Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV19p15r
(779 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC139921-1|AAI39922.1| 414|Homo sapiens peptidylprolyl isomeras... 132 1e-30
AY052405-1|AAL11430.1| 414|Homo sapiens 4-1BB-mediated signalin... 132 1e-30
BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat con... 75 2e-13
AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat con... 75 2e-13
AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat con... 75 2e-13
AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens ... 75 2e-13
AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein pr... 75 2e-13
AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats pr... 75 2e-13
D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein. 74 5e-13
AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein. 74 5e-13
AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein. 74 5e-13
AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat con... 72 2e-12
AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat con... 72 2e-12
AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat con... 72 2e-12
AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat con... 72 2e-12
AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat con... 72 2e-12
AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat con... 72 2e-12
AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat con... 72 2e-12
AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat con... 72 2e-12
AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat con... 72 2e-12
AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein. 72 2e-12
BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein. 69 1e-11
AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens ... 69 1e-11
AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein. 69 1e-11
BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting prote... 68 3e-11
BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting prote... 68 3e-11
BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein. 68 3e-11
AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein... 68 3e-11
AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein. 68 3e-11
AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting prote... 68 3e-11
AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein. 68 3e-11
BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat con... 67 8e-11
AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein. 67 8e-11
AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat con... 67 8e-11
AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens ... 67 8e-11
BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein. 65 2e-10
BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats an... 65 2e-10
AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein. 65 2e-10
U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein. 65 3e-10
U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog prot... 65 3e-10
BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog (D... 65 3e-10
BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat con... 65 3e-10
BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein. 65 3e-10
AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats an... 65 3e-10
AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat con... 65 3e-10
AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats an... 65 3e-10
AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat con... 65 3e-10
AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens ... 65 3e-10
AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog va... 65 3e-10
BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein. 64 4e-10
BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein. 64 4e-10
AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isofor... 64 4e-10
AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isofor... 64 4e-10
AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar t... 64 4e-10
AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein. 64 4e-10
AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein. 64 7e-10
L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein. 63 9e-10
CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein. 63 9e-10
CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein. 63 9e-10
BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein. 63 9e-10
BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein. 63 9e-10
BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein. 63 9e-10
BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat con... 63 9e-10
BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of cle... 63 9e-10
BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat con... 63 9e-10
BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein ... 63 9e-10
BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein. 63 9e-10
BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein ... 63 9e-10
AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein. 63 9e-10
AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein ... 63 9e-10
AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of cle... 63 9e-10
AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of cle... 63 9e-10
AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens ... 63 9e-10
AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR... 63 9e-10
AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat pro... 63 9e-10
AL391728-3|CAH73693.1| 217|Homo sapiens leucine rich repeat con... 63 1e-09
AL359894-1|CAH73131.1| 217|Homo sapiens leucine rich repeat con... 63 1e-09
AL359412-3|CAH74020.1| 217|Homo sapiens leucine rich repeat con... 63 1e-09
AL117353-2|CAI23424.1| 217|Homo sapiens leucine rich repeat con... 63 1e-09
AF498274-1|AAP06801.1| 217|Homo sapiens densin-180 like protein... 63 1e-09
BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine r... 62 2e-09
BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine r... 62 2e-09
AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens ... 62 2e-09
AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein. 62 2e-09
BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein. 60 7e-09
AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein ... 60 9e-09
BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat con... 60 1e-08
AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein. 60 1e-08
AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat con... 60 1e-08
AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat con... 60 1e-08
BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats an... 59 2e-08
BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and... 59 2e-08
AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein pr... 59 2e-08
AL445222-17|CAH72931.1| 696|Homo sapiens leucine rich repeat an... 59 2e-08
AL445222-16|CAH72930.1| 723|Homo sapiens leucine rich repeat an... 59 2e-08
AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal p... 59 2e-08
AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein. 59 2e-08
AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens ... 59 2e-08
AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat con... 58 3e-08
J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precur... 58 5e-08
BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N, pol... 58 5e-08
AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and... 57 6e-08
AY358137-1|AAQ88504.1| 255|Homo sapiens VKGE9338 protein. 57 8e-08
AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich repeat-con... 57 8e-08
BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat con... 56 1e-07
AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat con... 56 1e-07
AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens ... 56 1e-07
BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat con... 56 1e-07
BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat con... 56 1e-07
BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat con... 56 1e-07
AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein. 56 1e-07
AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich repeat-con... 56 1e-07
AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat con... 56 1e-07
AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens ... 56 1e-07
AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein. 56 1e-07
BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein. 56 2e-07
AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens ... 56 2e-07
BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte di... 55 3e-07
AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein. 55 3e-07
BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kin... 54 4e-07
BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat con... 54 4e-07
AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kin... 54 4e-07
AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein. 54 4e-07
AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat con... 54 4e-07
D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein. 54 8e-07
BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein. 54 8e-07
BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat con... 54 8e-07
BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein. 54 8e-07
BC036722-1|AAH36722.1| 261|Homo sapiens leucine rich repeat con... 54 8e-07
BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat con... 54 8e-07
BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein. 54 8e-07
AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein pr... 54 8e-07
AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens ... 54 8e-07
AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens ... 54 8e-07
AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leuci... 54 8e-07
AB033020-1|BAA86508.1| 575|Homo sapiens KIAA1194 protein protein. 54 8e-07
BC007504-1|AAH07504.1| 712|Homo sapiens leucine-rich repeats an... 53 1e-06
AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich repeat-con... 53 1e-06
AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein. 53 1e-06
BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein. 52 2e-06
AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats an... 52 2e-06
AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats an... 52 2e-06
AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats an... 52 2e-06
AK058188-1|BAB71707.1| 475|Homo sapiens protein ( Homo sapiens ... 52 3e-06
BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth fac... 51 4e-06
M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth facto... 51 5e-06
AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like ... 51 5e-06
AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit pro... 51 5e-06
BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich repeat-con... 50 7e-06
AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor p... 50 7e-06
AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich repeat-con... 50 7e-06
BC026112-1|AAH26112.1| 116|Homo sapiens hypothetical protein LO... 49 2e-05
BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product p... 48 4e-05
AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein. 48 4e-05
BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein. 48 5e-05
BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein. 48 5e-05
AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein. 48 5e-05
AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein. 48 5e-05
AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich repeat-con... 48 5e-05
DQ013130-1|AAY67799.1| 2014|Homo sapiens leucine-rich repeat kin... 47 7e-05
BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosoph... 47 9e-05
BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein. 47 9e-05
BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein. 47 9e-05
AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein. 47 9e-05
AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein. 47 9e-05
AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein. 47 9e-05
AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein. 47 9e-05
BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine r... 46 1e-04
AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens ... 46 1e-04
AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein. 46 1e-04
BC150568-1|AAI50569.1| 370|Homo sapiens leucine-rich repeats an... 45 3e-04
BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein. 45 3e-04
AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich repeat-con... 45 3e-04
AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens ... 45 3e-04
AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich repeat-con... 45 3e-04
BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein. 44 5e-04
BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein. 44 5e-04
BC030547-1|AAH30547.1| 647|Homo sapiens hypothetical protein DK... 44 5e-04
Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein. 44 6e-04
BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like fami... 44 6e-04
BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like fami... 44 6e-04
BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein. 44 6e-04
AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein. 44 6e-04
AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein. 44 6e-04
AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein. 44 6e-04
AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein. 44 6e-04
AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein. 44 6e-04
AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein. 44 6e-04
AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like fami... 44 6e-04
AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like fami... 44 6e-04
AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens ... 44 6e-04
AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein. 44 6e-04
AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein. 44 6e-04
BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat tra... 44 8e-04
BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat tra... 44 8e-04
BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein. 44 8e-04
BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with ... 44 8e-04
AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor ... 44 8e-04
AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein A... 44 8e-04
AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat tra... 44 8e-04
AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein. 44 8e-04
AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein. 44 8e-04
AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein. 44 8e-04
BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats an... 43 0.001
BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats an... 43 0.001
AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and immuno... 43 0.001
AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein. 43 0.001
AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein. 43 0.001
AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein. 43 0.001
AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat neu... 43 0.001
AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on chr... 43 0.001
BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich alpha-2-gl... 43 0.001
AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich alpha-2-gl... 43 0.001
X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin gl... 42 0.002
X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin gl... 42 0.002
M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin gl... 42 0.002
BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosoph... 42 0.002
BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein. 42 0.002
BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat con... 42 0.002
BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat neu... 42 0.002
BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N, pol... 42 0.002
BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat neu... 42 0.002
BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin ... 42 0.002
AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin ... 42 0.002
AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein. 42 0.002
AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellula... 42 0.002
AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein. 42 0.002
BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like fami... 42 0.002
BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like fami... 42 0.002
BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like fami... 42 0.002
BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like fami... 42 0.002
AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens ... 42 0.002
BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich alpha-2-gl... 42 0.003
AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein. 42 0.003
AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein. 42 0.003
AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens ... 42 0.003
AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich alpha-2-gl... 42 0.003
BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein. 41 0.004
AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich... 41 0.004
AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich... 41 0.004
AK130975-1|BAC85472.1| 209|Homo sapiens protein ( Homo sapiens ... 41 0.004
AB209379-1|BAD92616.1| 245|Homo sapiens hypothetical protein DK... 41 0.004
D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein. 41 0.006
BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein. 41 0.006
BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7 pr... 41 0.006
AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein. 41 0.006
AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7 pr... 41 0.006
AF200348-1|AAF06354.1| 1496|Homo sapiens melanoma-associated ant... 41 0.006
AB051551-1|BAB21855.1| 1029|Homo sapiens KIAA1764 protein protein. 41 0.006
BC051738-1|AAH51738.1| 696|Homo sapiens SLIT and NTRK-like fami... 40 0.008
AY358289-1|AAQ88656.1| 696|Homo sapiens LLWI233 protein. 40 0.008
AL355481-1|CAC37488.1| 696|Homo sapiens SLIT and NTRK-like fami... 40 0.008
AB067497-1|BAB67803.1| 760|Homo sapiens KIAA1910 protein protein. 40 0.008
BC074741-1|AAH74741.1| 345|Homo sapiens leucine-rich repeats an... 40 0.010
AK127729-1|BAC87105.1| 870|Homo sapiens protein ( Homo sapiens ... 40 0.010
AF225421-1|AAG09723.1| 345|Homo sapiens HT017 protein. 40 0.010
U88540-1|AAC34137.1| 786|Homo sapiens Toll-like receptor 1 prot... 40 0.013
D13637-1|BAA02801.2| 789|Homo sapiens KIAA0012 protein. 40 0.013
CR533562-1|CAG38593.1| 786|Homo sapiens TLR1 protein. 40 0.013
BC109094-1|AAI09095.1| 786|Homo sapiens toll-like receptor 1 pr... 40 0.013
BC109093-1|AAI09094.1| 786|Homo sapiens toll-like receptor 1 pr... 40 0.013
BC103509-1|AAI03510.1| 958|Homo sapiens SLIT and NTRK-like fami... 40 0.013
BC099650-1|AAH99650.1| 907|Homo sapiens leucine-rich repeat-con... 40 0.013
BC098287-1|AAH98287.1| 958|Homo sapiens SLIT and NTRK-like fami... 40 0.013
BC098106-1|AAH98106.1| 958|Homo sapiens SLIT and NTRK-like fami... 40 0.013
BC096324-1|AAH96324.1| 907|Homo sapiens leucine-rich repeat-con... 40 0.013
BC089403-1|AAH89403.1| 786|Homo sapiens toll-like receptor 1 pr... 40 0.013
AL603883-1|CAH73026.1| 958|Homo sapiens SLIT and NTRK-like fami... 40 0.013
AF062006-1|AAC28019.1| 907|Homo sapiens orphan G protein-couple... 40 0.013
AB020725-1|BAA74941.1| 966|Homo sapiens KIAA0918 protein protein. 40 0.013
BC040188-1|AAH40188.1| 692|Homo sapiens LOC150356 protein protein. 39 0.018
AF346711-1|AAK31153.1| 951|Homo sapiens G-protein couple recept... 39 0.018
AF257182-1|AAF68989.1| 951|Homo sapiens G-protein-coupled recep... 39 0.018
AB020807-1|BAA78631.1| 796|Homo sapiens TLR6 protein. 39 0.018
BC101077-1|AAI01078.1| 1041|Homo sapiens toll-like receptor 8 pr... 39 0.023
BC101076-1|AAI01077.1| 1041|Homo sapiens toll-like receptor 8 pr... 39 0.023
BC101075-1|AAI01076.1| 1041|Homo sapiens toll-like receptor 8 pr... 39 0.023
BC101074-1|AAI01075.1| 1041|Homo sapiens toll-like receptor 8 pr... 39 0.023
BC040732-1|AAH40732.1| 269|Homo sapiens LRTM1 protein protein. 39 0.023
BC033039-1|AAH33039.1| 927|Homo sapiens LGR4 protein protein. 39 0.023
AY358296-1|AAQ88663.1| 1041|Homo sapiens TLR8 protein. 39 0.023
AF246971-1|AAF64061.1| 1059|Homo sapiens Toll-like receptor 8 pr... 39 0.023
AF245703-1|AAF78036.1| 1041|Homo sapiens toll-like receptor 8 pr... 39 0.023
AB209743-1|BAD92980.1| 1032|Homo sapiens Leucine-rich repeat-con... 39 0.023
AK127177-1|BAC86870.1| 279|Homo sapiens protein ( Homo sapiens ... 38 0.031
BC146761-1|AAI46762.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 38 0.041
BC131897-1|AAI31898.1| 420|Homo sapiens LRRC4B protein protein. 38 0.041
BC114551-1|AAI14552.1| 334|Homo sapiens ISLR2 protein protein. 38 0.041
BC035645-1|AAH35645.1| 1266|Homo sapiens Similar to RIKEN cDNA 3... 38 0.041
BC032460-1|AAH32460.1| 634|Homo sapiens LRRC4B protein protein. 38 0.041
BC009436-1|AAH09436.1| 610|Homo sapiens Unknown (protein for IM... 38 0.041
AY358306-1|AAQ88673.1| 616|Homo sapiens GPR125 protein. 38 0.041
AL512424-5|CAI14258.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 38 0.041
AL512424-4|CAI14259.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 38 0.041
AL442123-4|CAH70918.1| 1534|Homo sapiens slit homolog 1 (Drosoph... 38 0.041
AL442123-3|CAH70917.1| 1461|Homo sapiens slit homolog 1 (Drosoph... 38 0.041
AB017167-1|BAA35184.1| 1534|Homo sapiens Slit-1 protein protein. 38 0.041
AB011537-1|BAA32465.3| 1618|Homo sapiens MEGF4 protein. 38 0.041
Z24680-1|CAA80847.1| 662|Homo sapiens garp protein. 38 0.054
DQ084201-1|AAY86708.1| 640|Homo sapiens netrin-G1 ligand splice... 38 0.054
BC070079-1|AAH70079.1| 662|Homo sapiens LRRC32 protein protein. 38 0.054
BC052210-1|AAH52210.2| 552|Homo sapiens LRRC32 protein protein. 38 0.054
BC030701-1|AAH30701.3| 933|Homo sapiens LRRCC1 protein protein. 38 0.054
AF245702-1|AAF78035.1| 1049|Homo sapiens toll-like receptor 7 pr... 38 0.054
Z23091-1|CAA80637.1| 560|Homo sapiens platelet glycoprotein V p... 37 0.071
L11238-1|AAA03069.1| 560|Homo sapiens platelet membrane glycopr... 37 0.071
BX538330-1|CAD98099.1| 358|Homo sapiens hypothetical protein pr... 37 0.071
BC113717-1|AAI13718.1| 581|Homo sapiens leucine rich repeat tra... 37 0.071
BC113715-1|AAI13716.1| 581|Homo sapiens leucine rich repeat tra... 37 0.071
BC111492-1|AAI11493.1| 581|Homo sapiens leucine rich repeat tra... 37 0.071
BC068590-1|AAH68590.1| 778|Homo sapiens LOC150356 protein protein. 37 0.071
AY358315-1|AAQ88681.1| 513|Homo sapiens GFNV803 protein. 37 0.071
AY182028-1|AAO67549.1| 513|Homo sapiens leucine-rich repeat tra... 37 0.071
AL035681-1|CAI22653.1| 762|Homo sapiens protein ( Human DNA seq... 37 0.071
Z93015-1|CAI42364.1| 481|Homo sapiens nyctalopin protein. 37 0.094
BT007440-1|AAP36108.1| 353|Homo sapiens hypothetical protein, e... 37 0.094
BC112242-1|AAI12243.1| 481|Homo sapiens nyctalopin protein. 37 0.094
BC074943-1|AAH74943.1| 332|Homo sapiens opticin protein. 37 0.094
BC074942-1|AAH74942.1| 332|Homo sapiens opticin protein. 37 0.094
BC041374-1|AAH41374.3| 640|Homo sapiens LRRC4C protein protein. 37 0.094
BC020975-1|AAH20975.1| 353|Homo sapiens tsukushin protein. 37 0.094
AY358317-1|AAQ88683.1| 353|Homo sapiens E2IG4 protein. 37 0.094
AY358293-1|AAQ88660.1| 640|Homo sapiens LNKM292 protein. 37 0.094
AY077681-1|AAL78286.1| 332|Homo sapiens opticin protein. 37 0.094
AL391817-3|CAI17035.1| 332|Homo sapiens opticin protein. 37 0.094
AJ278865-1|CAC19014.1| 481|Homo sapiens leucine-rich repeat pro... 37 0.094
AJ133790-1|CAB53459.1| 332|Homo sapiens opticin protein. 37 0.094
AF254868-1|AAG42685.1| 481|Homo sapiens nyctalopin protein. 37 0.094
AF161702-1|AAD45900.1| 332|Homo sapiens oculoglycan protein. 37 0.094
AB046800-1|BAB13406.1| 640|Homo sapiens KIAA1580 protein protein. 37 0.094
BC119649-1|AAI19650.1| 257|Homo sapiens leucine rich repeat con... 36 0.12
BC119648-1|AAI19649.1| 257|Homo sapiens leucine rich repeat con... 36 0.12
BC028292-1|AAH28292.1| 402|Homo sapiens PODN protein protein. 36 0.12
AY358120-1|AAQ88487.1| 257|Homo sapiens LLR protein protein. 36 0.12
AY061857-1|AAL35741.1| 257|Homo sapiens leucine-rich repeat dom... 36 0.12
AF191019-1|AAF09483.1| 353|Homo sapiens E2IG4 protein. 36 0.12
AB058646-1|BAB40229.1| 257|Homo sapiens LRRC3 protein. 36 0.12
BC080586-1|AAH80586.1| 743|Homo sapiens MXRA5 protein protein. 36 0.16
BC064986-1|AAH64986.1| 743|Homo sapiens MXRA5 protein protein. 36 0.16
BC024001-1|AAH24001.1| 184|Homo sapiens leucine rich repeat con... 36 0.16
BC011846-1|AAH11846.1| 743|Homo sapiens MXRA5 protein protein. 36 0.16
AY358318-1|AAQ88684.1| 184|Homo sapiens LKKM2429 protein. 36 0.16
AL355138-5|CAI12602.1| 175|Homo sapiens leucine rich repeat con... 36 0.16
AL355138-3|CAI12600.1| 184|Homo sapiens leucine rich repeat con... 36 0.16
AK094734-1|BAC04409.1| 184|Homo sapiens protein ( Homo sapiens ... 36 0.16
AK091588-1|BAC03702.1| 213|Homo sapiens protein ( Homo sapiens ... 36 0.16
AF245505-1|AAF86402.1| 2828|Homo sapiens adlican protein. 36 0.16
M65153-1|AAA52287.1| 394|Homo sapiens biglycan protein. 36 0.22
BX537976-1|CAD97940.1| 693|Homo sapiens hypothetical protein pr... 36 0.22
BC107493-1|AAI07494.1| 699|Homo sapiens extracellular matrix pr... 36 0.22
BC105958-1|AAI05959.1| 677|Homo sapiens ECM2 protein protein. 36 0.22
AL157827-4|CAI12589.1| 699|Homo sapiens extracellular matrix pr... 36 0.22
AL137848-1|CAI16693.1| 699|Homo sapiens extracellular matrix pr... 36 0.22
AB011792-1|BAA33958.1| 699|Homo sapiens extracellular matrix pr... 36 0.22
U93091-1|AAC80227.1| 839|Homo sapiens Toll protein homolog prot... 35 0.29
U88880-1|AAC34135.1| 799|Homo sapiens Toll-like receptor 4 prot... 35 0.29
BC117422-1|AAI17423.1| 839|Homo sapiens toll-like receptor 4 pr... 35 0.29
AY029183-1|AAK31796.1| 798|Homo sapiens SLIT1 isoform B protein. 35 0.29
AL512424-1|CAI14255.1| 782|Homo sapiens slit homolog 1 (Drosoph... 35 0.29
AL160272-2|CAH72619.1| 799|Homo sapiens toll-like receptor 4 pr... 35 0.29
AL160272-1|CAH72618.1| 839|Homo sapiens toll-like receptor 4 pr... 35 0.29
AF177765-1|AAF05316.1| 839|Homo sapiens toll-like receptor 4 pr... 35 0.29
AF172171-1|AAF89753.1| 839|Homo sapiens toll-like receptor 4 pr... 35 0.29
AB033011-1|BAA86499.1| 403|Homo sapiens KIAA1185 protein protein. 35 0.29
BC109111-1|AAI09112.1| 811|Homo sapiens TLR10 protein protein. 35 0.38
BC089406-1|AAH89406.1| 811|Homo sapiens TLR10 protein protein. 35 0.38
AY877349-1|AAX70929.1| 1463|Homo sapiens cardiac peroxidase prot... 35 0.38
AY358300-1|AAQ88667.1| 811|Homo sapiens TLR10 protein. 35 0.38
AF296673-1|AAK26744.1| 811|Homo sapiens toll-like receptor 10 p... 35 0.38
AF177766-1|AAF07823.1| 752|Homo sapiens human toll-like recepto... 35 0.38
AB040917-1|BAA96008.1| 700|Homo sapiens KIAA1484 protein protein. 35 0.38
U41344-1|AAC18782.1| 382|Homo sapiens prolargin protein. 34 0.50
U29089-1|AAC50230.1| 382|Homo sapiens proline- arginine-rich en... 34 0.50
J04599-1|AAA36009.1| 368|Homo sapiens protein ( Human hPGI mRNA... 34 0.50
CR542270-1|CAG47066.1| 382|Homo sapiens PRELP protein. 34 0.50
CR541787-1|CAG46586.1| 382|Homo sapiens PRELP protein. 34 0.50
BT007323-1|AAP35987.1| 368|Homo sapiens biglycan protein. 34 0.50
BC109119-1|AAI09120.1| 858|Homo sapiens TLR5 protein protein. 34 0.50
BC109118-1|AAI09119.1| 858|Homo sapiens TLR5 protein protein. 34 0.50
BC047653-1|AAH47653.1| 656|Homo sapiens PHLPP protein protein. 34 0.50
BC040986-1|AAH40986.1| 837|Homo sapiens SLIT and NTRK-like fami... 34 0.50
BC032498-1|AAH32498.1| 382|Homo sapiens proline/arginine-rich e... 34 0.50
BC004244-1|AAH04244.1| 368|Homo sapiens biglycan protein. 34 0.50
BC002416-1|AAH02416.1| 368|Homo sapiens biglycan protein. 34 0.50
AL929091-1|CAM28378.1| 858|Homo sapiens toll-like receptor 5 pr... 34 0.50
AL713693-1|CAD28493.1| 689|Homo sapiens hypothetical protein pr... 34 0.50
AL391817-1|CAI17033.1| 382|Homo sapiens proline/arginine-rich e... 34 0.50
AL080239-3|CAI41650.1| 837|Homo sapiens novel protein protein. 34 0.50
AK223302-1|BAD97022.1| 368|Homo sapiens biglycan preproprotein ... 34 0.50
AK057619-1|BAB71535.1| 469|Homo sapiens protein ( Homo sapiens ... 34 0.50
AF051151-1|AAC34376.1| 858|Homo sapiens Toll/interleukin-1 rece... 34 0.50
AB060695-1|BAB43955.1| 858|Homo sapiens Toll-like receptor 5 pr... 34 0.50
BC040879-1|AAH40879.1| 493|Homo sapiens adhesion molecule with ... 34 0.66
AY237007-1|AAO48948.1| 493|Homo sapiens transmembrane protein A... 34 0.66
AL355145-6|CAI22942.1| 493|Homo sapiens adhesion molecule with ... 34 0.66
AL355138-4|CAI12601.1| 134|Homo sapiens leucine rich repeat con... 34 0.66
AK001706-1|BAA91849.1| 184|Homo sapiens protein ( Homo sapiens ... 34 0.66
AB032989-1|BAA86477.1| 437|Homo sapiens KIAA1163 protein protein. 34 0.66
Y08200-1|CAA69382.1| 567|Homo sapiens rab geranylgeranyl transf... 33 0.87
CR541797-1|CAG46596.1| 567|Homo sapiens RABGGTA protein. 33 0.87
BC109112-1|AAI09113.1| 811|Homo sapiens TLR10 protein protein. 33 0.87
BC018370-1|AAH18370.1| 674|Homo sapiens fibronectin leucine ric... 33 0.87
BC003093-1|AAH03093.1| 567|Homo sapiens Rab geranylgeranyltrans... 33 0.87
AY358308-1|AAQ88675.1| 674|Homo sapiens FLRT1 protein. 33 0.87
AF169675-1|AAF28459.1| 674|Homo sapiens leucine-rich repeat tra... 33 0.87
DQ084202-1|AAY86709.1| 640|Homo sapiens netrin-G1 ligand splice... 33 1.2
BC117370-1|AAI17371.1| 1065|Homo sapiens leucine-rich repeats an... 33 1.2
BC117368-1|AAI17369.1| 1065|Homo sapiens leucine-rich repeats an... 33 1.2
BC104037-1|AAI04038.1| 552|Homo sapiens LRIT3 protein protein. 33 1.2
AL357055-1|CAH73254.1| 1065|Homo sapiens leucine-rich repeats an... 33 1.2
AB018349-1|BAA34526.2| 1073|Homo sapiens KIAA0806 protein protein. 33 1.2
U21128-1|AAA91639.1| 338|Homo sapiens lumican protein. 33 1.5
U18728-1|AAA85268.1| 338|Homo sapiens lumican protein. 33 1.5
BT006707-1|AAP35353.1| 338|Homo sapiens lumican protein. 33 1.5
BC035997-1|AAH35997.1| 338|Homo sapiens lumican protein. 33 1.5
BC007038-1|AAH07038.1| 338|Homo sapiens lumican protein. 33 1.5
AY358127-1|AAQ88494.1| 627|Homo sapiens AILP5865 protein. 33 1.5
AK223177-1|BAD96897.1| 338|Homo sapiens lumican variant protein. 33 1.5
AK222484-1|BAD96204.1| 368|Homo sapiens biglycan preproprotein ... 33 1.5
L43619-1|AAC41765.1| 4292|Homo sapiens polycystic kidney disease... 32 2.0
L39891-1|AAB59488.1| 3638|Homo sapiens polycystic kidney disease... 32 2.0
L33243-1|AAC37576.1| 4302|Homo sapiens polycystic kidney disease... 32 2.0
BC110058-1|AAI10059.1| 518|Homo sapiens leucine rich repeat tra... 32 2.0
BC099738-1|AAH99738.1| 518|Homo sapiens leucine rich repeat tra... 32 2.0
BC098301-1|AAH98301.1| 519|Homo sapiens LRRTM4 protein protein. 32 2.0
BC098267-1|AAH98267.1| 519|Homo sapiens LRRTM4 protein protein. 32 2.0
AY358324-1|AAQ88690.1| 590|Homo sapiens GFHL3075 protein. 32 2.0
AY182030-1|AAO67551.1| 518|Homo sapiens leucine-rich repeat tra... 32 2.0
AK126961-1|BAC86764.1| 518|Homo sapiens protein ( Homo sapiens ... 32 2.0
BC142997-1|AAI42998.1| 524|Homo sapiens LGI3 protein protein. 32 2.7
BC114621-1|AAI14622.1| 977|Homo sapiens SLIT and NTRK-like fami... 32 2.7
BC003578-1|AAH03578.1| 628|Homo sapiens leucine rich repeat and... 32 2.7
BC001354-1|AAH01354.1| 259|Homo sapiens leucine rich repeat con... 32 2.7
AL833849-1|CAD38708.1| 633|Homo sapiens hypothetical protein pr... 32 2.7
AK172754-1|BAD18740.1| 628|Homo sapiens protein ( Homo sapiens ... 32 2.7
AC005586-4|AAS00383.1| 259|Homo sapiens unknown protein. 32 2.7
AB208832-1|BAD92069.1| 680|Homo sapiens Hypothetical protein DK... 32 2.7
AB020655-1|BAA74871.2| 988|Homo sapiens KIAA0848 protein protein. 32 2.7
U24497-1|AAC50128.1| 4303|Homo sapiens autosomal dominant polycy... 31 3.5
BC113617-1|AAI13618.1| 757|Homo sapiens relaxin/insulin-like fa... 31 4.7
BC112142-1|AAI12143.1| 757|Homo sapiens leucine-rich repeat-con... 31 4.7
BC050665-1|AAH50665.1| 523|Homo sapiens LRRC48 protein protein. 31 4.7
BC050419-1|AAH50419.1| 523|Homo sapiens LRRC48 protein protein. 31 4.7
BC047873-1|AAH47873.1| 523|Homo sapiens leucine rich repeat con... 31 4.7
BC040276-1|AAH40276.1| 457|Homo sapiens LRRC48 protein protein. 31 4.7
AY899850-1|AAX85198.1| 724|Homo sapiens LGR7.10 protein. 31 4.7
AF190500-1|AAG17167.1| 757|Homo sapiens leucine-rich repeat-con... 31 4.7
AB208943-1|BAD92180.1| 627|Homo sapiens leucine-rich repeat-con... 31 4.7
U88881-1|AAC34136.1| 365|Homo sapiens Toll-like receptor 5 prot... 31 6.1
BC056900-1|AAH56900.1| 1504|Homo sapiens nischarin protein. 30 8.1
BC054494-1|AAH54494.1| 1504|Homo sapiens nischarin protein. 30 8.1
BC038102-1|AAH38102.1| 1504|Homo sapiens nischarin protein. 30 8.1
AF082516-1|AAC33104.1| 1504|Homo sapiens I-1 receptor candidate ... 30 8.1
AB023192-1|BAA76819.1| 1528|Homo sapiens KIAA0975 protein protein. 30 8.1
>BC139921-1|AAI39922.1| 414|Homo sapiens peptidylprolyl isomerase
(cyclophilin)-like 5 protein.
Length = 414
Score = 132 bits (319), Expect = 1e-30
Identities = 89/259 (34%), Positives = 132/259 (50%), Gaps = 2/259 (0%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
P +L+ L S L +L LK L LDLS+N I+KLP G + +L EL+L +N L
Sbjct: 153 PYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHL 212
Query: 598 GVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 419
V L + K+L+ LDL+ NK+ LP +L++L LK +DN + + P I
Sbjct: 213 ESFSVA----LCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKI 268
Query: 418 GRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTSDQYSPWQFYVGSL 239
G++ LR+ + + N+L LP LEY+D+ N F+ + +P +L
Sbjct: 269 GQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGNTFEQPKVLPVIKLQAPL-----TL 323
Query: 238 VHLSAKIILKHKIHYASNIIPWTLVEFLDNANMCVCGAPVVNYTHSINKEYDLKDYFRTV 59
+ SA+ IL ++I Y S+IIP+ L + LD A +CVCG +N +L TV
Sbjct: 324 LESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTMNLHSVAHTV 383
Query: 58 VFNNNLSVVE--FECYFCS 8
V +NL E YFCS
Sbjct: 384 VLVDNLGGTEAPIISYFCS 402
>AY052405-1|AAL11430.1| 414|Homo sapiens 4-1BB-mediated signaling
molecule protein.
Length = 414
Score = 132 bits (319), Expect = 1e-30
Identities = 89/259 (34%), Positives = 132/259 (50%), Gaps = 2/259 (0%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
P +L+ L S L +L LK L LDLS+N I+KLP G + +L EL+L +N L
Sbjct: 153 PYSLEHLQTSYCGLVRVDMRMLCLKSLRKLDLSHNHIKKLPATIGDLIHLQELNLNDNHL 212
Query: 598 GVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 419
V L + K+L+ LDL+ NK+ LP +L++L LK +DN + + P I
Sbjct: 213 ESFSVA----LCHSTLQKSLRSLDLSKNKIKALPVQFCQLQELKNLKLDDNELIQFPCKI 268
Query: 418 GRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTSDQYSPWQFYVGSL 239
G++ LR+ + + N+L LP LEY+D+ N F+ + +P +L
Sbjct: 269 GQLINLRFLSAARNKLPFLPSEFRNLSLEYLDLFGNTFEQPKVLPVIKLQAPL-----TL 323
Query: 238 VHLSAKIILKHKIHYASNIIPWTLVEFLDNANMCVCGAPVVNYTHSINKEYDLKDYFRTV 59
+ SA+ IL ++I Y S+IIP+ L + LD A +CVCG +N +L TV
Sbjct: 324 LESSARTILHNRIPYGSHIIPFHLCQDLDTAKICVCGRFCLNSFIQGTTTMNLHSVAHTV 383
Query: 58 VFNNNLSVVE--FECYFCS 8
V +NL E YFCS
Sbjct: 384 VLVDNLGGTEAPIISYFCS 402
>BC003193-1|AAH03193.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 75.4 bits (177), Expect = 2e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 1/160 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 415 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
Score = 66.9 bits (156), Expect = 8e-11
Identities = 49/159 (30%), Positives = 79/159 (49%), Gaps = 3/159 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L+ L L ++ N I L HL L L N++ +LP E G + NL L ++ N+L
Sbjct: 174 RRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLE 233
Query: 595 VRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
L +I+ L DL + N L +P I KL+KL LK + N +++LP
Sbjct: 234 ---------RLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEA 284
Query: 421 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 308
+G +L ++ N+L +LP S+ + +L ++ NK
Sbjct: 285 VGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNK 323
Score = 65.3 bits (152), Expect = 2e-10
Identities = 46/143 (32%), Positives = 67/143 (46%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L SL L L + L+ L LDL NNEI LP G + +L +L L NQL
Sbjct: 153 LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLS-- 210
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ +G K L LD++ N+L LP+ I L L L + N++ +P IG++
Sbjct: 211 ---ELPQEIGN--LKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKL 265
Query: 409 STLRYFTISSNELQSLPCSLMQC 341
L + N L LP ++ +C
Sbjct: 266 KKLSILKVDQNRLTQLPEAVGEC 288
Score = 63.3 bits (147), Expect = 9e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 2/150 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L++L + N + +LP G +L+EL L NQL L I K KL
Sbjct: 265 LKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQL---------LTLPKSIGKLKKLS 315
Query: 529 DLTS--NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
+L + NKL LPK I L DN ++R+PA + + + L ++ N L LP
Sbjct: 316 NLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL 375
Query: 355 SLMQCRLEYIDISSNKFDNKQNNSTSDQYS 266
SL +L+ + +S N+ T Y+
Sbjct: 376 SLTALKLKALWLSDNQSQPLLTFQTDTDYT 405
>AL513211-1|CAI17358.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 75.4 bits (177), Expect = 2e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 1/160 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 415 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
Score = 66.9 bits (156), Expect = 8e-11
Identities = 49/159 (30%), Positives = 79/159 (49%), Gaps = 3/159 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L+ L L ++ N I L HL L L N++ +LP E G + NL L ++ N+L
Sbjct: 174 RRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLE 233
Query: 595 VRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
L +I+ L DL + N L +P I KL+KL LK + N +++LP
Sbjct: 234 ---------RLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEA 284
Query: 421 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 308
+G +L ++ N+L +LP S+ + +L ++ NK
Sbjct: 285 VGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNK 323
Score = 65.3 bits (152), Expect = 2e-10
Identities = 46/143 (32%), Positives = 67/143 (46%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L SL L L + L+ L LDL NNEI LP G + +L +L L NQL
Sbjct: 153 LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLS-- 210
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ +G K L LD++ N+L LP+ I L L L + N++ +P IG++
Sbjct: 211 ---ELPQEIGN--LKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKL 265
Query: 409 STLRYFTISSNELQSLPCSLMQC 341
L + N L LP ++ +C
Sbjct: 266 KKLSILKVDQNRLTQLPEAVGEC 288
Score = 63.3 bits (147), Expect = 9e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 2/150 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L++L + N + +LP G +L+EL L NQL L I K KL
Sbjct: 265 LKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQL---------LTLPKSIGKLKKLS 315
Query: 529 DLTS--NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
+L + NKL LPK I L DN ++R+PA + + + L ++ N L LP
Sbjct: 316 NLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL 375
Query: 355 SLMQCRLEYIDISSNKFDNKQNNSTSDQYS 266
SL +L+ + +S N+ T Y+
Sbjct: 376 SLTALKLKALWLSDNQSQPLLTFQTDTDYT 405
>AL033384-1|CAI21666.1| 524|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 524
Score = 75.4 bits (177), Expect = 2e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 1/160 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 415 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
Score = 66.9 bits (156), Expect = 8e-11
Identities = 49/159 (30%), Positives = 79/159 (49%), Gaps = 3/159 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L+ L L ++ N I L HL L L N++ +LP E G + NL L ++ N+L
Sbjct: 174 RRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLE 233
Query: 595 VRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
L +I+ L DL + N L +P I KL+KL LK + N +++LP
Sbjct: 234 ---------RLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEA 284
Query: 421 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 308
+G +L ++ N+L +LP S+ + +L ++ NK
Sbjct: 285 VGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNK 323
Score = 65.3 bits (152), Expect = 2e-10
Identities = 46/143 (32%), Positives = 67/143 (46%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L SL L L + L+ L LDL NNEI LP G + +L +L L NQL
Sbjct: 153 LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLS-- 210
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ +G K L LD++ N+L LP+ I L L L + N++ +P IG++
Sbjct: 211 ---ELPQEIGN--LKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKL 265
Query: 409 STLRYFTISSNELQSLPCSLMQC 341
L + N L LP ++ +C
Sbjct: 266 KKLSILKVDQNRLTQLPEAVGEC 288
Score = 63.3 bits (147), Expect = 9e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 2/150 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L++L + N + +LP G +L+EL L NQL L I K KL
Sbjct: 265 LKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQL---------LTLPKSIGKLKKLS 315
Query: 529 DLTS--NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
+L + NKL LPK I L DN ++R+PA + + + L ++ N L LP
Sbjct: 316 NLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL 375
Query: 355 SLMQCRLEYIDISSNKFDNKQNNSTSDQYS 266
SL +L+ + +S N+ T Y+
Sbjct: 376 SLTALKLKALWLSDNQSQPLLTFQTDTDYT 405
>AK021896-1|BAB13929.1| 197|Homo sapiens protein ( Homo sapiens
cDNA FLJ11834 fis, clone HEMBA1006583, weakly similar to
Drosophila melanogaster Scribble (scrib) mRNA. ).
Length = 197
Score = 75.4 bits (177), Expect = 2e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 1/160 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 415 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
>AF359380-1|AAK72246.1| 524|Homo sapiens LANO adaptor protein
protein.
Length = 524
Score = 75.4 bits (177), Expect = 2e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 1/160 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 415 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
Score = 66.9 bits (156), Expect = 8e-11
Identities = 49/159 (30%), Positives = 79/159 (49%), Gaps = 3/159 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L+ L L ++ N I L HL L L N++ +LP E G + NL L ++ N+L
Sbjct: 174 RRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLE 233
Query: 595 VRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
L +I+ L DL + N L +P I KL+KL LK + N +++LP
Sbjct: 234 ---------RLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEA 284
Query: 421 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 308
+G +L ++ N+L +LP S+ + +L ++ NK
Sbjct: 285 VGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNK 323
Score = 65.3 bits (152), Expect = 2e-10
Identities = 46/143 (32%), Positives = 67/143 (46%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L SL L L + L+ L LDL NNEI LP G + +L +L L NQL
Sbjct: 153 LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLS-- 210
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ +G K L LD++ N+L LP+ I L L L + N++ +P IG++
Sbjct: 211 ---ELPQEIGN--LKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKL 265
Query: 409 STLRYFTISSNELQSLPCSLMQC 341
L + N L LP ++ +C
Sbjct: 266 KKLSILKVDQNRLTQLPEAVGEC 288
Score = 63.3 bits (147), Expect = 9e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 2/150 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L++L + N + +LP G +L+EL L NQL L I K KL
Sbjct: 265 LKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQL---------LTLPKSIGKLKKLS 315
Query: 529 DLTS--NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
+L + NKL LPK I L DN ++R+PA + + + L ++ N L LP
Sbjct: 316 NLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL 375
Query: 355 SLMQCRLEYIDISSNKFDNKQNNSTSDQYS 266
SL +L+ + +S N+ T Y+
Sbjct: 376 SLTALKLKALWLSDNQSQPLLTFQTDTDYT 405
>AF332199-1|AAK69623.1| 524|Homo sapiens leucine-rich repeats
protein protein.
Length = 524
Score = 75.4 bits (177), Expect = 2e-13
Identities = 51/160 (31%), Positives = 77/160 (48%), Gaps = 1/160 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 415 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+ L + N L LP SL Q RLE +D+ +N+ N
Sbjct: 149 NLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYN 188
Score = 66.9 bits (156), Expect = 8e-11
Identities = 49/159 (30%), Positives = 79/159 (49%), Gaps = 3/159 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L+ L L ++ N I L HL L L N++ +LP E G + NL L ++ N+L
Sbjct: 174 RRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLE 233
Query: 595 VRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
L +I+ L DL + N L +P I KL+KL LK + N +++LP
Sbjct: 234 ---------RLPEEISGLTSLTDLVISQNLLETIPDGIGKLKKLSILKVDQNRLTQLPEA 284
Query: 421 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 308
+G +L ++ N+L +LP S+ + +L ++ NK
Sbjct: 285 VGECESLTELVLTENQLLTLPKSIGKLKKLSNLNADRNK 323
Score = 65.3 bits (152), Expect = 2e-10
Identities = 46/143 (32%), Positives = 67/143 (46%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L SL L L + L+ L LDL NNEI LP G + +L +L L NQL
Sbjct: 153 LASLELRENLLTYLPDSLTQLRRLEELDLGNNEIYNLPESIGALLHLKDLWLDGNQLS-- 210
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ +G K L LD++ N+L LP+ I L L L + N++ +P IG++
Sbjct: 211 ---ELPQEIGN--LKNLLCLDVSENRLERLPEEISGLTSLTDLVISQNLLETIPDGIGKL 265
Query: 409 STLRYFTISSNELQSLPCSLMQC 341
L + N L LP ++ +C
Sbjct: 266 KKLSILKVDQNRLTQLPEAVGEC 288
Score = 63.3 bits (147), Expect = 9e-10
Identities = 46/150 (30%), Positives = 69/150 (46%), Gaps = 2/150 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L++L + N + +LP G +L+EL L NQL L I K KL
Sbjct: 265 LKKLSILKVDQNRLTQLPEAVGECESLTELVLTENQL---------LTLPKSIGKLKKLS 315
Query: 529 DLTS--NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
+L + NKL LPK I L DN ++R+PA + + + L ++ N L LP
Sbjct: 316 NLNADRNKLVSLPKEIGGCCSLTVFCVRDNRLTRIPAEVSQATELHVLDVAGNRLLHLPL 375
Query: 355 SLMQCRLEYIDISSNKFDNKQNNSTSDQYS 266
SL +L+ + +S N+ T Y+
Sbjct: 376 SLTALKLKALWLSDNQSQPLLTFQTDTDYT 405
>D63481-1|BAA09768.3| 1630|Homo sapiens KIAA0147 protein protein.
Length = 1630
Score = 74.1 bits (174), Expect = 5e-13
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ L L +L + L +L L LS+NEI++LPPE L EL ++ N
Sbjct: 36 RSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRND-- 93
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + + K L++ D + N L LP +L L L ND + LP +G
Sbjct: 94 IPEIPE-----SIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVG 148
Query: 415 RISTLRYFTISSNELQSLPCSL-MQCRLEYIDISSNKFD 302
++ L + N L+SLP SL +LE +D+ N +
Sbjct: 149 NLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLE 187
Score = 58.0 bits (134), Expect = 4e-08
Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL- 533
L L LDL N++E LP G + NL EL L NQL L P++ +L
Sbjct: 173 LVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSA---------LPPELGNLRRLV 223
Query: 532 -LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
LD++ N+L LP + L L L + N++ RLP IG++ L + N L +
Sbjct: 224 CLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTE 283
Query: 355 SLMQC 341
++ C
Sbjct: 284 AIGDC 288
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/140 (30%), Positives = 68/140 (48%), Gaps = 1/140 (0%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
I K L + D S N + +LP F ++ +L+ HLA N + ++ + L +T
Sbjct: 101 IKFCKALEIADFSGNPLSRLPDGFTQLRSLA--HLALNDVSLQALPGDVGNLANLVT--- 155
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
L+L N L LP ++ L KL L N + LP T+G + LR + N+L +LP
Sbjct: 156 --LELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALP 213
Query: 358 CSLMQC-RLEYIDISSNKFD 302
L RL +D+S N+ +
Sbjct: 214 PELGNLRRLVCLDVSENRLE 233
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/165 (29%), Positives = 72/165 (43%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L L LS L I LK L++L + N + ++ G NLSEL L N L
Sbjct: 245 LTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLL--- 301
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ LG ++TK L L++ N L LP I L L DN ++ LP +
Sbjct: 302 --MALPRSLG-KLTK-LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 357
Query: 409 STLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTSD 275
+ L ++ N LQSLP +L L+ + ++ N+ T D
Sbjct: 358 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPMLRFQTED 402
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = -2
Query: 550 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
+++L+ L L +N+L LPK ++L L L +DN I RLP + L +S N++
Sbjct: 35 SRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDI 94
Query: 370 QSLPCSLMQCR-LEYIDISSN 311
+P S+ C+ LE D S N
Sbjct: 95 PEIPESIKFCKALEIADFSGN 115
>AY062238-1|AAL38976.1| 1630|Homo sapiens scribble protein.
