Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV19n20r
(814 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 106 1e-22
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 105 3e-22
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 105 3e-22
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 105 3e-22
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 105 3e-22
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 103 6e-22
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 103 6e-22
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 103 6e-22
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 103 6e-22
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 103 1e-21
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 103 1e-21
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 103 1e-21
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 103 1e-21
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 102 2e-21
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 101 2e-21
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 101 2e-21
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 101 2e-21
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 100 5e-21
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 99 9e-21
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 99 9e-21
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 87 7e-17
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 87 7e-17
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 87 7e-17
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 87 7e-17
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 87 7e-17
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 87 7e-17
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 87 7e-17
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 87 7e-17
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 85 2e-16
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 85 2e-16
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 85 2e-16
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 85 2e-16
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 85 2e-16
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 85 2e-16
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 85 2e-16
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 85 2e-16
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 84 5e-16
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 84 5e-16
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 83 9e-16
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 83 9e-16
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 83 1e-15
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 83 1e-15
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 83 1e-15
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 83 1e-15
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 82 3e-15
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 81 6e-15
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 81 6e-15
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 80 8e-15
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 80 1e-14
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 79 1e-14
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 79 1e-14
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 79 2e-14
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 79 2e-14
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 77 8e-14
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 77 8e-14
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 77 8e-14
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 77 8e-14
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 76 1e-13
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 75 2e-13
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 73 9e-13
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 73 2e-12
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 73 2e-12
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 73 2e-12
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 73 2e-12
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 72 3e-12
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 72 3e-12
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 72 3e-12
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 70 9e-12
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 70 1e-11
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 70 1e-11
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 70 1e-11
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 67 6e-11
AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 67 8e-11
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 66 1e-10
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 66 1e-10
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 66 1e-10
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 66 1e-10
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 66 1e-10
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 66 1e-10
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 66 1e-10
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 66 1e-10
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 66 1e-10
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 65 2e-10
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 65 2e-10
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 65 2e-10
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 65 2e-10
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 65 2e-10
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 65 2e-10
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 65 2e-10
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 65 2e-10
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 65 2e-10
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 65 2e-10
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 65 2e-10
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 65 3e-10
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 65 3e-10
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 65 3e-10
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 65 3e-10
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 65 3e-10
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 64 4e-10
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 64 4e-10
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 64 6e-10
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 63 1e-09
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 62 2e-09
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 62 3e-09
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 62 3e-09
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 62 3e-09
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 62 3e-09
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 62 3e-09
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 62 3e-09
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 62 3e-09
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 62 3e-09
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 61 4e-09
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 60 7e-09
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 60 7e-09
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 60 7e-09
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 60 7e-09
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 60 7e-09
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 60 1e-08
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 60 1e-08
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 60 1e-08
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 60 1e-08
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 60 1e-08
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 58 3e-08
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 58 3e-08
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 58 5e-08
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 58 5e-08
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 58 5e-08
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 57 7e-08
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 57 9e-08
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 56 2e-07
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 56 2e-07
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 56 2e-07
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 56 2e-07
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 56 2e-07
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 56 2e-07
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 56 2e-07
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 56 2e-07
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 56 2e-07
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 56 2e-07
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 56 2e-07
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 56 2e-07
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 56 2e-07
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 55 4e-07
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 55 4e-07
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 55 4e-07
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 55 4e-07
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 55 4e-07
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 55 4e-07
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 55 4e-07
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 55 4e-07
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 55 4e-07
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 55 4e-07
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 55 4e-07
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 55 4e-07
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 52 2e-06
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 52 2e-06
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 52 2e-06
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 52 2e-06
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 52 2e-06
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 52 2e-06
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 51 4e-06
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 51 4e-06
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 51 6e-06
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 51 6e-06
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 51 6e-06
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 50 8e-06
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 50 1e-05
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 50 1e-05
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 50 1e-05
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 50 1e-05
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 50 1e-05
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 50 1e-05
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 50 1e-05
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 50 1e-05
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 50 1e-05
AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase h... 50 1e-05
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 49 2e-05
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 48 3e-05
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 48 3e-05
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 48 3e-05
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 48 4e-05
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 48 4e-05
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 48 4e-05
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 48 4e-05
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 48 4e-05
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 48 4e-05
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 48 4e-05
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 48 4e-05
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 47 7e-05
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 47 7e-05
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 47 7e-05
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 47 9e-05
BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein. 46 2e-04
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 46 2e-04
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 46 2e-04
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 46 2e-04
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 45 3e-04
AY268353-1|AAP42287.1| 199|Homo sapiens short-chain dehydrogena... 45 4e-04
AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid ... 44 5e-04
M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid de... 43 0.001
M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase pro... 43 0.002
BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase (... 43 0.002
AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase (... 43 0.002
CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase... 42 0.004
BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase... 42 0.004
BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein. 42 0.004
AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein. 42 0.004
AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase... 42 0.004
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 42 0.004
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 41 0.005
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 41 0.005
BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase... 41 0.005
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 41 0.005
AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase... 41 0.005
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 41 0.006
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 40 0.008
M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein. 40 0.014
J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein. 40 0.014
EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1 pr... 40 0.014
CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein. 40 0.014
BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1 pr... 40 0.014
BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1 pr... 40 0.014
BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1 pr... 40 0.014
AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase (NAP... 40 0.014
AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1 pr... 40 0.014
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 40 0.014
AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1 pr... 40 0.014
AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase prot... 40 0.014
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 39 0.025
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 38 0.033
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 38 0.033
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 38 0.057
BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein. 37 0.100
BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 1... 37 0.100
AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein. 37 0.100
AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein. 37 0.100
AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein. 37 0.100
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 36 0.17
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 36 0.17
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 36 0.17
CR381696-1|CAI95409.1| 245|Homo sapiens dehydrogenase/reductase... 36 0.23
BX649443-1|CAI95430.1| 245|Homo sapiens dehydrogenase/reductase... 36 0.23
BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein. 36 0.23
BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein. 36 0.23
AY313896-1|AAP83168.1| 234|Homo sapiens short-chain dehydrogena... 36 0.23
AY268351-1|AAP42285.1| 205|Homo sapiens short-chain dehydrogena... 36 0.23
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 35 0.30
AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein. 35 0.30
AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase p... 35 0.30
AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein. 35 0.40
AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens ... 35 0.40
AL023881-3|CAO77956.1| 211|Homo sapiens 2,4-dienoyl CoA reducta... 34 0.53
AK128012-1|BAC87232.1| 211|Homo sapiens protein ( Homo sapiens ... 34 0.53
AF240697-1|AAF82747.1| 172|Homo sapiens retinol dehydrogenase h... 34 0.70
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 33 0.93
CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase... 33 1.2
BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase... 33 1.2
BC072434-1|AAH72434.1| 152|Homo sapiens HSD11B1L protein protein. 33 1.2
BC053546-1|AAH53546.1| 152|Homo sapiens hydroxysteroid (11-beta... 33 1.2
AY313895-1|AAP83167.1| 181|Homo sapiens short-chain dehydrogena... 33 1.2
AY268354-1|AAP42288.1| 152|Homo sapiens short-chain dehydrogena... 33 1.2
AL137300-1|CAB70685.1| 204|Homo sapiens hypothetical protein pr... 33 1.2
BC015582-1|AAH15582.1| 327|Homo sapiens dehydrogenase/reductase... 33 1.6
U13219-1|AAC50399.1| 354|Homo sapiens FREAC-1 protein. 32 2.8
DQ338571-1|ABC61321.1| 160|Homo sapiens NADP(H)-dependent retin... 32 2.8
BC089442-1|AAH89442.1| 354|Homo sapiens forkhead box F1 protein. 32 2.8
AY943857-1|AAX49568.1| 57|Homo sapiens NADP(H)-dependent retin... 32 2.8
AY616183-1|AAT70758.1| 91|Homo sapiens NADP(H)-dependent retin... 32 2.8
AF085343-1|AAC61576.1| 354|Homo sapiens forkhead transcription ... 32 2.8
M59911-1|AAA36120.1| 1051|Homo sapiens integrin alpha-3 chain pr... 31 3.7
D01038-1|BAA00845.1| 1019|Homo sapiens VLA-3 alpha subunit protein. 31 3.7
BC150190-1|AAI50191.1| 1051|Homo sapiens integrin, alpha 3 (anti... 31 3.7
BC112230-1|AAI12231.1| 716|Homo sapiens macrophage expressed ge... 31 6.5
BC104997-1|AAI04998.1| 716|Homo sapiens macrophage expressed ge... 31 6.5
AK074166-1|BAB84992.1| 717|Homo sapiens FLJ00239 protein protein. 31 6.5
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 106 bits (254), Expect = 1e-22
Identities = 72/248 (29%), Positives = 120/248 (48%), Gaps = 5/248 (2%)
Frame = -3
Query: 773 FTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKAD 594
+ KVV+VT F GA V I ++ ++ R Q + I D
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD----ESGGRALEQELPGAVFILCD 62
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
++ +++ KT+V +TI FG+LD ++NNAG + + + + NL +T
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 413 SLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANI 234
LA P+L +++GN+IN+SS+ G + + Y K ++ T+ +AL+ +P GVR N
Sbjct: 123 KLALPYLRKSQGNVINISSLVGA-IGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181
Query: 233 ISPGPVLTDIIEN-----SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
ISPG + T + E D + S A L ++G+P+E+ +FLAS+ A TG
Sbjct: 182 ISPGNIWTPLWEELAALMPDPRASIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTG 240
Query: 68 SNYVSDNG 45
+ G
Sbjct: 241 IELLVTGG 248
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 105 bits (251), Expect = 3e-22
Identities = 71/248 (28%), Positives = 120/248 (48%), Gaps = 5/248 (2%)
Frame = -3
Query: 773 FTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKAD 594
+ KVV+VT F GA V I ++ ++ R Q + I D
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD----ESGGRALEQELPGAVFILCD 62
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
++ +++ KT+V +TI FG+LD ++NNAG + + + + NL +T
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 413 SLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANI 234
LA P+L +++GN+IN+SS+ G + + Y K ++ T+ +AL+ +P GVR N
Sbjct: 123 KLALPYLRKSQGNVINISSLVGA-IGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181
Query: 233 ISPGPVLTDIIEN-----SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
ISPG + T + E D + + A L ++G+P+E+ +FLAS+ A TG
Sbjct: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTG 240
Query: 68 SNYVSDNG 45
+ G
Sbjct: 241 IELLVTGG 248
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 105 bits (251), Expect = 3e-22
Identities = 71/248 (28%), Positives = 120/248 (48%), Gaps = 5/248 (2%)
Frame = -3
Query: 773 FTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKAD 594
+ KVV+VT F GA V I ++ ++ R Q + I D
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD----ESGGRALEQELPGAVFILCD 62
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
++ +++ KT+V +TI FG+LD ++NNAG + + + + NL +T
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 413 SLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANI 234
LA P+L +++GN+IN+SS+ G + + Y K ++ T+ +AL+ +P GVR N
Sbjct: 123 KLALPYLRKSQGNVINISSLVGA-IGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181
Query: 233 ISPGPVLTDIIEN-----SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
ISPG + T + E D + + A L ++G+P+E+ +FLAS+ A TG
Sbjct: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTG 240
Query: 68 SNYVSDNG 45
+ G
Sbjct: 241 IELLVTGG 248
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 105 bits (251), Expect = 3e-22
Identities = 71/248 (28%), Positives = 120/248 (48%), Gaps = 5/248 (2%)
Frame = -3
Query: 773 FTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKAD 594
+ KVV+VT F GA V I ++ ++ R Q + I D
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKD----ESGGRALEQELPGAVFILCD 62
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
++ +++ KT+V +TI FG+LD ++NNAG + + + + NL +T
Sbjct: 63 VTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLT 122
Query: 413 SLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANI 234
LA P+L +++GN+IN+SS+ G + + Y K ++ T+ +AL+ +P GVR N
Sbjct: 123 KLALPYLRKSQGNVINISSLVGA-IGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNC 181
Query: 233 ISPGPVLTDIIEN-----SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
ISPG + T + E D + + A L ++G+P+E+ +FLAS+ A TG
Sbjct: 182 ISPGNIWTPLWEELAALMPDPRATIREGMLAQPLGRMGQPAEVGAAAVFLASE-ANFCTG 240
Query: 68 SNYVSDNG 45
+ G
Sbjct: 241 IELLVTGG 248
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 105 bits (251), Expect = 3e-22
Identities = 70/248 (28%), Positives = 115/248 (46%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
NKV LVT A A++GA V + R +D G +
Sbjct: 14 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVG 73
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + G +D+L++NA +N L E +D N++A L+T
Sbjct: 74 KAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTKA 133
Query: 407 AAPHLIETKG-NIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANII 231
P + + G +++ VSSI P PGF Y + K +L T+ +A+ELAPR +R N +
Sbjct: 134 VVPEMEKRGGGSVVIVSSIAA-FSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 192
Query: 230 SPGPVLTDIIENSDNQISW------DIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
+PG +I+ S +++ W + + +++LGEP + A ++ FL S+ A ITG
Sbjct: 193 APG-----LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITG 247
Query: 68 SNYVSDNG 45
V G
Sbjct: 248 ETVVVGGG 255
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 103 bits (248), Expect = 6e-22
Identities = 69/248 (27%), Positives = 115/248 (46%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
NKV LVT A A++GA V + R +D G +
Sbjct: 32 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVG 91
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + G +D+L++NA +N + E +D N++A L+T
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 151
Query: 407 AAPHLIETKG-NIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANII 231
P + + G +++ VSSI P PGF Y + K +L T+ +A+ELAPR +R N +
Sbjct: 152 VVPEMEKRGGGSVVIVSSIAA-FSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 230 SPGPVLTDIIENSDNQISW------DIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
+PG +I+ S +++ W + + +++LGEP + A ++ FL S+ A ITG
Sbjct: 211 APG-----LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITG 265
Query: 68 SNYVSDNG 45
V G
Sbjct: 266 ETVVVGGG 273
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 103 bits (248), Expect = 6e-22
Identities = 69/248 (27%), Positives = 115/248 (46%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
NKV LVT A A++GA V + R +D G +
Sbjct: 32 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVG 91
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + G +D+L++NA +N + E +D N++A L+T
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 151
Query: 407 AAPHLIETKG-NIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANII 231
P + + G +++ VSSI P PGF Y + K +L T+ +A+ELAPR +R N +
Sbjct: 152 VVPEMEKRGGGSVVIVSSIAA-FSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 230 SPGPVLTDIIENSDNQISW------DIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
+PG +I+ S +++ W + + +++LGEP + A ++ FL S+ A ITG
Sbjct: 211 APG-----LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITG 265
Query: 68 SNYVSDNG 45
V G
Sbjct: 266 ETVVVGGG 273
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 103 bits (248), Expect = 6e-22
Identities = 69/248 (27%), Positives = 115/248 (46%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
NKV LVT A A++GA V + R +D G +
Sbjct: 32 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVG 91
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + G +D+L++NA +N + E +D N++A L+T
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 151
Query: 407 AAPHLIETKG-NIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANII 231
P + + G +++ VSSI P PGF Y + K +L T+ +A+ELAPR +R N +
Sbjct: 152 VVPEMEKRGGGSVVIVSSIAA-FSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 230 SPGPVLTDIIENSDNQISW------DIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
+PG +I+ S +++ W + + +++LGEP + A ++ FL S+ A ITG
Sbjct: 211 APG-----LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITG 265
Query: 68 SNYVSDNG 45
V G
Sbjct: 266 ETVVVGGG 273
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 103 bits (248), Expect = 6e-22
Identities = 69/248 (27%), Positives = 115/248 (46%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
NKV LVT A A++GA V + R +D G +
Sbjct: 14 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVG 73
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + G +D+L++NA +N + E +D N++A L+T
Sbjct: 74 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 133
Query: 407 AAPHLIETKG-NIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANII 231
P + + G +++ VSSI P PGF Y + K +L T+ +A+ELAPR +R N +
Sbjct: 134 VVPEMEKRGGGSVVIVSSIAA-FSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 192
Query: 230 SPGPVLTDIIENSDNQISW------DIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
+PG +I+ S +++ W + + +++LGEP + A ++ FL S+ A ITG
Sbjct: 193 APG-----LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITG 247
Query: 68 SNYVSDNG 45
V G
Sbjct: 248 ETVVVGGG 255
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 103 bits (246), Expect = 1e-21
Identities = 65/236 (27%), Positives = 112/236 (47%), Gaps = 1/236 (0%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
N+V +VT A A++GA V I R +D + G I +
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVG 95
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + ++ G +D L+ +AG+N G + +D + + N+++ L+ S
