Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV19d08r
(898 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein. 324 2e-88
J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched ... 324 2e-88
BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branch... 324 2e-88
BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branch... 324 2e-88
M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylas... 322 8e-88
AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branch... 322 1e-87
L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide succinyl... 136 1e-31
BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide S-succ... 136 1e-31
BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide S-succ... 136 1e-31
AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein. 136 1e-31
D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide succinyl... 135 2e-31
CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein. 134 3e-31
Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 ... 133 9e-31
D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial dihydrolipo... 133 9e-31
BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide S-acet... 133 9e-31
AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide S-acet... 132 2e-30
J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide acetyltr... 127 5e-29
S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate dehyd... 124 4e-28
Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein. 105 2e-22
U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase co... 105 2e-22
U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl tr... 105 2e-22
AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing compo... 105 2e-22
AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide dehydr... 105 2e-22
BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase ... 105 2e-22
M19301-1|AAA59200.1| 315|Homo sapiens DBT protein. 89 3e-17
AL445928-10|CAH72258.1| 320|Homo sapiens dihydrolipoamide branc... 89 3e-17
X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide S-acetyl... 71 6e-12
X53416-1|CAA37495.1| 2647|Homo sapiens protein ( Human mRNA for ... 31 4.3
L44140-1|AAA92644.1| 2647|Homo sapiens filamin protein. 31 4.3
BX936346-3|CAI43225.1| 2647|Homo sapiens filamin A, alpha (actin... 31 4.3
BX936346-2|CAI43227.1| 2639|Homo sapiens filamin A, alpha (actin... 31 4.3
BX936346-1|CAI43226.1| 2607|Homo sapiens filamin A, alpha (actin... 31 4.3
BX664723-3|CAI43197.1| 2647|Homo sapiens filamin A, alpha (actin... 31 4.3
BX664723-2|CAI43199.1| 2639|Homo sapiens filamin A, alpha (actin... 31 4.3
BX664723-1|CAI43198.1| 2607|Homo sapiens filamin A, alpha (actin... 31 4.3
AK090427-1|BAC03408.1| 2651|Homo sapiens FLJ00343 protein protein. 31 4.3
AK074048-1|BAB84874.1| 1455|Homo sapiens FLJ00119 protein protein. 31 4.3
AB191260-1|BAD52436.1| 2620|Homo sapiens filamin A protein. 31 4.3
AB191259-1|BAD52435.1| 2612|Homo sapiens filamin A protein. 31 4.3
>X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein.
Length = 482
Score = 324 bits (797), Expect = 2e-88
Identities = 160/295 (54%), Positives = 217/295 (73%), Gaps = 7/295 (2%)
Frame = -2
Query: 894 LSAVKATGRNGRVLKEDMLSHLNINSD----DSNEVVL---PGSVRAVEIPVTKAQARVE 736
LS V +G++GR+LKED+L++L + S +V + P + + +P+ ++ V
Sbjct: 188 LSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVF 247
Query: 735 LALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKLVESRAALKKQAEERGVRLT 556
+DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+LV+ R LK A RG++L+
Sbjct: 248 TG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLS 306
Query: 555 YMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKS 376
+MP +KAASL L PILN+S+D +C+N+ YKASHNIG+AMDT GL+VP +KN+QI S
Sbjct: 307 FMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICS 366
Query: 375 ILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKI 196
I +IA ELN LQ+ GS GQL DLTGGTFT+SNIG +GGT+ KPVI PP+VAIGALG I
Sbjct: 367 IFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSI 426
Query: 195 QVLPRFDSQGNVVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLLDL 31
+ +PRF+ +G V KA I++VSWSADHRVIDG TM+RFSN K+YLE+P +LLDL
Sbjct: 427 KAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLDL 481
>J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched chain
acyltransferase mRNA, complete cds. ).