Length = 1630
Score = 74.1 bits (174), Expect = 5e-13
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ L L +L + L +L L LS+NEI++LPPE L EL ++ N
Sbjct: 36 RSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRND-- 93
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + + K L++ D + N L LP +L L L ND + LP +G
Sbjct: 94 IPEIPE-----SIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVG 148
Query: 415 RISTLRYFTISSNELQSLPCSL-MQCRLEYIDISSNKFD 302
++ L + N L+SLP SL +LE +D+ N +
Sbjct: 149 NLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLE 187
Score = 58.0 bits (134), Expect = 4e-08
Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL- 533
L L LDL N++E LP G + NL EL L NQL L P++ +L
Sbjct: 173 LVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSA---------LPPELGNLRRLV 223
Query: 532 -LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
LD++ N+L LP + L L L + N++ RLP IG++ L + N L +
Sbjct: 224 CLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTE 283
Query: 355 SLMQC 341
++ C
Sbjct: 284 AIGDC 288
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/140 (30%), Positives = 68/140 (48%), Gaps = 1/140 (0%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
I K L + D S N + +LP F ++ +L+ HLA N + ++ + L +T
Sbjct: 101 IKFCKALEIADFSGNPLSRLPDGFTQLRSLA--HLALNDVSLQALPGDVGNLANLVT--- 155
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
L+L N L LP ++ L KL L N + LP T+G + LR + N+L +LP
Sbjct: 156 --LELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALP 213
Query: 358 CSLMQC-RLEYIDISSNKFD 302
L RL +D+S N+ +
Sbjct: 214 PELGNLRRLVCLDVSENRLE 233
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/165 (29%), Positives = 72/165 (43%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L L LS L I LK L++L + N + ++ G NLSEL L N L
Sbjct: 245 LTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLL--- 301
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ LG ++TK L L++ N L LP I L L DN ++ LP +
Sbjct: 302 --MALPRSLG-KLTK-LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 357
Query: 409 STLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTSD 275
+ L ++ N LQSLP +L L+ + ++ N+ T D
Sbjct: 358 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPMLRFQTED 402
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = -2
Query: 550 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
+++L+ L L +N+L LPK ++L L L +DN I RLP + L +S N++
Sbjct: 35 SRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDI 94
Query: 370 QSLPCSLMQCR-LEYIDISSN 311
+P S+ C+ LE D S N
Sbjct: 95 PEIPESIKFCKALEIADFSGN 115
>AF240677-1|AAP88017.1| 1630|Homo sapiens CRIB1 protein.
Length = 1630
Score = 74.1 bits (174), Expect = 5e-13
Identities = 48/159 (30%), Positives = 76/159 (47%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ L L +L + L +L L LS+NEI++LPPE L EL ++ N
Sbjct: 36 RSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRND-- 93
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + + K L++ D + N L LP +L L L ND + LP +G
Sbjct: 94 IPEIPE-----SIKFCKALEIADFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVG 148
Query: 415 RISTLRYFTISSNELQSLPCSL-MQCRLEYIDISSNKFD 302
++ L + N L+SLP SL +LE +D+ N +
Sbjct: 149 NLANLVTLELRENLLKSLPASLSFLVKLEQLDLGGNDLE 187
Score = 58.0 bits (134), Expect = 4e-08
Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL- 533
L L LDL N++E LP G + NL EL L NQL L P++ +L
Sbjct: 173 LVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSA---------LPPELGNLRRLV 223
Query: 532 -LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
LD++ N+L LP + L L L + N++ RLP IG++ L + N L +
Sbjct: 224 CLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTE 283
Query: 355 SLMQC 341
++ C
Sbjct: 284 AIGDC 288
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/140 (30%), Positives = 68/140 (48%), Gaps = 1/140 (0%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
I K L + D S N + +LP F ++ +L+ HLA N + ++ + L +T
Sbjct: 101 IKFCKALEIADFSGNPLSRLPDGFTQLRSLA--HLALNDVSLQALPGDVGNLANLVT--- 155
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
L+L N L LP ++ L KL L N + LP T+G + LR + N+L +LP
Sbjct: 156 --LELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALP 213
Query: 358 CSLMQC-RLEYIDISSNKFD 302
L RL +D+S N+ +
Sbjct: 214 PELGNLRRLVCLDVSENRLE 233
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/165 (29%), Positives = 72/165 (43%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L L LS L I LK L++L + N + ++ G NLSEL L N L
Sbjct: 245 LTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLL--- 301
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ LG ++TK L L++ N L LP I L L DN ++ LP +
Sbjct: 302 --MALPRSLG-KLTK-LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 357
Query: 409 STLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTSD 275
+ L ++ N LQSLP +L L+ + ++ N+ T D
Sbjct: 358 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPMLRFQTED 402
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/81 (34%), Positives = 44/81 (54%), Gaps = 1/81 (1%)
Frame = -2
Query: 550 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
+++L+ L L +N+L LPK ++L L L +DN I RLP + L +S N++
Sbjct: 35 SRSLEELLLDANQLRELPKPFFRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDI 94
Query: 370 QSLPCSLMQCR-LEYIDISSN 311
+P S+ C+ LE D S N
Sbjct: 95 PEIPESIKFCKALEIADFSGN 115
>AL391728-2|CAH73692.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 51 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 107
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 108 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 163
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 164 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 542
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 188 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 247
Query: 541 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 248 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 307
Query: 397 YFTISSNELQSLPCSL 350
F S NEL+SLP ++
Sbjct: 308 EFDCSCNELESLPSTI 323
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 99 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 158
Query: 598 --GVRGVVDWRWL-LGPQITKTL-----KL-----LDLTSNKLGHLPKAIWKLEKLVTLK 458
+V R L L KTL KL LDL +N+ G LP+ + +++ L L
Sbjct: 159 PANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELW 218
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++N + LP +IG++ L Y +S N ++++ + C LE + +SSN
Sbjct: 219 MDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSN 268
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 270
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 271 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 324
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 302
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 325 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L
Sbjct: 260 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 319
Query: 598 --------GVRGV-VDWRWL--LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R + VD +L L +I K + ++ L SNKL LP+ I +++KL L
Sbjct: 320 PSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLN 379
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ ++L
Sbjct: 380 LSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL391728-1|CAH73691.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 46 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 159 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 542
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 183 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 242
Query: 541 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 243 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 302
Query: 397 YFTISSNELQSLPCSL 350
F S NEL+SLP ++
Sbjct: 303 EFDCSCNELESLPSTI 318
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 94 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 153
Query: 598 --GVRGVVDWRWL-LGPQITKTL-----KL-----LDLTSNKLGHLPKAIWKLEKLVTLK 458
+V R L L KTL KL LDL +N+ G LP+ + +++ L L
Sbjct: 154 PANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELW 213
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++N + LP +IG++ L Y +S N ++++ + C LE + +SSN
Sbjct: 214 MDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSN 263
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 265
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 266 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 319
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 302
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 320 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L
Sbjct: 255 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 314
Query: 598 --------GVRGV-VDWRWL--LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R + VD +L L +I K + ++ L SNKL LP+ I +++KL L
Sbjct: 315 PSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLN 374
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ ++L
Sbjct: 375 LSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL359412-2|CAH74019.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 51 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 107
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 108 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 163
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 164 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 542
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 188 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 247
Query: 541 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 248 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 307
Query: 397 YFTISSNELQSLPCSL 350
F S NEL+SLP ++
Sbjct: 308 EFDCSCNELESLPSTI 323
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 99 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 158
Query: 598 --GVRGVVDWRWL-LGPQITKTL-----KL-----LDLTSNKLGHLPKAIWKLEKLVTLK 458
+V R L L KTL KL LDL +N+ G LP+ + +++ L L
Sbjct: 159 PANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELW 218
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++N + LP +IG++ L Y +S N ++++ + C LE + +SSN
Sbjct: 219 MDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSN 268
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 270
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 271 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 324
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 302
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 325 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L
Sbjct: 260 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 319
Query: 598 --------GVRGV-VDWRWL--LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R + VD +L L +I K + ++ L SNKL LP+ I +++KL L
Sbjct: 320 PSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLN 379
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ ++L
Sbjct: 380 LSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL359412-1|CAH74018.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 46 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 159 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 542
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 183 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 242
Query: 541 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 243 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 302
Query: 397 YFTISSNELQSLPCSL 350
F S NEL+SLP ++
Sbjct: 303 EFDCSCNELESLPSTI 318
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 94 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 153
Query: 598 --GVRGVVDWRWL-LGPQITKTL-----KL-----LDLTSNKLGHLPKAIWKLEKLVTLK 458
+V R L L KTL KL LDL +N+ G LP+ + +++ L L
Sbjct: 154 PANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELW 213
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++N + LP +IG++ L Y +S N ++++ + C LE + +SSN
Sbjct: 214 MDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSN 263
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 265
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 266 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 319
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 302
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 320 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L
Sbjct: 255 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 314
Query: 598 --------GVRGV-VDWRWL--LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R + VD +L L +I K + ++ L SNKL LP+ I +++KL L
Sbjct: 315 PSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLN 374
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ ++L
Sbjct: 375 LSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL158840-2|CAH70975.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 51 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 107
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 108 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 163
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 164 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 542
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 188 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 247
Query: 541 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 248 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 307
Query: 397 YFTISSNELQSLPCSL 350
F S NEL+SLP ++
Sbjct: 308 EFDCSCNELESLPSTI 323
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 99 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 158
Query: 598 --GVRGVVDWRWL-LGPQITKTL-----KL-----LDLTSNKLGHLPKAIWKLEKLVTLK 458
+V R L L KTL KL LDL +N+ G LP+ + +++ L L
Sbjct: 159 PANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELW 218
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++N + LP +IG++ L Y +S N ++++ + C LE + +SSN
Sbjct: 219 MDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSN 268
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 270
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 271 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 324
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 302
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 325 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L
Sbjct: 260 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 319
Query: 598 --------GVRGV-VDWRWL--LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R + VD +L L +I K + ++ L SNKL LP+ I +++KL L
Sbjct: 320 PSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLN 379
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ ++L
Sbjct: 380 LSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL158840-1|CAH70974.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 46 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 159 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 542
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 183 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 242
Query: 541 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 243 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 302
Query: 397 YFTISSNELQSLPCSL 350
F S NEL+SLP ++
Sbjct: 303 EFDCSCNELESLPSTI 318
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 94 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 153
Query: 598 --GVRGVVDWRWL-LGPQITKTL-----KL-----LDLTSNKLGHLPKAIWKLEKLVTLK 458
+V R L L KTL KL LDL +N+ G LP+ + +++ L L
Sbjct: 154 PANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELW 213
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++N + LP +IG++ L Y +S N ++++ + C LE + +SSN
Sbjct: 214 MDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSN 263
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 265
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 266 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 319
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 302
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 320 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L
Sbjct: 255 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 314
Query: 598 --------GVRGV-VDWRWL--LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R + VD +L L +I K + ++ L SNKL LP+ I +++KL L
Sbjct: 315 PSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLN 374
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ ++L
Sbjct: 375 LSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL157948-2|CAI22426.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 51 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 107
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 108 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 163
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 164 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 542
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 188 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 247
Query: 541 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 248 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 307
Query: 397 YFTISSNELQSLPCSL 350
F S NEL+SLP ++
Sbjct: 308 EFDCSCNELESLPSTI 323
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 99 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 158
Query: 598 --GVRGVVDWRWL-LGPQITKTL-----KL-----LDLTSNKLGHLPKAIWKLEKLVTLK 458
+V R L L KTL KL LDL +N+ G LP+ + +++ L L
Sbjct: 159 PANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELW 218
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++N + LP +IG++ L Y +S N ++++ + C LE + +SSN
Sbjct: 219 MDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSN 268
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 270
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 271 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 324
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 302
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 325 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L
Sbjct: 260 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 319
Query: 598 --------GVRGV-VDWRWL--LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R + VD +L L +I K + ++ L SNKL LP+ I +++KL L
Sbjct: 320 PSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLN 379
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ ++L
Sbjct: 380 LSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AL157948-1|CAI22425.1| 1537|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1537
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 46 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 159 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 542
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 183 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 242
Query: 541 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 243 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 302
Query: 397 YFTISSNELQSLPCSL 350
F S NEL+SLP ++
Sbjct: 303 EFDCSCNELESLPSTI 318
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 94 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 153
Query: 598 --GVRGVVDWRWL-LGPQITKTL-----KL-----LDLTSNKLGHLPKAIWKLEKLVTLK 458
+V R L L KTL KL LDL +N+ G LP+ + +++ L L
Sbjct: 154 PANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELW 213
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++N + LP +IG++ L Y +S N ++++ + C LE + +SSN
Sbjct: 214 MDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSN 263
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 265
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 266 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 319
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 302
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 320 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L
Sbjct: 255 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 314
Query: 598 --------GVRGV-VDWRWL--LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R + VD +L L +I K + ++ L SNKL LP+ I +++KL L
Sbjct: 315 PSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLN 374
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ ++L
Sbjct: 375 LSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>AL117353-1|CAI23423.1| 1495|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 1495
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 51 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 107
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 108 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 163
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 164 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 201
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 542
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 188 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 247
Query: 541 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 248 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 307
Query: 397 YFTISSNELQSLPCSL 350
F S NEL+SLP ++
Sbjct: 308 EFDCSCNELESLPSTI 323
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 99 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 158
Query: 598 --GVRGVVDWRWL-LGPQITKTL-----KL-----LDLTSNKLGHLPKAIWKLEKLVTLK 458
+V R L L KTL KL LDL +N+ G LP+ + +++ L L
Sbjct: 159 PANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELW 218
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++N + LP +IG++ L Y +S N ++++ + C LE + +SSN
Sbjct: 219 MDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSN 268
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 212 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 270
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 271 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 324
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 302
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 325 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 363
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L
Sbjct: 260 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 319
Query: 598 --------GVRGV-VDWRWL--LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R + VD +L L +I K + ++ L SNKL LP+ I +++KL L
Sbjct: 320 PSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLN 379
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ ++L
Sbjct: 380 LSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 411
>AF434715-1|AAL28133.1| 1537|Homo sapiens densin-180 protein.
Length = 1537
Score = 72.1 bits (169), Expect = 2e-12
Identities = 45/158 (28%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 46 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R+ LR + N L++LP S+ + +LE +D+ +N+F
Sbjct: 159 RLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEF 196
Score = 72.1 bits (169), Expect = 2e-12
Identities = 52/136 (38%), Positives = 72/136 (52%), Gaps = 16/136 (11%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR--GVVDWRWLLGPQITKT-- 542
L L LDL NNE +LP ++ NL EL + NN L V + + L+ ++K
Sbjct: 183 LAQLERLDLGNNEFGELPEVLDQIQNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRI 242
Query: 541 ------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L+ L L+SN L LP +I L+KL TLK +DN ++ LP TIG +S L
Sbjct: 243 ETVDMDISGCEALEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLE 302
Query: 397 YFTISSNELQSLPCSL 350
F S NEL+SLP ++
Sbjct: 303 EFDCSCNELESLPSTI 318
Score = 58.8 bits (136), Expect = 2e-08
Identities = 52/170 (30%), Positives = 87/170 (51%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L +S + F +I K L +++ S N I KLP F ++ NL++L+L + L
Sbjct: 94 LKELDISKNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFL 153
Query: 598 --GVRGVVDWRWL-LGPQITKTL-----KL-----LDLTSNKLGHLPKAIWKLEKLVTLK 458
+V R L L KTL KL LDL +N+ G LP+ + +++ L L
Sbjct: 154 PANFGRLVKLRILELRENHLKTLPKSMHKLAQLERLDLGNNEFGELPEVLDQIQNLRELW 213
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++N + LP +IG++ L Y +S N ++++ + C LE + +SSN
Sbjct: 214 MDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSN 263
Score = 57.6 bits (133), Expect = 5e-08
Identities = 47/159 (29%), Positives = 73/159 (45%), Gaps = 1/159 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+ L++ L I LK L LD+S N IE + + L +L L++N L
Sbjct: 207 QNLRELWMDNNALQVLPGSIGKLKMLVYLDMSKNRIETVDMDISGCEALEDLLLSSNML- 265
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + D LL K L L + N+L LP I L L + N + LP+TIG
Sbjct: 266 -QQLPDSIGLL-----KKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESLPSTIG 319
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNKFD 302
+ +LR + N L LP + C+ + + + SNK +
Sbjct: 320 YLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLE 358
Score = 52.4 bits (120), Expect = 2e-06
Identities = 45/152 (29%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L+ L LS L I LLK L L + +N++ LP G ++ L E + N+L
Sbjct: 255 LEDLLLSSNMLQQLPDSIGLLKKLTTLKVDDNQLTMLPNTIGNLSLLEEFDCSCNELESL 314
Query: 598 --------GVRGV-VDWRWL--LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R + VD +L L +I K + ++ L SNKL LP+ I +++KL L
Sbjct: 315 PSTIGYLHSLRTLAVDENFLPELPREIGSCKNVTVMSLRSNKLEFLPEEIGQMQKLRVLN 374
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ ++L
Sbjct: 375 LSDNRLKNLPFSFTKLKELAALWLSDNQSKAL 406
>BC058935-1|AAH58935.1| 239|Homo sapiens LRRC57 protein protein.
Length = 239
Score = 69.3 bits (162), Expect = 1e-11
Identities = 50/164 (30%), Positives = 86/164 (52%), Gaps = 5/164 (3%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+SL L+ KL +I LK L L L+NN + +LP FG+++ L L L+ NQLG
Sbjct: 64 LKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGA- 122
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L PQ+ + L ++DL+ N++ +P ++ +L+ ++ L N N IS++ I
Sbjct: 123 --------LPPQLCSLRHLDVMDLSKNQIRSIPDSVGELQ-VIELNLNQNQISQISVKIS 173
Query: 415 RISTLRYFTISSN--ELQSLPCSLM-QCRLEYIDISSNKFDNKQ 293
L+ + N EL LP S++ ++ + + N F+ K+
Sbjct: 174 CCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKK 217
Score = 67.3 bits (157), Expect = 6e-11
Identities = 45/131 (34%), Positives = 75/131 (57%), Gaps = 2/131 (1%)
Frame = -2
Query: 694 VLDLSNNEIEKLPPEFGRM-ANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTS 518
V L + + + P + ++ +NL + L+NN++ + L+G + T LK L L +
Sbjct: 18 VFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPL----LIG-KFT-LLKSLSLNN 71
Query: 517 NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR 338
NKL LP I L+KL TL N+N + LP+T G++S L+ ++S N+L +LP L R
Sbjct: 72 NKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLR 131
Query: 337 -LEYIDISSNK 308
L+ +D+S N+
Sbjct: 132 HLDVMDLSKNQ 142
Score = 64.1 bits (149), Expect = 5e-10
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 4/148 (2%)
Frame = -2
Query: 739 LCNFRRDIL-LLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWL 566
L F D+ L +L +DLSNN+IE LPP G+ L L L NN+L V
Sbjct: 26 LTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTV--------- 76
Query: 565 LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYF 392
L +I K L+ L L +N L LP +L L TL + N + LP + + L
Sbjct: 77 LPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVM 136
Query: 391 TISSNELQSLPCSLMQCRLEYIDISSNK 308
+S N+++S+P S+ + ++ ++++ N+
Sbjct: 137 DLSKNQIRSIPDSVGELQVIELNLNQNQ 164
Score = 33.1 bits (72), Expect = 1.2
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 2/135 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L++L L+ L L L L LS N++ LPP+ + +L + L+ NQ
Sbjct: 85 KKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQ-- 142
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM--ISRLPAT 422
+R + D L Q+ + L+L N++ + I +L L+ +N +S LP +
Sbjct: 143 IRSIPDSVGEL--QVIE----LNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQS 196
Query: 421 IGRISTLRYFTISSN 377
I S + + N
Sbjct: 197 ILSDSQICLLAVEGN 211
>AK094891-1|BAC04451.1| 239|Homo sapiens protein ( Homo sapiens
cDNA FLJ37572 fis, clone BRCOC2002751, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 239
Score = 69.3 bits (162), Expect = 1e-11
Identities = 50/164 (30%), Positives = 86/164 (52%), Gaps = 5/164 (3%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+SL L+ KL +I LK L L L+NN + +LP FG+++ L L L+ NQLG
Sbjct: 64 LKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGA- 122
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L PQ+ + L ++DL+ N++ +P ++ +L+ ++ L N N IS++ I
Sbjct: 123 --------LPPQLCSLRHLDVMDLSKNQIRSIPDSVGELQ-VIELNLNQNQISQISVKIS 173
Query: 415 RISTLRYFTISSN--ELQSLPCSLM-QCRLEYIDISSNKFDNKQ 293
L+ + N EL LP S++ ++ + + N F+ K+
Sbjct: 174 CCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKK 217
Score = 67.3 bits (157), Expect = 6e-11
Identities = 45/131 (34%), Positives = 75/131 (57%), Gaps = 2/131 (1%)
Frame = -2
Query: 694 VLDLSNNEIEKLPPEFGRM-ANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTS 518
V L + + + P + ++ +NL + L+NN++ + L+G + T LK L L +
Sbjct: 18 VFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPL----LIG-KFT-LLKSLSLNN 71
Query: 517 NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR 338
NKL LP I L+KL TL N+N + LP+T G++S L+ ++S N+L +LP L R
Sbjct: 72 NKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLR 131
Query: 337 -LEYIDISSNK 308
L+ +D+S N+
Sbjct: 132 HLDVMDLSKNQ 142
Score = 64.1 bits (149), Expect = 5e-10
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 4/148 (2%)
Frame = -2
Query: 739 LCNFRRDIL-LLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWL 566
L F D+ L +L +DLSNN+IE LPP G+ L L L NN+L V
Sbjct: 26 LTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTV--------- 76
Query: 565 LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYF 392
L +I K L+ L L +N L LP +L L TL + N + LP + + L
Sbjct: 77 LPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVM 136
Query: 391 TISSNELQSLPCSLMQCRLEYIDISSNK 308
+S N+++S+P S+ + ++ ++++ N+
Sbjct: 137 DLSKNQIRSIPDSVGELQVIELNLNQNQ 164
Score = 33.1 bits (72), Expect = 1.2
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 2/135 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L++L L+ L L L L LS N++ LPP+ + +L + L+ NQ
Sbjct: 85 KKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQ-- 142
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM--ISRLPAT 422
+R + D L Q+ + L+L N++ + I +L L+ +N +S LP +
Sbjct: 143 IRSIPDSVGEL--QVIE----LNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQS 196
Query: 421 IGRISTLRYFTISSN 377
I S + + N
Sbjct: 197 ILSDSQICLLAVEGN 211
>AK094131-1|BAC04294.1| 239|Homo sapiens (EC 2.4.1.101). protein.
Length = 239
Score = 69.3 bits (162), Expect = 1e-11
Identities = 50/164 (30%), Positives = 86/164 (52%), Gaps = 5/164 (3%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+SL L+ KL +I LK L L L+NN + +LP FG+++ L L L+ NQLG
Sbjct: 64 LKSLSLNNNKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGA- 122
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L PQ+ + L ++DL+ N++ +P ++ +L+ ++ L N N IS++ I
Sbjct: 123 --------LPPQLCSLRHLDVMDLSKNQIRSIPDSVGELQ-VIELNLNQNQISQISVKIS 173
Query: 415 RISTLRYFTISSN--ELQSLPCSLM-QCRLEYIDISSNKFDNKQ 293
L+ + N EL LP S++ ++ + + N F+ K+
Sbjct: 174 CCPRLKILRLEENCLELSMLPQSILSDSQICLLAVEGNLFEIKK 217
Score = 67.3 bits (157), Expect = 6e-11
Identities = 45/131 (34%), Positives = 75/131 (57%), Gaps = 2/131 (1%)
Frame = -2
Query: 694 VLDLSNNEIEKLPPEFGRM-ANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTS 518
V L + + + P + ++ +NL + L+NN++ + L+G + T LK L L +
Sbjct: 18 VFQLKDRGLTEFPADLQKLTSNLRTIDLSNNKIESLPPL----LIG-KFT-LLKSLSLNN 71
Query: 517 NKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR 338
NKL LP I L+KL TL N+N + LP+T G++S L+ ++S N+L +LP L R
Sbjct: 72 NKLTVLPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLR 131
Query: 337 -LEYIDISSNK 308
L+ +D+S N+
Sbjct: 132 HLDVMDLSKNQ 142
Score = 64.1 bits (149), Expect = 5e-10
Identities = 47/148 (31%), Positives = 75/148 (50%), Gaps = 4/148 (2%)
Frame = -2
Query: 739 LCNFRRDIL-LLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWL 566
L F D+ L +L +DLSNN+IE LPP G+ L L L NN+L V
Sbjct: 26 LTEFPADLQKLTSNLRTIDLSNNKIESLPPLLIGKFTLLKSLSLNNNKLTV--------- 76
Query: 565 LGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYF 392
L +I K L+ L L +N L LP +L L TL + N + LP + + L
Sbjct: 77 LPDEICNLKKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVM 136
Query: 391 TISSNELQSLPCSLMQCRLEYIDISSNK 308
+S N+++S+P S+ + ++ ++++ N+
Sbjct: 137 DLSKNQIRSIPDSVGELQVIELNLNQNQ 164
Score = 33.1 bits (72), Expect = 1.2
Identities = 34/135 (25%), Positives = 60/135 (44%), Gaps = 2/135 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L++L L+ L L L L LS N++ LPP+ + +L + L+ NQ
Sbjct: 85 KKLETLSLNNNHLRELPSTFGQLSALKTLSLSGNQLGALPPQLCSLRHLDVMDLSKNQ-- 142
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM--ISRLPAT 422
+R + D L Q+ + L+L N++ + I +L L+ +N +S LP +
Sbjct: 143 IRSIPDSVGEL--QVIE----LNLNQNQISQISVKISCCPRLKILRLEENCLELSMLPQS 196
Query: 421 IGRISTLRYFTISSN 377
I S + + N
Sbjct: 197 ILSDSQICLLAVEGN 211
>BC126464-1|AAI26465.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/137 (30%), Positives = 69/137 (50%), Gaps = 1/137 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L LD+S N IE + NL +L L++N L + + + LL K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSL--QQLPETIGLL-----KNITTL 281
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 349 MQCR-LEYIDISSNKFD 302
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 2/138 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGLLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 526 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 350
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 349 -MQCRLEYIDISSNKFDN 299
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 51.6 bits (118), Expect = 3e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 598 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGLLKNITTLK 282
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 344
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 51.6 bits (118), Expect = 3e-06
Identities = 43/152 (28%), Positives = 72/152 (47%), Gaps = 16/152 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
LQ L LS L I LLK++ L + N++ LP G + ++ EL + N++
Sbjct: 255 LQDLLLSSNSLQQLPETIGLLKNITTLKIDENQLMYLPDSIGGLISVEELDCSFNEVEAL 314
Query: 598 --------GVRG-VVDWRWL--LGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+R D +L L P+I K + +L L SNKL LP+ + ++KL +
Sbjct: 315 PSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMGDMQKLKVIN 374
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+DN + LP + ++ L +S N+ + L
Sbjct: 375 LSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
>BC115012-1|AAI15013.1| 1371|Homo sapiens erbb2 interacting protein
protein.
Length = 1371
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 5e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 2/138 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPEPIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 526 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 350
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 349 -MQCRLEYIDISSNKFDN 299
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 2e-07
Identities = 42/138 (30%), Positives = 67/138 (48%), Gaps = 2/138 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGP-QITKTLKL 533
LK L LD+S N IE + NL +L L++N L + L P K +
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSL--------QQLPEPIGSLKNITT 280
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L + N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP
Sbjct: 281 LKIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPE 340
Query: 352 LMQCR-LEYIDISSNKFD 302
+ + + + + SNK +
Sbjct: 341 IGSWKNITVLFLHSNKLE 358
Score = 52.0 bits (119), Expect = 2e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 598 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPEPIGSLKNITTLK 282
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 344
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 50.8 bits (116), Expect = 5e-06
Identities = 33/110 (30%), Positives = 52/110 (47%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 512
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 511 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
>BC050692-1|AAH50692.1| 633|Homo sapiens ERBB2IP protein protein.
Length = 633
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 5e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 2/138 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 526 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 350
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 349 -MQCRLEYIDISSNKFDN 299
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 1/137 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L LD+S N IE + NL +L L++N L +G K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPET-----IGS--LKNITTL 281
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 349 MQCR-LEYIDISSNKFD 302
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 598 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLK 282
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 344
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 50.8 bits (116), Expect = 5e-06
Identities = 33/110 (30%), Positives = 52/110 (47%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 512
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 511 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
>AF276423-1|AAK69431.1| 1412|Homo sapiens densin-180-like protein
protein.
Length = 1412
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 5e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 2/138 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 526 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 350
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 349 -MQCRLEYIDISSNKFDN 299
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 1/137 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L LD+S N IE + NL +L L++N L +G K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPET-----IGS--LKNITTL 281
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 349 MQCR-LEYIDISSNKFD 302
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 598 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLK 282
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 344
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 50.8 bits (116), Expect = 5e-06
Identities = 33/110 (30%), Positives = 52/110 (47%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 512
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 511 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
>AF271734-1|AAP88018.1| 1601|Homo sapiens SCRIB1 variant N1 protein.
Length = 1601
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/137 (31%), Positives = 67/137 (48%), Gaps = 1/137 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L +L L LS+NEI++LPPE L EL ++ N + + + + K L++
Sbjct: 29 LLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRND--IPEIPE-----SIKFCKALEIA 81
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
D + N L LP +L L L ND + LP +G ++ L + N L+SLP SL
Sbjct: 82 DFSGNPLSRLPDGFTQLRSLAHLALNDVSLQALPGDVGNLANLVTLELRENLLKSLPASL 141
Query: 349 -MQCRLEYIDISSNKFD 302
+LE +D+ N +
Sbjct: 142 SFLVKLEQLDLGGNDLE 158
Score = 58.0 bits (134), Expect = 4e-08
Identities = 40/125 (32%), Positives = 59/125 (47%), Gaps = 2/125 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL- 533
L L LDL N++E LP G + NL EL L NQL L P++ +L
Sbjct: 144 LVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSA---------LPPELGNLRRLV 194
Query: 532 -LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
LD++ N+L LP + L L L + N++ RLP IG++ L + N L +
Sbjct: 195 CLDVSENRLEELPAELGGLVLLTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTE 254
Query: 355 SLMQC 341
++ C
Sbjct: 255 AIGDC 259
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/140 (30%), Positives = 68/140 (48%), Gaps = 1/140 (0%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
I K L + D S N + +LP F ++ +L+ HLA N + ++ + L +T
Sbjct: 72 IKFCKALEIADFSGNPLSRLPDGFTQLRSLA--HLALNDVSLQALPGDVGNLANLVT--- 126
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
L+L N L LP ++ L KL L N + LP T+G + LR + N+L +LP
Sbjct: 127 --LELRENLLKSLPASLSFLVKLEQLDLGGNDLEVLPDTLGALPNLRELWLDRNQLSALP 184
Query: 358 CSLMQC-RLEYIDISSNKFD 302
L RL +D+S N+ +
Sbjct: 185 PELGNLRRLVCLDVSENRLE 204
Score = 52.4 bits (120), Expect = 2e-06
Identities = 49/165 (29%), Positives = 72/165 (43%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L L LS L I LK L++L + N + ++ G NLSEL L N L
Sbjct: 216 LTDLLLSQNLLRRLPDGIGQLKQLSILKVDQNRLCEVTEAIGDCENLSELILTENLL--- 272
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ LG ++TK L L++ N L LP I L L DN ++ LP +
Sbjct: 273 --MALPRSLG-KLTK-LTNLNVDRNHLEALPPEIGGCVALSVLSLRDNRLAVLPPELAHT 328
Query: 409 STLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTSD 275
+ L ++ N LQSLP +L L+ + ++ N+ T D
Sbjct: 329 TELHVLDVAGNRLQSLPFALTHLNLKALWLAENQAQPMLRFQTED 373
Score = 35.5 bits (78), Expect = 0.22
Identities = 20/60 (33%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Frame = -2
Query: 487 WKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++L L L +DN I RLP + L +S N++ +P S+ C+ LE D S N
Sbjct: 27 FRLLNLRKLGLSDNEIQRLPPEVANFMQLVELDVSRNDIPEIPESIKFCKALEIADFSGN 86
>AF263744-1|AAF77048.1| 1371|Homo sapiens erbb2-interacting protein
ERBIN protein.
Length = 1371
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 5e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 2/138 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 526 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 350
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 349 -MQCRLEYIDISSNKFDN 299
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 1/137 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L LD+S N IE + NL +L L++N L +G K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPET-----IGS--LKNITTL 281
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 349 MQCR-LEYIDISSNKFD 302
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 598 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLK 282
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 344
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 50.8 bits (116), Expect = 5e-06
Identities = 33/110 (30%), Positives = 52/110 (47%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 512
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 511 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
>AB033051-1|BAA86539.2| 1371|Homo sapiens KIAA1225 protein protein.
Length = 1371
Score = 68.1 bits (159), Expect = 3e-11
Identities = 43/158 (27%), Positives = 81/158 (51%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
G+ ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFG 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 5e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 2/138 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 526 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 350
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 349 -MQCRLEYIDISSNKFDN 299
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 1/137 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L LD+S N IE + NL +L L++N L +G K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPET-----IGS--LKNITTL 281
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 349 MQCR-LEYIDISSNKFD 302
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 598 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLK 282
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 344
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 50.8 bits (116), Expect = 5e-06
Identities = 33/110 (30%), Positives = 52/110 (47%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 512
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 511 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
>BC024159-1|AAH24159.2| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 66.9 bits (156), Expect = 8e-11
Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+SLY S KL + + L+ L LD+S N I +P E G + NL LH+ N++
Sbjct: 706 KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVD 765
Query: 595 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
+ L Q+ K +KL L+L N + LP+ + +L +L L+ N + RLPA
Sbjct: 766 I---------LPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQ 816
Query: 421 IGRISTLRY--FTISSNELQSLPCSLMQCRLEYIDI 320
+G+ L+ + + +LP + + + I+I
Sbjct: 817 LGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINI 852
Score = 65.3 bits (152), Expect = 2e-10
Identities = 46/147 (31%), Positives = 72/147 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L L L K+ I +K+L L SNN++E LP + L L ++ N +
Sbjct: 683 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 742
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + +G + + L+ L +T NK+ LPK ++K KL TL N I+ LP +G
Sbjct: 743 MIPIE-----IG--LLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVG 795
Query: 415 RISTLRYFTISSNELQSLPCSLMQCRL 335
++S L + N L LP L QCR+
Sbjct: 796 QLSQLTQLELKGNCLDRLPAQLGQCRM 822
>AY358874-1|AAQ89233.1| 501|Homo sapiens LRRC5 protein.
Length = 501
Score = 66.9 bits (156), Expect = 8e-11
Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+SLY S KL + + L+ L LD+S N I +P E G + NL LH+ N++
Sbjct: 349 KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVD 408
Query: 595 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
+ L Q+ K +KL L+L N + LP+ + +L +L L+ N + RLPA
Sbjct: 409 I---------LPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQ 459
Query: 421 IGRISTLRY--FTISSNELQSLPCSLMQCRLEYIDI 320
+G+ L+ + + +LP + + + I+I
Sbjct: 460 LGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINI 495
Score = 65.3 bits (152), Expect = 2e-10
Identities = 46/147 (31%), Positives = 72/147 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L L L K+ I +K+L L SNN++E LP + L L ++ N +
Sbjct: 326 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 385
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + +G + + L+ L +T NK+ LPK ++K KL TL N I+ LP +G
Sbjct: 386 MIPIE-----IG--LLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVG 438
Query: 415 RISTLRYFTISSNELQSLPCSLMQCRL 335
++S L + N L LP L QCR+
Sbjct: 439 QLSQLTQLELKGNCLDRLPAQLGQCRM 465
>AL391497-3|CAH72226.1| 858|Homo sapiens leucine rich repeat
containing 8 family, member D protein.
Length = 858
Score = 66.9 bits (156), Expect = 8e-11
Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+SLY S KL + + L+ L LD+S N I +P E G + NL LH+ N++
Sbjct: 706 KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVD 765
Query: 595 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
+ L Q+ K +KL L+L N + LP+ + +L +L L+ N + RLPA
Sbjct: 766 I---------LPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQ 816
Query: 421 IGRISTLRY--FTISSNELQSLPCSLMQCRLEYIDI 320
+G+ L+ + + +LP + + + I+I
Sbjct: 817 LGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINI 852
Score = 65.3 bits (152), Expect = 2e-10
Identities = 46/147 (31%), Positives = 72/147 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L L L K+ I +K+L L SNN++E LP + L L ++ N +
Sbjct: 683 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 742
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + +G + + L+ L +T NK+ LPK ++K KL TL N I+ LP +G
Sbjct: 743 MIPIE-----IG--LLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVG 795
Query: 415 RISTLRYFTISSNELQSLPCSLMQCRL 335
++S L + N L LP L QCR+
Sbjct: 796 QLSQLTQLELKGNCLDRLPAQLGQCRM 822
>AK001332-1|BAA91631.1| 682|Homo sapiens protein ( Homo sapiens
cDNA FLJ10470 fis, clone NT2RP2000032, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 682
Score = 66.9 bits (156), Expect = 8e-11
Identities = 46/156 (29%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+SLY S KL + + L+ L LD+S N I +P E G + NL LH+ N++
Sbjct: 530 KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQNLQHLHITGNKVD 589
Query: 595 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
+ L Q+ K +KL L+L N + LP+ + +L +L L+ N + RLPA
Sbjct: 590 I---------LPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQ 640
Query: 421 IGRISTLRY--FTISSNELQSLPCSLMQCRLEYIDI 320
+G+ L+ + + +LP + + + I+I
Sbjct: 641 LGQCRMLKKSGLVVEDHLFDTLPLEVKEALNQDINI 676
Score = 65.3 bits (152), Expect = 2e-10
Identities = 46/147 (31%), Positives = 72/147 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L L L K+ I +K+L L SNN++E LP + L L ++ N +
Sbjct: 507 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 566
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + +G + + L+ L +T NK+ LPK ++K KL TL N I+ LP +G
Sbjct: 567 MIPIE-----IG--LLQNLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVG 619
Query: 415 RISTLRYFTISSNELQSLPCSLMQCRL 335
++S L + N L LP L QCR+
Sbjct: 620 QLSQLTQLELKGNCLDRLPAQLGQCRM 646
>BC115015-1|AAI15016.1| 1367|Homo sapiens ERBB2IP protein protein.
Length = 1367
Score = 65.3 bits (152), Expect = 2e-10
Identities = 42/158 (26%), Positives = 80/158 (50%), Gaps = 1/158 (0%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+TL+ LYL ++ + + + L L L +N++ LP + NL EL ++ N
Sbjct: 46 KTLEELYLDANQIEELPKQLFNCQSLHKLSLPDNDLTTLPASIANLINLRELDVSKN--- 102
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
G+ ++ + + K L +++ + N + LP +L L L ND + LPA
Sbjct: 103 --GIQEFPENI--KNCKVLTIVEASVNPISKLPDGFSQLLNLTQLYLNDAFLEFLPANFD 158
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNKF 305
R++ L+ + N+L+ LP ++ + +LE +D+ SN+F
Sbjct: 159 RLTKLQILELRENQLKMLPKTMNRLTQLERLDLGSNEF 196
Score = 57.6 bits (133), Expect = 5e-08
Identities = 43/138 (31%), Positives = 77/138 (55%), Gaps = 2/138 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
++L L LS+N +++LP G + N++ L + NQL + D +G I+ ++ LD
Sbjct: 253 ENLQDLLLSSNSLQQLPETIGSLKNITTLKIDENQLMY--LPD---SIGGLIS--VEELD 305
Query: 526 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL- 350
+ N++ LP +I +L L T A+ N + +LP IG + + SN+L++LP +
Sbjct: 306 CSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSWKNITVLFLHSNKLETLPEEMG 365
Query: 349 -MQCRLEYIDISSNKFDN 299
MQ +L+ I++S N+ N
Sbjct: 366 DMQ-KLKVINLSDNRLKN 382
Score = 55.6 bits (128), Expect = 2e-07
Identities = 41/137 (29%), Positives = 66/137 (48%), Gaps = 1/137 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
LK L LD+S N IE + NL +L L++N L +G K + L
Sbjct: 229 LKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPET-----IGS--LKNITTL 281
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+ N+L +LP +I L + L + N + LP++IG+++ LR F N LQ LP +
Sbjct: 282 KIDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEI 341
Query: 349 MQCR-LEYIDISSNKFD 302
+ + + + SNK +
Sbjct: 342 GSWKNITVLFLHSNKLE 358
Score = 52.4 bits (120), Expect = 2e-06
Identities = 46/158 (29%), Positives = 75/158 (47%), Gaps = 16/158 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
LQ L L +L + + L L LDL +NE ++P +++ L E + N+L
Sbjct: 163 LQILELRENQLKMLPKTMNRLTQLERLDLGSNEFTEVPEVLEQLSGLKEFWMDANRLTFI 222
Query: 598 -GVRGVVDWRWLL------------GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
G G + L G + L+ L L+SN L LP+ I L+ + TLK
Sbjct: 223 PGFIGSLKQLTYLDVSKNNIEMVEEGISTCENLQDLLLSSNSLQQLPETIGSLKNITTLK 282
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 344
++N + LP +IG + ++ S NE+++LP S+ Q
Sbjct: 283 IDENQLMYLPDSIGGLISVEELDCSFNEVEALPSSIGQ 320
Score = 50.8 bits (116), Expect = 5e-06
Identities = 33/110 (30%), Positives = 52/110 (47%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 512
LD S NE+E LP G++ NL +N L W K + +L L SNK
Sbjct: 304 LDCSFNEVEALPSSIGQLTNLRTFAADHNYLQQLPPEIGSW-------KNITVLFLHSNK 356
Query: 511 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L LP+ + ++KL + +DN + LP + ++ L +S N+ + L
Sbjct: 357 LETLPEEMGDMQKLKVINLSDNRLKNLPFSFTKLQQLTAMWLSDNQSKPL 406
>BC014904-1|AAH14904.1| 893|Homo sapiens leucine-rich repeats and
death domain containing protein.
Length = 893
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/144 (36%), Positives = 70/144 (48%), Gaps = 1/144 (0%)
Frame = -2
Query: 739 LCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLG 560
L N + L HLA LDLS N +E LP +M L L L++N L + LG
Sbjct: 114 LTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLS-----ELPEALG 168
Query: 559 PQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 380
L L +T N+L LP A+ L L L + N++ LP IG + +L ++S
Sbjct: 169 --ALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLAS 226
Query: 379 NELQSLPCSLMQCR-LEYIDISSN 311
N LQSLP SL R L + + SN
Sbjct: 227 NRLQSLPASLAGLRSLRLLVLHSN 250
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 2/145 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L +L LS L + L L L +++N ++ LPP G ++ L L L+ N L
Sbjct: 148 RGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLD 207
Query: 595 VRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
L P+I +L L+L SN+L LP ++ L L L + N+++ +PA
Sbjct: 208 T---------LPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPAD 258
Query: 421 IGRISTLRYFTISSNELQSLPCSLM 347
+ R+ L + N+L+ LP L+
Sbjct: 259 LARLPLLTRLDLRDNQLRDLPPELL 283
Score = 56.0 bits (129), Expect = 1e-07
Identities = 43/138 (31%), Positives = 68/138 (49%), Gaps = 1/138 (0%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
+L ++ L L LS+N + +LP G + L+ L + +N+L LG TL
Sbjct: 144 VLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPA-----LGA--LSTL 196
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
+ LDL+ N L LP I L L+ L N + LPA++ + +LR + SN L S+P
Sbjct: 197 QRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVP 256
Query: 358 CSLMQC-RLEYIDISSNK 308
L + L +D+ N+
Sbjct: 257 ADLARLPLLTRLDLRDNQ 274
>AF274972-1|AAG13461.1| 910|Homo sapiens PIDD protein.
Length = 910
Score = 65.3 bits (152), Expect = 2e-10
Identities = 52/144 (36%), Positives = 70/144 (48%), Gaps = 1/144 (0%)
Frame = -2
Query: 739 LCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLG 560
L N + L HLA LDLS N +E LP +M L L L++N L + LG
Sbjct: 114 LTNLPAGLSGLAHLAHLDLSFNSLETLPACVLQMRGLGALLLSHNCLS-----ELPEALG 168
Query: 559 PQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 380
L L +T N+L LP A+ L L L + N++ LP IG + +L ++S
Sbjct: 169 --ALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLDTLPPEIGGLGSLLELNLAS 226
Query: 379 NELQSLPCSLMQCR-LEYIDISSN 311
N LQSLP SL R L + + SN
Sbjct: 227 NRLQSLPASLAGLRSLRLLVLHSN 250
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 2/145 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L +L LS L + L L L +++N ++ LPP G ++ L L L+ N L
Sbjct: 148 RGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLD 207
Query: 595 VRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
L P+I +L L+L SN+L LP ++ L L L + N+++ +PA
Sbjct: 208 T---------LPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPAD 258
Query: 421 IGRISTLRYFTISSNELQSLPCSLM 347
+ R+ L + N+L+ LP L+
Sbjct: 259 LARLPLLTRLDLRDNQLRDLPPELL 283
Score = 56.0 bits (129), Expect = 1e-07
Identities = 43/138 (31%), Positives = 68/138 (49%), Gaps = 1/138 (0%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
+L ++ L L LS+N + +LP G + L+ L + +N+L LG TL
Sbjct: 144 VLQMRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPA-----LGA--LSTL 196
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
+ LDL+ N L LP I L L+ L N + LPA++ + +LR + SN L S+P
Sbjct: 197 QRLDLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVP 256
Query: 358 CSLMQC-RLEYIDISSNK 308
L + L +D+ N+
Sbjct: 257 ADLARLPLLTRLDLRDNQ 274
>U80184-1|AAC02796.1| 1269|Homo sapiens FLII protein.
Length = 1269
Score = 64.9 bits (151), Expect = 3e-10
Identities = 48/158 (30%), Positives = 86/158 (54%), Gaps = 5/158 (3%)
Frame = -2
Query: 769 LQSLYLSGLKLC--NFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
LQ+L+L + N + L +LA +DLS N++ ++P + +L L+L++NQ+
Sbjct: 200 LQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIT 259
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS--RLPAT 422
+ +W+ ++ L+L+ N+L LP AI KL KL L N N + LP+
Sbjct: 260 ELSLCIDQWV-------HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSG 312
Query: 421 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
IG+++ L F ++N L+ +P SL +C +L + ++ N
Sbjct: 313 IGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKN 350
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L LDLS N +E LPP+ R+ +L L L N L R L +TL L
Sbjct: 150 LTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPL---LHAQLRQLPAMTALQTLHLR 206
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
T +LP ++ L L + + N ++R+P + + +LR +SSN++ L +
Sbjct: 207 S-TQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCI 265
Query: 349 MQ-CRLEYIDISSNK 308
Q +E +++S N+
Sbjct: 266 DQWVHVETLNLSRNQ 280
>U01184-1|AAC03568.1| 1268|Homo sapiens flightless-I homolog
protein.