Sbjct: 96 KAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQ 155
Query: 407 AAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIIS 228
P++ +G +I VSSI P+ Y + K +L TR +ALELAP+ +R N +
Sbjct: 156 LLPYMENRRGAVILVSSI-AAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVV 214
Query: 227 PGPVLTDIIE-NSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSN 63
PG + TD + N+ W F+ L+++GE + A ++ FL S A + G N
Sbjct: 215 PGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGEN 270
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 103 bits (246), Expect = 1e-21
Identities = 65/236 (27%), Positives = 112/236 (47%), Gaps = 1/236 (0%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
N+V +VT A A++GA V I R +D + G I +
Sbjct: 27 NRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVG 86
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + ++ G +D L+ +AG+N G + +D + + N+++ L+ S
Sbjct: 87 KAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQ 146
Query: 407 AAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIIS 228
P++ +G +I VSSI P+ Y + K +L TR +ALELAP+ +R N +
Sbjct: 147 LLPYMENRRGAVILVSSI-AAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVV 205
Query: 227 PGPVLTDIIE-NSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSN 63
PG + TD + N+ W F+ L+++GE + A ++ FL S A + G N
Sbjct: 206 PGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGEN 261
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 103 bits (246), Expect = 1e-21
Identities = 65/236 (27%), Positives = 112/236 (47%), Gaps = 1/236 (0%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
N+V +VT A A++GA V I R +D + G I +
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVG 95
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + ++ G +D L+ +AG+N G + +D + + N+++ L+ S
Sbjct: 96 KAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQ 155
Query: 407 AAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIIS 228
P++ +G +I VSSI P+ Y + K +L TR +ALELAP+ +R N +
Sbjct: 156 LLPYMENRRGAVILVSSI-AAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVV 214
Query: 227 PGPVLTDIIE-NSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSN 63
PG + TD + N+ W F+ L+++GE + A ++ FL S A + G N
Sbjct: 215 PGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGEN 270
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 103 bits (246), Expect = 1e-21
Identities = 69/248 (27%), Positives = 115/248 (46%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
NKV LVT A A++GA V + R +D G +
Sbjct: 32 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCMVG 91
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + G +D+L++NA +N + E +D N++A L+T
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 151
Query: 407 AAPHLIETKG-NIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANII 231
P + + G +++ VSSI P PGF Y + K +L T+ +A+ELAPR +R N +
Sbjct: 152 VVPEMEKRGGGSVVIVSSIAA-FSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 230 SPGPVLTDIIENSDNQISW------DIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
+PG +I+ S +++ W + + +++LGEP + A ++ FL S+ A ITG
Sbjct: 211 APG-----LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITG 265
Query: 68 SNYVSDNG 45
V G
Sbjct: 266 ETVVVGGG 273
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 102 bits (244), Expect = 2e-21
Identities = 68/248 (27%), Positives = 114/248 (45%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
NKV L T A A++GA V + R +D G +
Sbjct: 32 NKVALATASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVG 91
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + G +D+L++NA +N + E +D N++A L+T
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALMTKA 151
Query: 407 AAPHLIETKG-NIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANII 231
P + + G +++ VSSI P PGF Y + K +L T+ +A+ELAPR +R N +
Sbjct: 152 VVPEMEKRGGGSVVIVSSIAA-FSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCL 210
Query: 230 SPGPVLTDIIENSDNQISW------DIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
+PG +I+ S +++ W + + +++LGEP + A ++ FL S+ A ITG
Sbjct: 211 APG-----LIKTSFSRMLWMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITG 265
Query: 68 SNYVSDNG 45
V G
Sbjct: 266 ETVVVGGG 273
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 101 bits (243), Expect = 2e-21
Identities = 63/199 (31%), Positives = 102/199 (51%), Gaps = 6/199 (3%)
Frame = -3
Query: 770 TNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVG----KKPLII 603
T+ VV VT A +K G + + R V +L+ V R C + G K L++
Sbjct: 49 TDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVL 108
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVI 423
D+++ + + + FG++D+L+NN GM++ SL L+ Y + N +
Sbjct: 109 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQR-SLCMDTSLDVYRKLIELNYLGTV 167
Query: 422 LITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RG 249
+T PH+IE K G I+ V+SI G ++ +P + YC K +L F G+ ELA G
Sbjct: 168 SLTKCVLPHMIERKQGKIVTVNSILG-IISVPLSIGYCASKHALRGFFNGLRTELATYPG 226
Query: 248 VRANIISPGPVLTDIIENS 192
+ + I PGPV ++I+ENS
Sbjct: 227 IIVSNICPGPVQSNIVENS 245
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 101 bits (243), Expect = 2e-21
Identities = 63/199 (31%), Positives = 102/199 (51%), Gaps = 6/199 (3%)
Frame = -3
Query: 770 TNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVG----KKPLII 603
T+ VV VT A +K G + + R V +L+ V R C + G K L++
Sbjct: 49 TDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVL 108
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVI 423
D+++ + + + FG++D+L+NN GM++ SL L+ Y + N +
Sbjct: 109 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQR-SLCMDTSLDVYRKLIELNYLGTV 167
Query: 422 LITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RG 249
+T PH+IE K G I+ V+SI G ++ +P + YC K +L F G+ ELA G
Sbjct: 168 SLTKCVLPHMIERKQGKIVTVNSILG-IISVPLSIGYCASKHALRGFFNGLRTELATYPG 226
Query: 248 VRANIISPGPVLTDIIENS 192
+ + I PGPV ++I+ENS
Sbjct: 227 IIVSNICPGPVQSNIVENS 245
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 101 bits (243), Expect = 2e-21
Identities = 63/199 (31%), Positives = 102/199 (51%), Gaps = 6/199 (3%)
Frame = -3
Query: 770 TNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVG----KKPLII 603
T+ VV VT A +K G + + R V +L+ V R C + G K L++
Sbjct: 49 TDMVVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVL 108
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVI 423
D+++ + + + FG++D+L+NN GM++ SL L+ Y + N +
Sbjct: 109 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQR-SLCMDTSLDVYRKLIELNYLGTV 167
Query: 422 LITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RG 249
+T PH+IE K G I+ V+SI G ++ +P + YC K +L F G+ ELA G
Sbjct: 168 SLTKCVLPHMIERKQGKIVTVNSILG-IISVPLSIGYCASKHALRGFFNGLRTELATYPG 226
Query: 248 VRANIISPGPVLTDIIENS 192
+ + I PGPV ++I+ENS
Sbjct: 227 IIVSNICPGPVQSNIVENS 245
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 100 bits (240), Expect = 5e-21
Identities = 63/236 (26%), Positives = 111/236 (47%), Gaps = 1/236 (0%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
N+V +VT A A++GA V I R +D + G I +
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVG 95
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + ++ G +D L+ +AG+N G + +D + + N+++ + S
Sbjct: 96 KAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPAPLLSQ 155
Query: 407 AAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIIS 228
P++ +G +I VSS+ P+ Y + K +L TR +ALELAP+ +R N +
Sbjct: 156 LLPYMENRRGAVILVSSV-AAYNPVVALGVYSVSKTALLGLTRTLALELAPKDIRVNCVV 214
Query: 227 PGPVLTDIIE-NSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSN 63
PG + TD + N+ W F+ L+++GE + A ++ FL S A + G N
Sbjct: 215 PGIIKTDFSKVFHGNESLWKNFKEHHQLQRIGESEDCAGIVSFLCSPDASYVNGEN 270
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 99 bits (238), Expect = 9e-21
Identities = 62/196 (31%), Positives = 100/196 (51%), Gaps = 6/196 (3%)
Frame = -3
Query: 761 VVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVG----KKPLIIKAD 594
VV VT A +K G + + R V +L+ V R C + G K L++ D
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 61
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
+++ + + + FG++D+L+NN GM++ SL L+ Y + N + +T
Sbjct: 62 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQR-SLCMDTSLDVYRKLIELNYLGTVSLT 120
Query: 413 SLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RGVRA 240
PH+IE K G I+ V+SI G ++ +P + YC K +L F G+ ELA G+
Sbjct: 121 KCVLPHMIERKQGKIVTVNSILG-IISVPLSIGYCASKHALRGFFNGLRTELATYPGIIV 179
Query: 239 NIISPGPVLTDIIENS 192
+ I PGPV ++I+ENS
Sbjct: 180 SNICPGPVQSNIVENS 195
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 99 bits (238), Expect = 9e-21
Identities = 62/196 (31%), Positives = 100/196 (51%), Gaps = 6/196 (3%)
Frame = -3
Query: 761 VVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVG----KKPLIIKAD 594
VV VT A +K G + + R V +L+ V R C + G K L++ D
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 61
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
+++ + + + FG++D+L+NN GM++ SL L+ Y + N + +T
Sbjct: 62 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQR-SLCMDTSLDVYRKLIELNYLGTVSLT 120
Query: 413 SLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RGVRA 240
PH+IE K G I+ V+SI G ++ +P + YC K +L F G+ ELA G+
Sbjct: 121 KCVLPHMIERKQGKIVTVNSILG-IISVPLSIGYCASKHALRGFFNGLRTELATYPGIIV 179
Query: 239 NIISPGPVLTDIIENS 192
+ I PGPV ++I+ENS
Sbjct: 180 SNICPGPVQSNIVENS 195
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 87.0 bits (206), Expect = 7e-17
Identities = 70/250 (28%), Positives = 115/250 (46%), Gaps = 10/250 (4%)
Frame = -3
Query: 761 VVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP-------LII 603
+ LVT +V A EGA VA + R G K
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 602 KADISNDEEAKTIVQQTIDAFGKL-DVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+AD+S A+ +++Q F + V+++ AG+ + LL + + +D V A NL+
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE-DDWDKVIAVNLKGT 131
Query: 425 ILITSLAAPHLIET--KGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR 252
L+T AA L+ +G+IIN+SSI G V G Y KA + T+ A EL
Sbjct: 132 FLVTQAAAQALVSNGCRGSIINISSIVGK-VGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 251 GVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSIT 72
G+R N + PG + T + + ++ D + LG+P ++A+++ FLAS+ + IT
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVV-DKITEMIPMGHLGDPEDVADVVAFLASEDSGYIT 249
Query: 71 GSNYVSDNGM 42
G++ G+
Sbjct: 250 GTSVEVTGGL 259
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 87.0 bits (206), Expect = 7e-17
Identities = 70/250 (28%), Positives = 115/250 (46%), Gaps = 10/250 (4%)
Frame = -3
Query: 761 VVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP-------LII 603
+ LVT +V A EGA VA + R G K
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 602 KADISNDEEAKTIVQQTIDAFGKL-DVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+AD+S A+ +++Q F + V+++ AG+ + LL + + +D V A NL+
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE-DDWDKVIAVNLKGT 131
Query: 425 ILITSLAAPHLIET--KGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR 252
L+T AA L+ +G+IIN+SSI G V G Y KA + T+ A EL
Sbjct: 132 FLVTQAAAQALVSNGCRGSIINISSIVGK-VGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 251 GVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSIT 72
G+R N + PG + T + + ++ D + LG+P ++A+++ FLAS+ + IT
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVV-DKITEMIPMGHLGDPEDVADVVAFLASEDSGYIT 249
Query: 71 GSNYVSDNGM 42
G++ G+
Sbjct: 250 GTSVEVTGGL 259
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 87.0 bits (206), Expect = 7e-17
Identities = 70/250 (28%), Positives = 115/250 (46%), Gaps = 10/250 (4%)
Frame = -3
Query: 761 VVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP-------LII 603
+ LVT +V A EGA VA + R G K
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 602 KADISNDEEAKTIVQQTIDAFGKL-DVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+AD+S A+ +++Q F + V+++ AG+ + LL + + +D V A NL+
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE-DDWDKVIAVNLKGT 131
Query: 425 ILITSLAAPHLIET--KGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR 252
L+T AA L+ +G+IIN+SSI G V G Y KA + T+ A EL
Sbjct: 132 FLVTQAAAQALVSNGCRGSIINISSIVGK-VGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 251 GVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSIT 72
G+R N + PG + T + + ++ D + LG+P ++A+++ FLAS+ + IT
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVV-DKITEMIPMGHLGDPEDVADVVAFLASEDSGYIT 249
Query: 71 GSNYVSDNGM 42
G++ G+
Sbjct: 250 GTSVEVTGGL 259
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 87.0 bits (206), Expect = 7e-17
Identities = 70/250 (28%), Positives = 115/250 (46%), Gaps = 10/250 (4%)
Frame = -3
Query: 761 VVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP-------LII 603
+ LVT +V A EGA VA + R G K
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 602 KADISNDEEAKTIVQQTIDAFGKL-DVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+AD+S A+ +++Q F + V+++ AG+ + LL + + +D V A NL+
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE-DDWDKVIAVNLKGT 131
Query: 425 ILITSLAAPHLIET--KGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR 252
L+T AA L+ +G+IIN+SSI G V G Y KA + T+ A EL
Sbjct: 132 FLVTQAAAQALVSNGCRGSIINISSIVGK-VGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 251 GVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSIT 72
G+R N + PG + T + + ++ D + LG+P ++A+++ FLAS+ + IT
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVV-DKITEMIPMGHLGDPEDVADVVAFLASEDSGYIT 249
Query: 71 GSNYVSDNGM 42
G++ G+
Sbjct: 250 GTSVEVTGGL 259
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 87.0 bits (206), Expect = 7e-17
Identities = 70/250 (28%), Positives = 115/250 (46%), Gaps = 10/250 (4%)
Frame = -3
Query: 761 VVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP-------LII 603
+ LVT +V A EGA VA + R G K
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 602 KADISNDEEAKTIVQQTIDAFGKL-DVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+AD+S A+ +++Q F + V+++ AG+ + LL + + +D V A NL+
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE-DDWDKVIAVNLKGT 131
Query: 425 ILITSLAAPHLIET--KGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR 252
L+T AA L+ +G+IIN+SSI G V G Y KA + T+ A EL
Sbjct: 132 FLVTQAAAQALVSNGCRGSIINISSIVGK-VGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 251 GVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSIT 72
G+R N + PG + T + + ++ D + LG+P ++A+++ FLAS+ + IT
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVV-DKITEMIPMGHLGDPEDVADVVAFLASEDSGYIT 249
Query: 71 GSNYVSDNGM 42
G++ G+
Sbjct: 250 GTSVEVTGGL 259
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 87.0 bits (206), Expect = 7e-17
Identities = 70/250 (28%), Positives = 115/250 (46%), Gaps = 10/250 (4%)
Frame = -3
Query: 761 VVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP-------LII 603
+ LVT +V A EGA VA + R G K
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 602 KADISNDEEAKTIVQQTIDAFGKL-DVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+AD+S A+ +++Q F + V+++ AG+ + LL + + +D V A NL+
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE-DDWDKVIAVNLKGT 131
Query: 425 ILITSLAAPHLIET--KGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR 252
L+T AA L+ +G+IIN+SSI G V G Y KA + T+ A EL
Sbjct: 132 FLVTQAAAQALVSNGCRGSIINISSIVGK-VGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 251 GVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSIT 72
G+R N + PG + T + + ++ D + LG+P ++A+++ FLAS+ + IT
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVV-DKITEMIPMGHLGDPEDVADVVAFLASEDSGYIT 249
Query: 71 GSNYVSDNGM 42
G++ G+
Sbjct: 250 GTSVEVTGGL 259
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 87.0 bits (206), Expect = 7e-17
Identities = 70/250 (28%), Positives = 115/250 (46%), Gaps = 10/250 (4%)
Frame = -3
Query: 761 VVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP-------LII 603
+ LVT +V A EGA VA + R G K
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 602 KADISNDEEAKTIVQQTIDAFGKL-DVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+AD+S A+ +++Q F + V+++ AG+ + LL + + +D V A NL+
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSE-DDWDKVIAVNLKGT 131
Query: 425 ILITSLAAPHLIET--KGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR 252
L+T AA L+ +G+IIN+SSI G V G Y KA + T+ A EL
Sbjct: 132 FLVTQAAAQALVSNGCRGSIINISSIVGK-VGNVGQTNYAASKAGVIGLTQTAARELGRH 190
Query: 251 GVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSIT 72
G+R N + PG + T + + ++ D + LG+P ++A+++ FLAS+ + IT
Sbjct: 191 GIRCNSVLPGFIATPMTQKVPQKVV-DKITEMIPMGHLGDPEDVADVVAFLASEDSGYIT 249
Query: 71 GSNYVSDNGM 42
G++ G+
Sbjct: 250 GTSVEVTGGL 259
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 87.0 bits (206), Expect = 7e-17
Identities = 74/225 (32%), Positives = 110/225 (48%), Gaps = 8/225 (3%)
Frame = -3
Query: 695 GADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLIN 516
GA V V R LD++ REC G +P+ + D+ D EA ++ + + G +D+L+N
Sbjct: 31 GARVVAVSRTQADLDSLVRECP--GIEPVCV--DLG-DWEA---TERALGSVGPVDLLVN 82
Query: 515 NAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIE--TKGNIINVSSIGGTM 342
NA + L E++D NLRAVI ++ +AA LI G I+NVSS
Sbjct: 83 NAAVALLQPFLEVTK-EAFDRSFEVNLRAVIQVSQIAARGLIARGVPGAIVNVSSQCSQR 141
Query: 341 VPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISW-DIF 165
+ YC K +L+ T+ +ALEL P +R N ++P V+T S Q +W D
Sbjct: 142 A-VTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMT-----SMGQATWSDPH 195
Query: 164 RAATALK-----KLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+A T L K E + +LFL SD++ TGS + G
Sbjct: 196 KAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 85.4 bits (202), Expect = 2e-16
Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 8/225 (3%)
Frame = -3
Query: 695 GADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLIN 516
GA V V R LD++ REC G +P+ + D+ D EA ++ + + G +D+L+N
Sbjct: 31 GARVVAVSRTQADLDSLVRECP--GIEPVCV--DLG-DWEA---TERALGSVGPVDLLVN 82
Query: 515 NAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIE--TKGNIINVSSIGGTM 342
NA + L E++D NLRAVI ++ + A LI G I+NVSS
Sbjct: 83 NAAVALLQPFLEVTK-EAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQR 141
Query: 341 VPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISW-DIF 165
+ YC K +L+ T+ +ALEL P +R N ++P V+T S Q +W D
Sbjct: 142 A-VTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMT-----SMGQATWSDPH 195
Query: 164 RAATALK-----KLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+A T L K E + +LFL SD++ TGS + G
Sbjct: 196 KAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 85.4 bits (202), Expect = 2e-16
Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 8/225 (3%)
Frame = -3
Query: 695 GADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLIN 516
GA V V R LD++ REC G +P+ + D+ D EA ++ + + G +D+L+N
Sbjct: 30 GARVVAVSRTQADLDSLVRECP--GIEPVCV--DLG-DWEA---TERALGSVGPVDLLVN 81
Query: 515 NAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIE--TKGNIINVSSIGGTM 342
NA + L E++D NLRAVI ++ + A LI G I+NVSS
Sbjct: 82 NAAVALLQPFLEVTK-EAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQR 140
Query: 341 VPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISW-DIF 165
+ YC K +L+ T+ +ALEL P +R N ++P V+T S Q +W D
Sbjct: 141 A-VTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMT-----SMGQATWSDPH 194
Query: 164 RAATALK-----KLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+A T L K E + +LFL SD++ TGS + G
Sbjct: 195 KAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 239
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 85.4 bits (202), Expect = 2e-16
Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 8/225 (3%)
Frame = -3
Query: 695 GADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLIN 516
GA V V R LD++ REC G +P+ + D+ D EA ++ + + G +D+L+N
Sbjct: 31 GARVVAVSRTQADLDSLVRECP--GIEPVCV--DLG-DWEA---TERALGSVGPVDLLVN 82
Query: 515 NAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIE--TKGNIINVSSIGGTM 342
NA + L E++D NLRAVI ++ + A LI G I+NVSS
Sbjct: 83 NAAVALLQPFLEVTK-EAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQR 141
Query: 341 VPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISW-DIF 165
+ YC K +L+ T+ +ALEL P +R N ++P V+T S Q +W D
Sbjct: 142 A-VTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMT-----SMGQATWSDPH 195
Query: 164 RAATALK-----KLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+A T L K E + +LFL SD++ TGS + G
Sbjct: 196 KAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 85.4 bits (202), Expect = 2e-16
Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 8/225 (3%)
Frame = -3
Query: 695 GADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLIN 516
GA V V R LD++ REC G +P+ + D+ D EA ++ + + G +D+L+N
Sbjct: 31 GARVVAVSRTQADLDSLVRECP--GIEPVCV--DLG-DWEA---TERALGSVGPVDLLVN 82
Query: 515 NAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIE--TKGNIINVSSIGGTM 342
NA + L E++D NLRAVI ++ + A LI G I+NVSS
Sbjct: 83 NAAVALLQPFLEVTK-EAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQR 141
Query: 341 VPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISW-DIF 165
+ YC K +L+ T+ +ALEL P +R N ++P V+T S Q +W D
Sbjct: 142 A-VTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMT-----SMGQATWSDPH 195
Query: 164 RAATALK-----KLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+A T L K E + +LFL SD++ TGS + G
Sbjct: 196 KAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 85.4 bits (202), Expect = 2e-16
Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 8/225 (3%)
Frame = -3
Query: 695 GADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLIN 516
GA V V R LD++ REC G +P+ + D+ D EA ++ + + G +D+L+N
Sbjct: 31 GARVVAVSRTQADLDSLVRECP--GIEPVCV--DLG-DWEA---TERALGSVGPVDLLVN 82
Query: 515 NAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIE--TKGNIINVSSIGGTM 342
NA + L E++D NLRAVI ++ + A LI G I+NVSS
Sbjct: 83 NAAVALLQPFLEVTK-EAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQR 141
Query: 341 VPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISW-DIF 165
+ YC K +L+ T+ +ALEL P +R N ++P V+T S Q +W D
Sbjct: 142 A-VTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMT-----SMGQATWSDPH 195
Query: 164 RAATALK-----KLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+A T L K E + +LFL SD++ TGS + G
Sbjct: 196 KAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 85.4 bits (202), Expect = 2e-16
Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 8/225 (3%)
Frame = -3
Query: 695 GADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLIN 516
GA V V R LD++ REC G +P+ + D+ D EA ++ + + G +D+L+N
Sbjct: 31 GARVVAVSRTQADLDSLVRECP--GIEPVCV--DLG-DWEA---TERALGSVGPVDLLVN 82
Query: 515 NAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIE--TKGNIINVSSIGGTM 342
NA + L E++D NLRAVI ++ + A LI G I+NVSS
Sbjct: 83 NAAVALLQPFLEVTK-EAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQR 141
Query: 341 VPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISW-DIF 165
+ YC K +L+ T+ +ALEL P +R N ++P V+T S Q +W D
Sbjct: 142 A-VTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMT-----SMGQATWSDPH 195
Query: 164 RAATALK-----KLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+A T L K E + +LFL SD++ TGS + G
Sbjct: 196 KAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 85.4 bits (202), Expect = 2e-16
Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 8/225 (3%)
Frame = -3
Query: 695 GADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLIN 516
GA V V R LD++ REC G +P+ + D+ D EA ++ + + G +D+L+N
Sbjct: 31 GARVVAVSRTQADLDSLVRECP--GIEPVCV--DLG-DWEA---TERALGSVGPVDLLVN 82
Query: 515 NAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIE--TKGNIINVSSIGGTM 342
NA + L E++D NLRAVI ++ + A LI G I+NVSS
Sbjct: 83 NAAVALLQPFLEVTK-EAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQR 141
Query: 341 VPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISW-DIF 165
+ YC K +L+ T+ +ALEL P +R N ++P V+T S Q +W D
Sbjct: 142 A-VTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMT-----SMGQATWSDPH 195
Query: 164 RAATALK-----KLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+A T L K E + +LFL SD++ TGS + G
Sbjct: 196 KAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 85.4 bits (202), Expect = 2e-16
Identities = 73/225 (32%), Positives = 109/225 (48%), Gaps = 8/225 (3%)
Frame = -3
Query: 695 GADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLIN 516
GA V V R LD++ REC G +P+ + D+ D EA ++ + + G +D+L+N
Sbjct: 31 GARVVAVSRTQADLDSLVRECP--GIEPVCV--DLG-DWEA---TERALGSVGPVDLLVN 82
Query: 515 NAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIE--TKGNIINVSSIGGTM 342
NA + L E++D NLRAVI ++ + A LI G I+NVSS
Sbjct: 83 NAAVALLQPFLEVTK-EAFDRSFEVNLRAVIQVSQIVARGLIARGVPGAIVNVSSQCSQR 141
Query: 341 VPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISW-DIF 165
+ YC K +L+ T+ +ALEL P +R N ++P V+T S Q +W D
Sbjct: 142 A-VTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVMT-----SMGQATWSDPH 195
Query: 164 RAATALK-----KLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+A T L K E + +LFL SD++ TGS + G
Sbjct: 196 KAKTMLNRIPLGKFAEVEHVVNAILFLLSDRSGMTTGSTLPVEGG 240
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 84.2 bits (199), Expect = 5e-16
Identities = 69/250 (27%), Positives = 114/250 (45%), Gaps = 10/250 (4%)
Frame = -3
Query: 761 VVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP-------LII 603
+ LVT +V A EGA VA + R G K
Sbjct: 11 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 70
Query: 602 KADISNDEEAKTIVQQTIDAFGKL-DVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+AD+S A+ +++Q F + V+++ AG+ + LL + + +D V A NL+
Sbjct: 71 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSR-DDWDKVIAVNLKGT 129
Query: 425 ILITSLAAPHLIET--KGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR 252
L+T AA L+ +G+IIN+SSI G V G Y KA + T+ A EL
Sbjct: 130 FLVTQAAAQALVSNGCRGSIINISSIVGK-VGNVGQTNYAASKAGVIGLTQTAARELGRH 188
Query: 251 GVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSIT 72
G+ N + PG + T + + ++ D + LG+P ++A+++ FLAS+ + IT
Sbjct: 189 GIPCNSVLPGFIATPMTKKVPKKVV-DKITEMIPMGHLGDPEDVADVVAFLASEDSGYIT 247
Query: 71 GSNYVSDNGM 42
G++ G+
Sbjct: 248 GTSVEVTGGL 257
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 84.2 bits (199), Expect = 5e-16
Identities = 52/187 (27%), Positives = 89/187 (47%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
N+V +VT A A++GA V I R +D + G I +
Sbjct: 36 NRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVG 95
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSL 408
E+ + +V + ++ G +D L+ +AG+N G + +D + + N+++ L+ S
Sbjct: 96 KAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSPALLLSQ 155
Query: 407 AAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIIS 228
P++ +G +I VSSI P+ Y + K +L TR +ALELAP+ +R N +
Sbjct: 156 LLPYMENRRGAVILVSSI-AAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIRVNCVV 214
Query: 227 PGPVLTD 207
PG + TD
Sbjct: 215 PGIIKTD 221
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 83.4 bits (197), Expect = 9e-16
Identities = 61/222 (27%), Positives = 110/222 (49%), Gaps = 1/222 (0%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDV 525
A++G +A++ RN L+ +G L D++ + + + ++ G+++
Sbjct: 23 ARKGYRLAVIARN---LEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEELEKHLGRVNF 79
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKG-NIINVSSIGG 348
L+N AG+N+ G LL E + TNL +L A +I+ +G +I+NV SI G