Length = 477
Score = 324 bits (797), Expect = 2e-88
Identities = 160/295 (54%), Positives = 217/295 (73%), Gaps = 7/295 (2%)
Frame = -2
Query: 894 LSAVKATGRNGRVLKEDMLSHLNINSD----DSNEVVL---PGSVRAVEIPVTKAQARVE 736
LS V +G++GR+LKED+L++L + S +V + P + + +P+ ++ V
Sbjct: 183 LSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVF 242
Query: 735 LALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKLVESRAALKKQAEERGVRLT 556
+DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+LV+ R LK A RG++L+
Sbjct: 243 TG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLS 301
Query: 555 YMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKS 376
+MP +KAASL L PILN+S+D +C+N+ YKASHNIG+AMDT GL+VP +KN+QI S
Sbjct: 302 FMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICS 361
Query: 375 ILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKI 196
I +IA ELN LQ+ GS GQL DLTGGTFT+SNIG +GGT+ KPVI PP+VAIGALG I
Sbjct: 362 IFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSI 421
Query: 195 QVLPRFDSQGNVVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLLDL 31
+ +PRF+ +G V KA I++VSWSADHRVIDG TM+RFSN K+YLE+P +LLDL
Sbjct: 422 KAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLDL 476
>BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase (E2 component of branched chain ke
protein.
Length = 482
Score = 324 bits (797), Expect = 2e-88
Identities = 160/295 (54%), Positives = 217/295 (73%), Gaps = 7/295 (2%)
Frame = -2
Query: 894 LSAVKATGRNGRVLKEDMLSHLNINSD----DSNEVVL---PGSVRAVEIPVTKAQARVE 736
LS V +G++GR+LKED+L++L + S +V + P + + +P+ ++ V
Sbjct: 188 LSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVF 247
Query: 735 LALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKLVESRAALKKQAEERGVRLT 556
+DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+LV+ R LK A RG++L+
Sbjct: 248 TG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLS 306
Query: 555 YMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKS 376
+MP +KAASL L PILN+S+D +C+N+ YKASHNIG+AMDT GL+VP +KN+QI S
Sbjct: 307 FMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICS 366
Query: 375 ILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKI 196
I +IA ELN LQ+ GS GQL DLTGGTFT+SNIG +GGT+ KPVI PP+VAIGALG I
Sbjct: 367 IFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSI 426
Query: 195 QVLPRFDSQGNVVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLLDL 31
+ +PRF+ +G V KA I++VSWSADHRVIDG TM+RFSN K+YLE+P +LLDL
Sbjct: 427 KAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLDL 481
>BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 324 bits (797), Expect = 2e-88
Identities = 160/295 (54%), Positives = 217/295 (73%), Gaps = 7/295 (2%)
Frame = -2
Query: 894 LSAVKATGRNGRVLKEDMLSHLNINSD----DSNEVVL---PGSVRAVEIPVTKAQARVE 736
LS V +G++GR+LKED+L++L + S +V + P + + +P+ ++ V
Sbjct: 188 LSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVF 247
Query: 735 LALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKLVESRAALKKQAEERGVRLT 556
+DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+LV+ R LK A RG++L+
Sbjct: 248 TG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLS 306
Query: 555 YMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKS 376
+MP +KAASL L PILN+S+D +C+N+ YKASHNIG+AMDT GL+VP +KN+QI S
Sbjct: 307 FMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICS 366
Query: 375 ILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKI 196
I +IA ELN LQ+ GS GQL DLTGGTFT+SNIG +GGT+ KPVI PP+VAIGALG I
Sbjct: 367 IFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSI 426
Query: 195 QVLPRFDSQGNVVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLLDL 31
+ +PRF+ +G V KA I++VSWSADHRVIDG TM+RFSN K+YLE+P +LLDL
Sbjct: 427 KAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLDL 481
>M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylase
protein.
