Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV19d08f
(671 letters)
Database: uniref50
1,657,284 sequences; 575,637,011 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide ... 161 2e-38
UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA ... 155 7e-37
UniRef50_Q5VVL7 Cluster: Dihydrolipoamide branched chain transac... 145 7e-34
UniRef50_P11182 Cluster: Lipoamide acyltransferase component of ... 145 7e-34
UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide ... 141 2e-32
UniRef50_UPI000155CECB Cluster: PREDICTED: similar to transacyla... 140 4e-32
UniRef50_UPI0000E48C7F Cluster: PREDICTED: similar to transacyla... 136 3e-31
UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila melanog... 123 5e-27
UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of ... 118 1e-25
UniRef50_A4RMY6 Cluster: Putative uncharacterized protein; n=1; ... 117 3e-25
UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1; ... 112 8e-24
UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain transac... 109 6e-23
UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1; Dictyo... 107 2e-22
UniRef50_UPI0001555D03 Cluster: PREDICTED: similar to 2-oxogluta... 107 2e-22
UniRef50_Q7SH25 Cluster: Putative uncharacterized protein NCU027... 107 2e-22
UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain transac... 105 1e-21
UniRef50_Q4P9L5 Cluster: Putative uncharacterized protein; n=1; ... 101 2e-20
UniRef50_Q4U9K9 Cluster: 2-oxoglutarate dehydrogenase complex su... 100 3e-20
UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2; ... 98 2e-19
UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid dehydrog... 97 3e-19
UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, wh... 97 3e-19
UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2 comp... 91 2e-17
UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9; Eur... 91 2e-17
UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex,... 88 2e-16
UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8; Plas... 83 6e-15
UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 81 2e-14
UniRef50_Q5KP05 Cluster: Tricarboxylic acid cycle-related protei... 80 4e-14
UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 / dihydrolipo... 80 4e-14
UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep: ... 79 1e-13
UniRef50_A1RJV4 Cluster: Catalytic domain of components of vario... 77 3e-13
UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransfera... 77 3e-13
UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2 compo... 77 5e-13
UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 76 9e-13
UniRef50_A4BTC4 Cluster: Dihydrolipoamide acetyltransferase; n=2... 75 1e-12
UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E... 74 3e-12
UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase, p... 74 3e-12
UniRef50_A6TMP1 Cluster: Catalytic domain of components of vario... 73 5e-12
UniRef50_Q5ZV80 Cluster: Dihydrolipoamide acetyltransferase; n=5... 73 6e-12
UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3; Cystoba... 73 6e-12
UniRef50_A4WK39 Cluster: Catalytic domain of components of vario... 72 1e-11
UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2, dihy... 72 1e-11
UniRef50_A6PJ30 Cluster: Catalytic domain of components of vario... 70 4e-11
UniRef50_P37942 Cluster: Lipoamide acyltransferase component of ... 70 4e-11
UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase co... 69 1e-10
UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n... 69 1e-10
UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase comp... 69 1e-10
UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase co... 69 1e-10
UniRef50_Q83DQ8 Cluster: Dehydrogenase, E2 component, acyltransf... 68 2e-10
UniRef50_A6FIQ1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 68 2e-10
UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2... 68 2e-10
UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 68 2e-10
UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, ... 67 3e-10
UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase comp... 67 3e-10
UniRef50_UPI00006D8691 Cluster: COG0508: Pyruvate/2-oxoglutarate... 67 4e-10
UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3; ... 67 4e-10
UniRef50_P09062 Cluster: Lipoamide acyltransferase component of ... 67 4e-10
UniRef50_A0JUQ7 Cluster: Catalytic domain of components of vario... 66 6e-10
UniRef50_Q7D716 Cluster: 2-oxoisovalerate dehydrogenase E2 compo... 66 7e-10
UniRef50_Q1GTH9 Cluster: Catalytic domain of components of vario... 66 7e-10
UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;... 66 7e-10
UniRef50_Q15U82 Cluster: Catalytic domain of components of vario... 66 1e-09
UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue acetyltrans... 66 1e-09
UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4; Bacilla... 65 1e-09
UniRef50_A0K281 Cluster: Catalytic domain of components of vario... 65 1e-09
UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2... 65 2e-09
UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1; Pyrobac... 65 2e-09
UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of ... 65 2e-09
UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2; Actinom... 64 2e-09
UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of p... 64 3e-09
UniRef50_A5UTW4 Cluster: Catalytic domain of components of vario... 64 4e-09
UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1; Bdellov... 63 7e-09
UniRef50_A6PBA2 Cluster: Catalytic domain of components of vario... 62 9e-09
UniRef50_A0LQU7 Cluster: Catalytic domain of components of vario... 62 9e-09
UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8; My... 62 1e-08
UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n... 61 2e-08
UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue acetyltrans... 61 2e-08
UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of ... 61 3e-08
UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 61 3e-08
UniRef50_A3JES0 Cluster: 2-oxoglutarate dehydrogenase E2; n=1; M... 60 4e-08
UniRef50_A0XBY6 Cluster: Biotin/lipoyl attachment domain-contain... 60 4e-08
UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid... 60 5e-08
UniRef50_A6UDY3 Cluster: Biotin/lipoyl attachment domain-contain... 60 5e-08
UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue ac... 60 6e-08
UniRef50_A0JY25 Cluster: Biotin/lipoyl attachment domain-contain... 59 8e-08
UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3 compo... 59 1e-07
UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 59 1e-07
UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue succinyltra... 59 1e-07
UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1... 58 1e-07
UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic doma... 58 1e-07
UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2 com... 58 2e-07
UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1; Symbiob... 58 2e-07
UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid dehydrog... 58 2e-07
UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1... 58 2e-07
UniRef50_A0JZU9 Cluster: Catalytic domain of components of vario... 58 2e-07
UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue acetyltrans... 58 2e-07
UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase co... 58 3e-07
UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue succinyltra... 58 3e-07
UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.... 57 3e-07
UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue succinyltra... 57 3e-07
UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue succinyltra... 57 3e-07
UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=... 57 4e-07
UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue succinyltra... 56 6e-07
UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex dihydrol... 56 8e-07
UniRef50_A0JS87 Cluster: Catalytic domain of components of vario... 56 8e-07
UniRef50_Q97Y20 Cluster: Dihydrolipoamide S-acetyltransferase, a... 56 8e-07
UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue acetyltrans... 56 8e-07
UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase comp... 55 1e-06
UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep... 55 2e-06
UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;... 55 2e-06
UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue acetyltrans... 55 2e-06
UniRef50_UPI00005103B2 Cluster: COG0508: Pyruvate/2-oxoglutarate... 54 2e-06
UniRef50_UPI000038E473 Cluster: hypothetical protein Faci_030003... 54 2e-06
UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E... 54 3e-06
UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue succinyltra... 54 3e-06
UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic doma... 54 4e-06
UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 54 4e-06
UniRef50_Q89AQ9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 54 4e-06
UniRef50_A0G738 Cluster: Catalytic domain of components of vario... 53 5e-06
UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n... 53 7e-06
UniRef50_Q8PQ85 Cluster: Dihydrolipoamide acyltransferase; n=7; ... 53 7e-06
UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n... 53 7e-06
UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue acetyltrans... 53 7e-06
UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 53 7e-06
UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransfera... 52 1e-05
UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component, d... 52 1e-05
UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X compon... 52 1e-05
UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4; Actinomycet... 52 1e-05
UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;... 52 1e-05
UniRef50_A1SJ23 Cluster: Catalytic domain of components of vario... 46 1e-05
UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 52 2e-05
UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue acetyltrans... 52 2e-05
UniRef50_A0LLM2 Cluster: Catalytic domain of components of vario... 52 2e-05
UniRef50_Q7NLM9 Cluster: Gll1092 protein; n=1; Gloeobacter viola... 51 2e-05
UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid dehydrog... 51 2e-05
UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;... 51 2e-05
UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 51 2e-05
UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue succinyltra... 51 2e-05
UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of ... 51 2e-05
UniRef50_A1UIB1 Cluster: Catalytic domain of components of vario... 51 2e-05
UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 51 3e-05
UniRef50_Q7N5R0 Cluster: Similarities with dihydrolipoamide acyl... 51 3e-05
UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1; ... 50 4e-05
UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 50 4e-05
UniRef50_Q6KH64 Cluster: Pyruvate dehydrogenase E3 component dih... 50 5e-05
UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme comp... 50 5e-05
UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue acetyltrans... 50 5e-05
UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 50 5e-05
UniRef50_Q5BXT9 Cluster: SJCHGC06137 protein; n=1; Schistosoma j... 50 5e-05
UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue succinyltra... 50 5e-05
UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase co... 50 7e-05
UniRef50_Q7X2B2 Cluster: PdhC; n=1; Lactobacillus reuteri|Rep: P... 50 7e-05
UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2 comp... 50 7e-05
UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;... 50 7e-05
UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella ve... 50 7e-05
UniRef50_Q2UDD6 Cluster: Predicted protein; n=1; Aspergillus ory... 50 7e-05
UniRef50_O94709 Cluster: Probable pyruvate dehydrogenase protein... 50 7e-05
UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue acetyltrans... 50 7e-05
UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex d... 49 9e-05
UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferas... 49 9e-05
UniRef50_Q4AFR6 Cluster: Biotin/lipoyl attachment; n=1; Chlorobi... 49 9e-05
UniRef50_A6Q9K5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 49 9e-05
UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue succinyltra... 49 9e-05
UniRef50_Q4QCG0 Cluster: Dihydrolipoamide acetyltransferaselike ... 49 9e-05
UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1; ... 49 9e-05
UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n... 49 1e-04
UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 compone... 49 1e-04
UniRef50_A1SQB9 Cluster: Catalytic domain of components of vario... 49 1e-04
UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 49 1e-04
UniRef50_Q6CF67 Cluster: Yarrowia lipolytica chromosome B of str... 49 1e-04
UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to ENSANGP000... 48 2e-04
UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of ... 48 2e-04
UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue succinyltra... 48 2e-04
UniRef50_A1UBW5 Cluster: Catalytic domain of components of vario... 48 2e-04
UniRef50_A1FTV4 Cluster: Catalytic domain of components of vario... 48 2e-04
UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillu... 48 2e-04
UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1; ... 48 2e-04
UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep: M... 48 3e-04
UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component dih... 48 3e-04
UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=... 48 3e-04
UniRef50_Q59RQ7 Cluster: Putative uncharacterized protein; n=1; ... 48 3e-04
UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;... 47 4e-04
UniRef50_A6W003 Cluster: Catalytic domain of components of vario... 47 4e-04
UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1; ... 47 4e-04
UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).; ... 47 5e-04
UniRef50_Q8D6Q5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 47 5e-04
UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases acyl... 47 5e-04
UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n... 47 5e-04
UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of ... 47 5e-04
UniRef50_Q38C09 Cluster: Dihydrolipoamide acetyltransferase, put... 47 5e-04
UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;... 46 6e-04
UniRef50_A6X6G3 Cluster: Biotin/lipoyl attachment domain protein... 46 6e-04
UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 46 6e-04
UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 46 6e-04
UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 46 6e-04
UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue succinyltra... 46 6e-04
UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1; Streptom... 46 8e-04
UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase... 46 8e-04
UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1... 46 8e-04
UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;... 46 8e-04
UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue acetyltrans... 46 8e-04
UniRef50_Q7CNS6 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMP... 46 0.001
UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 45 0.001
UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7; ro... 45 0.001
UniRef50_A5V538 Cluster: Catalytic domain of components of vario... 45 0.001
UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subuni... 45 0.001
UniRef50_Q7RWS2 Cluster: Putative uncharacterized protein NCU000... 45 0.001
UniRef50_Q830B2 Cluster: Acetyl-CoA carboxylase, biotin carboxyl... 45 0.002
UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 45 0.002
UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2 compo... 45 0.002
UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2; ... 45 0.002
UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue acetyltrans... 45 0.002
UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase c... 44 0.003
UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase comp... 44 0.003
UniRef50_Q4AFC2 Cluster: Biotin/lipoyl attachment; n=1; Chlorobi... 44 0.003
UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, lon... 44 0.003
UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 44 0.003
UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase homo... 44 0.003
UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 44 0.003
UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n... 44 0.003
UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransfera... 44 0.003
UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex dihydrol... 44 0.003
UniRef50_Q9SXV7 Cluster: Dihydrolipoamide acetyltransferase; n=1... 44 0.003
UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue succinyltra... 44 0.003
UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue succinyltra... 44 0.003
UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase; ... 44 0.004
UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransfer... 44 0.004
UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransfera... 44 0.004
UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue succinyltra... 44 0.004
UniRef50_A0LSF1 Cluster: Catalytic domain of components of vario... 44 0.004
UniRef50_Q9SQI8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 44 0.004
UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit... 44 0.004
UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component sub... 44 0.004
UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate d... 43 0.006
UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,... 43 0.006
UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic doma... 43 0.006
UniRef50_A6Q3I4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 43 0.006
UniRef50_A5ZAG1 Cluster: Putative uncharacterized protein; n=1; ... 43 0.006
UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC - Clos... 43 0.006
UniRef50_Q4DYI5 Cluster: Dihydrolipoamide acetyltransferase, put... 43 0.006
UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 43 0.006
UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome s... 43 0.008
UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2; Geobaci... 43 0.008
UniRef50_Q59658 Cluster: Dihydrolipoamide acetyltransferase; n=3... 43 0.008
UniRef50_A1W7R7 Cluster: Dihydrolipoamide dehydrogenase; n=58; B... 43 0.008
UniRef50_Q6CNU8 Cluster: Kluyveromyces lactis strain NRRL Y-1140... 43 0.008
UniRef50_A1WK19 Cluster: Alpha/beta hydrolase fold; n=1; Vermine... 35 0.009
UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex, dihydro... 42 0.010
UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2 comp... 42 0.010
UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1... 42 0.010
UniRef50_Q0A5F2 Cluster: Catalytic domain of components of vario... 42 0.010
UniRef50_UPI00015A4520 Cluster: UPI00015A4520 related cluster; n... 42 0.014
UniRef50_Q39ET0 Cluster: Dihydrolipoamide acetyltransferase; n=4... 42 0.014
UniRef50_Q2J8A0 Cluster: Dehydrogenase subunit; n=9; Actinobacte... 42 0.014
UniRef50_A5V4B2 Cluster: Catalytic domain of components of vario... 42 0.014
UniRef50_Q74Z83 Cluster: AGR323Cp; n=1; Eremothecium gossypii|Re... 42 0.014
UniRef50_Q6FDE9 Cluster: Dihydrolipoamide acetyltransferase; n=3... 42 0.018
UniRef50_Q5P9T5 Cluster: Dihydrolipoamide acetyltransferase comp... 42 0.018
UniRef50_A4SZ52 Cluster: Catalytic domain of components of vario... 42 0.018
UniRef50_A4L2T6 Cluster: AccB; n=2; Lactobacillus reuteri|Rep: A... 42 0.018
UniRef50_A4FIZ9 Cluster: Acetoin dehydrogenase, dihydrolipoamide... 42 0.018
UniRef50_Q4WQ92 Cluster: 2-oxo acid dehydrogenases acyltransfera... 42 0.018
UniRef50_Q8RD59 Cluster: Dihydrolipoamide acyltransferases; n=1;... 41 0.024
UniRef50_A0G901 Cluster: Biotin/lipoyl attachment; n=1; Burkhold... 41 0.024
UniRef50_A2WZU5 Cluster: Putative uncharacterized protein; n=2; ... 41 0.024
UniRef50_A0CWR1 Cluster: Chromosome undetermined scaffold_3, who... 41 0.024
UniRef50_P36957 Cluster: Dihydrolipoyllysine-residue succinyltra... 41 0.024
UniRef50_UPI00015552BA Cluster: PREDICTED: similar to dihydrolip... 41 0.031
UniRef50_UPI0000DB7177 Cluster: PREDICTED: similar to Pyruvate d... 41 0.031
UniRef50_Q1AT73 Cluster: Catalytic domain of components of vario... 41 0.031
UniRef50_A0NRH6 Cluster: 2-oxo acid dehydrogenases acyltransfera... 41 0.031
UniRef50_Q4Q1F5 Cluster: Dihydrolipoamide acetyltransferase, put... 41 0.031
UniRef50_P45118 Cluster: Dihydrolipoyllysine-residue acetyltrans... 41 0.031
UniRef50_Q057U1 Cluster: Pyruvate dehydrogenase E2 component; n=... 40 0.041
UniRef50_A6GQ97 Cluster: Dihydrolipoamide acetyltransferase (E2)... 40 0.041
UniRef50_A3VIE9 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 40 0.041
UniRef50_A3U7C0 Cluster: Lipoamide acyltransferase component of ... 40 0.041
UniRef50_Q5BY55 Cluster: SJCHGC04170 protein; n=1; Schistosoma j... 40 0.041
UniRef50_A7AMV7 Cluster: Biotin-requiring enzyme family protein;... 40 0.041
UniRef50_Q12FH2 Cluster: Catalytic domain of components of vario... 40 0.055
UniRef50_P36413 Cluster: Dihydrolipoyllysine-residue acetyltrans... 40 0.055
UniRef50_Q6FYD4 Cluster: Dihydrolipoyllysine-residue succinyltra... 40 0.055
UniRef50_Q1YS54 Cluster: Dihydrolipoamide acetyltransferase; n=1... 40 0.072
UniRef50_Q1V1J3 Cluster: Dihydrolipoamide S-acetyltransferase; n... 40 0.072
UniRef50_A1SN86 Cluster: Biotin/lipoyl attachment domain-contain... 40 0.072
UniRef50_A1R7P9 Cluster: Biotin / lipoyl attachment domain prote... 40 0.072
UniRef50_A7TK36 Cluster: Putative uncharacterized protein; n=1; ... 40 0.072
UniRef50_Q7NHG8 Cluster: Dihydrolipoamide S-acetyltransferase; n... 39 0.096
UniRef50_A1SQ65 Cluster: Catalytic domain of components of vario... 39 0.096
UniRef50_P16451 Cluster: Pyruvate dehydrogenase complex protein ... 39 0.096
UniRef50_Q5FS04 Cluster: Dihydrolipoamide succinyl transferase (... 39 0.13
UniRef50_Q0SJA7 Cluster: Dihydrolipoyllysine-residue succinyltra... 39 0.13
UniRef50_A2VX19 Cluster: Pyruvate dehydrogenase complex, dehydro... 39 0.13
UniRef50_A0H458 Cluster: 2-oxoglutarate dehydrogenase, E2 compon... 39 0.13
UniRef50_P10515 Cluster: Dihydrolipoyllysine-residue acetyltrans... 39 0.13
UniRef50_Q9RYB8 Cluster: 2-oxo acid dehydrogenase, E2 component;... 38 0.17
UniRef50_Q3SL16 Cluster: Pyruvate/2-oxoglutarate dehydrogenase c... 38 0.17
UniRef50_P96104 Cluster: Dihydrolipoyl transacetylase and lipoam... 38 0.17
UniRef50_O59816 Cluster: Dihydrolipoyllysine-residue acetyltrans... 38 0.17
