Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV19i07f
(774 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 256 9e-68
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 256 9e-68
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 256 9e-68
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 239 8e-63
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 230 5e-60
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 230 5e-60
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 230 5e-60
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 230 5e-60
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 230 5e-60
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 229 6e-60
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 225 2e-58
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 225 2e-58
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 225 2e-58
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 225 2e-58
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 215 2e-55
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 205 1e-52
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 205 1e-52
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 205 1e-52
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 190 6e-48
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 110 6e-24
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 102 1e-21
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 102 1e-21
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 101 2e-21
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 256 bits (626), Expect = 9e-68
Identities = 118/223 (52%), Positives = 156/223 (69%), Gaps = 1/223 (0%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP+GF++ AA+A+YQIEGAW DGK +IWD H P V +++ GD+A DSY D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAED 1435
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ ++ LGV +YRFS+SW+RILP YINEAG+ YY LID LL +I+P +TIYHWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD+GGW N I+ + +YA VLFQ+ GD+VK WIT+NEP I +QGY GT AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 647 YT-MSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ G A Y+ G N++ AHA+A+H+Y+ +R +Q G ISITI
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITI 1598
Score = 239 bits (585), Expect = 8e-63
Identities = 111/222 (50%), Positives = 142/222 (63%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
F FL+G ++++YQIEGAW+ DGK +IWD H S V DN+TGDIA DSY D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ M+R L V YRFS+SW+RI PT IN GV YYN LI+ L+ NI PM+T++HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD+GGW NP +ID + YA FQ FGDRVK W+T NEP + + GY G P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
G A Y V+ AHA+ YH YD+++R Q G IS+++
Sbjct: 1083 VKDPGWAPYRIAHTVIKAHARVYHTYDEKYRQEQKGVISLSL 1124
Score = 200 bits (489), Expect = 3e-51
Identities = 93/222 (41%), Positives = 130/222 (58%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP+GFL+GA+T ++ +EG W G+ +IWD + + +T ++A+DSY D
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASD 439
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
V ++ L Y+FS+SW+RI P + GVAYYN LID L IEPM T++HWD
Sbjct: 440 VALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWD 499
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD GGW N ++D + DYA F FGDRVK W+T +EP + + GY G P
Sbjct: 500 LPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPG 559
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ GVA + VL AHA+ +H Y+ RP Q G++ I +
Sbjct: 560 ISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIVL 601
Score = 57.2 bits (132), Expect = 6e-08
Identities = 42/154 (27%), Positives = 68/154 (44%)
Frame = +2
Query: 311 VDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWDLPQKLQDM 490
+ +Y+ +SW ++LP +E V Y L+ L ++PM+ ++H LP
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRR 143
Query: 491 GGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPAYTMSGVAD 670
T + D +ADYA F FGD V W T ++ +E+ I L + +
Sbjct: 144 ---TEAF-ADLFADYATFAFHSFGDLVGIWFTFSDLEEV------IKELPHQESRASQLQ 193
Query: 671 YLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
L AH KAY IY + + Q G +S+ +
Sbjct: 194 TLSD-----AHRKAYEIYHESY-AFQGGKLSVVL 221
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 256 bits (626), Expect = 9e-68
Identities = 118/223 (52%), Positives = 156/223 (69%), Gaps = 1/223 (0%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP+GF++ AA+A+YQIEGAW DGK +IWD H P V +++ GD+A DSY D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAED 1435
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ ++ LGV +YRFS+SW+RILP YINEAG+ YY LID LL +I+P +TIYHWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD+GGW N I+ + +YA VLFQ+ GD+VK WIT+NEP I +QGY GT AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 647 YT-MSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ G A Y+ G N++ AHA+A+H+Y+ +R +Q G ISITI
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITI 1598
Score = 238 bits (583), Expect = 1e-62
Identities = 111/222 (50%), Positives = 142/222 (63%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
F FL+G ++++YQIEGAW+ DGK +IWD H S V DN+TGDIA DSY D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ M+R L V YRFS+SW+RI PT IN GV YYN LI+ L+ NI PM+T++HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD+GGW NP +ID + YA FQ FGDRVK W+T NEP + + GY G P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