Sbjct: 80 LVNAAGINRDG-LLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVG 138
Query: 347 TMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDI 168
+ G Y K L F+R +A E+A + +R N+++PG V TD+ ++ + +
Sbjct: 139 -LKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKD----LKEEH 193
Query: 167 FRAATALKKLGEPSEIAELMLFLASDKARSITGSNYVSDNGM 42
+ L + GE E+A ++FL ++ ITG V D G+
Sbjct: 194 LKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 83.4 bits (197), Expect = 9e-16
Identities = 61/222 (27%), Positives = 110/222 (49%), Gaps = 1/222 (0%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDV 525
A++G +A++ RN L+ +G L D++ + + + ++ G+++
Sbjct: 23 ARKGYRLAVIARN---LEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNF 79
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKG-NIINVSSIGG 348
L+N AG+N+ G LL E + TNL +L A +I+ +G +I+NV SI G
Sbjct: 80 LVNAAGINRDG-LLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVG 138
Query: 347 TMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDI 168
+ G Y K L F+R +A E+A + +R N+++PG V TD+ ++ + +
Sbjct: 139 -LKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVHTDMTKD----LKEEH 193
Query: 167 FRAATALKKLGEPSEIAELMLFLASDKARSITGSNYVSDNGM 42
+ L + GE E+A ++FL ++ ITG V D G+
Sbjct: 194 LKKNIPLGRFGETIEVAHAVVFLL--ESPYITGHVLVVDGGL 233
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 83.0 bits (196), Expect = 1e-15
Identities = 68/250 (27%), Positives = 118/250 (47%), Gaps = 10/250 (4%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP------LII 603
+V +VT + G++V I R + +L + A E Q P + I
Sbjct: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADEL-QANLPPTKQARVIPI 77
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVI 423
+ +I N+EE +V+ T+D FGK++ L+NN G + S + + AV TNL
Sbjct: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-GQFLSPAEHISSKGWHAVLETNLTGTF 136
Query: 422 -LITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGV 246
+ ++ + + E G+I+N+ I T P + +A + + T+ +ALE A G+
Sbjct: 137 YMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194
Query: 245 RANIISPGPVLTD-IIEN--SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSI 75
R N ++PG + + +EN S Q ++ K++G P E++ ++ FL S A I
Sbjct: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254
Query: 74 TGSNYVSDNG 45
TG + D G
Sbjct: 255 TGQSVDVDGG 264
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 83.0 bits (196), Expect = 1e-15
Identities = 68/250 (27%), Positives = 118/250 (47%), Gaps = 10/250 (4%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP------LII 603
+V +VT + G++V I R + +L + A E Q P + I
Sbjct: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADEL-QANLPPTKQARVIPI 77
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVI 423
+ +I N+EE +V+ T+D FGK++ L+NN G + S + + AV TNL
Sbjct: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-GQFLSPAEHISSKGWHAVLETNLTGTF 136
Query: 422 -LITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGV 246
+ ++ + + E G+I+N+ I T P + +A + + T+ +ALE A G+
Sbjct: 137 YMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194
Query: 245 RANIISPGPVLTD-IIEN--SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSI 75
R N ++PG + + +EN S Q ++ K++G P E++ ++ FL S A I
Sbjct: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254
Query: 74 TGSNYVSDNG 45
TG + D G
Sbjct: 255 TGQSVDVDGG 264
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 83.0 bits (196), Expect = 1e-15
Identities = 68/250 (27%), Positives = 118/250 (47%), Gaps = 10/250 (4%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP------LII 603
+V +VT + G++V I R + +L + A E Q P + I
Sbjct: 38 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADEL-QANLPPTKQARVIPI 96
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVI 423
+ +I N+EE +V+ T+D FGK++ L+NN G + S + + AV TNL
Sbjct: 97 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-GQFLSPAEHISSKGWHAVLETNLTGTF 155
Query: 422 -LITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGV 246
+ ++ + + E G+I+N+ I T P + +A + + T+ +ALE A G+
Sbjct: 156 YMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 213
Query: 245 RANIISPGPVLTD-IIEN--SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSI 75
R N ++PG + + +EN S Q ++ K++G P E++ ++ FL S A I
Sbjct: 214 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 273
Query: 74 TGSNYVSDNG 45
TG + D G
Sbjct: 274 TGQSVDVDGG 283
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 83.0 bits (196), Expect = 1e-15
Identities = 68/250 (27%), Positives = 118/250 (47%), Gaps = 10/250 (4%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP------LII 603
+V +VT + G++V I R + +L + A E Q P + I
Sbjct: 19 QVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADEL-QANLPPTKQARVIPI 77
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVI 423
+ +I N+EE +V+ T+D FGK++ L+NN G + S + + AV TNL
Sbjct: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-GQFLSPAEHISSKGWHAVLETNLTGTF 136
Query: 422 -LITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGV 246
+ ++ + + E G+I+N+ I T P + +A + + T+ +ALE A G+
Sbjct: 137 YMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194
Query: 245 RANIISPGPVLTD-IIEN--SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSI 75
R N ++PG + + +EN S Q ++ K++G P E++ ++ FL S A I
Sbjct: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254
Query: 74 TGSNYVSDNG 45
TG + D G
Sbjct: 255 TGQSVDVDGG 264
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 81.8 bits (193), Expect = 3e-15
Identities = 68/250 (27%), Positives = 118/250 (47%), Gaps = 10/250 (4%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP------LII 603
+V VT + G++V I R + +L + A E Q P + I
Sbjct: 19 QVAFVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADEL-QANLPPTKQARVIPI 77
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLR-AV 426
+ +I N+EE +V+ T+D FGK++ L+NN G + S + + AV TNL +
Sbjct: 78 QCNIRNEEEVNNLVKSTLDTFGKINFLVNNGG-GQFLSPAEHISSKGWHAVLRTNLTGSF 136
Query: 425 ILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGV 246
+ ++ + + E G+I+N+ I T P + +A + + T+ +ALE A G+
Sbjct: 137 YMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGI 194
Query: 245 RANIISPGPVLTD-IIEN--SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSI 75
R N ++PG + + +EN S Q ++ K++G P E++ ++ FL S A I
Sbjct: 195 RINCVAPGVIYSQTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAASFI 254
Query: 74 TGSNYVSDNG 45
TG + D G
Sbjct: 255 TGQSVDVDGG 264
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 80.6 bits (190), Expect = 6e-15
Identities = 66/246 (26%), Positives = 116/246 (47%), Gaps = 6/246 (2%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISN 585
KV+++T A+ FA+EGA V N +KL + + G + ++
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK---YPGIQTRVL------ 57
Query: 584 DEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLA 405
D K + Q + +LDVL N AG G++L + +D N+R++ L+
Sbjct: 58 DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEE-KDWDFSMNLNVRSMYLMIKAF 116
Query: 404 APHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIIS 228
P ++ K GNIIN+SS+ ++ + Y KA++ T+ +A + +G+R N +
Sbjct: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176
Query: 227 PG----PVLTDIIENSDN-QISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSN 63
PG P L + I+ N + + + F + EIA L ++LASD++ +TG+
Sbjct: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESTYVTGNP 236
Query: 62 YVSDNG 45
+ D G
Sbjct: 237 VIIDGG 242
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 80.6 bits (190), Expect = 6e-15
Identities = 66/246 (26%), Positives = 116/246 (47%), Gaps = 6/246 (2%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISN 585
KV+++T A+ FA+EGA V N +KL + + G + ++
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK---YPGIQTRVL------ 57
Query: 584 DEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLA 405
D K + Q + +LDVL N AG G++L + +D N+R++ L+
Sbjct: 58 DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEE-KDWDFSMNLNVRSMYLMIKAF 116
Query: 404 APHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIIS 228
P ++ K GNIIN+SS+ ++ + Y KA++ T+ +A + +G+R N +
Sbjct: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176
Query: 227 PG----PVLTDIIENSDN-QISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSN 63
PG P L + I+ N + + + F + EIA L ++LASD++ +TG+
Sbjct: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236
Query: 62 YVSDNG 45
+ D G
Sbjct: 237 VIIDGG 242
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 80.2 bits (189), Expect = 8e-15
Identities = 66/246 (26%), Positives = 115/246 (46%), Gaps = 6/246 (2%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISN 585
KV+++T A+ FA+EGA V N +KL + + G + ++
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK---YPGIQTRVL------ 57
Query: 584 DEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLA 405
D K + Q +LDVL N AG G++L + +D N+R++ L+
Sbjct: 58 DVTKKKQIDQFASEVERLDVLFNVAGFVHHGTVLDCEE-KDWDFSMNLNVRSMYLMIKAF 116
Query: 404 APHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIIS 228
P ++ K GNIIN+SS+ ++ + Y KA++ T+ +A + +G+R N +
Sbjct: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNCVC 176
Query: 227 PG----PVLTDIIENSDN-QISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSN 63
PG P L + I+ N + + + F + EIA L ++LASD++ +TG+
Sbjct: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236
Query: 62 YVSDNG 45
+ D G
Sbjct: 237 VIIDGG 242
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 79.8 bits (188), Expect = 1e-14
Identities = 66/246 (26%), Positives = 115/246 (46%), Gaps = 6/246 (2%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISN 585
KV+++T A+ FA+EGA V N +KL + + G + ++
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK---YPGIQTRVL------ 57
Query: 584 DEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLA 405
D K + Q +LDVL N AG G++L + +D N+R++ L+
Sbjct: 58 DVTKKKQIDQFASEVERLDVLFNVAGFVHHGTVLDCEE-KDWDFSMNLNVRSMYLMIKAF 116
Query: 404 APHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIIS 228
P ++ K GNIIN+SS+ ++ + Y KA++ T+ +A + +G+R N +
Sbjct: 117 LPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSLAADFIQQGIRCNCVC 176
Query: 227 PG----PVLTDIIENSDN-QISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSN 63
PG P L + I+ N + + + F + EIA L ++LASD++ +TG+
Sbjct: 177 PGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIAMLCVYLASDESAYVTGNP 236
Query: 62 YVSDNG 45
+ D G
Sbjct: 237 VIIDGG 242
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 79.4 bits (187), Expect = 1e-14
Identities = 64/207 (30%), Positives = 99/207 (47%), Gaps = 8/207 (3%)
Frame = -3
Query: 779 MSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTK--LDNVARECAQVGKKPLI 606
M KV LVT A +GA VA+V N+ A + +K L
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
I+ D+++ ++ + ++ +D FG+LD+L+NNAG+N ++++ NL +V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE---------KNWEKTLQINLVSV 111
Query: 425 ILITSLAAPHLIETKGN----IINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIAL--E 264
I T L ++ + G IIN+SS+ G M P+ YC K + FTR AL
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLM-PVAQQPVYCASKHGIVGFTRSAALAAN 170
Query: 263 LAPRGVRANIISPGPVLTDIIENSDNQ 183
L GVR N I PG V T I+E+ + +
Sbjct: 171 LMNSGVRLNAICPGFVNTAILESIEKE 197
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 79.4 bits (187), Expect = 1e-14
Identities = 64/207 (30%), Positives = 99/207 (47%), Gaps = 8/207 (3%)
Frame = -3
Query: 779 MSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTK--LDNVARECAQVGKKPLI 606
M KV LVT A +GA VA+V N+ A + +K L
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
I+ D+++ ++ + ++ +D FG+LD+L+NNAG+N ++++ NL +V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE---------KNWEKTLQINLVSV 111
Query: 425 ILITSLAAPHLIETKGN----IINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIAL--E 264
I T L ++ + G IIN+SS+ G M P+ YC K + FTR AL
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLM-PVAQQPVYCASKHGIVGFTRSAALAAN 170
Query: 263 LAPRGVRANIISPGPVLTDIIENSDNQ 183
L GVR N I PG V T I+E+ + +
Sbjct: 171 LMNSGVRLNAICPGFVNTAILESIEKE 197
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 78.6 bits (185), Expect = 2e-14
Identities = 64/207 (30%), Positives = 98/207 (47%), Gaps = 8/207 (3%)
Frame = -3
Query: 779 MSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTK--LDNVARECAQVGKKPLI 606
M KV LVT A +GA VA+V N+ A +K L
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLF 60
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
I+ D+++ ++ + ++ +D FG+LD+L+NNAG+N ++++ NL +V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE---------KNWEKTLQINLVSV 111
Query: 425 ILITSLAAPHLIETKGN----IINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIAL--E 264
I T L ++ + G IIN+SS+ G M P+ YC K + FTR AL
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLM-PVAQQPVYCASKHGIVGFTRSAALAAN 170
Query: 263 LAPRGVRANIISPGPVLTDIIENSDNQ 183
L GVR N I PG V T I+E+ + +
Sbjct: 171 LMNSGVRLNAICPGFVNTAILESIEKE 197
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 78.6 bits (185), Expect = 2e-14
Identities = 64/207 (30%), Positives = 98/207 (47%), Gaps = 8/207 (3%)
Frame = -3
Query: 779 MSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTK--LDNVARECAQVGKKPLI 606
M KV LVT A +GA VA+V N+ A +K L
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLF 60
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
I+ D+++ ++ + ++ +D FG+LD+L+NNAG+N ++++ NL +V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE---------KNWEKTLQINLVSV 111
Query: 425 ILITSLAAPHLIETKGN----IINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIAL--E 264
I T L ++ + G IIN+SS+ G M P+ YC K + FTR AL
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLM-PVAQQPVYCASKHGIVGFTRSAALAAN 170
Query: 263 LAPRGVRANIISPGPVLTDIIENSDNQ 183
L GVR N I PG V T I+E+ + +
Sbjct: 171 LMNSGVRLNAICPGFVNTAILESIEKE 197
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 77.0 bits (181), Expect = 8e-14
Identities = 66/248 (26%), Positives = 115/248 (46%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIKADI 591
+KV +T A F + G I R++ ++ AR+ A G++ L + D+
Sbjct: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLL--AGNL-LESYDAVTATNLRAVIL 420
V Q + FG++D+LIN A +G+ L AG L ++ V +
Sbjct: 88 RAPPAVMAAVDQALKEFGRIDILINCA----AGNFLCPAGALSFNAFKTVMDIDTSGTFN 143
Query: 419 ITSLAAPHLIETKGNII-NVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVR 243
++ + G +I N+++ G A KA+++ TR +A+E P+ +R
Sbjct: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGS-AKAAVDAMTRHLAVEWGPQNIR 202
Query: 242 ANIISPGPVL-TDIIENSDN-QISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
N ++PGP+ T+ + Q S A+ L++LG +EIA +L+LAS A +TG
Sbjct: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262
Query: 68 SNYVSDNG 45
+ V+D G
Sbjct: 263 AVLVADGG 270
>AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 77.0 bits (181), Expect = 8e-14
Identities = 66/248 (26%), Positives = 115/248 (46%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIKADI 591
+KV +T A F + G I R++ ++ AR+ A G++ L + D+
Sbjct: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLL--AGNL-LESYDAVTATNLRAVIL 420
V Q + FG++D+LIN A +G+ L AG L ++ V +
Sbjct: 88 RAPPAVMAAVDQALKEFGRIDILINCA----AGNFLCPAGALSFNAFKTVMDIDTSGTFN 143
Query: 419 ITSLAAPHLIETKGNII-NVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVR 243
++ + G +I N+++ G A KA+++ TR +A+E P+ +R
Sbjct: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGS-AKAAVDAMTRHLAVEWGPQNIR 202
Query: 242 ANIISPGPVL-TDIIENSDN-QISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
N ++PGP+ T+ + Q S A+ L++LG +EIA +L+LAS A +TG
Sbjct: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262
Query: 68 SNYVSDNG 45
+ V+D G
Sbjct: 263 AVLVADGG 270
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 77.0 bits (181), Expect = 8e-14
Identities = 66/248 (26%), Positives = 115/248 (46%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIKADI 591
+KV +T A F + G I R++ ++ AR+ A G++ L + D+
Sbjct: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLL--AGNL-LESYDAVTATNLRAVIL 420
V Q + FG++D+LIN A +G+ L AG L ++ V +
Sbjct: 88 RAPPAVMAAVDQALKEFGRIDILINCA----AGNFLCPAGALSFNAFKTVMDIDTSGTFN 143
Query: 419 ITSLAAPHLIETKGNII-NVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVR 243
++ + G +I N+++ G A KA+++ TR +A+E P+ +R
Sbjct: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGS-AKAAVDAMTRHLAVEWGPQNIR 202
Query: 242 ANIISPGPVL-TDIIENSDN-QISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
N ++PGP+ T+ + Q S A+ L++LG +EIA +L+LAS A +TG
Sbjct: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262
Query: 68 SNYVSDNG 45
+ V+D G
Sbjct: 263 AVLVADGG 270
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 77.0 bits (181), Expect = 8e-14
Identities = 66/248 (26%), Positives = 115/248 (46%), Gaps = 7/248 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIKADI 591
+KV +T A F + G I R++ ++ AR+ A G++ L + D+
Sbjct: 28 DKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDV 87
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLL--AGNL-LESYDAVTATNLRAVIL 420
V Q + FG++D+LIN A +G+ L AG L ++ V +
Sbjct: 88 RAPPAVMAAVDQALKEFGRIDILINCA----AGNFLCPAGALSFNAFKTVMDIDTSGTFN 143
Query: 419 ITSLAAPHLIETKGNII-NVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVR 243
++ + G +I N+++ G A KA+++ TR +A+E P+ +R
Sbjct: 144 VSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGS-AKAAVDAMTRHLAVEWGPQNIR 202
Query: 242 ANIISPGPVL-TDIIENSDN-QISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITG 69
N ++PGP+ T+ + Q S A+ L++LG +EIA +L+LAS A +TG
Sbjct: 203 VNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTG 262
Query: 68 SNYVSDNG 45
+ V+D G
Sbjct: 263 AVLVADGG 270
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 76.2 bits (179), Expect = 1e-13
Identities = 50/181 (27%), Positives = 79/181 (43%), Gaps = 1/181 (0%)
Frame = -3
Query: 770 TNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADI 591
TNKV LVT A A++ A V + R +D G +
Sbjct: 29 TNKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHV 88
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
E+ + +V + G +D+L++NA +N L E +D N++A L+T
Sbjct: 89 GKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALMTK 148
Query: 410 LAAPHLIETKG-NIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANI 234
P + + G +++ VSSI P PGF Y + K +L +A+ELAPR +R N
Sbjct: 149 AVVPEMEKRGGGSVVIVSSIAA-FSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVNC 207
Query: 233 I 231
+
Sbjct: 208 L 208
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 75.4 bits (177), Expect = 2e-13
Identities = 50/170 (29%), Positives = 88/170 (51%), Gaps = 11/170 (6%)
Frame = -3
Query: 521 INNAGMNKSGSLLAGNLLESYDAVTAT----NLRAVILITSLAAPHLIETKG-NIINVSS 357
+ G++ +G++ E + + AT N++A L+T P + + G +++ VSS
Sbjct: 76 LQGEGLSVTGTVCHVGKAEDRERLVATTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSS 135
Query: 356 IGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQIS 177
I P PGF Y + K +L T+ +A+ELAPR +R N ++PG +I+ S +++
Sbjct: 136 IAA-FSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPG-----LIKTSFSRML 189
Query: 176 W------DIFRAATALKKLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
W + + +++LGEP + A ++ FL S+ A ITG V G
Sbjct: 190 WMDKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 239
>BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein.
Length = 244
Score = 73.3 bits (172), Expect = 9e-13
Identities = 61/226 (26%), Positives = 108/226 (47%), Gaps = 7/226 (3%)
Frame = -3
Query: 701 KEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDV 525
+ G I R++ ++ AR+ A G++ L + D+ V Q + FG++D+
Sbjct: 2 RHGCHTVIASRSLPRVLTAARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDI 61
Query: 524 LINNAGMNKSGSLL--AGNL-LESYDAVTATNLRAVILITSLAAPHLIETKGNII-NVSS 357
LIN A +G+ L AG L ++ V + ++ + G +I N+++
Sbjct: 62 LINCA----AGNFLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITA 117
Query: 356 IGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVL-TDIIENSDN-Q 183
G A KA+++ TR +A+E P+ +R N ++PGP+ T+ + Q
Sbjct: 118 TLGNRGQALQVHAGS-AKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQ 176
Query: 182 ISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
S A+ L++LG +EIA +L+LAS A +TG+ V+D G
Sbjct: 177 ASLSTKVTASPLQRLGNKTEIAHSVLYLASPLASYVTGAVLVADGG 222
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 72.5 bits (170), Expect = 2e-12
Identities = 59/240 (24%), Positives = 110/240 (45%), Gaps = 9/240 (3%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARE--CAQVGK----KPLI 606
N VV++T A F GA + + GRN L+ + RE + K KP +
Sbjct: 52 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYL 111
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+ D+++ + + FG +D+L+NNAG++ G+++ ++ V TN
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIM-DTTVDVDKRVMETNYFGP 170
Query: 425 ILITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+ +T P +I+ + G+I+ +SSI G M +P AY K + F + E+
Sbjct: 171 VALTKALLPSMIKRRQGHIVAISSIQGKM-SIPFRSAYAASKHATQAFFDCLRAEMEQYE 229
Query: 248 VRANIISPGPVLTDIIEN--SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSI 75
+ +ISPG + T++ N + + + + TA + P E+A+ +L K + +
Sbjct: 230 IEVTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQGR--SPVEVAQDVLAAVGKKKKDV 287
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 72.5 bits (170), Expect = 2e-12
Identities = 59/240 (24%), Positives = 110/240 (45%), Gaps = 9/240 (3%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARE--CAQVGK----KPLI 606
N VV++T A F GA + + GRN L+ + RE + K KP +
Sbjct: 52 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYL 111
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+ D+++ + + FG +D+L+NNAG++ G+++ ++ V TN
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIM-DTTVDVDKRVMETNYFGP 170
Query: 425 ILITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+ +T P +I+ + G+I+ +SSI G M +P AY K + F + E+
Sbjct: 171 VALTKALLPSMIKRRQGHIVAISSIQGKM-SIPFRSAYAASKHATQAFFDCLRAEMEQYE 229
Query: 248 VRANIISPGPVLTDIIEN--SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSI 75
+ +ISPG + T++ N + + + + TA + P E+A+ +L K + +
Sbjct: 230 IEVTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQGR--SPVEVAQDVLAAVGKKKKDV 287
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 72.5 bits (170), Expect = 2e-12
Identities = 59/240 (24%), Positives = 110/240 (45%), Gaps = 9/240 (3%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARE--CAQVGK----KPLI 606
N VV++T A F GA + + GRN L+ + RE + K KP +
Sbjct: 52 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYL 111
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+ D+++ + + FG +D+L+NNAG++ G+++ ++ V TN
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIM-DTTVDVDKRVMETNYFGP 170
Query: 425 ILITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+ +T P +I+ + G+I+ +SSI G M +P AY K + F + E+
Sbjct: 171 VALTKALLPSMIKRRQGHIVAISSIQGKM-SIPFRSAYAASKHATQAFFDCLRAEMEQYE 229
Query: 248 VRANIISPGPVLTDIIEN--SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSI 75
+ +ISPG + T++ N + + + + TA + P E+A+ +L K + +
Sbjct: 230 IEVTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQGR--SPVEVAQDVLAAVGKKKKDV 287
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 72.5 bits (170), Expect = 2e-12
Identities = 59/240 (24%), Positives = 110/240 (45%), Gaps = 9/240 (3%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARE--CAQVGK----KPLI 606
N VV++T A F GA + + GRN L+ + RE + K KP +
Sbjct: 37 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYL 96
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+ D+++ + + FG +D+L+NNAG++ G+++ ++ V TN
Sbjct: 97 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIM-DTTVDVDKRVMETNYFGP 155
Query: 425 ILITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+ +T P +I+ + G+I+ +SSI G M +P AY K + F + E+
Sbjct: 156 VALTKALLPSMIKRRQGHIVAISSIQGKM-SIPFRSAYAASKHATQAFFDCLRAEMEQYE 214
Query: 248 VRANIISPGPVLTDIIEN--SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSI 75
+ +ISPG + T++ N + + + + TA + P E+A+ +L K + +
Sbjct: 215 IEVTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQGR--SPVEVAQDVLAAVGKKKKDV 272
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 71.7 bits (168), Expect = 3e-12
Identities = 61/238 (25%), Positives = 113/238 (47%), Gaps = 10/238 (4%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII--KAD 594
+++ LVT A ++G V R V ++ +A EC G +I + D
Sbjct: 11 DRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCD 70
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
+SN+E+ ++ +D+ INNAG+ + +LL+G+ + + N+ A+ + T
Sbjct: 71 LSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGS-TSGWKDMFNVNVLALSICT 129
Query: 413 SLAAPHLIETK---GNIINVSSIGG-TMVPMPGFLAYCMGKASLNHFTRGIALEL--APR 252
A + E G+IIN++S+ G ++P+ Y K ++ T G+ EL A
Sbjct: 130 REAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQT 189
Query: 251 GVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG--EPSEIAELMLFLASDKA 84
+RA ISPG V T ++ D +AA +++ +P ++AE ++++ S A
Sbjct: 190 HIRATCISPGVVETQFAFKLHDK---DPEKAAATYEQMKCLKPEDVAEAVIYVLSTPA 244
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 71.7 bits (168), Expect = 3e-12
Identities = 61/238 (25%), Positives = 113/238 (47%), Gaps = 10/238 (4%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII--KAD 594
+++ LVT A ++G V R V ++ +A EC G +I + D
Sbjct: 11 DRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIPYRCD 70
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
+SN+E+ ++ +D+ INNAG+ + +LL+G+ + + N+ A+ + T
Sbjct: 71 LSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGS-TSGWKDMFNVNVLALSICT 129
Query: 413 SLAAPHLIETK---GNIINVSSIGG-TMVPMPGFLAYCMGKASLNHFTRGIALEL--APR 252
A + E G+IIN++S+ G ++P+ Y K ++ T G+ EL A
Sbjct: 130 REAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQT 189
Query: 251 GVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG--EPSEIAELMLFLASDKA 84
+RA ISPG V T ++ D +AA +++ +P ++AE ++++ S A
Sbjct: 190 HIRATCISPGVVETQFAFKLHDK---DPEKAAATYEQMKCLKPEDVAEAVIYVLSTPA 244
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 71.7 bits (168), Expect = 3e-12
Identities = 52/199 (26%), Positives = 94/199 (47%), Gaps = 7/199 (3%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARE--CAQVGK----KPLI 606
N VV++T A F GA + + GRN L+ + RE + K KP +
Sbjct: 57 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYL 116
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
+ D+++ + + FG +D+L+NNAG++ G+++ ++ V TN
Sbjct: 117 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIM-DTTVDVDKRVMETNYFGP 175
Query: 425 ILITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+ +T P +I+ + G+I+ +SSI G M +P AY K + F + E+
Sbjct: 176 VALTKALLPSMIKRRQGHIVAISSIQGKM-SIPFRSAYAASKHATQAFFDCLRAEMEQYE 234
Query: 248 VRANIISPGPVLTDIIENS 192
+ +ISPG + T++ N+
Sbjct: 235 IEVTVISPGYIHTNLSVNA 253
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 70.1 bits (164), Expect = 9e-12
Identities = 45/162 (27%), Positives = 81/162 (50%), Gaps = 1/162 (0%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDV 525
A++G +A++ RN L+ +G L D++ + + + ++ G+++
Sbjct: 23 ARKGYRLAVIARN---LEGAKAAAGDLGGDHLAFSCDVAKEHDVQNTFEEMEKHLGRVNF 79
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKG-NIINVSSIGG 348
L+N AG+N+ G LL E + TNL +L A +I+ +G +I+NV SI G
Sbjct: 80 LVNAAGINRDG-LLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQGGSIVNVGSIVG 138
Query: 347 TMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
+ G Y K L F+R +A E+A + +R N+++PG