Length = 1268
Score = 64.9 bits (151), Expect = 3e-10
Identities = 48/158 (30%), Positives = 86/158 (54%), Gaps = 5/158 (3%)
Frame = -2
Query: 769 LQSLYLSGLKLC--NFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
LQ+L+L + N + L +LA +DLS N++ ++P + +L L+L++NQ+
Sbjct: 199 LQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIT 258
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS--RLPAT 422
+ +W+ ++ L+L+ N+L LP AI KL KL L N N + LP+
Sbjct: 259 ELSLCIDQWV-------HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSG 311
Query: 421 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
IG+++ L F ++N L+ +P SL +C +L + ++ N
Sbjct: 312 IGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKN 349
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L LDLS N +E LPP+ R+ +L L L N L R L +TL L
Sbjct: 149 LTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPL---LHAQLRQLPAMTALQTLHLR 205
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
T +LP ++ L L + + N ++R+P + + +LR +SSN++ L +
Sbjct: 206 S-TQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCI 264
Query: 349 MQ-CRLEYIDISSNK 308
Q +E +++S N+
Sbjct: 265 DQWVHVETLNLSRNQ 279
>BC025300-1|AAH25300.1| 1269|Homo sapiens flightless I homolog
(Drosophila) protein.
Length = 1269
Score = 64.9 bits (151), Expect = 3e-10
Identities = 48/158 (30%), Positives = 86/158 (54%), Gaps = 5/158 (3%)
Frame = -2
Query: 769 LQSLYLSGLKLC--NFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
LQ+L+L + N + L +LA +DLS N++ ++P + +L L+L++NQ+
Sbjct: 200 LQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIT 259
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS--RLPAT 422
+ +W+ ++ L+L+ N+L LP AI KL KL L N N + LP+
Sbjct: 260 ELSLCIDQWV-------HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSG 312
Query: 421 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
IG+++ L F ++N L+ +P SL +C +L + ++ N
Sbjct: 313 IGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKN 350
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L LDLS N +E LPP+ R+ +L L L N L R L +TL L
Sbjct: 150 LTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPL---LHAQLRQLPAMTALQTLHLR 206
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
T +LP ++ L L + + N ++R+P + + +LR +SSN++ L +
Sbjct: 207 S-TQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCI 265
Query: 349 MQ-CRLEYIDISSNK 308
Q +E +++S N+
Sbjct: 266 DQWVHVETLNLSRNQ 280
>BC008586-1|AAH08586.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/171 (29%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV- 593
L L +S KL + D+ LL L VLD+ +N++ LP + NL +L++++N+L +
Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKIL 143
Query: 592 -RGVVDWR-----WLLGPQIT---------KTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+ + R +L ++T L+ LDL++N L +P + L LV L
Sbjct: 144 PEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLN 203
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 308
+ N + LPA I R+ L++ +SN L+++P L LE + + NK
Sbjct: 204 LSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNK 254
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 4/146 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
LQ L +S KL +I L++L L L +NE+ + F +++NL +L L+NN L
Sbjct: 130 LQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTV 189
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+L L+L+SN+L LP I ++++L L N N++ +P + +
Sbjct: 190 PA-------SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGM 242
Query: 409 STLRYFTISSNELQSLP----CSLMQ 344
+L + N+L+ LP CSL++
Sbjct: 243 ESLELLYLRRNKLRFLPEFPSCSLLK 268
Score = 57.6 bits (133), Expect = 5e-08
Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 593
+L L LS +L + +I +K L LD ++N +E +PPE M +L L+L N+L
Sbjct: 198 SLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL-- 255
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIG 416
R+L LK L + N++ L K L ++ L DN + +P I
Sbjct: 256 ------RFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII 309
Query: 415 RISTLRYFTISSNELQSLPCSLMQCRLEYIDISSN 311
+ +L +S+N++ SLP SL L+++ + N
Sbjct: 310 LLRSLERLDLSNNDISSLPYSLGNLHLKFLALEGN 344
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 18/173 (10%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL- 599
R L+ LYL +L L +L LDLSNN + +P F +++L L+L++N+L
Sbjct: 151 RNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELK 210
Query: 598 ----GVRGVVDWRWL---------LGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 464
+ + + L + P++ ++L+LL L NKL LP+ L
Sbjct: 211 SLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKE 269
Query: 463 LKANDNMISRLPAT-IGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L +N I L A + ++++ + N+L+S+P ++ R LE +D+S+N
Sbjct: 270 LHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNN 322
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/118 (27%), Positives = 56/118 (47%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 512
L+LS + ++P R+ N+ AN L G + RW +TK + +++NK
Sbjct: 41 LNLSGRNLSEVPQCVWRI-NVDIPEEANQNLSF-GATE-RWWEQTDLTKLI----ISNNK 93
Query: 511 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR 338
L L + L L L +DN ++ LP+ I + L+ +S N+L+ LP + R
Sbjct: 94 LQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLR 151
Score = 42.3 bits (95), Expect = 0.002
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Frame = -2
Query: 553 ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNE 374
+ + L LDL +N L LP+ + L +L T+ + N LP + RI TL IS+N+
Sbjct: 470 VLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 529
Query: 373 LQSLPCSLMQC--RLEYIDISSN 311
+ S+ M+ L +D+ +N
Sbjct: 530 VGSVDPQKMKMMENLTTLDLQNN 552
Score = 37.5 bits (83), Expect = 0.054
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
TL+++ +S ++ + + + ++++L LDL NN++ ++PPE G NL L L N
Sbjct: 519 TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFR 578
Query: 595 V 593
V
Sbjct: 579 V 579
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/88 (29%), Positives = 43/88 (48%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L ++LS N + LP R+ L + ++NNQ+ G VD + + ++ + L L
Sbjct: 494 LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQV---GSVDPQKM---KMMENLTTL 547
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDN 446
DL +N L +P + L TL + N
Sbjct: 548 DLQNNDLLQIPPELGNCVNLRTLLLDGN 575
>BC003407-1|AAH03407.2| 581|Homo sapiens LRRC40 protein protein.
Length = 581
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/171 (29%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV- 593
L L +S KL + D+ LL L VLD+ +N++ LP + NL +L++++N+L +
Sbjct: 63 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKIL 122
Query: 592 -RGVVDWR-----WLLGPQIT---------KTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+ + R +L ++T L+ LDL++N L +P + L LV L
Sbjct: 123 PEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLN 182
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 308
+ N + LPA I R+ L++ +SN L+++P L LE + + NK
Sbjct: 183 LSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNK 233
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 4/146 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
LQ L +S KL +I L++L L L +NE+ + F +++NL +L L+NN L
Sbjct: 109 LQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTV 168
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+L L+L+SN+L LP I ++++L L N N++ +P + +
Sbjct: 169 PA-------SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGM 221
Query: 409 STLRYFTISSNELQSLP----CSLMQ 344
+L + N+L+ LP CSL++
Sbjct: 222 ESLELLYLRRNKLRFLPEFPSCSLLK 247
Score = 57.6 bits (133), Expect = 5e-08
Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 593
+L L LS +L + +I +K L LD ++N +E +PPE M +L L+L N+L
Sbjct: 177 SLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL-- 234
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIG 416
R+L LK L + N++ L K L ++ L DN + +P I
Sbjct: 235 ------RFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII 288
Query: 415 RISTLRYFTISSNELQSLPCSLMQCRLEYIDISSN 311
+ +L +S+N++ SLP SL L+++ + N
Sbjct: 289 LLRSLERLDLSNNDISSLPYSLGNLHLKFLALEGN 323
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 18/173 (10%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL- 599
R L+ LYL +L L +L LDLSNN + +P F +++L L+L++N+L
Sbjct: 130 RNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELK 189
Query: 598 ----GVRGVVDWRWL---------LGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 464
+ + + L + P++ ++L+LL L NKL LP+ L
Sbjct: 190 SLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKE 248
Query: 463 LKANDNMISRLPAT-IGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L +N I L A + ++++ + N+L+S+P ++ R LE +D+S+N
Sbjct: 249 LHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNN 301
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/118 (27%), Positives = 56/118 (47%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 512
L+LS + ++P R+ N+ AN L G + RW +TK + +++NK
Sbjct: 20 LNLSGRNLSEVPQCVWRI-NVDIPEEANQNLSF-GATE-RWWEQTDLTKLI----ISNNK 72
Query: 511 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR 338
L L + L L L +DN ++ LP+ I + L+ +S N+L+ LP + R
Sbjct: 73 LQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLR 130
Score = 42.3 bits (95), Expect = 0.002
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Frame = -2
Query: 553 ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNE 374
+ + L LDL +N L LP+ + L +L T+ + N LP + RI TL IS+N+
Sbjct: 449 VLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 508
Query: 373 LQSLPCSLMQC--RLEYIDISSN 311
+ S+ M+ L +D+ +N
Sbjct: 509 VGSVDPQKMKMMENLTTLDLQNN 531
Score = 37.5 bits (83), Expect = 0.054
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
TL+++ +S ++ + + + ++++L LDL NN++ ++PPE G NL L L N
Sbjct: 498 TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFR 557
Query: 595 V 593
V
Sbjct: 558 V 558
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/88 (29%), Positives = 43/88 (48%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L ++LS N + LP R+ L + ++NNQ+ G VD + + ++ + L L
Sbjct: 473 LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQV---GSVDPQKM---KMMENLTTL 526
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDN 446
DL +N L +P + L TL + N
Sbjct: 527 DLQNNDLLQIPPELGNCVNLRTLLLDGN 554
>AL359880-1|CAH70792.1| 734|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 1 protein.
Length = 734
Score = 64.9 bits (151), Expect = 3e-10
Identities = 48/149 (32%), Positives = 75/149 (50%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LS +L ++ L +L+L +N I +P + L+ L+L+ NQL
Sbjct: 104 LSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPAC-- 161
Query: 574 RWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
L G LK+L ++NKLG LP+ I +L++L+ L + N I+ LP IG++ +LR
Sbjct: 162 --LCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRE 215
Query: 394 FTISSNELQSLPCSLMQCRLEYIDISSNK 308
+ N L+ LP L+ L D S NK
Sbjct: 216 LNVRRNYLKVLPQELVDLSLVKFDFSCNK 244
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/85 (29%), Positives = 41/85 (48%)
Frame = -2
Query: 562 GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTIS 383
G ++ T++ DL+ N+L +P + L L N I +P I + L Y +S
Sbjct: 93 GHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLS 151
Query: 382 SNELQSLPCSLMQCRLEYIDISSNK 308
N+L +LP L L+ + S+NK
Sbjct: 152 RNQLSALPACLCGLPLKVLIASNNK 176
>AL353771-3|CAI22332.1| 602|Homo sapiens leucine rich repeat
containing 40 protein.
Length = 602
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/171 (29%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV- 593
L L +S KL + D+ LL L VLD+ +N++ LP + NL +L++++N+L +
Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKIL 143
Query: 592 -RGVVDWR-----WLLGPQIT---------KTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+ + R +L ++T L+ LDL++N L +P + L LV L
Sbjct: 144 PEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLN 203
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 308
+ N + LPA I R+ L++ +SN L+++P L LE + + NK
Sbjct: 204 LSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNK 254
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 4/146 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
LQ L +S KL +I L++L L L +NE+ + F +++NL +L L+NN L
Sbjct: 130 LQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTV 189
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+L L+L+SN+L LP I ++++L L N N++ +P + +
Sbjct: 190 PA-------SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGM 242
Query: 409 STLRYFTISSNELQSLP----CSLMQ 344
+L + N+L+ LP CSL++
Sbjct: 243 ESLELLYLRRNKLRFLPEFPSCSLLK 268
Score = 57.6 bits (133), Expect = 5e-08
Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 593
+L L LS +L + +I +K L LD ++N +E +PPE M +L L+L N+L
Sbjct: 198 SLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL-- 255
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIG 416
R+L LK L + N++ L K L ++ L DN + +P I
Sbjct: 256 ------RFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII 309
Query: 415 RISTLRYFTISSNELQSLPCSLMQCRLEYIDISSN 311
+ +L +S+N++ SLP SL L+++ + N
Sbjct: 310 LLRSLERLDLSNNDISSLPYSLGNLHLKFLALEGN 344
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 18/173 (10%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL- 599
R L+ LYL +L L +L LDLSNN + +P F +++L L+L++N+L
Sbjct: 151 RNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELK 210
Query: 598 ----GVRGVVDWRWL---------LGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 464
+ + + L + P++ ++L+LL L NKL LP+ L
Sbjct: 211 SLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKE 269
Query: 463 LKANDNMISRLPAT-IGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L +N I L A + ++++ + N+L+S+P ++ R LE +D+S+N
Sbjct: 270 LHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNN 322
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/118 (27%), Positives = 56/118 (47%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 512
L+LS + ++P R+ N+ AN L G + RW +TK + +++NK
Sbjct: 41 LNLSGRNLSEVPQCVWRI-NVDIPEEANQNLSF-GATE-RWWEQTDLTKLI----ISNNK 93
Query: 511 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR 338
L L + L L L +DN ++ LP+ I + L+ +S N+L+ LP + R
Sbjct: 94 LQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLR 151
Score = 42.3 bits (95), Expect = 0.002
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Frame = -2
Query: 553 ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNE 374
+ + L LDL +N L LP+ + L +L T+ + N LP + RI TL IS+N+
Sbjct: 470 VLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 529
Query: 373 LQSLPCSLMQC--RLEYIDISSN 311
+ S+ M+ L +D+ +N
Sbjct: 530 VGSVDPQKMKMMENLTTLDLQNN 552
Score = 37.5 bits (83), Expect = 0.054
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
TL+++ +S ++ + + + ++++L LDL NN++ ++PPE G NL L L N
Sbjct: 519 TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFR 578
Query: 595 V 593
V
Sbjct: 579 V 579
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/88 (29%), Positives = 43/88 (48%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L ++LS N + LP R+ L + ++NNQ+ G VD + + ++ + L L
Sbjct: 494 LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQV---GSVDPQKM---KMMENLTTL 547
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDN 446
DL +N L +P + L TL + N
Sbjct: 548 DLQNNDLLQIPPELGNCVNLRTLLLDGN 575
>AL138704-1|CAH73642.1| 734|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 1 protein.
Length = 734
Score = 64.9 bits (151), Expect = 3e-10
Identities = 48/149 (32%), Positives = 75/149 (50%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LS +L ++ L +L+L +N I +P + L+ L+L+ NQL
Sbjct: 104 LSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPAC-- 161
Query: 574 RWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
L G LK+L ++NKLG LP+ I +L++L+ L + N I+ LP IG++ +LR
Sbjct: 162 --LCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRE 215
Query: 394 FTISSNELQSLPCSLMQCRLEYIDISSNK 308
+ N L+ LP L+ L D S NK
Sbjct: 216 LNVRRNYLKVLPQELVDLSLVKFDFSCNK 244
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/85 (29%), Positives = 41/85 (48%)
Frame = -2
Query: 562 GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTIS 383
G ++ T++ DL+ N+L +P + L L N I +P I + L Y +S
Sbjct: 93 GHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLS 151
Query: 382 SNELQSLPCSLMQCRLEYIDISSNK 308
N+L +LP L L+ + S+NK
Sbjct: 152 RNQLSALPACLCGLPLKVLIASNNK 176
>AK222787-1|BAD96507.1| 671|Homo sapiens leucine rich repeat
containing 5 variant protein.
Length = 671
Score = 64.9 bits (151), Expect = 3e-10
Identities = 46/147 (31%), Positives = 72/147 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L L L K+ I +K+L L SNN++E LP + L L ++ N +
Sbjct: 496 KRLTCLKLWHNKIVTIPPSITHVKNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNIS 555
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + +G + + L+ L +T NK+ LPK ++K KL TL N I+ LP +G
Sbjct: 556 MIPIE-----IG--LLQDLQHLHITGNKVDILPKQLFKCIKLRTLNLGQNCITSLPEKVG 608
Query: 415 RISTLRYFTISSNELQSLPCSLMQCRL 335
++S L + N L LP L QCR+
Sbjct: 609 QLSQLTQLELKGNCLDRLPAQLGQCRM 635
Score = 64.5 bits (150), Expect = 4e-10
Identities = 45/156 (28%), Positives = 78/156 (50%), Gaps = 4/156 (2%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L+SLY S KL + + L+ L LD+S N I +P E G + +L LH+ N++
Sbjct: 519 KNLESLYFSNNKLESLPVAVFSLQKLRCLDVSYNNISMIPIEIGLLQDLQHLHITGNKVD 578
Query: 595 VRGVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
+ L Q+ K +KL L+L N + LP+ + +L +L L+ N + RLPA
Sbjct: 579 I---------LPKQLFKCIKLRTLNLGQNCITSLPEKVGQLSQLTQLELKGNCLDRLPAQ 629
Query: 421 IGRISTLRY--FTISSNELQSLPCSLMQCRLEYIDI 320
+G+ L+ + + +LP + + + I+I
Sbjct: 630 LGQCRMLKKSGLVVEDHLFDTLPLEVEEALNQDINI 665
>AK022951-1|BAB14326.1| 602|Homo sapiens protein ( Homo sapiens
cDNA FLJ12889 fis, clone NT2RP2004098, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 602
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/171 (29%), Positives = 86/171 (50%), Gaps = 17/171 (9%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV- 593
L L +S KL + D+ LL L VLD+ +N++ LP + NL +L++++N+L +
Sbjct: 84 LTKLIISNNKLQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKIL 143
Query: 592 -RGVVDWR-----WLLGPQIT---------KTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+ + R +L ++T L+ LDL++N L +P + L LV L
Sbjct: 144 PEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLN 203
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 308
+ N + LPA I R+ L++ +SN L+++P L LE + + NK
Sbjct: 204 LSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNK 254
Score = 58.0 bits (134), Expect = 4e-08
Identities = 43/146 (29%), Positives = 74/146 (50%), Gaps = 4/146 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
LQ L +S KL +I L++L L L +NE+ + F +++NL +L L+NN L
Sbjct: 130 LQKLNVSHNKLKILPEEITNLRNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTV 189
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+L L+L+SN+L LP I ++++L L N N++ +P + +
Sbjct: 190 PA-------SFSSLSSLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGM 242
Query: 409 STLRYFTISSNELQSLP----CSLMQ 344
+L + N+L+ LP CSL++
Sbjct: 243 ESLELLYLRRNKLRFLPEFPSCSLLK 268
Score = 57.6 bits (133), Expect = 5e-08
Identities = 45/155 (29%), Positives = 75/155 (48%), Gaps = 1/155 (0%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 593
+L L LS +L + +I +K L LD ++N +E +PPE M +L L+L N+L
Sbjct: 198 SLVRLNLSSNELKSLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL-- 255
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIG 416
R+L LK L + N++ L K L ++ L DN + +P I
Sbjct: 256 ------RFLPEFPSCSLLKELHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEII 309
Query: 415 RISTLRYFTISSNELQSLPCSLMQCRLEYIDISSN 311
+ +L +S+N++ SLP SL L+++ + N
Sbjct: 310 LLRSLERLDLSNNDISSLPYSLGNLHLKFLALEGN 344
Score = 50.4 bits (115), Expect = 7e-06
Identities = 48/173 (27%), Positives = 85/173 (49%), Gaps = 18/173 (10%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL- 599
R L+ LYL +L L +L LDLSNN + +P F +++L L+L++N+L
Sbjct: 151 RNLKCLYLQHNELTCISEGFEQLSNLEDLDLSNNHLTTVPASFSSLSSLVRLNLSSNELK 210
Query: 598 ----GVRGVVDWRWL---------LGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 464
+ + + L + P++ ++L+LL L NKL LP+ L
Sbjct: 211 SLPAEINRMKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKLRFLPE-FPSCSLLKE 269
Query: 463 LKANDNMISRLPAT-IGRISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L +N I L A + ++++ + N+L+S+P ++ R LE +D+S+N
Sbjct: 270 LHVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNN 322
Score = 42.3 bits (95), Expect = 0.002
Identities = 33/118 (27%), Positives = 56/118 (47%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNK 512
L+LS + ++P R+ N+ AN L G + RW +TK + +++NK
Sbjct: 41 LNLSGRNLSEVPQCVWRI-NVDIPEEANQNLSF-GATE-RWWEQTDLTKLI----ISNNK 93
Query: 511 LGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCR 338
L L + L L L +DN ++ LP+ I + L+ +S N+L+ LP + R
Sbjct: 94 LQSLTDDLRLLPALTVLDIHDNQLTSLPSAIRELENLQKLNVSHNKLKILPEEITNLR 151
Score = 42.3 bits (95), Expect = 0.002
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Frame = -2
Query: 553 ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNE 374
+ + L LDL +N L LP+ + L +L T+ + N LP + RI TL IS+N+
Sbjct: 470 VLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 529
Query: 373 LQSLPCSLMQC--RLEYIDISSN 311
+ S+ M+ L +D+ +N
Sbjct: 530 VGSVDPQKMKMMENLTTLDLQNN 552
Score = 37.5 bits (83), Expect = 0.054
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
TL+++ +S ++ + + + ++++L LDL NN++ ++PPE G NL L L N
Sbjct: 519 TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFR 578
Query: 595 V 593
V
Sbjct: 579 V 579
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/88 (29%), Positives = 43/88 (48%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L ++LS N + LP R+ L + ++NNQ+ G VD + + ++ + L L
Sbjct: 494 LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQV---GSVDPQKM---KMMENLTTL 547
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDN 446
DL +N L +P + L TL + N
Sbjct: 548 DLQNNDLLQIPPELGNCVNLRTLLLDGN 575
>AB208864-1|BAD92101.1| 1101|Homo sapiens flightless I homolog
variant protein.
Length = 1101
Score = 64.9 bits (151), Expect = 3e-10
Identities = 48/158 (30%), Positives = 86/158 (54%), Gaps = 5/158 (3%)
Frame = -2
Query: 769 LQSLYLSGLKLC--NFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
LQ+L+L + N + L +LA +DLS N++ ++P + +L L+L++NQ+
Sbjct: 187 LQTLHLRSTQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQIT 246
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMIS--RLPAT 422
+ +W+ ++ L+L+ N+L LP AI KL KL L N N + LP+
Sbjct: 247 ELSLCIDQWV-------HVETLNLSRNQLTSLPSAICKLSKLKKLYLNSNKLDFDGLPSG 299
Query: 421 IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
IG+++ L F ++N L+ +P SL +C +L + ++ N
Sbjct: 300 IGKLTNLEEFMAANNNLELVPESLCRCPKLRKLVLNKN 337
Score = 52.8 bits (121), Expect = 1e-06
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 1/135 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L LDLS N +E LPP+ R+ +L L L N L R L +TL L
Sbjct: 137 LTDLLYLDLSENRLESLPPQMRRLVHLQTLVLNGNPL---LHAQLRQLPAMTALQTLHLR 193
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
T +LP ++ L L + + N ++R+P + + +LR +SSN++ L +
Sbjct: 194 S-TQRTQSNLPTSLEGLSNLADVDLSCNDLTRVPECLYTLPSLRRLNLSSNQITELSLCI 252
Query: 349 MQ-CRLEYIDISSNK 308
Q +E +++S N+
Sbjct: 253 DQWVHVETLNLSRNQ 267
>BC117472-1|AAI17473.1| 763|Homo sapiens LRCH1 protein protein.
Length = 763
Score = 64.5 bits (150), Expect = 4e-10
Identities = 48/149 (32%), Positives = 75/149 (50%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LS +L ++ L +L+L +N I +P + L+ L+L+ NQL
Sbjct: 104 LSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPAC-- 161
Query: 574 RWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
L G LK+L ++NKLG LP+ I +L++L+ L + N I+ LP IG++ +LR
Sbjct: 162 --LCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRE 215
Query: 394 FTISSNELQSLPCSLMQCRLEYIDISSNK 308
+ N L+ LP L+ L D S NK
Sbjct: 216 LNVRRNYLKVLPQELVDLPLVKFDFSCNK 244
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/85 (29%), Positives = 41/85 (48%)
Frame = -2
Query: 562 GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTIS 383
G ++ T++ DL+ N+L +P + L L N I +P I + L Y +S
Sbjct: 93 GHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLS 151
Query: 382 SNELQSLPCSLMQCRLEYIDISSNK 308
N+L +LP L L+ + S+NK
Sbjct: 152 RNQLSALPACLCGLPLKVLIASNNK 176
>BC112937-1|AAI12938.1| 696|Homo sapiens LRCH1 protein protein.
Length = 696
Score = 64.5 bits (150), Expect = 4e-10
Identities = 48/149 (32%), Positives = 75/149 (50%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LS +L ++ L +L+L +N I +P + L+ L+L+ NQL
Sbjct: 104 LSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPAC-- 161
Query: 574 RWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
L G LK+L ++NKLG LP+ I +L++L+ L + N I+ LP IG++ +LR
Sbjct: 162 --LCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRE 215
Query: 394 FTISSNELQSLPCSLMQCRLEYIDISSNK 308
+ N L+ LP L+ L D S NK
Sbjct: 216 LNVRRNYLKVLPQELVDLPLVKFDFSCNK 244
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/85 (29%), Positives = 41/85 (48%)
Frame = -2
Query: 562 GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTIS 383
G ++ T++ DL+ N+L +P + L L N I +P I + L Y +S
Sbjct: 93 GHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLS 151
Query: 382 SNELQSLPCSLMQCRLEYIDISSNK 308
N+L +LP L L+ + S+NK
Sbjct: 152 RNQLSALPACLCGLPLKVLIASNNK 176
>AY050632-1|AAK95568.1| 728|Homo sapiens neuronal protein isoform B
protein.
Length = 728
Score = 64.5 bits (150), Expect = 4e-10
Identities = 48/149 (32%), Positives = 75/149 (50%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LS +L ++ L +L+L +N I +P + L+ L+L+ NQL
Sbjct: 104 LSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPAC-- 161
Query: 574 RWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
L G LK+L ++NKLG LP+ I +L++L+ L + N I+ LP IG++ +LR
Sbjct: 162 --LCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRE 215
Query: 394 FTISSNELQSLPCSLMQCRLEYIDISSNK 308
+ N L+ LP L+ L D S NK
Sbjct: 216 LNVRRNYLKVLPQELVDLPLVKFDFSCNK 244
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/85 (29%), Positives = 41/85 (48%)
Frame = -2
Query: 562 GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTIS 383
G ++ T++ DL+ N+L +P + L L N I +P I + L Y +S
Sbjct: 93 GHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLS 151
Query: 382 SNELQSLPCSLMQCRLEYIDISSNK 308
N+L +LP L L+ + S+NK
Sbjct: 152 RNQLSALPACLCGLPLKVLIASNNK 176
>AY050631-1|AAK95567.1| 696|Homo sapiens neuronal protein isoform a
protein.
Length = 696
Score = 64.5 bits (150), Expect = 4e-10
Identities = 48/149 (32%), Positives = 75/149 (50%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LS +L ++ L +L+L +N I +P + L+ L+L+ NQL
Sbjct: 104 LSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPAC-- 161
Query: 574 RWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
L G LK+L ++NKLG LP+ I +L++L+ L + N I+ LP IG++ +LR
Sbjct: 162 --LCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRE 215
Query: 394 FTISSNELQSLPCSLMQCRLEYIDISSNK 308
+ N L+ LP L+ L D S NK
Sbjct: 216 LNVRRNYLKVLPQELVDLPLVKFDFSCNK 244
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/85 (29%), Positives = 41/85 (48%)
Frame = -2
Query: 562 GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTIS 383
G ++ T++ DL+ N+L +P + L L N I +P I + L Y +S
Sbjct: 93 GHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLS 151
Query: 382 SNELQSLPCSLMQCRLEYIDISSNK 308
N+L +LP L L+ + S+NK
Sbjct: 152 RNQLSALPACLCGLPLKVLIASNNK 176
>AL022344-3|CAI23616.1| 146|Homo sapiens novel protein similar to
Ras suppressor protein 1r 4 (tax-transcriptionally act
protein.
Length = 146
Score = 64.5 bits (150), Expect = 4e-10
Identities = 47/141 (33%), Positives = 72/141 (51%), Gaps = 3/141 (2%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 542
+I LK+L VL+ NN+IEKLP + R+ L L+L N+L + G
Sbjct: 4 NIAELKNLEVLNFLNNQIEKLPTQISRLQKLKHLNLGMNRLNISP-------QGFGSLPA 56
Query: 541 LKLLDLTSNKL--GHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
L++LDLT N L +LP + L L L +DN LP IG+++ L+ + N L
Sbjct: 57 LEVLDLTYNNLNENYLPGNFFYLTTLCALYLSDNDFEILPPDIGKLTKLQILSNRDNNLI 116
Query: 367 SLPCSL-MQCRLEYIDISSNK 308
SLP + + +L+ + I N+
Sbjct: 117 SLPKEIRVLTQLKELHIQGNR 137
>AB023233-1|BAA76860.1| 793|Homo sapiens KIAA1016 protein protein.
Length = 793
Score = 64.5 bits (150), Expect = 4e-10
Identities = 48/149 (32%), Positives = 75/149 (50%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LS +L ++ L +L+L +N I +P + L+ L+L+ NQL
Sbjct: 169 LSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLSRNQLSALPAC-- 226
Query: 574 RWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
L G LK+L ++NKLG LP+ I +L++L+ L + N I+ LP IG++ +LR
Sbjct: 227 --LCG----LPLKVLIASNNKLGSLPEEIGQLKQLMELDVSCNEITALPQQIGQLKSLRE 280
Query: 394 FTISSNELQSLPCSLMQCRLEYIDISSNK 308
+ N L+ LP L+ L D S NK
Sbjct: 281 LNVRRNYLKVLPQELVDLPLVKFDFSCNK 309
Score = 41.9 bits (94), Expect = 0.002
Identities = 25/85 (29%), Positives = 41/85 (48%)
Frame = -2
Query: 562 GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTIS 383
G ++ T++ DL+ N+L +P + L L N I +P I + L Y +S
Sbjct: 158 GHDLSDTVQA-DLSKNRLVEVPMELCHFVSLEILNLYHNCIRVIPEAIVNLQMLTYLNLS 216
Query: 382 SNELQSLPCSLMQCRLEYIDISSNK 308
N+L +LP L L+ + S+NK
Sbjct: 217 RNQLSALPACLCGLPLKVLIASNNK 241
>AB020669-1|BAA74885.2| 584|Homo sapiens KIAA0862 protein protein.
Length = 584
Score = 63.7 bits (148), Expect = 7e-10
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 596
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 405 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 464
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 465 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 516
Query: 415 RISTLRYFTISSN-ELQSLPCSLMQC 341
+ L ++ N L SLP L C
Sbjct: 517 TLENLEELYLNDNPNLHSLPLELALC 542
Score = 59.3 bits (137), Expect = 2e-08
Identities = 49/170 (28%), Positives = 84/170 (49%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L +L LS L + + LK L +LDL +N++ ++P R+ +L+ L+L N++
Sbjct: 150 LMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTV 209
Query: 598 --GVRGVVDWRWL---------LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLK 458
++ + L L +I + L LD+ N+L HLPK I ++ L
Sbjct: 210 EKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLD 269
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
N + LP TIG +S+L + N L ++P SL +C LE +++ +N
Sbjct: 270 LQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENN 319
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 563
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 381 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 440
Query: 562 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 441 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 500
Query: 394 FTISSNELQSLP 359
+ N L LP
Sbjct: 501 LGLGENLLTHLP 512
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
LDL+ + LP +I +L +L L N + LPA +G + L +S N L SLP S
Sbjct: 107 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 166
Query: 352 LMQC-RLEYIDISSNK 308
L +L +D+ NK
Sbjct: 167 LDNLKKLRMLDLRHNK 182
>L12535-1|AAA60292.1| 277|Homo sapiens RSU-1 protein.
Length = 277
Score = 63.3 bits (147), Expect = 9e-10
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 416
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 308
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 545
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 371
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 370 QSLPCSLMQ-CRLEYIDISSN 311
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
>CR541840-1|CAG46639.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 63.3 bits (147), Expect = 9e-10
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 416
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 308
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 545
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 371
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 370 QSLPCSLMQ-CRLEYIDISSN 311
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
>CR536521-1|CAG38758.1| 277|Homo sapiens RSU1 protein.
Length = 277
Score = 63.3 bits (147), Expect = 9e-10
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 416
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 308
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 545
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 371
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 370 QSLPCSLMQ-CRLEYIDISSN 311
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
>BC107898-1|AAI07899.1| 280|Homo sapiens RSU1 protein protein.
Length = 280
Score = 63.3 bits (147), Expect = 9e-10
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 45 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 104
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 416
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 105 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 157
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 308
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 158 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 194
Score = 52.4 bits (120), Expect = 2e-06
Identities = 41/138 (29%), Positives = 66/138 (47%), Gaps = 5/138 (3%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--KTLK 536
L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ + LK
Sbjct: 42 LSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQKLK 92
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNELQSL 362
L+L N+L LP+ L L L N +S LP ++TLR +S N+ + L
Sbjct: 93 HLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEIL 152
Query: 361 PCSLMQ-CRLEYIDISSN 311
P + + +L+ + + N
Sbjct: 153 PPDIGKLTKLQILSLRDN 170
>BC106893-1|AAI06894.1| 250|Homo sapiens LRRC10 protein protein.
Length = 250
Score = 63.3 bits (147), Expect = 9e-10
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 4/153 (2%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LSG +L F + + L L LS+N + LPPE G++ NL L L N
Sbjct: 9 LSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKAL----- 63
Query: 574 RWLLGPQITKTLK---LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
PQ+ TLK +L L +NKL LP + L+ L TL N +++LP + +S
Sbjct: 64 -----PQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSL 118
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 308
L+ SN L+ LP L + + L I +S N+
Sbjct: 119 LKTLHAGSNALRLLPGQLRRLQELRTIWLSGNR 151
Score = 44.0 bits (99), Expect = 6e-04
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
K++DL+ ++L P + +LV L +DN ++ LP +G++ L+ + N ++LP
Sbjct: 5 KMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALP 64
Query: 358 ---CSLMQCRLEYI 326
C+L Q + Y+
Sbjct: 65 QVVCTLKQLCILYL 78
Score = 40.3 bits (90), Expect = 0.008
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = -2
Query: 760 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 581
LYL KLC+ ++ LL++L L + N + +LP ++ L LH +N L
Sbjct: 76 LYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNAL------ 129
Query: 580 DWRWLLGP-QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
R L G + + L+ + L+ N+L P + + L + + N I P ++ +S+
Sbjct: 130 --RLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFP-SLAHLSS 186
Query: 403 LRYFTISSNELQSLP 359
L+ N ++ P
Sbjct: 187 LKLVIYDHNPCRNAP 201
>BC106892-1|AAI06893.1| 249|Homo sapiens LRRC10 protein protein.
Length = 249
Score = 63.3 bits (147), Expect = 9e-10
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 4/153 (2%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LSG +L F + + L L LS+N + LPPE G++ NL L L N
Sbjct: 8 LSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKAL----- 62
Query: 574 RWLLGPQITKTLK---LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
PQ+ TLK +L L +NKL LP + L+ L TL N +++LP + +S
Sbjct: 63 -----PQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSL 117
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 308
L+ SN L+ LP L + + L I +S N+
Sbjct: 118 LKTLHAGSNALRLLPGQLRRLQELRTIWLSGNR 150
Score = 44.0 bits (99), Expect = 6e-04
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
K++DL+ ++L P + +LV L +DN ++ LP +G++ L+ + N ++LP
Sbjct: 4 KMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALP 63
Query: 358 ---CSLMQCRLEYI 326
C+L Q + Y+
Sbjct: 64 QVVCTLKQLCILYL 77
Score = 40.3 bits (90), Expect = 0.008
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = -2
Query: 760 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 581
LYL KLC+ ++ LL++L L + N + +LP ++ L LH +N L
Sbjct: 75 LYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNAL------ 128
Query: 580 DWRWLLGP-QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
R L G + + L+ + L+ N+L P + + L + + N I P ++ +S+
Sbjct: 129 --RLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFP-SLAHLSS 185
Query: 403 LRYFTISSNELQSLP 359
L+ N ++ P
Sbjct: 186 LKLVIYDHNPCRNAP 200
>BC090881-1|AAH90881.1| 277|Homo sapiens leucine rich repeat
containing 10 protein.
Length = 277
Score = 63.3 bits (147), Expect = 9e-10
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 4/153 (2%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LSG +L F + + L L LS+N + LPPE G++ NL L L N
Sbjct: 36 LSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKAL----- 90
Query: 574 RWLLGPQITKTLK---LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
PQ+ TLK +L L +NKL LP + L+ L TL N +++LP + +S
Sbjct: 91 -----PQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSL 145
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 308
L+ SN L+ LP L + + L I +S N+
Sbjct: 146 LKTLHAGSNALRLLPGQLRRLQELRTIWLSGNR 178
Score = 44.0 bits (99), Expect = 6e-04
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
K++DL+ ++L P + +LV L +DN ++ LP +G++ L+ + N ++LP
Sbjct: 32 KMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALP 91
Query: 358 ---CSLMQCRLEYI 326
C+L Q + Y+
Sbjct: 92 QVVCTLKQLCILYL 105
Score = 40.3 bits (90), Expect = 0.008
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = -2
Query: 760 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 581
LYL KLC+ ++ LL++L L + N + +LP ++ L LH +N L
Sbjct: 103 LYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNAL------ 156
Query: 580 DWRWLLGP-QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
R L G + + L+ + L+ N+L P + + L + + N I P ++ +S+
Sbjct: 157 --RLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFP-SLAHLSS 213
Query: 403 LRYFTISSNELQSLP 359
L+ N ++ P
Sbjct: 214 LKLVIYDHNPCRNAP 228
>BC050445-1|AAH50445.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 63.3 bits (147), Expect = 9e-10
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 596
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 403 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 463 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 415 RISTLRYFTISSN-ELQSLPCSLMQC 341
+ L ++ N L SLP L C
Sbjct: 515 TLENLEELYLNDNPNLHSLPFELALC 540
Score = 59.3 bits (137), Expect = 2e-08
Identities = 49/170 (28%), Positives = 84/170 (49%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L +L LS L + + LK L +LDL +N++ ++P R+ +L+ L+L N++
Sbjct: 148 LMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTV 207
Query: 598 --GVRGVVDWRWL---------LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLK 458
++ + L L +I + L LD+ N+L HLPK I ++ L
Sbjct: 208 EKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLD 267
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
N + LP TIG +S+L + N L ++P SL +C LE +++ +N
Sbjct: 268 LQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENN 317
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 563
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 562 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 498
Query: 394 FTISSNELQSLP 359
+ N L LP
Sbjct: 499 LGLGENLLTHLP 510
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
LDL+ + LP +I +L +L L N + LPA +G + L +S N L SLP S
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 352 LMQC-RLEYIDISSNK 308
L +L +D+ NK
Sbjct: 165 LDNLKKLRMLDLRHNK 180
>BC047306-1|AAH47306.1| 367|Homo sapiens leucine rich repeat
containing 28 protein.
Length = 367
Score = 63.3 bits (147), Expect = 9e-10
Identities = 49/156 (31%), Positives = 78/156 (50%), Gaps = 3/156 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L LYL + I L L LDLS+N +E + PE GR+ L L LANNQL
Sbjct: 67 LVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQL--- 123
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L P++ K L+ LD+++N+L LP+ + L L + N + +P +
Sbjct: 124 ------QFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLC 177
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++ +L +++ N L LP L + R L+Y+ + +N
Sbjct: 178 QLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNN 213
Score = 48.8 bits (111), Expect = 2e-05
Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L L SN + +P+AI L KL L +DN + + IGR+ LR+ +++N+LQ LP
Sbjct: 70 LYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPE 129
Query: 352 LMQCR-LEYIDISSNK 308
+ + L+ +DIS+N+
Sbjct: 130 VGDLKELQTLDISTNR 145
>BC015644-1|AAH15644.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 63.3 bits (147), Expect = 9e-10
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 416
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 308
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 545
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 371
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 370 QSLPCSLMQ-CRLEYIDISSN 311
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
>BC008691-1|AAH08691.1| 277|Homo sapiens RSU1 protein protein.
Length = 277
Score = 63.3 bits (147), Expect = 9e-10
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 416
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 308
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 545
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 371
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 370 QSLPCSLMQ-CRLEYIDISSN 311
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
>BC005993-1|AAH05993.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 63.3 bits (147), Expect = 9e-10
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 416
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 308
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 545
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 371
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 370 QSLPCSLMQ-CRLEYIDISSN 311
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
>AY358082-1|AAQ88449.1| 312|Homo sapiens ASEL436 protein.
Length = 312
Score = 63.3 bits (147), Expect = 9e-10
Identities = 49/156 (31%), Positives = 78/156 (50%), Gaps = 3/156 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L LYL + I L L LDLS+N +E + PE GR+ L L LANNQL
Sbjct: 67 LVELYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQL--- 123
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L P++ K L+ LD+++N+L LP+ + L L + N + +P +
Sbjct: 124 ------QFLPPEVGDLKELQTLDISTNRLLTLPERLHMCLSLQYLTVDRNRLWYVPRHLC 177
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
++ +L +++ N L LP L + R L+Y+ + +N
Sbjct: 178 QLPSLNELSMAGNRLAFLPLDLGRSRELQYVYVDNN 213
Score = 48.8 bits (111), Expect = 2e-05
Identities = 28/76 (36%), Positives = 46/76 (60%), Gaps = 1/76 (1%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L L SN + +P+AI L KL L +DN + + IGR+ LR+ +++N+LQ LP
Sbjct: 70 LYLHSNNIVVVPEAIGSLVKLQCLDLSDNALEIVCPEIGRLRALRHLRLANNQLQFLPPE 129
Query: 352 LMQCR-LEYIDISSNK 308
+ + L+ +DIS+N+
Sbjct: 130 VGDLKELQTLDISTNR 145
>AL365215-3|CAH73633.1| 277|Homo sapiens Ras suppressor protein 1
protein.
Length = 277
Score = 63.3 bits (147), Expect = 9e-10
Identities = 50/157 (31%), Positives = 77/157 (49%), Gaps = 3/157 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
+ L LS KL +I LK+L VL+ NN+IE+LP + + L L+L N+L
Sbjct: 42 ITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTL 101
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIG 416
G L++LDLT N L LP + L L L +DN LP IG
Sbjct: 102 P-------RGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIG 154
Query: 415 RISTLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 308
+++ L+ ++ N+L SLP + + +L+ + I N+
Sbjct: 155 KLTKLQILSLRDNDLISLPKEIGELTQLKELHIQGNR 191
Score = 52.8 bits (121), Expect = 1e-06
Identities = 41/141 (29%), Positives = 67/141 (47%), Gaps = 5/141 (3%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--K 545
+ L H+ L LS+N++ +PP + NL L+ NNQ+ L QI+ +
Sbjct: 36 LFTLSHITQLVLSHNKLTMVPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQ 86
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNEL 371
LK L+L N+L LP+ L L L N +S LP ++TLR +S N+
Sbjct: 87 KLKHLNLGMNRLNTLPRGFGSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDF 146
Query: 370 QSLPCSLMQ-CRLEYIDISSN 311
+ LP + + +L+ + + N
Sbjct: 147 EILPPDIGKLTKLQILSLRDN 167
>AL158163-3|CAH72813.1| 372|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 372
Score = 63.3 bits (147), Expect = 9e-10
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 596
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 193 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 252
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 253 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 304
Query: 415 RISTLRYFTISSN-ELQSLPCSLMQC 341
+ L ++ N L SLP L C
Sbjct: 305 TLENLEELYLNDNPNLHSLPFELALC 330
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 563
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 169 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 228
Query: 562 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 229 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 288
Query: 394 FTISSNELQSLP 359
+ N L LP
Sbjct: 289 LGLGENLLTHLP 300
Score = 48.0 bits (109), Expect = 4e-05
Identities = 22/66 (33%), Positives = 37/66 (56%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
K L++LDL NKL +P +++L+ L TL N I+ + I +S L +I N+++
Sbjct: 5 KKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIK 64
Query: 367 SLPCSL 350
LP +
Sbjct: 65 QLPAEI 70
Score = 46.8 bits (106), Expect = 9e-05
Identities = 45/167 (26%), Positives = 78/167 (46%), Gaps = 2/167 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 593
+L +LYL ++ +DI L L++L + N+I++LP E G +++LS L L N+L
Sbjct: 29 SLTTLYLRFNRITTVEKDIKNLSKLSMLSIRENKIKQLPAEIGNLSSLSRLGLRYNRLSA 88
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLP-ATI 419
R L L+ L+L +N + LP+++ L KL +L N P
Sbjct: 89 IP----RSLAK---CSALEELNLENNNISTLPESLLSSLVKLNSLTLARNCFQLYPVGGP 141
Query: 418 GRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDNKQNNSTS 278
+ ST+ + N + +P + R + + +K + K N TS
Sbjct: 142 SQFSTIYSLNMEHNRINKIPFGIFS-RAKVL----SKLNMKDNQLTS 183
>AL158163-2|CAH72812.1| 582|Homo sapiens soc-2 suppressor of clear
homolog (C. elegans) protein.
Length = 582
Score = 63.3 bits (147), Expect = 9e-10
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 596
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 403 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 463 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 415 RISTLRYFTISSN-ELQSLPCSLMQC 341
+ L ++ N L SLP L C
Sbjct: 515 TLENLEELYLNDNPNLHSLPFELALC 540
Score = 59.3 bits (137), Expect = 2e-08
Identities = 49/170 (28%), Positives = 84/170 (49%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L +L LS L + + LK L +LDL +N++ ++P R+ +L+ L+L N++
Sbjct: 148 LMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTV 207
Query: 598 --GVRGVVDWRWL---------LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLK 458
++ + L L +I + L LD+ N+L HLPK I ++ L
Sbjct: 208 EKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLD 267
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
N + LP TIG +S+L + N L ++P SL +C LE +++ +N
Sbjct: 268 LQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENN 317
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 563
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 562 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 498
Query: 394 FTISSNELQSLP 359
+ N L LP
Sbjct: 499 LGLGENLLTHLP 510
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
LDL+ + LP +I +L +L L N + LPA +G + L +S N L SLP S
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 352 LMQC-RLEYIDISSNK 308
L +L +D+ NK
Sbjct: 165 LDNLKKLRMLDLRHNK 180
>AK123908-1|BAC85724.1| 250|Homo sapiens protein ( Homo sapiens
cDNA FLJ41914 fis, clone PERIC2001228. ).
