Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV1d02f
(616 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component sub... 160 3e-38
UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alph... 138 7e-32
UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component sub... 135 7e-31
UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-... 128 1e-28
UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 122 9e-27
UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component sub... 118 1e-25
UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component sub... 114 2e-24
UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alp... 109 7e-23
UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alp... 106 4e-22
UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamid... 104 2e-21
UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component sub... 103 3e-21
UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 102 6e-21
UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alp... 100 2e-20
UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=... 99 1e-19
UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutacea... 89 8e-17
UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component sub... 84 3e-15
UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whol... 83 4e-15
UniRef50_Q8TA29 Cluster: Putative pyruvate dehydrogenase; n=1; H... 83 7e-15
UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 80 5e-14
UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 79 8e-14
UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflex... 79 1e-13
UniRef50_Q42066 Cluster: Pyruvate dehydrogenase E1 componen; n=5... 76 6e-13
UniRef50_A5UVY9 Cluster: Pyruvate dehydrogenase; n=2; Roseiflexu... 76 8e-13
UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3; Prote... 75 2e-12
UniRef50_Q1NYU1 Cluster: Pyruvate dehydrogenase E1 component alp... 75 2e-12
UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 75 2e-12
UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 74 3e-12
UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidotherm... 74 3e-12
UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component sub... 73 4e-12
UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1 ... 73 7e-12
UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 71 2e-11
UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|R... 70 5e-11
UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1; R... 69 7e-11
UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 al... 69 7e-11
UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, al... 66 5e-10
UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1; Acido... 66 8e-10
UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomon... 65 1e-09
UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, al... 64 2e-09
UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, ... 64 3e-09
UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacte... 64 3e-09
UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto... 62 8e-09
UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase; ... 62 1e-08
UniRef50_Q4QC52 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 62 1e-08
UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol ox... 62 1e-08
UniRef50_Q9KG99 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 61 2e-08
UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, al... 61 2e-08
UniRef50_Q8ZUR8 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 61 2e-08
UniRef50_Q9LPL5 Cluster: Branched-chain alpha keto-acid dehydrog... 60 4e-08
UniRef50_P47516 Cluster: Pyruvate dehydrogenase E1 component sub... 60 4e-08
UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 60 5e-08
UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 60 5e-08
UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 60 5e-08
UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase (Lipoam... 59 7e-08
UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid dehydrog... 59 7e-08
UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|R... 59 7e-08
UniRef50_Q4DB65 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 59 9e-08
UniRef50_Q0W151 Cluster: Pyruvate dehydrogenase complex E1, tran... 58 1e-07
UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent dehydr... 58 2e-07
UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 58 2e-07
UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 57 3e-07
UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1; Chlor... 57 3e-07
UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3; Bac... 56 7e-07
UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,... 56 9e-07
UniRef50_A6W004 Cluster: Transketolase domain protein; n=6; Prot... 56 9e-07
UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37; Bacteria|... 55 1e-06
UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 55 1e-06
UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4; Actinomyce... 55 2e-06
UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 55 2e-06
UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E... 55 2e-06
UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit (... 55 2e-06
UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1; Solib... 54 2e-06
UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component sub... 54 2e-06
UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1 compo... 54 4e-06
UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 54 4e-06
UniRef50_Q2JA37 Cluster: Pyruvate dehydrogenase; n=11; Actinomyc... 54 4e-06
UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, al... 53 5e-06
UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit... 53 5e-06
UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1; Syntrophob... 53 6e-06
UniRef50_Q3E8Q6 Cluster: Uncharacterized protein At5g34780.1; n=... 53 6e-06
UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alp... 52 8e-06
UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridiu... 52 8e-06
UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 52 1e-05
UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8; Chla... 52 1e-05
UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC ... 51 3e-05
UniRef50_A7K3C9 Cluster: Dehydrogenase E1 component superfamily;... 51 3e-05
UniRef50_Q749T8 Cluster: Pyruvate dehydrogenase complex E1 compo... 50 3e-05
UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha su... 50 3e-05
UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4; ... 50 4e-05
UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 50 4e-05
UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALP... 50 6e-05
UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3; Bacte... 49 8e-05
UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa ... 49 8e-05
UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component sub... 49 8e-05
UniRef50_Q9VHB8 Cluster: CG8199-PA; n=2; Eukaryota|Rep: CG8199-P... 49 1e-04
UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component sub... 48 1e-04
UniRef50_Q5KUY4 Cluster: Pyruvate dehydrogenase E1 (Lipoamide) a... 48 2e-04
UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent) a... 48 2e-04
UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=... 48 2e-04
UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component sub... 47 3e-04
UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter viola... 47 3e-04
UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid decarbox... 47 3e-04
UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid dehydrog... 46 0.001
UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 46 0.001
UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, al... 46 0.001
UniRef50_A0DAM1 Cluster: Chromosome undetermined scaffold_43, wh... 46 0.001
UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 45 0.001
UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate... 45 0.002
UniRef50_A5IXN2 Cluster: Pyruvate dehydrogenase E1 component, al... 45 0.002
UniRef50_Q295J7 Cluster: GA20891-PA; n=7; Coelomata|Rep: GA20891... 44 0.002
UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid dehydrog... 44 0.002
UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alp... 44 0.003
UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alp... 44 0.004
UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp... 44 0.004
UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 43 0.005
UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3; Actinomyce... 43 0.005
UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta sub... 43 0.005
UniRef50_A0JY23 Cluster: Pyruvate dehydrogenase; n=2; Arthrobact... 43 0.005
UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, al... 43 0.005
UniRef50_Q9HNV6 Cluster: Pyruvate dehydrogenase alpha subunit; n... 43 0.005
UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1; Prochloroc... 43 0.007
UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2; Alphap... 43 0.007
UniRef50_A1UJ85 Cluster: Pyruvate dehydrogenase; n=16; Mycobacte... 43 0.007
UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 43 0.007
UniRef50_A3TUC4 Cluster: TPP-dependent acetoin dehydrogenase com... 42 0.009
UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1 compo... 42 0.009
UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component bet... 42 0.009
UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA SUB... 42 0.012
UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha... 42 0.012
UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1; Novos... 42 0.012
UniRef50_P09060 Cluster: 2-oxoisovalerate dehydrogenase subunit ... 42 0.015
UniRef50_Q1IY28 Cluster: Pyruvate dehydrogenase; n=1; Deinococcu... 41 0.020
UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway sig... 41 0.020
UniRef50_Q4P2J0 Cluster: Putative uncharacterized protein; n=1; ... 41 0.020
UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter... 40 0.036
UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4; Actinobact... 40 0.036
UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 40 0.036
UniRef50_Q8D6Q7 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 40 0.047
UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2; Bacte... 40 0.047
UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n... 40 0.047
UniRef50_Q8PQ82 Cluster: Pyruvate dehydrogenase E1 alpha subunit... 40 0.062
UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alp... 40 0.062
UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=... 40 0.062
UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3; Prote... 40 0.062
UniRef50_Q6L1L8 Cluster: Pyruvate dehydrogenase E1 component alp... 40 0.062
UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2; Rhodo... 39 0.082
UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1 compon... 39 0.082
UniRef50_Q4N1L6 Cluster: Branched-chain alpha keto-acid dehydrog... 39 0.082
UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep: ... 39 0.082
UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4; Myco... 39 0.11
UniRef50_O17231 Cluster: Putative uncharacterized protein; n=1; ... 39 0.11
UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n... 38 0.19
UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha subu... 38 0.19
UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family prot... 38 0.19
UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase alpha-s... 38 0.19
UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomon... 38 0.19
UniRef50_Q07075 Cluster: Glutamyl aminopeptidase; n=30; Euteleos... 38 0.25
UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase... 37 0.33
UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12; Bacteria|... 37 0.33
UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8; Bacter... 37 0.44
UniRef50_Q6CLM5 Cluster: DNA polymerase epsilon subunit C; n=1; ... 37 0.44
UniRef50_A7PGG3 Cluster: Chromosome chr17 scaffold_16, whole gen... 36 0.77
UniRef50_Q4SZR6 Cluster: Chromosome undetermined SCAF11537, whol... 36 1.0
UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22; Prot... 36 1.0
UniRef50_Q6FXJ5 Cluster: Similar to sp|P12351 Saccharomyces cere... 36 1.0
UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 36 1.0
UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 35 1.3
UniRef50_Q3W7K0 Cluster: Cytochrome P450; n=5; Frankia sp. EAN1p... 35 1.3
UniRef50_A4XKW2 Cluster: Putative uncharacterized protein; n=1; ... 35 1.3
UniRef50_Q98RS9 Cluster: Putative uncharacterized protein orf665... 35 1.8
UniRef50_Q23GD0 Cluster: Putative uncharacterized protein; n=1; ... 35 1.8
UniRef50_Q8Y8C3 Cluster: Lmo0985 protein; n=11; Listeria monocyt... 34 2.3
UniRef50_A6DD58 Cluster: Transcription-repair coupling factor; n... 34 2.3
UniRef50_P38147 Cluster: Serine/threonine-protein kinase CHK1; n... 34 2.3
UniRef50_UPI00015C4945 Cluster: hypothetical protein CCC13826_09... 34 3.1
UniRef50_UPI0000D56C7C Cluster: PREDICTED: similar to CG14039-PE... 34 3.1
UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Re... 34 3.1
UniRef50_Q2H9L8 Cluster: Putative uncharacterized protein; n=2; ... 34 3.1
UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 compone... 34 3.1
UniRef50_UPI0000F2B7FC Cluster: PREDICTED: similar to F-box prot... 33 4.1
UniRef50_A6Q7R1 Cluster: Putative uncharacterized protein; n=1; ... 33 4.1
UniRef50_Q9FNY4 Cluster: DNA polymerase lambda; n=31; Spermatoph... 33 4.1
UniRef50_A5KBH9 Cluster: Putative uncharacterized protein; n=1; ... 33 4.1
UniRef50_Q1N173 Cluster: Secreted/periplasmic Zn-dependent pepti... 33 5.4
UniRef50_Q8MZ38 Cluster: LP06735p; n=3; Drosophila melanogaster|... 33 5.4
UniRef50_Q7Q6F7 Cluster: ENSANGP00000004512; n=2; Diptera|Rep: E... 33 5.4
UniRef50_A7TKI2 Cluster: Putative uncharacterized protein; n=1; ... 33 5.4
UniRef50_UPI00015A6B18 Cluster: UPI00015A6B18 related cluster; n... 33 7.1
UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate dehy... 33 7.1
UniRef50_Q10WZ2 Cluster: Diguanylate cyclase; n=1; Trichodesmium... 33 7.1
UniRef50_A5ZLL3 Cluster: Putative uncharacterized protein; n=1; ... 33 7.1
UniRef50_A5KKL0 Cluster: Putative uncharacterized protein; n=1; ... 33 7.1
UniRef50_A5G2F5 Cluster: O-antigen polymerase precursor; n=1; Ac... 33 7.1
UniRef50_Q177T5 Cluster: Huntingtin interacting protein; n=2; Cu... 33 7.1
UniRef50_A0BF54 Cluster: Chromosome undetermined scaffold_103, w... 33 7.1
UniRef50_A3LYH8 Cluster: Checkpoint kinase 1; n=2; Saccharomycet... 33 7.1
UniRef50_Q3ISB8 Cluster: Transducer protein htr22; n=1; Natronom... 33 7.1
UniRef50_Q09811 Cluster: ATP-dependent DNA helicase hus2/rqh1; n... 33 7.1
UniRef50_UPI00015B4C52 Cluster: PREDICTED: similar to conserved ... 32 9.4
UniRef50_Q3USU0 Cluster: Adult male corpora quadrigemina cDNA, R... 32 9.4
UniRef50_Q9XX94 Cluster: Putative uncharacterized protein; n=1; ... 32 9.4
UniRef50_Q4N857 Cluster: Tash1 protein, putative; n=1; Theileria... 32 9.4
UniRef50_Q18288 Cluster: Ubiquitin conjugating enzyme protein 23... 32 9.4
UniRef50_A2G3C9 Cluster: Putative uncharacterized protein; n=1; ... 32 9.4
UniRef50_Q2HHP7 Cluster: Putative uncharacterized protein; n=1; ... 32 9.4
UniRef50_Q0CEB2 Cluster: Predicted protein; n=2; Trichocomaceae|... 32 9.4
UniRef50_A7TLU5 Cluster: Putative uncharacterized protein; n=1; ... 32 9.4
UniRef50_A6S0G6 Cluster: Predicted protein; n=1; Botryotinia fuc... 32 9.4
UniRef50_A4QQD9 Cluster: Putative uncharacterized protein; n=1; ... 32 9.4
UniRef50_Q8U3N7 Cluster: Putative uncharacterized protein PF0420... 32 9.4
UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum... 32 9.4
UniRef50_Q13029 Cluster: PR domain zinc finger protein 2; n=16; ... 32 9.4
>UniRef50_P26267 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha type I, mitochondrial precursor; n=10;
cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha type I, mitochondrial precursor
- Ascaris suum (Pig roundworm) (Ascaris lumbricoides)
Length = 396
Score = 160 bits (388), Expect = 3e-38
Identities = 73/115 (63%), Positives = 92/115 (80%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+A R+A E+CNAGKGPL++EM TYRYSGHSMSDPGTSYRTR+EVQEVR+TRDPIT FK+K
Sbjct: 260 QAVRWAKEWCNAGKGPLMIEMATYRYSGHSMSDPGTSYRTREEVQEVRKTRDPITGFKDK 319
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVR 348
I+ LVT D++K+ID +VRKE+D A KQ+ T+ E +E + DIYY +VR
Sbjct: 320 IVTAGLVTEDEIKEIDKQVRKEIDAAVKQAHTDKESPVELMLTDIYYNTPAQYVR 374
>UniRef50_Q6NX32 Cluster: Pyruvate dehydrogenase (Lipoamide) alpha
1; n=3; Tetrapoda|Rep: Pyruvate dehydrogenase
(Lipoamide) alpha 1 - Xenopus tropicalis (Western clawed
frog) (Silurana tropicalis)
Length = 369
Score = 138 bits (335), Expect = 7e-32
Identities = 61/112 (54%), Positives = 88/112 (78%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA +FA ++C +GKGP++ME++TYRY GHSMSDPG SYRTR+E+QEVR DPIT K++
Sbjct: 243 EATQFAADHCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPITLLKDR 302
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEP 339
+LN+ L + ++LK+ID +VRKE++EA + + T+PE +EE++ IY N EP
Sbjct: 303 MLNNNLSSVEELKEIDVEVRKEIEEAAQFATTDPEPPLEEIANHIY--NNEP 352
>UniRef50_P08559 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, somatic form, mitochondrial precursor;
n=110; cellular organisms|Rep: Pyruvate dehydrogenase E1
component subunit alpha, somatic form, mitochondrial
precursor - Homo sapiens (Human)
Length = 390
Score = 135 bits (327), Expect = 7e-31
Identities = 62/117 (52%), Positives = 86/117 (73%), Gaps = 1/117 (0%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA RFA YC +GKGP++ME++TYRY GHSMSDPG SYRTR+E+QEVR DPI K++
Sbjct: 264 EATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDR 323
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPF-VRG 351
++N L + ++LK+ID +VRKE+++A + + +PE +EEL IY + PF VRG
Sbjct: 324 MVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSD-PPFEVRG 379
>UniRef50_Q9W4H4 Cluster: CG7024-PA; n=2; Sophophora|Rep: CG7024-PA
- Drosophila melanogaster (Fruit fly)
Length = 479
Score = 128 bits (308), Expect = 1e-28
Identities = 61/127 (48%), Positives = 90/127 (70%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A +FA+++ GP+V+EM TYRY GHSMSDPGTSYR+R+EVQ R+ RDPITSF+ +I
Sbjct: 267 ATQFAVDHA-LKHGPIVLEMSTYRYVGHSMSDPGTSYRSREEVQSTREKRDPITSFRSQI 325
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVRGIHPAA 366
+ L ++LK +D K RK+VD K++ T+ EV ++EL DIY KN++ +RG+
Sbjct: 326 IALCLADEEELKALDDKTRKQVDSICKKATTDREVELDELHTDIYAKNVDGKIRGV-SGF 384
Query: 367 PLKHLEV 387
L+H+++
Sbjct: 385 HLEHIKL 391
>UniRef50_Q1EGI2 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=6; Spirotrichea|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Euplotes sp. BB-2004
Length = 389
Score = 122 bits (293), Expect = 9e-27
Identities = 55/119 (46%), Positives = 79/119 (66%), Gaps = 2/119 (1%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E ++ +YC GKGPL E++TYRY GHSMSDPG +YRTR+EV E R+T+DPI K+