Length = 477
Score = 322 bits (792), Expect = 8e-88
Identities = 159/295 (53%), Positives = 217/295 (73%), Gaps = 7/295 (2%)
Frame = -2
Query: 894 LSAVKATGRNGRVLKEDMLSHLNINSD----DSNEVVL---PGSVRAVEIPVTKAQARVE 736
LS V +G++GR+LKED+L++L + S +V + P + + +P+ ++ V
Sbjct: 183 LSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVF 242
Query: 735 LALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKLVESRAALKKQAEERGVRLT 556
+DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+LV+ R LK A RG++L+
Sbjct: 243 TG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLS 301
Query: 555 YMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKS 376
+MP +KAASL L PILN+S+D +C+N+ YKASHNIG+AMDT G++VP +KN+QI S
Sbjct: 302 FMPFFLKAASLGLLPFPILNASVDENCQNITYKASHNIGIAMDTEQGVIVPNVKNVQICS 361
Query: 375 ILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKI 196
I +IA ELN LQ+ GS GQL DLTGGTFT+SNIG +GGT+ KPVI PP+VAIGALG I
Sbjct: 362 IFDIATELNRLQKLGSVGQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSI 421
Query: 195 QVLPRFDSQGNVVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLLDL 31
+ +PRF+ +G V KA I++VSWSADHRVIDG TM+RFSN K+YLE+P +LLDL
Sbjct: 422 KAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLDL 476
>AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 322 bits (791), Expect = 1e-87
Identities = 159/295 (53%), Positives = 216/295 (73%), Gaps = 7/295 (2%)
Frame = -2
Query: 894 LSAVKATGRNGRVLKEDMLSHLNINSD----DSNEVVL---PGSVRAVEIPVTKAQARVE 736
LS V +G++GR+LKED+L++L + S +V + P + + +P+ ++ V
Sbjct: 188 LSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVF 247
Query: 735 LALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKLVESRAALKKQAEERGVRLT 556
+DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+LV+ R LK A RG++L+
Sbjct: 248 TG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLS 306
Query: 555 YMPIIIKAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKS 376
+MP +KAASL L PILN+S+D +C+N+ YKASHNIG+AMDT GL+VP +KN+QI S
Sbjct: 307 FMPFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICS 366
Query: 375 ILEIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKI 196
I +IA ELN LQ+ GS QL DLTGGTFT+SNIG +GGT+ KPVI PP+VAIGALG I
Sbjct: 367 IFDIATELNRLQKLGSVSQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSI 426
Query: 195 QVLPRFDSQGNVVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLLDL 31
+ +PRF+ +G V KA I++VSWSADHRVIDG TM+RFSN K+YLE+P +LLDL
Sbjct: 427 KAIPRFNQKGEVYKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLLDL 481
>L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 136 bits (329), Expect = 1e-31
Identities = 73/204 (35%), Positives = 123/204 (60%), Gaps = 2/204 (0%)
Frame = -2
Query: 636 DEYNVTKLVESRAALKKQ-AEERGVRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 460
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 459 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 280
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 279 SNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQGNVVKAH-ILSVSWSADHRVIDG 103
SN G+ G + P+I PPQ AI LG + R + G V+ ++ V+ + DHR+IDG
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI--LGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDG 429
Query: 102 VTMARFSNHLKNYLEDPYILLLDL 31
F +K +EDP +LLLDL
Sbjct: 430 REAVTFLRKIKAAVEDPRVLLLDL 453
>BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 136 bits (329), Expect = 1e-31
Identities = 73/204 (35%), Positives = 123/204 (60%), Gaps = 2/204 (0%)
Frame = -2
Query: 636 DEYNVTKLVESRAALKKQ-AEERGVRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 460
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 459 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 280
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 279 SNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQGNVVKAH-ILSVSWSADHRVIDG 103
SN G+ G + P+I PPQ AI LG + R + G V+ ++ V+ + DHR+IDG
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI--LGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDG 429
Query: 102 VTMARFSNHLKNYLEDPYILLLDL 31
F +K +EDP +LLLDL
Sbjct: 430 REAVTFLRKIKAAVEDPRVLLLDL 453
>BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 136 bits (329), Expect = 1e-31
Identities = 73/204 (35%), Positives = 123/204 (60%), Gaps = 2/204 (0%)
Frame = -2
Query: 636 DEYNVTKLVESRAALKKQ-AEERGVRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 460
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 459 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 280
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 279 SNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQGNVVKAH-ILSVSWSADHRVIDG 103
SN G+ G + P+I PPQ AI LG + R + G V+ ++ V+ + DHR+IDG
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI--LGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDG 429
Query: 102 VTMARFSNHLKNYLEDPYILLLDL 31
F +K +EDP +LLLDL
Sbjct: 430 REAVTFLRKIKAAVEDPRVLLLDL 453
>AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein.