Length = 250
Score = 63.3 bits (147), Expect = 9e-10
Identities = 51/153 (33%), Positives = 74/153 (48%), Gaps = 4/153 (2%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW 575
LSG +L F + + L L LS+N + LPPE G++ NL L L N
Sbjct: 9 LSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKAL----- 63
Query: 574 RWLLGPQITKTLK---LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
PQ+ TLK +L L +NKL LP + L+ L TL N +++LP + +S
Sbjct: 64 -----PQVVCTLKQLCILYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSL 118
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSNK 308
L+ SN L+ LP L + + L I +S N+
Sbjct: 119 LKTLHAGSNALRLLPGQLRRLQELRTIWLSGNR 151
Score = 44.0 bits (99), Expect = 6e-04
Identities = 21/74 (28%), Positives = 41/74 (55%), Gaps = 3/74 (4%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
K++DL+ ++L P + +LV L +DN ++ LP +G++ L+ + N ++LP
Sbjct: 5 KMVDLSGSQLRRFPLHVCSFRELVKLYLSDNHLNSLPPELGQLQNLQILALDFNNFKALP 64
Query: 358 ---CSLMQCRLEYI 326
C+L Q + Y+
Sbjct: 65 QVVCTLKQLCILYL 78
Score = 40.3 bits (90), Expect = 0.008
Identities = 34/135 (25%), Positives = 62/135 (45%), Gaps = 1/135 (0%)
Frame = -2
Query: 760 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 581
LYL KLC+ ++ LL++L L + N + +LP ++ L LH +N L
Sbjct: 76 LYLGNNKLCDLPSELSLLQNLRTLWIEANCLTQLPDVVCELSLLKTLHAGSNAL------ 129
Query: 580 DWRWLLGP-QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
R L G + + L+ + L+ N+L P + + L + + N I P ++ +S+
Sbjct: 130 --RLLPGQLRRLQELRTIWLSGNRLTDFPTVLLHMPFLEVIDVDWNSIRYFP-SLAHLSS 186
Query: 403 LRYFTISSNELQSLP 359
L+ N ++ P
Sbjct: 187 LKLVIYDHNPCRNAP 201
>AF068920-1|AAC39856.1| 582|Homo sapiens Ras-binding protein SUR-8
protein.
Length = 582
Score = 63.3 bits (147), Expect = 9e-10
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 596
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 403 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 463 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 415 RISTLRYFTISSN-ELQSLPCSLMQC 341
+ L ++ N L SLP L C
Sbjct: 515 TLENLEELYLNDNPNLHSLPFELALC 540
Score = 59.3 bits (137), Expect = 2e-08
Identities = 49/170 (28%), Positives = 84/170 (49%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L +L LS L + + LK L +LDL +N++ ++P R+ +L+ L+L N++
Sbjct: 148 LMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTV 207
Query: 598 --GVRGVVDWRWL---------LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLK 458
++ + L L +I + L LD+ N+L HLPK I ++ L
Sbjct: 208 EKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLD 267
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
N + LP TIG +S+L + N L ++P SL +C LE +++ +N
Sbjct: 268 LQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENN 317
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 563
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 562 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 498
Query: 394 FTISSNELQSLP 359
+ N L LP
Sbjct: 499 LGLGENLLTHLP 510
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
LDL+ + LP +I +L +L L N + LPA +G + L +S N L SLP S
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 352 LMQC-RLEYIDISSNK 308
L +L +D+ NK
Sbjct: 165 LDNLKKLRMLDLRHNK 180
>AF054828-1|AAC25698.1| 582|Homo sapiens leucine-rich repeat
protein SHOC-2 protein.
Length = 582
Score = 63.3 bits (147), Expect = 9e-10
Identities = 48/146 (32%), Positives = 71/146 (48%), Gaps = 2/146 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-G 596
++ L L+ +L D+ L L VL LSNN ++KLP G + L EL L N+L
Sbjct: 403 SMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLKKLPHGLGNLRKLRELDLEENKLES 462
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L+ L LT+N+L LP+ I L L L +N+++ LP IG
Sbjct: 463 LPNEIAY--------LKDLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIG 514
Query: 415 RISTLRYFTISSN-ELQSLPCSLMQC 341
+ L ++ N L SLP L C
Sbjct: 515 TLENLEELYLNDNPNLHSLPFELALC 540
Score = 59.3 bits (137), Expect = 2e-08
Identities = 49/170 (28%), Positives = 84/170 (49%), Gaps = 17/170 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL--- 599
L +L LS L + + LK L +LDL +N++ ++P R+ +L+ L+L N++
Sbjct: 148 LMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITTV 207
Query: 598 --GVRGVVDWRWL---------LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLK 458
++ + L L +I + L LD+ N+L HLPK I ++ L
Sbjct: 208 EKDIKNLSKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLD 267
Query: 457 ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
N + LP TIG +S+L + N L ++P SL +C LE +++ +N
Sbjct: 268 LQHNELLDLPDTIGNLSSLSRLGLRYNRLSAIPRSLAKCSALEELNLENN 317
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/132 (32%), Positives = 65/132 (49%), Gaps = 16/132 (12%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-----GVRGVVDWRWLL------- 563
K L+ L++ +N++ LP +FG ++ EL+LA NQL V G+V L+
Sbjct: 379 KVLSKLNMKDNQLTSLPLDFGTWTSMVELNLATNQLTKIPEDVSGLVSLEVLILSNNLLK 438
Query: 562 ----GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
G + L+ LDL NKL LP I L+ L L +N ++ LP IG ++ L +
Sbjct: 439 KLPHGLGNLRKLRELDLEENKLESLPNEIAYLKDLQKLVLTNNQLTTLPRGIGHLTNLTH 498
Query: 394 FTISSNELQSLP 359
+ N L LP
Sbjct: 499 LGLGENLLTHLP 510
Score = 45.6 bits (103), Expect = 2e-04
Identities = 27/76 (35%), Positives = 39/76 (51%), Gaps = 1/76 (1%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
LDL+ + LP +I +L +L L N + LPA +G + L +S N L SLP S
Sbjct: 105 LDLSKRSIHILPSSIKELTQLTELYLYSNKLQSLPAEVGCLVNLMTLALSENSLTSLPDS 164
Query: 352 LMQC-RLEYIDISSNK 308
L +L +D+ NK
Sbjct: 165 LDNLKKLRMLDLRHNK 180
>AL391728-3|CAH73693.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/139 (28%), Positives = 67/139 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 140
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 141 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 196
Query: 415 RISTLRYFTISSNELQSLP 359
R+ LR + N L++LP
Sbjct: 197 RLVKLRILELRENHLKTLP 215
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
+TL+ L L +N++ LPK ++ + L L DN +S LP TI + L+ IS N +Q
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQ 143
Query: 367 SLPCSLMQCR-LEYIDISSN 311
P ++ C+ L I+ S N
Sbjct: 144 EFPENIKCCKCLTIIEASVN 163
Score = 35.5 bits (78), Expect = 0.22
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 1/138 (0%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 521
L L L N+IE+LP + L +L + +N L + + + LK LD++
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLS-----NLPTTIASLVN--LKELDIS 138
Query: 520 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ- 344
N + P+ I + L ++A+ N IS+LP ++ L ++ L+ LP + +
Sbjct: 139 KNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRL 198
Query: 343 CRLEYIDISSNKFDNKQN 290
+L +++ N N
Sbjct: 199 VKLRILELRENHLKTLPN 216
>AL359894-1|CAH73131.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/139 (28%), Positives = 67/139 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 140
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 141 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 196
Query: 415 RISTLRYFTISSNELQSLP 359
R+ LR + N L++LP
Sbjct: 197 RLVKLRILELRENHLKTLP 215
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
+TL+ L L +N++ LPK ++ + L L DN +S LP TI + L+ IS N +Q
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQ 143
Query: 367 SLPCSLMQCR-LEYIDISSN 311
P ++ C+ L I+ S N
Sbjct: 144 EFPENIKCCKCLTIIEASVN 163
Score = 35.5 bits (78), Expect = 0.22
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 1/138 (0%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 521
L L L N+IE+LP + L +L + +N L + + + LK LD++
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLS-----NLPTTIASLVN--LKELDIS 138
Query: 520 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ- 344
N + P+ I + L ++A+ N IS+LP ++ L ++ L+ LP + +
Sbjct: 139 KNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRL 198
Query: 343 CRLEYIDISSNKFDNKQN 290
+L +++ N N
Sbjct: 199 VKLRILELRENHLKTLPN 216
>AL359412-3|CAH74020.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/139 (28%), Positives = 67/139 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 140
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 141 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 196
Query: 415 RISTLRYFTISSNELQSLP 359
R+ LR + N L++LP
Sbjct: 197 RLVKLRILELRENHLKTLP 215
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
+TL+ L L +N++ LPK ++ + L L DN +S LP TI + L+ IS N +Q
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQ 143
Query: 367 SLPCSLMQCR-LEYIDISSN 311
P ++ C+ L I+ S N
Sbjct: 144 EFPENIKCCKCLTIIEASVN 163
Score = 35.5 bits (78), Expect = 0.22
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 1/138 (0%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 521
L L L N+IE+LP + L +L + +N L + + + LK LD++
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLS-----NLPTTIASLVN--LKELDIS 138
Query: 520 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ- 344
N + P+ I + L ++A+ N IS+LP ++ L ++ L+ LP + +
Sbjct: 139 KNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRL 198
Query: 343 CRLEYIDISSNKFDNKQN 290
+L +++ N N
Sbjct: 199 VKLRILELRENHLKTLPN 216
>AL117353-2|CAI23424.1| 217|Homo sapiens leucine rich repeat
containing 7 protein.
Length = 217
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/139 (28%), Positives = 67/139 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 140
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 141 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 196
Query: 415 RISTLRYFTISSNELQSLP 359
R+ LR + N L++LP
Sbjct: 197 RLVKLRILELRENHLKTLP 215
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
+TL+ L L +N++ LPK ++ + L L DN +S LP TI + L+ IS N +Q
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQ 143
Query: 367 SLPCSLMQCR-LEYIDISSN 311
P ++ C+ L I+ S N
Sbjct: 144 EFPENIKCCKCLTIIEASVN 163
Score = 35.5 bits (78), Expect = 0.22
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 1/138 (0%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 521
L L L N+IE+LP + L +L + +N L + + + LK LD++
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLS-----NLPTTIASLVN--LKELDIS 138
Query: 520 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ- 344
N + P+ I + L ++A+ N IS+LP ++ L ++ L+ LP + +
Sbjct: 139 KNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRL 198
Query: 343 CRLEYIDISSNKFDNKQN 290
+L +++ N N
Sbjct: 199 VKLRILELRENHLKTLPN 216
>AF498274-1|AAP06801.1| 217|Homo sapiens densin-180 like protein
protein.
Length = 217
Score = 62.9 bits (146), Expect = 1e-09
Identities = 39/139 (28%), Positives = 67/139 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
RTL+ LYL ++ + + + L L + +N++ LP + NL EL ++ N
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKN--- 140
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
GV ++ + + K L +++ + N + LP +L L L ND + LPA G
Sbjct: 141 --GVQEFPENI--KCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFG 196
Query: 415 RISTLRYFTISSNELQSLP 359
R+ LR + N L++LP
Sbjct: 197 RLVKLRILELRENHLKTLP 215
Score = 49.2 bits (112), Expect = 2e-05
Identities = 28/80 (35%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
+TL+ L L +N++ LPK ++ + L L DN +S LP TI + L+ IS N +Q
Sbjct: 84 RTLEELYLDANQIEELPKQLFNCQALRKLSIPDNDLSNLPTTIASLVNLKELDISKNGVQ 143
Query: 367 SLPCSLMQCR-LEYIDISSN 311
P ++ C+ L I+ S N
Sbjct: 144 EFPENIKCCKCLTIIEASVN 163
Score = 35.5 bits (78), Expect = 0.22
Identities = 33/138 (23%), Positives = 62/138 (44%), Gaps = 1/138 (0%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 521
L L L N+IE+LP + L +L + +N L + + + LK LD++
Sbjct: 86 LEELYLDANQIEELPKQLFNCQALRKLSIPDNDLS-----NLPTTIASLVN--LKELDIS 138
Query: 520 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ- 344
N + P+ I + L ++A+ N IS+LP ++ L ++ L+ LP + +
Sbjct: 139 KNGVQEFPENIKCCKCLTIIEASVNPISKLPDGFTQLLNLTQLYLNDAFLEFLPANFGRL 198
Query: 343 CRLEYIDISSNKFDNKQN 290
+L +++ N N
Sbjct: 199 VKLRILELRENHLKTLPN 216
>BC126277-1|AAI26278.1| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 2/136 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR-GVVDWRWLLGPQITKTLKLL 530
+ ++ +DLS +E LP +L+ L+L N L + R L Q LK L
Sbjct: 125 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSL 184
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+L++N LG P A+ + L L + N + +PA +G + L+ F + N LQSLP L
Sbjct: 185 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 244
Query: 349 MQCR-LEYIDISSNKF 305
+ L Y+ +S N+F
Sbjct: 245 ENMKQLSYLGLSFNEF 260
Score = 46.8 bits (106), Expect = 9e-05
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW--RWLLGPQ-- 554
++ L+H+ LDL +N++ L N+ LH NQL + + + L
Sbjct: 314 EVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDICGYFLKALYASSNE 371
Query: 553 --------ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
+ L +D++ N+L ++P+ + + KL L N I LPA + S+LR
Sbjct: 372 LVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLR 431
Query: 397 YFTISSNELQSLPCSLMQCRLEYIDISSNK 308
N+L LP L + +E +D+ N+
Sbjct: 432 KLLAGHNQLARLPERLERTSVEVLDVQHNQ 461
Score = 44.0 bits (99), Expect = 6e-04
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Frame = -2
Query: 715 LLLK--HLAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQI 551
LL+K L L+ S N++E LPP N L EL+L NN L + V P +
Sbjct: 469 LLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCV--------PLL 520
Query: 550 T--KTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 380
T LK+L + N+L P + + KLE+L + + N + +P TI + S
Sbjct: 521 TGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHS 580
Query: 379 NELQSLPCSLMQCRLEYIDISSNK 308
N ++ P + ++ +D+S N+
Sbjct: 581 NCIEVFPEVMQLPEIKCVDLSCNE 604
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Frame = -2
Query: 550 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
++ L++LD+ N++ LP ++ L L A N ++RLP + R S + + N+L
Sbjct: 404 SRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQL 462
Query: 370 QSLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 272
LP +L+ L +++ S+NK ++ + S++
Sbjct: 463 LELPPNLLMKADSLRFLNASANKLESLPPATLSEE 497
Score = 36.3 bits (80), Expect = 0.12
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 22/179 (12%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
P L + +S +L N + + L VLD+ +N+I +LP ++L +L +NQL
Sbjct: 381 PNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQL 440
Query: 598 G------------VRGVVDWRWL-LGPQI---TKTLKLLDLTSNKLGHLPKAIWKLEKLV 467
V V + L L P + +L+ L+ ++NKL LP A E
Sbjct: 441 ARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNS 500
Query: 466 TLK----ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNK 308
L+ N+++ + + L+ ++ N LQS P S M LE ID+S NK
Sbjct: 501 ILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNK 559
Score = 33.1 bits (72), Expect = 1.2
Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 18/175 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN---QL 599
LQ+ L G L + ++ +K L+ L LS NE +P ++ + +L ++ N L
Sbjct: 227 LQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETL 286
Query: 598 GVRGV--------VDWRW-----LLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 464
++ + VD R L+ ++ + + LDL NKLG L I+ +
Sbjct: 287 RLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFN--NIEV 344
Query: 463 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDN 299
L N + L G L+ SSNEL L + L Y+D+S N+ +N
Sbjct: 345 LHCERNQLVTLDIC-GYF--LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLEN 396
>BC014927-1|AAH14927.3| 1205|Homo sapiens PH domain and leucine rich
repeat protein phosphatase protein.
Length = 1205
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 2/136 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR-GVVDWRWLLGPQITKTLKLL 530
+ ++ +DLS +E LP +L+ L+L N L + R L Q LK L
Sbjct: 125 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSL 184
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+L++N LG P A+ + L L + N + +PA +G + L+ F + N LQSLP L
Sbjct: 185 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 244
Query: 349 MQCR-LEYIDISSNKF 305
+ L Y+ +S N+F
Sbjct: 245 ENMKQLSYLGLSFNEF 260
Score = 46.8 bits (106), Expect = 9e-05
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW--RWLLGPQ-- 554
++ L+H+ LDL +N++ L N+ LH NQL + + + L
Sbjct: 314 EVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDICGYFLKALYASSNE 371
Query: 553 --------ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
+ L +D++ N+L ++P+ + + KL L N I LPA + S+LR
Sbjct: 372 LVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLR 431
Query: 397 YFTISSNELQSLPCSLMQCRLEYIDISSNK 308
N+L LP L + +E +D+ N+
Sbjct: 432 KLLAGHNQLARLPERLERTSVEVLDVQHNQ 461
Score = 44.0 bits (99), Expect = 6e-04
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Frame = -2
Query: 715 LLLK--HLAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQI 551
LL+K L L+ S N++E LPP N L EL+L NN L + V P +
Sbjct: 469 LLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCV--------PLL 520
Query: 550 T--KTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 380
T LK+L + N+L P + + KLE+L + + N + +P TI + S
Sbjct: 521 TGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHS 580
Query: 379 NELQSLPCSLMQCRLEYIDISSNK 308
N ++ P + ++ +D+S N+
Sbjct: 581 NCIEVFPEVMQLPEIKCVDLSCNE 604
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Frame = -2
Query: 550 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
++ L++LD+ N++ LP ++ L L A N ++RLP + R S + + N+L
Sbjct: 404 SRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQL 462
Query: 370 QSLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 272
LP +L+ L +++ S+NK ++ + S++
Sbjct: 463 LELPPNLLMKADSLRFLNASANKLESLPPATLSEE 497
Score = 36.3 bits (80), Expect = 0.12
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 22/179 (12%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
P L + +S +L N + + L VLD+ +N+I +LP ++L +L +NQL
Sbjct: 381 PNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQL 440
Query: 598 G------------VRGVVDWRWL-LGPQI---TKTLKLLDLTSNKLGHLPKAIWKLEKLV 467
V V + L L P + +L+ L+ ++NKL LP A E
Sbjct: 441 ARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNS 500
Query: 466 TLK----ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNK 308
L+ N+++ + + L+ ++ N LQS P S M LE ID+S NK
Sbjct: 501 ILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNK 559
Score = 33.1 bits (72), Expect = 1.2
Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 18/175 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN---QL 599
LQ+ L G L + ++ +K L+ L LS NE +P ++ + +L ++ N L
Sbjct: 227 LQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETL 286
Query: 598 GVRGV--------VDWRW-----LLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 464
++ + VD R L+ ++ + + LDL NKLG L I+ +
Sbjct: 287 RLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFN--NIEV 344
Query: 463 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDN 299
L N + L G L+ SSNEL L + L Y+D+S N+ +N
Sbjct: 345 LHCERNQLVTLDIC-GYF--LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLEN 396
>AK001924-1|BAA91980.1| 721|Homo sapiens protein ( Homo sapiens
cDNA FLJ11062 fis, clone PLACE1004804, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 721
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 2/136 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR-GVVDWRWLLGPQITKTLKLL 530
+ ++ +DLS +E LP +L+ L+L N L + R L Q LK L
Sbjct: 125 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFAKLKSL 184
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+L++N LG P A+ + L L + N + +PA +G + L+ F + N LQSLP L
Sbjct: 185 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 244
Query: 349 MQCR-LEYIDISSNKF 305
+ L Y+ +S N+F
Sbjct: 245 ENMKQLSYLGLSFNEF 260
Score = 46.8 bits (106), Expect = 9e-05
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW--RWLLGPQ-- 554
++ L+H+ LDL +N++ L N+ LH NQL + + + L
Sbjct: 314 EVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDICGYFLKALYASSNE 371
Query: 553 --------ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
+ L +D++ N+L ++P+ + + KL L N I LPA + S+LR
Sbjct: 372 LVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLR 431
Query: 397 YFTISSNELQSLPCSLMQCRLEYIDISSNK 308
N+L LP L + +E +D+ N+
Sbjct: 432 KLLAGHNQLARLPERLERTSVEVLDVQHNQ 461
Score = 44.0 bits (99), Expect = 6e-04
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Frame = -2
Query: 715 LLLK--HLAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQI 551
LL+K L L+ S N++E LPP N L EL+L NN L + V P +
Sbjct: 469 LLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCV--------PLL 520
Query: 550 T--KTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 380
T LK+L + N+L P + + KLE+L + + N + +P TI + S
Sbjct: 521 TGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHS 580
Query: 379 NELQSLPCSLMQCRLEYIDISSNK 308
N ++ P + ++ +D+S N+
Sbjct: 581 NCIEVFPEVMQLPEIKCVDLSCNE 604
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Frame = -2
Query: 550 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
++ L++LD+ N++ LP ++ L L A N ++RLP + R S + + N+L
Sbjct: 404 SRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQL 462
Query: 370 QSLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 272
LP +L+ L +++ S+NK ++ + S++
Sbjct: 463 LELPPNLLMKADSLRFLNASANKLESLPPATLSEE 497
Score = 36.3 bits (80), Expect = 0.12
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 22/179 (12%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
P L + +S +L N + + L VLD+ +N+I +LP ++L +L +NQL
Sbjct: 381 PNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQL 440
Query: 598 G------------VRGVVDWRWL-LGPQI---TKTLKLLDLTSNKLGHLPKAIWKLEKLV 467
V V + L L P + +L+ L+ ++NKL LP A E
Sbjct: 441 ARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNS 500
Query: 466 TLK----ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNK 308
L+ N+++ + + L+ ++ N LQS P S M LE ID+S NK
Sbjct: 501 ILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNK 559
Score = 33.1 bits (72), Expect = 1.2
Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 18/175 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN---QL 599
LQ+ L G L + ++ +K L+ L LS NE +P ++ + +L ++ N L
Sbjct: 227 LQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETL 286
Query: 598 GVRGV--------VDWRW-----LLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 464
++ + VD R L+ ++ + + LDL NKLG L I+ +
Sbjct: 287 RLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFN--NIEV 344
Query: 463 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDN 299
L N + L G L+ SSNEL L + L Y+D+S N+ +N
Sbjct: 345 LHCERNQLVTLDIC-GYF--LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLEN 396
>AB011178-1|BAA25532.2| 1369|Homo sapiens KIAA0606 protein protein.
Length = 1369
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/136 (31%), Positives = 68/136 (50%), Gaps = 2/136 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR-GVVDWRWLLGPQITKTLKLL 530
+ ++ +DLS +E LP +L+ L+L N L + R L Q LK L
Sbjct: 289 QRISSVDLSCCSLEHLPANLFYSQDLTHLNLKQNFLRQNPSLPAARGLNELQRFTKLKSL 348
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+L++N LG P A+ + L L + N + +PA +G + L+ F + N LQSLP L
Sbjct: 349 NLSNNHLGDFPLAVCSIPTLAELNVSCNALRSVPAAVGVMHNLQTFLLDGNFLQSLPAEL 408
Query: 349 MQCR-LEYIDISSNKF 305
+ L Y+ +S N+F
Sbjct: 409 ENMKQLSYLGLSFNEF 424
Score = 46.8 bits (106), Expect = 9e-05
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW--RWLLGPQ-- 554
++ L+H+ LDL +N++ L N+ LH NQL + + + L
Sbjct: 478 EVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDICGYFLKALYASSNE 535
Query: 553 --------ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
+ L +D++ N+L ++P+ + + KL L N I LPA + S+LR
Sbjct: 536 LVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLR 595
Query: 397 YFTISSNELQSLPCSLMQCRLEYIDISSNK 308
N+L LP L + +E +D+ N+
Sbjct: 596 KLLAGHNQLARLPERLERTSVEVLDVQHNQ 625
Score = 46.0 bits (104), Expect = 2e-04
Identities = 43/144 (29%), Positives = 69/144 (47%), Gaps = 8/144 (5%)
Frame = -2
Query: 715 LLLK--HLAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQI 551
LL+K L L+ S N++E LPP N L EL+L NN L + V P +
Sbjct: 633 LLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCV--------PLL 684
Query: 550 T--KTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 380
T LK+L + N+L P + + KLE+L + + N + +P TI S + S
Sbjct: 685 TGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCSRMHTVIAHS 744
Query: 379 NELQSLPCSLMQCRLEYIDISSNK 308
N ++ P + ++ +D+S N+
Sbjct: 745 NCIEVFPEVMQLPEIKCVDLSCNE 768
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Frame = -2
Query: 550 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
++ L++LD+ N++ LP ++ L L A N ++RLP + R S + + N+L
Sbjct: 568 SRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQL 626
Query: 370 QSLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 272
LP +L+ L +++ S+NK ++ + S++
Sbjct: 627 LELPPNLLMKADSLRFLNASANKLESLPPATLSEE 661
Score = 36.3 bits (80), Expect = 0.12
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 22/179 (12%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
P L + +S +L N + + L VLD+ +N+I +LP ++L +L +NQL
Sbjct: 545 PNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQL 604
Query: 598 G------------VRGVVDWRWL-LGPQI---TKTLKLLDLTSNKLGHLPKAIWKLEKLV 467
V V + L L P + +L+ L+ ++NKL LP A E
Sbjct: 605 ARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNS 664
Query: 466 TLK----ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNK 308
L+ N+++ + + L+ ++ N LQS P S M LE ID+S NK
Sbjct: 665 ILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNK 723
Score = 33.1 bits (72), Expect = 1.2
Identities = 46/175 (26%), Positives = 76/175 (43%), Gaps = 18/175 (10%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN---QL 599
LQ+ L G L + ++ +K L+ L LS NE +P ++ + +L ++ N L
Sbjct: 391 LQTFLLDGNFLQSLPAELENMKQLSYLGLSFNEFTDIPEVLEKLTAVDKLCMSGNCVETL 450
Query: 598 GVRGV--------VDWRW-----LLGPQIT--KTLKLLDLTSNKLGHLPKAIWKLEKLVT 464
++ + VD R L+ ++ + + LDL NKLG L I+ +
Sbjct: 451 RLQALRKMPHIKHVDLRLNVIRKLIADEVDFLQHVTQLDLRDNKLGDLDAMIFN--NIEV 508
Query: 463 LKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNKFDN 299
L N + L G L+ SSNEL L + L Y+D+S N+ +N
Sbjct: 509 LHCERNQLVTLDIC-GYF--LKALYASSNELVQLDVYPVPNYLSYMDVSRNRLEN 560
>BC013757-1|AAH13757.1| 403|Homo sapiens LRRC58 protein protein.
Length = 403
Score = 60.5 bits (140), Expect = 7e-09
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 1/136 (0%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 524
HL +LD+S N + L PE + L L NN+LG + + L + ++L++L+L
Sbjct: 101 HLQLLDVSGNALTALGPELLALRGLRTLLAKNNRLGGPSALP-KGLAQSPLCRSLQVLNL 159
Query: 523 TSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ 344
+ N +P ++ +L L TL N + +PA I + +L + N ++ +P L
Sbjct: 160 SGNCFQEVPASLLELRALQTLSLGGNQLQSIPAEIENLQSLECLYLGGNFIKEIPPELGN 219
Query: 343 C-RLEYIDISSNKFDN 299
L Y+ + NK +
Sbjct: 220 LPSLNYLVLCDNKIQS 235
Score = 35.1 bits (77), Expect = 0.29
Identities = 19/59 (32%), Positives = 33/59 (55%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
++L+ LYL G + ++ L L L L +N+I+ +PP+ ++ +L L L NN L
Sbjct: 198 QSLECLYLGGNFIKEIPPELGNLPSLNYLVLCDNKIQSIPPQLSQLHSLRSLSLHNNLL 256
>AL365215-2|CAH73632.1| 224|Homo sapiens Ras suppressor protein 1
protein.
Length = 224
Score = 60.1 bits (139), Expect = 9e-09
Identities = 45/141 (31%), Positives = 71/141 (50%), Gaps = 3/141 (2%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT 542
+I LK+L VL+ NN+IE+LP + + L L+L N+L G
Sbjct: 5 NIAELKNLEVLNFFNNQIEELPTQISSLQKLKHLNLGMNRLNTLP-------RGFGSLPA 57
Query: 541 LKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
L++LDLT N L LP + L L L +DN LP IG+++ L+ ++ N+L
Sbjct: 58 LEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLRDNDLI 117
Query: 367 SLPCSLMQ-CRLEYIDISSNK 308
SLP + + +L+ + I N+
Sbjct: 118 SLPKEIGELTQLKELHIQGNR 138
Score = 40.7 bits (91), Expect = 0.006
Identities = 35/122 (28%), Positives = 56/122 (45%), Gaps = 5/122 (4%)
Frame = -2
Query: 661 LPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--KTLKLLDLTSNKLGHLPKAI 488
+PP + NL L+ NNQ+ L QI+ + LK L+L N+L LP+
Sbjct: 2 VPPNIAELKNLEVLNFFNNQIEE---------LPTQISSLQKLKHLNLGMNRLNTLPRGF 52
Query: 487 WKLEKLVTLKANDNMISR--LPATIGRISTLRYFTISSNELQSLPCSLMQ-CRLEYIDIS 317
L L L N +S LP ++TLR +S N+ + LP + + +L+ + +
Sbjct: 53 GSLPALEVLDLTYNNLSENSLPGNFFYLTTLRALYLSDNDFEILPPDIGKLTKLQILSLR 112
Query: 316 SN 311
N
Sbjct: 113 DN 114
>BC009613-1|AAH09613.1| 335|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 335
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/155 (30%), Positives = 73/155 (47%), Gaps = 2/155 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLS-NNEIEKLPPEFGRMANLSELHLANNQLGV 593
LQ L LS K+ +++ L L+L+ N +I LP E + L+ L L+ N
Sbjct: 131 LQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTT 190
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+ L P L+ LD+ SNKL LP I +++ L TL N I+ LP TI
Sbjct: 191 ---IPLAVLNMP----ALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTISN 243
Query: 412 ISTLRYFTISSNELQSLP-CSLMQCRLEYIDISSN 311
+ L +S+N+LQ +P C L +++ N
Sbjct: 244 MKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
Score = 52.8 bits (121), Expect = 1e-06
Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 18/154 (11%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV--RGVVDWRWL----------- 566
++L VLDLS N I ++PP G + L EL L+ N++ + + + L
Sbjct: 106 QNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDI 165
Query: 565 --LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L +++ LKL LDL+ N +P A+ + L L N + +LP TI R+ L
Sbjct: 166 CDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLH 225
Query: 397 YFTISSNELQSLPCSLMQCR-LEYIDISSNKFDN 299
+ NE+ LP ++ + L + +S+NK +
Sbjct: 226 TLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQD 259
Score = 33.1 bits (72), Expect = 1.2
Identities = 18/62 (29%), Positives = 35/62 (56%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L +L+L ++ + I +K+L L LSNN+++ +P MANL ++ +N L
Sbjct: 222 QNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Query: 595 VR 590
++
Sbjct: 282 LK 283
>AY358131-1|AAQ88498.1| 335|Homo sapiens densin hlg protein.
Length = 335
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/155 (30%), Positives = 73/155 (47%), Gaps = 2/155 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLS-NNEIEKLPPEFGRMANLSELHLANNQLGV 593
LQ L LS K+ +++ L L+L+ N +I LP E + L+ L L+ N
Sbjct: 131 LQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTT 190
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+ L P L+ LD+ SNKL LP I +++ L TL N I+ LP TI
Sbjct: 191 ---IPLAVLNMP----ALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTISN 243
Query: 412 ISTLRYFTISSNELQSLP-CSLMQCRLEYIDISSN 311
+ L +S+N+LQ +P C L +++ N
Sbjct: 244 MKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
Score = 52.8 bits (121), Expect = 1e-06
Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 18/154 (11%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV--RGVVDWRWL----------- 566
++L VLDLS N I ++PP G + L EL L+ N++ + + + L
Sbjct: 106 QNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDI 165
Query: 565 --LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L +++ LKL LDL+ N +P A+ + L L N + +LP TI R+ L
Sbjct: 166 CDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLH 225
Query: 397 YFTISSNELQSLPCSLMQCR-LEYIDISSNKFDN 299
+ NE+ LP ++ + L + +S+NK +
Sbjct: 226 TLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQD 259
Score = 33.1 bits (72), Expect = 1.2
Identities = 18/62 (29%), Positives = 35/62 (56%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L +L+L ++ + I +K+L L LSNN+++ +P MANL ++ +N L
Sbjct: 222 QNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Query: 595 VR 590
++
Sbjct: 282 LK 283
>AL445928-6|CAH72254.1| 339|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 339
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/155 (30%), Positives = 73/155 (47%), Gaps = 2/155 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLS-NNEIEKLPPEFGRMANLSELHLANNQLGV 593
LQ L LS K+ +++ L L+L+ N +I LP E + L+ L L+ N
Sbjct: 131 LQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTT 190
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+ L P L+ LD+ SNKL LP I +++ L TL N I+ LP TI
Sbjct: 191 ---IPLAVLNMP----ALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTISN 243
Query: 412 ISTLRYFTISSNELQSLP-CSLMQCRLEYIDISSN 311
+ L +S+N+LQ +P C L +++ N
Sbjct: 244 MKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
Score = 52.8 bits (121), Expect = 1e-06
Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 18/154 (11%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV--RGVVDWRWL----------- 566
++L VLDLS N I ++PP G + L EL L+ N++ + + + L
Sbjct: 106 QNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDI 165
Query: 565 --LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L +++ LKL LDL+ N +P A+ + L L N + +LP TI R+ L
Sbjct: 166 CDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLH 225
Query: 397 YFTISSNELQSLPCSLMQCR-LEYIDISSNKFDN 299
+ NE+ LP ++ + L + +S+NK +
Sbjct: 226 TLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQD 259
Score = 33.1 bits (72), Expect = 1.2
Identities = 18/62 (29%), Positives = 35/62 (56%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L +L+L ++ + I +K+L L LSNN+++ +P MANL ++ +N L
Sbjct: 222 QNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Query: 595 VR 590
++
Sbjct: 282 LK 283
>AL445928-5|CAH72253.1| 335|Homo sapiens leucine rich repeat
containing 39 protein.
Length = 335
Score = 59.7 bits (138), Expect = 1e-08
Identities = 48/155 (30%), Positives = 73/155 (47%), Gaps = 2/155 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLS-NNEIEKLPPEFGRMANLSELHLANNQLGV 593
LQ L LS K+ +++ L L+L+ N +I LP E + L+ L L+ N
Sbjct: 131 LQELILSYNKIKTVPKELSNCASLEKLELAVNRDICDLPQELSNLLKLTHLDLSMNDFTT 190
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+ L P L+ LD+ SNKL LP I +++ L TL N I+ LP TI
Sbjct: 191 ---IPLAVLNMP----ALEWLDMGSNKLEQLPDTIERMQNLHTLWLQRNEITCLPQTISN 243
Query: 412 ISTLRYFTISSNELQSLP-CSLMQCRLEYIDISSN 311
+ L +S+N+LQ +P C L +++ N
Sbjct: 244 MKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDN 278
Score = 52.8 bits (121), Expect = 1e-06
Identities = 44/154 (28%), Positives = 74/154 (48%), Gaps = 18/154 (11%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV--RGVVDWRWL----------- 566
++L VLDLS N I ++PP G + L EL L+ N++ + + + L
Sbjct: 106 QNLIVLDLSRNTISEIPPGIGLLTRLQELILSYNKIKTVPKELSNCASLEKLELAVNRDI 165
Query: 565 --LGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
L +++ LKL LDL+ N +P A+ + L L N + +LP TI R+ L
Sbjct: 166 CDLPQELSNLLKLTHLDLSMNDFTTIPLAVLNMPALEWLDMGSNKLEQLPDTIERMQNLH 225
Query: 397 YFTISSNELQSLPCSLMQCR-LEYIDISSNKFDN 299
+ NE+ LP ++ + L + +S+NK +
Sbjct: 226 TLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQD 259
Score = 33.1 bits (72), Expect = 1.2
Identities = 18/62 (29%), Positives = 35/62 (56%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L +L+L ++ + I +K+L L LSNN+++ +P MANL ++ +N L
Sbjct: 222 QNLHTLWLQRNEITCLPQTISNMKNLGTLVLSNNKLQDIPVCMEEMANLRFVNFRDNPLK 281
Query: 595 VR 590
++
Sbjct: 282 LK 283
>BC018529-1|AAH18529.3| 683|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 4 protein.
Length = 683
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/135 (33%), Positives = 68/135 (50%), Gaps = 1/135 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT-LKL 533
L L L L +N + L P G + L+ L+L+ NQL LL P I + L++
Sbjct: 90 LVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLS---------LLPPYICQLPLRV 140
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L +++NKLG LP I L L L + N + LP+ + +S+LR + N+L +LP
Sbjct: 141 LIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTLPEE 200
Query: 352 LMQCRLEYIDISSNK 308
L L +D S N+
Sbjct: 201 LGDLPLVRLDFSCNR 215
Score = 54.0 bits (124), Expect = 6e-07
Identities = 38/117 (32%), Positives = 64/117 (54%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 521
L VL +SNN++ LPP+ G + +L +L +++N+L L G +L+ L++
Sbjct: 138 LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSE----LCG---LSSLRDLNVR 190
Query: 520 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
N+L LP+ + L LV L + N +SR+P + R+ L+ + SN LQS P +
Sbjct: 191 RNQLSTLPEELGDLP-LVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQV 246
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 2/134 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ L +S KL DI L L LD+S+NE++ LP E +++L +L++ NQL
Sbjct: 138 LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTL 197
Query: 589 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
P+ L L LD + N++ +P + +L L + + N + PA +
Sbjct: 198 ----------PEELGDLPLVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQVC 247
Query: 415 RISTLRYFTISSNE 374
L F S E
Sbjct: 248 LKGKLHIFKYLSTE 261
Score = 44.0 bits (99), Expect = 6e-04
Identities = 23/74 (31%), Positives = 38/74 (51%)
Frame = -2
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
DL+ N+ +P+A +L L L N + L +G ++ L Y +S N+L LP +
Sbjct: 74 DLSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLSLLPPYI 133
Query: 349 MQCRLEYIDISSNK 308
Q L + +S+NK
Sbjct: 134 CQLPLRVLIVSNNK 147
>BC009239-1|AAH09239.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
Frame = -2
Query: 556 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 377
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 376 ELQSLPCSLMQCR-LEYIDISSN 311
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 2e-07
Identities = 35/116 (30%), Positives = 62/116 (53%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = -2
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 364 LPCSLMQCR-LEYIDISSNK 308
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.041
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 368
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 367 SLPCSLMQ-CRLEYIDISSNK 308
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
>AY358830-1|AAQ89189.1| 723|Homo sapiens leucine-rich protein
protein.
Length = 723
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
Frame = -2
Query: 556 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 377
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 376 ELQSLPCSLMQCR-LEYIDISSN 311
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 2e-07
Identities = 35/116 (30%), Positives = 62/116 (53%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = -2
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 364 LPCSLMQCR-LEYIDISSNK 308
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.041
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 368
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 367 SLPCSLMQ-CRLEYIDISSNK 308
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
>AL445222-17|CAH72931.1| 696|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 696
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
Frame = -2
Query: 556 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 377
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 376 ELQSLPCSLMQCR-LEYIDISSN 311
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 2e-07
Identities = 35/116 (30%), Positives = 62/116 (53%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = -2
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 364 LPCSLMQCR-LEYIDISSNK 308
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.041
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 368
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 367 SLPCSLMQ-CRLEYIDISSNK 308
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
>AL445222-16|CAH72930.1| 723|Homo sapiens leucine rich repeat and
sterile alpha motif containing 1 protein.
Length = 723
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
Frame = -2
Query: 556 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 377
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 376 ELQSLPCSLMQCR-LEYIDISSN 311
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 2e-07
Identities = 35/116 (30%), Positives = 62/116 (53%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = -2
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 364 LPCSLMQCR-LEYIDISSNK 308
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.041
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 368
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 367 SLPCSLMQ-CRLEYIDISSNK 308
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
>AK091589-1|BAC03703.1| 723|Homo sapiens protein ( Homo sapiens
cDNA FLJ34270 fis, clone FEBRA2003100. ).
Length = 723
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
Frame = -2
Query: 556 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 377
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 376 ELQSLPCSLMQCR-LEYIDISSN 311
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 2e-07
Identities = 35/116 (30%), Positives = 62/116 (53%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = -2
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 364 LPCSLMQCR-LEYIDISSNK 308
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.041
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 368
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 367 SLPCSLMQ-CRLEYIDISSNK 308
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
>AK056203-1|BAB71119.1| 696|Homo sapiens protein ( Homo sapiens
cDNA FLJ31641 fis, clone NT2RI2003695, weakly similar to
TRICHOHYALIN. ).
Length = 696
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/83 (38%), Positives = 50/83 (60%), Gaps = 1/83 (1%)
Frame = -2
Query: 556 QITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 377
Q+T L++L++ N+L LP++I L +L TL DN + LP T+G + +LR IS N
Sbjct: 102 QLT-ALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKELPDTVGELRSLRTLNISGN 160
Query: 376 ELQSLPCSLMQCR-LEYIDISSN 311
E+Q LP L R LE + + ++
Sbjct: 161 EIQRLPQMLAHVRTLEMLSLDAS 183
Score = 55.2 bits (127), Expect = 2e-07
Identities = 35/116 (30%), Positives = 62/116 (53%)
Frame = -2
Query: 718 ILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
+L L + VLDL +N++ LP + G++ L L++ NQL + +G +T+ L
Sbjct: 77 LLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQL-----MQLPRSIG-NLTQ-L 129
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
+ L++ NKL LP + +L L TL + N I RLP + + TL ++ ++ +
Sbjct: 130 QTLNVKDNKLKELPDTVGELRSLRTLNISGNEIQRLPQMLAHVRTLEMLSLDASAM 185
Score = 51.6 bits (118), Expect = 3e-06
Identities = 27/80 (33%), Positives = 47/80 (58%), Gaps = 1/80 (1%)
Frame = -2
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
T+K+LDL N+L LP + +L L L N + +LP +IG ++ L+ + N+L+
Sbjct: 82 TIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLMQLPRSIGNLTQLQTLNVKDNKLKE 141
Query: 364 LPCSLMQCR-LEYIDISSNK 308
LP ++ + R L ++IS N+
Sbjct: 142 LPDTVGELRSLRTLNISGNE 161
Score = 37.9 bits (84), Expect = 0.041
Identities = 23/81 (28%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKA---NDNMISRLPATIGRISTLRYFTISSNELQ 368
K+L + +N L L L L T+K +DN ++ LP +G+++ L+ + N+L
Sbjct: 58 KVLIVHTNHLTSLLPKSCSLLSLATIKVLDLHDNQLTALPDDLGQLTALQVLNVERNQLM 117
Query: 367 SLPCSLMQ-CRLEYIDISSNK 308
LP S+ +L+ +++ NK
Sbjct: 118 QLPRSIGNLTQLQTLNVKDNK 138
>AF053356-12|AAC78793.1| 832|Homo sapiens leucin rich neuronal
protein protein.
Length = 832
Score = 59.3 bits (137), Expect = 2e-08
Identities = 45/135 (33%), Positives = 68/135 (50%), Gaps = 1/135 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT-LKL 533
L L L L +N + L P G + L+ L+L+ NQL LL P I + L++
Sbjct: 90 LVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLS---------LLPPYICQLPLRV 140
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L +++NKLG LP I L L L + N + LP+ + +S+LR + N+L +LP
Sbjct: 141 LIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTLPEE 200
Query: 352 LMQCRLEYIDISSNK 308
L L +D S N+
Sbjct: 201 LGDLPLVRLDFSCNR 215
Score = 54.0 bits (124), Expect = 6e-07
Identities = 38/117 (32%), Positives = 64/117 (54%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 521
L VL +SNN++ LPP+ G + +L +L +++N+L L G +L+ L++
Sbjct: 138 LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSE----LCG---LSSLRDLNVR 190
Query: 520 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
N+L LP+ + L LV L + N +SR+P + R+ L+ + SN LQS P +
Sbjct: 191 RNQLSTLPEELGDLP-LVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQV 246
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 2/134 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ L +S KL DI L L LD+S+NE++ LP E +++L +L++ NQL
Sbjct: 138 LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTL 197
Query: 589 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
P+ L L LD + N++ +P + +L L + + N + PA +
Sbjct: 198 ----------PEELGDLPLVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQVC 247
Query: 415 RISTLRYFTISSNE 374
L F S E
Sbjct: 248 LKGKLHIFKYLSTE 261
Score = 44.0 bits (99), Expect = 6e-04
Identities = 23/74 (31%), Positives = 38/74 (51%)
Frame = -2
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
DL+ N+ +P+A +L L L N + L +G ++ L Y +S N+L LP +
Sbjct: 74 DLSRNRFPEVPEAACQLVSLEGLSLYHNCLRCLNPALGNLTALTYLNLSRNQLSLLPPYI 133
Query: 349 MQCRLEYIDISSNK 308
Q L + +S+NK
Sbjct: 134 CQLPLRVLIVSNNK 147
>AB016816-1|BAA74737.1| 1052|Homo sapiens MASL1 protein.
Length = 1052
Score = 59.3 bits (137), Expect = 2e-08
Identities = 42/155 (27%), Positives = 78/155 (50%), Gaps = 1/155 (0%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ L +S +L + + L L LD+ +N++ P + ++ L EL +++N+L R
Sbjct: 160 LEELDVSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRL--R 217
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
G+ + + LK+L L+ +LG LP +L L +L ++N + LPA +
Sbjct: 218 GLPE-----DISALRALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCL 272
Query: 409 STLRYFTISSNELQSLPCSLMQ-CRLEYIDISSNK 308
L+ +SSN + P +L+ LE + +S N+
Sbjct: 273 QRLKMLNLSSNLFEEFPAALLPLAGLEELYLSRNQ 307
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/116 (31%), Positives = 60/116 (51%), Gaps = 1/116 (0%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEF-GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
HL LD+S+N + L E + L +L+L++NQL LG L+ LD
Sbjct: 112 HLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQ-----LGA--LAHLEELD 164
Query: 526 LTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
++ N+L HLP ++ L +L TL + N ++ P + ++ L +SSN L+ LP
Sbjct: 165 VSFNRLAHLPDSLSCLSRLRTLDVDHNQLTAFPRQLLQLVALEELDVSSNRLRGLP 220
Score = 51.6 bits (118), Expect = 3e-06
Identities = 42/139 (30%), Positives = 68/139 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L+ L+LSG +L L L L L NN ++ LP +F + L L+L++N
Sbjct: 227 RALKILWLSGAELGTLPAGFCELASLESLMLDNNGLQALPAQFSCLQRLKMLNLSSNLF- 285
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
++ L P L+ L L+ N+L +P I L +L+TL ++N I LP +I
Sbjct: 286 ----EEFPAALLP--LAGLEELYLSRNQLTSVPSLISGLGRLLTLWLDNNRIRYLPDSIV 339
Query: 415 RISTLRYFTISSNELQSLP 359
++ L + N++ LP
Sbjct: 340 ELTGLEELVLQGNQIAVLP 358
Score = 44.0 bits (99), Expect = 6e-04
Identities = 36/119 (30%), Positives = 59/119 (49%), Gaps = 3/119 (2%)
Frame = -2
Query: 655 PEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKL- 479
P+ ANL ++ N LG G+ + LG + +L++L L N+ LP A+ +L
Sbjct: 54 PQLVLPANLGDIEALN--LGNNGLEEVPEGLGSALG-SLRVLVLRRNRFARLPPAVAELG 110
Query: 478 EKLVTLKANDNMISRLPA-TIGRISTLRYFTISSNELQSLPCSL-MQCRLEYIDISSNK 308
L L + N ++ L A + + LR +S N+L +LP L LE +D+S N+
Sbjct: 111 HHLTELDVSHNRLTALGAEVVSALRELRKLNLSHNQLPALPAQLGALAHLEELDVSFNR 169
>AK001637-1|BAA91801.1| 183|Homo sapiens protein ( Homo sapiens
cDNA FLJ10775 fis, clone NT2RP4000312, weakly similar to
ADENYLATE CYCLASE (EC 4.6.1.1). ).