Sbjct: 260 ELYKWGKKYCTDGKGPLFFELQTYRYHGHSMSDPGITYRTREEVNEYRKTQDPILLVKKW 319
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY--YKNLEPFVRGI 354
IL H++ T LK+ID ++R +DE +Q K +P EEL +IY + +P++R +
Sbjct: 320 ILEHDIATEKYLKEIDKEIRARIDEEVEQIKNDPMPAPEELMTEIYEGQETEKPYIRNV 378
>UniRef50_Q8H1Y0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor; n=33; cellular
organisms|Rep: Pyruvate dehydrogenase E1 component
subunit alpha-2, mitochondrial precursor - Arabidopsis
thaliana (Mouse-ear cress)
Length = 393
Score = 118 bits (284), Expect = 1e-25
Identities = 52/109 (47%), Positives = 77/109 (70%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+A +FA E+ GP+++EM+TYRY GHSMSDPG++YRTRDE+ VRQ RDPI ++
Sbjct: 268 QACKFAKEHA-LKNGPIILEMDTYRYHGHSMSDPGSTYRTRDEISGVRQVRDPIERVRKL 326
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKN 330
+L H++ T +LKD++ ++RKEVD+A Q+K P EL ++Y K+
Sbjct: 327 LLTHDIATEKELKDMEKEIRKEVDDAVAQAKESPIPDASELFTNMYVKD 375
>UniRef50_P16387 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha, mitochondrial precursor; n=34;
Dikarya|Rep: Pyruvate dehydrogenase E1 component subunit
alpha, mitochondrial precursor - Saccharomyces
cerevisiae (Baker's yeast)
Length = 420
Score = 114 bits (274), Expect = 2e-24
Identities = 56/122 (45%), Positives = 77/122 (63%), Gaps = 3/122 (2%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+A++FA ++C +GKGPLV+E ETYRY GHSMSDPGT+YRTRDE+Q +R DPI K
Sbjct: 284 QASKFAKDWCLSGKGPLVLEYETYRYGGHSMSDPGTTYRTRDEIQHMRSKNDPIAGLKMH 343
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATK--QSKTEPEVGIEELSADIYYKNLE-PFVRGI 354
+++ + T ++K D RK VDE + + PE + L D+Y K E P +RG
Sbjct: 344 LIDLGIATEAEVKAYDKSARKYVDEQVELADAAPPPEAKLSILFEDVYVKGTETPTLRGR 403
Query: 355 HP 360
P
Sbjct: 404 IP 405
>UniRef50_Q4QDQ1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=5; Euglenozoa|Rep: Pyruvate
dehydrogenase E1 component alpha subunit, putative -
Leishmania major
Length = 378
Score = 109 bits (261), Expect = 7e-23
Identities = 45/106 (42%), Positives = 72/106 (67%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E R+A +YC +GKGP+VME++ YRY GHSMSDP YRT+ ++Q V+Q RD I +E
Sbjct: 255 EGTRYARDYCMSGKGPIVMELDCYRYMGHSMSDPDNQYRTKSDIQHVKQERDCIRKMREF 314
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ ++T D++ ++ V+KEVD+ ++++ +P ++EL DIY
Sbjct: 315 MATEGIMTEDEMSKMEKDVKKEVDQDLQKAQKQPMTKLDELFTDIY 360
>UniRef50_Q5FNM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=4; Bacteria|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Gluconobacter oxydans
(Gluconobacter suboxydans)
Length = 334
Score = 106 bits (255), Expect = 4e-22
Identities = 53/105 (50%), Positives = 72/105 (68%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EAA+ A+EYC +GKGP ++EMETYRY GHSMSDP YR R EV+E+R+TRDPI + K +
Sbjct: 228 EAAQEAMEYCRSGKGPFLLEMETYRYRGHSMSDP-AKYRQRAEVEEMRRTRDPIETLKAE 286
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADI 318
+L + KDI+ V+ V +AT+ ++T PE + EL DI
Sbjct: 287 MLRSG-IEESVFKDIETDVKAIVADATEFAQTSPEPDVSELWTDI 330
>UniRef50_A2QWB4 Cluster: Catalytic activity: Pyruvate + Lipoamide
<=> S-Acetyldihydrolipoamide + CO2; n=3; Ascomycota|Rep:
Catalytic activity: Pyruvate + Lipoamide <=>
S-Acetyldihydrolipoamide + CO2 - Aspergillus niger
Length = 403
Score = 104 bits (249), Expect = 2e-21
Identities = 48/116 (41%), Positives = 77/116 (66%), Gaps = 2/116 (1%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A ++ +Y G GPL+ E +TYRY+GHS+SDPGT+YR+RDEVQ R DPIT+++EK+
Sbjct: 277 AMKYGKDYVLGGNGPLLYEFQTYRYAGHSVSDPGTAYRSRDEVQAER-ANDPITTYREKM 335
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSK--TEPEVGIEELSADIYYKNLEPFVR 348
+ +++ D +K +D ++R +VD ++++ EP + + L DIY + EP R
Sbjct: 336 IEWGVLSEDDVKTMDKEIRSKVDREAQEAEKMAEPPLNSDVLFEDIYVRGSEPAQR 391
>UniRef50_Q9R9N5 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=62; Bacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Rhizobium
meliloti (Sinorhizobium meliloti)
Length = 348
Score = 103 bits (247), Expect = 3e-21
Identities = 48/104 (46%), Positives = 70/104 (67%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AA A+E+C +GKGP+++EM TYRY GHSMSDP YR++DEVQ++R DPI K ++
Sbjct: 244 AADEAVEHCRSGKGPIILEMLTYRYRGHSMSDPA-KYRSKDEVQKMRSEHDPIEQVKARL 302
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADI 318
+ T D+LK ID +VR V ++ ++++PE + EL DI
Sbjct: 303 TDKGWATEDELKQIDKEVRDIVADSADFAQSDPEPDVSELYTDI 346
>UniRef50_O96865 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Trypanosoma cruzi|Rep: Pyruvate dehydrogenase E1
alpha subunit - Trypanosoma cruzi
Length = 378
Score = 102 bits (245), Expect = 6e-21
Identities = 44/106 (41%), Positives = 72/106 (67%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E R+A E+C +GKGP+V+E ++YRY GHSMSDP + YR + ++Q+VR+TRD I K+
Sbjct: 255 EGTRWAKEWCLSGKGPIVLEFDSYRYVGHSMSDPDSQYRKKSDIQDVRKTRDCIHKMKDF 314
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+L ++T +++K ++ V+KEVD+ + ++ + EL DIY
Sbjct: 315 MLEEGIMTDEEMKKLEKDVKKEVDQQLQPAEKQKPTPRSELFTDIY 360
>UniRef50_Q4WHM5 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit, putative; n=1; Aspergillus fumigatus|Rep:
Pyruvate dehydrogenase E1 component alpha subunit,
putative - Aspergillus fumigatus (Sartorya fumigata)
Length = 360
Score = 100 bits (240), Expect = 2e-20
Identities = 49/113 (43%), Positives = 72/113 (63%), Gaps = 2/113 (1%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A + E+ AG GPLV E TYRY+GHSMSDPG YRTR E++ R + DP+++F+ ++
Sbjct: 236 AVKHGREFIRAGNGPLVYEYVTYRYAGHSMSDPGVGYRTRGELKAERAS-DPVSNFRAQL 294
Query: 187 LNHELVTPDQLKDIDAKVRKEVDE--ATKQSKTEPEVGIEELSADIYYKNLEP 339
++ ++T D+ K ID VRK+V+ A + EPE ++ L DIY + EP
Sbjct: 295 IDWGIITEDEAKTIDKNVRKKVNHEVAEAEKMPEPEPRLDVLFQDIYVRGSEP 347
>UniRef50_Q23KL2 Cluster: Pyruvate dehydrogenase E1 component; n=5;
Intramacronucleata|Rep: Pyruvate dehydrogenase E1
component - Tetrahymena thermophila SB210
Length = 429
Score = 98.7 bits (235), Expect = 1e-19
Identities = 49/117 (41%), Positives = 72/117 (61%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E +FA +Y GPL +E+ TYRY GHSMSD GT+YRT++E++E RQ +D I
Sbjct: 301 EGFKFAKQYA-LEHGPLFIELRTYRYHGHSMSDSGTTYRTQEEIKEFRQKKDCIQFIANT 359
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVRGI 354
IL + T +QL+ I + R+ VD+A +Q+ +P EL D+Y N + ++RGI
Sbjct: 360 ILQNNFATQEQLEAIQDETREIVDKAVEQALKDPLPDDHELCTDVYINNDKYYIRGI 416
>UniRef50_A7CXZ4 Cluster: Pyruvate dehydrogenase; n=1; Opitutaceae
bacterium TAV2|Rep: Pyruvate dehydrogenase - Opitutaceae
bacterium TAV2
Length = 365
Score = 89.0 bits (211), Expect = 8e-17
Identities = 38/100 (38%), Positives = 64/100 (64%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P V+E++TYRY GHS++DP +YRTRDE++E R+T+DPI F++ +L +++T +++I
Sbjct: 257 PAVVEIDTYRYRGHSVADPDKTYRTRDEIEEYRKTKDPINLFQQTLLAEKVLTDALIEEI 316
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVR 348
D R E D A ++ P ++ D+Y++ P R
Sbjct: 317 DTAARAEADHAADFAEASPFPTPADIQTDVYWEADNPAQR 356
>UniRef50_O66112 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Proteobacteria|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Zymomonas
mobilis
Length = 354
Score = 83.8 bits (198), Expect = 3e-15
Identities = 43/104 (41%), Positives = 66/104 (63%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AA A+++ AGKGP+++EM+TYRY GHSMSDP YR+R+EV ++++ DP+ + K K
Sbjct: 248 AATVAVDWVQAGKGPIILEMKTYRYRGHSMSDP-ARYRSREEVNDMKENHDPLDNLK-KD 305
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADI 318
L V +L +D +R++V EA ++ P EEL +I
Sbjct: 306 LFAAGVPEAELVKLDEDIRQQVKEAADFAEKAPLPADEELYTNI 349
>UniRef50_Q4T3C0 Cluster: Chromosome undetermined SCAF10102, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF10102,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 491
Score = 83.4 bits (197), Expect = 4e-15
Identities = 39/88 (44%), Positives = 58/88 (65%)
Frame = +1
Query: 112 SYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEV 291
SYRTRDE+QEVR DPI+ K+++L + + + ++ K+ID +RKEV+EA + ++PE
Sbjct: 401 SYRTRDEIQEVRSKSDPISMLKDRMLGNNMASVEEFKEIDISIRKEVEEAAQFCTSDPEP 460
Query: 292 GIEELSADIYYKNLEPFVRGIHPAAPLK 375
+E+L I+ N VRG HP A LK
Sbjct: 461 PLEDLCNHIFCNNPPLGVRGTHPWAVLK 488
>UniRef50_Q8TA29 Cluster: Putative pyruvate dehydrogenase; n=1;
Heterodera glycines|Rep: Putative pyruvate dehydrogenase
- Heterodera glycines (Soybean cyst nematode worm)
Length = 132
Score = 82.6 bits (195), Expect = 7e-15
Identities = 41/77 (53%), Positives = 56/77 (72%)
Frame = +1
Query: 121 TRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIE 300
TRDE+QEVR++RDPITSFK++I+ LVT ++LKDID KVR+EVDEA K + ++ + E
Sbjct: 1 TRDEIQEVRKSRDPITSFKDRIVTAGLVTEEELKDIDKKVRQEVDEAVKVALSDEVLPPE 60
Query: 301 ELSADIYYKNLEPFVRG 351
L +D+Y VRG
Sbjct: 61 TLFSDLYANTPPLAVRG 77
>UniRef50_A6Q3I6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E1 component, alpha subunit; n=2; unclassified
Epsilonproteobacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, E1 component, alpha subunit -
Nitratiruptor sp. (strain SB155-2)
Length = 323
Score = 79.8 bits (188), Expect = 5e-14
Identities = 42/108 (38%), Positives = 62/108 (57%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+A A EY G GP +E ETYRY GHSMSD G YR+ +E+ E+ ++RDPI K++
Sbjct: 211 KAVTEAKEYLENGLGPYFIEAETYRYEGHSMSDNG-KYRSEEEM-EIFKSRDPIEKLKKE 268
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYK 327
+ +V + D +V +E+ EA + + PE + EL D+Y K
Sbjct: 269 AIALGIVEESYFDETDKRVEQEIAEAIEFAANSPEPDLSELYEDVYCK 316
>UniRef50_A4VXG8 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase (E1) component, eukaryotic type,
alpha subunit; n=40; Streptococcus|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex,
dehydrogenase (E1) component, eukaryotic type, alpha
subunit - Streptococcus suis (strain 05ZYH33)
Length = 337
Score = 79.0 bits (186), Expect = 8e-14
Identities = 36/106 (33%), Positives = 68/106 (64%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E + IEY AGKGP ++E+E+YR+ GHS +D G YRT++EV E + +DP+ +++
Sbjct: 232 EKMQEVIEYVRAGKGPAMVEVESYRWFGHSTADAGV-YRTKEEVNEWK-AKDPLKKYRKY 289
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ +++ T ++L I+A+V ++V+ + K ++ P+ I D++
Sbjct: 290 LTENKIATDEELDAIEAQVAEQVEASVKFAQESPDPDISVAYEDVF 335
>UniRef50_A5UU15 Cluster: Pyruvate dehydrogenase; n=3; Chloroflexi
(class)|Rep: Pyruvate dehydrogenase - Roseiflexus sp.
RS-1
Length = 350
Score = 78.6 bits (185), Expect = 1e-13
Identities = 38/107 (35%), Positives = 66/107 (61%), Gaps = 1/107 (0%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA+ A+E+ +GKGP+++E TYR+ GHS D YRT+++++ R+ DPI ++
Sbjct: 233 EASLRAVEHARSGKGPVLLEAMTYRFRGHSAQDT-QKYRTKEDIERHRR-NDPIVRYRTL 290
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELS-ADIY 321
+LN + T Q++DID + +V+ A + + PE G E ++ A +Y
Sbjct: 291 LLNEGIATEQQIRDIDRMIDDQVEAAVRFADESPEPGHEWITQAGVY 337
>UniRef50_Q42066 Cluster: Pyruvate dehydrogenase E1 componen; n=5;
Eukaryota|Rep: Pyruvate dehydrogenase E1 componen -
Arabidopsis thaliana (Mouse-ear cress)
Length = 127
Score = 76.2 bits (179), Expect = 6e-13
Identities = 31/46 (67%), Positives = 38/46 (82%)
Frame = +1
Query: 43 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKE 180
KGP+++EM+TYRY GHSMS PG++YRTRDE+ VRQ RDPI KE
Sbjct: 77 KGPIILEMDTYRYHGHSMSXPGSTYRTRDEISXVRQERDPIERIKE 122
>UniRef50_A5UVY9 Cluster: Pyruvate dehydrogenase; n=2;
Roseiflexus|Rep: Pyruvate dehydrogenase - Roseiflexus
sp. RS-1
Length = 334
Score = 75.8 bits (178), Expect = 8e-13
Identities = 37/106 (34%), Positives = 62/106 (58%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EAA A+E +G GP ++E +TYR+ H+ +D YR +EV+ R RDPI F+
Sbjct: 229 EAAHQAMERARSGGGPTLLECKTYRFRPHTSADDDRRYRKPEEVEAWR-ARDPIKRFEHY 287
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++ H ++T D+++ + +VR EVD AT + P +E ++ +Y
Sbjct: 288 LVEHGIITHDEIEAMRREVRAEVDAATDAALAAPWPPVESIADHVY 333
>UniRef50_Q3J9C5 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Nitrosococcus oceani (strain ATCC 19707 / NCIMB 11848)
Length = 339
Score = 74.5 bits (175), Expect = 2e-12
Identities = 41/113 (36%), Positives = 67/113 (59%), Gaps = 1/113 (0%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EAA+ AI + +G GP +E TYRY GHSMSD G +YR+++EV E Q RDPI ++
Sbjct: 218 EAAQSAIAHVRSGAGPYFLEFLTYRYRGHSMSDAG-AYRSKEEVAEWMQ-RDPIQILAKR 275
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQ-SKTEPEVGIEELSADIYYKNLEP 339
++ +T ++ K ++ V+ E+D Q ++ PE + +L+ + N +P
Sbjct: 276 LIEAGELTEEEFKAMEQAVQSEIDNDIIQFAEESPEPKVADLAKYVLEDNPDP 328
>UniRef50_Q1NYU1 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=1; Candidatus Sulcia muelleri str. Hc
(Homalodisca coagulata)|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Candidatus Sulcia muelleri
str. Hc (Homalodisca coagulata)
Length = 167
Score = 74.5 bits (175), Expect = 2e-12
Identities = 41/114 (35%), Positives = 64/114 (56%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E A AI G GP +++ TYRY GHSM+D T YR++ EV E + RDPI K+
Sbjct: 52 EHAYNAISRARNGNGPTFLDILTYRYRGHSMTDAET-YRSKKEVNE-SKNRDPILLIKKF 109
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFV 345
IL +++VT L ++ K+++E K ++ IE+L + +Y + PF+
Sbjct: 110 ILKNKIVTEKVLNSFQDEINKKINECVKFAELSDSTNIEKLYSVVYNQKDYPFL 163
>UniRef50_Q1AZ54 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 325
Score = 74.5 bits (175), Expect = 2e-12
Identities = 37/94 (39%), Positives = 56/94 (59%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA A+E G+GP ++E TYR+ GH DP T YR R+EV+ R+ RDPI +
Sbjct: 220 EAVSRAVERARRGEGPSLIEAMTYRFRGHYEGDPDT-YRDREEVERWRKERDPILLLANR 278
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEP 285
+ + L + L+ I A+V++EVDEA +++ P
Sbjct: 279 LRSEGLASEQDLEQIRARVQREVDEAAEEALGAP 312
>UniRef50_Q18CB6 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit; n=2; Clostridium
difficile|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase alpha subunit - Clostridium difficile
(strain 630)
Length = 322
Score = 73.7 bits (173), Expect = 3e-12
Identities = 36/106 (33%), Positives = 60/106 (56%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E + A E C G+GP+++E TYR+ GHS SD YRT++E+ E + +DPI K
Sbjct: 217 ETVQKAAEKCRRGEGPVLIESRTYRWLGHSKSDANV-YRTKEEI-ESWKAKDPIEFLKNY 274
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++ + L D+L I ++ +++A + ++ P IE L D+Y
Sbjct: 275 LIENNLSNEDELDKIQEFAKQSIEDAVEFAQNSPNPKIESLLEDVY 320
>UniRef50_A0LTQ9 Cluster: Pyruvate dehydrogenase; n=1; Acidothermus
cellulolyticus 11B|Rep: Pyruvate dehydrogenase -
Acidothermus cellulolyticus (strain ATCC 43068 / 11B)
Length = 342
Score = 73.7 bits (173), Expect = 3e-12
Identities = 39/106 (36%), Positives = 62/106 (58%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+ AR +I C G GP+++E TYR GHS +DPGT YR ++EV E RDP+T ++E
Sbjct: 231 DVARRSIAECRTGGGPVLIEALTYRQGGHSRADPGT-YRPKEEV-EAWLARDPVTCYREH 288
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+L L +I+A+ EVD A ++++T + + AD++
Sbjct: 289 LLASG-YPAGTLDEIEARATAEVDRAVEEARTAAAPDVSLVEADLW 333
>UniRef50_Q1XDM0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=52; cellular organisms|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Porphyra
yezoensis
Length = 346
Score = 73.3 bits (172), Expect = 4e-12
Identities = 38/109 (34%), Positives = 64/109 (58%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+AA+ A++ G GP ++E TYR+ GHS++DP R+R E +E RDPI K+
Sbjct: 240 QAAKQAVQRARQGDGPTLIEALTYRFRGHSLADP-DELRSRQE-KEAWVARDPIKKLKKY 297
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKN 330
IL++E+ +L +I V+ E+++A K + + PE + EL ++ N
Sbjct: 298 ILDNEIANIGELNEIQNAVKTELEQAVKFAISSPEPNMSELKRYLFADN 346
>UniRef50_A3VIE7 Cluster: Tpp-dependent acetoin dehydrogenase e1
alpha-subunit; n=2; Rhodobacterales|Rep: Tpp-dependent
acetoin dehydrogenase e1 alpha-subunit - Rhodobacterales
bacterium HTCC2654
Length = 335
Score = 72.5 bits (170), Expect = 7e-12
Identities = 30/107 (28%), Positives = 61/107 (57%), Gaps = 1/107 (0%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSY-RTRDEVQEVRQTRDPITSFKE 180
E + + C G+GP +E+ETYRY GH + D Y R++DE ++ R+ RDPI F+
Sbjct: 227 ELTQKLVARCRKGEGPFFVELETYRYHGHHVGDINREYYRSKDEEKDWRENRDPIIRFRA 286
Query: 181 KILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+++ + + ++++ ++A++ K+ +A ++ P E+ +Y
Sbjct: 287 YLVDQGIASEEEIEAMNAEIEKDATDAVAYAEAAPYPDASEVDMHVY 333
>UniRef50_Q98FT3 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=6; Bacteria|Rep: Acetoin dehydrogenase
(TPP-dependent) alpha chain - Rhizobium loti
(Mesorhizobium loti)
Length = 342
Score = 71.3 bits (167), Expect = 2e-11
Identities = 34/106 (32%), Positives = 60/106 (56%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA+ A+E AG+GP ++E +TYR+ GHS SD YRT++E+++ RDPIT F+ +
Sbjct: 234 EASYRAVERARAGEGPTLIESKTYRHRGHSKSDRNR-YRTKEEIEDWMSNRDPITLFENE 292
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ + ++ I + V +E+ + + +K P + E +Y
Sbjct: 293 LREFGFIDDKGIEAIRSAVSQEIADGIEFAKASPSPDVSETGNYVY 338
>UniRef50_A0LSF3 Cluster: Pyruvate dehydrogenase; n=5; Bacteria|Rep:
Pyruvate dehydrogenase - Acidothermus cellulolyticus
(strain ATCC 43068 / 11B)
Length = 375
Score = 69.7 bits (163), Expect = 5e-11
Identities = 40/127 (31%), Positives = 67/127 (52%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA R A+ + P ++E +YR GHS+ DP YR+++E Q + DP+T+F+++
Sbjct: 252 EALRDALRKAREERAPSILEAVSYRLRGHSVVDPAR-YRSKEEAQRLL-AHDPVTAFRQR 309
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVRGIHPA 363
+++ +++ D+ IDA+V VD A + + P EL A Y L R + P
Sbjct: 310 LIDVGVLSADEAARIDAEVEAAVDAAVEFADNSPHPSPAELFAHAYAHPLPNMPRAL-PG 368
Query: 364 APLKHLE 384
PL +E
Sbjct: 369 DPLLPIE 375
>UniRef50_Q0RVK8 Cluster: Probable pyruvate dehydrogenase; n=1;
Rhodococcus sp. RHA1|Rep: Probable pyruvate
dehydrogenase - Rhodococcus sp. (strain RHA1)
Length = 344
Score = 69.3 bits (162), Expect = 7e-11
Identities = 35/101 (34%), Positives = 56/101 (55%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A E G GP ++E +TYR +GH DP SYR + EV E + RDP+T ++ ++L +
Sbjct: 241 AFERARGGGGPTLVEAKTYRLNGHYEGDP-QSYRDKAEVAEWAE-RDPVTCYRARLLQQQ 298
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
VT +QL + + E+ A ++ P G +++ DIY
Sbjct: 299 NVTEEQLHTAEREAADEIRTAMTEALNAPPAGKDDIFGDIY 339
>UniRef50_Q1KSF1 Cluster: Apicoplast pyruvate dehydrogenase E1 alpha
subunit; n=1; Toxoplasma gondii|Rep: Apicoplast pyruvate
dehydrogenase E1 alpha subunit - Toxoplasma gondii
Length = 635
Score = 69.3 bits (162), Expect = 7e-11
Identities = 37/105 (35%), Positives = 59/105 (56%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AAR AI+ G+GP ++E TYR+ GHS++DP + +E RDPI SF+E++
Sbjct: 476 AARRAIDRARRGEGPTLIEALTYRFRGHSVADPDEMRAVKQ--KEAWVVRDPIKSFEEEL 533
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ + + AKV+ VD+A K ++T PE ++E I+
Sbjct: 534 KRLGYASDETIAATRAKVKAVVDDAVKFAETSPEPDVQECGQFIF 578
>UniRef50_Q74AD3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=5; Geobacter|Rep: Dehydrogenase complex, E1
component, alpha subunit - Geobacter sulfurreducens
Length = 325
Score = 66.5 bits (155), Expect = 5e-10
Identities = 36/106 (33%), Positives = 62/106 (58%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA ++ E+ P ++E TYR+ GHSM+DPG YR+ EV E+ ++RDPI +F+++