Length = 453
Score = 136 bits (329), Expect = 1e-31
Identities = 73/204 (35%), Positives = 123/204 (60%), Gaps = 2/204 (0%)
Frame = -2
Query: 636 DEYNVTKLVESRAALKKQ-AEERGVRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 460
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 459 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 280
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 279 SNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQGNVVKAH-ILSVSWSADHRVIDG 103
SN G+ G + P+I PPQ AI LG + R + G V+ ++ V+ + DHR+IDG
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI--LGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDG 429
Query: 102 VTMARFSNHLKNYLEDPYILLLDL 31
F +K +EDP +LLLDL
Sbjct: 430 REAVTFLRKIKAAVEDPRVLLLDL 453
>D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 135 bits (326), Expect = 2e-31
Identities = 73/204 (35%), Positives = 122/204 (59%), Gaps = 2/204 (0%)
Frame = -2
Query: 636 DEYNVTKLVESRAALKKQ-AEERGVRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 460
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 459 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 280
+I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 TDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 279 SNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQGNVVKAH-ILSVSWSADHRVIDG 103
SN G+ G + P+I PPQ AI LG + R + G V+ ++ V+ + DHR+IDG
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI--LGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDG 429
Query: 102 VTMARFSNHLKNYLEDPYILLLDL 31
F +K +EDP +LLLDL
Sbjct: 430 REAVTFLRKIKAAVEDPRVLLLDL 453
>CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein.
Length = 453
Score = 134 bits (325), Expect = 3e-31
Identities = 72/204 (35%), Positives = 122/204 (59%), Gaps = 2/204 (0%)
Frame = -2
Query: 636 DEYNVTKLVESRAALKKQ-AEERGVRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 460
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 459 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 280
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 279 SNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQGNVVKAH-ILSVSWSADHRVIDG 103
SN G+ G + P+I PPQ AI LG + R + G V+ ++ V+ + DHR+IDG
Sbjct: 372 SNGGVFGSLFGTPIINPPQSAI--LGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDG 429
Query: 102 VTMARFSNHLKNYLEDPYILLLDL 31
F +K +EDP +LL DL
Sbjct: 430 REAVTFLRKIKAAVEDPRVLLFDL 453
>Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 to
561) protein.
Length = 615
Score = 133 bits (321), Expect = 9e-31
Identities = 91/292 (31%), Positives = 159/292 (54%), Gaps = 5/292 (1%)
Frame = -2
Query: 897 DLSAVKATGRNGRVLKEDMLSHLNINSDDSNEVVLPGSVRAVEIPVTKAQARVELALEDK 718
DL+ VK TG +GR+ K+D+ S + + V+P P A V +
Sbjct: 339 DLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVP--------PTGPGMAPVPTGVFTD 390
Query: 717 VVPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGVRLTYMPII 541
+ P++ +R + + + ++ + IPH+ S + N+ +++ R L K E R +++ I
Sbjct: 391 I-PISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS-KISVNDFI 448
Query: 540 IKAASLSLSYLPILNSSLDSSCENLIYKASH--NIGVAMDTPNGLVVPVIKNIQIKSILE 367
IKA++L+ +P NSS + + + +H ++ VA+ TP GL+ P++ N IK +
Sbjct: 449 IKASALACLKVPEANSSWMDT----VIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVET 504
Query: 366 IAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALG--KIQ 193
IA ++ +L K +G+L ++ GGTFTISN+G+ G +I PPQ I A+G + +
Sbjct: 505 IANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDK 564
Query: 192 VLPRFDSQGNVVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLL 37
++P + +G V A ++SV+ S DHRV+DG A++ + YLE P +LL
Sbjct: 565 LVPADNEKGFDV-ASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL 615
>D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial
dihydrolipoamide succinyltransferase protein.