Length = 183
Score = 58.8 bits (136), Expect = 2e-08
Identities = 44/144 (30%), Positives = 71/144 (49%), Gaps = 2/144 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
+ L L ++ + L + +I L +LA L+L N + LP ++ L EL L NN++
Sbjct: 47 QNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLTYLPDSLTQLRRLEELDLGNNEI- 105
Query: 595 VRGVVDWRWLLGPQITKTLKLLDL--TSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
+ L I L L DL N+L LP+ I L+ L+ L ++N + RLP
Sbjct: 106 --------YNLPESIGALLHLKDLWLDGNQLSELPQEIGNLKNLLCLDVSENRLERLPEE 157
Query: 421 IGRISTLRYFTISSNELQSLPCSL 350
I +++L IS N L+++P L
Sbjct: 158 ISGLTSLTDLVISQNLLETIPDGL 181
Score = 53.2 bits (122), Expect = 1e-06
Identities = 30/84 (35%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
K L++ D + N L LP++ +L+ L L ND + LP IG + L + N L
Sbjct: 24 KALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIGNLYNLASLELRENLLT 83
Query: 367 SLPCSLMQC-RLEYIDISSNKFDN 299
LP SL Q RLE +D+ +N+ N
Sbjct: 84 YLPDSLTQLRRLEELDLGNNEIYN 107
Score = 33.9 bits (74), Expect = 0.66
Identities = 16/58 (27%), Positives = 32/58 (55%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
LD++ N++ +P++I + L + N ++RLP + + L +++ LQSLP
Sbjct: 6 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLP 63
>AL513211-2|CAI17359.1| 154|Homo sapiens leucine rich repeat
containing 1 protein.
Length = 154
Score = 58.4 bits (135), Expect = 3e-08
Identities = 38/124 (30%), Positives = 59/124 (47%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ L L +L L L L LS+NEI++LPPE L EL ++ N+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNE-- 93
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + K L++ D + N L LP++ +L+ L L ND + LP IG
Sbjct: 94 IPEIPE-----SISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLPENIG 148
Query: 415 RIST 404
+ T
Sbjct: 149 KQKT 152
Score = 49.6 bits (113), Expect = 1e-05
Identities = 29/80 (36%), Positives = 44/80 (55%), Gaps = 1/80 (1%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
++L+ L L +N+L LP+ ++L KL L +DN I RLP I L +S NE+
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQRLPPEIANFMQLVELDVSRNEIP 95
Query: 367 SLPCSLMQCR-LEYIDISSN 311
+P S+ C+ L+ D S N
Sbjct: 96 EIPESISFCKALQVADFSGN 115
Score = 46.4 bits (105), Expect = 1e-04
Identities = 31/118 (26%), Positives = 62/118 (52%), Gaps = 2/118 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL-- 533
+ L L L N++ +LP +F ++ L +L L++N++ L P+I ++L
Sbjct: 36 RSLEELLLDANQLRELPEQFFQLVKLRKLGLSDNEIQ---------RLPPEIANFMQLVE 86
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
LD++ N++ +P++I + L + N ++RLP + + L +++ LQSLP
Sbjct: 87 LDVSRNEIPEIPESISFCKALQVADFSGNPLTRLPESFPELQNLTCLSVNDISLQSLP 144
>J05158-1|AAA51921.2| 545|Homo sapiens carboxypeptidase N precursor
protein.
Length = 545
Score = 57.6 bits (133), Expect = 5e-08
Identities = 51/144 (35%), Positives = 72/144 (50%), Gaps = 4/144 (2%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANN 605
PR L+ L ++G N +I L L L L+ N +E LP F +A L LHL N
Sbjct: 97 PR-LEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGN 155
Query: 604 QLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLP 428
QL R L P +T LK L+L N L LP+ ++ L L TLK ++N +S LP
Sbjct: 156 QLQALP----RRLFQP-LTH-LKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLP 209
Query: 427 -ATIGRISTLRYFTISSNELQSLP 359
G++ +L+ + SN + LP
Sbjct: 210 QGVFGKLGSLQELFLDSNNISELP 233
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L +L L L N + LP F L L L +NQL + L L+
Sbjct: 264 LGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHL------SNLRS 317
Query: 532 LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 359
L L+ N + HLP I++ LE+LV L N ++ L PA +S L ++S N+L +LP
Sbjct: 318 LMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLP 377
>BC031569-1|AAH31569.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 57.6 bits (133), Expect = 5e-08
Identities = 51/144 (35%), Positives = 72/144 (50%), Gaps = 4/144 (2%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANN 605
PR L+ L ++G N +I L L L L+ N +E LP F +A L LHL N
Sbjct: 97 PR-LEDLEVTGSSFLNLSTNIFSNLTSLGKLTLNFNMLEALPEGLFQHLAALESLHLQGN 155
Query: 604 QLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLP 428
QL R L P +T LK L+L N L LP+ ++ L L TLK ++N +S LP
Sbjct: 156 QLQALP----RRLFQP-LTH-LKTLNLAQNLLAQLPEELFHPLTSLQTLKLSNNALSGLP 209
Query: 427 -ATIGRISTLRYFTISSNELQSLP 359
G++ +L+ + SN + LP
Sbjct: 210 QGVFGKLGSLQELFLDSNNISELP 233
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L +L L L N + LP F L L L +NQL + L L+
Sbjct: 264 LGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHL------SNLRS 317
Query: 532 LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 359
L L+ N + HLP I++ LE+LV L N ++ L PA +S L ++S N+L +LP
Sbjct: 318 LMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLP 377
>AF229178-1|AAF69491.1| 753|Homo sapiens leucine rich repeat and
death domain containing protein protein.
Length = 753
Score = 57.2 bits (132), Expect = 6e-08
Identities = 43/145 (29%), Positives = 70/145 (48%), Gaps = 2/145 (1%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L +L LS L + L L L +++N ++ LPP G ++ L L L+ N L
Sbjct: 2 RGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPALGALSTLQRLDLSQNLLD 61
Query: 595 VRGVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPAT 422
L P+I +L L+L SN+L LP ++ L L L + N+++ +PA
Sbjct: 62 T---------LPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPAD 112
Query: 421 IGRISTLRYFTISSNELQSLPCSLM 347
+ R+ L + N+L+ LP L+
Sbjct: 113 LARLPLLTRLDLRDNQLRDLPPELL 137
Score = 54.0 bits (124), Expect = 6e-07
Identities = 42/135 (31%), Positives = 66/135 (48%), Gaps = 1/135 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
++ L L LS+N + +LP G + L+ L + +N+L LG TL+ L
Sbjct: 1 MRGLGALLLSHNCLSELPEALGALPALTFLTVTHNRLQTLPPA-----LGA--LSTLQRL 53
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
DL+ N L LP I L L+ L N + LPA++ + +LR + SN L S+P L
Sbjct: 54 DLSQNLLDTLPPEIGGLGSLLELNLASNRLQSLPASLAGLRSLRLLVLHSNLLASVPADL 113
Query: 349 MQC-RLEYIDISSNK 308
+ L +D+ N+
Sbjct: 114 ARLPLLTRLDLRDNQ 128
>AY358137-1|AAQ88504.1| 255|Homo sapiens VKGE9338 protein.
Length = 255
Score = 56.8 bits (131), Expect = 8e-08
Identities = 33/111 (29%), Positives = 64/111 (57%), Gaps = 1/111 (0%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLKLL 530
++L LDL +N I+KLP G+M +L L+++NN+L G+ V+ + L K ++ +
Sbjct: 73 QNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQL------KNIRAV 126
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 377
+L N L +P + L++L + +DN+++ +P +I ++ L+ I N
Sbjct: 127 NLGLNHLDSVPTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRN 177
Score = 50.8 bits (116), Expect = 5e-06
Identities = 43/155 (27%), Positives = 77/155 (49%), Gaps = 3/155 (1%)
Frame = -2
Query: 760 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 581
L LS + + F + IL L + LDLS N I K+P + NL L L +N +
Sbjct: 32 LDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYID----- 86
Query: 580 DWRWLLGPQITKTLKLLDLTSNKL--GHLPKAIWKLEKLVTLKANDNMISRLPATIGRIS 407
+G Q+T +L L++++N+L LP + +L+ + + N + +P T+G +
Sbjct: 87 KLPESIG-QMT-SLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVPTTLGALK 144
Query: 406 TLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKF 305
L + N L ++P S+ + +L+ ++I N F
Sbjct: 145 ELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPF 179
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/81 (33%), Positives = 47/81 (58%), Gaps = 3/81 (3%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS--LP 359
LDL+ N + +P +I K + L L + N I +LP +IG++++L Y +S+N L S LP
Sbjct: 55 LDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLP 114
Query: 358 CSLMQCR-LEYIDISSNKFDN 299
L Q + + +++ N D+
Sbjct: 115 VELKQLKNIRAVNLGLNHLDS 135
Score = 47.2 bits (107), Expect = 7e-05
Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
K LDL+ + PK I +L + L + N+I ++P +I + LR+ + SN + LP
Sbjct: 30 KRLDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLP 89
Query: 358 CSLMQ-CRLEYIDISSNK 308
S+ Q L Y+++S+N+
Sbjct: 90 ESIGQMTSLLYLNVSNNR 107
>AJ308569-1|CAC33442.1| 371|Homo sapiens leucine-rich
repeat-containing 2 protein protein.
Length = 371
Score = 56.8 bits (131), Expect = 8e-08
Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 1/138 (0%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ Y+S + I L + + +LDL N+I LP E G + NL EL++ N L +
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQEMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYL--K 180
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSN-KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+ LG + L+ LD + N +L LP + L+++ + + N S +P + R
Sbjct: 181 SIPP---ELGD--CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLR 235
Query: 412 ISTLRYFTISSNELQSLP 359
+S L++ ISSN L LP
Sbjct: 236 MSNLQWLDISSNNLTDLP 253
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 3/141 (2%)
Frame = -2
Query: 706 KHLAVLDLSNN-EIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
++L LD S N E+ +LP E + ++ + ++ N+ + R L+ L
Sbjct: 190 ENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRM-------SNLQWL 242
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
D++SN L LP+ I +LE+L + N ++ LP ++ + L +S + L LP +L
Sbjct: 243 DISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLVELPTAL 302
Query: 349 MQCR--LEYIDISSNKFDNKQ 293
L+++ + N DN Q
Sbjct: 303 CDSSTPLKFVSLMDNPIDNAQ 323
Score = 40.3 bits (90), Expect = 0.008
Identities = 23/65 (35%), Positives = 33/65 (50%), Gaps = 1/65 (1%)
Frame = -2
Query: 502 LPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC-RLEYI 326
+P I +++ L N IS LPA IG + L+ + N L+S+P L C LE +
Sbjct: 136 IPTYIQLFQEMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERL 195
Query: 325 DISSN 311
D S N
Sbjct: 196 DCSGN 200
>BC029118-1|AAH29118.1| 371|Homo sapiens leucine rich repeat
containing 2 protein.
Length = 371
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 2/134 (1%)
Frame = -2
Query: 694 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
V +LS +LP +L E +++N + + Q+ + +++LDL N
Sbjct: 102 VFELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYI-------QLFQAMRILDLPKN 154
Query: 514 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN-ELQSLPCSLMQCR 338
++ HLP I L+ L L N + +P +G L S N EL LP L +
Sbjct: 155 QISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLK 214
Query: 337 -LEYIDISSNKFDN 299
+ ++DIS+NKF +
Sbjct: 215 QVTFVDISANKFSS 228
Score = 56.0 bits (129), Expect = 1e-07
Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 1/138 (0%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ Y+S + I L + + +LDL N+I LP E G + NL EL++ N L +
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYL--K 180
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSN-KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+ LG + L+ LD + N +L LP + L+++ + + N S +P + R
Sbjct: 181 SIPP---ELGD--CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLR 235
Query: 412 ISTLRYFTISSNELQSLP 359
+S L++ ISSN L LP
Sbjct: 236 MSNLQWLDISSNNLTDLP 253
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 3/141 (2%)
Frame = -2
Query: 706 KHLAVLDLSNN-EIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
++L LD S N E+ +LP E + ++ + ++ N+ + R L+ L
Sbjct: 190 ENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRM-------SNLQWL 242
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
D++SN L LP+ I +LE+L + N ++ LP ++ + L +S + L LP +L
Sbjct: 243 DISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLVELPTAL 302
Query: 349 MQCR--LEYIDISSNKFDNKQ 293
L+++ + N DN Q
Sbjct: 303 CDSSTPLKFVSLMDNPIDNAQ 323
>AK223440-1|BAD97160.1| 371|Homo sapiens leucine rich repeat
containing 2 variant protein.
Length = 371
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 2/134 (1%)
Frame = -2
Query: 694 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
V +LS +LP +L E +++N + + Q+ + +++LDL N
Sbjct: 102 VFELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYI-------QLFQAMRILDLPKN 154
Query: 514 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN-ELQSLPCSLMQCR 338
++ HLP I L+ L L N + +P +G L S N EL LP L +
Sbjct: 155 QISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLK 214
Query: 337 -LEYIDISSNKFDN 299
+ ++DIS+NKF +
Sbjct: 215 QVTFVDISANKFSS 228
Score = 56.0 bits (129), Expect = 1e-07
Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 1/138 (0%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ Y+S + I L + + +LDL N+I LP E G + NL EL++ N L +
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYL--K 180
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSN-KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+ LG + L+ LD + N +L LP + L+++ + + N S +P + R
Sbjct: 181 SIPP---ELGD--CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLR 235
Query: 412 ISTLRYFTISSNELQSLP 359
+S L++ ISSN L LP
Sbjct: 236 MSNLQWLDISSNNLTDLP 253
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 3/141 (2%)
Frame = -2
Query: 706 KHLAVLDLSNN-EIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
++L LD S N E+ +LP E + ++ + ++ N+ + R L+ L
Sbjct: 190 ENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRM-------SNLQWL 242
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
D++SN L LP+ I +LE+L + N ++ LP ++ + L +S + L LP +L
Sbjct: 243 DISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLVELPTAL 302
Query: 349 MQCR--LEYIDISSNKFDNKQ 293
L+++ + N DN Q
Sbjct: 303 CDSSTPLKFVSLMDNPIDNAQ 323
>AK057808-1|BAB71585.1| 371|Homo sapiens protein ( Homo sapiens
cDNA FLJ25079 fis, clone CBL07055. ).
Length = 371
Score = 56.4 bits (130), Expect = 1e-07
Identities = 37/134 (27%), Positives = 62/134 (46%), Gaps = 2/134 (1%)
Frame = -2
Query: 694 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
V +LS +LP +L E +++N + + Q+ + +++LDL N
Sbjct: 102 VFELSGEHWTELPDSLKEQTHLREWYISNTLIQIIPTYI-------QLFQAMRILDLPKN 154
Query: 514 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN-ELQSLPCSLMQCR 338
++ HLP I L+ L L N + +P +G L S N EL LP L +
Sbjct: 155 QISHLPAEIGCLKNLKELNVGFNYLKSIPPELGDCENLERLDCSGNLELMELPFELSNLK 214
Query: 337 -LEYIDISSNKFDN 299
+ ++DIS+NKF +
Sbjct: 215 QVTFVDISANKFSS 228
Score = 56.0 bits (129), Expect = 1e-07
Identities = 43/138 (31%), Positives = 70/138 (50%), Gaps = 1/138 (0%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ Y+S + I L + + +LDL N+I LP E G + NL EL++ N L +
Sbjct: 123 LREWYISNTLIQIIPTYIQLFQAMRILDLPKNQISHLPAEIGCLKNLKELNVGFNYL--K 180
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSN-KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+ LG + L+ LD + N +L LP + L+++ + + N S +P + R
Sbjct: 181 SIPP---ELGD--CENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLR 235
Query: 412 ISTLRYFTISSNELQSLP 359
+S L++ ISSN L LP
Sbjct: 236 MSNLQWLDISSNNLTDLP 253
Score = 48.8 bits (111), Expect = 2e-05
Identities = 37/141 (26%), Positives = 68/141 (48%), Gaps = 3/141 (2%)
Frame = -2
Query: 706 KHLAVLDLSNN-EIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
++L LD S N E+ +LP E + ++ + ++ N+ + R L+ L
Sbjct: 190 ENLERLDCSGNLELMELPFELSNLKQVTFVDISANKFSSVPICVLRM-------SNLQWL 242
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
D++SN L LP+ I +LE+L + N ++ LP ++ + L +S + L LP +L
Sbjct: 243 DISSNNLTDLPQDIDRLEELQSFLLYKNKLTYLPYSMLNLKKLTLLVVSGDHLVELPTAL 302
Query: 349 MQCR--LEYIDISSNKFDNKQ 293
L+++ + N DN Q
Sbjct: 303 CDSSTPLKFVSLMDNPIDNAQ 323
>BC052279-1|AAH52279.1| 307|Homo sapiens leucine rich repeat
containing 59 protein.
Length = 307
Score = 56.0 bits (129), Expect = 1e-07
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Frame = -2
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
+LDL+ NKL LP L LV L + N + +LPA GR+ L++ + +N+L +LP
Sbjct: 43 ILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPV 102
Query: 355 SLMQCR-LEYIDISSNKFD 302
S Q + L+++D+ N D
Sbjct: 103 SFAQLKNLKWLDLKDNPLD 121
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/84 (44%), Positives = 45/84 (53%)
Frame = -2
Query: 760 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 581
L LS KL D L HL LDLS N++++LP +FGR+ NL L L NN+L V V
Sbjct: 44 LDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKL-VTLPV 102
Query: 580 DWRWLLGPQITKTLKLLDLTSNKL 509
+ L K LK LDL N L
Sbjct: 103 SFAQL------KNLKWLDLKDNPL 120
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/102 (30%), Positives = 54/102 (52%)
Frame = -2
Query: 724 RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITK 545
+++ L +LDLS N++ LP +F + +L +L L+ N+L + D+ L+
Sbjct: 33 KELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQ-QLPADFGRLVN----- 86
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 419
L+ LDL +NKL LP + +L+ L L DN + + A +
Sbjct: 87 -LQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKV 127
Score = 34.7 bits (76), Expect = 0.38
Identities = 23/57 (40%), Positives = 29/57 (50%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
L L LS KL D L +L LDL NN++ LP F ++ NL L L +N L
Sbjct: 64 LVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPL 120
>BC051322-1|AAH51322.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 56.0 bits (129), Expect = 1e-07
Identities = 36/125 (28%), Positives = 64/125 (51%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 661 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 713
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 714 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 773
Query: 349 MQCRL 335
+C L
Sbjct: 774 GECPL 778
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 566
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 590 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query: 565 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 650 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 709
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L+ I++N +++LP L QCR L + + +N
Sbjct: 710 LQNLAITANRIETLPPELFQCRKLRALHLGNN 741
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 664 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 722
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L P++ + L+ L L +N L LP + +L L ++ N + LP +G
Sbjct: 723 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 415 RISTLR 398
L+
Sbjct: 775 ECPLLK 780
Score = 41.1 bits (92), Expect = 0.004
Identities = 26/59 (44%), Positives = 32/59 (54%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 685 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 743
>BC017168-1|AAH17168.1| 307|Homo sapiens leucine rich repeat
containing 59 protein.
Length = 307
Score = 56.0 bits (129), Expect = 1e-07
Identities = 29/79 (36%), Positives = 46/79 (58%), Gaps = 1/79 (1%)
Frame = -2
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
+LDL+ NKL LP L LV L + N + +LPA GR+ L++ + +N+L +LP
Sbjct: 43 ILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPV 102
Query: 355 SLMQCR-LEYIDISSNKFD 302
S Q + L+++D+ N D
Sbjct: 103 SFAQLKNLKWLDLKDNPLD 121
Score = 52.8 bits (121), Expect = 1e-06
Identities = 37/84 (44%), Positives = 45/84 (53%)
Frame = -2
Query: 760 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 581
L LS KL D L HL LDLS N++++LP +FGR+ NL L L NN+L V V
Sbjct: 44 LDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKL-VTLPV 102
Query: 580 DWRWLLGPQITKTLKLLDLTSNKL 509
+ L K LK LDL N L
Sbjct: 103 SFAQL------KNLKWLDLKDNPL 120
Score = 40.7 bits (91), Expect = 0.006
Identities = 31/102 (30%), Positives = 54/102 (52%)
Frame = -2
Query: 724 RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITK 545
+++ L +LDLS N++ LP +F + +L +L L+ N+L + D+ L+
Sbjct: 33 KELAALPKATILDLSCNKLTTLPSDFCGLTHLVKLDLSKNKLQ-QLPADFGRLVN----- 86
Query: 544 TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 419
L+ LDL +NKL LP + +L+ L L DN + + A +
Sbjct: 87 -LQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPLDPVLAKV 127
Score = 34.7 bits (76), Expect = 0.38
Identities = 23/57 (40%), Positives = 29/57 (50%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
L L LS KL D L +L LDL NN++ LP F ++ NL L L +N L
Sbjct: 64 LVKLDLSKNKLQQLPADFGRLVNLQHLDLLNNKLVTLPVSFAQLKNLKWLDLKDNPL 120
>AY358286-1|AAQ88653.1| 546|Homo sapiens RQTI221 protein.
Length = 546
Score = 56.0 bits (129), Expect = 1e-07
Identities = 36/125 (28%), Positives = 64/125 (51%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 397 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 449
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 450 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 509
Query: 349 MQCRL 335
+C L
Sbjct: 510 GECPL 514
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 566
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 326 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 385
Query: 565 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 386 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 445
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L+ I++N +++LP L QCR L + + +N
Sbjct: 446 LQNLAITANRIETLPPELFQCRKLRALHLGNN 477
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 400 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 458
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L P++ + L+ L L +N L LP + +L L ++ N + LP +G
Sbjct: 459 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 510
Query: 415 RISTLR 398
L+
Sbjct: 511 ECPLLK 516
Score = 41.1 bits (92), Expect = 0.004
Identities = 26/59 (44%), Positives = 32/59 (54%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 421 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 479
>AY143166-1|AAN18279.1| 810|Homo sapiens leucine-rich
repeat-containing 8 protein.
Length = 810
Score = 56.0 bits (129), Expect = 1e-07
Identities = 36/125 (28%), Positives = 64/125 (51%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 661 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 713
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 714 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 773
Query: 349 MQCRL 335
+C L
Sbjct: 774 GECPL 778
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 566
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 590 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query: 565 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 650 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 709
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L+ I++N +++LP L QCR L + + +N
Sbjct: 710 LQNLAITANRIETLPPELFQCRKLRALHLGNN 741
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 664 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 722
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L P++ + L+ L L +N L LP + +L L ++ N + LP +G
Sbjct: 723 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 415 RISTLR 398
L+
Sbjct: 775 ECPLLK 780
Score = 41.1 bits (92), Expect = 0.004
Identities = 26/59 (44%), Positives = 32/59 (54%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 685 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 743
>AL672142-1|CAI10839.1| 810|Homo sapiens leucine rich repeat
containing 8 family, member A protein.
Length = 810
Score = 56.0 bits (129), Expect = 1e-07
Identities = 36/125 (28%), Positives = 64/125 (51%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 661 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 713
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 714 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 773
Query: 349 MQCRL 335
+C L
Sbjct: 774 GECPL 778
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 566
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 590 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 649
Query: 565 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 650 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 709
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L+ I++N +++LP L QCR L + + +N
Sbjct: 710 LQNLAITANRIETLPPELFQCRKLRALHLGNN 741
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 664 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 722
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L P++ + L+ L L +N L LP + +L L ++ N + LP +G
Sbjct: 723 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 774
Query: 415 RISTLR 398
L+
Sbjct: 775 ECPLLK 780
Score = 41.1 bits (92), Expect = 0.004
Identities = 26/59 (44%), Positives = 32/59 (54%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 685 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 743
>AK027495-1|BAB55153.1| 474|Homo sapiens protein ( Homo sapiens
cDNA FLJ14589 fis, clone NT2RM4001876, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 474
Score = 56.0 bits (129), Expect = 1e-07
Identities = 36/125 (28%), Positives = 64/125 (51%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 325 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 377
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 378 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 437
Query: 349 MQCRL 335
+C L
Sbjct: 438 GECPL 442
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 566
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 254 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 313
Query: 565 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 314 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 373
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L+ I++N +++LP L QCR L + + +N
Sbjct: 374 LQNLAITANRIETLPPELFQCRKLRALHLGNN 405
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 328 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 386
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L P++ + L+ L L +N L LP + +L L ++ N + LP +G
Sbjct: 387 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 438
Query: 415 RISTLR 398
L+
Sbjct: 439 ECPLLK 444
Score = 41.1 bits (92), Expect = 0.004
Identities = 26/59 (44%), Positives = 32/59 (54%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 349 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 407
>AK001199-1|BAA91549.1| 221|Homo sapiens protein ( Homo sapiens
cDNA FLJ10337 fis, clone NT2RM2000714, weakly similar to
RAS SUPPRESSOR PROTEIN 1. ).
Length = 221
Score = 56.0 bits (129), Expect = 1e-07
Identities = 36/125 (28%), Positives = 64/125 (51%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 72 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 124
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 125 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 184
Query: 349 MQCRL 335
+C L
Sbjct: 185 GECPL 189
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 75 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 133
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L P++ + L+ L L +N L LP + +L L ++ N + LP +G
Sbjct: 134 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 185
Query: 415 RISTLR 398
L+
Sbjct: 186 ECPLLK 191
Score = 48.4 bits (110), Expect = 3e-05
Identities = 26/78 (33%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Frame = -2
Query: 541 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L+ L L NK+ +P ++ KL L + N ++ LPA IG + L+ I++N +++L
Sbjct: 75 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETL 134
Query: 361 PCSLMQCR-LEYIDISSN 311
P L QCR L + + +N
Sbjct: 135 PPELFQCRKLRALHLGNN 152
Score = 41.1 bits (92), Expect = 0.004
Identities = 26/59 (44%), Positives = 32/59 (54%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 96 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 154
>AB037858-1|BAA92675.1| 811|Homo sapiens KIAA1437 protein protein.
Length = 811
Score = 56.0 bits (129), Expect = 1e-07
Identities = 36/125 (28%), Positives = 64/125 (51%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 662 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 714
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 715 AITANRIETLPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVEL 774
Query: 349 MQCRL 335
+C L
Sbjct: 775 GECPL 779
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 566
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 591 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 650
Query: 565 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 651 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 710
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L+ I++N +++LP L QCR L + + +N
Sbjct: 711 LQNLAITANRIETLPPELFQCRKLRALHLGNN 742
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 665 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 723
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L P++ + L+ L L +N L LP + +L L ++ N + LP +G
Sbjct: 724 --------LPPELFQCRKLRALHLGNNVLQSLPSRVGELTNLTQIELRGNRLECLPVELG 775
Query: 415 RISTLR 398
L+
Sbjct: 776 ECPLLK 781
Score = 41.1 bits (92), Expect = 0.004
Identities = 26/59 (44%), Positives = 32/59 (54%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 686 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 744
>BC007634-1|AAH07634.1| 580|Homo sapiens LRCH4 protein protein.
Length = 580
Score = 55.6 bits (128), Expect = 2e-07
Identities = 40/119 (33%), Positives = 61/119 (51%), Gaps = 1/119 (0%)
Frame = -2
Query: 661 LPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKT-LKLLDLTSNKLGHLPKAIW 485
L P G + L+ L+L+ NQL LL P I + L++L +++NKLG LP I
Sbjct: 3 LNPALGNLTALTYLNLSRNQLS---------LLPPYICQLPLRVLIVSNNKLGALPPDIG 53
Query: 484 KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 308
L L L + N + LP+ + +S+LR + N+L +LP L L +D S N+
Sbjct: 54 TLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTLPEELGDLPLVRLDFSCNR 112
Score = 54.0 bits (124), Expect = 6e-07
Identities = 38/117 (32%), Positives = 64/117 (54%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 521
L VL +SNN++ LPP+ G + +L +L +++N+L L G +L+ L++
Sbjct: 35 LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSE----LCG---LSSLRDLNVR 87
Query: 520 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
N+L LP+ + L LV L + N +SR+P + R+ L+ + SN LQS P +
Sbjct: 88 RNQLSTLPEELGDLP-LVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQV 143
Score = 45.2 bits (102), Expect = 3e-04
Identities = 38/134 (28%), Positives = 61/134 (45%), Gaps = 2/134 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ L +S KL DI L L LD+S+NE++ LP E +++L +L++ NQL
Sbjct: 35 LRVLIVSNNKLGALPPDIGTLGSLRQLDVSSNELQSLPSELCGLSSLRDLNVRRNQLSTL 94
Query: 589 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
P+ L L LD + N++ +P + +L L + + N + PA +
Sbjct: 95 ----------PEELGDLPLVRLDFSCNRVSRIPVSFCRLRHLQVILLDSNPLQSPPAQVC 144
Query: 415 RISTLRYFTISSNE 374
L F S E
Sbjct: 145 LKGKLHIFKYLSTE 158
>AK074723-1|BAC11161.1| 546|Homo sapiens protein ( Homo sapiens
cDNA FLJ90242 fis, clone NT2RM2001626, highly similar to
Leucine-rich repeat-containing protein 8 precursor. ).
Length = 546
Score = 55.6 bits (128), Expect = 2e-07
Identities = 36/125 (28%), Positives = 64/125 (51%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L +L L L+ N+IEK+P + L L L++N L +G + + L+ L
Sbjct: 397 LTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPAD-----IG--LLQNLQNL 449
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
+T+N++ LP +++ KL L +N++ LP+ +G ++ L + N L+ LP L
Sbjct: 450 AITANRIETLPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLPVEL 509
Query: 349 MQCRL 335
+C L
Sbjct: 510 GECPL 514
Score = 49.6 bits (113), Expect = 1e-05
Identities = 40/152 (26%), Positives = 74/152 (48%), Gaps = 19/152 (12%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG-VRGVVDWRWL----------- 566
+ +L L+L ++E++P + NL E+ L +N L + ++ ++ L
Sbjct: 326 MANLTELELIRCDLERIPHSIFSLHNLQEIDLKDNNLKTIEEIISFQHLHRLTCLKLWYN 385
Query: 565 ----LGPQITK--TLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ QI L+ L L NK+ +P ++ KL L + N ++ LPA IG +
Sbjct: 386 HIAYIPIQIGNLTNLERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQN 445
Query: 403 LRYFTISSNELQSLPCSLMQCR-LEYIDISSN 311
L+ I++N +++LP L QCR L + + +N
Sbjct: 446 LQNLAITANRIETLPPELFQCRKLRALHLGNN 477
Score = 48.8 bits (111), Expect = 2e-05
Identities = 34/126 (26%), Positives = 58/126 (46%), Gaps = 2/126 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ LYL+ K+ + + L LDLS+N + LP + G + NL L + N++
Sbjct: 400 LERLYLNRNKIEKIPTQLFYCRKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIET- 458
Query: 589 GVVDWRWLLGPQI--TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
L P++ + L+ L L +N L LP + +L L ++ N + LP +G
Sbjct: 459 --------LPPELFQCRKLRALHLGNNVLRSLPSRVGELTNLTQIELRGNRLECLPVELG 510
Query: 415 RISTLR 398
L+
Sbjct: 511 ECPLLK 516
Score = 41.1 bits (92), Expect = 0.004
Identities = 26/59 (44%), Positives = 32/59 (54%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ L LS L DI LL++L L ++ N IE LPPE + L LHL NN L
Sbjct: 421 RKLRYLDLSHNNLTFLPADIGLLQNLQNLAITANRIETLPPELFQCRKLRALHLGNNVL 479
>BC113973-1|AAI13974.1| 803|Homo sapiens factor for adipocyte
differentiation 158 protein.
Length = 803
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/139 (26%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GVRGVVDWRWLLGPQITKTLKL 533
+ +L L+L + ++E++P + +L EL L N L + +V ++ L + L +
Sbjct: 588 MTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHL------RKLTV 641
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L L N + ++P+ I KL L L + N I LP+ + + +RY +S N+++ +P
Sbjct: 642 LKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPE 701
Query: 352 L-MQCRLEYIDISSNKFDN 299
+ + L+Y I+ NK ++
Sbjct: 702 IGVLQSLQYFSITCNKVES 720
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/126 (30%), Positives = 57/126 (45%), Gaps = 2/126 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI--TKTLK 536
L L L S+N+IE LP + L L+ N + + P+I ++L+
Sbjct: 659 LTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIR---------FIPPEIGVLQSLQ 709
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
+T NK+ LP ++ +KL TLK N +S L IG + L Y + N + LP
Sbjct: 710 YFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPP 769
Query: 355 SLMQCR 338
L CR
Sbjct: 770 ELGDCR 775
Score = 37.5 bits (83), Expect = 0.054
Identities = 35/125 (28%), Positives = 51/125 (40%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 593
+L+ L S K+ + L + LDLS N+I +PPE G + +L + N+ V
Sbjct: 661 SLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNK--V 718
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+ D + K LK L + N L L I L L L N LP +G
Sbjct: 719 ESLPDELY-----FCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPELGD 773
Query: 412 ISTLR 398
L+
Sbjct: 774 CRALK 778
>AB081509-1|BAB86303.1| 803|Homo sapiens AD158 protein.
Length = 803
Score = 54.8 bits (126), Expect = 3e-07
Identities = 37/139 (26%), Positives = 73/139 (52%), Gaps = 2/139 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL-GVRGVVDWRWLLGPQITKTLKL 533
+ +L L+L + ++E++P + +L EL L N L + +V ++ L + L +
Sbjct: 588 MTNLTELELVHCDLERIPHAVFSLLSLQELDLKENNLKSIEEIVSFQHL------RKLTV 641
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L L N + ++P+ I KL L L + N I LP+ + + +RY +S N+++ +P
Sbjct: 642 LKLWHNSITYIPEHIKKLTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPE 701
Query: 352 L-MQCRLEYIDISSNKFDN 299
+ + L+Y I+ NK ++
Sbjct: 702 IGVLQSLQYFSITCNKVES 720
Score = 51.6 bits (118), Expect = 3e-06
Identities = 38/126 (30%), Positives = 57/126 (45%), Gaps = 2/126 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI--TKTLK 536
L L L S+N+IE LP + L L+ N + + P+I ++L+
Sbjct: 659 LTSLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIR---------FIPPEIGVLQSLQ 709
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
+T NK+ LP ++ +KL TLK N +S L IG + L Y + N + LP
Sbjct: 710 YFSITCNKVESLPDELYFCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPP 769
Query: 355 SLMQCR 338
L CR
Sbjct: 770 ELGDCR 775
Score = 37.5 bits (83), Expect = 0.054
Identities = 35/125 (28%), Positives = 51/125 (40%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 593
+L+ L S K+ + L + LDLS N+I +PPE G + +L + N+ V
Sbjct: 661 SLERLSFSHNKIEVLPSHLFLCNKIRYLDLSYNDIRFIPPEIGVLQSLQYFSITCNK--V 718
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+ D + K LK L + N L L I L L L N LP +G
Sbjct: 719 ESLPDELY-----FCKKLKTLKIGKNSLSVLSPKIGNLLFLSYLDVKGNHFEILPPELGD 773
Query: 412 ISTLR 398
L+
Sbjct: 774 CRALK 778
>BC117180-1|AAI17181.1| 2527|Homo sapiens leucine-rich repeat kinase 2
protein.
Length = 2527
Score = 54.4 bits (125), Expect = 4e-07
Identities = 40/128 (31%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLP-PEFGRMANLSELHLANNQ 602
P ++ L LS K IL L HL LD+S+N+I+ LP P + NL EL ++NQ
Sbjct: 1172 PPSMTILKLSQNKFSCIPEAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQ 1231
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM-ISRLPA 425
+ + + + +L ++ L L+ NKL +P I LE L +L + N+ + P
Sbjct: 1232 ISILDLSEKAYL-----WSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELRSFPN 1286
Query: 424 TIGRISTL 401
+G++S +
Sbjct: 1287 EMGKLSKI 1294
Score = 38.3 bits (85), Expect = 0.031
Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 6/139 (4%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSEL-HLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
+++ LDLS NE+ + + L HL +L + + L + K+L L
Sbjct: 982 EYITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL-KSLTHL 1040
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISR---LPATIGRISTLRYFTISSNELQSLP 359
DL SNK P + K+ + L + N I L T+ + TL+ F +S N+L +P
Sbjct: 1041 DLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTV-KCPTLKQFNLSYNQLSFVP 1099
Query: 358 CSLMQC--RLEYIDISSNK 308
+L +LE + + NK
Sbjct: 1100 ENLTDVVEKLEQLILEGNK 1118
>BC031301-1|AAH31301.1| 583|Homo sapiens leucine rich repeat
containing 47 protein.
Length = 583
Score = 54.4 bits (125), Expect = 4e-07
Identities = 47/150 (31%), Positives = 73/150 (48%), Gaps = 11/150 (7%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFG-------RMANLSELHLANNQLGVRGVVDWRWLLGPQI 551
L L VLDLS N +E LPP G + L L+L+ N+L R + P+
Sbjct: 98 LPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRL--RELPADLARCAPR- 154
Query: 550 TKTLKLLDLTSNKLGHLPKAIWK---LEKLVTLKANDNMISRLPATIGRISTLRYFTISS 380
L+ L+LT N L P +++ L L L A DN + L I +++L+ +S+
Sbjct: 155 ---LQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSN 211
Query: 379 NELQSLPCSLMQC-RLEYIDISSNKFDNKQ 293
N+L +P L C +L+ I+ NK +K+
Sbjct: 212 NQLSEIPAELADCPKLKEINFRGNKLRDKR 241
Score = 35.1 bits (77), Expect = 0.29
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
DI L L LDLSNN++ ++P E L E++ N+L
Sbjct: 197 DIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKL 237
>AY792511-1|AAV63975.1| 2527|Homo sapiens leucine-rich repeat kinase 2
protein.
Length = 2527
Score = 54.4 bits (125), Expect = 4e-07
Identities = 40/128 (31%), Positives = 66/128 (51%), Gaps = 2/128 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLP-PEFGRMANLSELHLANNQ 602
P ++ L LS K IL L HL LD+S+N+I+ LP P + NL EL ++NQ
Sbjct: 1172 PPSMTILKLSQNKFSCIPEAILNLPHLRSLDMSSNDIQYLPGPAHWKSLNLRELLFSHNQ 1231
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNM-ISRLPA 425
+ + + + +L ++ L L+ NKL +P I LE L +L + N+ + P
Sbjct: 1232 ISILDLSEKAYL-----WSRVEKLHLSHNKLKEIPPEIGCLENLTSLDVSYNLELRSFPN 1286
Query: 424 TIGRISTL 401
+G++S +
Sbjct: 1287 EMGKLSKI 1294
Score = 38.3 bits (85), Expect = 0.031
Identities = 38/139 (27%), Positives = 63/139 (45%), Gaps = 6/139 (4%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSEL-HLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
+++ LDLS NE+ + + L HL +L + + L + K+L L
Sbjct: 982 EYITSLDLSANELRDIDALSQKCCISVHLEHLEKLELHQNALTSFPQQLCETL-KSLTHL 1040
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISR---LPATIGRISTLRYFTISSNELQSLP 359
DL SNK P + K+ + L + N I L T+ + TL+ F +S N+L +P
Sbjct: 1041 DLHSNKFTSFPSYLLKMSCIANLDVSRNDIGPSVVLDPTV-KCPTLKQFNLSYNQLSFVP 1099
Query: 358 CSLMQC--RLEYIDISSNK 308
+L +LE + + NK
Sbjct: 1100 ENLTDVVEKLEQLILEGNK 1118
>AY358112-1|AAQ88479.1| 802|Homo sapiens ITLT6413 protein.
Length = 802
Score = 54.4 bits (125), Expect = 4e-07
Identities = 45/159 (28%), Positives = 74/159 (46%), Gaps = 2/159 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGV 593
L+SL L L I L +L LDL N ++ + F + NLS L L +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEISFQHLQNLSCLKLWHNNIAY 646
Query: 592 RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGR 413
+G L+ L L N + +LP ++ KL L + N ++ +P I
Sbjct: 647 IPAQ-----IGA--LSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQY 699
Query: 412 ISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+S L+YF +++N ++ LP L QC +L+ + + N N
Sbjct: 700 LSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMN 738
>AL365330-3|CAI42528.1| 583|Homo sapiens leucine rich repeat
containing 47 protein.
Length = 583
Score = 54.4 bits (125), Expect = 4e-07
Identities = 47/150 (31%), Positives = 73/150 (48%), Gaps = 11/150 (7%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFG-------RMANLSELHLANNQLGVRGVVDWRWLLGPQI 551
L L VLDLS N +E LPP G + L L+L+ N+L R + P+
Sbjct: 98 LPALRVLDLSGNALEALPPGQGLGPAEPPGLPQLQSLNLSGNRL--RELPADLARCAPR- 154
Query: 550 TKTLKLLDLTSNKLGHLPKAIWK---LEKLVTLKANDNMISRLPATIGRISTLRYFTISS 380
L+ L+LT N L P +++ L L L A DN + L I +++L+ +S+
Sbjct: 155 ---LQSLNLTGNCLDSFPAELFRPGALPLLSELAAADNCLRELSPDIAHLASLKTLDLSN 211
Query: 379 NELQSLPCSLMQC-RLEYIDISSNKFDNKQ 293
N+L +P L C +L+ I+ NK +K+
Sbjct: 212 NQLSEIPAELADCPKLKEINFRGNKLRDKR 241
Score = 35.1 bits (77), Expect = 0.29
Identities = 16/41 (39%), Positives = 23/41 (56%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
DI L L LDLSNN++ ++P E L E++ N+L
Sbjct: 197 DIAHLASLKTLDLSNNQLSEIPAELADCPKLKEINFRGNKL 237
>D86984-1|BAA13220.2| 823|Homo sapiens KIAA0231 protein protein.
Length = 823
Score = 53.6 bits (123), Expect = 8e-07
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 3/160 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 596
L+SL L L I L +L LDL N ++ + F + NLS L L +N +
Sbjct: 607 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 666
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+G L+ L L N + +LP ++ KL L + N ++ +P I
Sbjct: 667 YIPAQ-----IGA--LSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQ 719
Query: 415 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+S L+YF +++N ++ LP L QC +L+ + + N N
Sbjct: 720 YLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMN 759
>BC108252-1|AAI08253.1| 532|Homo sapiens LRRC8E protein protein.
Length = 532
Score = 53.6 bits (123), Expect = 8e-07
Identities = 43/145 (29%), Positives = 70/145 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L +L L ++ + L+ L L LS N++E LP + G + L L +++N G
Sbjct: 366 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHN--G 423
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + LL + L+ L L+ N L LP+ ++ KL TL DN +S+L +G
Sbjct: 424 LHSLPPEVGLL-----QNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVG 478
Query: 415 RISTLRYFTISSNELQSLPCSLMQC 341
+ L + N L++LP L C
Sbjct: 479 ALRALSRLELKGNRLEALPEELGNC 503
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 584
SL+ G +L + L L L+L +E++P + L EL L +N L R +
Sbjct: 300 SLHNDGARLVALN-SLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHL--RSI 356
Query: 583 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ +L Q + L L L N++ ++P+ + KL L L + N + LP+ +G S
Sbjct: 357 EE---ILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSG 413
Query: 403 LRYFTISSNELQSLP--CSLMQCRLEYIDISSNKFD 302
LR +S N L SLP L+Q L+++ +S N +
Sbjct: 414 LRLLDVSHNGLHSLPPEVGLLQ-NLQHLALSYNALE 448
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/126 (30%), Positives = 59/126 (46%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ LYLS KL + L L +LD+S+N + LPPE G + NL L L+ N L
Sbjct: 389 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNAL- 447
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + + L+ L L N+L L + L L L+ N + LP +G
Sbjct: 448 -EALPEELF-----FCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 501
Query: 415 RISTLR 398
L+
Sbjct: 502 NCGGLK 507
Score = 42.7 bits (96), Expect = 0.001
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 2/146 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 596
L+ L L L + L L LDL +N + + F L L L +NQ+
Sbjct: 320 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 379
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
V + L ++L+ L L+ NKL LP + L L + N + LP +G
Sbjct: 380 Y--VPEHVRKL-----RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVG 432
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR 338
+ L++ +S N L++LP L CR
Sbjct: 433 LLQNLQHLALSYNALEALPEELFFCR 458
>BC070089-1|AAH70089.1| 796|Homo sapiens leucine rich repeat
containing 8 family, member E protein.
Length = 796
Score = 53.6 bits (123), Expect = 8e-07
Identities = 43/145 (29%), Positives = 70/145 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L +L L ++ + L+ L L LS N++E LP + G + L L +++N G
Sbjct: 630 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHN--G 687
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + LL + L+ L L+ N L LP+ ++ KL TL DN +S+L +G
Sbjct: 688 LHSLPPEVGLL-----QNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVG 742
Query: 415 RISTLRYFTISSNELQSLPCSLMQC 341
+ L + N L++LP L C
Sbjct: 743 ALRALSRLELKGNRLEALPEELGNC 767
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 584
SL+ G +L + L L L+L +E++P + L EL L +N L R +
Sbjct: 564 SLHNDGARLVALN-SLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHL--RSI 620
Query: 583 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ +L Q + L L L N++ ++P+ + KL L L + N + LP+ +G S
Sbjct: 621 EE---ILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSG 677
Query: 403 LRYFTISSNELQSLP--CSLMQCRLEYIDISSNKFD 302
LR +S N L SLP L+Q L+++ +S N +
Sbjct: 678 LRLLDVSHNGLHSLPPEVGLLQ-NLQHLALSYNALE 712
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/126 (30%), Positives = 59/126 (46%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ LYLS KL + L L +LD+S+N + LPPE G + NL L L+ N L
Sbjct: 653 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNAL- 711
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + + L+ L L N+L L + L L L+ N + LP +G
Sbjct: 712 -EALPEELF-----FCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 765
Query: 415 RISTLR 398
L+
Sbjct: 766 NCGGLK 771
Score = 42.7 bits (96), Expect = 0.001
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 2/146 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 596
L+ L L L + L L LDL +N + + F L L L +NQ+
Sbjct: 584 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 643
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
V + L ++L+ L L+ NKL LP + L L + N + LP +G
Sbjct: 644 Y--VPEHVRKL-----RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVG 696
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR 338
+ L++ +S N L++LP L CR
Sbjct: 697 LLQNLQHLALSYNALEALPEELFFCR 722
>BC060782-1|AAH60782.1| 803|Homo sapiens LRRC8B protein protein.