Sbjct: 221 EAVKWGAEWVREHSRPYLIEAMTYRFRGHSMADPG-KYRSAAEV-ELWKSRDPIPNFEKR 278
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++ + T +L + K R V +A ++ P +E+ +DIY
Sbjct: 279 LVEEGIATEAELAAVLEKCRGVVADAVAFAEESPWPEDDEVYSDIY 324
>UniRef50_Q1IQR3 Cluster: Dehydrogenase, E1 component; n=1;
Acidobacteria bacterium Ellin345|Rep: Dehydrogenase, E1
component - Acidobacteria bacterium (strain Ellin345)
Length = 736
Score = 65.7 bits (153), Expect = 8e-10
Identities = 36/111 (32%), Positives = 56/111 (50%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A + AI+Y AGKGP + R HS+SD YR E ++ RDPIT F + +
Sbjct: 262 AFKRAIDYIRAGKGPAFVHGHVIRPYSHSLSDDEKLYRPEAERKD-EANRDPITKFYKWL 320
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEP 339
+ L T +LKD+ V EV +++ ++ P ++ S +Y L+P
Sbjct: 321 VAESLATDKELKDLQTDVDTEVQDSSDRAVEAPIPALDSYSQHLYSSTLDP 371
>UniRef50_A5V4J0 Cluster: Pyruvate dehydrogenase; n=2; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 327
Score = 64.9 bits (151), Expect = 1e-09
Identities = 32/104 (30%), Positives = 57/104 (54%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AAR+AI+ AG+GP +E T+R++GH + + G Y + E+ QTRDP+ + ++
Sbjct: 220 AARWAIDRARAGEGPTFIEATTFRFNGHLIGEAG-GYMDK-ELYAASQTRDPMPILRRRL 277
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADI 318
++ + +L +DA +R E+D A + + EL D+
Sbjct: 278 VDQGIAAAGELDALDASIRAEIDAAVQAAYAADYPDPSELKVDV 321
>UniRef50_A6DTS3 Cluster: Dehydrogenase complex, E1 component, alpha
subunit; n=1; Lentisphaera araneosa HTCC2155|Rep:
Dehydrogenase complex, E1 component, alpha subunit -
Lentisphaera araneosa HTCC2155
Length = 320
Score = 64.5 bits (150), Expect = 2e-09
Identities = 33/97 (34%), Positives = 56/97 (57%)
Frame = +1
Query: 31 CNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTP 210
C P ++ + TYRY GHS+SD G YRT+DEV+ ++ +DPI SF + + +
Sbjct: 225 CKKNSRPALVNVTTYRYQGHSVSDAGL-YRTKDEVKCWKE-KDPINSFYKSMEEQGWIDE 282
Query: 211 DQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ K +D +++ EV +A +K P ++EL+ +Y
Sbjct: 283 EGYKALDKEMKAEVKDALDFAKESPWPPMDELTNHVY 319
>UniRef50_Q5QUK4 Cluster: Alpha keto acid dehydrogenase complex, E1
component, alpha subunit; n=32; Gammaproteobacteria|Rep:
Alpha keto acid dehydrogenase complex, E1 component,
alpha subunit - Idiomarina loihiensis
Length = 395
Score = 64.1 bits (149), Expect = 3e-09
Identities = 38/106 (35%), Positives = 61/106 (57%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA R A+E P+++E +YR SGHS SD T YRTRDE + Q +DP+ ++
Sbjct: 262 EARRLAVEE----NEPVLIEAMSYRMSGHSTSDDPTGYRTRDE-EAGWQAKDPLERLQKW 316
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ + + D +++ A+V+ +V A K+S+ P I+EL D+Y
Sbjct: 317 MTDEGWLDKDHVEEHHAEVKAKVLAALKESEKVPVPHIDELINDVY 362
>UniRef50_Q1ATM5 Cluster: Pyruvate dehydrogenase; n=1; Rubrobacter
xylanophilus DSM 9941|Rep: Pyruvate dehydrogenase -
Rubrobacter xylanophilus (strain DSM 9941 / NBRC 16129)
Length = 353
Score = 63.7 bits (148), Expect = 3e-09
Identities = 32/91 (35%), Positives = 53/91 (58%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P +E TYR + H +D YRT++EV++ R RDPI ++K+L + + +++++I
Sbjct: 254 PYAVEAITYRIAPHGAADFFEKYRTKEEVEKWR-ARDPIGILEKKLLERDALDEERIEEI 312
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ R+ V EA K + E IEEL D+Y
Sbjct: 313 KDEARQRVSEAVKYADESEEPPIEELYTDVY 343
>UniRef50_Q9RPS5 Cluster: TPP-dependent branched-chain alpha-keto
acid dehydrogenase, E1 alpha subunit; n=3;
Lactobacillales|Rep: TPP-dependent branched-chain
alpha-keto acid dehydrogenase, E1 alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 330
Score = 62.5 bits (145), Expect = 8e-09
Identities = 27/107 (25%), Positives = 63/107 (58%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A + A++ KGP ++E+ R + HS D + YR+++E++E+++ D + F++++
Sbjct: 225 AFKEAVKAARGKKGPKLIELMVSRLTSHSADDDQSVYRSKEEIEEMKK-NDAVKLFEKQL 283
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYK 327
L +T + + ID ++R E+++AT +++ P+ + ++Y K
Sbjct: 284 LEEGYLTDEDIAKIDEEIRAEINQATDEAEAMPDPVPTSILEEVYAK 330
>UniRef50_A7HBV0 Cluster: 3-methyl-2-oxobutanoate dehydrogenase;
n=4; Cystobacterineae|Rep: 3-methyl-2-oxobutanoate
dehydrogenase - Anaeromyxobacter sp. Fw109-5
Length = 399
Score = 62.1 bits (144), Expect = 1e-08
Identities = 37/110 (33%), Positives = 59/110 (53%), Gaps = 1/110 (0%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A R A E AG+GP ++E TYR GHS SD +YR E+ E + RDPI + +
Sbjct: 263 ATRRARERAEAGEGPTLLECVTYRVEGHSTSDDPRAYRPA-ELVEPWKKRDPILRMRRYL 321
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKT-EPEVGIEELSADIYYKNL 333
+ + + + I A+VR+E+ K+++ P+ +E L D+Y + L
Sbjct: 322 VRRGALAEAEDERIRAQVREELQRVLKEAEAFAPKPPLESLFEDVYAEPL 371
>UniRef50_Q4QC52 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit, putative; n=3; Leishmania|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit, putative - Leishmania major
Length = 479
Score = 62.1 bits (144), Expect = 1e-08
Identities = 31/97 (31%), Positives = 54/97 (55%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P+++E TYR S HS SD T+YR+RDE++ +T PI F+ + TP+Q +++
Sbjct: 359 PVLVEALTYRLSHHSTSDDSTAYRSRDEIEHFAETFSPIERFEHFVTARGWWTPEQSREV 418
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEP 339
+ R EV ++ + P + L D+ +++L P
Sbjct: 419 VERTRSEVLSELRRQEKLPAWPVSTLCDDV-FEHLTP 454
>UniRef50_P27745 Cluster: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha; n=58; cellular
organisms|Rep: Acetoin:2,6-dichlorophenolindophenol
oxidoreductase subunit alpha - Ralstonia eutropha
(strain ATCC 17699 / H16 / DSM 428 / Stanier
337)(Cupriavidus necator (strain ATCC 17699 / H16 / DSM
428 / Stanier337))
Length = 333
Score = 61.7 bits (143), Expect = 1e-08
Identities = 32/106 (30%), Positives = 54/106 (50%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EAA I G GP ++E + R+ GH D T YR E+ ++R +D + F
Sbjct: 226 EAAGEVIRRAREGGGPSLLECKMVRFYGHFEGDAQT-YRAAGELDDIRANKDCLKLFGRA 284
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ +V ++L ID +V ++ A +++K P+ G E+L D+Y
Sbjct: 285 VTQAGVVAREELDTIDREVAALIEHAVQEAKAAPQPGPEDLLTDVY 330
>UniRef50_Q9KG99 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=1; Bacillus halodurans|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
halodurans
Length = 367
Score = 60.9 bits (141), Expect = 2e-08
Identities = 27/102 (26%), Positives = 55/102 (53%), Gaps = 1/102 (0%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEV-RQTRDPITSFKEKILNH 195
AIE G+GP ++E T R+ H+ +D YR ++E++ ++ +DP+T K I
Sbjct: 243 AIEQARKGRGPTLIEAVTTRFGSHTTADDAKKYRDQEEIERTWKEMQDPLTRLKAYIQAK 302
Query: 196 ELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++ ++ + AK+R+ +DE ++ P+ I ++ +Y
Sbjct: 303 GWLSEEEEAQMKAKIRETIDEELSMAEQYPKPSISQMFEHVY 344
>UniRef50_Q2S150 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Salinibacter ruber DSM 13855|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Salinibacter
ruber (strain DSM 13855)
Length = 470
Score = 60.9 bits (141), Expect = 2e-08
Identities = 33/99 (33%), Positives = 55/99 (55%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P ++E+ TYRY GHS++DP YR E+ + RQ++D I ++ IL+ L T ++ I
Sbjct: 373 PSLLEVRTYRYQGHSITDPA-EYRGEGELDQ-RQSQDAINRLQDYILDRGLATEADMEAI 430
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFV 345
D +V++ V +A + E + DIY + PF+
Sbjct: 431 DEEVKERVKDAIDAANEASFPDEEAIYDDIYTQEDYPFI 469
>UniRef50_Q8ZUR8 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=3; Pyrobaculum|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Pyrobaculum aerophilum
Length = 372
Score = 60.9 bits (141), Expect = 2e-08
Identities = 34/107 (31%), Positives = 60/107 (56%), Gaps = 1/107 (0%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSD-PGTSYRTRDEVQEVRQTRDPITSFKE 180
+ A +A+E G+ P ++E YR+ H+ +D P T YR EV+E R+ DP+ ++
Sbjct: 254 KTAMWAVEKARRGE-PTLVEYVMYRFGPHTTADDPLTKYRDPKEVEEYRRW-DPLARLEK 311
Query: 181 KILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++ + + +K I + +EV EA K+++ P+V EEL D+Y
Sbjct: 312 FLIRQGIYSEGDVKTIWEEAEREVKEAAKEAEALPDVPAEELINDVY 358
>UniRef50_Q9LPL5 Cluster: Branched-chain alpha keto-acid
dehydrogenase E1-alpha subunit; n=13; Magnoliophyta|Rep:
Branched-chain alpha keto-acid dehydrogenase E1-alpha
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 472
Score = 60.1 bits (139), Expect = 4e-08
Identities = 37/135 (27%), Positives = 67/135 (49%), Gaps = 3/135 (2%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A R A E + P+++EM TYR HS SD T YR DE+Q + +R+P+ F++ +
Sbjct: 337 AVRSAREMAVTEQRPVLIEMMTYRVGHHSTSDDSTKYRAADEIQYWKMSRNPVNRFRKWV 396
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY---YKNLEPFVRGIH 357
++ + + + + RK++ +A + ++ + + EL D+Y KNLE G+
Sbjct: 397 EDNGWWSEEDESKLRSNARKQLLQAIQAAEKWEKQPLTELFNDVYDVKPKNLEEQELGLK 456
Query: 358 PAAPLKHLEVQPRNH 402
+ + P H
Sbjct: 457 ELVKKQPQDYPPGFH 471
>UniRef50_P47516 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=5; Mycoplasma|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
genitalium
Length = 358
Score = 60.1 bits (139), Expect = 4e-08
Identities = 30/112 (26%), Positives = 61/112 (54%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA + A Y G GP+++E +YR H+ SD + YRT+ E +E ++ DP+ +
Sbjct: 234 EAMQDAANYARGGNGPVLIEFFSYRQGPHTTSDDPSIYRTKQEEEEGMKS-DPVKRLRNF 292
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEP 339
+ + ++ Q +++ +K+ +E+ A ++ + V ++E+ D Y+ L P
Sbjct: 293 LFDRSILNQAQEEEMFSKIEQEIQAAYEKMVLDTPVSVDEV-FDYNYQELTP 343
>UniRef50_Q8AB00 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=11; cellular organisms|Rep: 2-oxoisovalerate
dehydrogenase beta subunit - Bacteroides
thetaiotaomicron
Length = 678
Score = 59.7 bits (138), Expect = 5e-08
Identities = 27/90 (30%), Positives = 53/90 (58%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A EY + + P++++ R HS SD T YR +E++ V++ DP+ F+ +L ++
Sbjct: 230 AREYAISTRNPVIVQANCVRIGSHSNSDKHTLYRDENELEYVKEA-DPLMKFRRMLLRYK 288
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPE 288
+T ++L I+A+ +KE+ A +++ PE
Sbjct: 289 RLTEEELLQIEAESKKELSAANRKALAAPE 318
>UniRef50_A0LLM4 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 365
Score = 59.7 bits (138), Expect = 5e-08
Identities = 37/115 (32%), Positives = 63/115 (54%), Gaps = 2/115 (1%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQE-VRQTRDPITSFKEK 183
AA+ A++ AG GP +E TYR S H+ +D YR +EV++ VR RDPI F++
Sbjct: 234 AAKEAVDRARAGGGPSFIESVTYRLSMHTTADDPKKYRREEEVEQWVR--RDPIIRFEKY 291
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSA-DIYYKNLEPFV 345
+L L++ + + I +V+ E+ EA ++ E + + D Y+ L P++
Sbjct: 292 LLGRGLLSEESVAGIADEVQAEIKEAEERWTRMTEKPADPMEMFDHAYEELPPYL 346
>UniRef50_Q72GU1 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=2; Thermus thermophilus|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Thermus thermophilus
(strain HB27 / ATCC BAA-163 / DSM 7039)
Length = 367
Score = 59.7 bits (138), Expect = 5e-08
Identities = 30/101 (29%), Positives = 56/101 (55%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A+E G+GP ++E+ YRY HS +D + YR ++EV R+ +DPI F+ +
Sbjct: 250 AVERARRGEGPSLVELRVYRYGPHSSADDDSRYRPKEEVAFWRK-KDPIPRFRRFLEARG 308
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
L + +D+ ++R E++ K+++ V E + AD++
Sbjct: 309 LWNEEWEEDVREEIRAELERGLKEAEEAGPVPPEWMFADVF 349
>UniRef50_Q6MAE2 Cluster: Putative pyruvate dehydrogenase
(Lipoamide), E1 component, alpha chain; n=1; Candidatus
Protochlamydia amoebophila UWE25|Rep: Putative pyruvate
dehydrogenase (Lipoamide), E1 component, alpha chain -
Protochlamydia amoebophila (strain UWE25)
Length = 342
Score = 59.3 bits (137), Expect = 7e-08
Identities = 27/94 (28%), Positives = 57/94 (60%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P+++E+ T R+ GHS+SDPG YR +D ++++ +DPI + + ++ ++T D +K +
Sbjct: 248 PVLVEVVTERFKGHSISDPGL-YRAKDTLKQI-MAKDPILALQAVLIKKGILTEDMVKQM 305
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIYYKN 330
+ + R+++ EA ++ P + L D++ N
Sbjct: 306 NKENREKIIEAMSFAENSPWPDPQTLEEDVFAPN 339
>UniRef50_Q67ME6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1 alpha subunit; n=23; Bacteria|Rep:
Branched-chain alpha-keto acid dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 352
Score = 59.3 bits (137), Expect = 7e-08
Identities = 32/106 (30%), Positives = 52/106 (49%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E + A E G+GP ++E R + HS D YR +E+ V Q RDPI ++
Sbjct: 245 EVVKEAHERARRGEGPTLIEARCIRITSHSSDDDQRRYRDPEEIAAV-QVRDPIRKARQY 303
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ H L+ ++++ KV VD+AT ++ +P EE +Y
Sbjct: 304 LFEHGLMDEAAEQELERKVAAIVDDATDWAEAQPYAAPEEALRHVY 349
>UniRef50_Q1ARM0 Cluster: Pyruvate dehydrogenase; n=3; Bacteria|Rep:
Pyruvate dehydrogenase - Rubrobacter xylanophilus
(strain DSM 9941 / NBRC 16129)
Length = 332
Score = 59.3 bits (137), Expect = 7e-08
Identities = 29/109 (26%), Positives = 61/109 (55%), Gaps = 2/109 (1%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTS--YRTRDEVQEVRQTRDPITSFK 177
EA A+ AG+GP ++E TYR+ GH+ + S YR +E++E + +DPIT+F
Sbjct: 213 EAVSEAVGRARAGEGPSLIEARTYRWHGHNEGEEAFSGPYRPEEEIEEWK-GKDPITTFA 271
Query: 178 EKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYY 324
+++ + ++++ +DA+ ++ +++A + + EE ++Y
Sbjct: 272 ARLVEQGVFAREEIERVDAEEKERIEDAVRFAVESAYPDPEEALMHLFY 320
>UniRef50_Q4DB65 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit, putative; n=3; Trypanosoma|Rep:
2-oxoisovalerate dehydrogenase alpha subunit, putative -
Trypanosoma cruzi
Length = 431
Score = 58.8 bits (136), Expect = 9e-08
Identities = 37/113 (32%), Positives = 57/113 (50%), Gaps = 1/113 (0%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+ R A E P+++E YR S HS SD T YR+RDEV+ P+ F EK
Sbjct: 299 QTVRKARELIRTTNQPVLVEALLYRSSHHSSSDDSTWYRSRDEVEVFSNLFLPVARF-EK 357
Query: 184 ILNHELV-TPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEP 339
L +L+ TP+Q + + KVR+E + + P+ + + D+ YK + P
Sbjct: 358 YLERKLLWTPEQSRSLSQKVRQETLAELHRQEKLPKWPVSSMHDDV-YKEMTP 409
>UniRef50_Q0W151 Cluster: Pyruvate dehydrogenase complex E1,
transketolase alpha subunit; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E1, transketolase alpha subunit - Uncultured
methanogenic archaeon RC-I
Length = 359
Score = 58.4 bits (135), Expect = 1e-07
Identities = 28/94 (29%), Positives = 52/94 (55%)
Frame = +1
Query: 40 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 219
G+GP +E YR+ H+ SD YR++ EV+++R+ DPI F+ ++N L D+
Sbjct: 245 GEGPAFIEAICYRFGPHTTSDNPDLYRSKGEVEKIRKETDPIDRFRNYLVNKGLWDIDKE 304
Query: 220 KDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ ++ +D+A K+++ P EEL ++
Sbjct: 305 TRLHDEMDALIDKAAKEAEQAPAPEFEELFKHVF 338
>UniRef50_Q6YPX5 Cluster: Thiamine pyrophosphate-dependent
dehydrogenase, E1 component alpha subunit; n=2;
Candidatus Phytoplasma asteris|Rep: Thiamine
pyrophosphate-dependent dehydrogenase, E1 component
alpha subunit - Onion yellows phytoplasma
Length = 363
Score = 58.0 bits (134), Expect = 2e-07
Identities = 33/108 (30%), Positives = 60/108 (55%), Gaps = 1/108 (0%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AA+ A G GP ++E +YR HS +D + YR+++E E R+ +DPI F++ +
Sbjct: 235 AAQEAFNEARKGNGPTLIENVSYRLEAHSTNDNASVYRSKEEELEWRK-KDPIVRFQKYL 293
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEA-TKQSKTEPEVGIEELSADIYYK 327
+N +T Q++ + + ++EV A K +T + I+++ A Y K
Sbjct: 294 MNKGYLTQKQVEQFEKEAQEEVVLAHQKVEQTGNNIDIKDIFAYTYEK 341
>UniRef50_A4AFX0 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; marine actinobacterium PHSC20C1|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
marine actinobacterium PHSC20C1
Length = 327
Score = 58.0 bits (134), Expect = 2e-07
Identities = 38/102 (37%), Positives = 53/102 (51%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A + A+E AG+GP ++E +TYR+SGHS SDP YR +EV+ RDPI + I
Sbjct: 226 ATKTAVERARAGEGPTLIEADTYRHSGHSRSDP-AKYRPEEEVKS-WFARDPIVQLRNAI 283
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSA 312
D +++ +VD A + T PE ELSA
Sbjct: 284 --EASGGADAAAEVERTAHTDVDAARDLALTWPE---PELSA 320
>UniRef50_Q8CX87 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=5; Bacillaceae|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit -
Oceanobacillus iheyensis
Length = 358
Score = 57.2 bits (132), Expect = 3e-07
Identities = 27/96 (28%), Positives = 50/96 (52%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A+E G+GP ++E T+RY H+ +D T YR + E E + DPIT + + +
Sbjct: 236 ALERARNGEGPSLIEAVTWRYGAHTTADDPTKYRNQKEENEKHRQNDPITRLELFMKAYG 295
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEEL 306
++ + +V++E+D A K +T P + ++
Sbjct: 296 FWDEAVVEQLKEEVKEEIDGAVKDLETMPPADVNDI 331
>UniRef50_Q3DZ88 Cluster: Dehydrogenase, E1 component; n=1;
Chloroflexus aurantiacus J-10-fl|Rep: Dehydrogenase, E1
component - Chloroflexus aurantiacus J-10-fl
Length = 334
Score = 57.2 bits (132), Expect = 3e-07
Identities = 36/106 (33%), Positives = 58/106 (54%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA R A+ +G GP ++E TYR+ GHS SD +YR+RDEV++ Q+RDPI
Sbjct: 234 EAVRQAVARARSGYGPTLVEAITYRWKGHSKSD-RQAYRSRDEVKD-WQSRDPIMRLARL 291
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
I ++ + K I + R ++EA + ++ PE + + +Y
Sbjct: 292 I----QMSDAEFKAIVDQARTMIEEAVEFAQASPEPDPDTIFEGLY 333
>UniRef50_A4XHV5 Cluster: Transketolase, central region; n=3;
Bacteria|Rep: Transketolase, central region -
Caldicellulosiruptor saccharolyticus (strain ATCC 43494
/ DSM 8903)
Length = 823
Score = 56.0 bits (129), Expect = 7e-07
Identities = 24/68 (35%), Positives = 48/68 (70%)
Frame = +1
Query: 43 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLK 222
+GP+++++ TYR +GHS SD T YRT++E+ E ++DP+ +FK++++ + T D++
Sbjct: 331 QGPVLLDVVTYRLTGHSPSDSST-YRTKEEL-EAWASQDPLVTFKDELIRVGVATEDKIN 388
Query: 223 DIDAKVRK 246
+I V++
Sbjct: 389 EIQQNVKE 396
>UniRef50_Q9RYC1 Cluster: 2-oxo acid dehydrogenase, E1 component,
alpha subunit; n=2; Deinococcus|Rep: 2-oxo acid
dehydrogenase, E1 component, alpha subunit - Deinococcus
radiodurans
Length = 381
Score = 55.6 bits (128), Expect = 9e-07
Identities = 35/110 (31%), Positives = 57/110 (51%), Gaps = 4/110 (3%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGT--SYRTRDEVQEVRQTRDPITSFK 177
E A E+ AG GP ++E TYR HS +D SYRTRDEV E RDPI
Sbjct: 252 EVCHHAAEWVRAGNGPALVECLTYRVGSHSNADADAEKSYRTRDEVNE-WLGRDPIQRV- 309
Query: 178 EKILNH--ELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
E +L H + ++ ++ + A++ K++D+ ++++ + D+Y
Sbjct: 310 ENLLEHLGDPISAEERAGMIAEIHKQIDDDVRRAEAAGYPDWRIMFEDVY 359
>UniRef50_A6W004 Cluster: Transketolase domain protein; n=6;
Proteobacteria|Rep: Transketolase domain protein -
Marinomonas sp. MWYL1
Length = 701
Score = 55.6 bits (128), Expect = 9e-07
Identities = 28/94 (29%), Positives = 53/94 (56%), Gaps = 4/94 (4%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A+EY +GKG ++ ++ R GH+ D T Y+ D + + Q RDP+ K +L++
Sbjct: 250 AVEYVRSGKGTCLLRLKVPRLCGHTFQDTQT-YKNEDFIAD-EQARDPLPKLKRYLLDNG 307
Query: 199 LVTPDQLKDIDAK----VRKEVDEATKQSKTEPE 288
+T D+ D++ + +R VD+A ++ + +PE
Sbjct: 308 FMTADEWHDLEDECYRDIRLSVDKAKERQQPDPE 341
>UniRef50_Q12FH4 Cluster: Pyruvate dehydrogenase; n=37;
Bacteria|Rep: Pyruvate dehydrogenase - Polaromonas sp.