UniRef50_Q59695 Cluster: Dihydrolipoyllysine-residue acetyltrans... 38 0.17
UniRef50_Q6N5V4 Cluster: Pyruvate dehydrogenase E1 beta subunit;... 38 0.22
UniRef50_Q1VYW1 Cluster: Dihydrolipoyllysine-residue acetyltrans... 38 0.22
UniRef50_A0YCP9 Cluster: Pyruvate dehydrogenase complex dihydrol... 38 0.22
UniRef50_Q8D2N2 Cluster: AceF protein; n=1; Wigglesworthia gloss... 38 0.29
UniRef50_Q5HKM0 Cluster: Acetoin dehydrogenase, E2 component, di... 38 0.29
UniRef50_Q7BKG0 Cluster: Predicted biotin carboxyl carrier prote... 38 0.29
UniRef50_Q1M9D5 Cluster: Putative biotin-binding protein; n=1; R... 38 0.29
UniRef50_Q8EJN8 Cluster: Pyruvate dehydrogenase complex, E2 comp... 37 0.39
UniRef50_Q53594 Cluster: E2 branched-chain alpha keto acid dehyd... 37 0.39
UniRef50_A4XEQ9 Cluster: Catalytic domain of components of vario... 37 0.39
UniRef50_A3UCP2 Cluster: Dihydrolipoamide acetyltransferase; n=1... 37 0.39
UniRef50_Q7RFX9 Cluster: Putative dihydrolipoamide S-acetyltrans... 37 0.39
UniRef50_Q4PHZ8 Cluster: Putative uncharacterized protein; n=1; ... 37 0.39
UniRef50_Q92HK7 Cluster: Dihydrolipoyllysine-residue acetyltrans... 37 0.39
UniRef50_A6GG26 Cluster: Dihydrolipoyllysine-residue acetyltrans... 37 0.51
UniRef50_A3CMZ5 Cluster: Dihydrolipoamide acetyl transferase, E2... 37 0.51
UniRef50_Q6PLQ2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 37 0.51
UniRef50_Q8U4T3 Cluster: 2-oxo acid dehydrogenase lipoyl domain;... 37 0.51
UniRef50_Q9R9N3 Cluster: Dihydrolipoyllysine-residue acetyltrans... 37 0.51
UniRef50_Q4EDM9 Cluster: Putative uncharacterized protein; n=1; ... 36 0.67
UniRef50_Q04DN3 Cluster: Biotin carboxyl carrier protein; n=1; O... 36 0.67
UniRef50_A4RM31 Cluster: Putative uncharacterized protein; n=1; ... 36 0.67
UniRef50_A6DTS5 Cluster: Pyruvate dehydrogenase complex , E2 com... 36 0.89
UniRef50_A4F1Y4 Cluster: Dihydrolopoamide acyltransferase; n=1; ... 36 0.89
UniRef50_Q899N8 Cluster: Biotin carboxyl carrier protein of acet... 36 1.2
UniRef50_Q5NZW1 Cluster: Biotin carboxyl carrier subunit of acet... 36 1.2
UniRef50_Q39FN4 Cluster: Alpha/beta hydrolase; n=10; Burkholderi... 36 1.2
UniRef50_Q1IUH9 Cluster: Carbamoyl-phosphate synthase L chain, A... 36 1.2
UniRef50_Q5VGY2 Cluster: Dihydrolipoamide S-acetyltransferase; n... 36 1.2
UniRef50_A5KCF0 Cluster: Dihydrolipoamide acetyltransferase, put... 36 1.2
UniRef50_O66119 Cluster: Dihydrolipoyllysine-residue acetyltrans... 36 1.2
UniRef50_O94681 Cluster: Probable dihydrolipoyllysine-residue su... 36 1.2
UniRef50_A6S7Q2 Cluster: Predicted protein; n=2; Sclerotiniaceae... 28 1.5
UniRef50_UPI00006DB259 Cluster: COG0508: Pyruvate/2-oxoglutarate... 35 1.6
UniRef50_Q8F3R1 Cluster: Biotin_lipoyl domain protein; n=4; Lept... 35 1.6
UniRef50_Q2S152 Cluster: Dihydrolipoyllysine-residue acetyltrans... 35 1.6
UniRef50_Q10B57 Cluster: Retrotransposon protein, putative, uncl... 35 1.6
UniRef50_A7Q7E8 Cluster: Chromosome chr18 scaffold_59, whole gen... 35 1.6
UniRef50_Q83C43 Cluster: Conserved domain protein; n=2; Coxiella... 35 2.1
UniRef50_A4XHV3 Cluster: Catalytic domain of components of vario... 35 2.1
UniRef50_A1AXV6 Cluster: Acetyl-CoA carboxylase, biotin carboxyl... 35 2.1
UniRef50_Q96RQ3 Cluster: Methylcrotonoyl-CoA carboxylase subunit... 35 2.1
UniRef50_Q7VDH5 Cluster: Dihydrolipoamide S-acetyltransferase; n... 34 2.7
UniRef50_Q187Q0 Cluster: Biotin carboxyl carrier protein of acet... 34 2.7
UniRef50_Q6ZBH9 Cluster: Probable protein NAP1; n=6; Magnoliophy... 34 2.7
UniRef50_Q1PVI6 Cluster: Putative uncharacterized protein; n=1; ... 34 3.6
UniRef50_O66382 Cluster: Esterase2; n=2; Acetobacteraceae|Rep: E... 34 3.6
UniRef50_Q5KEE0 Cluster: Pyruvate dehydrogenase protein x compon... 34 3.6
UniRef50_UPI0000509C9C Cluster: hypothetical protein LOC549074; ... 33 4.8
UniRef50_Q8F4N2 Cluster: Dihydrolipoamide acetyltransferase comp... 33 4.8
UniRef50_A6LSC7 Cluster: Acetyl-CoA carboxylase, biotin carboxyl... 33 4.8
UniRef50_Q5DAY9 Cluster: SJCHGC06539 protein; n=1; Schistosoma j... 33 4.8
UniRef50_P29539 Cluster: Protein RIF1; n=2; Saccharomyces cerevi... 33 4.8
UniRef50_UPI00006CB9E3 Cluster: hypothetical protein TTHERM_0055... 33 6.3
UniRef50_Q8FLT6 Cluster: Putative 2-hydroxycyclohexanecarboxyl-C... 33 6.3
UniRef50_Q74AE1 Cluster: Dehydrogenase complex E2 component, dih... 33 6.3
UniRef50_Q30UQ0 Cluster: Ste24 endopeptidase precursor; n=1; Des... 33 6.3
UniRef50_O84249 Cluster: Dihydrolipoamide Acetyltransferase; n=7... 33 6.3
UniRef50_Q1GJN0 Cluster: Formate dehydrogenase gamma subunit; n=... 33 6.3
UniRef50_Q12PC7 Cluster: Secretion protein HlyD precursor; n=1; ... 33 6.3
UniRef50_A7GYF7 Cluster: MacA; n=3; Campylobacter|Rep: MacA - Ca... 33 6.3
UniRef50_A6UGY8 Cluster: Dihydrolipoyllysine-residue succinyltra... 33 6.3
UniRef50_A6TX89 Cluster: Efflux transporter, RND family, MFP sub... 33 6.3
UniRef50_A6GLP0 Cluster: Probable acyl-coa carboxylase alpha cha... 33 6.3
UniRef50_A5I7X2 Cluster: Biotin carboxyl carrier protein of acet... 33 6.3
UniRef50_A3J4H8 Cluster: Putative uncharacterized protein; n=1; ... 33 6.3
UniRef50_A4RXN8 Cluster: Predicted protein; n=3; cellular organi... 33 6.3
UniRef50_P20285 Cluster: Dihydrolipoyllysine-residue acetyltrans... 33 6.3
UniRef50_Q1WUR9 Cluster: Biotin carboxyl carrier protein of acet... 33 8.3
UniRef50_Q1Q3X0 Cluster: Putative uncharacterized protein; n=1; ... 33 8.3
UniRef50_Q1EYD1 Cluster: Acetyl-CoA biotin carboxyl carrier; n=1... 33 8.3
UniRef50_Q15Y91 Cluster: Efflux transporter, RND family, MFP sub... 33 8.3
UniRef50_Q13GQ6 Cluster: Dihydrolipoamide acyltransferase (E2) c... 33 8.3