Length = 453
Score = 133 bits (321), Expect = 9e-31
Identities = 72/204 (35%), Positives = 122/204 (59%), Gaps = 2/204 (0%)
Frame = -2
Query: 636 DEYNVTKLVESRAALKKQ-AEERGVRLTYMPIIIKAASLSLSYLPILNSSLDSSCENLIY 460
+E +++ + E RA K+ ++ ++L +M +KA++ +L P++N+ +D + + ++Y
Sbjct: 252 NEIDMSNIQEMRARHKEAFLKKHNLKLGFMSAFVKASAFALQEQPVVNAVIDDTTKEVVY 311
Query: 459 KASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTLQEKGSKGQLGLNDLTGGTFTI 280
+ +I VA+ TP GLVVPVI+N++ + +I + + L EK K +L + D+ GGTFTI
Sbjct: 312 RDYIDISVAVATPRGLVVPVIRNVEAMNFADIERTITELGEKARKNELAIEDMDGGTFTI 371
Query: 279 SNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQGNVVKAH-ILSVSWSADHRVIDG 103
SN G+ G + +I PPQ AI LG + R + G V+ ++ V+ + DHR+IDG
Sbjct: 372 SNGGVFGSLFGTTIINPPQSAI--LGMHGIFDRPVAIGGKVEVRPMMYVALTYDHRLIDG 429
Query: 102 VTMARFSNHLKNYLEDPYILLLDL 31
F +K +EDP +LLLDL
Sbjct: 430 REAVTFLRKIKAAVEDPRVLLLDL 453
>BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 133 bits (321), Expect = 9e-31
Identities = 91/292 (31%), Positives = 159/292 (54%), Gaps = 5/292 (1%)
Frame = -2
Query: 897 DLSAVKATGRNGRVLKEDMLSHLNINSDDSNEVVLPGSVRAVEIPVTKAQARVELALEDK 718
DL+ VK TG +GR+ K+D+ S + + V+P P A V +
Sbjct: 371 DLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVP--------PTGPGMAPVPTGVFTD 422
Query: 717 VVPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGVRLTYMPII 541
+ P++ +R + + + ++ + IPH+ S + N+ +++ R L K E R +++ I
Sbjct: 423 I-PISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS-KISVNDFI 480
Query: 540 IKAASLSLSYLPILNSSLDSSCENLIYKASH--NIGVAMDTPNGLVVPVIKNIQIKSILE 367
IKA++L+ +P NSS + + + +H ++ VA+ TP GL+ P++ N IK +
Sbjct: 481 IKASALACLKVPEANSSWMDT----VIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVET 536
Query: 366 IAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALG--KIQ 193
IA ++ +L K +G+L ++ GGTFTISN+G+ G +I PPQ I A+G + +
Sbjct: 537 IANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDK 596
Query: 192 VLPRFDSQGNVVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLL 37
++P + +G V A ++SV+ S DHRV+DG A++ + YLE P +LL
Sbjct: 597 LVPADNEKGFDV-ASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL 647
>AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 132 bits (319), Expect = 2e-30
Identities = 91/292 (31%), Positives = 158/292 (54%), Gaps = 5/292 (1%)
Frame = -2
Query: 897 DLSAVKATGRNGRVLKEDMLSHLNINSDDSNEVVLPGSVRAVEIPVTKAQARVELALEDK 718
DL+ VK TG +GR+ K+D+ S + + V+P P A V +
Sbjct: 371 DLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVP--------PTGPGMAPVPTGVFTD 422
Query: 717 VVPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGVRLTYMPII 541
+ P++ +R + + + ++ + IPH+ S N+ +++ R L K E R +++ I
Sbjct: 423 I-PISNIRRVIAQRLMQSKQTIPHYYLSINVNMGEVLLVRKELNKILEGRS-KISVNDFI 480
Query: 540 IKAASLSLSYLPILNSSLDSSCENLIYKASH--NIGVAMDTPNGLVVPVIKNIQIKSILE 367
IKA++L+ +P NSS + + + +H ++ VA+ TP GL+ P++ N IK +
Sbjct: 481 IKASALACLKVPEANSSWMDT----VIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVET 536
Query: 366 IAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALG--KIQ 193
IA ++ +L K +G+L ++ GGTFTISN+G+ G +I PPQ I A+G + +
Sbjct: 537 IANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASEDK 596
Query: 192 VLPRFDSQGNVVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLL 37
++P + +G V A ++SV+ S DHRV+DG A++ + YLE P +LL
Sbjct: 597 LVPADNEKGFDV-ASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL 647
>J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide
acetyltransferase protein.