(strain JS666 / ATCC BAA-500)
Length = 337
Score = 55.2 bits (127), Expect = 1e-06
Identities = 31/91 (34%), Positives = 51/91 (56%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P+ +E++TYR+ HSM DP YR + EVQ + TR PI +F ++ +T D+ +
Sbjct: 243 PVFVELKTYRFRAHSMFDPEL-YRDKAEVQAWK-TRGPIHTFTARLKAQGSLTEDEFLVL 300
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
DA + EVD A ++ +E+L D++
Sbjct: 301 DAAAQAEVDAAAAFAEAGTWEPVEDLLRDVH 331
>UniRef50_P37940 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=37; Firmicutes|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Bacillus subtilis
Length = 330
Score = 55.2 bits (127), Expect = 1e-06
Identities = 34/107 (31%), Positives = 57/107 (53%), Gaps = 4/107 (3%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSF--- 174
+A + A E G+GP ++E +YR + HS D +SYR R+EV+E +++ DP+ ++
Sbjct: 224 QAVKEARERARRGEGPTLIETISYRLTPHSSDDDDSSYRGREEVEEAKKS-DPLLTYQAY 282
Query: 175 -KEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSA 312
KE L + + L +I A V + DEA PE ++ + A
Sbjct: 283 LKETGLLSDEIEQTMLDEIMAIVNEATDEAENAPYAAPESALDYVYA 329
>UniRef50_Q3WCG3 Cluster: Pyruvate dehydrogenase; n=4;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. EAN1pec
Length = 332
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/101 (28%), Positives = 50/101 (49%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A+E +G GP ++E T+R+ GH DP +Y + + + DPI F+ ++L
Sbjct: 226 AVERARSGGGPTLVECVTFRFRGHYFGDP-MAYIPAERMAAAVEA-DPIPRFRSRLLETG 283
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ +L +I+A V+EA P ++EL D+Y
Sbjct: 284 VCDEHELDEIEAAAVAAVEEALTAVLAAPVAALDELDRDVY 324
>UniRef50_Q02C52 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 340
Score = 54.8 bits (126), Expect = 2e-06
Identities = 30/106 (28%), Positives = 55/106 (51%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA + A+ + G GP ++E +T+R +GHS D T Y + +E + DPI +++
Sbjct: 234 EATQRAVTHARGGLGPYLLECKTFRMTGHSAHDAAT-YVPKGLFEEWGKL-DPIVRLEKR 291
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+L +++ ++ A V +EVD+A ++ P L D+Y
Sbjct: 292 MLEERWSLQEEIDELHAAVIREVDDAVAWAEQSPYPDAASLLDDVY 337
>UniRef50_A3CMZ3 Cluster: Pyruvate dehydrogenase, TPP-dependent E1
component alpha-subunit, putative; n=22; Bacteria|Rep:
Pyruvate dehydrogenase, TPP-dependent E1 component
alpha-subunit, putative - Streptococcus sanguinis
(strain SK36)
Length = 357
Score = 54.8 bits (126), Expect = 2e-06
Identities = 31/106 (29%), Positives = 55/106 (51%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+ A+ A+E G+GP ++E TYR GH D Y+ + ++ D + F++
Sbjct: 251 QVAKEAVERARRGEGPTLIEAVTYRDHGHFEGDE-QKYKALEGEEKDWADVDALDVFRDY 309
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ H L+T ++L I + RK+V+EA K ++ P E L D++
Sbjct: 310 AIEHGLLTEEELDAILEESRKDVEEAIKFAQDSPIPRSESLLEDVF 355
>UniRef50_Q97YF6 Cluster: Pyruvate dehydrogenase, alpha subunit
(Lipoamide); n=2; Sulfolobaceae|Rep: Pyruvate
dehydrogenase, alpha subunit (Lipoamide) - Sulfolobus
solfataricus
Length = 345
Score = 54.8 bits (126), Expect = 2e-06
Identities = 32/81 (39%), Positives = 43/81 (53%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
AIE G GP ++E TYRY GH D G YRT++EV E + DPI + ++L
Sbjct: 246 AIERARKGFGPTLIEALTYRYVGHFEGD-GEEYRTKEEV-EFWSSLDPIRRLENRLLRLN 303
Query: 199 LVTPDQLKDIDAKVRKEVDEA 261
D L + + RK+V EA
Sbjct: 304 YADSDILARLREEARKQVQEA 324
>UniRef50_Q020J5 Cluster: Dehydrogenase, E1 component; n=1;
Solibacter usitatus Ellin6076|Rep: Dehydrogenase, E1
component - Solibacter usitatus (strain Ellin6076)
Length = 697
Score = 54.4 bits (125), Expect = 2e-06
Identities = 31/118 (26%), Positives = 56/118 (47%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+A + A+ YC G GP ++ R HS+SD Y+T E + RDP+ F +
Sbjct: 233 QAMQAAVRYCREGSGPALVHAHCIRPYSHSLSDDERLYKTPAE-RAAEAERDPVLRFPKL 291
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVRGIH 357
+++ ++ L+DI ++ +E+ +AT Q+ E + Y +L+P H
Sbjct: 292 LIDEGVLDRRMLQDITHEIDEEIQQAT-QTALHDEPPSPASALVHLYSDLDPCAPAFH 348
>UniRef50_Q4MTG0 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=38; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus cereus
Length = 371
Score = 54.4 bits (125), Expect = 2e-06
Identities = 32/108 (29%), Positives = 58/108 (53%), Gaps = 1/108 (0%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTRDPITSFKEK 183
A FA E G+GP ++E T+RY H+M+ D T YRT+D E Q +DPI F+
Sbjct: 247 ATAFARERAVNGEGPTLIETLTFRYGPHTMAGDDPTRYRTKDIENEWEQ-KDPIVRFRAF 305
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYK 327
+ N L + + + + + ++++ +A ++ P+ + +L +Y K
Sbjct: 306 LENKGLWSQEVEEKVIEEAKEDIKQAIAKADQAPKQKVTDLMEIMYEK 353
>UniRef50_Q835M4 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=10; Bacilli|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Enterococcus faecalis (Streptococcus faecalis)
Length = 371
Score = 53.6 bits (123), Expect = 4e-06
Identities = 29/105 (27%), Positives = 61/105 (58%), Gaps = 1/105 (0%)
Frame = +1
Query: 10 ARFAIEYCNAGKGPLVMEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A+ A ++ AG GP+++E TYRY H++S D T YR+++ E Q +DP+T F++ +
Sbjct: 248 AKEARDWSAAGNGPVLIETLTYRYGPHTLSGDDPTRYRSKEMDDEWVQ-KDPLTRFRKYL 306
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ L + + ++I K ++E+ A ++ P+ + + +++
Sbjct: 307 TDKGLWSEAKEEEIIEKTKEEIKVAIAEADKAPKQKVSDFLKNMF 351
>UniRef50_Q67SE7 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Bacilli|Rep: Pyruvate dehydrogenase E1 alpha
subunit - Symbiobacterium thermophilum
Length = 368
Score = 53.6 bits (123), Expect = 4e-06
Identities = 30/110 (27%), Positives = 57/110 (51%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
AIE +G GP ++E T+RY H+ SD YR+++E++E Q RDPI + +++
Sbjct: 242 AIERARSGGGPTLVESVTFRYGPHTTSDDPKRYRSQEELEE-WQARDPIERLRLYLVSQG 300
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVR 348
+ + + R++V A +++ P +++L +Y + VR
Sbjct: 301 QWSDSDDEALWTAAREQVAAAVAEAEAMPRPSVDDLFDYLYAEPTPNLVR 350
>UniRef50_Q2JA37 Cluster: Pyruvate dehydrogenase; n=11;
Actinomycetales|Rep: Pyruvate dehydrogenase - Frankia
sp. (strain CcI3)
Length = 388
Score = 53.6 bits (123), Expect = 4e-06
Identities = 29/103 (28%), Positives = 50/103 (48%)
Frame = +1
Query: 13 RFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILN 192
R A+E+ +G+GP+++E TYR H+ +D T YRT +EV Q RDP+T + ++
Sbjct: 258 RAAVEHARSGRGPVLVEAVTYRLEAHTNADDATRYRTSEEV-AAWQARDPLTLLERQLRK 316
Query: 193 HELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
L+ + + + E Q P++ L +Y
Sbjct: 317 AGLLDDAGVAAVARAAEELAAEMRAQFDRVPDLDPGSLFTHVY 359
>UniRef50_Q6A611 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Propionibacterium acnes|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit -
Propionibacterium acnes
Length = 381
Score = 53.2 bits (122), Expect = 5e-06
Identities = 34/106 (32%), Positives = 53/106 (50%), Gaps = 3/106 (2%)
Frame = +1
Query: 13 RFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILN 192
R A+EY +GKGP+ +E TYR H+ +D T YRT +E +T DPI + + N
Sbjct: 259 RSALEYARSGKGPVFVEAWTYRMGAHTTTDDPTRYRTAEEESTWGKT-DPIVRLRTYLQN 317
Query: 193 HELVTP---DQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++ D L + + EV A ++ T + +L AD+Y
Sbjct: 318 RGIINQVWLDGLAEREDAFGAEVRAAVHENATPV---MADLMADVY 360
>UniRef50_Q49108 Cluster: Pyruvate dehydrogenase EI alpha subunit;
n=5; Mollicutes|Rep: Pyruvate dehydrogenase EI alpha
subunit - Mycoplasma capricolum
Length = 370
Score = 53.2 bits (122), Expect = 5e-06
Identities = 24/77 (31%), Positives = 46/77 (59%)
Frame = +1
Query: 22 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHEL 201
+EY G GP+++E +TYR HS SD +YR + E +E+ + DP+ K+ +++ ++
Sbjct: 242 VEYVRKGNGPVLVECDTYRLGAHSSSDNPDAYRPKGEFEEMAKF-DPLIRLKQYLIDKKI 300
Query: 202 VTPDQLKDIDAKVRKEV 252
+ +Q ++A+ K V
Sbjct: 301 WSDEQQAQLEAEQDKFV 317
>UniRef50_A0LFE6 Cluster: Pyruvate dehydrogenase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: Pyruvate
dehydrogenase - Syntrophobacter fumaroxidans (strain DSM
10017 / MPOB)
Length = 320
Score = 52.8 bits (121), Expect = 6e-06
Identities = 27/95 (28%), Positives = 55/95 (57%)
Frame = +1
Query: 37 AGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQ 216
AG+GP ++E +TYR GH SD Y+ +E+ ++ R P+ ++++L EL+
Sbjct: 227 AGEGPSLIECKTYRCRGHGESD-HQLYQPPEEIASWKE-RCPLPRLRDEVLAQELLDEKA 284
Query: 217 LKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
LK ++ ++ + V++A + ++ P E+ +D+Y
Sbjct: 285 LKSMEDEISRIVEDAVRFAEESPWPDPEDALSDVY 319
>UniRef50_Q3E8Q6 Cluster: Uncharacterized protein At5g34780.1; n=1;
Arabidopsis thaliana|Rep: Uncharacterized protein
At5g34780.1 - Arabidopsis thaliana (Mouse-ear cress)
Length = 365
Score = 52.8 bits (121), Expect = 6e-06
Identities = 28/99 (28%), Positives = 54/99 (54%), Gaps = 3/99 (3%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P+++EM YR HS SD T YR DE+Q + +R+ + F++ + ++ + + +
Sbjct: 121 PVLIEMMIYRVGHHSTSDDSTKYRAADEIQYWKMSRNSVNRFRKSVEDNGWWSEEDESKL 180
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIY---YKNLE 336
+ RK++ +A + ++ + + EL D+Y KNLE
Sbjct: 181 RSNARKQLLQAIQAAEKWEKQPLTELFNDVYDVKPKNLE 219
>UniRef50_A6GG24 Cluster: Pyruvate dehydrogenase (Lipoamide), alpha
subunit; n=1; Plesiocystis pacifica SIR-1|Rep: Pyruvate
dehydrogenase (Lipoamide), alpha subunit - Plesiocystis
pacifica SIR-1
Length = 339
Score = 52.4 bits (120), Expect = 8e-06
Identities = 28/80 (35%), Positives = 47/80 (58%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P ++E+ TYR+ GHSMSDP YR + E++ R +RD I + ++ ++ D+L I
Sbjct: 244 PTLIEILTYRFRGHSMSDP-AKYRAKGELEAFR-SRDAIELSRRVLMEQHGMSEDELDAI 301
Query: 229 DAKVRKEVDEATKQSKTEPE 288
D +V +E+D A + P+
Sbjct: 302 DDEVIEEMDAAYTFADESPQ 321
>UniRef50_A0UXT3 Cluster: Pyruvate dehydrogenase; n=1; Clostridium
cellulolyticum H10|Rep: Pyruvate dehydrogenase -
Clostridium cellulolyticum H10
Length = 321
Score = 52.4 bits (120), Expect = 8e-06
Identities = 32/108 (29%), Positives = 58/108 (53%), Gaps = 2/108 (1%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGH--SMSDPGTSYRTRDEVQEVRQTRDPITSFK 177
E A AIE C G+GP ++E +YR+ GH ++ D G YR+++E + ++ PI +K
Sbjct: 213 EYAEKAIERCRKGEGPTLLECVSYRWKGHIGTVDDLGVGYRSQEE-YDYWISKCPIKWYK 271
Query: 178 EKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ + ++ K I+ ++ K V +A + + P+ EEL +Y
Sbjct: 272 DYLRVRNILDDKLEKSINEEIDKLVKDAFEFAVNSPKPQPEELFDFVY 319
>UniRef50_A6CP23 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Bacillus sp. SG-1|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Bacillus
sp. SG-1
Length = 364
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/90 (27%), Positives = 45/90 (50%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A+E G+GP ++E T+RY H+ +D T YR + E E R+ DPI + +
Sbjct: 242 ALERARNGEGPTLIEAVTWRYGAHTTADDPTKYRDQSESDERRKLGDPIARLQRYMERQG 301
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPE 288
+ + + E+D+A ++ ++ PE
Sbjct: 302 WWDQEWADSVQKEYTAEMDQAVEELESYPE 331
>UniRef50_Q9Z8N4 Cluster: Pyruvate Dehydrogenase Alpha; n=8;
Chlamydiaceae|Rep: Pyruvate Dehydrogenase Alpha -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 342
Score = 51.6 bits (118), Expect = 1e-05
Identities = 29/103 (28%), Positives = 57/103 (55%)
Frame = +1
Query: 13 RFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILN 192
R A Y + P+++E R+ GHS+SDP YR+++E+Q + + +DPI K+ ++
Sbjct: 241 REAYRYMVDTESPVLVECLCSRFRGHSISDPNL-YRSKEEMQCLFK-KDPIVLAKDWLIR 298
Query: 193 HELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
E++T ++ ++I + + V EA +K + + L +Y
Sbjct: 299 LEVLTEEEFQNIRQECKTAVLEAFSNAKLSSDPSVTTLEEGVY 341
>UniRef50_Q5SJR9 Cluster: Pyruvate dehydrogenase (Lipoamide) (EC
1.2.4.1) E1-alpha chain; n=2; Thermus thermophilus|Rep:
Pyruvate dehydrogenase (Lipoamide) (EC 1.2.4.1) E1-alpha
chain - Thermus thermophilus (strain HB8 / ATCC 27634 /
DSM 579)
Length = 346
Score = 50.8 bits (116), Expect = 3e-05
Identities = 28/104 (26%), Positives = 53/104 (50%)
Frame = +1
Query: 10 ARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKIL 189
A+ A+E G+GP ++E TYR + H+ SD + YR+++E +E + +DPI ++ +
Sbjct: 220 AKKAVERARKGEGPTLLEALTYRLAPHTTSDDPSRYRSKEE-EEAWRAKDPILRLRKALE 278
Query: 190 NHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
L + K + ++ +E + PE EE+ +Y
Sbjct: 279 GRGLWGEEAEKALLLELEEEFQRELALADEAPEPRPEEIVEHVY 322
>UniRef50_A7K3C9 Cluster: Dehydrogenase E1 component superfamily;
n=10; Gammaproteobacteria|Rep: Dehydrogenase E1
component superfamily - Vibrio sp. Ex25
Length = 398
Score = 50.8 bits (116), Expect = 3e-05
Identities = 32/110 (29%), Positives = 55/110 (50%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+A + A+E GKG ++E +YR S H+ +D T YR D+VQ Q +PI K
Sbjct: 267 DATKTALERARKGKGATLIEAVSYRLSDHTTADDATRYRKEDDVQTAWQ-YEPIARLKTY 325
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNL 333
+LN + +Q + +++V+ A ++ + P E D Y++L
Sbjct: 326 LLNQGAWSDEQEQQWLEYCKEQVELAVERYLSLPSQA-PETGFDYLYESL 374
>UniRef50_Q749T8 Cluster: Pyruvate dehydrogenase complex E1
component, alpha subunit; n=4; Geobacter|Rep: Pyruvate
dehydrogenase complex E1 component, alpha subunit -
Geobacter sulfurreducens
Length = 352
Score = 50.4 bits (115), Expect = 3e-05
Identities = 26/82 (31%), Positives = 43/82 (52%)
Frame = +1
Query: 40 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 219
G GP +E TYR + H+ +D + YR +V+ R RDP+ F+ + L D
Sbjct: 245 GGGPTFIECLTYRMADHTTADDASRYRPPADVEAWRD-RDPLLRFERFLAKRGLWNGDYG 303
Query: 220 KDIDAKVRKEVDEATKQSKTEP 285
++ AK E+DEA ++ ++ P
Sbjct: 304 AEVQAKAEGEIDEAVRRYESVP 325
>UniRef50_Q97CK0 Cluster: 2-oxoisovalerate dehydrogenase alpha
subunit; n=2; Thermoplasma|Rep: 2-oxoisovalerate
dehydrogenase alpha subunit - Thermoplasma volcanium
Length = 337
Score = 50.4 bits (115), Expect = 3e-05
Identities = 29/105 (27%), Positives = 56/105 (53%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A + A+EY +G P+++E +YR HS SD + YR ++EV+E DP+ ++ +
Sbjct: 219 AVKEAVEYARSGN-PILVEARSYRMGPHSTSDDPSKYR-QNEVKE-GDENDPLVIAEKAV 275
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++ +++ ++ I + RK +DE ++ P L D+Y
Sbjct: 276 ISKGILSQSEVNRIKDESRKMIDEKFEERLKIPAPDPSTLFDDVY 320
>UniRef50_Q4A1S8 Cluster: Putative uncharacterized protein; n=4;
Caenorhabditis|Rep: Putative uncharacterized protein -
Caenorhabditis elegans
Length = 432
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/91 (30%), Positives = 44/91 (48%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P+++E TYR HS SD T+YR+ DEVQ PIT FK+ I ++ +
Sbjct: 307 PVLIEAMTYRLGHHSTSDDSTAYRSSDEVQTWGDKDHPITRFKKYITERGWWNEEKEMEW 366
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+V+K V ++ + +L D+Y
Sbjct: 367 QKEVKKRVLTEFAAAEKRKKAHYHDLFEDVY 397
>UniRef50_P12694 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha, mitochondrial precursor; n=29; Euteleostomi|Rep:
2-oxoisovalerate dehydrogenase subunit alpha,
mitochondrial precursor - Homo sapiens (Human)
Length = 445
Score = 50.0 bits (114), Expect = 4e-05
Identities = 28/91 (30%), Positives = 49/91 (53%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P ++E TYR HS SD ++YR+ DEV + PI+ + +L+ +Q K
Sbjct: 323 PFLIEAMTYRIGHHSTSDDSSAYRSVDEVNYWDKQDHPISRLRHYLLSQGWWDEEQEKAW 382
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ R++V EA +Q++ +P+ L +D+Y
Sbjct: 383 RKQSRRKVMEAFEQAERKPKPNPNLLFSDVY 413
>UniRef50_Q8SQM8 Cluster: PYRUVATE DEHYDROGENASE E1 COMPONENT ALPHA
SUBUNIT; n=1; Encephalitozoon cuniculi|Rep: PYRUVATE
DEHYDROGENASE E1 COMPONENT ALPHA SUBUNIT -
Encephalitozoon cuniculi
Length = 349
Score = 49.6 bits (113), Expect = 6e-05
Identities = 30/94 (31%), Positives = 55/94 (58%), Gaps = 2/94 (2%)
Frame = +1
Query: 13 RFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILN 192
++A +Y + GP++++++TYR+ HS +D SYR+R+EV + + RD + ++L
Sbjct: 250 KYARKY-SVENGPIIVQIDTYRFCTHSAADERESYRSREEV-DAEKKRDCMEDVGRRLLA 307
Query: 193 -HELVTPDQLK-DIDAKVRKEVDEATKQSKTEPE 288
+ D L+ I A+V ++VD A K TE +
Sbjct: 308 FYSEEELDALRSSILAEVERDVDAARKSRPTEED 341
>UniRef50_Q3DYK5 Cluster: Dehydrogenase, E1 component; n=3;
Bacteria|Rep: Dehydrogenase, E1 component - Chloroflexus
aurantiacus J-10-fl
Length = 321
Score = 49.2 bits (112), Expect = 8e-05
Identities = 30/105 (28%), Positives = 54/105 (51%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A + A+E AG GP +E +T R GH++ D +Y ++ + E + RDPI +E +
Sbjct: 218 ATKEAVERARAGGGPTFIECKTMRMRGHAIHD-NMAYVPKELLAE-WEARDPIARIEEVL 275
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ L+ +L + A++ E+DEA ++ P L+ +Y
Sbjct: 276 RSRGLLDDAKLAALLARIEAELDEAQAFAEASPYPDPATLTDGVY 320
>UniRef50_A7BPK6 Cluster: Pyruvate dehydrogenase; n=1; Beggiatoa sp.