UniRef50_A6BCV2 Cluster: Putative uncharacterized protein; n=2; ... 33 8.3
UniRef50_A4M1P4 Cluster: Biotin/lipoyl attachment domain-contain... 33 8.3
UniRef50_Q0E0X4 Cluster: Os02g0514700 protein; n=2; Oryza sativa... 33 8.3
UniRef50_A3CFJ5 Cluster: Putative uncharacterized protein; n=2; ... 33 8.3
UniRef50_Q9P6U5 Cluster: Related to protease ULP2 protein; n=1; ... 33 8.3
>UniRef50_UPI0000D56122 Cluster: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ...; n=1; Tribolium
castaneum|Rep: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ... - Tribolium
castaneum
Length = 429
Score = 161 bits (390), Expect = 2e-38
Identities = 81/150 (54%), Positives = 105/150 (70%), Gaps = 2/150 (1%)
Frame = +1
Query: 226 LRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 405
L++FH+ + V+FKLSDIGEGIREV +KEWFVKVGD V QFD ICEVQSDKA+VTIT
Sbjct: 23 LKNFHSCASYAAQVSFKLSDIGEGIREVTVKEWFVKVGDKVSQFDEICEVQSDKASVTIT 82
Query: 406 SRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDK-PVAEID-APKTEQN 579
SRYDG+I +L++ ID+ A VG+PLVDI+ + E PT K PV EI + T+
Sbjct: 83 SRYDGVIKKLHYKIDEIASVGKPLVDIETEGDEPSAAPTPEEESKPPVEEIKISEPTDPQ 142
Query: 580 QKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
++L P+VRR+A + KV+L V TG+
Sbjct: 143 PTAEILCIPSVRRLAKEHKVNLWEVTGTGK 172
>UniRef50_Q9VXY3 Cluster: CG5599-PA; n=4; Diptera|Rep: CG5599-PA -
Drosophila melanogaster (Fruit fly)
Length = 462
Score = 155 bits (377), Expect = 7e-37
Identities = 78/160 (48%), Positives = 109/160 (68%), Gaps = 13/160 (8%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
R H + +++K V+F LSDIGEGIREV +KEWFVK GD V+QFDN+CEVQSDKA+VTITS
Sbjct: 27 RCLHVTSSLDKTVSFNLSDIGEGIREVTVKEWFVKEGDTVEQFDNLCEVQSDKASVTITS 86
Query: 409 RYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQK- 585
RYDG IT+++H ID+ ALVG+PL+D DV + + D +P D + D+ +E +K
Sbjct: 87 RYDGKITKIHHKIDEIALVGKPLLDFDVVNEDED-EPEDSSSSSSSTSSDSSASENEEKQ 145
Query: 586 ------------IKVLTTPAVRRIAAQFKVDLSAVKATGR 669
+ + TP+VRR+A + ++DL+ V ATG+
Sbjct: 146 SAEASATPTEGRVIIPATPSVRRLAKEHQLDLAKVPATGK 185
>UniRef50_Q5VVL7 Cluster: Dihydrolipoamide branched chain
transacylase E2; n=8; Euteleostomi|Rep: Dihydrolipoamide
branched chain transacylase E2 - Homo sapiens (Human)
Length = 320
Score = 145 bits (352), Expect = 7e-34
Identities = 74/140 (52%), Positives = 98/140 (70%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 63 QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 122
Query: 439 HDIDQTALVGQPLVDID---VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
+++D A VG+PLVDI+ ++DSE D + P D ++ + K L TPA
Sbjct: 123 YNLDDIAYVGKPLVDIETEALKDSEED------VVETPAVSHDEHTHQEIKGRKTLATPA 176
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + + LS V +G+
Sbjct: 177 VRRLAMENNIKLSEVVGSGK 196
>UniRef50_P11182 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex,
mitochondrial precursor (EC 2.3.1.168)
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase); n=29; Eumetazoa|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex, mitochondrial
precursor (EC 2.3.1.168) (Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) - Homo sapiens (Human)
Length = 482
Score = 145 bits (352), Expect = 7e-34
Identities = 74/140 (52%), Positives = 98/140 (70%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 63 QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 122
Query: 439 HDIDQTALVGQPLVDID---VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
+++D A VG+PLVDI+ ++DSE D + P D ++ + K L TPA
Sbjct: 123 YNLDDIAYVGKPLVDIETEALKDSEED------VVETPAVSHDEHTHQEIKGRKTLATPA 176
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + + LS V +G+
Sbjct: 177 VRRLAMENNIKLSEVVGSGK 196
>UniRef50_UPI0000DB75B7 Cluster: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ...; n=2;
Apocrita|Rep: PREDICTED: similar to Lipoamide
acyltransferase component of branched-chain alpha-keto
acid dehydrogenase complex, mitochondrial precursor
(Dihydrolipoyllysine-residue
(2-methylpropanoyl)transferase) (E2) (Dihydrolipoamide
branched chain transacylase) (BCKAD ... - Apis mellifera
Length = 501
Score = 141 bits (341), Expect = 2e-32
Identities = 73/151 (48%), Positives = 98/151 (64%), Gaps = 1/151 (0%)
Frame = +1
Query: 220 KELRHFHTSH-AVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAV 396
++ R F S+ +V FKLSDIGEGIR+V IKEW+VK GD V QFDNICEVQSDKA+V
Sbjct: 92 QKCRFFSVSYFRYGTVVPFKLSDIGEGIRDVTIKEWYVKPGDRVSQFDNICEVQSDKASV 151
Query: 397 TITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQ 576
TITSRYDG+I L++ +D L+G L+DI++ D + + T K E E+
Sbjct: 152 TITSRYDGLIKALHYKVDDIVLIGNSLLDIELDDDKQQQQQTTNTKSKQNFE---SNEEK 208
Query: 577 NQKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
+ K+L TPAVRRIA + ++L V + G+
Sbjct: 209 HIVKKILATPAVRRIAMEKNINLKDVVSNGK 239
>UniRef50_UPI000155CECB Cluster: PREDICTED: similar to transacylase;
n=1; Ornithorhynchus anatinus|Rep: PREDICTED: similar to
transacylase - Ornithorhynchus anatinus
Length = 325
Score = 140 bits (338), Expect = 4e-32
Identities = 75/148 (50%), Positives = 102/148 (68%), Gaps = 1/148 (0%)
Frame = +1
Query: 214 LSKELRHFHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKA 390
LS R T+ AV+ +IV FKLSDIGEGI EV +KEW+VK GD V QFD+ICEVQSDKA
Sbjct: 177 LSLPRRLLRTTAAVDGQIVQFKLSDIGEGITEVTVKEWYVKEGDTVSQFDSICEVQSDKA 236
Query: 391 AVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKT 570
+VTITSRYDGII +L++++++TA VG+PLVDI+ + + DV + P +
Sbjct: 237 SVTITSRYDGIIRKLHYNVEETANVGKPLVDIETEAVK--ASEEDVV-ETPAVSHEEHTH 293
Query: 571 EQNQKIKVLTTPAVRRIAAQFKVDLSAV 654
++ + K L TPAVRR+A + V +S +
Sbjct: 294 QEIKGHKTLATPAVRRLAMENNVKISEI 321
>UniRef50_UPI0000E48C7F Cluster: PREDICTED: similar to transacylase;