Length = 803
Score = 53.6 bits (123), Expect = 8e-07
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 3/160 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 596
L+SL L L I L +L LDL N ++ + F + NLS L L +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 646
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+G L+ L L N + +LP ++ KL L + N ++ +P I
Sbjct: 647 YIPAQ-----IGA--LSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQ 699
Query: 415 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+S L+YF +++N ++ LP L QC +L+ + + N N
Sbjct: 700 YLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMN 739
>BC036722-1|AAH36722.1| 261|Homo sapiens leucine rich repeat
containing 18 protein.
Length = 261
Score = 53.6 bits (123), Expect = 8e-07
Identities = 32/111 (28%), Positives = 63/111 (56%), Gaps = 1/111 (0%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLKLL 530
++L LDL +N I+KLP G+M +L L+++NN+L G+ V+ + L K ++ +
Sbjct: 73 QNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLPVELKQL------KNIRAV 126
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 377
+L N L + + L++L + +DN+++ +P +I ++ L+ I N
Sbjct: 127 NLGLNHLDSVSTTLGALKELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRN 177
Score = 49.6 bits (113), Expect = 1e-05
Identities = 27/81 (33%), Positives = 47/81 (58%), Gaps = 3/81 (3%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS--LP 359
LDL+ N + +P +I K + L L + N I +LP +IG++++L Y +S+N L S LP
Sbjct: 55 LDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLPESIGQMTSLLYLNVSNNRLTSNGLP 114
Query: 358 CSLMQCR-LEYIDISSNKFDN 299
L Q + + +++ N D+
Sbjct: 115 VELKQLKNIRAVNLGLNHLDS 135
Score = 47.6 bits (108), Expect = 5e-05
Identities = 42/155 (27%), Positives = 76/155 (49%), Gaps = 3/155 (1%)
Frame = -2
Query: 760 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 581
L LS + + F + IL L + LDLS N I K+P + NL L L +N +
Sbjct: 32 LDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYID----- 86
Query: 580 DWRWLLGPQITKTLKLLDLTSNKL--GHLPKAIWKLEKLVTLKANDNMISRLPATIGRIS 407
+G Q+T +L L++++N+L LP + +L+ + + N + + T+G +
Sbjct: 87 KLPESIG-QMT-SLLYLNVSNNRLTSNGLPVELKQLKNIRAVNLGLNHLDSVSTTLGALK 144
Query: 406 TLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKF 305
L + N L ++P S+ + +L+ ++I N F
Sbjct: 145 ELHEVGLHDNLLNNIPVSISKLPKLKKLNIKRNPF 179
Score = 47.2 bits (107), Expect = 7e-05
Identities = 25/78 (32%), Positives = 44/78 (56%), Gaps = 1/78 (1%)
Frame = -2
Query: 538 KLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLP 359
K LDL+ + PK I +L + L + N+I ++P +I + LR+ + SN + LP
Sbjct: 30 KRLDLSKMGITTFPKCILRLSDMDELDLSRNLIRKIPDSISKFQNLRWLDLHSNYIDKLP 89
Query: 358 CSLMQ-CRLEYIDISSNK 308
S+ Q L Y+++S+N+
Sbjct: 90 ESIGQMTSLLYLNVSNNR 107
>BC030607-1|AAH30607.1| 803|Homo sapiens leucine rich repeat
containing 8 family, member B protein.
Length = 803
Score = 53.6 bits (123), Expect = 8e-07
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 3/160 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 596
L+SL L L I L +L LDL N ++ + F + NLS L L +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 646
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+G L+ L L N + +LP ++ KL L + N ++ +P I
Sbjct: 647 YIPAQ-----IGA--LSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQ 699
Query: 415 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+S L+YF +++N ++ LP L QC +L+ + + N N
Sbjct: 700 YLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMN 739
>BC022216-1|AAH22216.2| 592|Homo sapiens LRRC8E protein protein.
Length = 592
Score = 53.6 bits (123), Expect = 8e-07
Identities = 43/145 (29%), Positives = 70/145 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L +L L ++ + L+ L L LS N++E LP + G + L L +++N G
Sbjct: 426 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHN--G 483
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + LL + L+ L L+ N L LP+ ++ KL TL DN +S+L +G
Sbjct: 484 LHSLPPEVGLL-----QNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVG 538
Query: 415 RISTLRYFTISSNELQSLPCSLMQC 341
+ L + N L++LP L C
Sbjct: 539 ALRALSRLELKGNRLEALPEELGNC 563
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 584
SL+ G +L + L L L+L +E++P + L EL L +N L R +
Sbjct: 360 SLHNDGARLVALN-SLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHL--RSI 416
Query: 583 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ +L Q + L L L N++ ++P+ + KL L L + N + LP+ +G S
Sbjct: 417 EE---ILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSG 473
Query: 403 LRYFTISSNELQSLP--CSLMQCRLEYIDISSNKFD 302
LR +S N L SLP L+Q L+++ +S N +
Sbjct: 474 LRLLDVSHNGLHSLPPEVGLLQ-NLQHLALSYNALE 508
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/126 (30%), Positives = 59/126 (46%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ LYLS KL + L L +LD+S+N + LPPE G + NL L L+ N L
Sbjct: 449 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNAL- 507
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + + L+ L L N+L L + L L L+ N + LP +G
Sbjct: 508 -EALPEELF-----FCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 561
Query: 415 RISTLR 398
L+
Sbjct: 562 NCGGLK 567
Score = 42.7 bits (96), Expect = 0.001
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 2/146 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 596
L+ L L L + L L LDL +N + + F L L L +NQ+
Sbjct: 380 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 439
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
V + L ++L+ L L+ NKL LP + L L + N + LP +G
Sbjct: 440 Y--VPEHVRKL-----RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVG 492
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR 338
+ L++ +S N L++LP L CR
Sbjct: 493 LLQNLQHLALSYNALEALPEELFFCR 518
>AL834474-1|CAD39133.1| 622|Homo sapiens hypothetical protein
protein.
Length = 622
Score = 53.6 bits (123), Expect = 8e-07
Identities = 43/145 (29%), Positives = 70/145 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L +L L ++ + L+ L L LS N++E LP + G + L L +++N G
Sbjct: 456 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHN--G 513
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + LL + L+ L L+ N L LP+ ++ KL TL DN +S+L +G
Sbjct: 514 LHSLPPEVGLL-----QNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVG 568
Query: 415 RISTLRYFTISSNELQSLPCSLMQC 341
+ L + N L++LP L C
Sbjct: 569 ALRALSRLELKGNRLEALPEELGNC 593
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 584
SL+ G +L + L L L+L +E++P + L EL L +N L R +
Sbjct: 390 SLHNDGARLVALN-SLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHL--RSI 446
Query: 583 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ +L Q + L L L N++ ++P+ + KL L L + N + LP+ +G S
Sbjct: 447 EE---ILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSG 503
Query: 403 LRYFTISSNELQSLP--CSLMQCRLEYIDISSNKFD 302
LR +S N L SLP L+Q L+++ +S N +
Sbjct: 504 LRLLDVSHNGLHSLPPEVGLLQ-NLQHLALSYNALE 538
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/126 (30%), Positives = 59/126 (46%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ LYLS KL + L L +LD+S+N + LPPE G + NL L L+ N L
Sbjct: 479 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNAL- 537
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + + L+ L L N+L L + L L L+ N + LP +G
Sbjct: 538 -EALPEELF-----FCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 591
Query: 415 RISTLR 398
L+
Sbjct: 592 NCGGLK 597
Score = 42.7 bits (96), Expect = 0.001
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 2/146 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 596
L+ L L L + L L LDL +N + + F L L L +NQ+
Sbjct: 410 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 469
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
V + L ++L+ L L+ NKL LP + L L + N + LP +G
Sbjct: 470 Y--VPEHVRKL-----RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVG 522
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR 338
+ L++ +S N L++LP L CR
Sbjct: 523 LLQNLQHLALSYNALEALPEELFFCR 548
>AK027073-1|BAB15648.1| 444|Homo sapiens protein ( Homo sapiens
cDNA: FLJ23420 fis, clone HEP22352. ).
Length = 444
Score = 53.6 bits (123), Expect = 8e-07
Identities = 43/145 (29%), Positives = 70/145 (48%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R L +L L ++ + L+ L L LS N++E LP + G + L L +++N G
Sbjct: 278 RKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHN--G 335
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + LL + L+ L L+ N L LP+ ++ KL TL DN +S+L +G
Sbjct: 336 LHSLPPEVGLL-----QNLQHLALSYNALEALPEELFFCRKLRTLLLGDNQLSQLSPHVG 390
Query: 415 RISTLRYFTISSNELQSLPCSLMQC 341
+ L + N L++LP L C
Sbjct: 391 ALRALSRLELKGNRLEALPEELGNC 415
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/156 (29%), Positives = 76/156 (48%), Gaps = 2/156 (1%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGV 584
SL+ G +L + L L L+L +E++P + L EL L +N L R +
Sbjct: 212 SLHNDGARLVALN-SLKKLAALRELELVACGLERIPHAVFSLGALQELDLKDNHL--RSI 268
Query: 583 VDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRIST 404
+ +L Q + L L L N++ ++P+ + KL L L + N + LP+ +G S
Sbjct: 269 EE---ILSFQHCRKLVTLRLWHNQIAYVPEHVRKLRSLEQLYLSYNKLETLPSQLGLCSG 325
Query: 403 LRYFTISSNELQSLP--CSLMQCRLEYIDISSNKFD 302
LR +S N L SLP L+Q L+++ +S N +
Sbjct: 326 LRLLDVSHNGLHSLPPEVGLLQ-NLQHLALSYNALE 360
Score = 52.0 bits (119), Expect = 2e-06
Identities = 39/126 (30%), Positives = 59/126 (46%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
R+L+ LYLS KL + L L +LD+S+N + LPPE G + NL L L+ N L
Sbjct: 301 RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVGLLQNLQHLALSYNAL- 359
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+ + + + L+ L L N+L L + L L L+ N + LP +G
Sbjct: 360 -EALPEELF-----FCRKLRTLLLGDNQLSQLSPHVGALRALSRLELKGNRLEALPEELG 413
Query: 415 RISTLR 398
L+
Sbjct: 414 NCGGLK 419
Score = 42.7 bits (96), Expect = 0.001
Identities = 41/146 (28%), Positives = 63/146 (43%), Gaps = 2/146 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 596
L+ L L L + L L LDL +N + + F L L L +NQ+
Sbjct: 232 LRELELVACGLERIPHAVFSLGALQELDLKDNHLRSIEEILSFQHCRKLVTLRLWHNQIA 291
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
V + L ++L+ L L+ NKL LP + L L + N + LP +G
Sbjct: 292 Y--VPEHVRKL-----RSLEQLYLSYNKLETLPSQLGLCSGLRLLDVSHNGLHSLPPEVG 344
Query: 415 RISTLRYFTISSNELQSLPCSLMQCR 338
+ L++ +S N L++LP L CR
Sbjct: 345 LLQNLQHLALSYNALEALPEELFFCR 370
>AK000338-1|BAA91094.1| 384|Homo sapiens protein ( Homo sapiens
cDNA FLJ20331 fis, clone HEP10410. ).
Length = 384
Score = 53.6 bits (123), Expect = 8e-07
Identities = 39/134 (29%), Positives = 65/134 (48%), Gaps = 1/134 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
+K L LD ++N +E +PPE M +L L+L N+L R+L LK L
Sbjct: 1 MKRLKHLDCNSNLLETIPPELAGMESLELLYLRRNKL--------RFLPEFPSCSLLKEL 52
Query: 529 DLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
+ N++ L K L ++ L DN + +P I + +L +S+N++ SLP S
Sbjct: 53 HVGENQIEMLEAEHLKHLNSILVLDLRDNKLKSVPDEIILLRSLERLDLSNNDISSLPYS 112
Query: 352 LMQCRLEYIDISSN 311
L L+++ + N
Sbjct: 113 LGNLHLKFLALEGN 126
Score = 42.3 bits (95), Expect = 0.002
Identities = 26/83 (31%), Positives = 43/83 (51%), Gaps = 2/83 (2%)
Frame = -2
Query: 553 ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNE 374
+ + L LDL +N L LP+ + L +L T+ + N LP + RI TL IS+N+
Sbjct: 252 VLQKLTFLDLRNNFLNSLPEEMESLVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQ 311
Query: 373 LQSLPCSLMQC--RLEYIDISSN 311
+ S+ M+ L +D+ +N
Sbjct: 312 VGSVDPQKMKMMENLTTLDLQNN 334
Score = 37.5 bits (83), Expect = 0.054
Identities = 19/61 (31%), Positives = 36/61 (59%), Gaps = 1/61 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFR-RDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
TL+++ +S ++ + + + ++++L LDL NN++ ++PPE G NL L L N
Sbjct: 301 TLETILISNNQVGSVDPQKMKMMENLTTLDLQNNDLLQIPPELGNCVNLRTLLLDGNPFR 360
Query: 595 V 593
V
Sbjct: 361 V 361
Score = 34.7 bits (76), Expect = 0.38
Identities = 21/48 (43%), Positives = 28/48 (58%)
Frame = -2
Query: 742 KLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
KL + +I+LL+ L LDLSNN+I LP G + +L L L N L
Sbjct: 82 KLKSVPDEIILLRSLERLDLSNNDISSLPYSLGNL-HLKFLALEGNPL 128
Score = 32.7 bits (71), Expect = 1.5
Identities = 26/88 (29%), Positives = 43/88 (48%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L ++LS N + LP R+ L + ++NNQ+ G VD + + ++ + L L
Sbjct: 276 LVRLQTINLSFNRFKMLPEVLYRIFTLETILISNNQV---GSVDPQKM---KMMENLTTL 329
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDN 446
DL +N L +P + L TL + N
Sbjct: 330 DLQNNDLLQIPPELGNCVNLRTLLLDGN 357
>AF385436-1|AAM43837.1| 803|Homo sapiens T-cell activation leucine
repeat-rich protein protein.
Length = 803
Score = 53.6 bits (123), Expect = 8e-07
Identities = 45/160 (28%), Positives = 74/160 (46%), Gaps = 3/160 (1%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP--EFGRMANLSELHLANNQLG 596
L+SL L L I L +L LDL N ++ + F + NLS L L +N +
Sbjct: 587 LKSLELISCDLERIPHSIFSLNNLHELDLRENNLKTVEEIISFQHLQNLSCLKLWHNNIA 646
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
+G L+ L L N + +LP ++ KL L + N ++ +P I
Sbjct: 647 YIPAQ-----IGA--LSNLEQLSLDHNNIENLPLQLFLCTKLHYLDLSYNHLTFIPEEIQ 699
Query: 415 RISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNKFDN 299
+S L+YF +++N ++ LP L QC +L+ + + N N
Sbjct: 700 YLSNLQYFAVTNNNIEMLPDGLFQCKKLQCLLLGKNSLMN 739
>AB033020-1|BAA86508.1| 575|Homo sapiens KIAA1194 protein protein.
Length = 575
Score = 53.6 bits (123), Expect = 8e-07
Identities = 29/59 (49%), Positives = 35/59 (59%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV 593
L +L+LS L DI L +L LDLS+N+I LP E G M +L ELHL NN L V
Sbjct: 71 LTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAELGNMVSLRELHLNNNLLRV 129
Score = 50.8 bits (116), Expect = 5e-06
Identities = 22/57 (38%), Positives = 35/57 (61%)
Frame = -2
Query: 520 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
S K+ L ++W L L L +DN +SR+P+ I ++ L Y +SSN+++SLP L
Sbjct: 55 SGKVRSLSASLWSLTHLTALHLSDNSLSRIPSDIAKLHNLVYLDLSSNKIRSLPAEL 111
Score = 43.2 bits (97), Expect = 0.001
Identities = 33/111 (29%), Positives = 54/111 (48%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 524
H A L++S ++ L + +L+ LHL++N L R D L L LDL
Sbjct: 48 HWAELEISG-KVRSLSASLWSLTHLTALHLSDNSLS-RIPSDIAKL------HNLVYLDL 99
Query: 523 TSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
+SNK+ LP + + L L N+N++ LP +G++ L+ + N L
Sbjct: 100 SSNKIRSLPAELGNMVSLRELHLNNNLLRVLPFELGKLFQLQTLGLKGNPL 150
>BC007504-1|AAH07504.1| 712|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 3 protein.
Length = 712
Score = 53.2 bits (122), Expect = 1e-06
Identities = 50/168 (29%), Positives = 74/168 (44%), Gaps = 17/168 (10%)
Frame = -2
Query: 760 LYLSGLKLCNFRRDILL--LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGV-- 593
L LSG KL F R L DLS N + ++P E +L L+L N +
Sbjct: 62 LSLSGRKLREFPRGAANHDLTDTTRADLSRNRLSEIPIEACHFVSLENLNLYQNCIRYIP 121
Query: 592 RGVVDWRWLLGPQITKT-------------LKLLDLTSNKLGHLPKAIWKLEKLVTLKAN 452
+++ + L I++ LK+L ++NKL LP+ I L L+ L +
Sbjct: 122 EAILNLQALTFLNISRNQLSTLPVHLCNLPLKVLIASNNKLVSLPEEIGHLRHLMELDVS 181
Query: 451 DNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQCRLEYIDISSNK 308
N I +P+ IG + LR + N L LP L + L +D S NK
Sbjct: 182 CNEIQTIPSQIGNLEALRDLNVRRNHLVHLPEELAELPLIRLDFSCNK 229
Score = 48.4 bits (110), Expect = 3e-05
Identities = 39/135 (28%), Positives = 64/135 (47%), Gaps = 5/135 (3%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ L S KL + +I L+HL LD+S NEI+ +P + G + L +L++ N L
Sbjct: 152 LKVLIASNNKLVSLPEEIGHLRHLMELDVSCNEIQTIPSQIGNLEALRDLNVRRNHL--- 208
Query: 589 GVVDWRWLLGPQITKTLKL--LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI- 419
+ P+ L L LD + NK+ +P L L T+ ++N + PA I
Sbjct: 209 -------VHLPEELAELPLIRLDFSCNKITTIPVCYRNLRHLQTITLDNNPLQSPPAQIC 261
Query: 418 --GRISTLRYFTISS 380
G++ +Y I +
Sbjct: 262 IKGKVHIFKYLNIQA 276
>AL356953-1|CAI15927.1| 967|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 967
Score = 52.8 bits (121), Expect = 1e-06
Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 3/116 (2%)
Frame = -2
Query: 697 AVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 521
A LDLS N + +L P F + L EL L+ N L + + G +LK+L L
Sbjct: 69 AYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILMLQ 122
Query: 520 SNKLGHLP-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 359
+N+LG +P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 123 NNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 178
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 351 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 403
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 398
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 404 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 449
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L + L+ N I +P F + +L LHL NN++ G + L L+
Sbjct: 185 LPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL------HNLET 238
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 428
LDL NKL P AI L +L L ++N I +P
Sbjct: 239 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 273
>AB049405-1|BAB39854.1| 928|Homo sapiens VTS20631 protein.
Length = 928
Score = 52.8 bits (121), Expect = 1e-06
Identities = 39/116 (33%), Positives = 64/116 (55%), Gaps = 3/116 (2%)
Frame = -2
Query: 697 AVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLT 521
A LDLS N + +L P F + L EL L+ N L + + G +LK+L L
Sbjct: 30 AYLDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILMLQ 83
Query: 520 SNKLGHLP-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 359
+N+LG +P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 84 NNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 139
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 312 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 364
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 398
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 365 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 410
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L + L+ N I +P F + +L LHL NN++ G + L L+
Sbjct: 146 LPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL------HNLET 199
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 428
LDL NKL P AI L +L L ++N I +P
Sbjct: 200 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 234
>BC125224-1|AAI25225.1| 748|Homo sapiens LRCH2 protein protein.
Length = 748
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 3/133 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ L +S KL + +I LK L LD+S NEI+ LP + G++ +L EL++ N L V
Sbjct: 181 LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHV- 239
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI--- 419
+ D LG L LD + NK+ +P KL L + ++N + PA I
Sbjct: 240 -LPD---ELG---DLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLK 292
Query: 418 GRISTLRYFTISS 380
G++ +Y I +
Sbjct: 293 GKVHIFKYLNIQA 305
Score = 50.4 bits (115), Expect = 7e-06
Identities = 42/137 (30%), Positives = 66/137 (48%), Gaps = 3/137 (2%)
Frame = -2
Query: 760 LYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVV 581
L LSG KL +F L DLS N ++P + A L L+L +N +
Sbjct: 93 LSLSGRKLRDFPGSGYDLTDTTQADLSRNRFTEIPSDVWLFAPLETLNLYHNCIKTI--- 149
Query: 580 DWRWLLGPQITKTLKLL---DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRI 410
P+ K L++L +++ N L LPK ++ L V + +N+ ++S +P IG++
Sbjct: 150 -------PEAIKNLQMLTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVS-IPEEIGKL 201
Query: 409 STLRYFTISSNELQSLP 359
L IS NE+Q LP
Sbjct: 202 KDLMELDISCNEIQVLP 218
Score = 50.4 bits (115), Expect = 7e-06
Identities = 28/85 (32%), Positives = 41/85 (48%)
Frame = -2
Query: 562 GPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTIS 383
G +T T + DL+ N+ +P +W L TL N I +P I + L Y IS
Sbjct: 107 GYDLTDTTQA-DLSRNRFTEIPSDVWLFAPLETLNLYHNCIKTIPEAIKNLQMLTYLNIS 165
Query: 382 SNELQSLPCSLMQCRLEYIDISSNK 308
N L +LP L L+ + +S+NK
Sbjct: 166 RNLLSTLPKYLFDLPLKVLVVSNNK 190
>AL589786-1|CAH70721.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 3/133 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ L +S KL + +I LK L LD+S NEI+ LP + G++ +L EL++ N L V
Sbjct: 24 LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHV- 82
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI--- 419
+ D LG L LD + NK+ +P KL L + ++N + PA I
Sbjct: 83 -LPD---ELG---DLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLK 135
Query: 418 GRISTLRYFTISS 380
G++ +Y I +
Sbjct: 136 GKVHIFKYLNIQA 148
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/61 (36%), Positives = 36/61 (59%)
Frame = -2
Query: 541 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L L+++ N L LPK ++ L V + +N+ ++S +P IG++ L IS NE+Q L
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVS-IPEEIGKLKDLMELDISCNEIQVL 60
Query: 361 P 359
P
Sbjct: 61 P 61
>AL445164-1|CAI43033.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 3/133 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ L +S KL + +I LK L LD+S NEI+ LP + G++ +L EL++ N L V
Sbjct: 24 LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHV- 82
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI--- 419
+ D LG L LD + NK+ +P KL L + ++N + PA I
Sbjct: 83 -LPD---ELG---DLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLK 135
Query: 418 GRISTLRYFTISS 380
G++ +Y I +
Sbjct: 136 GKVHIFKYLNIQA 148
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/61 (36%), Positives = 36/61 (59%)
Frame = -2
Query: 541 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L L+++ N L LPK ++ L V + +N+ ++S +P IG++ L IS NE+Q L
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVS-IPEEIGKLKDLMELDISCNEIQVL 60
Query: 361 P 359
P
Sbjct: 61 P 61
>AL121878-2|CAI42077.1| 612|Homo sapiens leucine-rich repeats and
calponin homology (CH) domain containing 2 protein.
Length = 612
Score = 52.0 bits (119), Expect = 2e-06
Identities = 43/133 (32%), Positives = 67/133 (50%), Gaps = 3/133 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVR 590
L+ L +S KL + +I LK L LD+S NEI+ LP + G++ +L EL++ N L V
Sbjct: 24 LKVLVVSNNKLVSIPEEIGKLKDLMELDISCNEIQVLPQQMGKLHSLRELNIRRNNLHV- 82
Query: 589 GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI--- 419
+ D LG L LD + NK+ +P KL L + ++N + PA I
Sbjct: 83 -LPD---ELG---DLPLVKLDFSCNKVTEIPVCYRKLHHLQVIILDNNPLQVPPAQICLK 135
Query: 418 GRISTLRYFTISS 380
G++ +Y I +
Sbjct: 136 GKVHIFKYLNIQA 148
Score = 41.1 bits (92), Expect = 0.004
Identities = 22/61 (36%), Positives = 36/61 (59%)
Frame = -2
Query: 541 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L L+++ N L LPK ++ L V + +N+ ++S +P IG++ L IS NE+Q L
Sbjct: 2 LTYLNISRNLLSTLPKYLFDLPLKVLVVSNNKLVS-IPEEIGKLKDLMELDISCNEIQVL 60
Query: 361 P 359
P
Sbjct: 61 P 61
>AK058188-1|BAB71707.1| 475|Homo sapiens protein ( Homo sapiens
cDNA FLJ25459 fis, clone TST09038. ).
Length = 475
Score = 51.6 bits (118), Expect = 3e-06
Identities = 23/57 (40%), Positives = 34/57 (59%)
Frame = -2
Query: 520 SNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSL 350
S ++ L ++W L L L NDN +SR+P I ++ L Y +SSN+L+SLP L
Sbjct: 42 SGRVRSLSTSLWSLTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKLRSLPAEL 98
Score = 44.0 bits (99), Expect = 6e-04
Identities = 34/110 (30%), Positives = 52/110 (47%), Gaps = 2/110 (1%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITK--TLKLL 530
H A L++S + L + +L+ LHL +N L + P I K L L
Sbjct: 35 HWAELEISGR-VRSLSTSLWSLTHLTALHLNDNYLS---------RIPPDIAKLHNLVYL 84
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 380
DL+SNKL LP + + L L N+N++ LP +GR+ L F + +
Sbjct: 85 DLSSNKLRSLPAELGNMVSLRELLLNNNLLRVLPYELGRLFQLLNFMLDN 134
Score = 35.5 bits (78), Expect = 0.22
Identities = 14/37 (37%), Positives = 25/37 (67%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
L HL L L++N + ++PP+ ++ NL L L++N+L
Sbjct: 55 LTHLTALHLNDNYLSRIPPDIAKLHNLVYLDLSSNKL 91
>BC025681-1|AAH25681.1| 605|Homo sapiens insulin-like growth factor
binding protein, acid labile subunit protein.
Length = 605
Score = 51.2 bits (117), Expect = 4e-06
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 23/156 (14%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG-VR-----GVVDWR------- 572
L ++AV++LS N + LP + F + L LHL + LG +R G+ R
Sbjct: 361 LTNMAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 571 WLLGPQITKTLKL-----LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPA-TIGR 413
L+G + L LDLTSN+L HLP +++ L KL L + N ++ LPA +G
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGP 480
Query: 412 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSN 311
+ + +S N L++LP SL+ RL Y+ + +N
Sbjct: 481 LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
>M86826-1|AAA36047.1| 605|Homo sapiens insulin-like growth factor
binding protein complex protein.
Length = 605
Score = 50.8 bits (116), Expect = 5e-06
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 23/156 (14%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG-VR-----GVVDWR------- 572
L ++AV++LS N + LP + F + L LHL + LG +R G+ R
Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 571 WLLGPQITKTLKL-----LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPA-TIGR 413
L+G + L LDLTSN+L HLP +++ L KL L + N ++ LPA +G
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGP 480
Query: 412 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSN 311
+ + +S N L++LP SL+ RL Y+ + +N
Sbjct: 481 LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
>AL031724-2|CAC36078.1| 605|Homo sapiens C447E6.2 (insulin-like
growth factor binding protein, acid labile subunit)
protein.
Length = 605
Score = 50.8 bits (116), Expect = 5e-06
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 23/156 (14%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG-VR-----GVVDWR------- 572
L ++AV++LS N + LP + F + L LHL + LG +R G+ R
Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 571 WLLGPQITKTLKL-----LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPA-TIGR 413
L+G + L LDLTSN+L HLP +++ L KL L + N ++ LPA +G
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGP 480
Query: 412 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSN 311
+ + +S N L++LP SL+ RL Y+ + +N
Sbjct: 481 LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
>AF192554-1|AAF06774.1| 605|Homo sapiens acid-labile subunit
protein.
Length = 605
Score = 50.8 bits (116), Expect = 5e-06
Identities = 51/156 (32%), Positives = 80/156 (51%), Gaps = 23/156 (14%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG-VR-----GVVDWR------- 572
L ++AV++LS N + LP + F + L LHL + LG +R G+ R
Sbjct: 361 LTNVAVMNLSGNCLRNLPEQVFRGLGKLHSLHLEGSCLGRIRPHTFTGLSGLRRLFLKDN 420
Query: 571 WLLGPQITKTLKL-----LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLPA-TIGR 413
L+G + L LDLTSN+L HLP +++ L KL L + N ++ LPA +G
Sbjct: 421 GLVGIEEQSLWGLAELLELDLTSNQLTHLPHRLFQGLGKLEYLLLSRNRLAELPADALGP 480
Query: 412 ISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSN 311
+ + +S N L++LP SL+ RL Y+ + +N
Sbjct: 481 LQRAFWLDVSHNRLEALPNSLLAPLGRLRYLSLRNN 516
>BC047905-1|AAH47905.2| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 50.4 bits (115), Expect = 7e-06
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 3/117 (2%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 524
++ DLS N + +L P F + L EL L+ N L + + G +LK+L L
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILML 69
Query: 523 TSNKLGHLP-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 359
+N+LG +P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 70 QNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 126
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 299 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 351
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 398
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 352 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 397
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L + L+ N I +P F + +L LHL NN++ G + L L+
Sbjct: 133 LPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL------HNLET 186
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 428
LDL NKL P AI L +L L ++N I +P
Sbjct: 187 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 221
>AY358119-1|AAQ88486.1| 915|Homo sapiens gonadotropin receptor
protein.
Length = 915
Score = 50.4 bits (115), Expect = 7e-06
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 3/117 (2%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 524
++ DLS N + +L P F + L EL L+ N L + + G +LK+L L
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILML 69
Query: 523 TSNKLGHLP-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 359
+N+LG +P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 70 QNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 126
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 299 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 351
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 398
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 352 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 397
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L + L+ N I +P F + +L LHL NN++ G + L L+
Sbjct: 133 LPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL------HNLET 186
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 428
LDL NKL P AI L +L L ++N I +P
Sbjct: 187 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 221
>AL356953-3|CAI15929.1| 915|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 915
Score = 50.4 bits (115), Expect = 7e-06
Identities = 37/117 (31%), Positives = 64/117 (54%), Gaps = 3/117 (2%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 524
++ DLS N + +L P F + L EL L+ N L + + G +LK+L L
Sbjct: 16 ISARDLSMNNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILML 69
Query: 523 TSNKLGHLP-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 359
+N+LG +P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 70 QNNQLGGIPAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 126
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 299 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 351
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 398
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 352 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 397
Score = 38.7 bits (86), Expect = 0.023
Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 1/95 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L + L+ N I +P F + +L LHL NN++ G + L L+
Sbjct: 133 LPALQAMTLALNRISHIPDYAFQNLTSLVVLHLHNNRIQHLGTHSFEGL------HNLET 186
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 428
LDL NKL P AI L +L L ++N I +P
Sbjct: 187 LDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 221
>BC026112-1|AAH26112.1| 116|Homo sapiens hypothetical protein
LOC401387 protein.
Length = 116
Score = 48.8 bits (111), Expect = 2e-05
Identities = 33/99 (33%), Positives = 47/99 (47%), Gaps = 2/99 (2%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQI--TKTLK 536
+ L LD+SNN I ++P G + NL LH NNQ+ L P + L+
Sbjct: 1 MTQLKELDISNNAIREIPRNIGELRNLVSLHAYNNQIS---------YLPPSLLSLNDLQ 51
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 419
L+L+ N L LP AI + L + +DN + R P I
Sbjct: 52 QLNLSGNNLTALPSAICNIFSLKEINFDDNPLLRPPVEI 90
Score = 33.5 bits (73), Expect = 0.87
Identities = 19/57 (33%), Positives = 31/57 (54%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
L+ L +S + R+I L++L L NN+I LPP + +L +L+L+ N L
Sbjct: 4 LKELDISNNAIREIPRNIGELRNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNL 60
Score = 32.3 bits (70), Expect = 2.0
Identities = 18/73 (24%), Positives = 34/73 (46%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
+ L L +N++ +LP ++ L L L + N ++ LP+ I I +L+ N L
Sbjct: 25 RNLVSLHAYNNQISYLPPSLLSLNDLQQLNLSGNNLTALPSAICNIFSLKEINFDDNPLL 84
Query: 367 SLPCSLMQCRLEY 329
P + + + Y
Sbjct: 85 RPPVEICKGKQLY 97
>BC036337-1|AAH36337.1| 811|Homo sapiens KIAA0644 gene product
protein.
Length = 811
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/121 (35%), Positives = 63/121 (52%), Gaps = 5/121 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIE---KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
L L L+LS NE++ + F + +LS L L+ N L G ++ L P+ L
Sbjct: 202 LGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHL--PR----L 255
Query: 538 KLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQS 365
LL L N+L HL P+A W LE L L+ N +S+LP A + + +L +S NEL +
Sbjct: 256 GLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSA 315
Query: 364 L 362
L
Sbjct: 316 L 316
Score = 38.7 bits (86), Expect = 0.023
Identities = 48/159 (30%), Positives = 71/159 (44%), Gaps = 22/159 (13%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRR-DILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANN 605
P + + L G + N D L L LDL N+I L P+ F +++ L EL+L NN
Sbjct: 58 PHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNN 117
Query: 604 QL-----GVRGVVDWRWLL---GPQITK----------TLKLLDLTSNKLGHLPKAIWK- 482
L G + +L G +I++ +L L L N LG LP A++
Sbjct: 118 LLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAP 177
Query: 481 LEKLVTLKANDNMISRLPAT-IGRISTLRYFTISSNELQ 368
L L+ L N I L ++ LR+ +S+NELQ
Sbjct: 178 LGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQ 216
Score = 37.5 bits (83), Expect = 0.054
Identities = 25/59 (42%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKH-LAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQL 599
L+ L L G +L +L H L LDLS NE+ L P FG + L EL L NN L
Sbjct: 279 LRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNAL 337
>AB014544-1|BAA31619.2| 887|Homo sapiens KIAA0644 protein protein.
Length = 887
Score = 48.0 bits (109), Expect = 4e-05
Identities = 43/121 (35%), Positives = 63/121 (52%), Gaps = 5/121 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIE---KLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
L L L+LS NE++ + F + +LS L L+ N L G ++ L P+ L
Sbjct: 278 LGKLRFLNLSANELQPSLRHAATFAPLRSLSSLILSANSLQHLGPRIFQHL--PR----L 331
Query: 538 KLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQS 365
LL L N+L HL P+A W LE L L+ N +S+LP A + + +L +S NEL +
Sbjct: 332 GLLSLRGNQLTHLAPEAFWGLEALRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSA 391
Query: 364 L 362
L
Sbjct: 392 L 392
Score = 38.7 bits (86), Expect = 0.023
Identities = 48/159 (30%), Positives = 71/159 (44%), Gaps = 22/159 (13%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRR-DILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANN 605
P + + L G + N D L L LDL N+I L P+ F +++ L EL+L NN
Sbjct: 134 PHDVLTYSLGGNFITNITAFDFHRLGQLRRLDLQYNQIRSLHPKTFEKLSRLEELYLGNN 193
Query: 604 QL-----GVRGVVDWRWLL---GPQITK----------TLKLLDLTSNKLGHLPKAIWK- 482
L G + +L G +I++ +L L L N LG LP A++
Sbjct: 194 LLQALAPGTLAPLRKLRILYANGNEISRLSRGSFEGLESLVKLRLDGNALGALPDAVFAP 253
Query: 481 LEKLVTLKANDNMISRLPAT-IGRISTLRYFTISSNELQ 368
L L+ L N I L ++ LR+ +S+NELQ
Sbjct: 254 LGNLLYLHLESNRIRFLGKNAFAQLGKLRFLNLSANELQ 292
Score = 37.5 bits (83), Expect = 0.054
Identities = 25/59 (42%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLLKH-LAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQL 599
L+ L L G +L +L H L LDLS NE+ L P FG + L EL L NN L
Sbjct: 355 LRELRLEGNRLSQLPTALLEPLHSLEALDLSGNELSALHPATFGHLGRLRELSLRNNAL 413
>BC068575-1|AAH68575.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 47.6 bits (108), Expect = 5e-05
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 2/118 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L +LDLS N+I LP F +ANLS L L N+L +R L + L+
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL------RRLER 128
Query: 532 LDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L L N++ H+ P A L++L+ LK DN + LP R+ L +S N L +L
Sbjct: 129 LYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSLLAL 184
Score = 33.9 bits (74), Expect = 0.66
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ LYL ++ + + L L L L +NE+ LPP R+ L L L++N L
Sbjct: 124 RRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSL 181
Query: 598 GVR--GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLP 428
G++D T ++ L L L L + ++ +L L L +DN + R+P
Sbjct: 182 LALEPGILD---------TANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP 232
Query: 427 ATIGRISTLRYFTISSN 377
I + L ++ N
Sbjct: 233 PVIRGLRGLTRLRLAGN 249
>BC013767-1|AAH13767.1| 601|Homo sapiens VASN protein protein.
Length = 601
Score = 47.6 bits (108), Expect = 5e-05
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 2/118 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L +LDLS N+I LP F +ANLS L L N+L +R L + L+
Sbjct: 3 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL------RRLER 56
Query: 532 LDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L L N++ H+ P A L++L+ LK DN + LP R+ L +S N L +L
Sbjct: 57 LYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSLLAL 112
Score = 33.9 bits (74), Expect = 0.66
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ LYL ++ + + L L L L +NE+ LPP R+ L L L++N L
Sbjct: 52 RRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSL 109
Query: 598 GVR--GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLP 428
G++D T ++ L L L L + ++ +L L L +DN + R+P
Sbjct: 110 LALEPGILD---------TANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP 160
Query: 427 ATIGRISTLRYFTISSN 377
I + L ++ N
Sbjct: 161 PVIRGLRGLTRLRLAGN 177
>AY358299-1|AAQ88666.1| 673|Homo sapiens CSRV314 protein.
Length = 673
Score = 47.6 bits (108), Expect = 5e-05
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 2/118 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L +LDLS N+I LP F +ANLS L L N+L +R L + L+
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL------RRLER 128
Query: 532 LDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L L N++ H+ P A L++L+ LK DN + LP R+ L +S N L +L
Sbjct: 129 LYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSLLAL 184
Score = 33.9 bits (74), Expect = 0.66
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ LYL ++ + + L L L L +NE+ LPP R+ L L L++N L
Sbjct: 124 RRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSL 181
Query: 598 GVR--GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLP 428
G++D T ++ L L L L + ++ +L L L +DN + R+P
Sbjct: 182 LALEPGILD---------TANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP 232
Query: 427 ATIGRISTLRYFTISSN 377
I + L ++ N
Sbjct: 233 PVIRGLRGLTRLRLAGN 249
>AY166584-1|AAO27704.1| 673|Homo sapiens vasorin protein.
Length = 673
Score = 47.6 bits (108), Expect = 5e-05
Identities = 42/118 (35%), Positives = 59/118 (50%), Gaps = 2/118 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L +LDLS N+I LP F +ANLS L L N+L +R L + L+
Sbjct: 75 LPGLQLLDLSQNQIASLPSGVFQPLANLSNLDLTANRLHEITNETFRGL------RRLER 128
Query: 532 LDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
L L N++ H+ P A L++L+ LK DN + LP R+ L +S N L +L
Sbjct: 129 LYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSLLAL 184
Score = 33.9 bits (74), Expect = 0.66
Identities = 37/137 (27%), Positives = 61/137 (44%), Gaps = 4/137 (2%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDIL-LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
R L+ LYL ++ + + L L L L +NE+ LPP R+ L L L++N L
Sbjct: 124 RRLERLYLGKNRIRHIQPGAFDTLDRLLELKLQDNELRALPPL--RLPRLLLLDLSHNSL 181
Query: 598 GVR--GVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRLP 428
G++D T ++ L L L L + ++ +L L L +DN + R+P
Sbjct: 182 LALEPGILD---------TANVEALRLAGLGLQQLDEGLFSRLRNLHDLDVSDNQLERVP 232
Query: 427 ATIGRISTLRYFTISSN 377
I + L ++ N
Sbjct: 233 PVIRGLRGLTRLRLAGN 249
>AL356953-5|CAI15931.1| 232|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 232
Score = 47.6 bits (108), Expect = 5e-05
Identities = 35/109 (32%), Positives = 58/109 (53%), Gaps = 2/109 (1%)
Frame = -2
Query: 679 NNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHL 500
NN E P F + L EL L+ N L + + G +LK+L L +N+LG +
Sbjct: 2 NNLTELQPGLFHHLRFLEELRLSGNHLSH---IPGQAFSG---LYSLKILMLQNNQLGGI 55
Query: 499 P-KAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 359
P +A+W+L L +L+ + N+IS +P + +S+LR+ + N L +P
Sbjct: 56 PAEALWELPSLQSLRLDANLISLVPERSFEGLSSLRHLWLDDNALTEIP 104
Score = 37.1 bits (82), Expect = 0.071
Identities = 40/140 (28%), Positives = 64/140 (45%), Gaps = 4/140 (2%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L L L +N + ++P + L + LA N++ + D+ + Q +L +
Sbjct: 87 LSSLRHLWLDDNALTEIPVRALNNLPALQAMTLALNRIS--HIPDYAF----QNLTSLVV 140
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNM-ISRLPATIGRISTLRYFTISSNELQSLPC 356
LDL NKL P AI L +L L N M I P G S L T++ ++ LP
Sbjct: 141 LDLNYNKLQEFPVAIRTLGRLQELSLNGAMDIQEFPDLKGTTS-LEILTLTRAGIRLLPS 199
Query: 355 SLMQ--CRLEYIDISSNKFD 302
+ Q RL +++S N+ +
Sbjct: 200 GMCQQLPRLRVLELSHNQIE 219
>DQ013130-1|AAY67799.1| 2014|Homo sapiens leucine-rich repeat kinase
1 protein.
Length = 2014
Score = 47.2 bits (107), Expect = 7e-05
Identities = 45/137 (32%), Positives = 70/137 (51%), Gaps = 10/137 (7%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFG-RMANLSELHLANNQLG-VRGVVDWRWLLGPQITKTLKLLDLTS 518
LDLS N + LP + NL +L+L++N LG + GV ++ ++ + +D++S
Sbjct: 282 LDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEIICSRLLE----IDISS 337
Query: 517 NKLGHLPKAIWKLEKLVTLKANDNMISRL----PAT--IGRISTLRYFTISSNELQSLPC 356
NKL HLP L KL L A+ N + +L AT IG + L+ IS N+L LP
Sbjct: 338 NKLSHLPPGFLHLSKLQKLTASKNCLEKLFEEENATNWIG-LRKLQELDISDNKLTELPA 396
Query: 355 SLMQC--RLEYIDISSN 311
+ L +++S N
Sbjct: 397 LFLHSFKSLNSLNVSRN 413
Score = 37.5 bits (83), Expect = 0.054
Identities = 37/146 (25%), Positives = 68/146 (46%), Gaps = 6/146 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEF-GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L+ L LD+S+N++ +LP F +L+ L+++ N L V W LK
Sbjct: 378 LRKLQELDISDNKLTELPALFLHSFKSLNSLNVSRNNLKV---FPDPWAC------PLKC 428
Query: 532 LDLTSNKLGHLPKAI---WKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
+ N L LP + WK L + ++N + +P + ++ L + + N+L +L
Sbjct: 429 CKASRNALECLPDKMAVFWK-NHLKDVDFSENALKEVPLGLFQLDALMFLRLQGNQLAAL 487
Query: 361 -PCSLMQCR-LEYIDISSNKFDNKQN 290
P CR L+ +D+S N+ ++
Sbjct: 488 PPQEKWTCRQLKTLDLSRNQLGKNED 513
Score = 37.1 bits (82), Expect = 0.071
Identities = 37/145 (25%), Positives = 64/145 (44%), Gaps = 8/145 (5%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL----GVRGVVDWRWLLGPQ 554
D ++ L +D+S+N++ LPP F ++ L +L + N L +W L
Sbjct: 323 DEIICSRLLEIDISSNKLSHLPPGFLHLSKLQKLTASKNCLEKLFEEENATNWIGL---- 378
Query: 553 ITKTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSN 377
+ L+ LD++ NKL LP + + L +L + N + P L+ S N
Sbjct: 379 --RKLQELDISDNKLTELPALFLHSFKSLNSLNVSRNNLKVFPDPWA--CPLKCCKASRN 434
Query: 376 ELQSLPCSL---MQCRLEYIDISSN 311
L+ LP + + L+ +D S N
Sbjct: 435 ALECLPDKMAVFWKNHLKDVDFSEN 459
Score = 33.5 bits (73), Expect = 0.87
Identities = 20/52 (38%), Positives = 30/52 (57%), Gaps = 1/52 (1%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNE-IEKLPPEFGRMANLSEL 620
+L+ L L+ L + LLK L+ L L NN + +LPPE G++ NL +L
Sbjct: 548 SLEVLCLNDNHLDTVPPSVCLLKSLSELYLGNNPGLRELPPELGQLGNLWQL 599
Score = 32.7 bits (71), Expect = 1.5
Identities = 15/36 (41%), Positives = 24/36 (66%)
Frame = -2
Query: 712 LLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN 605
L + L VL L++N ++ +PP + +LSEL+L NN
Sbjct: 545 LSESLEVLCLNDNHLDTVPPSVCLLKSLSELYLGNN 580
>BC146759-1|AAI46760.1| 1523|Homo sapiens slit homolog 3 (Drosophila)
protein.
Length = 1523
Score = 46.8 bits (106), Expect = 9e-05
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQ 602
P+ + LYL G L R++ L+HL ++DLSNN I L F M++LS L L+ N+
Sbjct: 751 PKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 810
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 494
L V + L ++L++L L N + +P+
Sbjct: 811 LRCIPVHAFNGL------RSLRVLTLHGNDISSVPE 840
Score = 41.1 bits (92), Expect = 0.004
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 5/115 (4%)
Frame = -2
Query: 691 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLT 521
LDL N I ++ +F + NL LHL +NQ+ V RG Q K L+ L L
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAF--------QDLKQLERLRLN 117
Query: 520 SNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGR-ISTLRYFTISSNELQSL 362
NKL LP+ +++ KL L ++N I +P R I+ ++ + +N + +
Sbjct: 118 KNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCI 172
>BC082244-1|AAH82244.1| 465|Homo sapiens PHLPP protein protein.