Sbjct: 139 -LKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPG 179
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 69.7 bits (163), Expect = 1e-11
Identities = 58/195 (29%), Positives = 88/195 (45%), Gaps = 10/195 (5%)
Frame = -3
Query: 779 MSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAI---------VGRNVTKLDNVARECAQ 627
+ F +VVLVT A+ FA+ GA V + VG+ D V E +
Sbjct: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
Query: 626 VGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVT 447
G K + A+ + EE + +V+ +DAFG++DV++NNAG+ + S A E +D +
Sbjct: 65 RGGKAV---ANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRS-FARISDEDWDIIH 120
Query: 446 ATNLRAVILITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIA 270
+LR +T A H+ + K G II SS G G Y K L +A
Sbjct: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNF-GQANYSAAKLGLLGLANSLA 179
Query: 269 LELAPRGVRANIISP 225
+E + N I+P
Sbjct: 180 IEGRKSNIHCNTIAP 194
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 69.7 bits (163), Expect = 1e-11
Identities = 58/195 (29%), Positives = 88/195 (45%), Gaps = 10/195 (5%)
Frame = -3
Query: 779 MSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAI---------VGRNVTKLDNVARECAQ 627
+ F +VVLVT A+ FA+ GA V + VG+ D V E +
Sbjct: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
Query: 626 VGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVT 447
G K + A+ + EE + +V+ +DAFG++DV++NNAG+ + S A E +D +
Sbjct: 65 RGGKAV---ANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRS-FARISDEDWDIIH 120
Query: 446 ATNLRAVILITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIA 270
+LR +T A H+ + K G II SS G G Y K L +A
Sbjct: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNF-GQANYSAAKLGLLGLANSLA 179
Query: 269 LELAPRGVRANIISP 225
+E + N I+P
Sbjct: 180 IEGRKSNIHCNTIAP 194
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 69.7 bits (163), Expect = 1e-11
Identities = 58/195 (29%), Positives = 88/195 (45%), Gaps = 10/195 (5%)
Frame = -3
Query: 779 MSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAI---------VGRNVTKLDNVARECAQ 627
+ F +VVLVT A+ FA+ GA V + VG+ D V E +
Sbjct: 5 LRFDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR 64
Query: 626 VGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVT 447
G K + A+ + EE + +V+ +DAFG++DV++NNAG+ + S A E +D +
Sbjct: 65 RGGKAV---ANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRS-FARISDEDWDIIH 120
Query: 446 ATNLRAVILITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIA 270
+LR +T A H+ + K G II SS G G Y K L +A
Sbjct: 121 RVHLRGSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNF-GQANYSAAKLGLLGLANSLA 179
Query: 269 LELAPRGVRANIISP 225
+E + N I+P
Sbjct: 180 IEGRKSNIHCNTIAP 194
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 67.3 bits (157), Expect = 6e-11
Identities = 55/232 (23%), Positives = 97/232 (41%), Gaps = 4/232 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S ++VL+T FAK + + + N ++ A EC ++G
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN EE + Q G + +++NNAG LL+ E N+ I
Sbjct: 93 DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLS-TKDEEITKTFEVNILGHFWI 151
Query: 416 TSLAAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALE---LAPRG 249
T P ++E G+I+ V+S+ G +P + YC K + F RG+ E L G
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCG-HEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 248 VRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLAS 93
++ + + P V T +N ++ W + ++ L + + M+F++S
Sbjct: 211 IKTSCLCPVFVNTGFTKNPSTRL-WPVLETDEVVRSLIDGILTNKKMIFVSS 261
>AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 66.9 bits (156), Expect = 8e-11
Identities = 58/207 (28%), Positives = 100/207 (48%), Gaps = 7/207 (3%)
Frame = -3
Query: 644 ARECA-QVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLL--AGN 474
AR+ A G++ L + D+ V Q + FG++D+LIN A +G+ L AG
Sbjct: 57 ARKLAGATGRRCLPLSMDVRAPPAVMAAVDQALKEFGRIDILINCA----AGNFLCPAGA 112
Query: 473 L-LESYDAVTATNLRAVILITSLAAPHLIETKGNII-NVSSIGGTMVPMPGFLAYCMGKA 300
L ++ V + ++ + G +I N+++ G A KA
Sbjct: 113 LSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGS-AKA 171
Query: 299 SLNHFTRGIALELAPRGVRANIISPGPVL-TDIIENSDN-QISWDIFRAATALKKLGEPS 126
+++ TR +A+E P+ +R N ++PGP+ T+ + Q S A+ L++LG +
Sbjct: 172 AVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQASLSTKVTASPLQRLGNKT 231
Query: 125 EIAELMLFLASDKARSITGSNYVSDNG 45
EIA +L+LAS A +TG+ V+D G
Sbjct: 232 EIAHSVLYLASPLASYVTGAVLVADGG 258
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 66.5 bits (155), Expect = 1e-10
Identities = 55/232 (23%), Positives = 96/232 (41%), Gaps = 4/232 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S ++VL+T FAK + + + N ++ A EC ++G
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN EE + Q G + +++NNAG LL+ E N+ I
Sbjct: 93 DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLS-TKDEEITKTFEVNILGHFWI 151
Query: 416 TSLAAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALE---LAPRG 249
T P ++E G+I+ V+S+ G +P + YC K + F RG+ E L G
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCG-HEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 248 VRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLAS 93
++ + + P V T +N ++ W + ++ L + + M+F+ S
Sbjct: 211 IKTSCLCPVFVNTGFTKNPSTRL-WPVLETDEVVRSLIDGILTNKKMIFVPS 261
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 66.5 bits (155), Expect = 1e-10
Identities = 55/232 (23%), Positives = 96/232 (41%), Gaps = 4/232 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S ++VL+T FAK + + + N ++ A EC ++G
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN EE + Q G + +++NNAG LL+ E N+ I
Sbjct: 93 DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLS-TKDEEITKTFEVNILGHFWI 151
Query: 416 TSLAAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALE---LAPRG 249
T P ++E G+I+ V+S+ G +P + YC K + F RG+ E L G
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCG-HEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 248 VRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLAS 93
++ + + P V T +N ++ W + ++ L + + M+F+ S
Sbjct: 211 IKTSCLCPVFVNTGFTKNPSTRL-WPVLETDEVVRSLIDGILTNKKMIFVPS 261
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 66.5 bits (155), Expect = 1e-10
Identities = 52/183 (28%), Positives = 87/183 (47%), Gaps = 6/183 (3%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADISNDEEAKTIVQQTIDAFGKLD 528
A G ++ ++ RN KL VA++ A K II AD S+ E +++ + +
Sbjct: 88 ASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKD-KDVG 146
Query: 527 VLINNAGMNKSGSLLAGNLLES--YDAVTATNLRAVILITSLAAPHLIETK-GNIINVSS 357
+L+NN G+ L E +D + N+ A L+ + P ++E K G I+ +SS
Sbjct: 147 ILVNNVGVFYPYPQYFTQLSEDKLWDIINV-NIAAASLMVHVVLPGMVERKKGAIVTISS 205
Query: 356 IGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSD--NQ 183
G P P A+ KA L+HF+R + E A +G+ + P V T + S+ ++
Sbjct: 206 -GSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHR 264
Query: 182 ISW 174
SW
Sbjct: 265 CSW 267
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 66.5 bits (155), Expect = 1e-10
Identities = 55/232 (23%), Positives = 96/232 (41%), Gaps = 4/232 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S ++VL+T FAK + + + N ++ A EC ++G
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN EE + Q G + +++NNAG LL+ E N+ I
Sbjct: 93 DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLS-TKDEEITKTFEVNILGHFWI 151
Query: 416 TSLAAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALE---LAPRG 249
T P ++E G+I+ V+S+ G +P + YC K + F RG+ E L G
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCG-HEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 248 VRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLAS 93
++ + + P V T +N ++ W + ++ L + + M+F+ S
Sbjct: 211 IKTSCLCPVFVNTGFTKNPSTRL-WPVLETDEVVRSLIDGILTNKKMIFVPS 261
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 66.5 bits (155), Expect = 1e-10
Identities = 55/232 (23%), Positives = 96/232 (41%), Gaps = 4/232 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S ++VL+T FAK + + + N ++ A EC ++G
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN EE + Q G + +++NNAG LL+ E N+ I
Sbjct: 93 DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLS-TKDEEITKTFEVNILGHFWI 151
Query: 416 TSLAAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALE---LAPRG 249
T P ++E G+I+ V+S+ G +P + YC K + F RG+ E L G
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCG-HEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 248 VRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLAS 93
++ + + P V T +N ++ W + ++ L + + M+F+ S
Sbjct: 211 IKTSCLCPVFVNTGFTKNPSTRL-WPVLETDEVVRSLIDGILTNKKMIFVPS 261
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 66.5 bits (155), Expect = 1e-10
Identities = 52/183 (28%), Positives = 87/183 (47%), Gaps = 6/183 (3%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADISNDEEAKTIVQQTIDAFGKLD 528
A G ++ ++ RN KL VA++ A K II AD S+ E +++ + +
Sbjct: 67 ASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKD-KDVG 125
Query: 527 VLINNAGMNKSGSLLAGNLLES--YDAVTATNLRAVILITSLAAPHLIETK-GNIINVSS 357
+L+NN G+ L E +D + N+ A L+ + P ++E K G I+ +SS
Sbjct: 126 ILVNNVGVFYPYPQYFTQLSEDKLWDIINV-NIAAASLMVHVVLPGMVERKKGAIVTISS 184
Query: 356 IGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSD--NQ 183
G P P A+ KA L+HF+R + E A +G+ + P V T + S+ ++
Sbjct: 185 -GSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHR 243
Query: 182 ISW 174
SW
Sbjct: 244 CSW 246
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 66.5 bits (155), Expect = 1e-10
Identities = 52/183 (28%), Positives = 87/183 (47%), Gaps = 6/183 (3%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADISNDEEAKTIVQQTIDAFGKLD 528
A G ++ ++ RN KL VA++ A K II AD S+ E +++ + +
Sbjct: 88 ASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKD-KDVG 146
Query: 527 VLINNAGMNKSGSLLAGNLLES--YDAVTATNLRAVILITSLAAPHLIETK-GNIINVSS 357
+L+NN G+ L E +D + N+ A L+ + P ++E K G I+ +SS
Sbjct: 147 ILVNNVGVFYPYPQYFTQLSEDKLWDIINV-NIAAASLMVHVVLPGMVERKKGAIVTISS 205
Query: 356 IGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSD--NQ 183
G P P A+ KA L+HF+R + E A +G+ + P V T + S+ ++
Sbjct: 206 -GSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHR 264
Query: 182 ISW 174
SW
Sbjct: 265 CSW 267
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 66.5 bits (155), Expect = 1e-10
Identities = 52/183 (28%), Positives = 87/183 (47%), Gaps = 6/183 (3%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADISNDEEAKTIVQQTIDAFGKLD 528
A G ++ ++ RN KL VA++ A K II AD S+ E +++ + +
Sbjct: 67 ASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKD-KDVG 125
Query: 527 VLINNAGMNKSGSLLAGNLLES--YDAVTATNLRAVILITSLAAPHLIETK-GNIINVSS 357
+L+NN G+ L E +D + N+ A L+ + P ++E K G I+ +SS
Sbjct: 126 ILVNNVGVFYPYPQYFTQLSEDKLWDIINV-NIAAASLMVHVVLPGMVERKKGAIVTISS 184
Query: 356 IGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSD--NQ 183
G P P A+ KA L+HF+R + E A +G+ + P V T + S+ ++
Sbjct: 185 -GSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHR 243
Query: 182 ISW 174
SW
Sbjct: 244 CSW 246
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 66.5 bits (155), Expect = 1e-10
Identities = 55/232 (23%), Positives = 96/232 (41%), Gaps = 4/232 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S ++VL+T FAK + + + N ++ A EC ++G
Sbjct: 33 SVAGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVTAHAYVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN EE + Q G + +++NNAG LL+ E N+ I
Sbjct: 93 DCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLS-TKDEEITKTFEVNILGHFWI 151
Query: 416 TSLAAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALE---LAPRG 249
T P ++E G+I+ V+S+ G +P + YC K + F RG+ E L G
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCG-HEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTG 210
Query: 248 VRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLAS 93
++ + + P V T +N ++ W + ++ L + + M+F+ S
Sbjct: 211 IKTSCLCPVFVNTGFTKNPSTRL-WPVLETDEVVRSLIDGILTNKKMIFVPS 261
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 65.3 bits (152), Expect = 2e-10
Identities = 51/183 (27%), Positives = 87/183 (47%), Gaps = 6/183 (3%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADISNDEEAKTIVQQTIDAFGKLD 528
A G ++ ++ RN KL VA++ A K II AD S+ E +++ + +
Sbjct: 88 ASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKD-KDVG 146
Query: 527 VLINNAGMNKSGSLLAGNLLES--YDAVTATNLRAVILITSLAAPHLIETK-GNIINVSS 357
+L+NN G+ L E +D + N+ A L+ + P ++E K G I+ +SS
Sbjct: 147 ILVNNVGVFYPYPQYFTQLSEDKLWDIINV-NIAAASLMVHVVLPGMVERKKGAIVTISS 205
Query: 356 IGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSD--NQ 183
G P P A+ +A L+HF+R + E A +G+ + P V T + S+ ++
Sbjct: 206 -GSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHR 264
Query: 182 ISW 174
SW
Sbjct: 265 CSW 267
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 65.3 bits (152), Expect = 2e-10
Identities = 51/183 (27%), Positives = 87/183 (47%), Gaps = 6/183 (3%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADISNDEEAKTIVQQTIDAFGKLD 528
A G ++ ++ RN KL VA++ A K II AD S+ E +++ + +
Sbjct: 88 ASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKD-KDVG 146
Query: 527 VLINNAGMNKSGSLLAGNLLES--YDAVTATNLRAVILITSLAAPHLIETK-GNIINVSS 357
+L+NN G+ L E +D + N+ A L+ + P ++E K G I+ +SS
Sbjct: 147 ILVNNVGVFYPYPQYFTQLSEDKLWDIINV-NIAAASLMVHVVLPGMVERKKGAIVTISS 205
Query: 356 IGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSD--NQ 183
G P P A+ +A L+HF+R + E A +G+ + P V T + S+ ++
Sbjct: 206 -GSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSLIPFYVATSMTAPSNFLHR 264
Query: 182 ISW 174
SW
Sbjct: 265 CSW 267
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 65.3 bits (152), Expect = 2e-10
Identities = 54/203 (26%), Positives = 87/203 (42%), Gaps = 4/203 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S T ++VL+T A FAK + + + N L+ A +C +G K
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN E+ + ++ G + +L+NNAG+ + L A + N+ A
Sbjct: 93 DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFA-TQDPQIEKTFEVNVLAHFWT 151
Query: 416 TSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP---RG 249
T P + + G+I+ V+S G V +P LAYC K + F + + ELA G
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAG-HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITG 210
Query: 248 VRANIISPGPVLTDIIENSDNQI 180
V+ + P V T I+N +
Sbjct: 211 VKTTCLCPNFVNTGFIKNPSTSL 233
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 65.3 bits (152), Expect = 2e-10
Identities = 54/203 (26%), Positives = 87/203 (42%), Gaps = 4/203 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S T ++VL+T A FAK + + + N L+ A +C +G K
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN E+ + ++ G + +L+NNAG+ + L A + N+ A
Sbjct: 93 DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFA-TQDPQIEKTFEVNVLAHFWT 151
Query: 416 TSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP---RG 249
T P + + G+I+ V+S G V +P LAYC K + F + + ELA G
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAG-HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITG 210
Query: 248 VRANIISPGPVLTDIIENSDNQI 180
V+ + P V T I+N +
Sbjct: 211 VKTTCLCPNFVNTGFIKNPSTSL 233
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 65.3 bits (152), Expect = 2e-10
Identities = 54/203 (26%), Positives = 87/203 (42%), Gaps = 4/203 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S T ++VL+T A FAK + + + N L+ A +C +G K
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN E+ + ++ G + +L+NNAG+ + L A + N+ A
Sbjct: 93 DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFA-TQDPQIEKTFEVNVLAHFWT 151
Query: 416 TSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP---RG 249
T P + + G+I+ V+S G V +P LAYC K + F + + ELA G
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAG-HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITG 210
Query: 248 VRANIISPGPVLTDIIENSDNQI 180
V+ + P V T I+N +
Sbjct: 211 VKTTCLCPNFVNTGFIKNPSTSL 233
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 65.3 bits (152), Expect = 2e-10
Identities = 54/203 (26%), Positives = 87/203 (42%), Gaps = 4/203 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S T ++VL+T A FAK + + + N L+ A +C +G K
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN E+ + ++ G + +L+NNAG+ + L A + N+ A
Sbjct: 93 DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFA-TQDPQIEKTFEVNVLAHFWT 151
Query: 416 TSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP---RG 249
T P + + G+I+ V+S G V +P LAYC K + F + + ELA G
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAG-HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITG 210
Query: 248 VRANIISPGPVLTDIIENSDNQI 180
V+ + P V T I+N +
Sbjct: 211 VKTTCLCPNFVNTGFIKNPSTSL 233
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 65.3 bits (152), Expect = 2e-10
Identities = 54/203 (26%), Positives = 87/203 (42%), Gaps = 4/203 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S T ++VL+T A FAK + + + N L+ A +C +G K
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN E+ + ++ G + +L+NNAG+ + L A + N+ A
Sbjct: 93 DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFA-TQDPQIEKTFEVNVLAHFWT 151
Query: 416 TSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP---RG 249
T P + + G+I+ V+S G V +P LAYC K + F + + ELA G
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAG-HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITG 210
Query: 248 VRANIISPGPVLTDIIENSDNQI 180
V+ + P V T I+N +
Sbjct: 211 VKTTCLCPNFVNTGFIKNPSTSL 233
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 65.3 bits (152), Expect = 2e-10
Identities = 53/188 (28%), Positives = 84/188 (44%), Gaps = 4/188 (2%)
Frame = -3
Query: 785 DVMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGK-KPL 609
D S VL+T A H+A+ G+ + + L V C ++G K
Sbjct: 23 DPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVF 82
Query: 608 IIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDA---VTATN 438
I AD+++ E +++VQ +D G LD L+ +N G AG S A + N
Sbjct: 83 YIAADMASPEAPESVVQFALDKLGGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVN 138
Query: 437 LRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELA 258
+ + +TS A P L ++KG+++ VSS+ G VP Y K +L+ F + EL
Sbjct: 139 FVSYVQLTSRALPSLTDSKGSLVVVSSLLG-RVPTSFSTPYSAAKFALDGFFGSLRRELD 197
Query: 257 PRGVRANI 234
+ V I
Sbjct: 198 VQDVNVAI 205
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 65.3 bits (152), Expect = 2e-10
Identities = 53/188 (28%), Positives = 84/188 (44%), Gaps = 4/188 (2%)
Frame = -3
Query: 785 DVMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGK-KPL 609
D S VL+T A H+A+ G+ + + L V C ++G K
Sbjct: 23 DPASLQGARVLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKVF 82
Query: 608 IIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDA---VTATN 438
I AD+++ E +++VQ +D G LD L+ +N G AG S A + N
Sbjct: 83 YIAADMASPEAPESVVQFALDKLGGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVN 138
Query: 437 LRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELA 258
+ + +TS A P L ++KG+++ VSS+ G VP Y K +L+ F + EL
Sbjct: 139 FVSYVQLTSRALPSLTDSKGSLVVVSSLLG-RVPTSFSTPYSAAKFALDGFFGSLRRELD 197
Query: 257 PRGVRANI 234
+ V I
Sbjct: 198 VQDVNVAI 205
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 65.3 bits (152), Expect = 2e-10
Identities = 54/203 (26%), Positives = 87/203 (42%), Gaps = 4/203 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S T ++VL+T A FAK + + + N L+ A +C +G K
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN E+ + ++ G + +L+NNAG+ + L A + N+ A
Sbjct: 93 DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFA-TQDPQIEKTFEVNVLAHFWT 151
Query: 416 TSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP---RG 249
T P + + G+I+ V+S G V +P LAYC K + F + + ELA G
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAG-HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITG 210
Query: 248 VRANIISPGPVLTDIIENSDNQI 180
V+ + P V T I+N +
Sbjct: 211 VKTTCLCPNFVNTGFIKNPSTSL 233
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 65.3 bits (152), Expect = 2e-10
Identities = 54/203 (26%), Positives = 87/203 (42%), Gaps = 4/203 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S T ++VL+T A FAK + + + N L+ A +C +G K
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN E+ + ++ G + +L+NNAG+ + L A + N+ A
Sbjct: 93 DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFA-TQDPQIEKTFEVNVLAHFWT 151
Query: 416 TSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP---RG 249
T P + + G+I+ V+S G V +P LAYC K + F + + ELA G
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAG-HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITG 210
Query: 248 VRANIISPGPVLTDIIENSDNQI 180
V+ + P V T I+N +
Sbjct: 211 VKTTCLCPNFVNTGFIKNPSTSL 233
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 64.9 bits (151), Expect = 3e-10
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 7/210 (3%)
Frame = -3
Query: 797 LHGVDVMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADV--AIVGRNVTKLDNVARECAQV 624
L G +++ K VLVT + + G V ++ N + + R C+
Sbjct: 72 LSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP- 130
Query: 623 GKKPLIIKADISNDEEAKTIVQQTIDAFGK--LDVLINNAGM---NKSGSLLAGNLLESY 459
+ +++ DI+ + K + L +INNAG+ G LL L+ Y
Sbjct: 131 --RLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL---LMTDY 185
Query: 458 DAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTR 279
A N + +T P L ++KG ++NVSS+GG PM +Y KA++ F+
Sbjct: 186 KQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGG-APMERLASYGSSKAAVTMFSS 244
Query: 278 GIALELAPRGVRANIISPGPVLTDIIENSD 189
+ LEL+ G++ I PG LT+I SD
Sbjct: 245 VMRLELSKWGIKVASIQPGGFLTNIAGTSD 274
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 64.9 bits (151), Expect = 3e-10
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 7/210 (3%)
Frame = -3
Query: 797 LHGVDVMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADV--AIVGRNVTKLDNVARECAQV 624
L G +++ K VLVT + + G V ++ N + + R C+
Sbjct: 72 LSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP- 130
Query: 623 GKKPLIIKADISNDEEAKTIVQQTIDAFGK--LDVLINNAGM---NKSGSLLAGNLLESY 459
+ +++ DI+ + K + L +INNAG+ G LL L+ Y
Sbjct: 131 --RLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL---LMTDY 185
Query: 458 DAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTR 279
A N + +T P L ++KG ++NVSS+GG PM +Y KA++ F+
Sbjct: 186 KQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGG-APMERLASYGSSKAAVTMFSS 244
Query: 278 GIALELAPRGVRANIISPGPVLTDIIENSD 189
+ LEL+ G++ I PG LT+I SD
Sbjct: 245 VMRLELSKWGIKVASIQPGGFLTNIAGTSD 274
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 64.9 bits (151), Expect = 3e-10
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 7/210 (3%)
Frame = -3
Query: 797 LHGVDVMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADV--AIVGRNVTKLDNVARECAQV 624
L G +++ K VLVT + + G V ++ N + + R C+
Sbjct: 72 LSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP- 130
Query: 623 GKKPLIIKADISNDEEAKTIVQQTIDAFGK--LDVLINNAGM---NKSGSLLAGNLLESY 459
+ +++ DI+ + K + L +INNAG+ G LL L+ Y
Sbjct: 131 --RLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL---LMTDY 185
Query: 458 DAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTR 279
A N + +T P L ++KG ++NVSS+GG PM +Y KA++ F+
Sbjct: 186 KQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGG-APMERLASYGSSKAAVTMFSS 244
Query: 278 GIALELAPRGVRANIISPGPVLTDIIENSD 189
+ LEL+ G++ I PG LT+I SD
Sbjct: 245 VMRLELSKWGIKVASIQPGGFLTNIAGTSD 274
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 64.9 bits (151), Expect = 3e-10
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 7/210 (3%)
Frame = -3
Query: 797 LHGVDVMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADV--AIVGRNVTKLDNVARECAQV 624
L G +++ K VLVT + + G V ++ N + + R C+
Sbjct: 72 LSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP- 130
Query: 623 GKKPLIIKADISNDEEAKTIVQQTIDAFGK--LDVLINNAGM---NKSGSLLAGNLLESY 459
+ +++ DI+ + K + L +INNAG+ G LL L+ Y
Sbjct: 131 --RLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL---LMTDY 185
Query: 458 DAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTR 279
A N + +T P L ++KG ++NVSS+GG PM +Y KA++ F+
Sbjct: 186 KQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGG-APMERLASYGSSKAAVTMFSS 244
Query: 278 GIALELAPRGVRANIISPGPVLTDIIENSD 189
+ LEL+ G++ I PG LT+I SD
Sbjct: 245 VMRLELSKWGIKVASIQPGGFLTNIAGTSD 274
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 64.9 bits (151), Expect = 3e-10
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 7/210 (3%)
Frame = -3
Query: 797 LHGVDVMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADV--AIVGRNVTKLDNVARECAQV 624
L G +++ K VLVT + + G V ++ N + + R C+
Sbjct: 72 LSGQELLPVDQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP- 130
Query: 623 GKKPLIIKADISNDEEAKTIVQQTIDAFGK--LDVLINNAGM---NKSGSLLAGNLLESY 459
+ +++ DI+ + K + L +INNAG+ G LL L+ Y
Sbjct: 131 --RLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL---LMTDY 185
Query: 458 DAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTR 279
A N + +T P L ++KG ++NVSS+GG PM +Y KA++ F+
Sbjct: 186 KQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGG-APMERLASYGSSKAAVTMFSS 244
Query: 278 GIALELAPRGVRANIISPGPVLTDIIENSD 189
+ LEL+ G++ I PG LT+I SD
Sbjct: 245 VMRLELSKWGIKVASIQPGGFLTNIAGTSD 274
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 64.5 bits (150), Expect = 4e-10
Identities = 51/183 (27%), Positives = 86/183 (46%), Gaps = 6/183 (3%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADISNDEEAKTIVQQTIDAFGKLD 528
A G ++ ++ RN KL VA++ A K II AD S+ E +++ + +
Sbjct: 88 ASRGLNIILISRNEEKLQVVAKDIADTYKVETDIIVADFSSGREIYLPIREALKD-KDVG 146
Query: 527 VLINNAGMNKSGSLLAGNLLES--YDAVTATNLRAVILITSLAAPHLIETK-GNIINVSS 357
+L+NN G+ L E +D + N+ A L+ + P ++E K G I+ +SS
Sbjct: 147 ILVNNVGVFYPYPQYFTQLSEDKLWDIINV-NIAAASLMVHVVLPGMVERKKGAIVTISS 205
Query: 356 IGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSD--NQ 183
G P P A+ KA L+HF+R + E A +G+ + P V + S+ ++
Sbjct: 206 -GSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSLIPFYVAASMTAPSNFLHR 264
Query: 182 ISW 174
SW
Sbjct: 265 CSW 267
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 64.5 bits (150), Expect = 4e-10
Identities = 57/210 (27%), Positives = 93/210 (44%), Gaps = 7/210 (3%)
Frame = -3
Query: 797 LHGVDVMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADV--AIVGRNVTKLDNVARECAQV 624
L G +++ K VLVT + + G V ++ N + + R C+
Sbjct: 72 LSGQELLPADQKAVLVTGGDCGLGHALCKYLDELGFTVFAGVLNENGPGAEELRRTCSP- 130
Query: 623 GKKPLIIKADISNDEEAKTIVQQTIDAFGK--LDVLINNAGM---NKSGSLLAGNLLESY 459
+ +++ DI+ + K + L +INNAG+ G LL L+ Y
Sbjct: 131 --RLSVLQMDITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELL---LMTDY 185
Query: 458 DAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTR 279
A N + +T P L ++KG ++NVSS+GG PM +Y KA++ F+
Sbjct: 186 KQCMAVNFFGTVEVTKTFLPLLRKSKGRLVNVSSMGGG-APMERLASYGSSKAAVTMFSS 244
Query: 278 GIALELAPRGVRANIISPGPVLTDIIENSD 189
+ LEL+ G++ I PG LT+I SD
Sbjct: 245 VMRLELSKWGIKVASIQPGGFLTNIAGTSD 274
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 64.1 bits (149), Expect = 6e-10
Identities = 54/203 (26%), Positives = 86/203 (42%), Gaps = 4/203 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S T + VL+T A FAK + + + N L+ A +C +G K
Sbjct: 33 SVTGETVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN E+ + ++ G + +L+NNAG+ + L A + N+ A
Sbjct: 93 DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFA-TQDPQIEKTFEVNVLAHFWT 151