n=2; Deuterostomia|Rep: PREDICTED: similar to
transacylase - Strongylocentrotus purpuratus
Length = 620
Score = 136 bits (330), Expect = 3e-31
Identities = 66/148 (44%), Positives = 99/148 (66%), Gaps = 5/148 (3%)
Frame = +1
Query: 241 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 420
+S + ++V FKLSDIGEGI EVV+KEW+V GD V QFD+ICEVQSDKA+VTITSR+DG
Sbjct: 80 SSRSCGEVVQFKLSDIGEGIMEVVVKEWYVSEGDTVAQFDSICEVQSDKASVTITSRFDG 139
Query: 421 IITRLYHDIDQTALVGQPLVDIDV-----QDSENDGKPTDVAPDKPVAEIDAPKTEQNQK 585
++ +L++++++TA VG PLVDI++ S+ + + + D + K
Sbjct: 140 VVKKLHYELEETANVGMPLVDIELAGEISTPSQEEDVSGETSSDSDSDTERGAVSTTRGK 199
Query: 586 IKVLTTPAVRRIAAQFKVDLSAVKATGR 669
+ L+TPAV+R+A + + L+ V TG+
Sbjct: 200 ARTLSTPAVKRLAMEHNISLNDVHGTGK 227
>UniRef50_Q6C806 Cluster: Similar to tr|Q9VXY3 Drosophila
melanogaster CG5599 protein; n=1; Yarrowia
lipolytica|Rep: Similar to tr|Q9VXY3 Drosophila
melanogaster CG5599 protein - Yarrowia lipolytica
(Candida lipolytica)
Length = 466
Score = 123 bits (296), Expect = 5e-27
Identities = 67/168 (39%), Positives = 94/168 (55%), Gaps = 21/168 (12%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
R H H ++ FKL+DIGEGI+E + +WFV+ G + +FD ICEVQSDKA+V ITS
Sbjct: 24 RALHACHIARAVIPFKLADIGEGIKECEVIQWFVEPGARINEFDQICEVQSDKASVEITS 83
Query: 409 RYDGIITRLYHDIDQTALVGQPLVDIDVQD-----SENDGKPTDVAPDKPVAEIDAPKTE 573
RY G+I +L++D ALVG+PLVDID + SE + +D AP A P T
Sbjct: 84 RYTGVIKKLHYDAGDMALVGKPLVDIDTGEGGEGASEVAAESSDAAPSTAAATPATPLTA 143
Query: 574 QNQKI----------------KVLTTPAVRRIAAQFKVDLSAVKATGR 669
K L TPAVRR+ + +D++++K +G+
Sbjct: 144 SASVASSTATTVSSDPSKAYQKALATPAVRRLTRELGIDIASIKGSGK 191
>UniRef50_A7AT28 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex,
mitochondrial, putative; n=1; Babesia bovis|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex, mitochondrial,
putative - Babesia bovis
Length = 417
Score = 118 bits (285), Expect = 1e-25
Identities = 64/151 (42%), Positives = 91/151 (60%), Gaps = 5/151 (3%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
RHFH S NK+ F LSDIGEGI EV + W VGD V++ + +C VQSDKAAV ITS
Sbjct: 20 RHFHRSVHRNKLTTFHLSDIGEGISEVELVRWNKNVGDEVEEMETVCTVQSDKAAVDITS 79
Query: 409 RYDGIITRLYHDIDQTALVGQPLVDIDVQ-DSENDGKPTDVA----PDKPVAEIDAPKTE 573
RY G++ +LY + + +G PL+DID + D+ +PT+ P KPVA+ +
Sbjct: 80 RYTGLVKKLYVEQGKLIKIGSPLMDIDAEDDTPAVSEPTETTKSSIPSKPVAQ----SFK 135
Query: 574 QNQKIKVLTTPAVRRIAAQFKVDLSAVKATG 666
++ V P+VR++A Q VD++ V +G
Sbjct: 136 RSHGDSVRAAPSVRQLAKQLGVDITKVVPSG 166
>UniRef50_A4RMY6 Cluster: Putative uncharacterized protein; n=1;
Magnaporthe grisea|Rep: Putative uncharacterized protein
- Magnaporthe grisea (Rice blast fungus) (Pyricularia
grisea)
Length = 523
Score = 117 bits (281), Expect = 3e-25
Identities = 74/194 (38%), Positives = 108/194 (55%), Gaps = 22/194 (11%)
Frame = +1
Query: 154 TTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVK 333
TT SAR+ Q + + + + R FH++ + + L+DIGEGI E I +WFV+
Sbjct: 29 TTVSARSRQQPTQQRQ-QQRHCRTTRGFHSTRRLLDVKPVLLADIGEGIVECEIIQWFVE 87
Query: 334 VGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQ-DSEND 510
G V++F +CEVQSDKA+V ITSR+ G++ +LY+D + A VG+P VDID+ D E +
Sbjct: 88 PGARVEEFSPLCEVQSDKASVEITSRFSGVVKKLYYDAGEMAKVGKPFVDIDITGDLEAE 147
Query: 511 GKPT---DVAPDKPVAE-------------IDAPKT-----EQNQKIKVLTTPAVRRIAA 627
+ DVAP KPV E I P + + K L TPAVR ++
Sbjct: 148 PEKVLAGDVAPAKPVEEKTTQKAVETAPDMIGTPASVGGAERKRGKCAALATPAVRHLSK 207
Query: 628 QFKVDLSAVKATGR 669
+ KVD++ + TGR
Sbjct: 208 ELKVDINEIDGTGR 221
>UniRef50_Q0UN70 Cluster: Putative uncharacterized protein; n=1;
Phaeosphaeria nodorum|Rep: Putative uncharacterized
protein - Phaeosphaeria nodorum (Septoria nodorum)
Length = 490
Score = 112 bits (269), Expect = 8e-24
Identities = 61/133 (45%), Positives = 84/133 (63%), Gaps = 3/133 (2%)
Frame = +1
Query: 205 NESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSD 384
N + + R FH S + + + L+DIGEGI E + +WFVK G V+QFD ICEVQSD
Sbjct: 30 NICIQGQRRAFHGSQRLLVVKPYLLADIGEGITECQVIQWFVKPGARVEQFDPICEVQSD 89
Query: 385 KAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQD--SENDGKPTDVAPDKPVAEID 558
KA+V ITSR+DG+I +LY++ D A VG+PLVDID+Q S D + A +K +
Sbjct: 90 KASVEITSRFDGVIKKLYYEPDDMAKVGKPLVDIDIQSEISAADEALLNGASEKEAKQDA 149
Query: 559 APKTE-QNQKIKV 594
A +T Q Q ++V
Sbjct: 150 AQQTSPQEQALEV 162
>UniRef50_Q57Z16 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=3; Trypanosoma|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Trypanosoma brucei
Length = 439
Score = 109 bits (262), Expect = 6e-23
Identities = 65/160 (40%), Positives = 90/160 (56%), Gaps = 17/160 (10%)
Frame = +1
Query: 241 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 420
T + + +KL+DIGEGI+EV + +VK GD + +F+ ICEVQSDKA V ITSRY G
Sbjct: 20 TRSRCGRTIPYKLADIGEGIKEVEVVTLYVKPGDRIGEFEKICEVQSDKATVEITSRYAG 79
Query: 421 IITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPD-----------KPVAE----- 552
+IT ++ + + A VG+P+VDI+V D++ KP+ D PVAE
Sbjct: 80 VITTVHIEAGEKAHVGEPIVDIEVNDTDETQKPSCGTVDCNVSDQFNNGGVPVAEEGDSC 139
Query: 553 -IDAPKTEQNQKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
D KVL TPAVR A V+++ VK TG+
Sbjct: 140 AADCTTEISKDFTKVLATPAVREFARSRGVNITDVKGTGK 179
>UniRef50_Q54TR7 Cluster: Dihydrolipoyl transacylase; n=1;
Dictyostelium discoideum AX4|Rep: Dihydrolipoyl
transacylase - Dictyostelium discoideum AX4
Length = 517
Score = 107 bits (258), Expect = 2e-22
Identities = 63/161 (39%), Positives = 88/161 (54%), Gaps = 26/161 (16%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
+ F L+D+GEGI E + W+VK GD +++FD +CEVQSDKA V ITSRYDGI+T++ H
Sbjct: 78 IKFNLADVGEGIAECEVLVWYVKEGDQIKEFDKLCEVQSDKATVEITSRYDGIVTKICHK 137
Query: 445 IDQTALVGQPLVDIDVQDS-----ENDGKPTDVAPDKPVAEIDAPK-------------- 567