G A Y V+ AHA+ YH YD+++R Q G IS+++
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKGVISLSL 1124
Score = 200 bits (489), Expect = 3e-51
Identities = 93/222 (41%), Positives = 130/222 (58%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP+GFL+GA+T ++ +EG W G+ +IWD + + +T ++A+DSY D
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASD 439
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
V ++ L Y+FS+SW+RI P + GVAYYN LID L IEPM T++HWD
Sbjct: 440 VALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWD 499
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD GGW N ++D + DYA F FGDRVK W+T +EP + + GY G P
Sbjct: 500 LPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPG 559
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ GVA + VL AHA+ +H Y+ RP Q G++ I +
Sbjct: 560 ISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIVL 601
Score = 57.6 bits (133), Expect = 5e-08
Identities = 43/154 (27%), Positives = 68/154 (44%)
Frame = +2
Query: 311 VDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWDLPQKLQDM 490
+ +Y+ +SW ++LP +E V Y L+ L ++PM+ ++H LP
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRR 143
Query: 491 GGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPAYTMSGVAD 670
T + D +ADYA F FGD V W T ++ +E+ I L + +
Sbjct: 144 ---TEAF-ADLFADYATFAFHSFGDLVGIWFTFSDLEEV------IKELPHQESRASQLQ 193
Query: 671 YLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
L AH KAY IY + + Q G +SI +
Sbjct: 194 TLSD-----AHRKAYEIYHESY-AFQGGKLSIVL 221
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 256 bits (626), Expect = 9e-68
Identities = 118/223 (52%), Positives = 156/223 (69%), Gaps = 1/223 (0%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP+GF++ AA+A+YQIEGAW DGK +IWD H P V +++ GD+A DSY D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAED 1435
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ ++ LGV +YRFS+SW+RILP YINEAG+ YY LID LL +I+P +TIYHWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD+GGW N I+ + +YA VLFQ+ GD+VK WIT+NEP I +QGY GT AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 647 YT-MSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ G A Y+ G N++ AHA+A+H+Y+ +R +Q G ISITI
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISITI 1598
Score = 238 bits (583), Expect = 1e-62
Identities = 111/222 (50%), Positives = 142/222 (63%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
F FL+G ++++YQIEGAW+ DGK +IWD H S V DN+TGDIA DSY D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ M+R L V YRFS+SW+RI PT IN GV YYN LI+ L+ NI PM+T++HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD+GGW NP +ID + YA FQ FGDRVK W+T NEP + + GY G P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
G A Y V+ AHA+ YH YD+++R Q G IS+++
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKGVISLSL 1124
Score = 200 bits (489), Expect = 3e-51
Identities = 93/222 (41%), Positives = 130/222 (58%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP+GFL+GA+T ++ +EG W G+ +IWD + + +T ++A+DSY D
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASD 439
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
V ++ L Y+FS+SW+RI P + GVAYYN LID L IEPM T++HWD
Sbjct: 440 VALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWD 499
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD GGW N ++D + DYA F FGDRVK W+T +EP + + GY G P
Sbjct: 500 LPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPG 559
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ GVA + VL AHA+ +H Y+ RP Q G++ I +
Sbjct: 560 ISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGIVL 601
Score = 57.2 bits (132), Expect = 6e-08
Identities = 42/154 (27%), Positives = 68/154 (44%)
Frame = +2
Query: 311 VDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWDLPQKLQDM 490
+ +Y+ +SW ++LP +E V Y L+ L ++PM+ ++H LP
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRR 143
Query: 491 GGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPAYTMSGVAD 670
T + D +ADYA F FGD V W T ++ +E+ I L + +
Sbjct: 144 ---TEAF-ADLFADYATFAFHSFGDLVGIWFTFSDLEEV------IKELPHQESRASQLQ 193
Query: 671 YLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
L AH KAY IY + + Q G +S+ +
Sbjct: 194 TLSD-----AHRKAYEIYHESY-AFQGGKLSVVL 221
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 239 bits (585), Expect = 8e-63
Identities = 111/222 (50%), Positives = 142/222 (63%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
F FL+G ++++YQIEGAW+ DGK +IWD H S V DN+TGDIA DSY D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ M+R L V YRFS+SW+RI PT IN GV YYN LI+ L+ NI PM+T++HWD
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 454
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD+GGW NP +ID + YA FQ FGDRVK W+T NEP + + GY G P
Sbjct: 455 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 514
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
G A Y V+ AHA+ YH YD+++R Q G IS+++
Sbjct: 515 VKDPGWAPYRIAHTVIKAHARVYHTYDEKYRQEQKGVISLSL 556
Score = 220 bits (537), Expect = 5e-57
Identities = 99/181 (54%), Positives = 128/181 (70%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP+GF++ AA+A+YQIEGAW DGK +IWD H P V +++ GD+A DSY D
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAED 867
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ ++ LGV +YRFS+SW+RILP YINEAG+ YY LID LL +I+P +TIYHWD
Sbjct: 868 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 927