Length = 613
Score = 127 bits (307), Expect = 5e-29
Identities = 93/293 (31%), Positives = 158/293 (53%), Gaps = 6/293 (2%)
Frame = -2
Query: 897 DLSAVKATGRNGRVLKEDMLSHLNINSDDSNEVVLPGSVRAVEIPVTKAQARVELALEDK 718
DL+ VK TG +GR+ K+D+ S + + V+P P A V +
Sbjct: 338 DLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVP--------PTGPGMAPVPTGVFTD 389
Query: 717 VVPVTGFQRAMVKSMTEAMK-IPHF-VFSDEYNVTKLVESRAALKKQAEERGVRLTYMPI 544
+ P++ +R + + + ++ + IPH+ + S +Y LV R L K E R +++
Sbjct: 390 I-PISNIRRVIAQRLMQSKQTIPHYYLLSCKYGEVLLV--RKELNKILEGRS-KISVNDF 445
Query: 543 IIKAASLSLSYLPILNSSLDSSCENLIYKASH--NIGVAMDTPNGLVVPVIKNIQIKSIL 370
IIKA++L+ +P NSS + + + +H ++ VA+ TP GL+ P++ N IK +
Sbjct: 446 IIKASALACLKVPEANSSWMDT----VIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVE 501
Query: 369 EIAQELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALG--KI 196
IA ++ +L K +G+L ++ GGTFTISN+G+ G +I PPQ I A+G +
Sbjct: 502 TIANDVVSLATKAREGKLQPHEFQGGTFTISNLGMFGIKNFSAIINPPQACILAIGASED 561
Query: 195 QVLPRFDSQGNVVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLL 37
+++P + +G V A ++SV+ S DHRV+DG A++ + YLE P +LL
Sbjct: 562 KLVPADNEKGFDV-ASMMSVTLSCDHRVVDGAVGAQWLAEFRKYLEKPITMLL 613
>S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate
dehydrogenase complex dihydrolipoyl succinyltransferase
protein.
Length = 451
Score = 124 bits (299), Expect = 4e-28
Identities = 69/224 (30%), Positives = 121/224 (54%), Gaps = 2/224 (0%)
Frame = -2
Query: 696 QRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQ-AEERGVRLTYMPIIIKAASL 523
++ + + + EA +P +E +V+ + + RA K+ ++ ++L +M +KA++
Sbjct: 230 RQCIAQRLKEAQNTVPMLTIFNEIDVSNIQKMRARHKEAFLKKHNLKLGFMSASVKASAF 289
Query: 522 SLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQELNTL 343
+L P++N+ +D + ++Y+ +I VA+ TP GLVVPVI+N++ + +I Q + L
Sbjct: 290 ALQEQPVVNAVIDDITKEVVYRDYIDISVAVATPQGLVVPVIRNVEAMNYADIEQTITEL 349
Query: 342 QEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQGN 163
EK K + + D+ GGTFTISN G+ G + P+ P +G G G
Sbjct: 350 GEKARKNEFAIEDMDGGTFTISNGGVFGSLFEHPLSTPLSAILGMHGIFDKPVAIG--GK 407
Query: 162 VVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDPYILLLDL 31
V ++ V+ + DHR+IDG F +K +EDP +LL DL
Sbjct: 408 VEVRPMMYVALTYDHRLIDGREAVTFLRKIKAAVEDPRVLLFDL 451
>Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein.
Length = 501
Score = 105 bits (253), Expect = 2e-22
Identities = 69/226 (30%), Positives = 121/226 (53%), Gaps = 5/226 (2%)
Frame = -2
Query: 714 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGVRLTYMPIII 538
+P + +R + K +TE+ +PH + + ++ +++ R L K ++++ II
Sbjct: 278 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 333
Query: 537 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 358
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 391
Query: 357 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 178
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 451
Query: 177 --DSQGN--VVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDP 52
D +GN + + +++V+ S+D RV+D RF K LE+P
Sbjct: 452 TEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase
complex protein X subunit precursor protein.
Length = 501
Score = 105 bits (253), Expect = 2e-22
Identities = 69/226 (30%), Positives = 121/226 (53%), Gaps = 5/226 (2%)
Frame = -2
Query: 714 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGVRLTYMPIII 538
+P + +R + K +TE+ +PH + + ++ +++ R L K ++++ II
Sbjct: 278 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 333
Query: 537 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 358
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 391
Query: 357 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 178
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 451
Query: 177 --DSQGN--VVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDP 52
D +GN + + +++V+ S+D RV+D RF K LE+P
Sbjct: 452 TEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>U79296-1|AAB50223.1| 375|Homo sapiens dihyrolipoamide acetyl
transferase protein.
Length = 375
Score = 105 bits (253), Expect = 2e-22
Identities = 69/226 (30%), Positives = 121/226 (53%), Gaps = 5/226 (2%)
Frame = -2
Query: 714 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGVRLTYMPIII 538
+P + +R + K +TE+ +PH + + ++ +++ R L K ++++ II
Sbjct: 152 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 207
Query: 537 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 358
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 208 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 265
Query: 357 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 178
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 266 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 325
Query: 177 --DSQGN--VVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDP 52
D +GN + + +++V+ S+D RV+D RF K LE+P
Sbjct: 326 TEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 371
>AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing
component X protein.