PS|Rep: Pyruvate dehydrogenase - Beggiatoa sp. PS
Length = 331
Score = 49.2 bits (112), Expect = 8e-05
Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 2/106 (1%)
Frame = +1
Query: 10 ARFAIEYCNAGKGPLVMEMETYRYSGH--SMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
AR AI G+GP +E++TYR+ H D YR E+ ++ R P+ FK
Sbjct: 225 AREAINRTRRGEGPQFLELDTYRWLEHCGPNDDDNLGYRPAGELMSWKK-RCPVEQFKNL 283
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+L + VT +++ ++ +V E++ A + P ++ +Y
Sbjct: 284 LLESQKVTHTEIQQVENEVLHEIEAAFSYALESPNPTSASMADKVY 329
>UniRef50_P35485 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=2; Firmicutes|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Acholeplasma
laidlawii
Length = 345
Score = 49.2 bits (112), Expect = 8e-05
Identities = 27/89 (30%), Positives = 51/89 (57%), Gaps = 1/89 (1%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTRDPITSFKEK 183
A++ A++ G GP ++E TYR H+ S DP + YRT++E E + +D I FK
Sbjct: 218 ASKEAMDRARKGDGPTLIEAFTYRMGPHTTSDDPCSIYRTKEEENEWAK-KDQIARFKTY 276
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQ 270
++N + ++ K ++ +V E+++ K+
Sbjct: 277 LINKGYWSEEEDKKLEEEVLAEINDTFKK 305
>UniRef50_Q9VHB8 Cluster: CG8199-PA; n=2; Eukaryota|Rep: CG8199-PA -
Drosophila melanogaster (Fruit fly)
Length = 439
Score = 48.8 bits (111), Expect = 1e-04
Identities = 30/94 (31%), Positives = 46/94 (48%), Gaps = 4/94 (4%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A + A EY P+V E YR HS SD T+YR +E++ PI+ K +
Sbjct: 303 AMKAAREYVLKENKPVVFEALAYRVGHHSTSDDSTAYRPAEEIEIWNSVEHPISKLKRYM 362
Query: 187 LN----HELVTPDQLKDIDAKVRKEVDEATKQSK 276
++ E V + +KDI KV K++ + K+ K
Sbjct: 363 VHKGWFDETVENEYVKDIRKKVLKQIAVSEKKLK 396
>UniRef50_P21873 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=33; Bacilli|Rep: Pyruvate dehydrogenase
E1 component subunit alpha - Bacillus stearothermophilus
(Geobacillus stearothermophilus)
Length = 369
Score = 48.4 bits (110), Expect = 1e-04
Identities = 31/113 (27%), Positives = 62/113 (54%), Gaps = 1/113 (0%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMS-DPGTSYRTRDEVQEVRQTRDPITSFKEK 183
A + A E G+GP ++E +RY H+MS D T YR++ E++ +DP+ F++
Sbjct: 245 AVKAARERAINGEGPTLIETLCFRYGPHTMSGDDPTRYRSK-ELENEWAKKDPLVRFRKF 303
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPF 342
+ L + ++ ++ + ++E+ EA K++ P+ + +L I ++ L PF
Sbjct: 304 LEAKGLWSEEEENNVIEQAKEEIKEAIKKADETPKQKVTDL-ISIMFEEL-PF 354
>UniRef50_Q5KUY4 Cluster: Pyruvate dehydrogenase E1 (Lipoamide)
alpha subunit; n=2; Geobacillus|Rep: Pyruvate
dehydrogenase E1 (Lipoamide) alpha subunit - Geobacillus
kaustophilus
Length = 359
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/86 (32%), Positives = 44/86 (51%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E + A+E G+GP+++E TYR H+ +D T YR +EV E + +DP+ +
Sbjct: 231 ETMKQAVEAARRGEGPMLIEALTYRLGPHTTADDPTKYRRPEEV-ETWRAKDPLRRLRLL 289
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEA 261
+ L T Q + A+V EV A
Sbjct: 290 LERRGLWTEAQEDALVAQVNDEVTAA 315
>UniRef50_Q2ITF8 Cluster: Acetoin dehydrogenase (TPP-dependent)
alpha chain; n=1; Rhodopseudomonas palustris HaA2|Rep:
Acetoin dehydrogenase (TPP-dependent) alpha chain -
Rhodopseudomonas palustris (strain HaA2)
Length = 323
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/97 (28%), Positives = 47/97 (48%), Gaps = 2/97 (2%)
Frame = +1
Query: 37 AGKGPLVMEMETYRYSGHSMS--DPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTP 210
AG+GP E ETYR+ H D YR+ E E + RDP+ + + ++ +V+
Sbjct: 224 AGEGPRFYEFETYRWREHCGPNYDNDIGYRSAAEY-EAWKLRDPVPALQRALIGEGVVSE 282
Query: 211 DQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ + A++ E+DEA ++ P E D+Y
Sbjct: 283 SGIAAMQAEIDAEIDEAFAFAEASPFPDAGEAFTDVY 319
>UniRef50_Q8U4T5 Cluster: 2-oxo acid dehydrogenase subunit E1; n=1;
Haloferax volcanii|Rep: 2-oxo acid dehydrogenase subunit
E1 - Halobacterium volcanii (Haloferax volcanii)
Length = 353
Score = 47.6 bits (108), Expect = 2e-04
Identities = 28/95 (29%), Positives = 47/95 (49%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EAA A+ G GP ++E++ +R GH M D +YR ++ +Q RD I
Sbjct: 223 EAAGEAVMRARDGNGPTLIEVQVHRRMGHFMGD-AEAYRPEADIDRAKQ-RDSIERLAAD 280
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPE 288
+ +H VT D + ++ + V+ A +K +PE
Sbjct: 281 LRSHG-VTDDDIDEMRERAHGRVEAAISWAKEQPE 314
>UniRef50_Q8EVQ2 Cluster: Pyruvate dehydrogenase E1 component
subunit alpha; n=1; Mycoplasma penetrans|Rep: Pyruvate
dehydrogenase E1 component subunit alpha - Mycoplasma
penetrans
Length = 359
Score = 47.2 bits (107), Expect = 3e-04
Identities = 31/111 (27%), Positives = 57/111 (51%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+A R A Y K P+++E TYR H+ SD YR+ +E + ++ +DPI +
Sbjct: 233 DAIRAARAYVLENKKPILVEFVTYRKGPHTTSDNPRIYRS-EEYECEQEKKDPILRLERW 291
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLE 336
+ + L+ + I K EV+EA K +++ V ++++ D +K L+
Sbjct: 292 MAQNGLLDESKKAQIIEKADAEVEEAYKIMESKLSVSVDDV-FDHTFKTLD 341
>UniRef50_Q7NLM8 Cluster: Gll1094 protein; n=1; Gloeobacter
violaceus|Rep: Gll1094 protein - Gloeobacter violaceus
Length = 481
Score = 47.2 bits (107), Expect = 3e-04
Identities = 25/101 (24%), Positives = 49/101 (48%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
AI G GP ++ +E R H+ SD YR ++E+ + Q RDP++ ++N
Sbjct: 218 AITKARQGNGPTILWVELDRLVSHTNSDDHRIYRPKEEIDAMLQ-RDPLSVLARHLINAG 276
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+T + + + K +DE +Q++ E +++ +Y
Sbjct: 277 ELTATEWQALQFKTAMTIDEIYQQAERENSPNPDQILVHLY 317
>UniRef50_A4F1Y5 Cluster: Branched-chain alpha-keto acid
decarboxylase; n=1; Streptomyces virginiae|Rep:
Branched-chain alpha-keto acid decarboxylase -
Streptomyces virginiae
Length = 677
Score = 47.2 bits (107), Expect = 3e-04
Identities = 27/105 (25%), Positives = 48/105 (45%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AA + AG+GP V+ R H+ SD YRT+DE+ + RDP+ F +++
Sbjct: 237 AAAAVLPDVRAGRGPAVLWCRLDRLDSHTSSDDQRLYRTKDELAAM---RDPVALFTDRL 293
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ P + A++ +V+E + EP E+ ++
Sbjct: 294 EAEGTIVPGWADQVRARLADDVEEVFDRVAGEPSADPGEVMDHLF 338
>UniRef50_Q53610 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit; n=16;
Actinomycetales|Rep: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit - Streptomyces
avermitilis
Length = 406
Score = 45.6 bits (103), Expect = 0.001
Identities = 21/51 (41%), Positives = 31/51 (60%)
Frame = +1
Query: 13 RFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 165
++A+E G+GP ++E TYR H+ SD T YR DE +E + +DPI
Sbjct: 269 KWALERARRGEGPTLVEAFTYRMGAHTTSDDPTKYRA-DEEREAWEAKDPI 318
>UniRef50_Q2J998 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
CcI3|Rep: Pyruvate dehydrogenase - Frankia sp. (strain
CcI3)
Length = 417
Score = 45.6 bits (103), Expect = 0.001
Identities = 20/50 (40%), Positives = 32/50 (64%)
Frame = +1
Query: 16 FAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 165
+A++ +G+GP+++E TYR + H+ SD T Y+ DE+ Q RDPI
Sbjct: 297 WALDRARSGRGPVLIEANTYRMAPHTTSDDATRYQPPDEI-TAWQARDPI 345
>UniRef50_Q0RLC2 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=2; Bacteria|Rep: Pyruvate dehydrogenase E1
component, alpha subunit - Frankia alni (strain ACN14a)
Length = 342
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/105 (28%), Positives = 50/105 (47%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AA AIE G GP ++E T+R+ GH M D Y +E++ DP+ F+ ++
Sbjct: 232 AAGAAIERARTGGGPTLLEAMTFRFCGHIMGDQQV-YMPPEELR-AAIAADPLVRFRAQL 289
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
V D+L ++ EV +A + ++T L+ D+Y
Sbjct: 290 AAD--VGEDELAAVERAAADEVADAWEFARTAELPAASALTTDVY 332
>UniRef50_A0DAM1 Cluster: Chromosome undetermined scaffold_43, whole
genome shotgun sequence; n=3; Oligohymenophorea|Rep:
Chromosome undetermined scaffold_43, whole genome
shotgun sequence - Paramecium tetraurelia
Length = 406
Score = 45.6 bits (103), Expect = 0.001
Identities = 29/105 (27%), Positives = 43/105 (40%), Gaps = 2/105 (1%)
Frame = +1
Query: 13 RFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILN 192
++A E K P +E TYR HS SD YR+++E+ + +PI +
Sbjct: 268 KYAREQIIKNKEPFFIEFITYRIGDHSTSDHSVLYRSQEEIDSWKSGNNPINRLGLFLKK 327
Query: 193 HEL--VTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
L D I VR V A K + I++L D+Y
Sbjct: 328 QGLRQFNDDHDNQIRKDVRNRVIAALKHGSEQQSPSIQDLFTDVY 372
>UniRef50_Q8YDW3 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=10; Bacteria|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 729
Score = 45.2 bits (102), Expect = 0.001
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 2/80 (2%)
Frame = +1
Query: 37 AGKGPLVMEMETYRYSGHSMSDPGTS--YRTRDEVQEVRQTRDPITSFKEKILNHELVTP 210
AG GP ++E + YRY + PG++ YR++DE E R RDP+ + + +L + +
Sbjct: 269 AGNGPTIIEADVYRYFHQNGPLPGSAFGYRSKDEEAEWR-GRDPLDALAKTLLERQALGE 327
Query: 211 DQLKDIDAKVRKEVDEATKQ 270
D +K + + +DE Q
Sbjct: 328 DAIKALRERCVSLMDEVAGQ 347
>UniRef50_UPI00005103B4 Cluster: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit; n=1; Brevibacterium
linens BL2|Rep: COG1071: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase (E1) component,
eukaryotic type, alpha subunit - Brevibacterium linens
BL2
Length = 368
Score = 44.8 bits (101), Expect = 0.002
Identities = 29/105 (27%), Positives = 44/105 (41%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A A+E G GP ++E TYR H+ SD T YR +EV+ +Q DPI ++ +
Sbjct: 241 AVAAALERGRNGDGPTLIECLTYRMESHTNSDDPTKYRDSEEVEHWKQF-DPIDRLEKYL 299
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ + ++ E EV EL A +Y
Sbjct: 300 RTTGALDDSTVAEVAEAAETLAASVRDAMNQEAEVDPRELFAHVY 344
>UniRef50_A5IXN2 Cluster: Pyruvate dehydrogenase E1 component,
alphasubunit; n=1; Mycoplasma agalactiae|Rep: Pyruvate
dehydrogenase E1 component, alphasubunit - Mycoplasma
agalactiae
Length = 363
Score = 44.8 bits (101), Expect = 0.002
Identities = 24/83 (28%), Positives = 43/83 (51%)
Frame = +1
Query: 28 YCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVT 207
Y G GP+++EM T+R H+ SD YR+R E++ ++ +P + +L+ +L+T
Sbjct: 246 YVREGNGPVLVEMVTWRQGQHTTSDNPRVYRSR-ELEMEKEKWEPFHRIEAYLLSEKLIT 304
Query: 208 PDQLKDIDAKVRKEVDEATKQSK 276
+ +K +E A SK
Sbjct: 305 EEDIKVWSEAAAEEAKAAYALSK 327
>UniRef50_Q295J7 Cluster: GA20891-PA; n=7; Coelomata|Rep: GA20891-PA
- Drosophila pseudoobscura (Fruit fly)
Length = 439
Score = 44.4 bits (100), Expect = 0.002
Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 4/94 (4%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A + A EY P+V E YR HS SD T+YR+ +E++ PI+ K +
Sbjct: 303 AMKEAREYVLRENKPVVFEALAYRVGHHSTSDDSTAYRSTEEIEVWNSVEHPISKLKRYM 362
Query: 187 LN----HELVTPDQLKDIDAKVRKEVDEATKQSK 276
++ E +K++ KV K++ + K+ K
Sbjct: 363 VHKGWFDEAEETAYIKEVRKKVLKQIAVSEKKLK 396
>UniRef50_Q5KGR5 Cluster: Branched-chain alpha-keto acid
dehydrogenase E1-alpha subunit, putative; n=2;
Filobasidiella neoformans|Rep: Branched-chain alpha-keto
acid dehydrogenase E1-alpha subunit, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 504
Score = 44.4 bits (100), Expect = 0.002
Identities = 28/106 (26%), Positives = 57/106 (53%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA + A+E GK +++E TYR HS SD + YR +EV+E +PI +
Sbjct: 348 EARKRAVE----GKKGVLVEAMTYRVGHHSTSDDSSMYRAIEEVKEWSVVDNPIHRLRSY 403
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+++ + + ++ K + K + +V +A +++ P+ + E+ D++
Sbjct: 404 LVSKKWWSEEEEKALLKKNKADVLKAFSRAEKLPKPKLGEMFNDVW 449
>UniRef50_A3RZM3 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=5; Proteobacteria|Rep: Pyruvate dehydrogenase
E1 component alpha subunit - Ralstonia solanacearum
UW551
Length = 368
Score = 44.0 bits (99), Expect = 0.003
Identities = 24/86 (27%), Positives = 43/86 (50%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+AA+ A++ AG GP ++E +YR H+ +D T YR D V++ R+PI +
Sbjct: 232 QAAQEALDKARAGGGPTLIEALSYRLGDHTTADDATRYRDSDIVKQA-WAREPILRLRNY 290
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEA 261
++ Q + + +V+EA
Sbjct: 291 LVRQNAWDKAQEEQLGRACYAQVEEA 316
>UniRef50_Q4L1A7 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=9; Mycoplasma|Rep: Pyruvate dehydrogenase E1
component alpha subunit - Mycoplasma synoviae
Length = 374
Score = 43.6 bits (98), Expect = 0.004
Identities = 27/107 (25%), Positives = 55/107 (51%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A+E+ P+++E T+R H+ SD YRT E +E ++ +P+ ++ +L+ +
Sbjct: 251 AVEFARKESRPVLVEFVTWRQGPHTTSDNPRVYRTETEEKE-QEVWEPMHRIEKYLLDRK 309
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEP 339
L+T +++ I A + + ++S E ++E+ D Y L P
Sbjct: 310 LLTKKEIEKIWADSLEVAKKTYEESVKLNEATLDEV-FDYTYAELTP 355
>UniRef50_Q3W421 Cluster: Pyruvate dehydrogenase; n=1; Frankia sp.
EAN1pec|Rep: Pyruvate dehydrogenase - Frankia sp.
EAN1pec
Length = 358
Score = 43.6 bits (98), Expect = 0.004
Identities = 20/50 (40%), Positives = 32/50 (64%)
Frame = +1
Query: 16 FAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 165
+A+E+ +G+GP+++E TYR + H+ SD + Y+ EV R RDPI
Sbjct: 243 WALEHARSGQGPVLIEANTYRMAPHTTSDDASRYQEAAEVAAWR-ARDPI 291
>UniRef50_Q2S3D2 Cluster: 2-oxoglutarate dehydrogenase, E1 component;
n=3; Bacteria|Rep: 2-oxoglutarate dehydrogenase, E1
component - Salinibacter ruber (strain DSM 13855)
Length = 1243
Score = 43.2 bits (97), Expect = 0.005
Identities = 29/125 (23%), Positives = 55/125 (44%)
Frame = +1
Query: 10 ARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKIL 189
AR A EY +V++M YR GH+ D T + +++ + R P + E +L
Sbjct: 739 ARLAFEYRQRFNKDVVIDMMCYRVHGHNEGDEPT-FTQPLLYEKIEEKRSPRKLYTEMLL 797
Query: 190 NHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVRGIHPAAP 369
+ PD+ + + R + EA +++K E +E + + + + + A
Sbjct: 798 RRGEIEPDEAEQMLDDYRGRLQEAFERTKDLEEKDADEALEERVQRTADDRLPPVDTTAE 857
Query: 370 LKHLE 384
+HLE
Sbjct: 858 REHLE 862
>UniRef50_A6WG12 Cluster: Pyruvate dehydrogenase; n=3;
Actinomycetales|Rep: Pyruvate dehydrogenase -
Kineococcus radiotolerans SRS30216
Length = 390
Score = 43.2 bits (97), Expect = 0.005
Identities = 28/82 (34%), Positives = 41/82 (50%)
Frame = +1
Query: 13 RFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILN 192
R A+E +G GP +E TYR H+ +D T YR E + R+ +DPI F+ L
Sbjct: 254 RAALERARSGGGPTFVEAFTYRMGAHTTADDPTRYRLSAETEAWRE-KDPIDRFR-TYLR 311
Query: 193 HELVTPDQLKDIDAKVRKEVDE 258
E + D + +A + E DE
Sbjct: 312 AEGILDD---EYEAALAAEADE 330
>UniRef50_A3SJ75 Cluster: 2-oxoisovalerate dehydrogenase beta
subunit; n=1; Roseovarius nubinhibens ISM|Rep:
2-oxoisovalerate dehydrogenase beta subunit -
Roseovarius nubinhibens ISM
Length = 746
Score = 43.2 bits (97), Expect = 0.005
Identities = 38/131 (29%), Positives = 62/131 (47%), Gaps = 4/131 (3%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQE-VRQTRDPITSFKE 180
E AR IE GP+++E TYR+ S G+++ RD+ +E RDP T+ +
Sbjct: 276 ETARKIIE---TSGGPVLLEARTYRHLHQSGPLKGSAFGYRDKAEEDAWLARDPATTLPQ 332
Query: 181 KILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY--YKNLEPFVRG- 351
+IL L+T Q+ + ++ VD+ T E L D++ +E +RG
Sbjct: 333 QILRAGLLTEAQIDTLRSRATAAVDD-TLDRLIEGSGKDRRLKPDLWPDPATVEYGIRGD 391
Query: 352 IHPAAPLKHLE 384
+ A +HLE
Sbjct: 392 LSELADKRHLE 402
>UniRef50_A0JY23 Cluster: Pyruvate dehydrogenase; n=2;
Arthrobacter|Rep: Pyruvate dehydrogenase - Arthrobacter
sp. (strain FB24)
Length = 359
Score = 43.2 bits (97), Expect = 0.005
Identities = 22/62 (35%), Positives = 35/62 (56%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+A R A + AG GP+++E TYR HS SD YR+ +E ++ DP+ F++
Sbjct: 234 DATRRAFAHARAGHGPVLIEAMTYRRGPHSTSDDPGRYRSLNEERD-DAGEDPLERFRKT 292
Query: 184 IL 189
+L
Sbjct: 293 LL 294
>UniRef50_Q9YBC0 Cluster: Pyruvate dehydrogenase E1 component, alpha
subunit; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase E1 component, alpha subunit - Aeropyrum
pernix
Length = 377
Score = 43.2 bits (97), Expect = 0.005
Identities = 22/101 (21%), Positives = 50/101 (49%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A E G GP ++E TYR H+ +D + YRT +E + + + +P+ ++ + +
Sbjct: 248 AAEKARRGGGPTLIEAVTYRLGPHTTADDPSRYRTSEE-ERIMERYEPLRRMRKFMESMG 306
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++T + I+ + +V+E ++ +P + ++Y
Sbjct: 307 ILTEKEALSIEEEWNSKVEEIVRKVLAKPPLPENVFFQNVY 347
>UniRef50_Q9HNV6 Cluster: Pyruvate dehydrogenase alpha subunit; n=1;
Halobacterium salinarum|Rep: Pyruvate dehydrogenase
alpha subunit - Halobacterium salinarium (Halobacterium
halobium)
Length = 322
Score = 43.2 bits (97), Expect = 0.005
Identities = 20/91 (21%), Positives = 44/91 (48%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P+++E TYR H+ SD YR +E +T DP+ + + + + ++ +++
Sbjct: 204 PILVESLTYRQGAHTTSDDPDRYRPEEEDLPAWRTADPVDRYADYLHDQGVIDAGFVEEC 263
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
E+D+A + ++ ++EL +Y
Sbjct: 264 FDAAADEIDDAVETAEAAGAPAVDELFDHVY 294
>UniRef50_Q319T4 Cluster: Pyruvate dehydrogenase; n=1;
Prochlorococcus marinus str. MIT 9312|Rep: Pyruvate
dehydrogenase - Prochlorococcus marinus (strain MIT
9312)
Length = 347
Score = 42.7 bits (96), Expect = 0.007
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 4/84 (4%)
Frame = +1
Query: 22 IEYCNAGKGPLVMEMETYRYSGH----SMSDPGTSYRTRDEVQEVRQTRDPITSFKEKIL 189
I C G+GP +E TYR+ GH D G + R+ D+++ ++ RDPI K+ +L
Sbjct: 241 IRRCRDGEGPFFIEALTYRWFGHVDWREDIDVGIN-RSADDLKYWKK-RDPILRLKKSLL 298
Query: 190 NHELVTPDQLKDIDAKVRKEVDEA 261
+ L +++ ++K++D A
Sbjct: 299 KENYFGENHLINLEKDIQKDIDNA 322
>UniRef50_A6UDY5 Cluster: Dehydrogenase E1 component; n=2;
Alphaproteobacteria|Rep: Dehydrogenase E1 component -
Sinorhizobium medicae WSM419
Length = 342
Score = 42.7 bits (96), Expect = 0.007
Identities = 27/105 (25%), Positives = 51/105 (48%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AAR+ ++ AGK P + +E YR+ GH+ D + YR E E R+ +DP+ + K+
Sbjct: 218 AARWLVDEARAGK-PGFLSVEVYRFFGHARMDK-SPYREEAEELEGRK-KDPVLFARNKL 274
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++ + L ++D + E+D + + + D+Y
Sbjct: 275 IDTGIEEERILDELDKAIAAEMDATIDFAVESKAPPLGSMFKDVY 319
>UniRef50_A1UJ85 Cluster: Pyruvate dehydrogenase; n=16;
Mycobacterium|Rep: Pyruvate dehydrogenase -
Mycobacterium sp. (strain KMS)
Length = 356
Score = 42.7 bits (96), Expect = 0.007
Identities = 29/97 (29%), Positives = 48/97 (49%), Gaps = 1/97 (1%)
Frame = +1
Query: 37 AGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQ 216
AG GP ++E TYR H+ SD T YR + EV R RDPI ++ L V ++
Sbjct: 241 AGGGPTLIEAVTYRLGPHTTSDDPTRYRDQSEVDRWR-ARDPIPRYR-TYLQGAGVWSER 298
Query: 217 LKD-IDAKVRKEVDEATKQSKTEPEVGIEELSADIYY 324
L++ + A+ ++ E P+ + E+ +Y+
Sbjct: 299 LEERVAARSKRLRAELRDAVVGAPDFDVSEVFDTVYH 335
>UniRef50_A0K283 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 415
Score = 42.7 bits (96), Expect = 0.007
Identities = 24/66 (36%), Positives = 35/66 (53%)
Frame = +1
Query: 16 FAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNH 195
+A+E GK P+++E TYR H+ +D T YR DE + R +DP+ EK L
Sbjct: 277 WALERAREGKSPVLIEAFTYRVGAHTTADDPTKYRGSDEEAQWR-AKDPLERL-EKYLRA 334
Query: 196 ELVTPD 213
E + D
Sbjct: 335 EGMADD 340
>UniRef50_A3TUC4 Cluster: TPP-dependent acetoin dehydrogenase
complex, E1 component, alpha subunit; n=1; Oceanicola
batsensis HTCC2597|Rep: TPP-dependent acetoin
dehydrogenase complex, E1 component, alpha subunit -
Oceanicola batsensis HTCC2597
Length = 86
Score = 42.3 bits (95), Expect = 0.009
Identities = 23/86 (26%), Positives = 44/86 (51%)
Frame = +1
Query: 64 METYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVR 243
METYR +GH M D YR E + + +DPI + + ++L + ++L I+A+
Sbjct: 1 METYRLAGHFMGD-AEGYRPEGEKDGLFE-KDPIPAMRARLLKDGAASEEELAAIEAEAE 58