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ LQD+GGW N I+ + +YA VLFQ+ GD+VK WIT+NEP I +QGY GT AP
Sbjct: 928 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPV 987
Query: 647 Y 649
+
Sbjct: 988 H 988
Score = 32.3 bits (70), Expect = 2.0
Identities = 12/28 (42%), Positives = 18/28 (64%)
Frame = +2
Query: 689 VLLAHAKAYHIYDKEFRPTQNGNISITI 772
VL AHA+ +H Y+ RP Q G++ I +
Sbjct: 6 VLKAHARTWHHYNSHHRPQQQGHVGIVL 33
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 230 bits (562), Expect = 5e-60
Identities = 99/222 (44%), Positives = 143/222 (64%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
G Y N++ AHA+++H YD FR Q G +S+++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSL 224
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 230 bits (562), Expect = 5e-60
Identities = 99/222 (44%), Positives = 143/222 (64%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
G Y N++ AHA+++H YD FR Q G +S+++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSL 224
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 230 bits (562), Expect = 5e-60
Identities = 99/222 (44%), Positives = 143/222 (64%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
G Y N++ AHA+++H YD FR Q G +S+++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSL 224
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 230 bits (562), Expect = 5e-60
Identities = 99/222 (44%), Positives = 143/222 (64%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
G Y N++ AHA+++H YD FR Q G +S+++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSL 224
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 230 bits (562), Expect = 5e-60
Identities = 99/222 (44%), Positives = 143/222 (64%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
G Y N++ AHA+++H YD FR Q G +S+++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSL 224
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 229 bits (561), Expect = 6e-60
Identities = 99/222 (44%), Positives = 143/222 (64%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 467 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 646
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 647 YTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
G Y N++ AHA+++H YD FR Q G +S+++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLSL 224
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 225 bits (549), Expect = 2e-58
Identities = 106/238 (44%), Positives = 143/238 (60%), Gaps = 16/238 (6%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADN---------------S 241
FP GFL+ +A+YQ EG W GK +IWD H +P D+ +
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 242 TGDIANDSYKLYKRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDEL 421
TGD+A+DSY RD E +RELGV +YRFS+SW R+LP N G+ YY L++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 422 LKYNIEPMLTIYHWDLPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEP 598
+ ++P++T+YHWDLPQ+LQD GGW N + D + DYA + F+ FG +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 599 KEICFQGYAIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ + GYA G LAP S YL N+LLAHAK +H+Y+ FRPTQ G +SI +
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIAL 298
Score = 110 bits (264), Expect = 6e-24
Identities = 60/167 (35%), Positives = 92/167 (55%), Gaps = 5/167 (2%)
Frame = +2
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY--- 457
+ +++E+ V ++RFS+ W ILP +N + YY + EL++ NI P++ ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 458 --HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIG 631
+ LP+ L G W NPY +A+YAR+ FQ+ G VK WIT+NEP
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP----------- 690
Query: 632 TLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
YT + Y G N+L AHA A+H+Y+++FR QNG ISI +
Sbjct: 691 -----YTRN--MTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIAL 730
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 225 bits (549), Expect = 2e-58
Identities = 106/238 (44%), Positives = 143/238 (60%), Gaps = 16/238 (6%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADN---------------S 241
FP GFL+ +A+YQ EG W GK +IWD H +P D+ +
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 242 TGDIANDSYKLYKRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDEL 421
TGD+A+DSY RD E +RELGV +YRFS+SW R+LP N G+ YY L++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 422 LKYNIEPMLTIYHWDLPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEP 598
+ ++P++T+YHWDLPQ+LQD GGW N + D + DYA + F+ FG +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 599 KEICFQGYAIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ + GYA G LAP S YL N+LLAHAK +H+Y+ FRPTQ G +SI +
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIAL 298
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 225 bits (549), Expect = 2e-58
Identities = 106/238 (44%), Positives = 143/238 (60%), Gaps = 16/238 (6%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADN---------------S 241
FP GFL+ +A+YQ EG W GK +IWD H +P D+ +
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 242 TGDIANDSYKLYKRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDEL 421
TGD+A+DSY RD E +RELGV +YRFS+SW R+LP N G+ YY L++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 422 LKYNIEPMLTIYHWDLPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEP 598