Length = 501
Score = 105 bits (253), Expect = 2e-22
Identities = 69/226 (30%), Positives = 121/226 (53%), Gaps = 5/226 (2%)
Frame = -2
Query: 714 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGVRLTYMPIII 538
+P + +R + K +TE+ +PH + + ++ +++ R L K ++++ II
Sbjct: 278 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 333
Query: 537 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 358
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 391
Query: 357 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 178
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 451
Query: 177 --DSQGN--VVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDP 52
D +GN + + +++V+ S+D RV+D RF K LE+P
Sbjct: 452 TEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide
dehydrogenase-binding protein protein.
Length = 501
Score = 105 bits (253), Expect = 2e-22
Identities = 69/226 (30%), Positives = 121/226 (53%), Gaps = 5/226 (2%)
Frame = -2
Query: 714 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGVRLTYMPIII 538
+P + +R + K +TE+ +PH + + ++ +++ R L K ++++ II
Sbjct: 278 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 333
Query: 537 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 358
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATDKGLLTPIIKDAAAKGIQEIAD 391
Query: 357 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 178
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 451
Query: 177 --DSQGN--VVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDP 52
D +GN + + +++V+ S+D RV+D RF K LE+P
Sbjct: 452 TEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase
complex, component X protein.
Length = 501
Score = 105 bits (252), Expect = 2e-22
Identities = 69/226 (30%), Positives = 121/226 (53%), Gaps = 5/226 (2%)
Frame = -2
Query: 714 VPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGVRLTYMPIII 538
+P + +R + K +TE+ +PH + + ++ +++ R L K ++++ II
Sbjct: 278 IPASNIRRVIAKRLTESKSTVPHAYATADCDLGAVLKVRQDLVKD----DIKVSVNDFII 333
Query: 537 KAASLSLSYLPILNSSLDSSCENLIYKASHNIGVAMDTPNGLVVPVIKNIQIKSILEIAQ 358
KAA+++L +P +N S D + +I VA+ T GL+ P+IK+ K I EIA
Sbjct: 334 KAAAVTLKQMPDVNVSWDGEGPKQL--PFIDISVAVATVKGLLTPIIKDAAAKGIQEIAD 391
Query: 357 ELNTLQEKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRF 178
+ L +K G+L + GG+F+ISN+G+ G VI PPQ I A+G+ + + +
Sbjct: 392 SVKALSKKARDGKLLPEEYQGGSFSISNLGMFGIDEFTAVINPPQACILAVGRFRPVLKL 451
Query: 177 --DSQGN--VVKAHILSVSWSADHRVIDGVTMARFSNHLKNYLEDP 52
D +GN + + +++V+ S+D RV+D RF K LE+P
Sbjct: 452 TEDEEGNAKLQQRQLITVTMSSDSRVVDDELATRFLKSFKANLENP 497
>M19301-1|AAA59200.1| 315|Homo sapiens DBT protein.
Length = 315
Score = 88.6 bits (210), Expect = 3e-17
Identities = 49/127 (38%), Positives = 81/127 (63%), Gaps = 7/127 (5%)
Frame = -2
Query: 894 LSAVKATGRNGRVLKEDMLSHLNINSD----DSNEVVL---PGSVRAVEIPVTKAQARVE 736
LS V +G++GR+LKED+L++L + S +V + P + + +P+ ++ V
Sbjct: 183 LSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVF 242
Query: 735 LALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKLVESRAALKKQAEERGVRLT 556
+DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+LV+ R LK A RG++L+
Sbjct: 243 TG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLS 301
Query: 555 YMPIIIK 535
+MP +K
Sbjct: 302 FMPFFLK 308
>AL445928-10|CAH72258.1| 320|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 320
Score = 88.6 bits (210), Expect = 3e-17
Identities = 49/127 (38%), Positives = 81/127 (63%), Gaps = 7/127 (5%)
Frame = -2
Query: 894 LSAVKATGRNGRVLKEDMLSHLNINSD----DSNEVVL---PGSVRAVEIPVTKAQARVE 736
LS V +G++GR+LKED+L++L + S +V + P + + +P+ ++ V
Sbjct: 188 LSEVVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVF 247
Query: 735 LALEDKVVPVTGFQRAMVKSMTEAMKIPHFVFSDEYNVTKLVESRAALKKQAEERGVRLT 556
+DK P+ GFQ+AMVK+M+ A+KIPHF + DE ++T+LV+ R LK A RG++L+
Sbjct: 248 TG-KDKTEPIKGFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLS 306
Query: 555 YMPIIIK 535
+MP +K
Sbjct: 307 FMPFFLK 313
>X13822-1|CAA32052.1| 220|Homo sapiens dihydrolipoamide
S-acetyltransferase protein.