Query: 416 TSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP---RG 249
T P + + G+I+ V+S G V +P LAYC K + F + + ELA G
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAG-HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITG 210
Query: 248 VRANIISPGPVLTDIIENSDNQI 180
V+ + P V T I+N +
Sbjct: 211 VKTTCLCPNFVNTGFIKNPSTSL 233
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 63.3 bits (147), Expect = 1e-09
Identities = 51/176 (28%), Positives = 82/176 (46%), Gaps = 6/176 (3%)
Frame = -3
Query: 779 MSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTK--LDNVARECAQVGKKPLI 606
M KV LVT A +GA VA+V N+ A + +K L
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
I+ D+++ ++ + ++ +D FG+LD+L+NNAG+N ++++ NL +V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNK---------KNWEKTLQINLVSV 111
Query: 425 ILITSLAAPHLIETKGN----IINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIA 270
I T L ++ + G IIN+SS+ G M P+ YC K + FTR A
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSLAGLM-PVAQQPVYCASKHGIVGFTRSAA 166
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 62.1 bits (144), Expect = 2e-09
Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 4/203 (1%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKA 597
S T ++VL+T A FAK + + + N L+ A +C +G K
Sbjct: 33 SVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKVHTFVV 92
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D SN E+ + + G + +L+NNAG+ + L A + N+ A
Sbjct: 93 DCSNREDIYSSAKNCKAEIGDVSILVNNAGVVYTSDLFA-TQDPQIEKTFEVNVLAHFWT 151
Query: 416 TSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP---RG 249
T P + + G+I+ V+S G V +P LAYC K + F + + ELA G
Sbjct: 152 TKAFLPAMTKNNHGHIVTVASAAG-HVSVPFLLAYCSSKFAAVGFHKTLTDELAALQITG 210
Query: 248 VRANIISPGPVLTDIIENSDNQI 180
V+ + P V T I+ +
Sbjct: 211 VKTTCLCPNFVNTGFIKKMSTSL 233
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/189 (25%), Positives = 89/189 (47%), Gaps = 12/189 (6%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAY 315
LE + V NL + L A + + +G IIN +S+ G AY
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV-AAFEGQVGQAAY 168
Query: 314 CMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG 135
K + T IA +LAP G+R I+PG T ++ + ++ + +LG
Sbjct: 169 SASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLG 228
Query: 134 EPSEIAELM 108
+P+E A L+
Sbjct: 229 DPAEYAHLV 237
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/189 (25%), Positives = 89/189 (47%), Gaps = 12/189 (6%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAY 315
LE + V NL + L A + + +G IIN +S+ G AY
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV-AAFEGQVGQAAY 168
Query: 314 CMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG 135
K + T IA +LAP G+R I+PG T ++ + ++ + +LG
Sbjct: 169 SASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLG 228
Query: 134 EPSEIAELM 108
+P+E A L+
Sbjct: 229 DPAEYAHLV 237
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/189 (25%), Positives = 89/189 (47%), Gaps = 12/189 (6%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAY 315
LE + V NL + L A + + +G IIN +S+ G AY
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV-AAFEGQVGQAAY 168
Query: 314 CMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG 135
K + T IA +LAP G+R I+PG T ++ + ++ + +LG
Sbjct: 169 SASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLG 228
Query: 134 EPSEIAELM 108
+P+E A L+
Sbjct: 229 DPAEYAHLV 237
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/189 (25%), Positives = 89/189 (47%), Gaps = 12/189 (6%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAY 315
LE + V NL + L A + + +G IIN +S+ G AY
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV-AAFEGQVGQAAY 168
Query: 314 CMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG 135
K + T IA +LAP G+R I+PG T ++ + ++ + +LG
Sbjct: 169 SASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLG 228
Query: 134 EPSEIAELM 108
+P+E A L+
Sbjct: 229 DPAEYAHLV 237
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/189 (25%), Positives = 89/189 (47%), Gaps = 12/189 (6%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAY 315
LE + V NL + L A + + +G IIN +S+ G AY
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV-AAFEGQVGQAAY 168
Query: 314 CMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG 135
K + T IA +LAP G+R I+PG T ++ + ++ + +LG
Sbjct: 169 SASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLG 228
Query: 134 EPSEIAELM 108
+P+E A L+
Sbjct: 229 DPAEYAHLV 237
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/189 (25%), Positives = 89/189 (47%), Gaps = 12/189 (6%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAY 315
LE + V NL + L A + + +G IIN +S+ G AY
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV-AAFEGQVGQAAY 168
Query: 314 CMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG 135
K + T IA +LAP G+R I+PG T ++ + ++ + +LG
Sbjct: 169 SASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLG 228
Query: 134 EPSEIAELM 108
+P+E A L+
Sbjct: 229 DPAEYAHLV 237
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/189 (25%), Positives = 89/189 (47%), Gaps = 12/189 (6%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAY 315
LE + V NL + L A + + +G IIN +S+ G AY
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV-AAFEGQVGQAAY 168
Query: 314 CMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG 135
K + T IA +LAP G+R I+PG T ++ + ++ + +LG
Sbjct: 169 SASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLG 228
Query: 134 EPSEIAELM 108
+P+E A L+
Sbjct: 229 DPAEYAHLV 237
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 61.7 bits (143), Expect = 3e-09
Identities = 48/189 (25%), Positives = 89/189 (47%), Gaps = 12/189 (6%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAY 315
LE + V NL + L A + + +G IIN +S+ G AY
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV-AAFEGQVGQAAY 168
Query: 314 CMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG 135
K + T IA +LAP G+R I+PG T ++ + ++ + +LG
Sbjct: 169 SASKGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLG 228
Query: 134 EPSEIAELM 108
+P+E A L+
Sbjct: 229 DPAEYAHLV 237
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 61.3 bits (142), Expect = 4e-09
Identities = 48/186 (25%), Positives = 88/186 (47%), Gaps = 12/186 (6%)
Frame = -3
Query: 629 QVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--NLLE 465
++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G + LE
Sbjct: 3 KLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLE 62
Query: 464 SYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAYCMG 306
+ V NL + L A + + +G IIN +S+ G AY
Sbjct: 63 DFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA-FEGQVGQAAYSAS 121
Query: 305 KASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPS 126
K + T IA +LAP G+R I+PG T ++ + ++ + +LG+P+
Sbjct: 122 KGGIVGMTLPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEKVCNFLASQVPFPSRLGDPA 181
Query: 125 EIAELM 108
E A L+
Sbjct: 182 EYAHLV 187
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 60.5 bits (140), Expect = 7e-09
Identities = 61/250 (24%), Positives = 97/250 (38%), Gaps = 6/250 (2%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIK 600
SF KV +T + GA I R + L A + + Q G K I+
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 599 ADISNDEEAKTIVQQTIDAFGKLDVLINNAGMN--KSGSLLAGNLLESYDAVTATNLRAV 426
D+ + + + V + I G +++INNA N L+ N ++ +T L
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN---AWKTITDIVLNGT 172
Query: 425 ILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLA-YCMGKASLNHFTRGIALELAPRG 249
+T LI+ + +S GF+ KA + ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 248 VRANIISPGPVLT-DIIENSDNQISWD-IFRAATALKKLGEPSEIAELMLFLASDKARSI 75
+R N+I PGP+ T D +++ +LG E+A L FL SD A I
Sbjct: 233 MRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWI 292
Query: 74 TGSNYVSDNG 45
G+ D G
Sbjct: 293 NGAVIKFDGG 302
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 60.5 bits (140), Expect = 7e-09
Identities = 61/250 (24%), Positives = 97/250 (38%), Gaps = 6/250 (2%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIK 600
SF KV +T + GA I R + L A + + Q G K I+
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 599 ADISNDEEAKTIVQQTIDAFGKLDVLINNAGMN--KSGSLLAGNLLESYDAVTATNLRAV 426
D+ + + + V + I G +++INNA N L+ N ++ +T L
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN---AWKTITDIVLNGT 172
Query: 425 ILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLA-YCMGKASLNHFTRGIALELAPRG 249
+T LI+ + +S GF+ KA + ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 248 VRANIISPGPVLT-DIIENSDNQISWD-IFRAATALKKLGEPSEIAELMLFLASDKARSI 75
+R N+I PGP+ T D +++ +LG E+A L FL SD A I
Sbjct: 233 MRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWI 292
Query: 74 TGSNYVSDNG 45
G+ D G
Sbjct: 293 NGAVIKFDGG 302
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 60.5 bits (140), Expect = 7e-09
Identities = 61/250 (24%), Positives = 97/250 (38%), Gaps = 6/250 (2%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIK 600
SF KV +T + GA I R + L A + + Q G K I+
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 599 ADISNDEEAKTIVQQTIDAFGKLDVLINNAGMN--KSGSLLAGNLLESYDAVTATNLRAV 426
D+ + + + V + I G +++INNA N L+ N ++ +T L
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN---AWKTITDIVLNGT 172
Query: 425 ILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLA-YCMGKASLNHFTRGIALELAPRG 249
+T LI+ + +S GF+ KA + ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 248 VRANIISPGPVLT-DIIENSDNQISWD-IFRAATALKKLGEPSEIAELMLFLASDKARSI 75
+R N+I PGP+ T D +++ +LG E+A L FL SD A I
Sbjct: 233 MRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWI 292
Query: 74 TGSNYVSDNG 45
G+ D G
Sbjct: 293 NGAVIKFDGG 302
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 60.5 bits (140), Expect = 7e-09
Identities = 61/250 (24%), Positives = 97/250 (38%), Gaps = 6/250 (2%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIK 600
SF KV +T + GA I R + L A + + Q G K I+
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 599 ADISNDEEAKTIVQQTIDAFGKLDVLINNAGMN--KSGSLLAGNLLESYDAVTATNLRAV 426
D+ + + + V + I G +++INNA N L+ N ++ +T L
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN---AWKTITDIVLNGT 172
Query: 425 ILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLA-YCMGKASLNHFTRGIALELAPRG 249
+T LI+ + +S GF+ KA + ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 248 VRANIISPGPVLT-DIIENSDNQISWD-IFRAATALKKLGEPSEIAELMLFLASDKARSI 75
+R N+I PGP+ T D +++ +LG E+A L FL SD A I
Sbjct: 233 MRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWI 292
Query: 74 TGSNYVSDNG 45
G+ D G
Sbjct: 293 NGAVIKFDGG 302
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 60.5 bits (140), Expect = 7e-09
Identities = 61/250 (24%), Positives = 97/250 (38%), Gaps = 6/250 (2%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIK 600
SF KV +T + GA I R + L A + + Q G K I+
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 599 ADISNDEEAKTIVQQTIDAFGKLDVLINNAGMN--KSGSLLAGNLLESYDAVTATNLRAV 426
D+ + + + V + I G +++INNA N L+ N ++ +T L
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN---AWKTITDIVLNGT 172
Query: 425 ILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLA-YCMGKASLNHFTRGIALELAPRG 249
+T LI+ + +S GF+ KA + ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 248 VRANIISPGPVLT-DIIENSDNQISWD-IFRAATALKKLGEPSEIAELMLFLASDKARSI 75
+R N+I PGP+ T D +++ +LG E+A L FL SD A I
Sbjct: 233 MRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSDYASWI 292
Query: 74 TGSNYVSDNG 45
G+ D G
Sbjct: 293 NGAVIKFDGG 302
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 59.7 bits (138), Expect = 1e-08
Identities = 32/101 (31%), Positives = 54/101 (53%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG++ G + +L E+Y V NL + +T P + KG ++N+SS+ G
Sbjct: 141 LVNNAGISTFGEVEFTSL-ETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGR 199
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
M P YC+ K + F+ + E+ P GV+ +++ PG
Sbjct: 200 MA-NPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 59.7 bits (138), Expect = 1e-08
Identities = 32/101 (31%), Positives = 54/101 (53%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG++ G + +L E+Y V NL + +T P + KG ++N+SS+ G
Sbjct: 141 LVNNAGISTFGEVEFTSL-ETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGR 199
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
M P YC+ K + F+ + E+ P GV+ +++ PG
Sbjct: 200 MA-NPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 59.7 bits (138), Expect = 1e-08
Identities = 52/196 (26%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISN 585
+V +VT A+ K GA V I GR++ L VA+E +G + + + D S
Sbjct: 8 QVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQ 67
Query: 584 DEEAKTIVQQTI-DAFGKLDVLINNAG------MNKSGSLLAGNLLESYDAVTATNLRAV 426
+ E +++ +Q + G+LDVL+NNA +N +D + LR
Sbjct: 68 ESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGH 127
Query: 425 ILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGV 246
+ A ++ +I V S G++ M L Y +GKA+ + A EL GV
Sbjct: 128 YFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVL-YGVGKAACDKLAADCAHELRRHGV 186
Query: 245 RANIISPGPVLTDIIE 198
+ PG V T++++
Sbjct: 187 SCVSLWPGIVQTELLK 202
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 59.7 bits (138), Expect = 1e-08
Identities = 32/101 (31%), Positives = 54/101 (53%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG++ G + +L E+Y V NL + +T P + KG ++N+SS+ G
Sbjct: 141 LVNNAGISTFGEVEFTSL-ETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGR 199
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
M P YC+ K + F+ + E+ P GV+ +++ PG
Sbjct: 200 MA-NPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 59.7 bits (138), Expect = 1e-08
Identities = 32/101 (31%), Positives = 54/101 (53%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG++ G + +L E+Y V NL + +T P + KG ++N+SS+ G
Sbjct: 141 LVNNAGISTFGEVEFTSL-ETYKQVAEVNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGR 199
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
M P YC+ K + F+ + E+ P GV+ +++ PG
Sbjct: 200 MA-NPARSPYCITKFGVEAFSDCLRYEMYPLGVKVSVVEPG 239
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 58.4 bits (135), Expect = 3e-08
Identities = 51/196 (26%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISN 585
+V +VT A+ K GA V I GR++ L VA+E +G + + + D S
Sbjct: 8 QVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQ 67
Query: 584 DEEAKTIVQQTI-DAFGKLDVLINNAG------MNKSGSLLAGNLLESYDAVTATNLRAV 426
+ E +++ +Q + G+LDVL+NNA +N +D + LR
Sbjct: 68 ESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGH 127
Query: 425 ILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGV 246
+ A ++ +I V S G++ M + Y +GKA+ + A EL GV
Sbjct: 128 YFCSVYGARLMVPAGQGLIVVISSPGSLQYMFN-VPYGVGKAACDKLAADCAHELRRHGV 186
Query: 245 RANIISPGPVLTDIIE 198
+ PG V T++++
Sbjct: 187 SCVSLWPGIVQTELLK 202
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 58.4 bits (135), Expect = 3e-08
Identities = 51/196 (26%), Positives = 87/196 (44%), Gaps = 7/196 (3%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISN 585
+V +VT A+ K GA V I GR++ L VA+E +G + + + D S
Sbjct: 8 QVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQ 67
Query: 584 DEEAKTIVQQTI-DAFGKLDVLINNAG------MNKSGSLLAGNLLESYDAVTATNLRAV 426
+ E +++ +Q + G+LDVL+NNA +N +D + LR
Sbjct: 68 ESEVRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGH 127
Query: 425 ILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGV 246
+ A ++ +I V S G++ M + Y +GKA+ + A EL GV
Sbjct: 128 YFCSVYGARLMVPAGQGLIVVISSPGSLQYMFN-VPYGVGKAACDKLAADCAHELRRHGV 186
Query: 245 RANIISPGPVLTDIIE 198
+ PG V T++++
Sbjct: 187 SCVSLWPGIVQTELLK 202
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 4/143 (2%)
Frame = -3
Query: 596 DISNDEEAKTIVQQTIDAFGK--LDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVI 423
D++ E K Q D G+ L L+NNAG+ + + V NL +I
Sbjct: 79 DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLI 138
Query: 422 LITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVR 243
+T P + +G ++N+SS GG + + G YC+ K + F+ I EL GV+
Sbjct: 139 EVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG--GYCVSKFGVEAFSDSIRRELYYFGVK 196
Query: 242 ANIISPGPVLTDII--ENSDNQI 180
II PG T I+ EN ++++
Sbjct: 197 VCIIEPGNYRTAILGKENLESRM 219
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 4/143 (2%)
Frame = -3
Query: 596 DISNDEEAKTIVQQTIDAFGK--LDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVI 423
D++ E K Q D G+ L L+NNAG+ + + V NL +I
Sbjct: 79 DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLI 138
Query: 422 LITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVR 243
+T P + +G ++N+SS GG + + G YC+ K + F+ I EL GV+
Sbjct: 139 EVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG--GYCVSKFGVEAFSDSIRRELYYFGVK 196
Query: 242 ANIISPGPVLTDII--ENSDNQI 180
II PG T I+ EN ++++
Sbjct: 197 VCIIEPGNYRTAILGKENLESRM 219
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 57.6 bits (133), Expect = 5e-08
Identities = 42/143 (29%), Positives = 67/143 (46%), Gaps = 4/143 (2%)
Frame = -3
Query: 596 DISNDEEAKTIVQQTIDAFGK--LDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVI 423
D++ E K Q D G+ L L+NNAG+ + + V NL +I
Sbjct: 79 DVTKSESIKAAAQWVRDKVGEQGLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLI 138
Query: 422 LITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVR 243
+T P + +G ++N+SS GG + + G YC+ K + F+ I EL GV+
Sbjct: 139 EVTLHMLPMVKRARGRVVNMSSSGGRVAVIGG--GYCVSKFGVEAFSDSIRRELYYFGVK 196
Query: 242 ANIISPGPVLTDII--ENSDNQI 180
II PG T I+ EN ++++
Sbjct: 197 VCIIEPGNYRTAILGKENLESRM 219
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 57.2 bits (132), Expect = 7e-08
Identities = 59/250 (23%), Positives = 96/250 (38%), Gaps = 6/250 (2%)
Frame = -3
Query: 776 SFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGKKPLIIK 600
SF KV +T + GA I R + L A + + Q G K I+
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQ 115
Query: 599 ADISNDEEAKTIVQQTIDAFGKLDVLINNAGMN--KSGSLLAGNLLESYDAVTATNLRAV 426
D+ + + + V + I G +++INNA N L+ N ++ +T L
Sbjct: 116 CDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSPN---AWKTITDIVLNGT 172
Query: 425 ILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLA-YCMGKASLNHFTRGIALELAPRG 249
+T LI+ + +S GF+ KA + ++ +A E G
Sbjct: 173 AFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAEWGKYG 232
Query: 248 VRANIISPGPVLT-DIIENSDNQISWD-IFRAATALKKLGEPSEIAELMLFLASDKARSI 75
+R N+I PGP+ T D +++ +LG E+A L FL S A +
Sbjct: 233 MRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELANLAAFLCSGYASWV 292
Query: 74 TGSNYVSDNG 45
G+ D G
Sbjct: 293 NGAVIKFDGG 302
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 56.8 bits (131), Expect = 9e-08
Identities = 50/193 (25%), Positives = 85/193 (44%), Gaps = 7/193 (3%)
Frame = -3
Query: 755 LVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEE 576
+VT A+ K GA V I GR++ L VA+E +G + + + D S + E
Sbjct: 11 VVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVPVVCDSSQESE 70
Query: 575 AKTIVQQTI-DAFGKLDVLINNAG------MNKSGSLLAGNLLESYDAVTATNLRAVILI 417
+++ +Q + G+LDVL+NNA +N +D + LR
Sbjct: 71 VRSLFEQVDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRGHYFC 130
Query: 416 TSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRAN 237
+ A ++ +I V S G++ M + Y +GKA+ + A EL GV
Sbjct: 131 SVYGARLMVPAGQGLIVVISSPGSLQYMFN-VPYGVGKAACDKLAADCAHELRRHGVSCV 189
Query: 236 IISPGPVLTDIIE 198
+ PG V T++++
Sbjct: 190 SLWPGIVQTELLK 202
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 56.0 bits (129), Expect = 2e-07
Identities = 45/184 (24%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQ--VGKKPLI--IKADI 591
V+VT A+ K+GA + +V RN KL +E + K ++ I D+
Sbjct: 35 VVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDV 94
Query: 590 SND-EEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
S D + + +++Q + G +D+L+N AGM SG + +++ + + N + +
Sbjct: 95 SQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGK-FEDLEVSTFERLMSINYLGSVYPS 153
Query: 413 SLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRAN 237
+ E + G I+ VSS G + + GF AY K ++ + +E+ P V
Sbjct: 154 RAVITTMKERRVGRIVFVSSQAG-QLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYIT 212
Query: 236 IISP 225
+ P
Sbjct: 213 VAYP 216
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 56.0 bits (129), Expect = 2e-07
Identities = 45/184 (24%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQ--VGKKPLI--IKADI 591
V+VT A+ K+GA + +V RN KL +E + K ++ I D+
Sbjct: 35 VVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDV 94
Query: 590 SND-EEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
S D + + +++Q + G +D+L+N AGM SG + +++ + + N + +
Sbjct: 95 SQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGK-FEDLEVSTFERLMSINYLGSVYPS 153
Query: 413 SLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRAN 237
+ E + G I+ VSS G + + GF AY K ++ + +E+ P V
Sbjct: 154 RAVITTMKERRVGRIVFVSSQAG-QLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYIT 212
Query: 236 IISP 225
+ P
Sbjct: 213 VAYP 216
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/197 (24%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 782 VMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII 603
+ T+K + +T A F K+G V + +T+ + A + A+ ++ +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGFHV--IAACLTESGSTALK-AETSERLRTV 80
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDV--LINNAGMNKSGSLLAGNLLESYDAVTATNLRA 429
D+++ E K Q + G+ + LINNAG+ + LE Y NL
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFG 140
Query: 428 VILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+I +T P + + +G +INVSS+GG + + G Y K ++ F + ++ G
Sbjct: 141 LISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG--GYTPSKYAVEGFNDSLRRDMKAFG 198
Query: 248 VRANIISPGPVLTDIIE 198
V + I PG T++ +
Sbjct: 199 VHVSCIEPGLFKTNLAD 215
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 56.0 bits (129), Expect = 2e-07
Identities = 45/184 (24%), Positives = 83/184 (45%), Gaps = 6/184 (3%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQ--VGKKPLI--IKADI 591
V+VT A+ K+GA + +V RN KL +E + K ++ I D+
Sbjct: 35 VVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDV 94
Query: 590 SND-EEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILIT 414
S D + + +++Q + G +D+L+N AGM SG + +++ + + N + +
Sbjct: 95 SQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGK-FEDLEVSTFERLMSINYLGSVYPS 153
Query: 413 SLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRAN 237
+ E + G I+ VSS G + + GF AY K ++ + +E+ P V
Sbjct: 154 RAVITTMKERRVGRIVFVSSQAG-QLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYIT 212
Query: 236 IISP 225
+ P
Sbjct: 213 VAYP 216
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/197 (24%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 782 VMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII 603
+ T+K + +T A F K+G V + +T+ + A + A+ ++ +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGFHV--IAACLTESGSTALK-AETSERLRTV 80
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDV--LINNAGMNKSGSLLAGNLLESYDAVTATNLRA 429
D+++ E K Q + G+ + LINNAG+ + LE Y NL
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFG 140
Query: 428 VILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+I +T P + + +G +INVSS+GG + + G Y K ++ F + ++ G
Sbjct: 141 LISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG--GYTPSKYAVEGFNDSLRRDMKAFG 198
Query: 248 VRANIISPGPVLTDIIE 198
V + I PG T++ +
Sbjct: 199 VHVSCIEPGLFKTNLAD 215
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/197 (24%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 782 VMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII 603
+ T+K + +T A F K+G V + +T+ + A + A+ ++ +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGFHV--IAACLTESGSTALK-AETSERLRTV 80
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDV--LINNAGMNKSGSLLAGNLLESYDAVTATNLRA 429
D+++ E K Q + G+ + LINNAG+ + LE Y NL
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFG 140
Query: 428 VILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+I +T P + + +G +INVSS+GG + + G Y K ++ F + ++ G
Sbjct: 141 LISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG--GYTPSKYAVEGFNDSLRRDMKAFG 198
Query: 248 VRANIISPGPVLTDIIE 198
V + I PG T++ +
Sbjct: 199 VHVSCIEPGLFKTNLAD 215
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/197 (24%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 782 VMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII 603
+ T+K + +T A F K+G V + +T+ + A + A+ ++ +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGFHV--IAACLTESGSTALK-AETSERLRTV 80
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDV--LINNAGMNKSGSLLAGNLLESYDAVTATNLRA 429
D+++ E K Q + G+ + LINNAG+ + LE Y NL
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFG 140
Query: 428 VILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+I +T P + + +G +INVSS+GG + + G Y K ++ F + ++ G
Sbjct: 141 LISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG--GYTPSKYAVEGFNDSLRRDMKAFG 198
Query: 248 VRANIISPGPVLTDIIE 198
V + I PG T++ +
Sbjct: 199 VHVSCIEPGLFKTNLAD 215
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/197 (24%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 782 VMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII 603
+ T+K + +T A F K+G V + +T+ + A + A+ ++ +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGFHV--IAACLTESGSTALK-AETSERLRTV 80
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDV--LINNAGMNKSGSLLAGNLLESYDAVTATNLRA 429
D+++ E K Q + G+ + LINNAG+ + LE Y NL
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFG 140
Query: 428 VILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+I +T P + + +G +INVSS+GG + + G Y K ++ F + ++ G
Sbjct: 141 LISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG--GYTPSKYAVEGFNDSLRRDMKAFG 198
Query: 248 VRANIISPGPVLTDIIE 198
V + I PG T++ +
Sbjct: 199 VHVSCIEPGLFKTNLAD 215
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/197 (24%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 782 VMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII 603
+ T+K + +T A F K+G V + +T+ + A + A+ ++ +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGFHV--IAACLTESGSTALK-AETSERLRTV 80
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDV--LINNAGMNKSGSLLAGNLLESYDAVTATNLRA 429
D+++ E K Q + G+ + LINNAG+ + LE Y NL
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFG 140
Query: 428 VILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+I +T P + + +G +INVSS+GG + + G Y K ++ F + ++ G
Sbjct: 141 LISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG--GYTPSKYAVEGFNDSLRRDMKAFG 198
Query: 248 VRANIISPGPVLTDIIE 198
V + I PG T++ +
Sbjct: 199 VHVSCIEPGLFKTNLAD 215
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/197 (24%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 782 VMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII 603
+ T+K + +T A F K+G V + +T+ + A + A+ ++ +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGFHV--IAACLTESGSTALK-AETSERLRTV 80
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDV--LINNAGMNKSGSLLAGNLLESYDAVTATNLRA 429
D+++ E K Q + G+ + LINNAG+ + LE Y NL
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFG 140
Query: 428 VILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+I +T P + + +G +INVSS+GG + + G Y K ++ F + ++ G
Sbjct: 141 LISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG--GYTPSKYAVEGFNDSLRRDMKAFG 198