+ ++P++T+YHWDLPQ+LQD GGW N + D + DYA + F+ FG +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 599 KEICFQGYAIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ + GYA G LAP S YL N+LLAHAK +H+Y+ FRPTQ G +SI +
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIAL 298
Score = 110 bits (264), Expect = 6e-24
Identities = 60/167 (35%), Positives = 92/167 (55%), Gaps = 5/167 (2%)
Frame = +2
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY--- 457
+ +++E+ V ++RFS+ W ILP +N + YY + EL++ NI P++ ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 458 --HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIG 631
+ LP+ L G W NPY +A+YAR+ FQ+ G VK WIT+NEP
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP----------- 690
Query: 632 TLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
YT + Y G N+L AHA A+H+Y+++FR QNG ISI +
Sbjct: 691 -----YTRN--MTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIAL 730
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 225 bits (549), Expect = 2e-58
Identities = 106/238 (44%), Positives = 143/238 (60%), Gaps = 16/238 (6%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADN---------------S 241
FP GFL+ +A+YQ EG W GK +IWD H +P D+ +
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 242 TGDIANDSYKLYKRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDEL 421
TGD+A+DSY RD E +RELGV +YRFS+SW R+LP N G+ YY L++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 422 LKYNIEPMLTIYHWDLPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEP 598
+ ++P++T+YHWDLPQ+LQD GGW N + D + DYA + F+ FG +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 599 KEICFQGYAIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ + GYA G LAP S YL N+LLAHAK +H+Y+ FRPTQ G +SI +
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSIAL 298
Score = 110 bits (264), Expect = 6e-24
Identities = 60/167 (35%), Positives = 92/167 (55%), Gaps = 5/167 (2%)
Frame = +2
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY--- 457
+ +++E+ V ++RFS+ W ILP +N + YY + EL++ NI P++ ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 458 --HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIG 631
+ LP+ L G W NPY +A+YAR+ FQ+ G VK WIT+NEP
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP----------- 690
Query: 632 TLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
YT + Y G N+L AHA A+H+Y+++FR QNG ISI +
Sbjct: 691 -----YTRN--MTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIAL 730
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 215 bits (524), Expect = 2e-55
Identities = 95/224 (42%), Positives = 143/224 (63%), Gaps = 2/224 (0%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP GF +G +++YQ EGAW+ DGK +IWD H V N T D+A D Y + D
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSF-PDYINEAGVAYYNNLIDELLKYNIEPMLTIYHW 463
+ ++REL V++YRFS+SW R+LPT + +N+ G+ +Y++LID LL NI P++T++HW
Sbjct: 97 IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156
Query: 464 DLPQKLQ-DMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLA 640
DLPQ LQ GGW N + +++ DYA + F+ FGDRVK+WIT ++P+ + +GY G A
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHA 216
Query: 641 PAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
P + G Y +++ AHAK +H Y+ +R Q G + I++
Sbjct: 217 PGLKLRGTGLYKAAHHIIKAHAKTWHSYNTTWRSKQQGLVGISL 260
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 205 bits (501), Expect = 1e-52
Identities = 96/223 (43%), Positives = 138/223 (61%), Gaps = 1/223 (0%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FPK F +G T + Q+EG+W DGK +IWD H + + + + S+ + ++DSY ++D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWD---HFIHTHLKNVSSTNGSSDSYIFLEKD 137
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ + +GV +Y+FS+SW R+ P N G+ YY+ L+D L+ NIEP++T+YHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 467 LPQKLQDM-GGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAP 643
LP LQ+ GGW N IID + DYA FQ FGDRVK WITI+ P + + GY G AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 644 AYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ A Y G N++ AH+K +H Y+ FRP Q G +SIT+
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITL 300
Score = 123 bits (297), Expect = 6e-28
Identities = 63/170 (37%), Positives = 94/170 (55%), Gaps = 5/170 (2%)
Frame = +2
Query: 278 KRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY 457
K+ +EM+ + V +YRF++ W +LPT +N + YY ++ E LK I M+T+Y
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 458 -----HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGY 622
H LP+ L GW NP + + YA + FQ+ GD VK WITINEP
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNR------ 696
Query: 623 AIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
L+ Y SG Y N+L+AHA A+ +YD++FRP+Q G +S+++
Sbjct: 697 ----LSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSL 742
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 205 bits (501), Expect = 1e-52
Identities = 96/223 (43%), Positives = 138/223 (61%), Gaps = 1/223 (0%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FPK F +G T + Q+EG+W DGK +IWD H + + + + S+ + ++DSY ++D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWD---HFIHTHLKNVSSTNGSSDSYIFLEKD 137
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ + +GV +Y+FS+SW R+ P N G+ YY+ L+D L+ NIEP++T+YHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 467 LPQKLQDM-GGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAP 643