Length = 220
Score = 70.9 bits (166), Expect = 6e-12
Identities = 53/197 (26%), Positives = 101/197 (51%), Gaps = 3/197 (1%)
Frame = -2
Query: 897 DLSAVKATGRNGRVLKEDMLSHLNINSDDSNEVVLPGSVRAVEIPVTKAQARVELALEDK 718
DL+ VK TG +GR+ K+D+ S + + V+P P A V +
Sbjct: 35 DLTQVKGTGPDGRITKKDIDSFVPSKVAPAPAAVVP--------PTGPGMAPVPTGVFTD 86
Query: 717 VVPVTGFQRAMVKSMTEAMK-IPHFVFSDEYNVTKLVESRAALKKQAEERGVRLTYMPII 541
+ P++ +R + + + ++ + IPH+ S + N+ +++ R L K E R +++ I
Sbjct: 87 I-PISNIRRVIAQRLMQSKQTIPHYYLSIDVNMGEVLLVRKELNKILEGRS-KISVNDFI 144
Query: 540 IKAASLSLSYLPILNSSLDSSCENLIYKASH--NIGVAMDTPNGLVVPVIKNIQIKSILE 367
IK ++L+ +P NSS + + + +H ++ VA+ TP GL+ P++ N IK +
Sbjct: 145 IKRSALACLKVPEANSSWMDT----VIRQNHVVDVSVAVSTPAGLITPIVFNAHIKGVET 200
Query: 366 IAQELNTLQEKGSKGQL 316
IA ++ +L K +G+L
Sbjct: 201 IANDVVSLATKAREGKL 217
>X53416-1|CAA37495.1| 2647|Homo sapiens protein ( Human mRNA for
actin-binding protein (filamin) (ABP-280). ).
Length = 2647
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1257
>L44140-1|AAA92644.1| 2647|Homo sapiens filamin protein.
Length = 2647
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1257
>BX936346-3|CAI43225.1| 2647|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2647
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1257
>BX936346-2|CAI43227.1| 2639|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2639
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1257
>BX936346-1|CAI43226.1| 2607|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2607
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1257
>BX664723-3|CAI43197.1| 2647|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2647
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1257
>BX664723-2|CAI43199.1| 2639|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2639
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1257
>BX664723-1|CAI43198.1| 2607|Homo sapiens filamin A, alpha (actin
binding protein 280) protein.
Length = 2607
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1200 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1257
>AK090427-1|BAC03408.1| 2651|Homo sapiens FLJ00343 protein protein.
Length = 2651
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1212 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1269
>AK074048-1|BAB84874.1| 1455|Homo sapiens FLJ00119 protein protein.
Length = 1455
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 16 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 73
>AB191260-1|BAD52436.1| 2620|Homo sapiens filamin A protein.
Length = 2620
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1173 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1230
>AB191259-1|BAD52435.1| 2612|Homo sapiens filamin A protein.
Length = 2612
Score = 31.5 bits (68), Expect = 4.3
Identities = 18/58 (31%), Positives = 27/58 (46%)
Frame = -2
Query: 339 EKGSKGQLGLNDLTGGTFTISNIGIVGGTYTKPVIFPPQVAIGALGKIQVLPRFDSQG 166
E G ++ + D GT TI+ I + G YT + + Q K+QV P D+ G
Sbjct: 1173 EAGLPAEVYIQDHGDGTHTITYIPLCPGAYTVTIKYGGQPVPNFPSKLQVEPAVDTSG 1230
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 124,008,418
Number of Sequences: 237096
Number of extensions: 2637891
Number of successful extensions: 5136
Number of sequences better than 10.0: 39
Number of HSP's better than 10.0 without gapping: 4750
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5105
length of database: 76,859,062
effective HSP length: 90
effective length of database: 55,520,422
effective search space used: 11548247776
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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