29%), Positives = 38/87 (43%), Gaps = 6/87 (6%)
Frame = +2
Query: 263 IAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAV--AGRSNGLGPVLSG 436
+ K R+L L VDL E L I + Y L+ + ++ GL P+L+
Sbjct: 151 VQKQLRQLNLQVDLNFEFTPSPEETNLLIAENYRVRRNLLIKFSNDDIDQTLGLRPILNQ 210
Query: 437 NTSYPVINCPPPSDKLV---QDI-WSS 505
T+ V CP P + L QDI W +
Sbjct: 211 QTADLVAYCPLPGNHLTPLGQDIQWET 237
>UniRef50_A0RWQ1 Cluster: Phosphoribosylcarboxyaminoimidazole
(NCAIR) mutase; n=1; Cenarchaeum symbiosum|Rep:
Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase -
Cenarchaeum symbiosum
Length = 181
Score = 33.1 bits (72), Expect = 5.2
Identities = 24/85 (28%), Positives = 41/85 (48%)
Frame = +2
Query: 212 KVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFI 391
+V + MGS +D + A+ G+ + + SAH+ T E L ++ + G V I
Sbjct: 8 EVGIIMGSSSDARIMLEAARVLDGFGVLHEDLIVSAHR-TPERLGDYARHAEEIGLRVII 66
Query: 392 AVAGRSNGLGPVLSGNTSYPVINCP 466
A AG + L +++ T PV+ P
Sbjct: 67 AGAGGAAHLPGMIASYTVVPVVGVP 91
>UniRef50_Q89GN0 Cluster: Blr6315 protein; n=1; Bradyrhizobium
japonicum|Rep: Blr6315 protein - Bradyrhizobium
japonicum
Length = 790
Score = 32.7 bits (71), Expect = 6.9
Identities = 15/41 (36%), Positives = 25/41 (60%)
Frame = +2
Query: 242 DQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYE 364
++E +++A+ + G D+D + A KA+EE LRI Q E
Sbjct: 563 ERERAEQLARDLAKAGRDLDAQTERASKASEEVLRIKQAGE 603
>UniRef50_Q87WE4 Cluster: Putative uncharacterized protein; n=1;
Pseudomonas syringae pv. tomato|Rep: Putative
uncharacterized protein - Pseudomonas syringae pv.
tomato
Length = 819
Score = 32.7 bits (71), Expect = 6.9
Identities = 21/74 (28%), Positives = 38/74 (51%), Gaps = 3/74 (4%)
Frame = +2
Query: 278 RELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIAVAGRSNGLGP---VLSGNTSY 448
+++ L +D + + +ET I Q++ T LVF+A+ + L LSG +
Sbjct: 430 KQIILVLDNADQRSFEVQQETFLIAQEFASTRNLLVFVALRPSTFFLSKTTGALSGYQNK 489
Query: 449 PVINCPPPSDKLVQ 490
+ PPP+D++VQ
Sbjct: 490 VLTISPPPADEVVQ 503
>UniRef50_A4IPG9 Cluster: NCAIR mutase (Pure)-related protein; n=9;
Bacteria|Rep: NCAIR mutase (Pure)-related protein -
Geobacillus thermodenitrificans (strain NG80-2)
Length = 269
Score = 32.7 bits (71), Expect = 6.9
Identities = 28/102 (27%), Positives = 41/102 (40%)
Frame = +2
Query: 161 FAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEET 340
F W+ D+++ H + V +D ++ A A LG V R+ A
Sbjct: 110 FYWISQ--DYVETKKHGYIAVVSAGTSDVPIAEEAAVTAELLGCKVK-RIYDVGVAGIH- 165
Query: 341 LRIMQQYEDTHGALVFIAVAGRSNGLGPVLSGNTSYPVINCP 466
R++ E + V I VAG L V+ G S PVI P
Sbjct: 166 -RLLDNIEMIERSSVVIVVAGMEGALASVVGGLVSKPVIAVP 206
>UniRef50_Q9VIK2 Cluster: CG9317-PA, isoform A; n=7;
Endopterygota|Rep: CG9317-PA, isoform A - Drosophila
melanogaster (Fruit fly)
Length = 674
Score = 32.7 bits (71), Expect = 6.9
Identities = 14/38 (36%), Positives = 20/38 (52%)
Frame = +2
Query: 437 NTSYPVINCPPPSDKLVQDIWSSLSVPSGLGCATVIYP 550
N S+P+I CP + +WSS+ + L C IYP
Sbjct: 141 NASWPLIKCPQGWEYNTSVVWSSIVIDFDLVCDQDIYP 178