Query: 244 KEVDEATKQSKTEPEVGIEELSADIY 321
V++A K ++ + E+ ++
Sbjct: 59 ARVEKAIKFARDSADPAPEDALTAVF 84
>UniRef50_A0M1U4 Cluster: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta; n=18;
Bacteroidetes|Rep: 2-oxoisovalerate dehydrogenase E1
component subunits alpha and beta - Gramella forsetii
(strain KT0803)
Length = 685
Score = 42.3 bits (95), Expect = 0.009
Identities = 24/97 (24%), Positives = 53/97 (54%), Gaps = 1/97 (1%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P+++E +T+R GH + GT Y ++ + E +Q +DP+ +F+E ++ ++T D +
Sbjct: 261 PVLVEFKTFRMRGHEEAS-GTKYVPQELMDEWQQ-KDPVLNFEEYLIAKNILTNDLKEKF 318
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEEL-SADIYYKNLE 336
++ E+D+ + + +E + + D Y+N E
Sbjct: 319 RTEILAEIDKNLQLAFSEDIIVSDATKELDDVYENFE 355
>UniRef50_Q00TN9 Cluster: Pyruvate dehydrogenase E1 component beta;
n=3; Ostreococcus|Rep: Pyruvate dehydrogenase E1
component beta - Ostreococcus tauri
Length = 835
Score = 42.3 bits (95), Expect = 0.009
Identities = 17/45 (37%), Positives = 28/45 (62%)
Frame = +1
Query: 43 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFK 177
KGP ++++ T+R++GHS +DP +DE + R DPI F+
Sbjct: 363 KGPAILQVHTFRFNGHSPADPEHERNRKDEKRWARAECDPIKIFE 407
>UniRef50_Q8YDG0 Cluster: 2-OXOISOVALERATE DEHYDROGENASE BETA
SUBUNIT; n=3; Brucella|Rep: 2-OXOISOVALERATE
DEHYDROGENASE BETA SUBUNIT - Brucella melitensis
Length = 725
Score = 41.9 bits (94), Expect = 0.012
Identities = 30/99 (30%), Positives = 48/99 (48%), Gaps = 2/99 (2%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGT--SYRTRDEVQEVRQTRDPITSFK 177
+A R A GP+V+E + YRY S S G+ YRTR+E +E + +RDPI +
Sbjct: 259 QAMREACRIIEEEGGPVVIEAQCYRYLHQSGSKSGSDFGYRTREEEEEWK-SRDPIALAE 317
Query: 178 EKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVG 294
++ + + +D +V V +A + TE G
Sbjct: 318 RRLKELGIAGDAEFLKLDERVTAAV-QAAGERLTETAAG 355
>UniRef50_Q13GQ3 Cluster: Putative 2-oxo acid dehydrogenase alpha
subunit; n=1; Burkholderia xenovorans LB400|Rep:
Putative 2-oxo acid dehydrogenase alpha subunit -
Burkholderia xenovorans (strain LB400)
Length = 334
Score = 41.9 bits (94), Expect = 0.012
Identities = 29/106 (27%), Positives = 47/106 (44%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA+ A +G GP V+E T+R GH DP YR E+ + +DP+
Sbjct: 225 EASGIAAAAARSGAGPFVLECVTHRVRGHYEGDP-QKYRDPTELDGL-AGKDPLKRMHTH 282
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
L V+ ++ I V V+ A + ++ + +E S D+Y
Sbjct: 283 -LESAGVSASEIDQIGRAVLTRVEAAIEAARADALPDFDEASRDVY 327
>UniRef50_A4XF89 Cluster: Dehydrogenase, E1 component; n=1;
Novosphingobium aromaticivorans DSM 12444|Rep:
Dehydrogenase, E1 component - Novosphingobium
aromaticivorans (strain DSM 12444)
Length = 315
Score = 41.9 bits (94), Expect = 0.012
Identities = 32/107 (29%), Positives = 49/107 (45%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA R A AGKGP ++E + R GH DP YR D +R RDP+ +
Sbjct: 217 EATREAAARARAGKGPTLIEAKVTRKHGHYAGDP-QHYRDPD---YLRDYRDPLDLLAAR 272
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYY 324
+ + V ++ DA EV A + ++ PE + + D+Y+
Sbjct: 273 LAGN--VAARIVEQADA----EVAAAYEAARAAPEPDVSVIERDLYH 313
>UniRef50_P09060 Cluster: 2-oxoisovalerate dehydrogenase subunit
alpha; n=68; Proteobacteria|Rep: 2-oxoisovalerate
dehydrogenase subunit alpha - Pseudomonas putida
Length = 410
Score = 41.5 bits (93), Expect = 0.015
Identities = 26/90 (28%), Positives = 43/90 (47%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A+R+A E G GP ++E TYR HS SD + YR D+ DPI K+ +
Sbjct: 285 ASRWAAERARRGLGPSLIEWVTYRAGPHSTSDDPSKYRPADDWSHF-PLGDPIARLKQHL 343
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSK 276
+ + ++ + A+ V A K+++
Sbjct: 344 IKIGHWSEEEHQATTAEFEAAVIAAQKEAE 373
>UniRef50_Q1IY28 Cluster: Pyruvate dehydrogenase; n=1; Deinococcus
geothermalis DSM 11300|Rep: Pyruvate dehydrogenase -
Deinococcus geothermalis (strain DSM 11300)
Length = 361
Score = 41.1 bits (92), Expect = 0.020
Identities = 25/110 (22%), Positives = 50/110 (45%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A+ G+GP ++E TYR H+++D + YR+ D +DP+ + +L
Sbjct: 242 AVNRARNGEGPTLIETVTYRVKPHTVADDPSRYRS-DADTAGWDAKDPVRRLQTHLLTEG 300
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVR 348
+T + +I ++ E + A + + PE E+ ++ + VR
Sbjct: 301 HLTEKEDAEITREIEAEFEAALQVADRFPEPTPAEIVDHVFAEPTPQLVR 350
>UniRef50_Q11G20 Cluster: Twin-arginine translocation pathway
signal; n=2; Proteobacteria|Rep: Twin-arginine
translocation pathway signal - Mesorhizobium sp. (strain
BNC1)
Length = 375
Score = 41.1 bits (92), Expect = 0.020
Identities = 29/108 (26%), Positives = 56/108 (51%), Gaps = 15/108 (13%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGH---SMSDPG------------TSYRTRDEVQE 141
AA+ A++ AG+GP ++E +TYRY H + PG +S+R E++
Sbjct: 246 AAKTAVDRARAGEGPTLIEAKTYRYYNHWGAPGAKPGELGAFGYDPLAISSFRPERELRS 305
Query: 142 VRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEP 285
Q RDP+ + ++N ++ + +I+A V+++V +A + +P
Sbjct: 306 WMQ-RDPVRIAHDILVNWGVIDHAKAAEIEASVKQDVADAFAWAAEQP 352
>UniRef50_Q4P2J0 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 786
Score = 41.1 bits (92), Expect = 0.020
Identities = 22/91 (24%), Positives = 45/91 (49%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P+++E TYR HS SD ++YR++ V+ +Q +P+ + + + + ++
Sbjct: 648 PVLIEAMTYRVGHHSTSDDSSAYRSKQAVESWKQMDNPLHRMRNYLTDRGWWNDELEEET 707
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
A RK+V EA +++ + + L Y
Sbjct: 708 KAGHRKKVIEAMARAEKKKRPKLSSLFEGTY 738
>UniRef50_Q023C4 Cluster: Pyruvate dehydrogenase; n=1; Solibacter
usitatus Ellin6076|Rep: Pyruvate dehydrogenase -
Solibacter usitatus (strain Ellin6076)
Length = 397
Score = 40.3 bits (90), Expect = 0.036
Identities = 15/57 (26%), Positives = 33/57 (57%)
Frame = +1
Query: 175 KEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFV 345
K+ ++ + ++TPD+++ A ++ EVD+A ++ + P+ L A IY + P +
Sbjct: 6 KDTLIRNRVLTPDEVEAFRASIKSEVDQAAAEADSHPQPATSNLLAHIYSERTAPAI 62
>UniRef50_A0JUQ5 Cluster: Pyruvate dehydrogenase; n=4;
Actinobacteria (class)|Rep: Pyruvate dehydrogenase -
Arthrobacter sp. (strain FB24)
Length = 392
Score = 40.3 bits (90), Expect = 0.036
Identities = 24/72 (33%), Positives = 38/72 (52%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A R A+E G GP +E TYR H+ +D T YR +E+++ +DPI + +
Sbjct: 255 ATREALERARHGGGPTFIEAVTYRMGPHTTADDPTRYRDANELED-WAAKDPIARVRGLL 313
Query: 187 LNHELVTPDQLK 222
L+T D+L+
Sbjct: 314 ERKGLLT-DELE 324
>UniRef50_Q95VS6 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=2; Antonospora locustae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Antonospora locustae (Nosema locustae)
Length = 342
Score = 40.3 bits (90), Expect = 0.036
Identities = 27/84 (32%), Positives = 45/84 (53%), Gaps = 3/84 (3%)
Frame = +1
Query: 43 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNH---ELVTPD 213
KGPL+++++TYR GHS +D G YR EV+ R+ R+ + + ++ E +
Sbjct: 252 KGPLIVQIDTYRLCGHSTTD-GIVYRDETEVRRERE-RNALGHTESALVQRFGAEHIAAI 309
Query: 214 QLKDIDAKVRKEVDEATKQSKTEP 285
+ D+ + V EVD A + EP
Sbjct: 310 K-ADVRSHVAHEVDVALAMLEPEP 332
>UniRef50_Q8D6Q7 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dehydrogenase component, eukaryotic type, alpha
subunit; n=4; Vibrionaceae|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dehydrogenase component,
eukaryotic type, alpha subunit - Vibrio vulnificus
Length = 364
Score = 39.9 bits (89), Expect = 0.047
Identities = 27/110 (24%), Positives = 53/110 (48%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+A A++ GKG ++E +YR S H+ +D + YR+ DE+++ Q +PI +
Sbjct: 233 DAVNNALDRARKGKGATLIEAISYRLSDHTTADDASRYRSADELKQAWQ-YEPIKRLQAY 291
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNL 333
+ L + + A +++V++A + P E + D Y +L
Sbjct: 292 LTAQGLWNEELEQQWLAHCKQQVEQAVAHYLSLPPQA-PESAFDYLYASL 340
>UniRef50_A0HHH5 Cluster: Dehydrogenase, E1 component; n=2;
Bacteria|Rep: Dehydrogenase, E1 component - Comamonas
testosteroni KF-1
Length = 327
Score = 39.9 bits (89), Expect = 0.047
Identities = 25/94 (26%), Positives = 46/94 (48%)
Frame = +1
Query: 40 GKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQL 219
G GP+++EM T R GH + D SYRT E+ E + +PI ++ L V+ ++
Sbjct: 235 GHGPVLIEMMTQRLVGHYIGDM-QSYRTAREIAEAK-LHEPIVRLGQR-LQLSGVSDAEV 291
Query: 220 KDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++I ++ AT ++ P + + +Y
Sbjct: 292 QNIHLNAAAHIEAATAKALNAPLASADTVMEHLY 325
>UniRef50_Q5VGY4 Cluster: Pyruvate dehydrogenase alpha subunit; n=6;
Plasmodium|Rep: Pyruvate dehydrogenase alpha subunit -
Plasmodium falciparum
Length = 608
Score = 39.9 bits (89), Expect = 0.047
Identities = 22/87 (25%), Positives = 41/87 (47%)
Frame = +1
Query: 34 NAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPD 213
N GP+++E TYR GHS++DP R ++E ++ RDPI + + LV
Sbjct: 448 NRTSGPIIIEAITYRAKGHSLADP-DELRIKEEKTSWKK-RDPILFLSSYMKKYNLVQES 505
Query: 214 QLKDIDAKVRKEVDEATKQSKTEPEVG 294
+ + + + +A ++ + G
Sbjct: 506 YFEQVKKNTQTLLQQAELDAEQNTKKG 532
>UniRef50_Q8PQ82 Cluster: Pyruvate dehydrogenase E1 alpha subunit;
n=7; Xanthomonadaceae|Rep: Pyruvate dehydrogenase E1
alpha subunit - Xanthomonas axonopodis pv. citri
Length = 362
Score = 39.5 bits (88), Expect = 0.062
Identities = 30/106 (28%), Positives = 44/106 (41%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA R A AG+G V+E TYR S H+ +D YR +EV++ R+P+ +
Sbjct: 236 EAMRQARVRALAGEGGTVIEFLTYRLSDHTTADDARRYRGEEEVKQ-GWAREPLLRLRRY 294
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ L Q A VDE P +E + +Y
Sbjct: 295 LTAQGLWDEAQEDAWKADCSARVDEEVNAYLNTPVQPVEAMFDYLY 340
>UniRef50_Q83FF2 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Tropheryma whipplei|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Tropheryma
whipplei (strain Twist) (Whipple's bacillus)
Length = 370
Score = 39.5 bits (88), Expect = 0.062
Identities = 17/40 (42%), Positives = 25/40 (62%)
Frame = +1
Query: 22 IEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQE 141
++ +GKGP ++E TYR H+ SD T YR+ DE +E
Sbjct: 252 MDRARSGKGPHLIEAFTYRLGAHTTSDDPTRYRSEDEHRE 291
>UniRef50_Q0MX87 Cluster: Acetoin dehydrogenase alpha-subunit; n=2;
Bacteria|Rep: Acetoin dehydrogenase alpha-subunit -
consortium cosmid clone pGZ1
Length = 344
Score = 39.5 bits (88), Expect = 0.062
Identities = 27/85 (31%), Positives = 43/85 (50%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AAR A+ AG+GP ++ +TYR++GH DP +YR E+ + DP+ + +
Sbjct: 234 AARDAVASVRAGEGPRLLHAKTYRFTGHVSVDP-AAYRDPGELAAAMED-DPLLVARVR- 290
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEA 261
L V D ++ R+EV A
Sbjct: 291 LQASGVAGDAVEAAMRAAREEVAAA 315
>UniRef50_A5V540 Cluster: Dehydrogenase, E1 component; n=3;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Sphingomonas wittichii RW1
Length = 334
Score = 39.5 bits (88), Expect = 0.062
Identities = 28/106 (26%), Positives = 51/106 (48%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E A ++ +GP V+E T R GH D YR +D+ V DP+ + +
Sbjct: 229 ELAADVVDRVRRDRGPAVLEFATTRIRGHYEGD-AQRYR-QDKAPPV----DPLLVARAR 282
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
L+ V +++ I+A +R EV A + ++ P+ +E + ++Y
Sbjct: 283 -LDERGVPAAEVEAIEADIRAEVRRAVEAARLSPDPTLESAAEEVY 327
>UniRef50_Q6L1L8 Cluster: Pyruvate dehydrogenase E1 component alpha
subunit; n=2; Thermoplasmatales|Rep: Pyruvate
dehydrogenase E1 component alpha subunit - Picrophilus
torridus
Length = 333
Score = 39.5 bits (88), Expect = 0.062
Identities = 25/105 (23%), Positives = 52/105 (49%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
A R AI+ K PL+++ TYR H+ +D YR + + E DP++ ++ I
Sbjct: 216 AIRNAIKDVEKNKMPLLIDAVTYRMGPHTTADDPNKYR-KTIINE-GDPLDPLSIIEDDI 273
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+++ +++ +I ++ V + ++ + + G E L +IY
Sbjct: 274 KKMKILNDEEISNIKNEINNMVSKEVERYEKMNKPGKETLFKNIY 318
>UniRef50_Q479Q2 Cluster: Dehydrogenase, E1 component; n=2;
Rhodocyclaceae|Rep: Dehydrogenase, E1 component -
Dechloromonas aromatica (strain RCB)
Length = 320
Score = 39.1 bits (87), Expect = 0.082
Identities = 31/108 (28%), Positives = 50/108 (46%), Gaps = 2/108 (1%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
EA R A + P+++E+ TYR GH D Y + E+ RDPI +++
Sbjct: 216 EATREAATQVRDTRRPVLLEVLTYRTRGHFEPD-DQGYVDKAEL-AAWLARDPIALCRDR 273
Query: 184 IL--NHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
++ H V D ++ A+V + A + P IEEL+ D+Y
Sbjct: 274 LIADGHLDVAAD--AELAARVEASIAAAVAFAAASPFPSIEELTLDVY 319
>UniRef50_A4CGF1 Cluster: 2-oxoglutarate dehydrogenase, E1
component; n=16; cellular organisms|Rep: 2-oxoglutarate
dehydrogenase, E1 component - Robiginitalea biformata
HTCC2501
Length = 940
Score = 39.1 bits (87), Expect = 0.082
Identities = 22/103 (21%), Positives = 51/103 (49%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AA FA+EY + + +++ YR GH+ D + + + + ++P + E++
Sbjct: 422 AALFALEYRMKFRRDVFLDLLGYRKYGHNEGDE-PRFTQPKLYKAIAKHQNPRDIYAERL 480
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSAD 315
++ ++ D +K ++ + +++E + SK E + I AD
Sbjct: 481 MSEGVIDADFVKKLEEDYKAKLEEELRDSKKEDKTRITAFMAD 523
>UniRef50_Q4N1L6 Cluster: Branched-chain alpha keto-acid
dehydrogenase, putative; n=3; Piroplasmida|Rep:
Branched-chain alpha keto-acid dehydrogenase, putative -
Theileria parva
Length = 464
Score = 39.1 bits (87), Expect = 0.082
Identities = 17/44 (38%), Positives = 24/44 (54%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQ 138
A ++ EYC P+V+E TYR HS SD + YR + E +
Sbjct: 323 ATKYCREYCVKHSTPIVIEYMTYRIGHHSTSDESSQYRGKGEFE 366
>UniRef50_A7RZV6 Cluster: Predicted protein; n=6; Eumetazoa|Rep:
Predicted protein - Nematostella vectensis
Length = 444
Score = 39.1 bits (87), Expect = 0.082
Identities = 26/100 (26%), Positives = 48/100 (48%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P+++E TYR HS SD + YR+ EV + PI+ + + + DQ +
Sbjct: 321 PVLVEAMTYRIGHHSTSDDSSVYRSLKEVNYWDKEDHPISRLRYYMEDKGWWDQDQEQQW 380
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVR 348
+ R +V +A ++ + ++EL D+ YK P ++
Sbjct: 381 KKEARLQVMQAFADAEKALKPPVKELFLDV-YKEFTPHLQ 419
>UniRef50_A3PXW7 Cluster: Transketolase domain protein; n=4;
Mycobacterium|Rep: Transketolase domain protein -
Mycobacterium sp. (strain JLS)
Length = 721
Score = 38.7 bits (86), Expect = 0.11
Identities = 22/96 (22%), Positives = 44/96 (45%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E R A E+ + P + + T R GH+ SD YR DE+ RDP+ +
Sbjct: 258 ETTRAAAEFVRTHRRPAFLHLSTVRLMGHAGSDYEPGYRRPDEI-VADFDRDPVLCAAKA 316
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEV 291
++ +++P ++ + R++V + + P++
Sbjct: 317 LVAQGILSPVEVLERYEATRRQVLDMAAEVMDAPQL 352
>UniRef50_O17231 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 286
Score = 38.7 bits (86), Expect = 0.11
Identities = 23/75 (30%), Positives = 38/75 (50%), Gaps = 3/75 (4%)
Frame = +1
Query: 187 LNH--ELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYK-NLEPFVRGIH 357
LNH +++P + V E DEA +S +E E + +Y+K ++PF + I+
Sbjct: 102 LNHFLSIISPSNIDLFHFPVYNEFDEAQFKSLSECLESHEIYNLHVYWKFEMDPFFKVIN 161
Query: 358 PAAPLKHLEVQPRNH 402
P KHL++ P H
Sbjct: 162 AFLPTKHLKIHPTFH 176
>UniRef50_Q93N50 Cluster: Pyruvate dehydrogenase alpha subunit; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase alpha subunit
- Coxiella burnetii
Length = 341
Score = 37.9 bits (84), Expect = 0.19
Identities = 21/84 (25%), Positives = 45/84 (53%), Gaps = 1/84 (1%)
Frame = +1
Query: 37 AGKGPLVMEMETYRYSGHSMSDPGT-SYRTRDEVQEVRQTRDPITSFKEKILNHELVTPD 213
A G +E +TYR+ H + T + R++ E RDP++ + ++L + V+P+
Sbjct: 226 ANGGVWFLEFQTYRFKVHCGPEEETFTDRSKTEFDHWL-ARDPLSLLQSQLLTAKTVSPE 284
Query: 214 QLKDIDAKVRKEVDEATKQSKTEP 285
++ +++ E+DEA +++ P
Sbjct: 285 EIDKWRHEIQNEIDEAFTFAESSP 308
>UniRef50_Q83DQ6 Cluster: Dehydrogenase, E1 component, alpha
subunit; n=3; Coxiella burnetii|Rep: Dehydrogenase, E1
component, alpha subunit - Coxiella burnetii
Length = 368
Score = 37.9 bits (84), Expect = 0.19
Identities = 22/89 (24%), Positives = 45/89 (50%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A+E G GP ++E +YR H+ +D T Y ++E +V ++PI + +
Sbjct: 242 ALEKARDGGGPTLIEALSYRLCDHTTADDATRYIPQEE-WKVAWQKEPIARLGYYLESQG 300
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEP 285
L + ++ + ++ +EVD+ ++ T P
Sbjct: 301 LWSREKEAVLQKELAQEVDQVVEEFLTMP 329
>UniRef50_Q5LVW0 Cluster: Dehydrogenase/transketolase family
protein; n=23; Proteobacteria|Rep:
Dehydrogenase/transketolase family protein -
Silicibacter pomeroyi
Length = 740
Score = 37.9 bits (84), Expect = 0.19
Identities = 22/94 (23%), Positives = 42/94 (44%)
Frame = +1
Query: 10 ARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKIL 189
A+ A +Y + P + ++T R GH+ +D T+Y TR EV E + DP+ +
Sbjct: 269 AQEAADYVRNRRKPAFLHLKTVRLYGHAGADVPTTYLTRAEV-EAEEAMDPLLHSVRLLA 327
Query: 190 NHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEV 291
+ ++ I + +D ++ T P +
Sbjct: 328 EDGALASEEALAIYEQTCARIDRIAVEAATRPHL 361
>UniRef50_Q83X26 Cluster: Probable pyruvate dehydrogenase
alpha-subunit; n=1; Streptomyces rochei|Rep: Probable
pyruvate dehydrogenase alpha-subunit - Streptomyces
rochei (Streptomyces parvullus)
Length = 326
Score = 37.9 bits (84), Expect = 0.19
Identities = 28/107 (26%), Positives = 47/107 (43%), Gaps = 2/107 (1%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMS--DPGTSYRTRDEVQEVRQTRDPITSFKE 180
AA A+E+C +G GP +E++TYR+ H D R DEV + R PI +
Sbjct: 213 AAVTAVEHCRSGTGPYFLELDTYRWREHVGPGWDHECGARRPDEVLSWTK-RCPIRRAAD 271
Query: 181 KILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+ + + + + + R E A ++ P +E+L Y
Sbjct: 272 ALRGADPDVDEWITAWEREFRAETHAAIAAAEAAPFPRVEDLLVGTY 318
>UniRef50_A5V557 Cluster: Pyruvate dehydrogenase; n=1; Sphingomonas
wittichii RW1|Rep: Pyruvate dehydrogenase - Sphingomonas
wittichii RW1
Length = 331
Score = 37.9 bits (84), Expect = 0.19
Identities = 27/105 (25%), Positives = 49/105 (46%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHE 198
A+ G GP ++E +TYRY+ H+++ EV E R+ RDP+ ++ K++
Sbjct: 221 AVGRARTGGGPTLVETKTYRYADHAVNMGRVLLDRGGEVDEWRK-RDPLALYRAKLIAGG 279
Query: 199 LVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIYYKNL 333
L I+ +V EV +A + ++ E D++ L
Sbjct: 280 TAAA-LLDAIEREVADEVADALQFARDSAWPEQAEAFDDVFVDRL 323
>UniRef50_Q07075 Cluster: Glutamyl aminopeptidase; n=30;
Euteleostomi|Rep: Glutamyl aminopeptidase - Homo sapiens
(Human)
Length = 957
Score = 37.5 bits (83), Expect = 0.25
Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 3/67 (4%)
Frame = -2
Query: 309 GQLFNTDFWFRLRLFSGLVYFFTYLGVDILELIW--RDELVIQDLL-LERSDGVSGLPHL 139
G + D+W L L G FF +LGV+ E W RD+++++D+L ++ D + +
Sbjct: 401 GNIVTMDWWEDLWLNEGFASFFEFLGVNHAETDWQMRDQMLLEDVLPVQEDDSLMSSHPI 460
Query: 138 LHLVSRP 118
+ V+ P
Sbjct: 461 IVTVTTP 467
>UniRef50_Q9Z9E8 Cluster: (Pyruvate) Oxoisovalerate Dehydrogenase
Alpha/Beta Fusion ((Pyruvate) oxoisovalerate
dehydrogenase alpha and beta fusion); n=7;
Chlamydiaceae|Rep: (Pyruvate) Oxoisovalerate
Dehydrogenase Alpha/Beta Fusion ((Pyruvate)
oxoisovalerate dehydrogenase alpha and beta fusion) -
Chlamydia pneumoniae (Chlamydophila pneumoniae)
Length = 678
Score = 37.1 bits (82), Expect = 0.33
Identities = 20/94 (21%), Positives = 51/94 (54%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
E A++ P ++ ++ R S HS SD YR+ ++ ++ +DP+ +++
Sbjct: 222 ETFSHAVDQARQHSVPALILIDVVRLSSHSNSDNQEKYRSALDL-KLSMDKDPLILLEKE 280
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEP 285
+N ++P ++++I A+ ++EV ++ + ++ P
Sbjct: 281 AINVFGLSPFEIEEIKAEAQEEVRKSCEIAEALP 314
>UniRef50_A1SN84 Cluster: Pyruvate dehydrogenase; n=12;
Bacteria|Rep: Pyruvate dehydrogenase - Nocardioides sp.