Query: 248 VRANIISPGPVLTDIIE 198
V + I PG T++ +
Sbjct: 199 VHVSCIEPGLFKTNLAD 215
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/197 (24%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 782 VMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII 603
+ T+K + +T A F K+G V + +T+ + A + A+ ++ +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGFHV--IAACLTESGSTALK-AETSERLRTV 80
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDV--LINNAGMNKSGSLLAGNLLESYDAVTATNLRA 429
D+++ E K Q + G+ + LINNAG+ + LE Y NL
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFG 140
Query: 428 VILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+I +T P + + +G +INVSS+GG + + G Y K ++ F + ++ G
Sbjct: 141 LISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG--GYTPSKYAVEGFNDSLRRDMKAFG 198
Query: 248 VRANIISPGPVLTDIIE 198
V + I PG T++ +
Sbjct: 199 VHVSCIEPGLFKTNLAD 215
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 56.0 bits (129), Expect = 2e-07
Identities = 44/171 (25%), Positives = 81/171 (47%), Gaps = 3/171 (1%)
Frame = -3
Query: 710 HFAKEGADVAIVGRNVTKLDNVARECAQ-VGKKPLIIKADISNDEEAKTIVQQTIDAF-G 537
H K+ V R++ K + + + +G+ + + D+ +DE V Q + G
Sbjct: 27 HDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDVCSDES----VAQCLSCIQG 82
Query: 536 KLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETK-GNIINVS 360
++DVL+NNAGM G L G L + V TN + + P + + G+I+ +S
Sbjct: 83 EVDVLVNNAGMGLVGP-LEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVIS 141
Query: 359 SIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTD 207
S+ G + + Y K +L F +A++L + +++ PGPV+T+
Sbjct: 142 SVMGLQGVIFNDV-YAASKFALEGFFESLAIQLLQFNIFISLVEPGPVVTE 191
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 56.0 bits (129), Expect = 2e-07
Identities = 48/197 (24%), Positives = 88/197 (44%), Gaps = 2/197 (1%)
Frame = -3
Query: 782 VMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII 603
+ T+K + +T A F K+G V + +T+ + A + A+ ++ +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGFHV--IAACLTESGSTALK-AETSERLRTV 80
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDV--LINNAGMNKSGSLLAGNLLESYDAVTATNLRA 429
D+++ E K Q + G+ + LINNAG+ + LE Y NL
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFG 140
Query: 428 VILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+I +T P + + +G +INVSS+GG + + G Y K ++ F + ++ G
Sbjct: 141 LISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG--GYTPSKYAVEGFNDSLRRDMKAFG 198
Query: 248 VRANIISPGPVLTDIIE 198
V + I PG T++ +
Sbjct: 199 VHVSCIEPGLFKTNLAD 215
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 54.8 bits (126), Expect = 4e-07
Identities = 66/253 (26%), Positives = 107/253 (42%), Gaps = 15/253 (5%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQV--GKKPLIIKADI 591
KVV+VT A A+ GA V + R+V K + VA+E ++ L+ K D+
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDL 101
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
S+ + + + + L VLINNAG+ + ++ N L+T
Sbjct: 102 SDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP---YSKTADGFEMHIGVNHLGHFLLTH 158
Query: 410 LAAPHLIET-KGNIINVSSIG------------GTMVPMPGFLAYCMGKASLNHFTRGIA 270
L L E+ I+NVSS+ G G LAYC K + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAG-LAYCHSKLANILFTQELA 217
Query: 269 LELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASD 90
L GV + PG V ++++ +S + + W + + +K P + A+ L A
Sbjct: 218 RRLKGSGVTTYSVHPGTVQSELVRHS-SFMRWMWWLFSFFIK---TPQQGAQTSLHCALT 273
Query: 89 KARSITGSNYVSD 51
+ I N+ SD
Sbjct: 274 EGLEILSGNHFSD 286
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 54.8 bits (126), Expect = 4e-07
Identities = 66/253 (26%), Positives = 107/253 (42%), Gaps = 15/253 (5%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQV--GKKPLIIKADI 591
KVV+VT A A+ GA V + R+V K + VA+E ++ L+ K D+
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDL 101
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
S+ + + + + L VLINNAG+ + ++ N L+T
Sbjct: 102 SDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP---YSKTADGFEMHIGVNHLGHFLLTH 158
Query: 410 LAAPHLIET-KGNIINVSSIG------------GTMVPMPGFLAYCMGKASLNHFTRGIA 270
L L E+ I+NVSS+ G G LAYC K + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAG-LAYCHSKLANILFTQELA 217
Query: 269 LELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASD 90
L GV + PG V ++++ +S + + W + + +K P + A+ L A
Sbjct: 218 RRLKGSGVTTYSVHPGTVQSELVRHS-SFMRWMWWLFSFFIK---TPQQGAQTSLHCALT 273
Query: 89 KARSITGSNYVSD 51
+ I N+ SD
Sbjct: 274 EGLEILSGNHFSD 286
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 54.8 bits (126), Expect = 4e-07
Identities = 66/253 (26%), Positives = 107/253 (42%), Gaps = 15/253 (5%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQV--GKKPLIIKADI 591
KVV+VT A A+ GA V + R+V K + VA+E ++ L+ K D+
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDL 101
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
S+ + + + + L VLINNAG+ + ++ N L+T
Sbjct: 102 SDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP---YSKTADGFEMHIGVNHLGHFLLTH 158
Query: 410 LAAPHLIET-KGNIINVSSIG------------GTMVPMPGFLAYCMGKASLNHFTRGIA 270
L L E+ I+NVSS+ G G LAYC K + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAG-LAYCHSKLANILFTQELA 217
Query: 269 LELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASD 90
L GV + PG V ++++ +S + + W + + +K P + A+ L A
Sbjct: 218 RRLKGSGVTTYSVHPGTVQSELVRHS-SFMRWMWWLFSFFIK---TPQQGAQTSLHCALT 273
Query: 89 KARSITGSNYVSD 51
+ I N+ SD
Sbjct: 274 EGLEILSGNHFSD 286
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 54.8 bits (126), Expect = 4e-07
Identities = 58/216 (26%), Positives = 93/216 (43%), Gaps = 16/216 (7%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP--LIIKADI 591
KVV++T A A GA V I R+V K ++ A E K L+ K D+
Sbjct: 40 KVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDL 99
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
S+ + + + + +L +LINNAG+ + E++ V N L+T
Sbjct: 100 SDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGV---NHLGHFLLTY 156
Query: 410 LAAPHL-IETKGNIINVSSIGGTMVPMP------------GFLAYCMGKASLNHFTRGIA 270
L L + ++NVSS+ + +P GF AYC K + FTR +A
Sbjct: 157 LLLEQLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGF-AYCHSKLANVLFTRELA 215
Query: 269 LELAPRGVRANIISPGPVLTDIIENSDNQ-ISWDIF 165
L GV + PG V ++++ +S + W +F
Sbjct: 216 KRLQGTGVTTYAVHPGVVRSELVRHSSLLCLLWRLF 251
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 54.8 bits (126), Expect = 4e-07
Identities = 51/189 (26%), Positives = 88/189 (46%), Gaps = 5/189 (2%)
Frame = -3
Query: 755 LVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGK-KPLIIKADISNDE 579
+VT A AK G V ++ R+ KLD V+ E + K + I D ++++
Sbjct: 54 VVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASED 113
Query: 578 EAKTIVQQTIDAFGKLDVLINNAGMNKSGS---LLAGNLLESYDAVTATNLRAVILITSL 408
I +T A ++ +L+NN GM+ L +L + N+ +V +T L
Sbjct: 114 IYDKI--KTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQL 171
Query: 407 AAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANII 231
P ++E +KG I+N+SS G M+P+P Y K ++ F++ + E +GV +
Sbjct: 172 VLPGMVERSKGAILNISS-GSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSV 230
Query: 230 SPGPVLTDI 204
P V T +
Sbjct: 231 LPYFVATKL 239
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 54.8 bits (126), Expect = 4e-07
Identities = 66/253 (26%), Positives = 107/253 (42%), Gaps = 15/253 (5%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQV--GKKPLIIKADI 591
KVV+VT A A+ GA V + R+V K + VA+E ++ L+ K D+
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDL 101
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
S+ + + + + L VLINNAG+ + ++ N L+T
Sbjct: 102 SDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP---YSKTADGFEMHIGVNHLGHFLLTH 158
Query: 410 LAAPHLIET-KGNIINVSSIG------------GTMVPMPGFLAYCMGKASLNHFTRGIA 270
L L E+ I+NVSS+ G G LAYC K + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAG-LAYCHSKLANILFTQELA 217
Query: 269 LELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASD 90
L GV + PG V ++++ +S + + W + + +K P + A+ L A
Sbjct: 218 RRLKGSGVTTYSVHPGTVQSELVRHS-SFMRWMWWLFSFFIK---TPQQGAQTSLHCALT 273
Query: 89 KARSITGSNYVSD 51
+ I N+ SD
Sbjct: 274 EGLEILSGNHFSD 286
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 54.8 bits (126), Expect = 4e-07
Identities = 66/253 (26%), Positives = 107/253 (42%), Gaps = 15/253 (5%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQV--GKKPLIIKADI 591
KVV+VT A A+ GA V + R+V K + VA+E ++ L+ K D+
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDL 101
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
S+ + + + + L VLINNAG+ + ++ N L+T
Sbjct: 102 SDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP---YSKTADGFEMHIGVNHLGHFLLTH 158
Query: 410 LAAPHLIET-KGNIINVSSIG------------GTMVPMPGFLAYCMGKASLNHFTRGIA 270
L L E+ I+NVSS+ G G LAYC K + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAG-LAYCHSKLANILFTQELA 217
Query: 269 LELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASD 90
L GV + PG V ++++ +S + + W + + +K P + A+ L A
Sbjct: 218 RRLKGSGVTTYSVHPGTVQSELVRHS-SFMRWMWWLFSFFIK---TPQQGAQTSLHCALT 273
Query: 89 KARSITGSNYVSD 51
+ I N+ SD
Sbjct: 274 EGLEILSGNHFSD 286
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 54.8 bits (126), Expect = 4e-07
Identities = 51/189 (26%), Positives = 88/189 (46%), Gaps = 5/189 (2%)
Frame = -3
Query: 755 LVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGK-KPLIIKADISNDE 579
+VT A AK G V ++ R+ KLD V+ E + K + I D ++++
Sbjct: 54 VVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKFKVETRTIAVDFASED 113
Query: 578 EAKTIVQQTIDAFGKLDVLINNAGMNKSGS---LLAGNLLESYDAVTATNLRAVILITSL 408
I +T A ++ +L+NN GM+ L +L + N+ +V +T L
Sbjct: 114 IYDKI--KTGLAGLEIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMTQL 171
Query: 407 AAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANII 231
P ++E +KG I+N+SS G M+P+P Y K ++ F++ + E +GV +
Sbjct: 172 VLPGMVERSKGAILNISS-GSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQSV 230
Query: 230 SPGPVLTDI 204
P V T +
Sbjct: 231 LPYFVATKL 239
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 54.8 bits (126), Expect = 4e-07
Identities = 58/216 (26%), Positives = 93/216 (43%), Gaps = 16/216 (7%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKP--LIIKADI 591
KVV++T A A GA V I R+V K ++ A E K L+ K D+
Sbjct: 40 KVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVRKLDL 99
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
S+ + + + + +L +LINNAG+ + E++ V N L+T
Sbjct: 100 SDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGV---NHLGHFLLTY 156
Query: 410 LAAPHL-IETKGNIINVSSIGGTMVPMP------------GFLAYCMGKASLNHFTRGIA 270
L L + ++NVSS+ + +P GF AYC K + FTR +A
Sbjct: 157 LLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGF-AYCHSKLANVLFTRELA 215
Query: 269 LELAPRGVRANIISPGPVLTDIIENSDNQ-ISWDIF 165
L GV + PG V ++++ +S + W +F
Sbjct: 216 KRLQGTGVTTYAVHPGVVRSELVRHSSLLCLLWRLF 251
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 54.8 bits (126), Expect = 4e-07
Identities = 66/253 (26%), Positives = 107/253 (42%), Gaps = 15/253 (5%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQV--GKKPLIIKADI 591
KVV+VT A A+ GA V + R+V K + VA+E ++ L+ K D+
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDL 101
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
S+ + + + + L VLINNAG+ + ++ N L+T
Sbjct: 102 SDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP---YSKTADGFEMHIGVNHLGHFLLTH 158
Query: 410 LAAPHLIET-KGNIINVSSIG------------GTMVPMPGFLAYCMGKASLNHFTRGIA 270
L L E+ I+NVSS+ G G LAYC K + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAG-LAYCHSKLANILFTQELA 217
Query: 269 LELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASD 90
L GV + PG V ++++ +S + + W + + +K P + A+ L A
Sbjct: 218 RRLKGSGVTTYSVHPGTVQSELVRHS-SFMRWMWWLFSFFIK---TPQQGAQTSLHCALT 273
Query: 89 KARSITGSNYVSD 51
+ I N+ SD
Sbjct: 274 EGLEILSGNHFSD 286
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 54.8 bits (126), Expect = 4e-07
Identities = 66/253 (26%), Positives = 107/253 (42%), Gaps = 15/253 (5%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQV--GKKPLIIKADI 591
KVV+VT A A+ GA V + R+V K + VA+E ++ L+ K D+
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDL 101
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
S+ + + + + L VLINNAG+ + ++ N L+T
Sbjct: 102 SDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP---YSKTADGFEMHIGVNHLGHFLLTH 158
Query: 410 LAAPHLIET-KGNIINVSSIG------------GTMVPMPGFLAYCMGKASLNHFTRGIA 270
L L E+ I+NVSS+ G G LAYC K + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAG-LAYCHSKLANILFTQELA 217
Query: 269 LELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASD 90
L GV + PG V ++++ +S + + W + + +K P + A+ L A
Sbjct: 218 RRLKGSGVTTYSVHPGTVQSELVRHS-SFMRWMWWLFSFFIK---TPQQGAQTSLHCALT 273
Query: 89 KARSITGSNYVSD 51
+ I N+ SD
Sbjct: 274 EGLEILSGNHFSD 286
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 54.8 bits (126), Expect = 4e-07
Identities = 66/253 (26%), Positives = 107/253 (42%), Gaps = 15/253 (5%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQV--GKKPLIIKADI 591
KVV+VT A A+ GA V + R+V K + VA+E ++ L+ K D+
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDL 101
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
S+ + + + + L VLINNAG+ + ++ N L+T
Sbjct: 102 SDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCP---YSKTADGFEMHIGVNHLGHFLLTH 158
Query: 410 LAAPHLIET-KGNIINVSSIG------------GTMVPMPGFLAYCMGKASLNHFTRGIA 270
L L E+ I+NVSS+ G G LAYC K + FT+ +A
Sbjct: 159 LLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAG-LAYCHSKLANILFTQELA 217
Query: 269 LELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASD 90
L GV + PG V ++++ +S + + W + + +K P + A+ L A
Sbjct: 218 RRLKGSGVTTYSVHPGTVQSELVRHS-SFMRWMWWLFSFFIK---TPQQGAQTSLHCALT 273
Query: 89 KARSITGSNYVSD 51
+ I N+ SD
Sbjct: 274 EGLEILSGNHFSD 286
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/193 (25%), Positives = 82/193 (42%), Gaps = 6/193 (3%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGA-DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISND 582
VL+T A FA+ GA + + GR L E Q+G + D+ N
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNR 100
Query: 581 EEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGN---LLESYDAVTATNLRAVILITS 411
EE + + G + +L+NNA + SL+ + LL+S N T
Sbjct: 101 EEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQH----INTLGQFWTTK 156
Query: 410 LAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RGVRAN 237
P ++E + G+I+ ++S+ + +PG + YC KAS F + L L GV A
Sbjct: 157 AFLPRMLELQNGHIVCLNSV-LALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSAT 215
Query: 236 IISPGPVLTDIIE 198
+ P T++ +
Sbjct: 216 TVLPFHTSTEMFQ 228
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/193 (25%), Positives = 82/193 (42%), Gaps = 6/193 (3%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGA-DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISND 582
VL+T A FA+ GA + + GR L E Q+G + D+ N
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNR 100
Query: 581 EEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGN---LLESYDAVTATNLRAVILITS 411
EE + + G + +L+NNA + SL+ + LL+S N T
Sbjct: 101 EEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQH----INTLGQFWTTK 156
Query: 410 LAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RGVRAN 237
P ++E + G+I+ ++S+ + +PG + YC KAS F + L L GV A
Sbjct: 157 AFLPRMLELQNGHIVCLNSV-LALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSAT 215
Query: 236 IISPGPVLTDIIE 198
+ P T++ +
Sbjct: 216 TVLPFHTSTEMFQ 228
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/193 (25%), Positives = 82/193 (42%), Gaps = 6/193 (3%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGA-DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISND 582
VL+T A FA+ GA + + GR L E Q+G + D+ N
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNR 100
Query: 581 EEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGN---LLESYDAVTATNLRAVILITS 411
EE + + G + +L+NNA + SL+ + LL+S N T
Sbjct: 101 EEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQH----INTLGQFWTTK 156
Query: 410 LAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RGVRAN 237
P ++E + G+I+ ++S+ + +PG + YC KAS F + L L GV A
Sbjct: 157 AFLPRMLELQNGHIVCLNSV-LALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSAT 215
Query: 236 IISPGPVLTDIIE 198
+ P T++ +
Sbjct: 216 TVLPFHTSTEMFQ 228
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/193 (25%), Positives = 82/193 (42%), Gaps = 6/193 (3%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGA-DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISND 582
VL+T A FA+ GA + + GR L E Q+G + D+ N
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNR 100
Query: 581 EEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGN---LLESYDAVTATNLRAVILITS 411
EE + + G + +L+NNA + SL+ + LL+S N T
Sbjct: 101 EEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQH----INTLGQFWTTK 156
Query: 410 LAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RGVRAN 237
P ++E + G+I+ ++S+ + +PG + YC KAS F + L L GV A
Sbjct: 157 AFLPRMLELQNGHIVCLNSV-LALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSAT 215
Query: 236 IISPGPVLTDIIE 198
+ P T++ +
Sbjct: 216 TVLPFHTSTEMFQ 228
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/193 (25%), Positives = 82/193 (42%), Gaps = 6/193 (3%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGA-DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISND 582
VL+T A FA+ GA + + GR L E Q+G + D+ N
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNR 100
Query: 581 EEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGN---LLESYDAVTATNLRAVILITS 411
EE + + G + +L+NNA + SL+ + LL+S N T
Sbjct: 101 EEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQH----INTLGQFWTTK 156
Query: 410 LAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RGVRAN 237
P ++E + G+I+ ++S+ + +PG + YC KAS F + L L GV A
Sbjct: 157 AFLPRMLELQNGHIVCLNSV-LALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSAT 215
Query: 236 IISPGPVLTDIIE 198
+ P T++ +
Sbjct: 216 TVLPFHTSTEMFQ 228
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 52.4 bits (120), Expect = 2e-06
Identities = 50/193 (25%), Positives = 82/193 (42%), Gaps = 6/193 (3%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGA-DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISND 582
VL+T A FA+ GA + + GR L E Q+G + D+ N
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMGTECHYFICDVGNR 100
Query: 581 EEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGN---LLESYDAVTATNLRAVILITS 411
EE + + G + +L+NNA + SL+ + LL+S N T
Sbjct: 101 EEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQH----INTLGQFWTTK 156
Query: 410 LAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-RGVRAN 237
P ++E + G+I+ ++S+ + +PG + YC KAS F + L L GV A
Sbjct: 157 AFLPRMLELQNGHIVCLNSV-LALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSAT 215
Query: 236 IISPGPVLTDIIE 198
+ P T++ +
Sbjct: 216 TVLPFHTSTEMFQ 228
>CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein.
Length = 181
Score = 51.2 bits (117), Expect = 4e-06
Identities = 44/158 (27%), Positives = 81/158 (51%), Gaps = 8/158 (5%)
Frame = -3
Query: 533 LDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETK---GNIINV 363
+D+ INNAG+ + +LL+G+ + + N+ A+ + T A + E G+IIN+
Sbjct: 12 VDICINNAGLARPDTLLSGS-TSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIINI 70
Query: 362 SSIGG-TMVPMPGFLAYCMGKASLNHFTRGIALEL--APRGVRANIISPGPVLTDIIENS 192
+S+ G ++P+ Y K ++ T G+ EL A +RA ISPG V T
Sbjct: 71 NSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKL 130
Query: 191 DNQISWDIFRAATALKKLG--EPSEIAELMLFLASDKA 84
++ D +AA +++ +P ++AE ++++ S A
Sbjct: 131 HDK---DPEKAAATYEQMKCLKPEDVAEAVIYVLSTPA 165
>AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22543 fis, clone HSI00212. ).
Length = 181
Score = 51.2 bits (117), Expect = 4e-06
Identities = 44/158 (27%), Positives = 81/158 (51%), Gaps = 8/158 (5%)
Frame = -3
Query: 533 LDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETK---GNIINV 363
+D+ INNAG+ + +LL+G+ + + N+ A+ + T A + E G+IIN+
Sbjct: 12 VDICINNAGLARPDTLLSGS-TSGWKDMFNVNVLALSICTREAYQSMKERNVDDGHIINI 70
Query: 362 SSIGG-TMVPMPGFLAYCMGKASLNHFTRGIALEL--APRGVRANIISPGPVLTDIIENS 192
+S+ G ++P+ Y K ++ T G+ EL A +RA ISPG V T
Sbjct: 71 NSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQELREAQTHIRATCISPGVVETQFAFKL 130
Query: 191 DNQISWDIFRAATALKKLG--EPSEIAELMLFLASDKA 84
++ D +AA +++ +P ++AE ++++ S A
Sbjct: 131 HDK---DPEKAAATYEQMKCLKPEDVAEAVIYVLSTPA 165
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 50.8 bits (116), Expect = 6e-06
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 9/174 (5%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTK-------LDNVARECAQVGKKPLIIK 600
V +T A+ AK+GA++ I + + A E VG K L
Sbjct: 13 VFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCI 72
Query: 599 ADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVIL 420
D+ ++++ V++ I FG +D+L+NNA + L + D + N R L
Sbjct: 73 VDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTL-DTPTKRLDLMMNVNTRGTYL 131
Query: 419 ITSLAAPHLIETK-GNIINVS-SIGGTMVPMPGFLAYCMGKASLNHFTRGIALE 264
+ P+L ++K +I+N+S + V AY + K ++ + G+A E
Sbjct: 132 ASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEE 185
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 50.8 bits (116), Expect = 6e-06
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 9/174 (5%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTK-------LDNVARECAQVGKKPLIIK 600
V +T A+ AK+GA++ I + + A E VG K L
Sbjct: 13 VFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCI 72
Query: 599 ADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVIL 420
D+ ++++ V++ I FG +D+L+NNA + L + D + N R L
Sbjct: 73 VDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTL-DTPTKRLDLMMNVNTRGTYL 131
Query: 419 ITSLAAPHLIETK-GNIINVS-SIGGTMVPMPGFLAYCMGKASLNHFTRGIALE 264
+ P+L ++K +I+N+S + V AY + K ++ + G+A E
Sbjct: 132 ASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEE 185
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 50.8 bits (116), Expect = 6e-06
Identities = 42/174 (24%), Positives = 75/174 (43%), Gaps = 9/174 (5%)
Frame = -3
Query: 758 VLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTK-------LDNVARECAQVGKKPLIIK 600
V +T A+ AK+GA++ I + + A E VG K L
Sbjct: 13 VFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAVGGKALPCI 72
Query: 599 ADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVIL 420
D+ ++++ V++ I FG +D+L+NNA + L + D + N R L
Sbjct: 73 VDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTL-DTPTKRLDLMMNVNTRGTYL 131
Query: 419 ITSLAAPHLIETK-GNIINVS-SIGGTMVPMPGFLAYCMGKASLNHFTRGIALE 264
+ P+L ++K +I+N+S + V AY + K ++ + G+A E
Sbjct: 132 ASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAEE 185
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 50.4 bits (115), Expect = 8e-06
Identities = 41/148 (27%), Positives = 70/148 (47%), Gaps = 6/148 (4%)
Frame = -3
Query: 779 MSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTK--LDNVARECAQVGKKPLI 606
M KV LVT A +GA VA+V N+ A + +K L
Sbjct: 1 MHVNGKVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQKTLF 60
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
I+ D+++ ++ + ++ +D FG+LD+L+NNAG+N ++++ NL +V
Sbjct: 61 IQCDVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE---------KNWEKTLQINLVSV 111
Query: 425 ILITSLAAPHLIETKGN----IINVSSI 354
I T L ++ + G IIN+SS+
Sbjct: 112 ISGTYLGLDYMSKQNGGEGGIIINMSSL 139
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG N+ + + + ++ + N + +T P L ++G I+ V S G
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGD 223
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIEN 195
M P P AY KA++ + EL P GV+ +II PG T+ + N
Sbjct: 224 M-PYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRN 272
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG N+ + + + ++ + N + +T P L ++G I+ V S G
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGD 223
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIEN 195
M P P AY KA++ + EL P GV+ +II PG T+ + N
Sbjct: 224 M-PYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRN 272
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG N+ + + + ++ + N + +T P L ++G I+ V S G
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGD 223
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIEN 195
M P P AY KA++ + EL P GV+ +II PG T+ + N
Sbjct: 224 M-PYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRN 272
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG N+ + + + ++ + N + +T P L ++G I+ V S G
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGD 223
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIEN 195
M P P AY KA++ + EL P GV+ +II PG T+ + N
Sbjct: 224 M-PYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRN 272
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG N+ + + + ++ + N + +T P L ++G I+ V S G
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGD 223
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIEN 195
M P P AY KA++ + EL P GV+ +II PG T+ + N
Sbjct: 224 M-PYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRN 272
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 50.0 bits (114), Expect = 1e-05
Identities = 33/110 (30%), Positives = 53/110 (48%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG N+ + + + ++ + N + +T P L ++G I+ V S G
Sbjct: 164 LVNNAGHNEVVADAELSPVATFRSCMEVNFFGALELTKGLLPLLRSSRGRIVTVGSPAGD 223
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIEN 195
M P P AY KA++ + EL P GV+ +II PG T+ + N
Sbjct: 224 M-PYPCLGAYGTSKAAVALLMDTFSCELLPWGVKVSIIQPGCFKTESVRN 272
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 50.0 bits (114), Expect = 1e-05
Identities = 34/103 (33%), Positives = 53/103 (51%), Gaps = 2/103 (1%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTA--TNLRAVILITSLAAPHLIETKGNIINVSSIG 351
L+NNAG++ + LL D VT NL VI +T P + + +G ++NVSS+
Sbjct: 109 LVNNAGISLPTA--PNELLTKQDFVTILDVNLLGVIDVTLSLLPLVRKARGRVVNVSSVM 166
Query: 350 GTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
G + G YC+ K + F+ + EL+ GV+ +I PG
Sbjct: 167 GRVSLFGG--GYCISKYGVEAFSDSLRRELSYFGVKVAMIEPG 207
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/189 (25%), Positives = 87/189 (46%), Gaps = 12/189 (6%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAY 315
LE + V NL + L A + + +G IIN +S+ G AY
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV-AAFEGQVGQAAY 168
Query: 314 CMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG 135
K + T IA +LAP G+ P+LT + E N ++ + +LG
Sbjct: 169 SASKGGIVGMTLPIARDLAPIGLFGT-----PLLTSLPEKVCNFLASQV----PFPSRLG 219
Query: 134 EPSEIAELM 108
+P+E A L+
Sbjct: 220 DPAEYAHLV 228
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 49.6 bits (113), Expect = 1e-05
Identities = 48/189 (25%), Positives = 87/189 (46%), Gaps = 12/189 (6%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSIGGTMVPMPGFLAY 315
LE + V NL + L A + + +G IIN +S+ G AY
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV-AAFEGQVGQAAY 168
Query: 314 CMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLG 135
K + T IA +LAP G+ P+LT + E N ++ + +LG
Sbjct: 169 SASKGGIVGMTLPIARDLAPIGLFGT-----PLLTSLPEKVCNFLASQV----PFPSRLG 219
Query: 134 EPSEIAELM 108
+P+E A L+
Sbjct: 220 DPAEYAHLV 228
>AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase
homolog isoform-1 protein.