Length = 465
Score = 46.8 bits (106), Expect = 9e-05
Identities = 38/150 (25%), Positives = 67/150 (44%), Gaps = 12/150 (8%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDW--RWLLGPQ-- 554
++ L+H+ LDL +N++ L N+ LH NQL + + + L
Sbjct: 50 EVDFLQHVTQLDLRDNKLGDLDAMI--FNNIEVLHCERNQLVTLDICGYFLKALYASSNE 107
Query: 553 --------ITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLR 398
+ L +D++ N+L ++P+ + + KL L N I LPA + S+LR
Sbjct: 108 LVQLDVYPVPNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLR 167
Query: 397 YFTISSNELQSLPCSLMQCRLEYIDISSNK 308
N+L LP L + +E +D+ N+
Sbjct: 168 KLLAGHNQLARLPERLERTSVEVLDVQHNQ 197
Score = 44.0 bits (99), Expect = 6e-04
Identities = 42/144 (29%), Positives = 68/144 (47%), Gaps = 8/144 (5%)
Frame = -2
Query: 715 LLLK--HLAVLDLSNNEIEKLPPE-FGRMAN--LSELHLANNQLGVRGVVDWRWLLGPQI 551
LL+K L L+ S N++E LPP N L EL+L NN L + V P +
Sbjct: 205 LLMKADSLRFLNASANKLESLPPATLSEETNSILQELYLTNNSLTDKCV--------PLL 256
Query: 550 T--KTLKLLDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISS 380
T LK+L + N+L P + + KLE+L + + N + +P TI + S
Sbjct: 257 TGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNKLKAIPTTIMNCRRMHTVIAHS 316
Query: 379 NELQSLPCSLMQCRLEYIDISSNK 308
N ++ P + ++ +D+S N+
Sbjct: 317 NCIEVFPEVMQLPEIKCVDLSCNE 340
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/95 (26%), Positives = 51/95 (53%), Gaps = 2/95 (2%)
Frame = -2
Query: 550 TKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
++ L++LD+ N++ LP ++ L L A N ++RLP + R S + + N+L
Sbjct: 140 SRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQLARLPERLERTS-VEVLDVQHNQL 198
Query: 370 QSLPCSLMQ--CRLEYIDISSNKFDNKQNNSTSDQ 272
LP +L+ L +++ S+NK ++ + S++
Sbjct: 199 LELPPNLLMKADSLRFLNASANKLESLPPATLSEE 233
Score = 36.3 bits (80), Expect = 0.12
Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 22/179 (12%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
P L + +S +L N + + L VLD+ +N+I +LP ++L +L +NQL
Sbjct: 117 PNYLSYMDVSRNRLENVPEWVCESRKLEVLDIGHNQICELPARLFCNSSLRKLLAGHNQL 176
Query: 598 G------------VRGVVDWRWL-LGPQI---TKTLKLLDLTSNKLGHLPKAIWKLEKLV 467
V V + L L P + +L+ L+ ++NKL LP A E
Sbjct: 177 ARLPERLERTSVEVLDVQHNQLLELPPNLLMKADSLRFLNASANKLESLPPATLSEETNS 236
Query: 466 TLK----ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNK 308
L+ N+++ + + L+ ++ N LQS P S M LE ID+S NK
Sbjct: 237 ILQELYLTNNSLTDKCVPLLTGHPHLKILHMAYNRLQSFPASKMAKLEELEEIDLSGNK 295
Score = 31.1 bits (67), Expect = 4.7
Identities = 26/78 (33%), Positives = 35/78 (44%)
Frame = -2
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
LDL NKLG L I+ + L N + L G L+ SSNEL L
Sbjct: 60 LDLRDNKLGDLDAMIFN--NIEVLHCERNQLVTLDIC-GYF--LKALYASSNELVQLDVY 114
Query: 352 LMQCRLEYIDISSNKFDN 299
+ L Y+D+S N+ +N
Sbjct: 115 PVPNYLSYMDVSRNRLEN 132
>BC057786-1|AAH57786.1| 512|Homo sapiens podocan-like 1 protein.
Length = 512
Score = 46.8 bits (106), Expect = 9e-05
Identities = 41/141 (29%), Positives = 71/141 (50%), Gaps = 6/141 (4%)
Frame = -2
Query: 712 LLKHLAVLDLSNNEI-EKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLK 536
L + L V DL+ N++ E P FG L ++L NNQL G+ + + ++ +
Sbjct: 143 LPRSLRVADLAANQVMEIFPLTFGEKPALRSVYLHNNQLSNAGLPPDAF----RGSEAIA 198
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNEL--QS 365
L L++N+L +LP ++ L L +N+IS++P + R + LR + N+L
Sbjct: 199 TLSLSNNQLSYLPPSL--PPSLERLHLQNNLISKVPRGALSRQTQLRELYLQHNQLTDSG 256
Query: 364 LPCSLMQ--CRLEYIDISSNK 308
L + LEY+D+S N+
Sbjct: 257 LDATTFSKLHSLEYLDLSHNQ 277
>AY358884-1|AAQ89243.1| 1523|Homo sapiens SLIT3 protein.
Length = 1523
Score = 46.8 bits (106), Expect = 9e-05
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQ 602
P+ + LYL G L R++ L+HL ++DLSNN I L F M++LS L L+ N+
Sbjct: 751 PKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 810
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 494
L V + L ++L++L L N + +P+
Sbjct: 811 LRCIPVHAFNGL------RSLRVLTLHGNDISSVPE 840
Score = 41.1 bits (92), Expect = 0.004
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 5/115 (4%)
Frame = -2
Query: 691 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLT 521
LDL N I ++ +F + NL LHL +NQ+ V RG Q K L+ L L
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAF--------QDLKQLERLRLN 117
Query: 520 SNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGR-ISTLRYFTISSNELQSL 362
NKL LP+ +++ KL L ++N I +P R I+ ++ + +N + +
Sbjct: 118 KNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCI 172
>AF075240-1|AAD19336.1| 850|Homo sapiens SLIT1 protein protein.
Length = 850
Score = 46.8 bits (106), Expect = 9e-05
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQ 602
P+ + LYL G L R++ L+HL ++DLSNN I L F M++LS L L+ N+
Sbjct: 178 PKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 237
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 494
L V + L ++L++L L N + +P+
Sbjct: 238 LRCIPVHAFNGL------RSLRVLTLHGNDISSVPE 267
>AB017169-1|BAA35186.1| 1523|Homo sapiens Slit-3 protein protein.
Length = 1523
Score = 46.8 bits (106), Expect = 9e-05
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQ 602
P+ + LYL G L R++ L+HL ++DLSNN I L F M++LS L L+ N+
Sbjct: 751 PKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 810
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 494
L V + L ++L++L L N + +P+
Sbjct: 811 LRCIPVHAFNGL------RSLRVLTLHGNDISSVPE 840
Score = 41.1 bits (92), Expect = 0.004
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 5/115 (4%)
Frame = -2
Query: 691 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLT 521
LDL N I ++ +F + NL LHL +NQ+ V RG Q K L+ L L
Sbjct: 66 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAF--------QDLKQLERLRLN 117
Query: 520 SNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGR-ISTLRYFTISSNELQSL 362
NKL LP+ +++ KL L ++N I +P R I+ ++ + +N + +
Sbjct: 118 KNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCI 172
>AB011538-1|BAA32466.2| 1559|Homo sapiens MEGF5 protein.
Length = 1559
Score = 46.8 bits (106), Expect = 9e-05
Identities = 32/96 (33%), Positives = 51/96 (53%), Gaps = 1/96 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQ 602
P+ + LYL G L R++ L+HL ++DLSNN I L F M++LS L L+ N+
Sbjct: 787 PKDVTELYLEGNHLTAVPRELSALRHLTLIDLSNNSISMLTNYTFSNMSHLSTLILSYNR 846
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 494
L V + L ++L++L L N + +P+
Sbjct: 847 LRCIPVHAFNGL------RSLRVLTLHGNDISSVPE 876
Score = 41.1 bits (92), Expect = 0.004
Identities = 35/115 (30%), Positives = 56/115 (48%), Gaps = 5/115 (4%)
Frame = -2
Query: 691 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLT 521
LDL N I ++ +F + NL LHL +NQ+ V RG Q K L+ L L
Sbjct: 102 LDLDRNNITRITKMDFAGLKNLRVLHLEDNQVSVIERGAF--------QDLKQLERLRLN 153
Query: 520 SNKLGHLPKAIWK-LEKLVTLKANDNMISRLPATIGR-ISTLRYFTISSNELQSL 362
NKL LP+ +++ KL L ++N I +P R I+ ++ + +N + +
Sbjct: 154 KNKLQVLPELLFQSTPKLTRLDLSENQIQGIPRKAFRGITDVKNLQLDNNHISCI 208
>BC129927-1|AAI29928.1| 1323|Homo sapiens PH domain and leucine rich
repeat protein phosphatase-like protein.
Length = 1323
Score = 46.4 bits (105), Expect = 1e-04
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 3/137 (2%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN--QLGVRGVVDWRWLLGPQITKTLKL 533
+ ++ +DLS +E++P +++ L+L +N QL G +D + LK
Sbjct: 249 QRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQ-----LKG 303
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L+L+ NKLG P + ++ L L + N LP+ IG + L+ + N L +LP
Sbjct: 304 LNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEE 363
Query: 352 LMQC-RLEYIDISSNKF 305
L +L + IS N F
Sbjct: 364 LGNLQQLSSLGISFNNF 380
Score = 44.8 bits (101), Expect = 4e-04
Identities = 49/164 (29%), Positives = 77/164 (46%), Gaps = 9/164 (5%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDIL--LLKH--LAVLDLSNNEIEKLPPE-FGRMANLSELHLA 611
R L SL L L L + L L++H L VLDL +N + +LP F + NL L+ +
Sbjct: 543 RILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNAS 602
Query: 610 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMIS 437
N L G + L+LL LT+N L +P + L + AN N +
Sbjct: 603 ANSLESLPSA----CTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLHLRILHLAN-NQLQ 657
Query: 436 RLPAT-IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
PA+ + ++ L +S N+L+++P ++ C RL + SN
Sbjct: 658 TFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSN 701
Score = 44.4 bits (100), Expect = 5e-04
Identities = 39/135 (28%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEFGRMANLSEL---HLANNQLGVRGVVDWRWLLGPQITKTLKL 533
+L L+ S N +E LP +LS L +L NN L + + L+G L++
Sbjct: 595 NLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPV---LVGHL---HLRI 648
Query: 532 LDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
L L +N+L P + + KLE+L L + N + +P TI L SN + P
Sbjct: 649 LHLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPE 708
Query: 355 SLMQCRLEYIDISSN 311
L +++++D+S N
Sbjct: 709 ILQLPQIQFVDLSCN 723
>AK124678-1|BAC85924.1| 423|Homo sapiens protein ( Homo sapiens
cDNA FLJ42687 fis, clone BRAMY3001794, moderately
similar to Rattus norvegicus SCN circadian oscillatory
protein (Scop). ).
Length = 423
Score = 46.4 bits (105), Expect = 1e-04
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 3/137 (2%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN--QLGVRGVVDWRWLLGPQITKTLKL 533
+ ++ +DLS +E++P +++ L+L +N QL G +D + LK
Sbjct: 249 QRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQ-----LKG 303
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L+L+ NKLG P + ++ L L + N LP+ IG + L+ + N L +LP
Sbjct: 304 LNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEE 363
Query: 352 LMQC-RLEYIDISSNKF 305
L +L + IS N F
Sbjct: 364 LGNLQQLSSLGISFNNF 380
>AB023148-1|BAA76775.2| 1258|Homo sapiens KIAA0931 protein protein.
Length = 1258
Score = 46.4 bits (105), Expect = 1e-04
Identities = 39/137 (28%), Positives = 66/137 (48%), Gaps = 3/137 (2%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANN--QLGVRGVVDWRWLLGPQITKTLKL 533
+ ++ +DLS +E++P +++ L+L +N QL G +D + LK
Sbjct: 251 QRISTVDLSCYSLEEVPEHLFYSQDITYLNLRHNFMQLERPGGLDTLYKFSQ-----LKG 305
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L+L+ NKLG P + ++ L L + N LP+ IG + L+ + N L +LP
Sbjct: 306 LNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTLPEE 365
Query: 352 LMQC-RLEYIDISSNKF 305
L +L + IS N F
Sbjct: 366 LGNLQQLSSLGISFNNF 382
Score = 45.2 bits (102), Expect = 3e-04
Identities = 41/140 (29%), Positives = 63/140 (45%), Gaps = 8/140 (5%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
K + VLD+S N + ++P LS L L LG V + L+ I L++LD
Sbjct: 527 KKIEVLDVSYNLLTEVPVRI-----LSSLSLRKLMLGHNHVQNLPTLV-EHIP--LEVLD 578
Query: 526 LTSNKLGHLPKAIW--------KLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNEL 371
L N L LP ++ KLE+L L + N + +P TI L SN +
Sbjct: 579 LQHNALTRLPDTLFSKALNKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNI 638
Query: 370 QSLPCSLMQCRLEYIDISSN 311
P L +++++D+S N
Sbjct: 639 SIFPEILQLPQIQFVDLSCN 658
>BC150568-1|AAI50569.1| 370|Homo sapiens leucine-rich repeats and
transmembrane domains 2 protein.
Length = 370
Score = 45.2 bits (102), Expect = 3e-04
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 5/141 (3%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L LDLSNN +++LP FG + NL+EL L NN + +D R LL + + L+
Sbjct: 91 LSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSI---RTLD-RDLL--RHSPLLRH 144
Query: 532 LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 359
LDL+ N L LP ++ L L +L N + L T ++ L+ + N +
Sbjct: 145 LDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWE-CD 203
Query: 358 CSLMQCR--LEYIDISSNKFD 302
C+L + + +E+ + D
Sbjct: 204 CNLREFKHWMEWFSYRGGRLD 224
>BC035267-1|AAH35267.1| 723|Homo sapiens PHLPPL protein protein.
Length = 723
Score = 45.2 bits (102), Expect = 3e-04
Identities = 49/164 (29%), Positives = 78/164 (47%), Gaps = 9/164 (5%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDIL--LLKH--LAVLDLSNNEIEKLPPE-FGRMANLSELHLA 611
R L SL L L L + L L++H L VLDL +N + +LP F + NL L+ +
Sbjct: 281 RILSSLSLRKLMLGHNHVQNLPTLVEHIPLEVLDLQHNALTRLPDTLFSKALNLRYLNAS 340
Query: 610 NNQLGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGH--LPKAIWKLEKLVTLKANDNMIS 437
N L G + L+LL LT+N L +P + L L L+ +N +
Sbjct: 341 ANSLESLPSA----CTGEESLSMLQLLYLTNNLLTDQCIPVLVGHLH-LRILRLANNQLQ 395
Query: 436 RLPAT-IGRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSN 311
PA+ + ++ L +S N+L+++P ++ C RL + SN
Sbjct: 396 TFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSN 439
Score = 44.0 bits (99), Expect = 6e-04
Identities = 39/135 (28%), Positives = 64/135 (47%), Gaps = 4/135 (2%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEFGRMANLSEL---HLANNQLGVRGVVDWRWLLGPQITKTLKL 533
+L L+ S N +E LP +LS L +L NN L + + L+G L++
Sbjct: 333 NLRYLNASANSLESLPSACTGEESLSMLQLLYLTNNLLTDQCIPV---LVGHL---HLRI 386
Query: 532 LDLTSNKLGHLPKA-IWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPC 356
L L +N+L P + + KLE+L L + N + +P TI L SN + P
Sbjct: 387 LRLANNQLQTFPASKLNKLEQLEELNLSGNKLKTIPTTIANCKRLHTLVAHSNNISIFPE 446
Query: 355 SLMQCRLEYIDISSN 311
L +++++D+S N
Sbjct: 447 ILQLPQIQFVDLSCN 461
Score = 40.7 bits (91), Expect = 0.006
Identities = 27/80 (33%), Positives = 40/80 (50%), Gaps = 1/80 (1%)
Frame = -2
Query: 541 LKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSL 362
LK L+L+ NKLG P + ++ L L + N LP+ IG + L+ + N L +L
Sbjct: 39 LKGLNLSHNKLGLFPILLCEISTLTELNLSCNGFHDLPSQIGNLLNLQTLCLDGNFLTTL 98
Query: 361 PCSLMQC-RLEYIDISSNKF 305
P L +L + IS N F
Sbjct: 99 PEELGNLQQLSSLGISFNNF 118
>AL356953-4|CAI15930.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 212 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 264
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 398
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 265 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 310
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/96 (36%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLK 536
L+ L L LS N + +P + F + +L L L NNQLG G+ + W L +L+
Sbjct: 46 LRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG--GIPAEALWEL-----PSLQ 98
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 428
LDL NKL P AI L +L L ++N I +P
Sbjct: 99 SLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 134
Score = 37.1 bits (82), Expect = 0.071
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 4/159 (2%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMAN--LSELHLANNQL 599
+LQSL L+ KL F I L L L NN I+ + PE M N L +H +N +
Sbjct: 96 SLQSLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAI-PEKAFMGNPLLQTIHFYDNPI 154
Query: 598 GVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 419
G +++L P++ TL L + K LE L +A I LP+ +
Sbjct: 155 QFVGRSAFQYL--PKL-HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAG---IRLLPSGM 208
Query: 418 -GRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 308
++ LR +S N+++ LP SL +C +LE I + N+
Sbjct: 209 CQQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGLQHNR 246
>AK095610-1|BAC04589.1| 370|Homo sapiens protein ( Homo sapiens
cDNA FLJ38291 fis, clone FCBBF3009069, weakly similar to
Homo sapiens HT017 mRNA. ).
Length = 370
Score = 45.2 bits (102), Expect = 3e-04
Identities = 43/141 (30%), Positives = 69/141 (48%), Gaps = 5/141 (3%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L LDLSNN +++LP FG + NL+EL L NN + +D R LL + + L+
Sbjct: 91 LSSLQRLDLSNNFLDRLPRSIFGDLTNLTELQLRNNSI---RTLD-RDLL--RHSPLLRH 144
Query: 532 LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLP 359
LDL+ N L LP ++ L L +L N + L T ++ L+ + N +
Sbjct: 145 LDLSINGLAQLPPGLFDGLLALRSLSLRSNRLQNLDRLTFEPLANLQLLQVGDNPWE-CD 203
Query: 358 CSLMQCR--LEYIDISSNKFD 302
C+L + + +E+ + D
Sbjct: 204 CNLREFKHWMEWFSYRGGRLD 224
>AF190501-1|AAG17168.1| 828|Homo sapiens leucine-rich
repeat-containing G protein-coupled receptor 6 protein.
Length = 828
Score = 45.2 bits (102), Expect = 3e-04
Identities = 36/106 (33%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L VL+LS+N+IE+L P R L E+ L +N++ G + L +L+ L
Sbjct: 212 LPRLRVLELSHNQIEEL-PSLHRCQKLEEIGLQHNRIWEIGADTFSQL------SSLQAL 264
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLP-ATIGRISTLR 398
DL+ N + + P+A L LV L DN ++ LP A +G + L+
Sbjct: 265 DLSWNAIRSIHPEAFSTLHSLVKLDLTDNQLTTLPLAGLGGLMHLK 310
Score = 41.9 bits (94), Expect = 0.002
Identities = 35/96 (36%), Positives = 49/96 (51%), Gaps = 2/96 (2%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLK 536
L+ L L LS N + +P + F + +L L L NNQLG G+ + W L +L+
Sbjct: 46 LRFLEELRLSGNHLSHIPGQAFSGLYSLKILMLQNNQLG--GIPAEALWEL-----PSLQ 98
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLP 428
LDL NKL P AI L +L L ++N I +P
Sbjct: 99 SLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAIP 134
Score = 37.1 bits (82), Expect = 0.071
Identities = 49/159 (30%), Positives = 75/159 (47%), Gaps = 4/159 (2%)
Frame = -2
Query: 772 TLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMAN--LSELHLANNQL 599
+LQSL L+ KL F I L L L NN I+ + PE M N L +H +N +
Sbjct: 96 SLQSLDLNYNKLQEFPVAIRTLGRLQELGFHNNNIKAI-PEKAFMGNPLLQTIHFYDNPI 154
Query: 598 GVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI 419
G +++L P++ TL L + K LE L +A I LP+ +
Sbjct: 155 QFVGRSAFQYL--PKL-HTLSLNGAMDIQEFPDLKGTTSLEILTLTRAG---IRLLPSGM 208
Query: 418 -GRISTLRYFTISSNELQSLPCSLMQC-RLEYIDISSNK 308
++ LR +S N+++ LP SL +C +LE I + N+
Sbjct: 209 CQQLPRLRVLELSHNQIEELP-SLHRCQKLEEIGLQHNR 246
>BC096326-1|AAH96326.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 44.4 bits (100), Expect = 5e-04
Identities = 37/135 (27%), Positives = 67/135 (49%), Gaps = 1/135 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L LDL+ N +++ P ++NL ELH +N + G ++ L P++ +TL L
Sbjct: 233 LHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHL--PEL-RTLTLN 289
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI-GRISTLRYFTISSNELQSLPCS 353
++++ P + L +L IS LP T+ ++ L+ +S N L+ LP
Sbjct: 290 G--ASQITEFPD-LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSF 346
Query: 352 LMQCRLEYIDISSNK 308
+ +L+ ID+ N+
Sbjct: 347 SVCQKLQKIDLRHNE 361
Score = 38.7 bits (86), Expect = 0.023
Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 3/134 (2%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L + L+ N+I +P FG +++L LHL NN++ G + L +L+
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL------HSLET 238
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTIS-SNELQSLP 359
LDL N L P AI L L L DN I + + + LR T++ ++++ P
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP 298
Query: 358 CSLMQCRLEYIDIS 317
LE + ++
Sbjct: 299 DLTGTANLESLTLT 312
>BC096325-1|AAH96325.1| 883|Homo sapiens LGR5 protein protein.
Length = 883
Score = 44.4 bits (100), Expect = 5e-04
Identities = 37/135 (27%), Positives = 67/135 (49%), Gaps = 1/135 (0%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
L L LDL+ N +++ P ++NL ELH +N + G ++ L P++ +TL L
Sbjct: 233 LHSLETLDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHL--PEL-RTLTLN 289
Query: 529 DLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATI-GRISTLRYFTISSNELQSLPCS 353
++++ P + L +L IS LP T+ ++ L+ +S N L+ LP
Sbjct: 290 G--ASQITEFPD-LTGTANLESLTLTGAQISSLPQTVCNQLPNLQVLDLSYNLLEDLPSF 346
Query: 352 LMQCRLEYIDISSNK 308
+ +L+ ID+ N+
Sbjct: 347 SVCQKLQKIDLRHNE 361
Score = 38.7 bits (86), Expect = 0.023
Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 3/134 (2%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L L + L+ N+I +P FG +++L LHL NN++ G + L +L+
Sbjct: 185 LSALQAMTLALNKIHHIPDYAFGNLSSLVVLHLHNNRIHSLGKKCFDGL------HSLET 238
Query: 532 LDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRYFTIS-SNELQSLP 359
LDL N L P AI L L L DN I + + + LR T++ ++++ P
Sbjct: 239 LDLNYNNLDEFPTAIRTLSNLKELHFYDNPIQFVGRSAFQHLPELRTLTLNGASQITEFP 298
Query: 358 CSLMQCRLEYIDIS 317
LE + ++
Sbjct: 299 DLTGTANLESLTLT 312
>BC030547-1|AAH30547.1| 647|Homo sapiens hypothetical protein
DKFZp434K1815 protein.
Length = 647
Score = 44.4 bits (100), Expect = 5e-04
Identities = 29/61 (47%), Positives = 37/61 (60%), Gaps = 3/61 (4%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILLL---KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
++SL LSGL+L + D LL L LDLSNN +E LP G +++L L ANNQL
Sbjct: 23 IRSLDLSGLELLSEHLDPKLLCRLTQLQELDLSNNHLETLPDNLG-LSHLRVLRCANNQL 81
Query: 598 G 596
G
Sbjct: 82 G 82
>Y19205-1|CAC80724.1| 845|Homo sapiens SLITL1 protein.
Length = 845
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 596
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 419
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 418 GRISTLRYFTISSNELQSLP 359
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>BC113012-1|AAI13013.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 596
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 419
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 418 GRISTLRYFTISSNELQSLP 359
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>BC113011-1|AAI13012.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 596
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 419
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 418 GRISTLRYFTISSNELQSLP 359
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>BC030608-1|AAH30608.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 44.0 bits (99), Expect = 6e-04
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 6/152 (3%)
Frame = -2
Query: 748 GLKLCNFRRDILLLKHLAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQLGVRGVVDWR 572
G+ L F D L +H L L NN++EK+ P E R+ L L+L NN+L RG+ +
Sbjct: 132 GIDLREFPGD--LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKA 189
Query: 571 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRY 395
+ + L L L +NKL P+ + L+++ N ++++ T G+ LR
Sbjct: 190 F----EHLTNLNYLYLANNKLTLAPRFL--PNALISVDFAANYLTKIYGLTFGQKPNLRS 243
Query: 394 FTISSNEL--QSLPCSLM--QCRLEYIDISSN 311
+ +N+L LP ++ +E + +SSN
Sbjct: 244 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSN 275
Score = 36.3 bits (80), Expect = 0.12
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = -2
Query: 691 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
L L NN++EK+PP F +++L EL+L NN LT
Sbjct: 291 LHLKNNKLEKIPPGAFSELSSLRELYLQNNY-------------------------LTDE 325
Query: 514 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--C 341
L + + WKL L L + N +SR+PA + R L + + N ++S+ +++
Sbjct: 326 GLDN--ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLH--LEKNAIRSVDANVLTPIR 381
Query: 340 RLEYIDISSNK 308
LEY+ + SN+
Sbjct: 382 SLEYLLLHSNQ 392
Score = 35.5 bits (78), Expect = 0.22
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 5/124 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG--VRGVVDWRWLLGPQITKTLK 536
L+ L LDLS N + LPP G N+ L + N+L RG L G L+
Sbjct: 477 LRLLRSLDLSGNRLHTLPP--GLPRNVHVLKVKRNELAALARGA-----LAG---MAQLR 526
Query: 535 LLDLTSNKLGHL---PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
L LTSN+L P+A L L L N ++ +P G +L Y + +N++ +
Sbjct: 527 ELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE--GLPESLEYLYLQNNKISA 584
Query: 364 LPCS 353
+P +
Sbjct: 585 VPAN 588
>AY358828-1|AAQ89187.1| 733|Homo sapiens LSGV9197 protein.
Length = 733
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 596
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 419
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 418 GRISTLRYFTISSNELQSLP 359
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>AY358316-1|AAQ88682.1| 745|Homo sapiens FPLR1885 protein.
Length = 745
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 3/137 (2%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 602
P + +L LS K+ RR + + L L++NE+ + P G +A LS+L N
Sbjct: 50 PANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEP--GALAVLSQLK--NLD 105
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRL-P 428
L + + W ++ L+LL + N+LG LP+ A+ L L +L+ N+N + L P
Sbjct: 106 LSHNFISSFPWSDLRNLS-ALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAP 164
Query: 427 ATIGRISTLRYFTISSN 377
T +S L + + N
Sbjct: 165 GTFDALSALSHLQLYHN 181
>AY358294-1|AAQ88661.1| 642|Homo sapiens EGEE293 protein.
Length = 642
Score = 44.0 bits (99), Expect = 6e-04
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 6/152 (3%)
Frame = -2
Query: 748 GLKLCNFRRDILLLKHLAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQLGVRGVVDWR 572
G+ L F D L +H L L NN++EK+ P E R+ L L+L NN+L RG+ +
Sbjct: 113 GIDLREFPGD--LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKA 170
Query: 571 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRY 395
+ + L L L +NKL P+ + L+++ N ++++ T G+ LR
Sbjct: 171 F----EHLTNLNYLYLANNKLTLAPRFL--PNALISVDFAANYLTKIYGLTFGQKPNLRS 224
Query: 394 FTISSNEL--QSLPCSLM--QCRLEYIDISSN 311
+ +N+L LP ++ +E + +SSN
Sbjct: 225 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSN 256
Score = 36.3 bits (80), Expect = 0.12
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = -2
Query: 691 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
L L NN++EK+PP F +++L EL+L NN LT
Sbjct: 272 LHLKNNKLEKIPPGAFSELSSLRELYLQNNY-------------------------LTDE 306
Query: 514 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--C 341
L + + WKL L L + N +SR+PA + R L + + N ++S+ +++
Sbjct: 307 GLDN--ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLH--LEKNAIRSVDANVLTPIR 362
Query: 340 RLEYIDISSNK 308
LEY+ + SN+
Sbjct: 363 SLEYLLLHSNQ 373
Score = 35.5 bits (78), Expect = 0.22
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 5/124 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG--VRGVVDWRWLLGPQITKTLK 536
L+ L LDLS N + LPP G N+ L + N+L RG L G L+
Sbjct: 458 LRLLRSLDLSGNRLHTLPP--GLPRNVHVLKVKRNELAALARGA-----LAG---MAQLR 507
Query: 535 LLDLTSNKLGHL---PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
L LTSN+L P+A L L L N ++ +P G +L Y + +N++ +
Sbjct: 508 ELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE--GLPESLEYLYLQNNKISA 565
Query: 364 LPCS 353
+P +
Sbjct: 566 VPAN 569
>AY313607-1|AAP79898.1| 613|Homo sapiens podocan protein protein.
Length = 613
Score = 44.0 bits (99), Expect = 6e-04
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 6/152 (3%)
Frame = -2
Query: 748 GLKLCNFRRDILLLKHLAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQLGVRGVVDWR 572
G+ L F D L +H L L NN++EK+ P E R+ L L+L NN+L RG+ +
Sbjct: 84 GIDLREFPGD--LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKA 141
Query: 571 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRY 395
+ + L L L +NKL P+ + L+++ N ++++ T G+ LR
Sbjct: 142 F----EHLTNLNYLYLANNKLTLAPRFL--PNALISVDFAANYLTKIYGLTFGQKPNLRS 195
Query: 394 FTISSNEL--QSLPCSLM--QCRLEYIDISSN 311
+ +N+L LP ++ +E + +SSN
Sbjct: 196 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSN 227
Score = 36.3 bits (80), Expect = 0.12
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = -2
Query: 691 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
L L NN++EK+PP F +++L EL+L NN LT
Sbjct: 243 LHLKNNKLEKIPPGAFSELSSLRELYLQNNY-------------------------LTDE 277
Query: 514 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--C 341
L + + WKL L L + N +SR+PA + R L + + N ++S+ +++
Sbjct: 278 GLDN--ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLH--LEKNAIRSVDANVLTPIR 333
Query: 340 RLEYIDISSNK 308
LEY+ + SN+
Sbjct: 334 SLEYLLLHSNQ 344
Score = 35.5 bits (78), Expect = 0.22
Identities = 38/124 (30%), Positives = 57/124 (45%), Gaps = 5/124 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG--VRGVVDWRWLLGPQITKTLK 536
L+ L LDLS N + LPP G N+ L + N+L RG L G L+
Sbjct: 429 LRLLRSLDLSGNRLHMLPP--GLPRNVHVLKVKRNELAALARGA-----LAG---MAQLR 478
Query: 535 LLDLTSNKLGHL---PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
L LTSN+L P+A L L L N ++ +P G +L Y + +N++ +
Sbjct: 479 ELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE--GLPESLEYLYLQNNKISA 536
Query: 364 LPCS 353
+P +
Sbjct: 537 VPAN 540
>AL445183-5|CAH72592.1| 642|Homo sapiens podocan protein.
Length = 642
Score = 44.0 bits (99), Expect = 6e-04
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 6/152 (3%)
Frame = -2
Query: 748 GLKLCNFRRDILLLKHLAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQLGVRGVVDWR 572
G+ L F D L +H L L NN++EK+ P E R+ L L+L NN+L RG+ +
Sbjct: 113 GIDLREFPGD--LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKA 170
Query: 571 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRY 395
+ + L L L +NKL P+ + L+++ N ++++ T G+ LR
Sbjct: 171 F----EHLTNLNYLYLANNKLTLAPRFL--PNALISVDFAANYLTKIYGLTFGQKPNLRS 224
Query: 394 FTISSNEL--QSLPCSLM--QCRLEYIDISSN 311
+ +N+L LP ++ +E + +SSN
Sbjct: 225 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSN 256
Score = 36.3 bits (80), Expect = 0.12
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = -2
Query: 691 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
L L NN++EK+PP F +++L EL+L NN LT
Sbjct: 272 LHLKNNKLEKIPPGAFSELSSLRELYLQNNY-------------------------LTDE 306
Query: 514 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--C 341
L + + WKL L L + N +SR+PA + R L + + N ++S+ +++
Sbjct: 307 GLDN--ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLH--LEKNAIRSVDANVLTPIR 362
Query: 340 RLEYIDISSNK 308
LEY+ + SN+
Sbjct: 363 SLEYLLLHSNQ 373
Score = 36.3 bits (80), Expect = 0.12
Identities = 38/124 (30%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG--VRGVVDWRWLLGPQITKTLK 536
L+ L LDLS N + LPP G N+ L + N+L RG L+G L+
Sbjct: 458 LRLLRSLDLSGNRLHTLPP--GLPRNVHVLKVKRNELAALARGA-----LVG---MAQLR 507
Query: 535 LLDLTSNKLGHL---PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
L LTSN+L P+A L L L N ++ +P G +L Y + +N++ +
Sbjct: 508 ELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE--GLPESLEYLYLQNNKISA 565
Query: 364 LPCS 353
+P +
Sbjct: 566 VPAN 569
>AL445183-4|CAH72591.1| 661|Homo sapiens podocan protein.
Length = 661
Score = 44.0 bits (99), Expect = 6e-04
Identities = 44/152 (28%), Positives = 75/152 (49%), Gaps = 6/152 (3%)
Frame = -2
Query: 748 GLKLCNFRRDILLLKHLAVLDLSNNEIEKL-PPEFGRMANLSELHLANNQLGVRGVVDWR 572
G+ L F D L +H L L NN++EK+ P E R+ L L+L NN+L RG+ +
Sbjct: 132 GIDLREFPGD--LPEHTNHLSLQNNQLEKIYPEELSRLHRLETLNLQNNRLTSRGLPEKA 189
Query: 571 WLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRISTLRY 395
+ + L L L +NKL P+ + L+++ N ++++ T G+ LR
Sbjct: 190 F----EHLTNLNYLYLANNKLTLAPRFL--PNALISVDFAANYLTKIYGLTFGQKPNLRS 243
Query: 394 FTISSNEL--QSLPCSLM--QCRLEYIDISSN 311
+ +N+L LP ++ +E + +SSN
Sbjct: 244 VYLHNNKLADAGLPDNMFNGSSNVEVLILSSN 275
Score = 36.3 bits (80), Expect = 0.12
Identities = 37/131 (28%), Positives = 61/131 (46%), Gaps = 3/131 (2%)
Frame = -2
Query: 691 LDLSNNEIEKLPP-EFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
L L NN++EK+PP F +++L EL+L NN LT
Sbjct: 291 LHLKNNKLEKIPPGAFSELSSLRELYLQNNY-------------------------LTDE 325
Query: 514 KLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQ--C 341
L + + WKL L L + N +SR+PA + R L + + N ++S+ +++
Sbjct: 326 GLDN--ETFWKLSSLEYLDLSSNNLSRVPAGLPRSLVLLH--LEKNAIRSVDANVLTPIR 381
Query: 340 RLEYIDISSNK 308
LEY+ + SN+
Sbjct: 382 SLEYLLLHSNQ 392
Score = 36.3 bits (80), Expect = 0.12
Identities = 38/124 (30%), Positives = 58/124 (46%), Gaps = 5/124 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG--VRGVVDWRWLLGPQITKTLK 536
L+ L LDLS N + LPP G N+ L + N+L RG L+G L+
Sbjct: 477 LRLLRSLDLSGNRLHTLPP--GLPRNVHVLKVKRNELAALARGA-----LVG---MAQLR 526
Query: 535 LLDLTSNKLGHL---PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQS 365
L LTSN+L P+A L L L N ++ +P G +L Y + +N++ +
Sbjct: 527 ELYLTSNRLRSRALGPRAWVDLAHLQLLDIAGNQLTEIPE--GLPESLEYLYLQNNKISA 584
Query: 364 LPCS 353
+P +
Sbjct: 585 VPAN 588
>AL109653-2|CAC18888.1| 845|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 845
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 596
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 419
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 418 GRISTLRYFTISSNELQSLP 359
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>AL109653-1|CAI41645.1| 724|Homo sapiens SLIT and NTRK-like family,
member 2 protein.
Length = 724
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 596
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 419
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 418 GRISTLRYFTISSNELQSLP 359
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>AK091015-1|BAC03566.1| 724|Homo sapiens protein ( Homo sapiens
cDNA FLJ33696 fis, clone BRAWH2003964, weakly similar to
SLIT PROTEIN PRECURSOR. ).
Length = 724
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 596
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 64 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 123
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 419
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 124 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 177
Query: 418 GRISTLRYFTISSNELQSLP 359
R L + + N L+ +P
Sbjct: 178 FRFVLLTHLDLRGNRLKVMP 197
>AB058757-1|BAB47483.1| 572|Homo sapiens KIAA1854 protein protein.
Length = 572
Score = 44.0 bits (99), Expect = 6e-04
Identities = 37/140 (26%), Positives = 65/140 (46%), Gaps = 3/140 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQLG 596
+ L+L+G L + + + + L L NN ++++ F + L LHL NN+L
Sbjct: 70 IYQLFLNGNLLTRLYPNEFVNYSNAVTLHLGNNGLQEIRTGAFSGLKTLKRLHLNNNKLE 129
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPATI 419
+ + LG ++L+ L N + + A KL KL L NDN++ LP+ +
Sbjct: 130 I---LREDTFLG---LESLEYLQADYNYISAIEAGAFSKLNKLKVLILNDNLLLSLPSNV 183
Query: 418 GRISTLRYFTISSNELQSLP 359
R L + + N L+ +P
Sbjct: 184 FRFVLLTHLDLRGNRLKVMP 203
>AB040898-1|BAA95989.2| 785|Homo sapiens KIAA1465 protein protein.
Length = 785
Score = 44.0 bits (99), Expect = 6e-04
Identities = 40/137 (29%), Positives = 67/137 (48%), Gaps = 3/137 (2%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQ 602
P + +L LS K+ RR + + L L++NE+ + P G +A LS+L N
Sbjct: 90 PANVTTLSLSANKITVLRRGAFADVTQVTSLWLAHNEVRTVEP--GALAVLSQLK--NLD 145
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRL-P 428
L + + W ++ L+LL + N+LG LP+ A+ L L +L+ N+N + L P
Sbjct: 146 LSHNFISSFPWSDLRNLS-ALQLLKMNHNRLGSLPRDALGALPDLRSLRINNNRLRTLAP 204
Query: 427 ATIGRISTLRYFTISSN 377
T +S L + + N
Sbjct: 205 GTFDALSALSHLQLYHN 221
>BC126410-1|AAI26411.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 43.6 bits (98), Expect = 8e-04
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLK 536
L +L LDLS N++ L PE F + L LHL +N L V + W ++L+
Sbjct: 132 LINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWD-------CRSLE 184
Query: 535 LLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSL 362
LDL++N+L L + L KL L N ++++ A R+S+L + N++ +L
Sbjct: 185 FLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNL 244
Query: 361 PCSLMQC--RLEYIDISSNK 308
C + LE +D++ N+
Sbjct: 245 TCGMEWTWGTLEKLDLTGNE 264
Score = 35.9 bits (79), Expect = 0.16
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 6/164 (3%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 602
R LQ+L+L L + + L LDLS N + L F + L ELHL +NQ
Sbjct: 157 RKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQ 216
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAI-WKLEKLVTLKANDNMISRLPA 425
L + L +L L L NK+ +L + W L L N I +
Sbjct: 217 LTKINFAHFLRL------SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDL 270
Query: 424 TI-GRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNKFD 302
T+ + L+ + +N+L SL ++ L + +S N ++
Sbjct: 271 TVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 314
>BC126408-1|AAI26409.1| 516|Homo sapiens leucine rich repeat
transmembrane neuronal 2 protein.
Length = 516
Score = 43.6 bits (98), Expect = 8e-04
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLK 536
L +L LDLS N++ L PE F + L LHL +N L V + W ++L+
Sbjct: 132 LINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWD-------CRSLE 184
Query: 535 LLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSL 362
LDL++N+L L + L KL L N ++++ A R+S+L + N++ +L
Sbjct: 185 FLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNL 244
Query: 361 PCSLMQC--RLEYIDISSNK 308
C + LE +D++ N+
Sbjct: 245 TCGMEWTWGTLEKLDLTGNE 264
Score = 35.9 bits (79), Expect = 0.16
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 6/164 (3%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 602
R LQ+L+L L + + L LDLS N + L F + L ELHL +NQ
Sbjct: 157 RKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQ 216
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAI-WKLEKLVTLKANDNMISRLPA 425
L + L +L L L NK+ +L + W L L N I +
Sbjct: 217 LTKINFAHFLRL------SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDL 270
Query: 424 TI-GRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNKFD 302
T+ + L+ + +N+L SL ++ L + +S N ++
Sbjct: 271 TVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 314
>BC095477-1|AAH95477.1| 522|Homo sapiens AMIGO2 protein protein.
Length = 522
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
Frame = -2
Query: 712 LLKHLAVLDLSNNEIEKLPPEF--GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
L + + LDLS N I L E+ A L+ L L +N + + T L
Sbjct: 66 LFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSF------STTPNL 119
Query: 538 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQS 365
K LDL+SNKL + A++ +L+ L L +N IS L P+ G +S L+ +S N L
Sbjct: 120 KCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQ 179
Query: 364 LPCSLMQCR-----LEYIDISSNK 308
P L R L ++D+S N+
Sbjct: 180 FPMDLYVGRFKLAELMFLDVSYNR 203
>BC047595-1|AAH47595.1| 522|Homo sapiens adhesion molecule with
Ig-like domain 2 protein.
Length = 522
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
Frame = -2
Query: 712 LLKHLAVLDLSNNEIEKLPPEF--GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
L + + LDLS N I L E+ A L+ L L +N + + T L
Sbjct: 66 LFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSF------STTPNL 119
Query: 538 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQS 365
K LDL+SNKL + A++ +L+ L L +N IS L P+ G +S L+ +S N L
Sbjct: 120 KCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQ 179
Query: 364 LPCSLMQCR-----LEYIDISSNK 308
P L R L ++D+S N+
Sbjct: 180 FPMDLYVGRFKLAELMFLDVSYNR 203
>AY454159-1|AAR83271.1| 522|Homo sapiens DEGA/AMIGO-2 precursor
protein.
Length = 522
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
Frame = -2
Query: 712 LLKHLAVLDLSNNEIEKLPPEF--GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
L + + LDLS N I L E+ A L+ L L +N + + T L
Sbjct: 66 LFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSF------STTPNL 119
Query: 538 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQS 365
K LDL+SNKL + A++ +L+ L L +N IS L P+ G +S L+ +S N L
Sbjct: 120 KCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQ 179
Query: 364 LPCSLMQCR-----LEYIDISSNK 308
P L R L ++D+S N+
Sbjct: 180 FPMDLYVGRFKLAELMFLDVSYNR 203
>AY237005-1|AAO48946.1| 522|Homo sapiens transmembrane protein
AMIGO2 protein.
Length = 522
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
Frame = -2
Query: 712 LLKHLAVLDLSNNEIEKLPPEF--GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
L + + LDLS N I L E+ A L+ L L +N + + T L
Sbjct: 66 LFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSF------STTPNL 119
Query: 538 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQS 365
K LDL+SNKL + A++ +L+ L L +N IS L P+ G +S L+ +S N L
Sbjct: 120 KCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQ 179
Query: 364 LPCSLMQCR-----LEYIDISSNK 308
P L R L ++D+S N+
Sbjct: 180 FPMDLYVGRFKLAELMFLDVSYNR 203
>AY182026-1|AAO67547.1| 516|Homo sapiens leucine-rich repeat
transmembrane neuronal 2 protein protein.
Length = 516
Score = 43.6 bits (98), Expect = 8e-04
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLK 536
L +L LDLS N++ L PE F + L LHL +N L V + W ++L+
Sbjct: 132 LINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWD-------CRSLE 184
Query: 535 LLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSL 362
LDL++N+L L + L KL L N ++++ A R+S+L + N++ +L
Sbjct: 185 FLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNL 244
Query: 361 PCSLMQC--RLEYIDISSNK 308
C + LE +D++ N+
Sbjct: 245 TCGMEWTWGTLEKLDLTGNE 264
Score = 35.9 bits (79), Expect = 0.16
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 6/164 (3%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 602
R LQ+L+L L + + L LDLS N + L F + L ELHL +NQ
Sbjct: 157 RKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQ 216
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAI-WKLEKLVTLKANDNMISRLPA 425
L + L +L L L NK+ +L + W L L N I +
Sbjct: 217 LTKINFAHFLRL------SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDL 270
Query: 424 TI-GRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNKFD 302
T+ + L+ + +N+L SL ++ L + +S N ++
Sbjct: 271 TVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 314
>AB080610-1|BAC81189.1| 522|Homo sapiens alivin 1 protein.
Length = 522
Score = 43.6 bits (98), Expect = 8e-04
Identities = 46/144 (31%), Positives = 68/144 (47%), Gaps = 9/144 (6%)
Frame = -2
Query: 712 LLKHLAVLDLSNNEIEKLPPEF--GRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
L + + LDLS N I L E+ A L+ L L +N + + T L
Sbjct: 66 LFRLIKRLDLSYNRIGLLDSEWIPVSFAKLNTLILRHNNITSISTGSF------STTPNL 119
Query: 538 KLLDLTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQS 365
K LDL+SNKL + A++ +L+ L L +N IS L P+ G +S L+ +S N L
Sbjct: 120 KCLDLSSNKLKTVKNAVFQELKVLEVLLLYNNHISYLDPSAFGGLSQLQKLYLSGNFLTQ 179
Query: 364 LPCSLMQCR-----LEYIDISSNK 308
P L R L ++D+S N+
Sbjct: 180 FPMDLYVGRFKLAELMFLDVSYNR 203
>AB071037-1|BAB84587.1| 581|Homo sapiens Lib protein.