>UniRef50_A7DMC3 Cluster: Phosphoribosylaminoimidazole carboxylase,
catalytic subunit; n=1; Candidatus Nitrosopumilus
maritimus SCM1|Rep: Phosphoribosylaminoimidazole
carboxylase, catalytic subunit - Candidatus
Nitrosopumilus maritimus SCM1
Length = 191
Score = 32.7 bits (71), Expect = 6.9
Identities = 23/84 (27%), Positives = 41/84 (48%)
Frame = +2
Query: 215 VVVFMGSPADQEHCQKIAKAARELGLDVDLRVTSAHKATEETLRIMQQYEDTHGALVFIA 394
V + MGS +D + A+ + + + ++ SAH+ T L Q+ + G + IA
Sbjct: 9 VGIIMGSSSDSRIMKGAAEILDDFKVKHEDQIISAHR-TPARLAEYAQHAEKMGFDIIIA 67
Query: 395 VAGRSNGLGPVLSGNTSYPVINCP 466
AG + L +++ +T PVI P
Sbjct: 68 GAGGAAHLPGMIASHTVIPVIGVP 91
>UniRef50_Q6FPI5 Cluster: Putative guanine nucleotide-exchange factor
SED4; n=1; Candida glabrata|Rep: Putative guanine
nucleotide-exchange factor SED4 - Candida glabrata
(Yeast) (Torulopsis glabrata)
Length = 1029
Score = 32.7 bits (71), Expect = 6.9
Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 2/62 (3%)
Frame = +2
Query: 8 DTEGSIVLADVIDSDSWR-LWPSGDKRLMVDKQVYRNLT-TVTAADLDTVKRNFAWVKDQ 181
+TEG+IV A ++DS S + + + D+Q +N T +V AA +D ++ ++ V D
Sbjct: 848 NTEGTIVNASLVDSQSSNSSVKTVETNVSQDEQTSQNETLSVGAATIDVIQGSYTSVSDS 907
Query: 182 LD 187
LD
Sbjct: 908 LD 909
>UniRef50_A7AVF9 Cluster: Translation factor Sua5, putative; n=1;
Babesia bovis|Rep: Translation factor Sua5, putative -
Babesia bovis
Length = 453
Score = 32.3 bits (70), Expect = 9.1
Identities = 17/46 (36%), Positives = 26/46 (56%), Gaps = 2/46 (4%)
Frame = +2
Query: 389 IAVAGRSNGLGPVLSGNTSYPVINCP--PPSDKLVQDIWSSLSVPS 520
I GRS G+ V+S N+ YP + CP P + +++ I L+ PS
Sbjct: 113 IITRGRS-GIPRVVSANSGYPAVRCPNHPDAQAILKHIGFPLAAPS 157
>UniRef50_Q2GSZ3 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized protein
- Chaetomium globosum (Soil fungus)
Length = 1172
Score = 32.3 bits (70), Expect = 9.1
Identities = 21/82 (25%), Positives = 37/82 (45%)
Frame = +2
Query: 131 AADLDTVKRNFAWVKDQLDFLKPTIHHKVVVFMGSPADQEHCQKIAKAARELGLDVDLRV 310
AA L+ +K+ K D K T + + + +H +++AK ELG +++
Sbjct: 766 AALLEQIKQELE-AKHAEDLAKVTAQLEAASDLKEELEAKHAEEVAKLTAELGSASEVKE 824
Query: 311 TSAHKATEETLRIMQQYEDTHG 376
K +EE ++M Q E G
Sbjct: 825 ALEAKHSEEVEKLMAQLEAASG 846
>UniRef50_Q0UH42 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 930
Score = 32.3 bits (70), Expect = 9.1
Identities = 13/42 (30%), Positives = 21/42 (50%)
Frame = -3
Query: 222 TTTLWWIVGFKKSSWSFTQAKLRLTVSRSAAVTVVRFRYTCL 97
TTT+W + SWSF + R+ + V ++RF C+
Sbjct: 347 TTTIWGLAYMATFSWSFVKLTSRIADPNQSPVGILRFPTVCI 388
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 673,543,492
Number of Sequences: 1657284
Number of extensions: 14908542
Number of successful extensions: 37796
Number of sequences better than 10.0: 69
Number of HSP's better than 10.0 without gapping: 36464
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 37766
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 42732687689
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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