Length = 279
Score = 49.6 bits (113), Expect = 1e-05
Identities = 45/186 (24%), Positives = 82/186 (44%), Gaps = 2/186 (1%)
Frame = -3
Query: 782 VMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLII 603
+ T+K + +T A F K+G V + +T+ + A + A+ ++ +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGFHV--IAACLTESGSTALK-AETSERLRTV 80
Query: 602 KADISNDEEAKTIVQQTIDAFGKLDV--LINNAGMNKSGSLLAGNLLESYDAVTATNLRA 429
D+++ E K Q + G+ + LINNAG+ + LE Y NL
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVNLFG 140
Query: 428 VILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+I +T P + + +G +INVSS+GG + + G Y K ++ F + ++ G
Sbjct: 141 LISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG--GYTPSKYAVEGFNDSLRRDMKAFG 198
Query: 248 VRANII 231
V + I
Sbjct: 199 VHVSCI 204
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 48.8 bits (111), Expect = 2e-05
Identities = 40/129 (31%), Positives = 61/129 (47%), Gaps = 1/129 (0%)
Frame = -3
Query: 467 ESYDAVTATNLRAVILITSLAAPHLIETKG-NIINVSSIGGTMVPMPGFLAYCMGKASLN 291
E +D N++A L+T P + + G +++ VSSI P PGF Y + K +L
Sbjct: 8 EVWDKTLDINVKAPALMTKAVVPEMEKRGGGSVVIVSSIAA-FSPSPGFSPYNVSKTALL 66
Query: 290 HFTRGIALELAPRGVRANIISPGPVLTDIIENSDNQISWDIFRAATALKKLGEPSEIAEL 111
+A+ELAPR +R N + D+ R A+A LGEP + A +
Sbjct: 67 GLNNTLAIELAPRNIRVNC-----------------LHLDLSRLASA-GWLGEPEDCAGI 108
Query: 110 MLFLASDKA 84
+ FL S+ A
Sbjct: 109 VSFLCSEDA 117
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/101 (27%), Positives = 48/101 (47%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG+ + + V N I +T P L + +G +IN++S+ G
Sbjct: 108 LVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGR 167
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
+ G YC+ K L F+ + ++A G+R +I+ PG
Sbjct: 168 LAANGG--GYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPG 206
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/101 (27%), Positives = 48/101 (47%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG+ + + V N I +T P L + +G +IN++S+ G
Sbjct: 108 LVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGR 167
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
+ G YC+ K L F+ + ++A G+R +I+ PG
Sbjct: 168 LAANGG--GYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPG 206
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 48.4 bits (110), Expect = 3e-05
Identities = 28/101 (27%), Positives = 48/101 (47%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG+ + + V N I +T P L + +G +IN++S+ G
Sbjct: 108 LVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGR 167
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
+ G YC+ K L F+ + ++A G+R +I+ PG
Sbjct: 168 LAANGG--GYCVSKFGLEAFSDSLRRDVAHFGIRVSIVEPG 206
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIET-KGNIINV 363
G++DVL+ NAG+ G L A ++ +V N+ + + P + G ++
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGE-DAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVT 141
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIE 198
S+GG M +P YC K +L +A+ L P GV ++I GPV T +E
Sbjct: 142 GSVGGLM-GLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFME 195
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 48.0 bits (109), Expect = 4e-05
Identities = 28/101 (27%), Positives = 48/101 (47%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG+ + + V N I +T P L + +G +IN++S+ G
Sbjct: 108 LVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMGPIGVTLALLPLLQQARGRVINITSVLGR 167
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
+ G YC+ K L F+ + ++A G+R +I+ PG
Sbjct: 168 LAANGG--GYCVSKFGLEAFSDSLRRDVAHFGIRESIVEPG 206
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIET-KGNIINV 363
G++DVL+ NAG+ G L A ++ +V N+ + + P + G ++
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGE-DAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVT 141
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIE 198
S+GG M +P YC K +L +A+ L P GV ++I GPV T +E
Sbjct: 142 GSVGGLM-GLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFME 195
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIET-KGNIINV 363
G++DVL+ NAG+ G L A ++ +V N+ + + P + G ++
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGE-DAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVT 141
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIE 198
S+GG M +P YC K +L +A+ L P GV ++I GPV T +E
Sbjct: 142 GSVGGLM-GLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFME 195
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIET-KGNIINV 363
G++DVL+ NAG+ G L A ++ +V N+ + + P + G ++
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGE-DAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVT 141
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIE 198
S+GG M +P YC K +L +A+ L P GV ++I GPV T +E
Sbjct: 142 GSVGGLM-GLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFME 195
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIET-KGNIINV 363
G++DVL+ NAG+ G L A ++ +V N+ + + P + G ++
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGE-DAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVT 141
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIE 198
S+GG M +P YC K +L +A+ L P GV ++I GPV T +E
Sbjct: 142 GSVGGLM-GLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFME 195
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIET-KGNIINV 363
G++DVL+ NAG+ G L A ++ +V N+ + + P + G ++
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGE-DAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVT 141
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIE 198
S+GG M +P YC K +L +A+ L P GV ++I GPV T +E
Sbjct: 142 GSVGGLM-GLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFME 195
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 48.0 bits (109), Expect = 4e-05
Identities = 34/115 (29%), Positives = 55/115 (47%), Gaps = 1/115 (0%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIET-KGNIINV 363
G++DVL+ NAG+ G L A ++ +V N+ + + P + G ++
Sbjct: 83 GRVDVLVCNAGLGLLGPLEALGE-DAVASVLDVNVVGTVRMLQAFLPDMKRRGSGRVLVT 141
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIE 198
S+GG M +P YC K +L +A+ L P GV ++I GPV T +E
Sbjct: 142 GSVGGLM-GLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFME 195
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 47.2 bits (107), Expect = 7e-05
Identities = 32/101 (31%), Positives = 49/101 (48%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG+ +L E + NL VI +T P + +G I+NVSSI G
Sbjct: 109 LVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGR 168
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
+ G YC+ K + F+ + E+ GV+ +I+ PG
Sbjct: 169 VAFFVG--GYCVSKYGVEAFSDILRREIQHFGVKISIVEPG 207
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 47.2 bits (107), Expect = 7e-05
Identities = 32/101 (31%), Positives = 49/101 (48%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG+ +L E + NL VI +T P + +G I+NVSSI G
Sbjct: 109 LVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGR 168
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
+ G YC+ K + F+ + E+ GV+ +I+ PG
Sbjct: 169 VAFFVG--GYCVSKYGVEAFSDILRREIQHFGVKISIVEPG 207
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 47.2 bits (107), Expect = 7e-05
Identities = 32/101 (31%), Positives = 49/101 (48%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGT 345
L+NNAG+ +L E + NL VI +T P + +G I+NVSSI G
Sbjct: 109 LVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQVTLSMLPLVRRARGRIVNVSSILGR 168
Query: 344 MVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
+ G YC+ K + F+ + E+ GV+ +I+ PG
Sbjct: 169 VAFFVG--GYCVSKYGVEAFSDILRREIQHFGVKISIVEPG 207
>CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein.
Length = 157
Score = 46.8 bits (106), Expect = 9e-05
Identities = 34/118 (28%), Positives = 58/118 (49%), Gaps = 3/118 (2%)
Frame = -3
Query: 389 ETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLT 210
E G+I+N+ I T P + +A + + T+ +ALE A G+R N ++PG + +
Sbjct: 3 EHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYS 60
Query: 209 D-IIEN--SDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+EN S Q ++ K++G P E++ ++ FL A ITG + D G
Sbjct: 61 QTAVENYGSWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLPPAASFITGQSVDVDGG 118
>BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein.
Length = 305
Score = 46.0 bits (104), Expect = 2e-04
Identities = 59/233 (25%), Positives = 98/233 (42%), Gaps = 15/233 (6%)
Frame = -3
Query: 704 AKEGADVAIVGRNVTKLDNVARECAQV--GKKPLIIKADISNDEEAKTIVQQTIDAFGKL 531
A GA V + R+V K + VA+E ++ L+ K D+S+ + + + + L
Sbjct: 49 ANTGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDLSDTKSIRAFAKGFLAEEKHL 108
Query: 530 DVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIET-KGNIINVSSI 354
VLINNAG+ + ++ N L+T L L E+ I+NV S+
Sbjct: 109 HVLINNAGVMMCP---YSKTADGFEMHIGVNHLGHFLLTHLLLEKLKESAPSRIVNVFSL 165
Query: 353 G------------GTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLT 210
G G LAYC K + FT+ +A L GV + PG V +
Sbjct: 166 AHHLGRIHFHNLQGEKFYNAG-LAYCHSKLANILFTQELARRLKGSGVTTYSVHPGTVQS 224
Query: 209 DIIENSDNQISWDIFRAATALKKLGEPSEIAELMLFLASDKARSITGSNYVSD 51
+++ +S + + W + + +K P + A+ L A + I N+ SD
Sbjct: 225 ELVRHS-SFMRWMWWLFSFFIK---TPQQGAQTSLHCALTEGLEILSGNHFSD 273
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 46.0 bits (104), Expect = 2e-04
Identities = 32/103 (31%), Positives = 51/103 (49%), Gaps = 2/103 (1%)
Frame = -3
Query: 524 LINNAGMNKSGSLLAGNLLESYDAVTA--TNLRAVILITSLAAPHLIETKGNIINVSSIG 351
L+NNAG++ + LL D +T NL VI +T P + +G ++NV S+
Sbjct: 109 LVNNAGISLPTA--PNELLTKQDLLTILDVNLLGVIDVTLNLLPLVRRARGRVVNVFSVM 166
Query: 350 GTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPG 222
G + G YC+ K + F+ + EL+ GV+ +I PG
Sbjct: 167 GRVSLFGG--GYCISKYGVEAFSDSLRRELSYFGVKVAMIEPG 207
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 1/142 (0%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISN 585
KV+++T A+ FA+EGA V N +KL + + G + ++
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK---YPGIQTRVL------ 57
Query: 584 DEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLA 405
D K + Q + +LDVL N AG G++L + +D N+R++ L+
Sbjct: 58 DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCE-EKDWDFSMNLNVRSMYLMIKAF 116
Query: 404 APHLIETK-GNIINVSSIGGTM 342
P ++ K GNIIN+SS+ ++
Sbjct: 117 LPKMLAQKSGNIINMSSVASSV 138
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 45.6 bits (103), Expect = 2e-04
Identities = 39/142 (27%), Positives = 67/142 (47%), Gaps = 1/142 (0%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISN 585
KV+++T A+ FA+EGA V N +KL + + G + ++
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK---YPGIQTRVL------ 57
Query: 584 DEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLA 405
D K + Q + +LDVL N AG G++L + +D N+R++ L+
Sbjct: 58 DVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCE-EKDWDFSMNLNVRSMYLMIKAF 116
Query: 404 APHLIETK-GNIINVSSIGGTM 342
P ++ K GNIIN+SS+ ++
Sbjct: 117 LPKMLAQKSGNIINMSSVASSV 138
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 45.2 bits (102), Expect = 3e-04
Identities = 39/142 (27%), Positives = 66/142 (46%), Gaps = 1/142 (0%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADISN 585
KV+++T A+ FA+EGA V N +KL + + G + ++
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEK---YPGIQTRVL------ 57
Query: 584 DEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLA 405
D K + Q +LDVL N AG G++L + +D N+R++ L+
Sbjct: 58 DVTKKKQIDQFASEVERLDVLFNVAGFVHHGTVLDCE-EKDWDFSMNLNVRSMYLMIKAF 116
Query: 404 APHLIETK-GNIINVSSIGGTM 342
P ++ K GNIIN+SS+ ++
Sbjct: 117 LPKMLAQKSGNIINMSSVASSV 138
>AY268353-1|AAP42287.1| 199|Homo sapiens short-chain
dehydrogenase/reductase 10c protein.
Length = 199
Score = 44.8 bits (101), Expect = 4e-04
Identities = 36/123 (29%), Positives = 59/123 (47%), Gaps = 3/123 (2%)
Frame = -3
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDA---VTATNLRAVI 423
+++ E +++VQ +D G LD L+ +N G AG S A + N + +
Sbjct: 1 MASPEAPESVVQFALDKLGGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYV 56
Query: 422 LITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVR 243
+TS A P L ++KG+++ VSS+ G VP Y K +L+ F + EL + V
Sbjct: 57 QLTSRALPSLTDSKGSLVVVSSLLG-RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVN 115
Query: 242 ANI 234
I
Sbjct: 116 VAI 118
>AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid
dehydrogenase isoform 1 protein.
Length = 264
Score = 44.4 bits (100), Expect = 5e-04
Identities = 37/153 (24%), Positives = 67/153 (43%), Gaps = 4/153 (2%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETK-GNIINV 363
G + +++NNAG LL+ E N+ IT P ++E G+I+ V
Sbjct: 76 GDVTIVVNNAGTVYPADLLSTKD-EEITKTFEVNILGHFWITKALLPSMMERNHGHIVTV 134
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALE---LAPRGVRANIISPGPVLTDIIENS 192
+S+ G +P + YC K + F RG+ E L G++ + + P V T +N
Sbjct: 135 ASVCGHE-GIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGIKTSCLCPVFVNTGFTKNP 193
Query: 191 DNQISWDIFRAATALKKLGEPSEIAELMLFLAS 93
++ W + ++ L + + M+F+ S
Sbjct: 194 STRL-WPVLETDEVVRSLIDGILTNKKMIFVPS 225
>M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase protein.
Length = 214
Score = 43.2 bits (97), Expect = 0.001
Identities = 34/137 (24%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Frame = -3
Query: 605 IKADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAV 426
++ D+ N ++ + G++DVL+ N G+ G L G ++ +V N+
Sbjct: 63 LQLDVRNSSSLAAARERVTE--GRVDVLVCNTGLGLLGPL--GE--DAVASVLDVNVVGT 116
Query: 425 ILITSLAAPHLIET-KGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG 249
+ + P + G ++ S+GG M +P YC K +L +A+ L P G
Sbjct: 117 VRVLQDFLPDMKRPGSGRVLVTGSMGGLM-GLPFNDVYCASKFALEGLCESLAVLLLPFG 175
Query: 248 VRANIISPGPVLTDIIE 198
V ++I GPV T ++
Sbjct: 176 VHVSLIECGPVDTAFMQ 192
>M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase
protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/138 (28%), Positives = 68/138 (49%), Gaps = 6/138 (4%)
Frame = -3
Query: 527 VLINNAGMNKSGSLLAGNLLESYDAVT--ATNLRAVILITSLAAPHLIETKG---NIINV 363
+LINNAG S +L +S A NL +++ +TS ++ G ++N+
Sbjct: 96 LLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNI 155
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENS-DN 186
SS+ + P G+ YC GKA+ + + +ALE VR +PGP+ TD+ + + +
Sbjct: 156 SSLCA-LQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARET 212
Query: 185 QISWDIFRAATALKKLGE 132
+ D+ + LK G+
Sbjct: 213 SVDPDMRKGLQELKAKGK 230
>BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/138 (28%), Positives = 68/138 (49%), Gaps = 6/138 (4%)
Frame = -3
Query: 527 VLINNAGMNKSGSLLAGNLLESYDAVT--ATNLRAVILITSLAAPHLIETKG---NIINV 363
+LINNAG S +L +S A NL +++ +TS ++ G ++N+
Sbjct: 96 LLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNI 155
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENS-DN 186
SS+ + P G+ YC GKA+ + + +ALE VR +PGP+ TD+ + + +
Sbjct: 156 SSLCA-LQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARET 212
Query: 185 QISWDIFRAATALKKLGE 132
+ D+ + LK G+
Sbjct: 213 SVDPDMRKGLQELKAKGK 230
>AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) variant
protein.
Length = 261
Score = 42.7 bits (96), Expect = 0.002
Identities = 39/138 (28%), Positives = 68/138 (49%), Gaps = 6/138 (4%)
Frame = -3
Query: 527 VLINNAGMNKSGSLLAGNLLESYDAVT--ATNLRAVILITSLAAPHLIETKG---NIINV 363
+LINNAG S +L +S A NL +++ +TS ++ G ++N+
Sbjct: 96 LLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNI 155
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANIISPGPVLTDIIENS-DN 186
SS+ + P G+ YC GKA+ + + +ALE VR +PGP+ TD+ + + +
Sbjct: 156 SSLCA-LQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARET 212
Query: 185 QISWDIFRAATALKKLGE 132
+ D+ + LK G+
Sbjct: 213 SVDPDMRKGLQELKAKGK 230
>CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 41.5 bits (93), Expect = 0.004
Identities = 53/213 (24%), Positives = 86/213 (40%), Gaps = 22/213 (10%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQ--VGKKPLIIKAD 594
++V +VT A H A+ G V I G N +K V + + + K + D
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAG------------------MNKSGSLLAGNLL 468
+++ + VQ+ L VLINNAG +N G L NLL
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLL 162
Query: 467 ESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNH 288
+ + + ++T +A H + +N+ + + P AY K +L
Sbjct: 163 LDTLKESGSPGHSARVVTVSSATHYVAE----LNMDDLQSSACYSP-HAAYAQSKLALVL 217
Query: 287 FTRGIALELAPRG--VRANIISPGPVLTDIIEN 195
FT + LA G V AN++ PG V TD+ ++
Sbjct: 218 FTYHLQRLLAAEGSHVTANVVDPGVVNTDVYKH 250
>BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 41.5 bits (93), Expect = 0.004
Identities = 53/213 (24%), Positives = 86/213 (40%), Gaps = 22/213 (10%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQ--VGKKPLIIKAD 594
++V +VT A H A+ G V I G N +K V + + + K + D
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAG------------------MNKSGSLLAGNLL 468
+++ + VQ+ L VLINNAG +N G L NLL
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLL 162
Query: 467 ESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNH 288
+ + + ++T +A H + +N+ + + P AY K +L
Sbjct: 163 LDTLKESGSPGHSARVVTVSSATHYVAE----LNMDDLQSSACYSP-HAAYAQSKLALVL 217
Query: 287 FTRGIALELAPRG--VRANIISPGPVLTDIIEN 195
FT + LA G V AN++ PG V TD+ ++
Sbjct: 218 FTYHLQRLLAAEGSHVTANVVDPGVVNTDVYKH 250
>BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein.
Length = 330
Score = 41.5 bits (93), Expect = 0.004
Identities = 53/213 (24%), Positives = 86/213 (40%), Gaps = 22/213 (10%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQ--VGKKPLIIKAD 594
++V +VT A H A+ G V I G N +K V + + + K + D
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAG------------------MNKSGSLLAGNLL 468
+++ + VQ+ L VLINNAG +N G L NLL
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLL 162
Query: 467 ESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNH 288
+ + + ++T +A H + +N+ + + P AY K +L
Sbjct: 163 LDTLKESGSPGHSARVVTVSSATHYVAE----LNMDDLQSSACYSP-HAAYAQSKLALVL 217
Query: 287 FTRGIALELAPRG--VRANIISPGPVLTDIIEN 195
FT + LA G V AN++ PG V TD+ ++
Sbjct: 218 FTYHLQRLLAAEGSHVTANVVDPGVVNTDVYKH 250
>AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein.