LP LQ+ GGW N IID + DYA FQ FGDRVK WITI+ P + + GY G AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 644 AYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ A Y G N++ AH+K +H Y+ FRP Q G +SIT+
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITL 300
Score = 123 bits (297), Expect = 6e-28
Identities = 63/170 (37%), Positives = 94/170 (55%), Gaps = 5/170 (2%)
Frame = +2
Query: 278 KRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY 457
K+ +EM+ + V +YRF++ W +LPT +N + YY ++ E LK I M+T+Y
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 458 -----HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGY 622
H LP+ L GW NP + + YA + FQ+ GD VK WITINEP
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNR------ 696
Query: 623 AIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
L+ Y SG Y N+L+AHA A+ +YD++FRP+Q G +S+++
Sbjct: 697 ----LSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSL 742
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 205 bits (501), Expect = 1e-52
Identities = 96/223 (43%), Positives = 138/223 (61%), Gaps = 1/223 (0%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FPK F +G T + Q+EG+W DGK +IWD H + + + + S+ + ++DSY ++D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWD---HFIHTHLKNVSSTNGSSDSYIFLEKD 137
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 466
+ + +GV +Y+FS+SW R+ P N G+ YY+ L+D L+ NIEP++T+YHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 467 LPQKLQDM-GGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAP 643
LP LQ+ GGW N IID + DYA FQ FGDRVK WITI+ P + + GY G AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 644 AYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
+ A Y G N++ AH+K +H Y+ FRP Q G +SIT+
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSITL 300
Score = 123 bits (297), Expect = 6e-28
Identities = 63/170 (37%), Positives = 94/170 (55%), Gaps = 5/170 (2%)
Frame = +2
Query: 278 KRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY 457
K+ +EM+ + V +YRF++ W +LPT +N + YY ++ E LK I M+T+Y
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 458 -----HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGY 622
H LP+ L GW NP + + YA + FQ+ GD VK WITINEP
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNR------ 696
Query: 623 AIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
L+ Y SG Y N+L+AHA A+ +YD++FRP+Q G +S+++
Sbjct: 697 ----LSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLSL 742
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 190 bits (462), Expect = 6e-48
Identities = 92/213 (43%), Positives = 124/213 (58%), Gaps = 16/213 (7%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADN---------------S 241
FP GFL+ +A+YQ EG W GK +IWD H +P D+ +
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 242 TGDIANDSYKLYKRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDEL 421
TGD+A+DSY RD E +RELGV +YRFS+SW R+LP N G+ YY L++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 422 LKYNIEPMLTIYHWDLPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEP 598
+ ++P++T+YHWDLPQ+LQD GGW N + D + DYA + F+ FG +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 599 KEICFQGYAIGTLAPAYTMSGVADYLCGKNVLL 697
+ + GYA G LAP S YL N+LL
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLL 273
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 110 bits (264), Expect = 6e-24
Identities = 60/167 (35%), Positives = 92/167 (55%), Gaps = 5/167 (2%)
Frame = +2
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY--- 457
+ +++E+ V ++RFS+ W ILP +N + YY + EL++ NI P++ ++
Sbjct: 309 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 368
Query: 458 --HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIG 631
+ LP+ L G W NPY +A+YAR+ FQ+ G VK WIT+NEP
Sbjct: 369 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP----------- 417
Query: 632 TLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDKEFRPTQNGNISITI 772
YT + Y G N+L AHA A+H+Y+++FR QNG ISI +
Sbjct: 418 -----YTRN--MTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISIAL 457
Score = 39.1 bits (87), Expect = 0.017
Identities = 14/25 (56%), Positives = 19/25 (76%)
Frame = +2
Query: 698 AHAKAYHIYDKEFRPTQNGNISITI 772
AHAK +H+Y+ FRPTQ G +SI +
Sbjct: 1 AHAKVWHLYNTSFRPTQGGQVSIAL 25
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 102 bits (245), Expect = 1e-21
Identities = 43/95 (45%), Positives = 64/95 (67%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGV 391
++ I++LG+ +YRFS+SW+R+LP +IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 102 bits (245), Expect = 1e-21
Identities = 43/95 (45%), Positives = 64/95 (67%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGV 391
++ I++LG+ +YRFS+SW+R+LP +IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 101 bits (243), Expect = 2e-21
Identities = 43/95 (45%), Positives = 64/95 (67%)
Frame = +2
Query: 107 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 286
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 287 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGV 391
++ I++LG+ +YRFS+SW+R+LP +IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 111,823,687
Number of Sequences: 237096
Number of extensions: 2415977
Number of successful extensions: 4758
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 4198
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4717
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9367263024
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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