Length = 581
Score = 43.6 bits (98), Expect = 8e-04
Identities = 42/144 (29%), Positives = 67/144 (46%), Gaps = 5/144 (3%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
+L L LSNN I +LPP F ++ L+ L L N L + + GP L+ L
Sbjct: 246 NLQRLYLSNNHISQLPPSIFMQLPQLNRLTLFGNSLKELSL----GIFGPM--PNLRELW 299
Query: 526 LTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCS 353
L N + LP ++ L +L L + N IS + P ++ LR ++ +N LQ L +
Sbjct: 300 LYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGN 359
Query: 352 L--MQCRLEYIDISSNKFDNKQNN 287
+ M L+ I + +N+ N
Sbjct: 360 VFRMLANLQNISLQNNRLRQLPGN 383
>AB007876-1|BAA24846.2| 529|Homo sapiens KIAA0416 protein.
Length = 529
Score = 43.6 bits (98), Expect = 8e-04
Identities = 42/140 (30%), Positives = 70/140 (50%), Gaps = 6/140 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGV-VDWRWLLGPQITKTLK 536
L +L LDLS N++ L PE F + L LHL +N L V + W ++L+
Sbjct: 145 LINLQNLDLSFNQLSSLHPELFYGLRKLQTLHLRSNSLRTIPVRLFWD-------CRSLE 197
Query: 535 LLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSL 362
LDL++N+L L + L KL L N ++++ A R+S+L + N++ +L
Sbjct: 198 FLDLSTNRLRSLARNGFAGLIKLRELHLEHNQLTKINFAHFLRLSSLHTLFLQWNKISNL 257
Query: 361 PCSLMQC--RLEYIDISSNK 308
C + LE +D++ N+
Sbjct: 258 TCGMEWTWGTLEKLDLTGNE 277
Score = 35.9 bits (79), Expect = 0.16
Identities = 43/164 (26%), Positives = 68/164 (41%), Gaps = 6/164 (3%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 602
R LQ+L+L L + + L LDLS N + L F + L ELHL +NQ
Sbjct: 170 RKLQTLHLRSNSLRTIPVRLFWDCRSLEFLDLSTNRLRSLARNGFAGLIKLRELHLEHNQ 229
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAI-WKLEKLVTLKANDNMISRLPA 425
L + L +L L L NK+ +L + W L L N I +
Sbjct: 230 LTKINFAHFLRL------SSLHTLFLQWNKISNLTCGMEWTWGTLEKLDLTGNEIKAIDL 283
Query: 424 TI-GRISTLRYFTISSNELQSLPCSLMQC--RLEYIDISSNKFD 302
T+ + L+ + +N+L SL ++ L + +S N ++
Sbjct: 284 TVFETMPNLKILLMDNNKLNSLDSKILNSLRSLTTVGLSGNLWE 327
>BC126171-1|AAI26172.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/142 (26%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--KTLK 536
L+ L + L+NNE+E +P AN++ L LA N+ +V+ +L + ++L+
Sbjct: 97 LQSLREVKLNNNELETIPNLGPVSANITLLSLAGNR-----IVE---ILPEHLKEFQSLE 148
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRI-STLRYFTISSNELQSL 362
LDL+SN + L A L+ L L N N ++ + P + +TL ++ N + ++
Sbjct: 149 TLDLSSNNISELQTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAI 207
Query: 361 PCSLMQC-RLEYIDISSNKFDN 299
P + + +L++++++ NK N
Sbjct: 208 PPKMFKLPQLQHLELNRNKIKN 229
Score = 32.3 bits (70), Expect = 2.0
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 2/131 (1%)
Frame = -2
Query: 694 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
+LD S + +LP ++ L L++N+L L ++L+ + L +N
Sbjct: 57 LLDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHL------QSLREVKLNNN 108
Query: 514 KLGHLPKAIWKLEKLVTLK--ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC 341
+L +P + + +TL A + ++ LP + +L +SSN + L +
Sbjct: 109 ELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPAL 167
Query: 340 RLEYIDISSNK 308
+L+Y+ ++SN+
Sbjct: 168 QLKYLYLNSNR 178
>BC126169-1|AAI26170.1| 1119|Homo sapiens leucine-rich repeats and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/142 (26%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--KTLK 536
L+ L + L+NNE+E +P AN++ L LA N+ +V+ +L + ++L+
Sbjct: 97 LQSLREVKLNNNELETIPNLGPVSANITLLSLAGNR-----IVE---ILPEHLKEFQSLE 148
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRI-STLRYFTISSNELQSL 362
LDL+SN + L A L+ L L N N ++ + P + +TL ++ N + ++
Sbjct: 149 TLDLSSNNISELQTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAI 207
Query: 361 PCSLMQC-RLEYIDISSNKFDN 299
P + + +L++++++ NK N
Sbjct: 208 PPKMFKLPQLQHLELNRNKIKN 229
Score = 32.3 bits (70), Expect = 2.0
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 2/131 (1%)
Frame = -2
Query: 694 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
+LD S + +LP ++ L L++N+L L ++L+ + L +N
Sbjct: 57 LLDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHL------QSLREVKLNNN 108
Query: 514 KLGHLPKAIWKLEKLVTLK--ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC 341
+L +P + + +TL A + ++ LP + +L +SSN + L +
Sbjct: 109 ELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPAL 167
Query: 340 RLEYIDISSNK 308
+L+Y+ ++SN+
Sbjct: 168 QLKYLYLNSNR 178
>AY505340-1|AAR98629.1| 1119|Homo sapiens leucine-rich and
immunoglobulin-like domains 3 protein.
Length = 1119
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/142 (26%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--KTLK 536
L+ L + L+NNE+E +P AN++ L LA N+ +V+ +L + ++L+
Sbjct: 97 LQSLREVKLNNNELETIPNLGPVSANITLLSLAGNR-----IVE---ILPEHLKEFQSLE 148
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRI-STLRYFTISSNELQSL 362
LDL+SN + L A L+ L L N N ++ + P + +TL ++ N + ++
Sbjct: 149 TLDLSSNNISELQTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAI 207
Query: 361 PCSLMQC-RLEYIDISSNKFDN 299
P + + +L++++++ NK N
Sbjct: 208 PPKMFKLPQLQHLELNRNKIKN 229
Score = 32.3 bits (70), Expect = 2.0
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 2/131 (1%)
Frame = -2
Query: 694 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
+LD S + +LP ++ L L++N+L L ++L+ + L +N
Sbjct: 57 LLDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHL------QSLREVKLNNN 108
Query: 514 KLGHLPKAIWKLEKLVTLK--ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC 341
+L +P + + +TL A + ++ LP + +L +SSN + L +
Sbjct: 109 ELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPAL 167
Query: 340 RLEYIDISSNK 308
+L+Y+ ++SN+
Sbjct: 168 QLKYLYLNSNR 178
>AY358295-1|AAQ88662.1| 1059|Homo sapiens SAPS287 protein.
Length = 1059
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/142 (26%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--KTLK 536
L+ L + L+NNE+E +P AN++ L LA N+ +V+ +L + ++L+
Sbjct: 37 LQSLREVKLNNNELETIPNLGPVSANITLLSLAGNR-----IVE---ILPEHLKEFQSLE 88
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRI-STLRYFTISSNELQSL 362
LDL+SN + L A L+ L L N N ++ + P + +TL ++ N + ++
Sbjct: 89 TLDLSSNNISELQTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAI 147
Query: 361 PCSLMQC-RLEYIDISSNKFDN 299
P + + +L++++++ NK N
Sbjct: 148 PPKMFKLPQLQHLELNRNKIKN 169
>AY358290-1|AAQ88657.1| 713|Homo sapiens GAC1 protein.
Length = 713
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/141 (28%), Positives = 74/141 (52%), Gaps = 5/141 (3%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNF-RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQ 602
++L+SL +L RR + + L LDL+ N ++++ P +F M +L EL L NN
Sbjct: 237 QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGL-NNM 295
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSN-KLGHL-PKAIWKLEKLVTLKANDNMISRL- 431
+ + + + P++TK LD+T+N +L + P+A L ++ TL N+N +S L
Sbjct: 296 EELVSIDKFALVNLPELTK----LDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALH 351
Query: 430 PATIGRISTLRYFTISSNELQ 368
T+ + L+ + N ++
Sbjct: 352 QQTVESLPNLQEVGLHGNPIR 372
>AY358288-1|AAQ88655.1| 1119|Homo sapiens SAPS287 protein.
Length = 1119
Score = 43.2 bits (97), Expect = 0.001
Identities = 38/142 (26%), Positives = 75/142 (52%), Gaps = 5/142 (3%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQIT--KTLK 536
L+ L + L+NNE+E +P AN++ L LA N+ +V+ +L + ++L+
Sbjct: 97 LQSLREVKLNNNELETIPNLGPVSANITLLSLAGNR-----IVE---ILPEHLKEFQSLE 148
Query: 535 LLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRL-PATIGRI-STLRYFTISSNELQSL 362
LDL+SN + L A L+ L L N N ++ + P + +TL ++ N + ++
Sbjct: 149 TLDLSSNNISELQTAFPALQ-LKYLYLNSNRVTSMEPGYFDNLANTLLVLKLNRNRISAI 207
Query: 361 PCSLMQC-RLEYIDISSNKFDN 299
P + + +L++++++ NK N
Sbjct: 208 PPKMFKLPQLQHLELNRNKIKN 229
Score = 32.3 bits (70), Expect = 2.0
Identities = 29/131 (22%), Positives = 61/131 (46%), Gaps = 2/131 (1%)
Frame = -2
Query: 694 VLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDLTSN 515
+LD S + +LP ++ L L++N+L L ++L+ + L +N
Sbjct: 57 LLDCSRKRLARLPEPLPSW--VARLDLSHNRLSFIKASSMSHL------QSLREVKLNNN 108
Query: 514 KLGHLPKAIWKLEKLVTLK--ANDNMISRLPATIGRISTLRYFTISSNELQSLPCSLMQC 341
+L +P + + +TL A + ++ LP + +L +SSN + L +
Sbjct: 109 ELETIPN-LGPVSANITLLSLAGNRIVEILPEHLKEFQSLETLDLSSNNISELQTAFPAL 167
Query: 340 RLEYIDISSNK 308
+L+Y+ ++SN+
Sbjct: 168 QLKYLYLNSNR 178
>AL512306-1|CAI14096.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/141 (28%), Positives = 74/141 (52%), Gaps = 5/141 (3%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNF-RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQ 602
++L+SL +L RR + + L LDL+ N ++++ P +F M +L EL L NN
Sbjct: 237 QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGL-NNM 295
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSN-KLGHL-PKAIWKLEKLVTLKANDNMISRL- 431
+ + + + P++TK LD+T+N +L + P+A L ++ TL N+N +S L
Sbjct: 296 EELVSIDKFALVNLPELTK----LDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALH 351
Query: 430 PATIGRISTLRYFTISSNELQ 368
T+ + L+ + N ++
Sbjct: 352 QQTVESLPNLQEVGLHGNPIR 372
>AF030435-1|AAC39792.1| 713|Homo sapiens glioma amplified on
chromosome 1 protein protein.
Length = 713
Score = 43.2 bits (97), Expect = 0.001
Identities = 40/141 (28%), Positives = 74/141 (52%), Gaps = 5/141 (3%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNF-RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQ 602
++L+SL +L RR + + L LDL+ N ++++ P +F M +L EL L NN
Sbjct: 237 QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGL-NNM 295
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSN-KLGHL-PKAIWKLEKLVTLKANDNMISRL- 431
+ + + + P++TK LD+T+N +L + P+A L ++ TL N+N +S L
Sbjct: 296 EELVSIDKFALVNLPELTK----LDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSALH 351
Query: 430 PATIGRISTLRYFTISSNELQ 368
T+ + L+ + N ++
Sbjct: 352 QQTVESLPNLQEVGLHGNPIR 372
>BC070198-1|AAH70198.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 42.7 bits (96), Expect = 0.001
Identities = 50/158 (31%), Positives = 69/158 (43%), Gaps = 4/158 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG 596
LQ L+LS L + + L + L VLDL+ N + LPP F A L L L NQL
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLE 153
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
V V WL G K L LDL+ N+L LP P +
Sbjct: 154 VLEV---SWLHG---LKALGHLDLSGNRLRKLP----------------------PGLLA 185
Query: 415 RISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNK 308
+ LR + N+L++LP L++ +LE + + NK
Sbjct: 186 NFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNK 223
Score = 37.9 bits (84), Expect = 0.041
Identities = 44/122 (36%), Positives = 56/122 (45%), Gaps = 5/122 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMAN---LSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
LK L LDLS N + KLPP G +AN L L L NQL + L GP L
Sbjct: 163 LKALGHLDLSGNRLRKLPP--GLLANFTLLRTLDLGENQL---ETLPPDLLRGP---LQL 214
Query: 538 KLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPA-TIGRISTLRYFTISSNELQS 365
+ L L NKL L K + L L N N ++R+ A + L +S+N L S
Sbjct: 215 ERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLAS 274
Query: 364 LP 359
+P
Sbjct: 275 VP 276
>AF403428-1|AAK95527.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 42.7 bits (96), Expect = 0.001
Identities = 50/158 (31%), Positives = 69/158 (43%), Gaps = 4/158 (2%)
Frame = -2
Query: 769 LQSLYLSGLKLCNFRRDILL-LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLG 596
LQ L+LS L + + L + L VLDL+ N + LPP F A L L L NQL
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNALTGLPPGLFQASATLDTLVLKENQLE 153
Query: 595 VRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIG 416
V V WL G K L LDL+ N+L LP P +
Sbjct: 154 VLEV---SWLHG---LKALGHLDLSGNRLRKLP----------------------PGLLA 185
Query: 415 RISTLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNK 308
+ LR + N+L++LP L++ +LE + + NK
Sbjct: 186 NFTLLRTLDLGENQLETLPPDLLRGPLQLERLHLEGNK 223
Score = 37.9 bits (84), Expect = 0.041
Identities = 44/122 (36%), Positives = 56/122 (45%), Gaps = 5/122 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMAN---LSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
LK L LDLS N + KLPP G +AN L L L NQL + L GP L
Sbjct: 163 LKALGHLDLSGNRLRKLPP--GLLANFTLLRTLDLGENQL---ETLPPDLLRGP---LQL 214
Query: 538 KLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPA-TIGRISTLRYFTISSNELQS 365
+ L L NKL L K + L L N N ++R+ A + L +S+N L S
Sbjct: 215 ERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLAS 274
Query: 364 LP 359
+P
Sbjct: 275 VP 276
>X57436-1|CAA40684.1| 440|Homo sapiens oligodentrocyte-myelin
glycoprotein protein.
Length = 440
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/159 (25%), Positives = 79/159 (49%), Gaps = 21/159 (13%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVD--WRW------------- 569
+L LD+SNN +E LP R +L + ANN + + D ++W
Sbjct: 79 NLRTLDISNNRLESLPAHLPR--SLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLE 136
Query: 568 --LLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
+L ++L++L+L+SNKL +P + +V L +N+++ LP T+ ++ L +
Sbjct: 137 KVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDL-SNNSLTQILPGTLINLTNLTH 195
Query: 394 FTISSNELQSLPCSLMQ--CRLEYIDISSNKF--DNKQN 290
+ +N+ +P +L+ I + +N++ D+KQN
Sbjct: 196 LYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQN 234
>X51694-1|CAA35991.1| 433|Homo sapiens oligodendrocyte-myelin
glycoprotein protein.
Length = 433
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/159 (25%), Positives = 79/159 (49%), Gaps = 21/159 (13%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVD--WRW------------- 569
+L LD+SNN +E LP R +L + ANN + + D ++W
Sbjct: 72 NLRTLDISNNRLESLPAHLPR--SLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLE 129
Query: 568 --LLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
+L ++L++L+L+SNKL +P + +V L +N+++ LP T+ ++ L +
Sbjct: 130 KVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDL-SNNSLTQILPGTLINLTNLTH 188
Query: 394 FTISSNELQSLPCSLMQ--CRLEYIDISSNKF--DNKQN 290
+ +N+ +P +L+ I + +N++ D+KQN
Sbjct: 189 LYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQN 227
>M63623-1|AAA59970.1| 440|Homo sapiens oligodendrocyte-myelin
glycoprotein protein.
Length = 440
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/159 (25%), Positives = 79/159 (49%), Gaps = 21/159 (13%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVD--WRW------------- 569
+L LD+SNN +E LP R +L + ANN + + D ++W
Sbjct: 79 NLRTLDISNNRLESLPAHLPR--SLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLE 136
Query: 568 --LLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
+L ++L++L+L+SNKL +P + +V L +N+++ LP T+ ++ L +
Sbjct: 137 KVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDL-SNNSLTQILPGTLINLTNLTH 195
Query: 394 FTISSNELQSLPCSLMQ--CRLEYIDISSNKF--DNKQN 290
+ +N+ +P +L+ I + +N++ D+KQN
Sbjct: 196 LYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQN 234
>BC117190-1|AAI17191.1| 1529|Homo sapiens slit homolog 2 (Drosophila)
protein.
Length = 1529
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/96 (33%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 602
PR + LYL G + +++ KHL ++DLSNN I L + F M L L L+ N+
Sbjct: 753 PRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 812
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 494
L + R G K+L+LL L N + +P+
Sbjct: 813 L---RCIPPRTFDG---LKSLRLLSLHGNDISVVPE 842
Score = 31.1 bits (67), Expect = 4.7
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 2/129 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
K L +DLSNN+I +L P+ F + +L+ L L N++ + L +L+LL
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLF------SLQLL 377
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L +NK+ L A L L L DN + + G S LR I + L P
Sbjct: 378 LLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK--GTFSPLR--AIQTMHLAQNP-F 432
Query: 352 LMQCRLEYI 326
+ C L+++
Sbjct: 433 ICDCHLKWL 441
>BC101065-1|AAI01066.1| 581|Homo sapiens LRRC15 protein protein.
Length = 581
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/144 (29%), Positives = 66/144 (45%), Gaps = 5/144 (3%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
+L L LSNN I +LPP F ++ L+ L L N L + GP L+ L
Sbjct: 246 NLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELS----PGIFGPM--PNLRELW 299
Query: 526 LTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCS 353
L N + LP ++ L +L L + N IS + P ++ LR ++ +N LQ L +
Sbjct: 300 LYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGN 359
Query: 352 L--MQCRLEYIDISSNKFDNKQNN 287
+ M L+ I + +N+ N
Sbjct: 360 VFRMLANLQNISLQNNRLRQLPGN 383
>BC101064-1|AAI01065.1| 581|Homo sapiens leucine rich repeat
containing 15 protein.
Length = 581
Score = 42.3 bits (95), Expect = 0.002
Identities = 42/144 (29%), Positives = 66/144 (45%), Gaps = 5/144 (3%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLD 527
+L L LSNN I +LPP F ++ L+ L L N L + GP L+ L
Sbjct: 246 NLQRLYLSNNHISQLPPSVFMQLPQLNRLTLFGNSLKELS----PGIFGPM--PNLRELW 299
Query: 526 LTSNKLGHLPKAIW-KLEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLPCS 353
L N + LP ++ L +L L + N IS + P ++ LR ++ +N LQ L +
Sbjct: 300 LYDNHISSLPDNVFSNLRQLQVLILSRNQISFISPGAFNGLTELRELSLHTNALQDLDGN 359
Query: 352 L--MQCRLEYIDISSNKFDNKQNN 287
+ M L+ I + +N+ N
Sbjct: 360 VFRMLANLQNISLQNNRLRQLPGN 383
>BC068541-1|AAH68541.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/119 (31%), Positives = 65/119 (54%), Gaps = 4/119 (3%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNF-RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQ 602
++L+SL +L RR + + L LDL+ N ++++ P +F M +L EL L NN
Sbjct: 237 QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGL-NNM 295
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSN-KLGHL-PKAIWKLEKLVTLKANDNMISRL 431
+ + + + P++TK LD+T+N +L + P+A L ++ TL N+N +S L
Sbjct: 296 EELVSIDKFALVNLPELTK----LDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSAL 350
>BC042334-1|AAH42334.2| 545|Homo sapiens carboxypeptidase N,
polypeptide 2 protein.
Length = 545
Score = 42.3 bits (95), Expect = 0.002
Identities = 39/120 (32%), Positives = 56/120 (46%), Gaps = 3/120 (2%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKL 533
L +L L L N + LP F L L L +NQL + L L+
Sbjct: 264 LGNLTFLSLQWNMLRVLPAGLFAHTPCLVGLSLTHNQLETVAEGTFAHL------SNLRS 317
Query: 532 LDLTSNKLGHLPKAIWK-LEKLVTLKANDNMISRL-PATIGRISTLRYFTISSNELQSLP 359
L L+ N + HLP I++ LE+LV L N ++ L PA +S L ++S N+L +LP
Sbjct: 318 LMLSYNAITHLPAGIFRDLEELVKLYLGSNNLTALHPALFQNLSKLELLSLSKNQLTTLP 377
>BC034047-1|AAH34047.1| 713|Homo sapiens leucine rich repeat
neuronal 2 protein.
Length = 713
Score = 42.3 bits (95), Expect = 0.002
Identities = 37/119 (31%), Positives = 65/119 (54%), Gaps = 4/119 (3%)
Frame = -2
Query: 775 RTLQSLYLSGLKLCNF-RRDILLLKHLAVLDLSNNEIEKLPP-EFGRMANLSELHLANNQ 602
++L+SL +L RR + + L LDL+ N ++++ P +F M +L EL L NN
Sbjct: 237 QSLESLSFYDNQLARVPRRALEQVPGLKFLDLNKNPLQRVGPGDFANMLHLKELGL-NNM 295
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSN-KLGHL-PKAIWKLEKLVTLKANDNMISRL 431
+ + + + P++TK LD+T+N +L + P+A L ++ TL N+N +S L
Sbjct: 296 EELVSIDKFALVNLPELTK----LDITNNPRLSFIHPRAFHHLPQMETLMLNNNALSAL 350
>BC018050-1|AAH18050.1| 440|Homo sapiens oligodendrocyte myelin
glycoprotein protein.
Length = 440
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/159 (25%), Positives = 79/159 (49%), Gaps = 21/159 (13%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVD--WRW------------- 569
+L LD+SNN +E LP R +L + ANN + + D ++W
Sbjct: 79 NLRTLDISNNRLESLPAHLPR--SLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLE 136
Query: 568 --LLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
+L ++L++L+L+SNKL +P + +V L +N+++ LP T+ ++ L +
Sbjct: 137 KVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDL-SNNSLTQILPGTLINLTNLTH 195
Query: 394 FTISSNELQSLPCSLMQ--CRLEYIDISSNKF--DNKQN 290
+ +N+ +P +L+ I + +N++ D+KQN
Sbjct: 196 LYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQN 234
>AK222663-1|BAD96383.1| 440|Homo sapiens oligodendrocyte myelin
glycoprotein variant protein.
Length = 440
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/159 (25%), Positives = 79/159 (49%), Gaps = 21/159 (13%)
Frame = -2
Query: 703 HLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLGVRGVVD--WRW------------- 569
+L LD+SNN +E LP R +L + ANN + + D ++W
Sbjct: 79 NLRTLDISNNRLESLPAHLPR--SLWNMSAANNNIKLLDKSDTAYQWNLKYLDVSKNMLE 136
Query: 568 --LLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRY 395
+L ++L++L+L+SNKL +P + +V L +N+++ LP T+ ++ L +
Sbjct: 137 KVVLIKNTLRSLEVLNLSSNKLWTVPTNMPSKLHIVDL-SNNSLTQILPGTLINLTNLTH 195
Query: 394 FTISSNELQSLPCSLMQ--CRLEYIDISSNKF--DNKQN 290
+ +N+ +P +L+ I + +N++ D+KQN
Sbjct: 196 LYLHNNKFTFIPDQSFDQLFQLQEITLYNNRWSCDHKQN 234
>AF133270-1|AAD25539.1| 1525|Homo sapiens SLIT2 protein.
Length = 1525
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/96 (33%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 602
PR + LYL G + +++ KHL ++DLSNN I L + F M L L L+ N+
Sbjct: 749 PRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 808
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 494
L + R G K+L+LL L N + +P+
Sbjct: 809 L---RCIPPRTFDG---LKSLRLLSLHGNDISVVPE 838
Score = 31.1 bits (67), Expect = 4.7
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 2/129 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
K L +DLSNN+I +L P+ F + +L+ L L N++ + L +L+LL
Sbjct: 328 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLF------SLQLL 381
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L +NK+ L A L L L DN + + G S LR I + L P
Sbjct: 382 LLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK--GTFSPLR--AIQTMHLAQNP-F 436
Query: 352 LMQCRLEYI 326
+ C L+++
Sbjct: 437 ICDCHLKWL 445
>AF055585-1|AAD04309.1| 1521|Homo sapiens neurogenic extracellular
slit protein Slit2 protein.
Length = 1521
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/96 (33%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 602
PR + LYL G + +++ KHL ++DLSNN I L + F M L L L+ N+
Sbjct: 745 PRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 804
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 494
L + R G K+L+LL L N + +P+
Sbjct: 805 L---RCIPPRTFDG---LKSLRLLSLHGNDISVVPE 834
Score = 31.1 bits (67), Expect = 4.7
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 2/129 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
K L +DLSNN+I +L P+ F + +L+ L L N++ + L +L+LL
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLF------SLQLL 377
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L +NK+ L A L L L DN + + G S LR I + L P
Sbjct: 378 LLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK--GTFSPLR--AIQTMHLAQNP-F 432
Query: 352 LMQCRLEYI 326
+ C L+++
Sbjct: 433 ICDCHLKWL 441
>AB017168-1|BAA35185.1| 1529|Homo sapiens Slit-2 protein protein.
Length = 1529
Score = 42.3 bits (95), Expect = 0.002
Identities = 32/96 (33%), Positives = 48/96 (50%), Gaps = 1/96 (1%)
Frame = -2
Query: 778 PRTLQSLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQ 602
PR + LYL G + +++ KHL ++DLSNN I L + F M L L L+ N+
Sbjct: 753 PRDVTELYLDGNQFTLVPKELSNYKHLTLIDLSNNRISTLSNQSFSNMTQLLTLILSYNR 812
Query: 601 LGVRGVVDWRWLLGPQITKTLKLLDLTSNKLGHLPK 494
L + R G K+L+LL L N + +P+
Sbjct: 813 L---RCIPPRTFDG---LKSLRLLSLHGNDISVVPE 842
Score = 31.1 bits (67), Expect = 4.7
Identities = 38/129 (29%), Positives = 59/129 (45%), Gaps = 2/129 (1%)
Frame = -2
Query: 706 KHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLL 530
K L +DLSNN+I +L P+ F + +L+ L L N++ + L +L+LL
Sbjct: 324 KKLRRIDLSNNQISELAPDAFQGLRSLNSLVLYGNKITELPKSLFEGLF------SLQLL 377
Query: 529 DLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQSLPCS 353
L +NK+ L A L L L DN + + G S LR I + L P
Sbjct: 378 LLNANKINCLRVDAFQDLHNLNLLSLYDNKLQTIAK--GTFSPLR--AIQTMHLAQNP-F 432
Query: 352 LMQCRLEYI 326
+ C L+++
Sbjct: 433 ICDCHLKWL 441
>BC101073-1|AAI01074.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLP-PEFGRMANLSELHLANNQLGVRG 587
SL +GL + + D L + + L N I + F + L +LH+ +N L +
Sbjct: 70 SLLNNGLTMLH-TNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 586 VVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ L + L+ L +N + + P A KL +L L NDN I LP I R
Sbjct: 129 EDTFHGL------ENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRF 182
Query: 409 STLRYFTISSNELQSLP 359
L + + N+LQ+LP
Sbjct: 183 VPLTHLDLRGNQLQTLP 199
>BC101072-1|AAI01073.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLP-PEFGRMANLSELHLANNQLGVRG 587
SL +GL + + D L + + L N I + F + L +LH+ +N L +
Sbjct: 70 SLLNNGLTMLH-TNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 586 VVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ L + L+ L +N + + P A KL +L L NDN I LP I R
Sbjct: 129 EDTFHGL------ENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRF 182
Query: 409 STLRYFTISSNELQSLP 359
L + + N+LQ+LP
Sbjct: 183 VPLTHLDLRGNQLQTLP 199
>BC101071-1|AAI01072.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLP-PEFGRMANLSELHLANNQLGVRG 587
SL +GL + + D L + + L N I + F + L +LH+ +N L +
Sbjct: 70 SLLNNGLTMLH-TNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 586 VVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ L + L+ L +N + + P A KL +L L NDN I LP I R
Sbjct: 129 EDTFHGL------ENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRF 182
Query: 409 STLRYFTISSNELQSLP 359
L + + N+LQ+LP
Sbjct: 183 VPLTHLDLRGNQLQTLP 199
>BC101070-1|AAI01071.1| 841|Homo sapiens SLIT and NTRK-like family,
member 6 protein.
Length = 841
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLP-PEFGRMANLSELHLANNQLGVRG 587
SL +GL + + D L + + L N I + F + L +LH+ +N L +
Sbjct: 70 SLLNNGLTMLH-TNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 128
Query: 586 VVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ L + L+ L +N + + P A KL +L L NDN I LP I R
Sbjct: 129 EDTFHGL------ENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRF 182
Query: 409 STLRYFTISSNELQSLP 359
L + + N+LQ+LP
Sbjct: 183 VPLTHLDLRGNQLQTLP 199
>AK026427-1|BAB15480.1| 440|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22774 fis, clone KAIA1575. ).
Length = 440
Score = 41.9 bits (94), Expect = 0.002
Identities = 39/137 (28%), Positives = 61/137 (44%), Gaps = 2/137 (1%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLP-PEFGRMANLSELHLANNQLGVRG 587
SL +GL + + D L + + L N I + F + L +LH+ +N L +
Sbjct: 27 SLLNNGLTMLH-TNDFSGLTNAISIHLGFNNIADIEIGAFNGLGLLKQLHINHNSLEILK 85
Query: 586 VVDWRWLLGPQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPATIGRI 410
+ L + L+ L +N + + P A KL +L L NDN I LP I R
Sbjct: 86 EDTFHGL------ENLEFLQADNNFITVIEPSAFSKLNRLKVLILNDNAIESLPPNIFRF 139
Query: 409 STLRYFTISSNELQSLP 359
L + + N+LQ+LP
Sbjct: 140 VPLTHLDLRGNQLQTLP 156
>BC034389-1|AAH34389.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein 1 protein.
Length = 347
Score = 41.5 bits (93), Expect = 0.003
Identities = 42/136 (30%), Positives = 66/136 (48%), Gaps = 5/136 (3%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPEFGR-MANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 524
L L LS+N +E L PEF R + L L L N L G+ + Q + TL L L
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNAL--TGLPSGLF----QASATLDTLVL 147
Query: 523 TSNKLGHLPKA-IWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLPCSL 350
N+L L + + L+ L L + N + +LP + + LR + N+L++LP L
Sbjct: 148 KENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDL 207
Query: 349 MQ--CRLEYIDISSNK 308
++ +LE + + NK
Sbjct: 208 LRGPLQLERLHLEGNK 223
Score = 37.9 bits (84), Expect = 0.041
Identities = 44/122 (36%), Positives = 56/122 (45%), Gaps = 5/122 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMAN---LSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
LK L LDLS N + KLPP G +AN L L L NQL + L GP L
Sbjct: 163 LKALGHLDLSGNRLRKLPP--GLLANFTLLRTLDLGENQL---ETLPPDLLRGP---LQL 214
Query: 538 KLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPA-TIGRISTLRYFTISSNELQS 365
+ L L NKL L K + L L N N ++R+ A + L +S+N L S
Sbjct: 215 ERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLAS 274
Query: 364 LP 359
+P
Sbjct: 275 VP 276
>AY358733-1|AAQ89095.1| 622|Homo sapiens CGLQ1891 protein.
Length = 622
Score = 41.5 bits (93), Expect = 0.003
Identities = 47/182 (25%), Positives = 92/182 (50%), Gaps = 24/182 (13%)
Frame = -2
Query: 772 TLQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQL 599
+L +LYL + + + + L+HL L L+NN I++L P F + NL L+L NQ+
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 598 GV--RGV------VDWRWLLGPQIT----------KTLKLLDLTSNKLGHLPKAIWK-LE 476
RGV V + L ++T L++LDL++N + + ++ ++ LE
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLE 204
Query: 475 KLVTLKANDNMISRLPATIGRI-STLRYFTISSNELQSL-PCSLM-QCRLEYIDISSNKF 305
L L N ++++P+ + +LR ++S N ++++ P + LEY+ + +++
Sbjct: 205 NLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRI 264
Query: 304 DN 299
N
Sbjct: 265 RN 266
>AY280614-1|AAP36706.1| 622|Homo sapiens synleurin protein.
Length = 622
Score = 41.5 bits (93), Expect = 0.003
Identities = 47/182 (25%), Positives = 92/182 (50%), Gaps = 24/182 (13%)
Frame = -2
Query: 772 TLQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQL 599
+L +LYL + + + + L+HL L L+NN I++L P F + NL L+L NQ+
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 598 GV--RGV------VDWRWLLGPQIT----------KTLKLLDLTSNKLGHLPKAIWK-LE 476
RGV V + L ++T L++LDL++N + + ++ ++ LE
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLE 204
Query: 475 KLVTLKANDNMISRLPATIGRI-STLRYFTISSNELQSL-PCSLM-QCRLEYIDISSNKF 305
L L N ++++P+ + +LR ++S N ++++ P + LEY+ + +++
Sbjct: 205 NLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRI 264
Query: 304 DN 299
N
Sbjct: 265 RN 266
>AK123022-1|BAC85517.1| 622|Homo sapiens protein ( Homo sapiens
cDNA FLJ41026 fis, clone BRAMY2004771, weakly similar
to CHONDROADHERIN PRECURSOR. ).
Length = 622
Score = 41.5 bits (93), Expect = 0.003
Identities = 47/182 (25%), Positives = 92/182 (50%), Gaps = 24/182 (13%)
Frame = -2
Query: 772 TLQSLYLSGLKLCN-FRRDILLLKHLAVLDLSNNEIEKLPPE-FGRMANLSELHLANNQL 599
+L +LYL + + + + L+HL L L+NN I++L P F + NL L+L NQ+
Sbjct: 85 SLVALYLDNSNILYVYPKAFVQLRHLYFLFLNNNFIKRLDPGIFKGLLNLRNLYLQYNQV 144
Query: 598 GV--RGV------VDWRWLLGPQIT----------KTLKLLDLTSNKLGHLPKAIWK-LE 476
RGV V + L ++T L++LDL++N + + ++ ++ LE
Sbjct: 145 SFVPRGVFNDLVSVQYLNLQRNRLTVLGSGTFVGMVALRILDLSNNNILRISESGFQHLE 204
Query: 475 KLVTLKANDNMISRLPATIGRI-STLRYFTISSNELQSL-PCSLM-QCRLEYIDISSNKF 305
L L N ++++P+ + +LR ++S N ++++ P + LEY+ + +++
Sbjct: 205 NLACLYLGSNNLTKVPSNAFEVLKSLRRLSLSHNPIEAIQPFAFKGLANLEYLLLKNSRI 264
Query: 304 DN 299
N
Sbjct: 265 RN 266
>AB073607-1|BAD38644.1| 347|Homo sapiens leucine-rich
alpha-2-glycoprotein protein.
Length = 347
Score = 41.5 bits (93), Expect = 0.003
Identities = 42/136 (30%), Positives = 66/136 (48%), Gaps = 5/136 (3%)
Frame = -2
Query: 700 LAVLDLSNNEIEKLPPEFGR-MANLSELHLANNQLGVRGVVDWRWLLGPQITKTLKLLDL 524
L L LS+N +E L PEF R + L L L N L G+ + Q + TL L L
Sbjct: 94 LQELHLSSNGLESLSPEFLRPVPQLRVLDLTRNAL--TGLPSGLF----QASATLDTLVL 147
Query: 523 TSNKLGHLPKA-IWKLEKLVTLKANDNMISRLP-ATIGRISTLRYFTISSNELQSLPCSL 350
N+L L + + L+ L L + N + +LP + + LR + N+L++LP L
Sbjct: 148 KENQLEVLEVSWLHGLKALGHLDLSGNRLRKLPPGLLANFTLLRTLDLGENQLETLPPDL 207
Query: 349 MQ--CRLEYIDISSNK 308
++ +LE + + NK
Sbjct: 208 LRGPLQLERLHLEGNK 223
Score = 37.9 bits (84), Expect = 0.041
Identities = 44/122 (36%), Positives = 56/122 (45%), Gaps = 5/122 (4%)
Frame = -2
Query: 709 LKHLAVLDLSNNEIEKLPPEFGRMAN---LSELHLANNQLGVRGVVDWRWLLGPQITKTL 539
LK L LDLS N + KLPP G +AN L L L NQL + L GP L
Sbjct: 163 LKALGHLDLSGNRLRKLPP--GLLANFTLLRTLDLGENQL---ETLPPDLLRGP---LQL 214
Query: 538 KLLDLTSNKLGHLPK-AIWKLEKLVTLKANDNMISRLPA-TIGRISTLRYFTISSNELQS 365
+ L L NKL L K + L L N N ++R+ A + L +S+N L S
Sbjct: 215 ERLHLEGNKLQVLGKDLLLPQPDLRYLFLNGNKLARVAAGAFQGLRQLDMLDLSNNSLAS 274
Query: 364 LP 359
+P
Sbjct: 275 VP 276
>BC030276-1|AAH30276.1| 529|Homo sapiens LOC220416 protein protein.
Length = 529
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
K L++L L +N + +P I +LE L N+I+ LP + +S L +S NEL
Sbjct: 368 KNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELT 427
Query: 367 SLPCSLMQCR-LEYIDISSNK 308
+P + + R LE + + N+
Sbjct: 428 FIPNEIQKLRSLEKLTVDGNE 448
>AL139801-5|CAM14704.1| 506|Homo sapiens similar to Leucine-rich
repeat protein SHOC-2 (Ras-binding protein Sur-8)
protein.
Length = 506
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
K L++L L +N + +P I +LE L N+I+ LP + +S L +S NEL
Sbjct: 368 KNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELT 427
Query: 367 SLPCSLMQCR-LEYIDISSNK 308
+P + + R LE + + N+
Sbjct: 428 FIPNEIQKLRSLEKLTVDGNE 448
>AL137141-1|CAI12166.2| 506|Homo sapiens similar to Leucine-rich
repeat protein SHOC-2 (Ras-binding protein Sur-8)
protein.
Length = 506
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 1/81 (1%)
Frame = -2
Query: 547 KTLKLLDLTSNKLGHLPKAIWKLEKLVTLKANDNMISRLPATIGRISTLRYFTISSNELQ 368
K L++L L +N + +P I +LE L N+I+ LP + +S L +S NEL
Sbjct: 368 KNLQILKLRNNPIKEIPSEIQQLEFLRIFTIAFNLITVLPIGLFSLSYLEELDVSYNELT 427
Query: 367 SLPCSLMQCR-LEYIDISSNK 308
+P + + R LE + + N+
Sbjct: 428 FIPNEIQKLRSLEKLTVDGNE 448
>AK130975-1|BAC85472.1| 209|Homo sapiens protein ( Homo sapiens
cDNA FLJ27465 fis, clone MPC08423. ).
Length = 209
Score = 41.1 bits (92), Expect = 0.004
Identities = 30/86 (34%), Positives = 47/86 (54%), Gaps = 2/86 (2%)
Frame = -2
Query: 691 LDLSNNEIEKLPPEFG-RMANLSELHLANNQLG-VRGVVDWRWLLGPQITKTLKLLDLTS 518
LDLS N + LP + NL +L+L++N LG + GV ++ ++ + +D++S
Sbjct: 128 LDLSANCLATLPSVIPWGLINLRKLNLSDNHLGELPGVQSSDEIICSRLLE----IDISS 183
Query: 517 NKLGHLPKAIWKLEKLVTLKANDNMI 440
NKL HLP L KL L A+ N +
Sbjct: 184 NKLSHLPPGFLHLSKLQKLTASKNCL 209
Score = 30.3 bits (65), Expect = 8.1
Identities = 13/41 (31%), Positives = 24/41 (58%)
Frame = -2
Query: 721 DILLLKHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQL 599
D ++ L +D+S+N++ LPP F ++ L +L + N L
Sbjct: 169 DEIICSRLLEIDISSNKLSHLPPGFLHLSKLQKLTASKNCL 209
>AB209379-1|BAD92616.1| 245|Homo sapiens hypothetical protein
DKFZp434K1815 variant protein.
Length = 245
Score = 41.1 bits (92), Expect = 0.004
Identities = 27/56 (48%), Positives = 33/56 (58%), Gaps = 3/56 (5%)
Frame = -2
Query: 754 LSGLKLCNFRRDILLL---KHLAVLDLSNNEIEKLPPEFGRMANLSELHLANNQLG 596
LSGL+L + D LL L LDLSNN +E LP G +++L L ANNQLG
Sbjct: 6 LSGLELLSEHLDPKLLCRLTQLQELDLSNNHLETLPDNLG-LSHLRVLRCANNQLG 60
>D86983-1|BAA13219.1| 1496|Homo sapiens KIAA0230 protein.
Length = 1496
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Frame = -2
Query: 559 PQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPA-TIGRISTLRYFTI 386
P + +LDL N++ + P A +L L TL N+N I R+P+ + L+Y +
Sbjct: 75 PAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYL 134
Query: 385 SSNELQSL 362
NE+QS+
Sbjct: 135 YKNEIQSI 142
>BC098579-1|AAH98579.1| 722|Homo sapiens PXDN protein protein.
Length = 722
Score = 40.7 bits (91), Expect = 0.006
Identities = 22/68 (32%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Frame = -2
Query: 559 PQITKTLKLLDLTSNKLGHL-PKAIWKLEKLVTLKANDNMISRLPA-TIGRISTLRYFTI 386
P + +LDL N++ + P A +L L TL N+N I R+P+ + L+Y +
Sbjct: 53 PAVAPQTSILDLRFNRIREIQPGAFRRLRNLNTLLLNNNQIKRIPSGAFEDLENLKYLYL 112
Query: 385 SSNELQSL 362
NE+QS+
Sbjct: 113 YKNEIQSI 120
>BC033651-1|AAH33651.1| 1049|Homo sapiens toll-like receptor 7
protein.
Length = 1049
Score = 40.7 bits (91), Expect = 0.006
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 6/128 (4%)
Frame = -2
Query: 649 FGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP-KAIWKL 479
F + L EL ++ N L GV D + LK L L N L K + L
Sbjct: 646 FKNLLKLEELDISKNSLSFLPSGVFDG-------MPPNLKNLSLAKNGLKSFSWKKLQCL 698
Query: 478 EKLVTLKANDNMISRLPATIGRIS-TLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNK 308
+ L TL + N ++ +P + S +L+ + +N+++SL +Q +L Y+D+SSNK
Sbjct: 699 KNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNK 758
Query: 307 FDNKQNNS 284
Q S
Sbjct: 759 IQMIQKTS 766
Score = 40.3 bits (90), Expect = 0.008
Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 1/103 (0%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMA-NLSELHLANNQLGVRG 587
SL +GLK ++++ + LK+L LDLS+N++ +P + +L L L NNQ +R
Sbjct: 681 SLAKNGLKSFSWKK-LQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQ--IRS 737
Query: 586 VVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+ ++ L Q L+ LDL+SNK+ + K + L LK
Sbjct: 738 LT--KYFL--QDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLK 776
>AY358292-1|AAQ88659.1| 1049|Homo sapiens TLR7 protein.
Length = 1049
Score = 40.7 bits (91), Expect = 0.006
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 6/128 (4%)
Frame = -2
Query: 649 FGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP-KAIWKL 479
F + L EL ++ N L GV D + LK L L N L K + L
Sbjct: 646 FKNLLKLEELDISKNSLSFLPSGVFDG-------MPPNLKNLSLAKNGLKSFSWKKLQCL 698
Query: 478 EKLVTLKANDNMISRLPATIGRIS-TLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNK 308
+ L TL + N ++ +P + S +L+ + +N+++SL +Q +L Y+D+SSNK
Sbjct: 699 KNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNK 758
Query: 307 FDNKQNNS 284
Q S
Sbjct: 759 IQMIQKTS 766
Score = 40.3 bits (90), Expect = 0.008
Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 1/103 (0%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMA-NLSELHLANNQLGVRG 587
SL +GLK ++++ + LK+L LDLS+N++ +P + +L L L NNQ +R
Sbjct: 681 SLAKNGLKSFSWKK-LQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQ--IRS 737
Query: 586 VVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+ ++ L Q L+ LDL+SNK+ + K + L LK
Sbjct: 738 LT--KYFL--QDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLK 776
>AF240467-1|AAF60188.1| 1049|Homo sapiens toll-like receptor 7
protein.
Length = 1049
Score = 40.7 bits (91), Expect = 0.006
Identities = 37/128 (28%), Positives = 59/128 (46%), Gaps = 6/128 (4%)
Frame = -2
Query: 649 FGRMANLSELHLANNQLGV--RGVVDWRWLLGPQITKTLKLLDLTSNKLGHLP-KAIWKL 479
F + L EL ++ N L GV D + LK L L N L K + L
Sbjct: 646 FKNLLKLEELDISKNSLSFLPSGVFDG-------MPPNLKNLSLAKNGLKSFSWKKLQCL 698
Query: 478 EKLVTLKANDNMISRLPATIGRIS-TLRYFTISSNELQSLPCSLMQ--CRLEYIDISSNK 308
+ L TL + N ++ +P + S +L+ + +N+++SL +Q +L Y+D+SSNK
Sbjct: 699 KNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQIRSLTKYFLQDAFQLRYLDLSSNK 758
Query: 307 FDNKQNNS 284
Q S
Sbjct: 759 IQMIQKTS 766
Score = 40.3 bits (90), Expect = 0.008
Identities = 34/103 (33%), Positives = 56/103 (54%), Gaps = 1/103 (0%)
Frame = -2
Query: 763 SLYLSGLKLCNFRRDILLLKHLAVLDLSNNEIEKLPPEFGRMA-NLSELHLANNQLGVRG 587
SL +GLK ++++ + LK+L LDLS+N++ +P + +L L L NNQ +R
Sbjct: 681 SLAKNGLKSFSWKK-LQCLKNLETLDLSHNQLTTVPERLSNCSRSLKNLILKNNQ--IRS 737
Query: 586 VVDWRWLLGPQITKTLKLLDLTSNKLGHLPKAIWKLEKLVTLK 458
+ ++ L Q L+ LDL+SNK+ + K + L LK
Sbjct: 738 LT--KYFL--QDAFQLRYLDLSSNKIQMIQKTSFPENVLNNLK 776
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 106,760,012
Number of Sequences: 237096
Number of extensions: 2137852
Number of successful extensions: 5869
Number of sequences better than 10.0: 457
Number of HSP's better than 10.0 without gapping: 4411
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5239
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9478778060
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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