(strain BAA-499 / JS614)
Length = 344
Score = 37.1 bits (82), Expect = 0.33
Identities = 23/94 (24%), Positives = 47/94 (50%)
Frame = +1
Query: 4 EAARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEK 183
+AAR A+ AG+GP ++E+ T R GH D YR ++++ + DPI ++ +
Sbjct: 242 DAARRAVARARAGEGPSLIEVHTLRLWGHFEGD-AQGYRL--DLEDA-PSHDPIPRYETR 297
Query: 184 ILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEP 285
+ ++ + + I + + ++A +K P
Sbjct: 298 LREAGVLDDETVTRIRSAASERTEDAIAFAKNSP 331
>UniRef50_Q28MR4 Cluster: Dehydrogenase E1 component; n=8;
Bacteria|Rep: Dehydrogenase E1 component - Jannaschia
sp. (strain CCS1)
Length = 675
Score = 36.7 bits (81), Expect = 0.44
Identities = 21/84 (25%), Positives = 43/84 (51%)
Frame = +1
Query: 37 AGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQ 216
AG GP ++E TYR+ HSM +YR+ E +E +++DPI + + +
Sbjct: 241 AGDGPTLIEALTYRWDDHSMRANLPAYRSEAE-EEAWKSQDPIVRLEADMSKLGELDAAS 299
Query: 217 LKDIDAKVRKEVDEATKQSKTEPE 288
++ + +V+ A + ++++ E
Sbjct: 300 YAALNDEAEADVEAAIEWARSQAE 323
>UniRef50_Q6CLM5 Cluster: DNA polymerase epsilon subunit C; n=1;
Kluyveromyces lactis|Rep: DNA polymerase epsilon subunit
C - Kluyveromyces lactis (Yeast) (Candida sphaerica)
Length = 166
Score = 36.7 bits (81), Expect = 0.44
Identities = 26/84 (30%), Positives = 41/84 (48%), Gaps = 4/84 (4%)
Frame = +1
Query: 100 DPGTSYRTRDEVQ----EVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATK 267
D T+ R D+ Q V QT + + +E + + +V P +ID + EVDEA +
Sbjct: 71 DLSTAIRNLDKFQFLSDVVPQTENLASLVRENKVRYTIVNPSP--EIDIESEDEVDEANE 128
Query: 268 QSKTEPEVGIEELSADIYYKNLEP 339
EPEV E+ A++ + EP
Sbjct: 129 PEVGEPEVDEAEVEAEVEAEAAEP 152
>UniRef50_A7PGG3 Cluster: Chromosome chr17 scaffold_16, whole genome
shotgun sequence; n=1; Vitis vinifera|Rep: Chromosome
chr17 scaffold_16, whole genome shotgun sequence - Vitis
vinifera (Grape)
Length = 300
Score = 35.9 bits (79), Expect = 0.77
Identities = 18/43 (41%), Positives = 26/43 (60%)
Frame = +1
Query: 43 KGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITS 171
K LV MET SG+ SDPG S R ++Q+ R+ ++P +S
Sbjct: 41 KHDLVNPMETECNSGYGFSDPGVSPRVTADLQQNRENKNPNSS 83
>UniRef50_Q4SZR6 Cluster: Chromosome undetermined SCAF11537, whole
genome shotgun sequence; n=1; Tetraodon
nigroviridis|Rep: Chromosome undetermined SCAF11537,
whole genome shotgun sequence - Tetraodon nigroviridis
(Green puffer)
Length = 501
Score = 35.5 bits (78), Expect = 1.0
Identities = 18/46 (39%), Positives = 25/46 (54%), Gaps = 2/46 (4%)
Frame = -2
Query: 309 GQLFNTDFWFRLRLFSGLVYFFTYLGVDILELIW--RDELVIQDLL 178
G + D+W L L G FF Y+GV+ E W RD ++I D+L
Sbjct: 185 GNIVTMDWWDDLWLNEGFASFFEYVGVEEAEKDWEMRDIMIIDDVL 230
>UniRef50_Q1LFS5 Cluster: Dehydrogenase, E1 component; n=22;
Proteobacteria|Rep: Dehydrogenase, E1 component -
Ralstonia metallidurans (strain CH34 / ATCC 43123 / DSM
2839)
Length = 367
Score = 35.5 bits (78), Expect = 1.0
Identities = 17/54 (31%), Positives = 29/54 (53%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKE 180
AIE+ G GP ++E +YR H+ +D + YR V+E + +PI ++
Sbjct: 237 AIEHARHGGGPTLIEAVSYRLGDHTTADDASRYRDEASVKEAWRC-EPIIRLRD 289
>UniRef50_Q6FXJ5 Cluster: Similar to sp|P12351 Saccharomyces
cerevisiae YLR256w HAP1 transcription factor; n=1;
Candida glabrata|Rep: Similar to sp|P12351 Saccharomyces
cerevisiae YLR256w HAP1 transcription factor - Candida
glabrata (Yeast) (Torulopsis glabrata)
Length = 1355
Score = 35.5 bits (78), Expect = 1.0
Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Frame = -1
Query: 127 LSSDTTCRGPTSNDQSNGT-SPSPSPKDLSLRCSTRWRTW 11
L++D T GP SN NG+ +PS SPKD ++ TW
Sbjct: 585 LTTDNTRSGPPSNSNRNGSETPSVSPKDTNVSIERAKHTW 624
>UniRef50_Q8YJE4 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=97; Bacteria|Rep: 2-oxoglutarate dehydrogenase E1
component - Brucella melitensis
Length = 1004
Score = 35.5 bits (78), Expect = 1.0
Identities = 22/83 (26%), Positives = 42/83 (50%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AA+ A E+ P+V++M YR GH+ D S+ + +R + + + EK+
Sbjct: 488 AAKVATEFRMTFHKPVVIDMFCYRRFGHNEGDE-PSFTQPLMYKAIRAHKTTVQLYGEKL 546
Query: 187 LNHELVTPDQLKDIDAKVRKEVD 255
+ LVT D + + A R++++
Sbjct: 547 IAEGLVTQDDIDRMKADWRQKLE 569
>UniRef50_Q7VR91 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=2; Candidatus Blochmannia|Rep: 2-oxoglutarate
dehydrogenase E1 component - Blochmannia floridanus
Length = 970
Score = 35.1 bits (77), Expect = 1.3
Identities = 19/82 (23%), Positives = 43/82 (52%), Gaps = 1/82 (1%)
Frame = +1
Query: 13 RFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEV-QEVRQTRDPITSFKEKIL 189
RFA+ + N K +V+++ YR GH+ +D + T+ + Q++R + + +K++
Sbjct: 462 RFALNFRNKFKHDIVIDLVCYRRHGHNETD--EPHVTQPMMYQKIRNHPTVLELYAQKLI 519
Query: 190 NHELVTPDQLKDIDAKVRKEVD 255
++ D +K+ R ++D
Sbjct: 520 QKNIINVDDIKNESCLYRSKLD 541
>UniRef50_Q3W7K0 Cluster: Cytochrome P450; n=5; Frankia sp.
EAN1pec|Rep: Cytochrome P450 - Frankia sp. EAN1pec
Length = 544
Score = 35.1 bits (77), Expect = 1.3
Identities = 18/50 (36%), Positives = 25/50 (50%)
Frame = -1
Query: 151 SASPPAPRLSSDTTCRGPTSNDQSNGTSPSPSPKDLSLRCSTRWRTWPPP 2
+AS P+ R ++ + PT S SPS + + S R TR R W PP
Sbjct: 43 TASYPSTRTAASSPRAAPTGTGSSTRRSPSFATRPASGRSPTRGRPWSPP 92
>UniRef50_A4XKW2 Cluster: Putative uncharacterized protein; n=1;
Caldicellulosiruptor saccharolyticus DSM 8903|Rep:
Putative uncharacterized protein - Caldicellulosiruptor
saccharolyticus (strain ATCC 43494 / DSM 8903)
Length = 196
Score = 35.1 bits (77), Expect = 1.3
Identities = 18/61 (29%), Positives = 29/61 (47%)
Frame = +1
Query: 139 EVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADI 318
E ++ + + KE ILNH L Q + K+++ VDE E E+ + +L D
Sbjct: 95 EYSKSLEELEKIKEDILNHILYIKKQKEKTIKKLKETVDEIESLLNNEEELSLRKLQRDF 154
Query: 319 Y 321
Y
Sbjct: 155 Y 155
>UniRef50_Q98RS9 Cluster: Putative uncharacterized protein orf665;
n=1; Guillardia theta|Rep: Putative uncharacterized
protein orf665 - Guillardia theta (Cryptomonas phi)
Length = 665
Score = 34.7 bits (76), Expect = 1.8
Identities = 20/46 (43%), Positives = 26/46 (56%)
Frame = -1
Query: 601 LLFTIVMFTLPKSKVTYCVAVTKINNFYQRYCHINATVKKNNKSVN 464
L+F + F KSK +VT N+FYQ+ CHI +KK NK N
Sbjct: 507 LIFKLTQFYF-KSKKISLFSVTN-NDFYQKLCHIICFLKKPNKISN 550
>UniRef50_Q23GD0 Cluster: Putative uncharacterized protein; n=1;
Tetrahymena thermophila SB210|Rep: Putative
uncharacterized protein - Tetrahymena thermophila SB210
Length = 216
Score = 34.7 bits (76), Expect = 1.8
Identities = 22/76 (28%), Positives = 38/76 (50%)
Frame = +1
Query: 136 QEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSAD 315
++V Q RD + F++K +L+ DQ+ D A+ KEV Q K + +E+ S +
Sbjct: 102 EQVWQRRDRLERFQKKQTIEQLLKVDQVNDEKAQALKEV----IQKKNLESLSLEQNSPE 157
Query: 316 IYYKNLEPFVRGIHPA 363
Y N+ F+ P+
Sbjct: 158 TYIANIIKFIETYLPS 173
>UniRef50_Q8Y8C3 Cluster: Lmo0985 protein; n=11; Listeria
monocytogenes|Rep: Lmo0985 protein - Listeria
monocytogenes
Length = 142
Score = 34.3 bits (75), Expect = 2.3
Identities = 15/44 (34%), Positives = 23/44 (52%)
Frame = -2
Query: 339 GFQVLVVYIGGQLFNTDFWFRLRLFSGLVYFFTYLGVDILELIW 208
GF ++ +I FN +L +S L+ FF ++G IL L W
Sbjct: 46 GFSIVTTFIQQLFFNNSVKTKLAFYSRLIAFFLFIGAAILGLGW 89
>UniRef50_A6DD58 Cluster: Transcription-repair coupling factor; n=1;
Caminibacter mediatlanticus TB-2|Rep:
Transcription-repair coupling factor - Caminibacter
mediatlanticus TB-2
Length = 981
Score = 34.3 bits (75), Expect = 2.3
Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 9/91 (9%)
Frame = +1
Query: 127 DEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRK---EVDEATKQSKT------ 279
D +E+ + ++ F E +LN E++ + KDI K+ K ++++ KT
Sbjct: 231 DLSEEINEYKEFYKEFNEAVLNKEIIPNGKCKDIKWKIEKGKIKIEDEVYDEKTPLEIVA 290
Query: 280 EPEVGIEELSADIYYKNLEPFVRGIHPAAPL 372
+ EV + E D + K P VR I +A L
Sbjct: 291 KNEVLLREYELDDFVKFKRPLVRWIKNSAYL 321
>UniRef50_P38147 Cluster: Serine/threonine-protein kinase CHK1; n=5;
Saccharomycetales|Rep: Serine/threonine-protein kinase
CHK1 - Saccharomyces cerevisiae (Baker's yeast)
Length = 527
Score = 34.3 bits (75), Expect = 2.3
Identities = 20/72 (27%), Positives = 33/72 (45%), Gaps = 8/72 (11%)
Frame = +1
Query: 208 PDQLKDIDAKVRKE--------VDEATKQSKTEPEVGIEELSADIYYKNLEPFVRGIHPA 363
P+ L+ ID V KE D K EP+VG++ A Y++ L + +H
Sbjct: 76 PNVLRLIDCNVSKEYMWIILEMADGGDLFDKIEPDVGVDSDVAQFYFQQLVSAINYLHVE 135
Query: 364 APLKHLEVQPRN 399
+ H +++P N
Sbjct: 136 CGVAHRDIKPEN 147
>UniRef50_UPI00015C4945 Cluster: hypothetical protein CCC13826_0953;
n=1; Campylobacter concisus 13826|Rep: hypothetical
protein CCC13826_0953 - Campylobacter concisus 13826
Length = 542
Score = 33.9 bits (74), Expect = 3.1
Identities = 18/78 (23%), Positives = 45/78 (57%), Gaps = 2/78 (2%)
Frame = +1
Query: 130 EVQEVRQTRDPITSFKEKILNHELVTPDQL--KDIDAKVRKEVDEATKQSKTEPEVGIEE 303
E++ + QT+D + +KEKI++ E + P +L +D +++ + K+ E+ E
Sbjct: 185 ELKPISQTKDVKSLYKEKIISGE-IDPSELSFEDFKEQLKPDPKALYKEKIASGEIDPTE 243
Query: 304 LSADIYYKNLEPFVRGIH 357
+S + + ++L+P ++ ++
Sbjct: 244 ISFEEFKQSLKPDLKALY 261
>UniRef50_UPI0000D56C7C Cluster: PREDICTED: similar to CG14039-PE,
isoform E; n=1; Tribolium castaneum|Rep: PREDICTED:
similar to CG14039-PE, isoform E - Tribolium castaneum
Length = 492
Score = 33.9 bits (74), Expect = 3.1
Identities = 25/87 (28%), Positives = 45/87 (51%)
Frame = +1
Query: 64 METYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVR 243
+E YR GH ++ + V E+ + S E +L VT ++L++I A R
Sbjct: 378 LEMYR-QGHEAAN----LERENRVMEIAKQGPSRISVPE-LLEELQVTKNELENIKAMYR 431
Query: 244 KEVDEATKQSKTEPEVGIEELSADIYY 324
+ + EA +SK +PE+ ++ L + +YY
Sbjct: 432 QLI-EAKNKSKIDPEITLQFLKSAVYY 457
>UniRef50_A1GCL6 Cluster: Transketolase-like; n=2; Salinispora|Rep:
Transketolase-like - Salinispora arenicola CNS205
Length = 805
Score = 33.9 bits (74), Expect = 3.1
Identities = 16/49 (32%), Positives = 26/49 (53%)
Frame = +1
Query: 19 AIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPI 165
A+ + + P V+ + T R GH+ +D T+YRT E+ RDP+
Sbjct: 324 AVRWVRRHRRPAVLHLSTVRLMGHAGADAETAYRTTTEI-AADLDRDPL 371
>UniRef50_Q2H9L8 Cluster: Putative uncharacterized protein; n=2;
Sordariomycetes|Rep: Putative uncharacterized protein -
Chaetomium globosum (Soil fungus)
Length = 472
Score = 33.9 bits (74), Expect = 3.1
Identities = 26/93 (27%), Positives = 45/93 (48%), Gaps = 1/93 (1%)
Frame = +1
Query: 91 SMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTP-DQLKDIDAKVRKEVDEATK 267
S+ P T R R+ +Q R++ +P++S + NH L +P D++ D+D V +EA
Sbjct: 188 SLESPHTPLRRRN-IQPTRRSMEPVSSPPGEPENHPLSSPEDEIADLDLSVFSGKEEA-- 244
Query: 268 QSKTEPEVGIEELSADIYYKNLEPFVRGIHPAA 366
K + L + + NL +R + AA
Sbjct: 245 PDKKTSRLPFSPLKS-AFKSNLTASLRALRQAA 276
>UniRef50_P45303 Cluster: 2-oxoglutarate dehydrogenase E1 component;
n=70; Proteobacteria|Rep: 2-oxoglutarate dehydrogenase
E1 component - Haemophilus influenzae
Length = 935
Score = 33.9 bits (74), Expect = 3.1
Identities = 18/87 (20%), Positives = 45/87 (51%)
Frame = +1
Query: 7 AARFAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKI 186
AAR A+EY N K + +++ +YR GH+ +D + + +++ P + +++
Sbjct: 436 AARMAVEYRNLFKRDIFIDLISYRRHGHNEADEPLATQPM-MYSIIKKHPTPRKVYADRL 494
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATK 267
++ ++T +Q+ ++ R +D +
Sbjct: 495 VSEGVMTEEQVTEMANDYRDALDNGDR 521
>UniRef50_UPI0000F2B7FC Cluster: PREDICTED: similar to F-box protein
16,; n=1; Monodelphis domestica|Rep: PREDICTED: similar
to F-box protein 16, - Monodelphis domestica
Length = 501
Score = 33.5 bits (73), Expect = 4.1
Identities = 16/43 (37%), Positives = 23/43 (53%)
Frame = -1
Query: 163 WGLWSASPPAPRLSSDTTCRGPTSNDQSNGTSPSPSPKDLSLR 35
+G+W+ SPPA L T S+ N T+P P+P+ S R
Sbjct: 394 FGVWTRSPPASSLIFKTRDSPSPSSRVRNATTPYPTPEPRSFR 436
>UniRef50_A6Q7R1 Cluster: Putative uncharacterized protein; n=1;
Sulfurovum sp. NBC37-1|Rep: Putative uncharacterized
protein - Sulfurovum sp. (strain NBC37-1)
Length = 383
Score = 33.5 bits (73), Expect = 4.1
Identities = 19/70 (27%), Positives = 34/70 (48%), Gaps = 1/70 (1%)
Frame = +1
Query: 109 TSYRTRDEVQEVRQ-TRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEP 285
TS RD EV + T+D IT+ + + + + KD V K++++ATK +
Sbjct: 89 TSKDVRDATVEVAEDTKDSITNTTKDLKDSTTIASKDFKDSAISVSKDINDATKTVSNDS 148
Query: 286 EVGIEELSAD 315
++ +S D
Sbjct: 149 RDSVKTVSND 158
>UniRef50_Q9FNY4 Cluster: DNA polymerase lambda; n=31;
Spermatophyta|Rep: DNA polymerase lambda - Arabidopsis
thaliana (Mouse-ear cress)
Length = 529
Score = 33.5 bits (73), Expect = 4.1
Identities = 19/72 (26%), Positives = 35/72 (48%), Gaps = 1/72 (1%)
Frame = -2
Query: 270 LFSGLVYFFTYLGVDILEL-IWRDELVIQDLLLERSDGVSGLPHLLHLVSRPIRRAGVRH 94
+F+G+V F +GV L IW+ +LV ++E + H+L + + +
Sbjct: 18 MFAGMVVFMVEIGVQRRRLQIWKQKLVQMGAVIEEDRVTKKVTHVLAMNLEALLHKFGKE 77
Query: 93 RMTRVTVRLHLH 58
R++ T RL L+
Sbjct: 78 RLSHFTARLMLY 89
>UniRef50_A5KBH9 Cluster: Putative uncharacterized protein; n=1;
Plasmodium vivax|Rep: Putative uncharacterized protein -
Plasmodium vivax
Length = 1860
Score = 33.5 bits (73), Expect = 4.1
Identities = 17/56 (30%), Positives = 33/56 (58%)
Frame = +1
Query: 136 QEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEE 303
+++++T ITS KI+N+E D K++ + K+VD+A ++ E E I++
Sbjct: 87 EQLKETLRSITSLSTKIVNYETKIEDLEKELKMEKDKQVDKAYEKELKEKENFIKQ 142
>UniRef50_Q1N173 Cluster: Secreted/periplasmic Zn-dependent peptidase,
insulinase-like protein; n=1; Oceanobacter sp. RED65|Rep:
Secreted/periplasmic Zn-dependent peptidase,
insulinase-like protein - Oceanobacter sp. RED65
Length = 920
Score = 33.1 bits (72), Expect = 5.4
Identities = 26/110 (23%), Positives = 51/110 (46%), Gaps = 5/110 (4%)
Frame = +1
Query: 16 FAIEYCNAGKGPLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNH 195
FA Y +G L+ +++ S + + R + + T + S K+ ++N+
Sbjct: 794 FATPYPLLQQGGLLFLVQSPGASSSLLYQETLGFLERQQAEIANMTEEDFESHKQGLINN 853
Query: 196 ELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVG--IEEL-SADI--YYKN 330
L P LKD +++ ++DE + T+ + IE+L +DI YY +
Sbjct: 854 LLKKPTNLKDKASELWSDLDEGNLEFNTKQALADYIEDLDKSDIEEYYNS 903
>UniRef50_Q8MZ38 Cluster: LP06735p; n=3; Drosophila
melanogaster|Rep: LP06735p - Drosophila melanogaster
(Fruit fly)
Length = 393
Score = 33.1 bits (72), Expect = 5.4
Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 4/66 (6%)
Frame = +1
Query: 193 HELVTPD---QLKDIDAKVRKEVDEATKQSKTE-PEVGIEELSADIYYKNLEPFVRGIHP 360
++LV+PD ++K+ + + E+ +Q PEV EL+ + E RG+H
Sbjct: 190 NKLVSPDGKHEIKEFELLAPNMMIESVQQELNYGPEVLPPELAGVLLLNAAENTPRGLHN 249
Query: 361 AAPLKH 378
AAPLKH
Sbjct: 250 AAPLKH 255
>UniRef50_Q7Q6F7 Cluster: ENSANGP00000004512; n=2; Diptera|Rep:
ENSANGP00000004512 - Anopheles gambiae str. PEST
Length = 1179
Score = 33.1 bits (72), Expect = 5.4
Identities = 16/62 (25%), Positives = 35/62 (56%)
Frame = +1
Query: 109 TSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPE 288
T+Y+ + Q +RQTR+ FK++++N + + KD+ KV + + + Q++ + +
Sbjct: 1117 TNYKAKQSKQ-LRQTRERSKKFKKELVNEKFKKLQRQKDLKKKVFRAISKMDTQNEEKMK 1175
Query: 289 VG 294
G
Sbjct: 1176 KG 1177
>UniRef50_A7TKI2 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 531
Score = 33.1 bits (72), Expect = 5.4
Identities = 13/42 (30%), Positives = 23/42 (54%)
Frame = +1
Query: 274 KTEPEVGIEELSADIYYKNLEPFVRGIHPAAPLKHLEVQPRN 399
K EP+VG++ A Y++ L V +H + H +++P N
Sbjct: 106 KIEPDVGVDSEVAQFYFQQLIRAVSYLHDECGIAHRDIKPEN 147
>UniRef50_UPI00015A6B18 Cluster: UPI00015A6B18 related cluster; n=2;
Danio rerio|Rep: UPI00015A6B18 UniRef100 entry - Danio
rerio
Length = 225
Score = 32.7 bits (71), Expect = 7.1
Identities = 15/34 (44%), Positives = 24/34 (70%)
Frame = +1
Query: 187 LNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPE 288
L H+L+TP+QLK+I+A++ +E K+ K E E
Sbjct: 8 LAHDLITPEQLKNIEARL-TATEETLKELKRENE 40
>UniRef50_Q7N5R1 Cluster: Similar to 3-methyl-2-oxobutanoate
dehydrogenase; n=1; Photorhabdus luminescens subsp.