Length = 330
Score = 41.5 bits (93), Expect = 0.004
Identities = 53/213 (24%), Positives = 86/213 (40%), Gaps = 22/213 (10%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQ--VGKKPLIIKAD 594
++V +VT A H A+ G V I G N +K V + + + K + D
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNAG------------------MNKSGSLLAGNLL 468
+++ + VQ+ L VLINNAG +N G L NLL
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLL 162
Query: 467 ESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNH 288
+ + + ++T +A H + +N+ + + P AY K +L
Sbjct: 163 LDTLKESGSPGHSARVVTVSSATHYVAE----LNMDDLQSSACYSP-HAAYAQSKLALVL 217
Query: 287 FTRGIALELAPRG--VRANIISPGPVLTDIIEN 195
FT + LA G V AN++ PG V TD+ ++
Sbjct: 218 FTYHLQRLLAAEGSHVTANVVDPGVVNTDVYKH 250
>AL645761-2|CAI15000.1| 147|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 147
Score = 41.5 bits (93), Expect = 0.004
Identities = 36/138 (26%), Positives = 62/138 (44%), Gaps = 5/138 (3%)
Frame = -3
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGN---LLESYDAVTATNLRAV 426
D+ N EE + + G + +L+NNA + SL+ + LL+S N
Sbjct: 11 DVGNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHI----NTLGQ 66
Query: 425 ILITSLAAPHLIETK-GNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAP-R 252
T P ++E + G+I+ ++S+ + +PG + YC KAS F + L L
Sbjct: 67 FWTTKAFLPRMLELQNGHIVCLNSVLA-LSAIPGAIDYCTSKASAFAFMESLTLGLLDCP 125
Query: 251 GVRANIISPGPVLTDIIE 198
GV A + P T++ +
Sbjct: 126 GVSATTVLPFHTSTEMFQ 143
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 41.5 bits (93), Expect = 0.004
Identities = 44/197 (22%), Positives = 80/197 (40%), Gaps = 8/197 (4%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADIS 588
++VL+T A+ FA+ G+ + + N + + + G + D S
Sbjct: 41 EIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVRAYTCDCS 100
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLL--AGNLLE-SYDAVTATNLRAVILI 417
E + Q G + +LINNAG+ L L+E S+D N +A +
Sbjct: 101 QKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFD----VNFKAHLWT 156
Query: 416 TSLAAPHLI-ETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALEL---APRG 249
P +I G+++ +SS G + + G YC K + F + +E +G
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAG-LSGVNGLADYCASKFAAFGFAESVFVETFVQKQKG 215
Query: 248 VRANIISPGPVLTDIIE 198
++ I+ P + T + E
Sbjct: 216 IKTTIVCPFFIKTGMFE 232
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 41.1 bits (92), Expect = 0.005
Identities = 44/197 (22%), Positives = 80/197 (40%), Gaps = 8/197 (4%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADIS 588
++VL+T A+ FA+ G+ + + N + + + G + D S
Sbjct: 41 EIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCS 100
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLL--AGNLLE-SYDAVTATNLRAVILI 417
E + Q G + +LINNAG+ L L+E S+D N +A +
Sbjct: 101 QKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFD----VNFKAHLWT 156
Query: 416 TSLAAPHLI-ETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALEL---APRG 249
P +I G+++ +SS G + + G YC K + F + +E +G
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAG-LSGVNGLADYCASKFAAFGFAESVFVETFVQKQKG 215
Query: 248 VRANIISPGPVLTDIIE 198
++ I+ P + T + E
Sbjct: 216 IKTTIVCPFFIKTGMFE 232
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 41.1 bits (92), Expect = 0.005
Identities = 44/197 (22%), Positives = 80/197 (40%), Gaps = 8/197 (4%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADIS 588
++VL+T A+ FA+ G+ + + N + + + G + D S
Sbjct: 41 EIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCS 100
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLL--AGNLLE-SYDAVTATNLRAVILI 417
E + Q G + +LINNAG+ L L+E S+D N +A +
Sbjct: 101 QKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFD----VNFKAHLWT 156
Query: 416 TSLAAPHLI-ETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALEL---APRG 249
P +I G+++ +SS G + + G YC K + F + +E +G
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAG-LSGVNGLADYCASKFAAFGFAESVFVETFVQKQKG 215
Query: 248 VRANIISPGPVLTDIIE 198
++ I+ P + T + E
Sbjct: 216 IKTTIVCPFFIKTGMFE 232
>BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 330
Score = 41.1 bits (92), Expect = 0.005
Identities = 53/213 (24%), Positives = 86/213 (40%), Gaps = 22/213 (10%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQ--VGKKPLIIKAD 594
++V +VT A H A+ G V I G N +K V + + + K + D
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNA------------------GMNKSGSLLAGNLL 468
+++ + VQ+ L VLINNA G+N G L NLL
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLL 162
Query: 467 ESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNH 288
+ + + ++T +A H + +N+ + + P AY K +L
Sbjct: 163 LDTLKESGSPGHSARVVTVSSATHYVAE----LNMDDLQSSACYSP-HAAYAQSKLALVL 217
Query: 287 FTRGIALELAPRG--VRANIISPGPVLTDIIEN 195
FT + LA G V AN++ PG V TD+ ++
Sbjct: 218 FTYHLQRLLAAEGSHVTANVVDPGVVNTDLYKH 250
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 41.1 bits (92), Expect = 0.005
Identities = 42/202 (20%), Positives = 82/202 (40%), Gaps = 15/202 (7%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA--QVGKKPLIIKADI 591
K V+VT A+ A+ G ++ + R++ K + A++ + D+
Sbjct: 39 KTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDL 98
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
++ + + + I+ ++D+LINNAG+ + + ++ N L+T+
Sbjct: 99 ASLKSIRVFAAKIIEEEERVDILINNAGVMRCPHWTTE---DGFEMQFGVNHLGHFLLTN 155
Query: 410 LAAPHL-IETKGNIINVSSIGGTM--VPMPGF----------LAYCMGKASLNHFTRGIA 270
L L IIN+SS+ + AYC K ++ FT+ ++
Sbjct: 156 LLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELS 215
Query: 269 LELAPRGVRANIISPGPVLTDI 204
L GV N + PG T++
Sbjct: 216 RRLQGSGVTVNALHPGVARTEL 237
>AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase
protein.
Length = 330
Score = 41.1 bits (92), Expect = 0.005
Identities = 53/213 (24%), Positives = 86/213 (40%), Gaps = 22/213 (10%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQ--VGKKPLIIKAD 594
++V +VT A H A+ G V I G N +K V + + + K + D
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 593 ISNDEEAKTIVQQTIDAFGKLDVLINNA------------------GMNKSGSLLAGNLL 468
+++ + VQ+ L VLINNA G+N G L NLL
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRDGFEEHFGLNYLGHFLLTNLL 162
Query: 467 ESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNH 288
+ + + ++T +A H + +N+ + + P AY K +L
Sbjct: 163 LDTLKESGSPGHSARVVTVSSATHYVAE----LNMDDLQSSACYSP-HAAYAQSKLALVL 217
Query: 287 FTRGIALELAPRG--VRANIISPGPVLTDIIEN 195
FT + LA G V AN++ PG V TD+ ++
Sbjct: 218 FTYHLQRLLAAEGSHVTANVVDPGVVNTDLYKH 250
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 40.7 bits (91), Expect = 0.006
Identities = 42/202 (20%), Positives = 82/202 (40%), Gaps = 15/202 (7%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA--QVGKKPLIIKADI 591
K V+VT A+ A+ G ++ + R++ K + A++ + D+
Sbjct: 39 KTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNHHVNARHLDL 98
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
++ + + + I+ ++D+LINNAG+ + + ++ N L+T+
Sbjct: 99 ASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTE---DGFEMQFGVNHLGHFLLTN 155
Query: 410 LAAPHL-IETKGNIINVSSIGGTM--VPMPGF----------LAYCMGKASLNHFTRGIA 270
L L IIN+SS+ + AYC K ++ FT+ ++
Sbjct: 156 LLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELS 215
Query: 269 LELAPRGVRANIISPGPVLTDI 204
L GV N + PG T++
Sbjct: 216 RRLQGSGVTVNALHPGVARTEL 237
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 40.3 bits (90), Expect = 0.008
Identities = 25/80 (31%), Positives = 43/80 (53%), Gaps = 1/80 (1%)
Frame = -3
Query: 440 NLRAVILITSLAAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALE 264
N+ +V +T L P ++E +KG I+N+SS G M+P+P Y K ++ F++ + E
Sbjct: 26 NILSVCKMTQLVLPGMVERSKGAILNISS-GSGMLPVPLLTIYSATKTFVDFFSQCLHEE 84
Query: 263 LAPRGVRANIISPGPVLTDI 204
+GV + P V T +
Sbjct: 85 YRSKGVFVQSVLPYFVATKL 104
>M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase
(NAPDH)1, EC 1.1.1.184 protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 39.5 bits (88), Expect = 0.014
Identities = 42/188 (22%), Positives = 76/188 (40%), Gaps = 8/188 (4%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPL-IIKADIS 588
++VL+T A+ FA+ G+ + + N + + + G + D S
Sbjct: 41 EIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVHAYTCDCS 100
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLL--AGNLLE-SYDAVTATNLRAVILI 417
E + Q G + +LINNAG+ L L+E S+D N +A +
Sbjct: 101 QKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFD----VNFKAHLWT 156
Query: 416 TSLAAPHLI-ETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALEL---APRG 249
P +I G+++ +SS G + + G YC K + F + +E +G
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAG-LSGVNGLADYCASKFAAFGFAESVFVETFVQKQKG 215
Query: 248 VRANIISP 225
++ I+ P
Sbjct: 216 IKTTIVCP 223
>AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase
protein.
Length = 277
Score = 39.5 bits (88), Expect = 0.014
Identities = 29/112 (25%), Positives = 53/112 (47%)
Frame = -3
Query: 689 DVAIVGRNVTKLDNVARECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNA 510
DV + R+VT+ ++ G P + DI + + + + +G LDVL+NNA
Sbjct: 32 DVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDDLQSIRALRDFLRKEYGGLDVLVNNA 91
Query: 509 GMNKSGSLLAGNLLESYDAVTATNLRAVILITSLAAPHLIETKGNIINVSSI 354
G+ + +++ + TN + + P LI+ +G ++NVSSI
Sbjct: 92 GIAFKVADPTPFHIQA-EVTMKTNFFGTRDVCTELLP-LIKPQGRVVNVSSI 141
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 38.7 bits (86), Expect = 0.025
Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 2/89 (2%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQV--GKKPLIIKADI 591
KVV+VT A A+ GA V + R+V K + VA+E ++ L+ K D+
Sbjct: 42 KVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQQVLVRKLDL 101
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGM 504
S+ + + + + L VLINNAG+
Sbjct: 102 SDTKSIRAFAKGFLAEEKHLHVLINNAGV 130
>AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retinol
dehydrogenase A2 isoform protein.
Length = 188
Score = 38.3 bits (85), Expect = 0.033
Identities = 22/89 (24%), Positives = 36/89 (40%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
NKV LVT A A++GA V + R +D G +
Sbjct: 32 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVG 91
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMN 501
E+ + +V + G +D+L++NA +N
Sbjct: 92 KAEDRERLVATAVKLHGGIDILVSNAAVN 120
>AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol
dehydrogenase short isoform protein.
Length = 174
Score = 38.3 bits (85), Expect = 0.033
Identities = 22/89 (24%), Positives = 36/89 (40%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
NKV LVT A A++GA V + R +D G +
Sbjct: 14 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCHVG 73
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMN 501
E+ + +V + G +D+L++NA +N
Sbjct: 74 KAEDRERLVATAVKLHGGIDILVSNAAVN 102
Score = 31.9 bits (69), Expect = 2.8
Identities = 14/35 (40%), Positives = 21/35 (60%)
Frame = -3
Query: 149 LKKLGEPSEIAELMLFLASDKARSITGSNYVSDNG 45
+++LGEP + A ++ FL S+ A ITG V G
Sbjct: 135 IRRLGEPEDCAGIVSFLCSEDASYITGETVVVGGG 169
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 37.5 bits (83), Expect = 0.057
Identities = 25/106 (23%), Positives = 44/106 (41%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQVGKKPLIIKADIS 588
N+V +VT A A++GA V I R +D + G I +
Sbjct: 53 NRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAGIVCHVG 112
Query: 587 NDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAV 450
E+ + +V + ++ G +D L+ +AG+N G + +D V
Sbjct: 113 KAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKV 158
>BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein.
Length = 312
Score = 36.7 bits (81), Expect = 0.100
Identities = 45/154 (29%), Positives = 66/154 (42%), Gaps = 2/154 (1%)
Frame = -3
Query: 794 HGVDVMSFTNKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECA-QVGK 618
H ++V +V LVT A+ AK G V +V R+ ++ E + G
Sbjct: 27 HDLEVQ-IPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQAPAEDARGEIIRESGN 85
Query: 617 KPLIIK-ADISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTAT 441
+ + + D+S+ ++ V+ KL VLINNAG + L + LE A A
Sbjct: 86 QNIFLHIVDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKRELTEDGLEKNFA--AN 142
Query: 440 NLRAVILITSLAAPHLIETKGNIINVSSIGGTMV 339
L IL T L E +I VSS GG +V
Sbjct: 143 TLGVYILTTGLIPVLEKEHDPRVITVSS-GGMLV 175
>BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 14
(all-trans/9-cis/11-cis) protein.
Length = 336
Score = 36.7 bits (81), Expect = 0.100
Identities = 63/272 (23%), Positives = 105/272 (38%), Gaps = 34/272 (12%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVA-------RECAQVGKKP-- 612
K VL+T A + GA V + R+ + + A R+ A+ G +P
Sbjct: 44 KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGV 103
Query: 611 -----LIIKA-DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAV 450
LI++ D+++ + Q+ + +LDVLINNAG+ + + + E V
Sbjct: 104 SGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGV 163
Query: 449 T------ATNLRAVILITSLAAPHLIET----KGNIINVSSIGGTMVPMPGFLAYCMGKA 300
TNL +L +S + ++ + K IN + F Y K
Sbjct: 164 NHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSF-CYSRSKL 222
Query: 299 SLNHFTRGIALELAPRGVRANIISPGPVLTD---------IIENSDNQISWDIFRAATAL 147
+ FTR +A L V N++ PG V T+ +++ N +SW F+
Sbjct: 223 ANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKT---- 278
Query: 146 KKLGEPSEIAELMLFLASDKARSITGSNYVSD 51
P E A+ ++LAS Y D
Sbjct: 279 -----PVEGAQTSIYLASSPEVEGVSGRYFGD 305
>AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 36.7 bits (81), Expect = 0.100
Identities = 63/272 (23%), Positives = 105/272 (38%), Gaps = 34/272 (12%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVA-------RECAQVGKKP-- 612
K VL+T A + GA V + R+ + + A R+ A+ G +P
Sbjct: 44 KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGV 103
Query: 611 -----LIIKA-DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAV 450
LI++ D+++ + Q+ + +LDVLINNAG+ + + + E V
Sbjct: 104 SGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGV 163
Query: 449 T------ATNLRAVILITSLAAPHLIET----KGNIINVSSIGGTMVPMPGFLAYCMGKA 300
TNL +L +S + ++ + K IN + F Y K
Sbjct: 164 NHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSF-CYSRSKL 222
Query: 299 SLNHFTRGIALELAPRGVRANIISPGPVLTD---------IIENSDNQISWDIFRAATAL 147
+ FTR +A L V N++ PG V T+ +++ N +SW F+
Sbjct: 223 ANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKT---- 278
Query: 146 KKLGEPSEIAELMLFLASDKARSITGSNYVSD 51
P E A+ ++LAS Y D
Sbjct: 279 -----PVEGAQTSIYLASSPEVEGVSGRYFGD 305
>AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 36.7 bits (81), Expect = 0.100
Identities = 63/272 (23%), Positives = 105/272 (38%), Gaps = 34/272 (12%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVA-------RECAQVGKKP-- 612
K VL+T A + GA V + R+ + + A R+ A+ G +P
Sbjct: 44 KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGV 103
Query: 611 -----LIIKA-DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAV 450
LI++ D+++ + Q+ + +LDVLINNAG+ + + + E V
Sbjct: 104 SGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGV 163
Query: 449 T------ATNLRAVILITSLAAPHLIET----KGNIINVSSIGGTMVPMPGFLAYCMGKA 300
TNL +L +S + ++ + K IN + F Y K
Sbjct: 164 NHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSF-CYSRSKL 222
Query: 299 SLNHFTRGIALELAPRGVRANIISPGPVLTD---------IIENSDNQISWDIFRAATAL 147
+ FTR +A L V N++ PG V T+ +++ N +SW F+
Sbjct: 223 ANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKT---- 278
Query: 146 KKLGEPSEIAELMLFLASDKARSITGSNYVSD 51
P E A+ ++LAS Y D
Sbjct: 279 -----PVEGAQTSIYLASSPEVEGVSGRYFGD 305
>AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 36.7 bits (81), Expect = 0.100
Identities = 63/272 (23%), Positives = 105/272 (38%), Gaps = 34/272 (12%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVA-------RECAQVGKKP-- 612
K VL+T A + GA V + R+ + + A R+ A+ G +P
Sbjct: 44 KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGV 103
Query: 611 -----LIIKA-DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAV 450
LI++ D+++ + Q+ + +LDVLINNAG+ + + + E V
Sbjct: 104 SGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTEDGFEMQFGV 163
Query: 449 T------ATNLRAVILITSLAAPHLIET----KGNIINVSSIGGTMVPMPGFLAYCMGKA 300
TNL +L +S + ++ + K IN + F Y K
Sbjct: 164 NHLGHFLLTNLLLGLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSF-CYSRSKL 222
Query: 299 SLNHFTRGIALELAPRGVRANIISPGPVLTD---------IIENSDNQISWDIFRAATAL 147
+ FTR +A L V N++ PG V T+ +++ N +SW F+
Sbjct: 223 ANILFTRELARRLEGTNVTVNVLHPGIVRTNLGRHIHIPLLVKPLFNLVSWAFFKT---- 278
Query: 146 KKLGEPSEIAELMLFLASDKARSITGSNYVSD 51
P E A+ ++LAS Y D
Sbjct: 279 -----PVEGAQTSIYLASSPEVEGVSGRYFGD 305
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 35.9 bits (79), Expect = 0.17
Identities = 32/128 (25%), Positives = 53/128 (41%), Gaps = 4/128 (3%)
Frame = -3
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D+ E ++ G++ VL+NNAG+ SG L E + N A
Sbjct: 118 DVGKRENVYLTAERVRKEVGEVSVLVNNAGV-VSGHHLLECPDELIERTMMVNCHAHFWT 176
Query: 416 TSLAAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR---G 249
T P ++E G+I+ V+S G + G YC K + F ++ EL G
Sbjct: 177 TKAFLPTMLEINHGHIVTVASSLG-LFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 248 VRANIISP 225
++ ++ P
Sbjct: 236 IKTTLVCP 243
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 35.9 bits (79), Expect = 0.17
Identities = 32/128 (25%), Positives = 53/128 (41%), Gaps = 4/128 (3%)
Frame = -3
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D+ E ++ G++ VL+NNAG+ SG L E + N A
Sbjct: 118 DVGKRENVYLTAERVRKEVGEVSVLVNNAGV-VSGHHLLECPDELIERTMMVNCHAHFWT 176
Query: 416 TSLAAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR---G 249
T P ++E G+I+ V+S G + G YC K + F ++ EL G
Sbjct: 177 TKAFLPTMLEINHGHIVTVASSLG-LFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 248 VRANIISP 225
++ ++ P
Sbjct: 236 IKTTLVCP 243
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 35.9 bits (79), Expect = 0.17
Identities = 32/128 (25%), Positives = 53/128 (41%), Gaps = 4/128 (3%)
Frame = -3
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
D+ E ++ G++ VL+NNAG+ SG L E + N A
Sbjct: 118 DVGKRENVYLTAERVRKEVGEVSVLVNNAGV-VSGHHLLECPDELIERTMMVNCHAHFWT 176
Query: 416 TSLAAPHLIE-TKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPR---G 249
T P ++E G+I+ V+S G + G YC K + F ++ EL G
Sbjct: 177 TKAFLPTMLEINHGHIVTVASSLG-LFSTAGVEDYCASKFGVVGFHESLSHELKAAEKDG 235
Query: 248 VRANIISP 225
++ ++ P
Sbjct: 236 IKTTLVCP 243
>CR381696-1|CAI95409.1| 245|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 245
Score = 35.5 bits (78), Expect = 0.23
Identities = 49/196 (25%), Positives = 82/196 (41%), Gaps = 5/196 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVA--RECAQVGK-KPLIIKA 597
++V +VT A H A+ G V IV L ++ R+ Q K K + +
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIVEFLYCDLASMTSIRQFVQKFKMKKIPLHV 102
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
I+N ++T D F + + G+N G L NLL + + + ++
Sbjct: 103 LINNAGVMMVPQRKTRDGFEE------HFGLNYLGHFLLTNLLLDTLKESGSPGHSARVV 156
Query: 416 TSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG--VR 243
T +A H + +N+ + + P AY K +L FT + LA G V
Sbjct: 157 TVSSATHYVAE----LNMDDLQSSACYSP-HAAYAQSKLALVLFTYHLQRLLAAEGSHVT 211
Query: 242 ANIISPGPVLTDIIEN 195
AN++ PG V TD+ ++
Sbjct: 212 ANVVDPGVVNTDVYKH 227
>BX649443-1|CAI95430.1| 245|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 245
Score = 35.5 bits (78), Expect = 0.23
Identities = 49/196 (25%), Positives = 82/196 (41%), Gaps = 5/196 (2%)
Frame = -3
Query: 767 NKVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVA--RECAQVGK-KPLIIKA 597
++V +VT A H A+ G V IV L ++ R+ Q K K + +
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIVEFLYCDLASMTSIRQFVQKFKMKKIPLHV 102
Query: 596 DISNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILI 417
I+N ++T D F + + G+N G L NLL + + + ++
Sbjct: 103 LINNAGVMMVPQRKTRDGFEE------HFGLNYLGHFLLTNLLLDTLKESGSPGHSARVV 156
Query: 416 TSLAAPHLIETKGNIINVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRG--VR 243
T +A H + +N+ + + P AY K +L FT + LA G V
Sbjct: 157 TVSSATHYVAE----LNMDDLQSSACYSP-HAAYAQSKLALVLFTYHLQRLLAAEGSHVT 211
Query: 242 ANIISPGPVLTDIIEN 195
AN++ PG V TD+ ++
Sbjct: 212 ANVVDPGVVNTDVYKH 227
>BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein.
Length = 181
Score = 35.5 bits (78), Expect = 0.23
Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 3/105 (2%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDA---VTATNLRAVILITSLAAPHLIETKGNII 369
G LD L+ +N G AG S A + N + + +TS A P L ++KG+++
Sbjct: 1 GGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLV 56
Query: 368 NVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANI 234
VSS+ G VP Y K +L+ F + EL + V I
Sbjct: 57 VVSSLLG-RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 100
>BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein.
Length = 181
Score = 35.5 bits (78), Expect = 0.23
Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 3/105 (2%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDA---VTATNLRAVILITSLAAPHLIETKGNII 369
G LD L+ +N G AG S A + N + + +TS A P L ++KG+++
Sbjct: 1 GGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLV 56
Query: 368 NVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANI 234
VSS+ G VP Y K +L+ F + EL + V I
Sbjct: 57 VVSSLLG-RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 100
>AY313896-1|AAP83168.1| 234|Homo sapiens short-chain
dehydrogenase/reductase 10g protein.
Length = 234
Score = 35.5 bits (78), Expect = 0.23
Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 3/105 (2%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDA---VTATNLRAVILITSLAAPHLIETKGNII 369
G LD L+ +N G AG S A + N + + +TS A P L ++KG+++
Sbjct: 25 GGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLV 80
Query: 368 NVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANI 234
VSS+ G VP Y K +L+ F + EL + V I
Sbjct: 81 VVSSLLG-RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 124
>AY268351-1|AAP42285.1| 205|Homo sapiens short-chain
dehydrogenase/reductase 10a protein.
Length = 205
Score = 35.5 bits (78), Expect = 0.23
Identities = 32/105 (30%), Positives = 48/105 (45%), Gaps = 3/105 (2%)
Frame = -3
Query: 539 GKLDVLINNAGMNKSGSLLAGNLLESYDA---VTATNLRAVILITSLAAPHLIETKGNII 369
G LD L+ +N G AG S A + N + + +TS A P L ++KG+++
Sbjct: 25 GGLDYLV----LNHIGGAPAGTRARSPQATRWLMQVNFVSYVQLTSRALPSLTDSKGSLV 80
Query: 368 NVSSIGGTMVPMPGFLAYCMGKASLNHFTRGIALELAPRGVRANI 234
VSS+ G VP Y K +L+ F + EL + V I
Sbjct: 81 VVSSLLG-RVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNVAI 124
>Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 169
Score = 35.1 bits (77), Expect = 0.30
Identities = 26/107 (24%), Positives = 53/107 (49%), Gaps = 12/107 (11%)
Frame = -3
Query: 638 ECAQVGKKPLIIKADISNDEEAKTIVQQTIDAFGKLDVLINNAGM---NKSGSLLAG--N 474
+ ++G + AD++++++ +T + FG++DV +N AG+ +K+ +L G +
Sbjct: 50 QAKKLGNNCVFAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTH 109
Query: 473 LLESYDAVTATNLRAVILITSLAAPHLIET-------KGNIINVSSI 354
LE + V NL + L A + + +G IIN +S+
Sbjct: 110 TLEDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASV 156
>AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein.
Length = 198
Score = 35.1 bits (77), Expect = 0.30
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 5/93 (5%)
Frame = -3
Query: 527 VLINNAGMNKSGSLLAGNLLESYDAVT--ATNLRAVILITSLAAPHLIETKG---NIINV 363
+LINNAG S +L +S A NL +++ +TS ++ G ++N+
Sbjct: 96 LLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNI 155
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALE 264
SS+ + P G+ YC GKA+ + + +ALE
Sbjct: 156 SSLCA-LQPFKGWALYCAGKAARDMLFQVLALE 187
>AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase
protein.
Length = 198
Score = 35.1 bits (77), Expect = 0.30
Identities = 28/93 (30%), Positives = 47/93 (50%), Gaps = 5/93 (5%)
Frame = -3
Query: 527 VLINNAGMNKSGSLLAGNLLESYDAVT--ATNLRAVILITSLAAPHLIETKG---NIINV 363
+LINNAG S +L +S A NL +++ +TS ++ G ++N+
Sbjct: 96 LLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNI 155
Query: 362 SSIGGTMVPMPGFLAYCMGKASLNHFTRGIALE 264
SS+ + P G+ YC GKA+ + + +ALE
Sbjct: 156 SSLCA-LQPFKGWALYCAGKAARDMLFQVLALE 187
>AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein.
Length = 377
Score = 34.7 bits (76), Expect = 0.40
Identities = 47/203 (23%), Positives = 85/203 (41%), Gaps = 16/203 (7%)
Frame = -3
Query: 764 KVVLVTXXXXXXXXXXAVHFAKEGADVAIVGRNVTKLDNVARECAQV-GKKPLIIKA-DI 591
+ +VT A+ A+ GA V + R+ + + A + Q G +I A D+
Sbjct: 37 RTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNNEVIFMALDL 96
Query: 590 SNDEEAKTIVQQTIDAFGKLDVLINNAGMNKSGSLLAGNLLESYDAVTATNLRAVILITS 411
++ + + + +LD+LI+NAG++ G E+++ + N L+T
Sbjct: 97 ASLASVRAFATAFLSSEPRLDILIHNAGISS-----CGRTREAFNLLLRVNHIGPFLLTH 151
Query: 410 LAAPHLIE-TKGNIINVSSIG---GTM------VPMPGF----LAYCMGKASLNHFTRGI 273
L P L ++ V+S G + P+ G+ AY K + F R +
Sbjct: 152 LLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFAREL 211
Query: 272 ALELAPRGVRANIISPGPVLTDI 204
A +L GV PGPV +++
Sbjct: 212 ANQLEATGVTCYAAHPGPVNSEL 234
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 116,508,233
Number of Sequences: 237096
Number of extensions: 2487608
Number of successful extensions: 6013
Number of sequences better than 10.0: 275
Number of HSP's better than 10.0 without gapping: 5554
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5812
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10092110758
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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