laumondii|Rep: Similar to 3-methyl-2-oxobutanoate
dehydrogenase - Photorhabdus luminescens subsp.
laumondii
Length = 665
Score = 32.7 bits (71), Expect = 7.1
Identities = 23/80 (28%), Positives = 37/80 (46%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P ++ R HS SD YRT DE+ EV Q DPI ++ + +T L +
Sbjct: 240 PCILVCRMDRLDSHSNSDSHKLYRTPDEL-EVLQ--DPIENYVAYLKEKGAITEQALAEQ 296
Query: 229 DAKVRKEVDEATKQSKTEPE 288
+++ +V E ++ E E
Sbjct: 297 KERIKADVAEIFERVYHEEE 316
>UniRef50_Q10WZ2 Cluster: Diguanylate cyclase; n=1; Trichodesmium
erythraeum IMS101|Rep: Diguanylate cyclase -
Trichodesmium erythraeum (strain IMS101)
Length = 357
Score = 32.7 bits (71), Expect = 7.1
Identities = 17/55 (30%), Positives = 30/55 (54%)
Frame = +1
Query: 133 VQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGI 297
VQ+++Q + SF EK+ + + D+LK K ++++ K S T+P GI
Sbjct: 145 VQKLKQREQQLNSFNEKLTHEVRIRTDELK----KQNEQLEHLLKISNTDPLTGI 195
>UniRef50_A5ZLL3 Cluster: Putative uncharacterized protein; n=1;
Bacteroides caccae ATCC 43185|Rep: Putative
uncharacterized protein - Bacteroides caccae ATCC 43185
Length = 220
Score = 32.7 bits (71), Expect = 7.1
Identities = 14/35 (40%), Positives = 23/35 (65%)
Frame = +1
Query: 361 AAPLKHLEVQPRNH*NLNIDYIYIIHSIVTMLKKN 465
+ PL++LE+QPR NL IY++ ++ +KKN
Sbjct: 143 STPLEYLEIQPRILRNLRRYNIYLLEDLLRFIKKN 177
>UniRef50_A5KKL0 Cluster: Putative uncharacterized protein; n=1;
Ruminococcus torques ATCC 27756|Rep: Putative
uncharacterized protein - Ruminococcus torques ATCC
27756
Length = 209
Score = 32.7 bits (71), Expect = 7.1
Identities = 15/38 (39%), Positives = 26/38 (68%), Gaps = 1/38 (2%)
Frame = +1
Query: 193 HELVTP-DQLKDIDAKVRKEVDEATKQSKTEPEVGIEE 303
H L+T ++ +I+A++R+EVD+ ++ EPE GI E
Sbjct: 161 HILITKSEEYMEINAQMRREVDKINQEVSVEPEPGIME 198
>UniRef50_A5G2F5 Cluster: O-antigen polymerase precursor; n=1;
Acidiphilium cryptum JF-5|Rep: O-antigen polymerase
precursor - Acidiphilium cryptum (strain JF-5)
Length = 431
Score = 32.7 bits (71), Expect = 7.1
Identities = 15/43 (34%), Positives = 25/43 (58%)
Frame = -2
Query: 435 YDVNIIYIEVLVVARLDLKVFERGSRVDATDEGFQVLVVYIGG 307
++ I ++V +A + L RGSR D + GF LV+++GG
Sbjct: 68 HETIIALLKVTGLAIIGLAALRRGSRFDRYNPGFAFLVMFVGG 110
>UniRef50_Q177T5 Cluster: Huntingtin interacting protein; n=2;
Culicidae|Rep: Huntingtin interacting protein - Aedes
aegypti (Yellowfever mosquito)
Length = 2367
Score = 32.7 bits (71), Expect = 7.1
Identities = 13/32 (40%), Positives = 22/32 (68%)
Frame = +1
Query: 223 DIDAKVRKEVDEATKQSKTEPEVGIEELSADI 318
++DA V+ V+E+T + EPEV IE+ A++
Sbjct: 520 EVDASVQPVVEESTAPMEVEPEVAIEQTPAEV 551
>UniRef50_A0BF54 Cluster: Chromosome undetermined scaffold_103,
whole genome shotgun sequence; n=1; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_103,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 168
Score = 32.7 bits (71), Expect = 7.1
Identities = 33/136 (24%), Positives = 55/136 (40%), Gaps = 4/136 (2%)
Frame = +1
Query: 88 HSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATK 267
H + D G +E E+ Q + K +LN E+ +K D + +K+ +E +
Sbjct: 9 HKVQDSGFEQNQSNETTEMTQNKGDKNDNKN-LLNSEINEDVSMKKDDVQAKKKDEETQQ 67
Query: 268 QSKTEPEVGIEELSADIYYKNLEPFVRGIHPAAPLKHLEVQPR----NH*NLNIDYIYII 435
QSK + ++ ++ + N ++ A V P N I I
Sbjct: 68 QSKDQNQMYKIKVQTQ-FLNNQSSYINSNSQACIQTQQIVNPSTEKGGEQNNQIHQILNK 126
Query: 436 HSIVTMLKKN*HFCYF 483
+IV +LKKN F YF
Sbjct: 127 ETIVKLLKKN-GFNYF 141
>UniRef50_A3LYH8 Cluster: Checkpoint kinase 1; n=2;
Saccharomycetaceae|Rep: Checkpoint kinase 1 - Pichia
stipitis (Yeast)
Length = 541
Score = 32.7 bits (71), Expect = 7.1
Identities = 17/42 (40%), Positives = 24/42 (57%)
Frame = +1
Query: 274 KTEPEVGIEELSADIYYKNLEPFVRGIHPAAPLKHLEVQPRN 399
K EP VGI+E A Y+K L V IH + + H +++P N
Sbjct: 108 KIEPGVGIDETLAHFYFKQLVNAVDYIH-SKGVAHRDIKPEN 148
>UniRef50_Q3ISB8 Cluster: Transducer protein htr22; n=1;
Natronomonas pharaonis DSM 2160|Rep: Transducer protein
htr22 - Natronomonas pharaonis (strain DSM 2160 / ATCC
35678)
Length = 543
Score = 32.7 bits (71), Expect = 7.1
Identities = 21/69 (30%), Positives = 39/69 (56%), Gaps = 2/69 (2%)
Frame = +1
Query: 118 RTRDEVQEVRQTRDPITSFKEKILNH-ELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVG 294
RT D++ V Q+ + ++ NH E ++ D ++D+DA +++ D A Q++T E+
Sbjct: 410 RTADDIAGVDQSVRTAATDAAEVRNHLETISAD-IEDVDASIQQIADTADTQAQTAQELS 468
Query: 295 -IEELSADI 318
I + ADI
Sbjct: 469 EIVDSVADI 477
>UniRef50_Q09811 Cluster: ATP-dependent DNA helicase hus2/rqh1; n=1;
Schizosaccharomyces pombe|Rep: ATP-dependent DNA
helicase hus2/rqh1 - Schizosaccharomyces pombe (Fission
yeast)
Length = 1328
Score = 32.7 bits (71), Expect = 7.1
Identities = 15/44 (34%), Positives = 23/44 (52%)
Frame = -1
Query: 139 PAPRLSSDTTCRGPTSNDQSNGTSPSPSPKDLSLRCSTRWRTWP 8
P PRL+++ T +N S SP+P +S + S + TWP
Sbjct: 220 PFPRLNNNNTNNNNDNNAIEKRDSASPTPSSVSSQISIDFSTWP 263
>UniRef50_UPI00015B4C52 Cluster: PREDICTED: similar to conserved
hypothetical protein; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to conserved hypothetical protein -
Nasonia vitripennis
Length = 511
Score = 32.3 bits (70), Expect = 9.4
Identities = 17/66 (25%), Positives = 34/66 (51%)
Frame = +1
Query: 127 DEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEEL 306
D+V E Q ++P ++L VT +L+++ R+ ++ Q +PE+ ++ L
Sbjct: 409 DQVLEQAQ-KNPTKVSVAELLQQLTVTQAELENVKVMYRRILESRNSQGALDPEITLQFL 467
Query: 307 SADIYY 324
+ IYY
Sbjct: 468 KSAIYY 473
>UniRef50_Q3USU0 Cluster: Adult male corpora quadrigemina cDNA,
RIKEN full-length enriched library, clone:B230302G16
product:hypothetical Arginine-rich region profile
containing protein, full insert sequence; n=1; Mus
musculus|Rep: Adult male corpora quadrigemina cDNA,
RIKEN full-length enriched library, clone:B230302G16
product:hypothetical Arginine-rich region profile
containing protein, full insert sequence - Mus musculus
(Mouse)
Length = 159
Score = 32.3 bits (70), Expect = 9.4
Identities = 15/42 (35%), Positives = 19/42 (45%)
Frame = -1
Query: 136 APRLSSDTTCRGPTSNDQSNGTSPSPSPKDLSLRCSTRWRTW 11
APR + C P +G P P+P S RCS + R W
Sbjct: 36 APRSGGRSACGCPVGAGDCSGRLPGPAPLAHSRRCSRQPRRW 77
>UniRef50_Q9XX94 Cluster: Putative uncharacterized protein; n=1;
Caenorhabditis elegans|Rep: Putative uncharacterized
protein - Caenorhabditis elegans
Length = 740
Score = 32.3 bits (70), Expect = 9.4
Identities = 18/67 (26%), Positives = 31/67 (46%)
Frame = +1
Query: 142 VRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEELSADIY 321
+RQTR+ + + +L + K A ++KE + TK +K E I EL +
Sbjct: 361 IRQTRETLDIELQIMLKDSINPKSHAKTFAALLKKERETRTKHAKVFMEAKINELDMGNF 420
Query: 322 YKNLEPF 342
Y+ + F
Sbjct: 421 YETYDSF 427
>UniRef50_Q4N857 Cluster: Tash1 protein, putative; n=1; Theileria
parva|Rep: Tash1 protein, putative - Theileria parva
Length = 432
Score = 32.3 bits (70), Expect = 9.4
Identities = 13/51 (25%), Positives = 30/51 (58%)
Frame = +1
Query: 235 KVRKEVDEATKQSKTEPEVGIEELSADIYYKNLEPFVRGIHPAAPLKHLEV 387
K+++ + E +KQS+ +PE I+ L+ ++ +++E + + L H E+
Sbjct: 371 KIQQRIQEKSKQSQVQPEPSIDLLNEPLFDEDVEKLLESELSSTGLSHTEL 421
>UniRef50_Q18288 Cluster: Ubiquitin conjugating enzyme protein 23;
n=1; Caenorhabditis elegans|Rep: Ubiquitin conjugating
enzyme protein 23 - Caenorhabditis elegans
Length = 546
Score = 32.3 bits (70), Expect = 9.4
Identities = 18/58 (31%), Positives = 34/58 (58%), Gaps = 1/58 (1%)
Frame = +1
Query: 166 TSFKEKILNHELVTPDQLKDIDAKV-RKEVDEATKQSKTEPEVGIEELSADIYYKNLE 336
TS +++N ++L++ +V K+V+ TKQ+K E E + + ++YYKNL+
Sbjct: 261 TSDLNEVVNALYEGFEELQEEKLRVLSKQVERKTKQAKVEEERKLIDQQNEVYYKNLK 318
>UniRef50_A2G3C9 Cluster: Putative uncharacterized protein; n=1;
Trichomonas vaginalis G3|Rep: Putative uncharacterized
protein - Trichomonas vaginalis G3
Length = 2287
Score = 32.3 bits (70), Expect = 9.4
Identities = 21/61 (34%), Positives = 26/61 (42%), Gaps = 4/61 (6%)
Frame = -2
Query: 390 LDLKVFERGSRVDATDEGFQVL----VVYIGGQLFNTDFWFRLRLFSGLVYFFTYLGVDI 223
L LK G +D T F L +V N DF L LF+ FFT L +D+
Sbjct: 436 LHLKQINNGISIDITSTAFSALRNGYIVLESQDTDNEDFKIHLELFNENSKFFTRLSIDV 495
Query: 222 L 220
L
Sbjct: 496 L 496
>UniRef50_Q2HHP7 Cluster: Putative uncharacterized protein; n=1;
Chaetomium globosum|Rep: Putative uncharacterized
protein - Chaetomium globosum (Soil fungus)
Length = 277
Score = 32.3 bits (70), Expect = 9.4
Identities = 15/38 (39%), Positives = 22/38 (57%)
Frame = -1
Query: 151 SASPPAPRLSSDTTCRGPTSNDQSNGTSPSPSPKDLSL 38
S +PPA SD T PTS ++ ++PS SP+ +L
Sbjct: 172 STTPPAATTDSDQTQSAPTSPTATDTSTPSESPQSTTL 209
>UniRef50_Q0CEB2 Cluster: Predicted protein; n=2; Trichocomaceae|Rep:
Predicted protein - Aspergillus terreus (strain NIH 2624)
Length = 968
Score = 32.3 bits (70), Expect = 9.4
Identities = 20/52 (38%), Positives = 25/52 (48%)
Frame = +3
Query: 42 ERSFGDGDGDVPLLWSFDVGPRHVVSDERRGAGGEADQRPHHFVQGEDLESR 197
+RS GD + P+ FDVGPR + RG EA R QG E+R
Sbjct: 890 DRSCGDSSDEWPITEEFDVGPRICSTTASRGREVEAQGR--QMDQGRPRETR 939
>UniRef50_A7TLU5 Cluster: Putative uncharacterized protein; n=1;
Vanderwaltozyma polyspora DSM 70294|Rep: Putative
uncharacterized protein - Vanderwaltozyma polyspora DSM
70294
Length = 923
Score = 32.3 bits (70), Expect = 9.4
Identities = 18/62 (29%), Positives = 35/62 (56%)
Frame = +1
Query: 127 DEVQEVRQTRDPITSFKEKILNHELVTPDQLKDIDAKVRKEVDEATKQSKTEPEVGIEEL 306
+EVQ+++Q + E++ E+V KD+ +V+K+ TK+ +P+V +EE
Sbjct: 391 EEVQKLQQKNKQLPELVEEV-KEEVVK----KDVKKEVKKDTKTETKKELVKPDVKVEES 445
Query: 307 SA 312
S+
Sbjct: 446 SS 447
>UniRef50_A6S0G6 Cluster: Predicted protein; n=1; Botryotinia
fuckeliana B05.10|Rep: Predicted protein - Botryotinia
fuckeliana B05.10
Length = 806
Score = 32.3 bits (70), Expect = 9.4
Identities = 24/68 (35%), Positives = 33/68 (48%), Gaps = 5/68 (7%)
Frame = +1
Query: 64 METYRYSGHSMSDPGTSYRTRDEVQEVRQTRD-----PITSFKEKILNHELVTPDQLKDI 228
M R + + GT TRDE + +TRD P T +K K+LN E V D L +I
Sbjct: 726 MPQVRRCSYDLYSDGTRGATRDE--PIFETRDHAEPTPFTQWKIKLLNPEEVNLDGLNEI 783
Query: 229 DAKVRKEV 252
+ + R V
Sbjct: 784 NLRWRGRV 791
>UniRef50_A4QQD9 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 730
Score = 32.3 bits (70), Expect = 9.4
Identities = 22/65 (33%), Positives = 29/65 (44%)
Frame = +3
Query: 9 GQVRHRVLQRRERSFGDGDGDVPLLWSFDVGPRHVVSDERRGAGGEADQRPHHFVQGEDL 188
G +R RV R+ G G G V WS +G R D RRG GG A + + +
Sbjct: 635 GPLRERVRDGLGRA-GGGGGGVRGCWSACLGTRGGEKDRRRGDGGAASGKSRQEMVNDGA 693
Query: 189 ESRAR 203
+R R
Sbjct: 694 LARIR 698
>UniRef50_Q8U3N7 Cluster: Putative uncharacterized protein PF0420;
n=1; Pyrococcus furiosus|Rep: Putative uncharacterized
protein PF0420 - Pyrococcus furiosus
Length = 952
Score = 32.3 bits (70), Expect = 9.4
Identities = 17/42 (40%), Positives = 26/42 (61%)
Frame = -1
Query: 163 WGLWSASPPAPRLSSDTTCRGPTSNDQSNGTSPSPSPKDLSL 38
W ++ A+PP +S + T PT QSN T+P+P+P+ SL
Sbjct: 318 WVIFDATPP---MSLEET---PTQETQSNTTTPTPTPEKCSL 353
>UniRef50_A7D3P2 Cluster: Pyruvate dehydrogenase; n=1; Halorubrum
lacusprofundi ATCC 49239|Rep: Pyruvate dehydrogenase -
Halorubrum lacusprofundi ATCC 49239
Length = 382
Score = 32.3 bits (70), Expect = 9.4
Identities = 27/103 (26%), Positives = 46/103 (44%), Gaps = 3/103 (2%)
Frame = +1
Query: 49 PLVMEMETYRYSGHSMSDPGTSYRTRDEVQEVRQTRDPITSFKEKILNHELVTPDQLKDI 228
P ++E YR+ H+ +D T+YR D V R DP+ + + + D +
Sbjct: 264 PALIEFLEYRFGAHTTADDPTAYRDPDAVDPWR-ALDPLDRMEAFLRETGRIDDDGV--- 319
Query: 229 DAKVRKEVDEATKQSKTEPEVGIEELSADIY---YKNLEPFVR 348
A + +E DE + E +E AD++ Y +L P +R
Sbjct: 320 -AAIHEEADEIVADAIDFAE-SVEPDPADMFDHAYADLPPELR 360
>UniRef50_Q13029 Cluster: PR domain zinc finger protein 2; n=16;
Amniota|Rep: PR domain zinc finger protein 2 - Homo
sapiens (Human)
Length = 1718
Score = 32.3 bits (70), Expect = 9.4
Identities = 16/37 (43%), Positives = 23/37 (62%)
Frame = -1
Query: 151 SASPPAPRLSSDTTCRGPTSNDQSNGTSPSPSPKDLS 41
+ASP P LSS ++ +S+ S+ +S SPSP LS
Sbjct: 1043 AASPGPPTLSSSSSSSSSSSSFSSSSSSSSPSPPPLS 1079
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 636,111,116
Number of Sequences: 1657284
Number of extensions: 13541204
Number of successful extensions: 55304
Number of sequences better than 10.0: 211
Number of HSP's better than 10.0 without gapping: 51265
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 55060
length of database: 575,637,011
effective HSP length: 97
effective length of database: 414,880,463
effective search space used: 44392209541
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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