I A VG+PLV+I + S N G + V P + +
Sbjct: 138 IGDMAKVGEPLVEITPESSIAEIKLNAGPASQVTVTPPSVSVSSSSSVSSSVSSSVASSL 197
Query: 568 ------TEQN-QKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
T++N QK KV+ TPAVR + VDL ++ TG+
Sbjct: 198 DHEYDITKKNGQKYKVMATPAVRNLGKLKSVDLKQIQGTGK 238
>UniRef50_UPI0001555D03 Cluster: PREDICTED: similar to
2-oxoglutarate dehydrogenase complex subunit, putative,
partial; n=1; Ornithorhynchus anatinus|Rep: PREDICTED:
similar to 2-oxoglutarate dehydrogenase complex subunit,
putative, partial - Ornithorhynchus anatinus
Length = 163
Score = 107 bits (257), Expect = 2e-22
Identities = 59/147 (40%), Positives = 85/147 (57%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
R FH S I FKL DIGEGI EV + +W ++GDNV++ D +C VQSDKAAV I+S
Sbjct: 21 RSFHHSAPRQAITTFKLCDIGEGISEVELIKWEKRIGDNVEEMDAVCTVQSDKAAVEISS 80
Query: 409 RYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKI 588
RY GI+ +L+ D+ VG PL+DI+V+D E+D K N +
Sbjct: 81 RYTGIVKKLHVDVGGFIKVGAPLMDIEVEDDEDDAK--------------------NVQA 120
Query: 589 KVLTTPAVRRIAAQFKVDLSAVKATGR 669
+ +PAV++ A VD++ + A+G+
Sbjct: 121 HIKASPAVKKFARDLGVDINNIPASGK 147
>UniRef50_Q7SH25 Cluster: Putative uncharacterized protein
NCU02704.1; n=2; Sordariales|Rep: Putative
uncharacterized protein NCU02704.1 - Neurospora crassa
Length = 562
Score = 107 bits (257), Expect = 2e-22
Identities = 60/177 (33%), Positives = 94/177 (53%), Gaps = 1/177 (0%)
Frame = +1
Query: 85 MSILVRRSVFQLR-TVNRCRKIKVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNK 261
+S L RR + ++ T R T+ R S + L + L R FH + +
Sbjct: 18 VSRLSRRGLSRVAPTATSTRTPSTTSSPTRPLPGNSRSSTLAQQLPSTRRAFHATRDLKV 77
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I L+DIGEGI E + +WFV+ G V++F +CEVQSDKA+V ITSR+ G++ +LY+
Sbjct: 78 IKPVLLADIGEGIVECEVIQWFVEPGARVEEFSQLCEVQSDKASVEITSRFAGVVKKLYY 137
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAV 612
+ + A VG+P VDID++ + P PV+ ++ + + + I T AV
Sbjct: 138 EAGEMAKVGKPFVDIDIEAGPESKEVEAWTPPGPVSTLEGQQAIKGEAISTSTPQAV 194
Score = 38.3 bits (85), Expect = 0.17
Identities = 18/47 (38%), Positives = 25/47 (53%)
Frame = +1
Query: 529 APDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
A P AP T+Q K L TPAVR +A + VD++ + TG+
Sbjct: 208 ARQTPTTSSHAPVTKQTGKHASLATPAVRHLARELSVDITQIPGTGK 254
>UniRef50_Q4QJI5 Cluster: Dihydrolipoamide branched chain
transacylase, putative; n=2; Leishmania|Rep:
Dihydrolipoamide branched chain transacylase, putative -
Leishmania major
Length = 477
Score = 105 bits (252), Expect = 1e-21
Identities = 67/160 (41%), Positives = 92/160 (57%), Gaps = 13/160 (8%)
Frame = +1
Query: 229 RH-FHTSHA-VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTI 402
RH F T+ A + + + ++L+DIGEGI EV + VK GD + +FD ICEVQSDKA V I
Sbjct: 34 RHLFATTCAPLGRCIPYRLADIGEGITEVQVLGVCVKAGDTINEFDPICEVQSDKATVDI 93
Query: 403 TSRYDGIITRLYHDIDQTALVGQPLVDI------DVQDSENDGK---PTDVAPDK-PVAE 552
TSRY G++ +Y TA VG ++DI D ++ + + P APD P A
Sbjct: 94 TSRYTGVVKAVYLQPGATAKVGSVMLDIVPEGADDAPEAASPSRSAPPPSSAPDSAPQAT 153
Query: 553 IDAPKTEQNQKI-KVLTTPAVRRIAAQFKVDLSAVKATGR 669
A K + KVL TPA R +A + K+DL+ V ATG+
Sbjct: 154 YSASKPSSDASAGKVLATPATRYLAREHKLDLAHVPATGK 193
>UniRef50_Q4P9L5 Cluster: Putative uncharacterized protein; n=1;
Ustilago maydis|Rep: Putative uncharacterized protein -
Ustilago maydis (Smut fungus)
Length = 1496
Score = 101 bits (242), Expect = 2e-20
Identities = 69/180 (38%), Positives = 95/180 (52%), Gaps = 27/180 (15%)
Frame = +1
Query: 211 SLSKELRHFHTS--HAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSD 384
S S LR F T+ ++ + L+D+GEGI E I +WFV+ G VQ+FD ICEVQSD
Sbjct: 1024 SSSTSLRSFATTPRRLAVEVKPYLLADVGEGITECEIIKWFVQPGAVVQEFDPICEVQSD 1083
Query: 385 KAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDK-PVAEIDA 561
KA+V ITSRY G I RL H A VG PL +I++ +S+ + + +D + AE+ +
Sbjct: 1084 KASVEITSRYAGKIKRLMHKEGDVAKVGHPLCEIEM-ESDGENEASDAGEQRAEQAEVTS 1142
Query: 562 PKTEQNQKI------------------------KVLTTPAVRRIAAQFKVDLSAVKATGR 669
TE + VL TPAVRR++ + VDL+ V TGR
Sbjct: 1143 SSTESESRAVNMEGFMSAEQKHSNGGGHAASDRSVLATPAVRRVSREHNVDLAQVHGTGR 1202
>UniRef50_Q4U9K9 Cluster: 2-oxoglutarate dehydrogenase complex
subunit, putative; n=2; Theileria|Rep: 2-oxoglutarate
dehydrogenase complex subunit, putative - Theileria
annulata
Length = 422
Score = 100 bits (240), Expect = 3e-20
Identities = 48/99 (48%), Positives = 62/99 (62%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
R H S + FKLSDIGEGI EV + +W VGD V++ +++C VQSDKAAV ITS
Sbjct: 30 RFLHLSSKNLALTTFKLSDIGEGINEVQLVKWEKSVGDEVEEMESVCTVQSDKAAVEITS 89
Query: 409 RYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTD 525
RY GI+ +LY + T +G PL+DID D D P +
Sbjct: 90 RYTGIVKKLYVNEGDTVKIGSPLMDIDTVDEVPDDTPNN 128
>UniRef50_A6RRC1 Cluster: Putative uncharacterized protein; n=2;
Sclerotiniaceae|Rep: Putative uncharacterized protein -
Botryotinia fuckeliana B05.10
Length = 480
Score = 97.9 bits (233), Expect = 2e-19
Identities = 51/132 (38%), Positives = 79/132 (59%), Gaps = 5/132 (3%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
++FH S + I F L+DIGEGI+E I +WFV+ V+++D +CEVQSDKA+V ITS
Sbjct: 31 KYFHASAKRSAIKPFMLADIGEGIKECEIIQWFVEPEARVEEWDKLCEVQSDKASVEITS 90
Query: 409 RYDGIITRLYHDIDQTALVGQPLVDIDVQ-DSENDG----KPTDVAPDKPVAEIDAPKTE 573
R+ G+I +L+++ A VG+ L+DID+Q + E +G + + D +D TE
Sbjct: 91 RFSGVIKKLHYEAGDMAQVGKALLDIDIQGEIEQEGASAVEGSSAGNDSKAQPVDNSTTE 150
Query: 574 QNQKIKVLTTPA 609
+ + PA
Sbjct: 151 YKVDVPGASQPA 162
>UniRef50_Q9M724 Cluster: Branched chain alpha-keto acid
dehydrogenase E2 subunit; n=9; Magnoliophyta|Rep:
Branched chain alpha-keto acid dehydrogenase E2 subunit
- Arabidopsis thaliana (Mouse-ear cress)
Length = 483
Score = 97.5 bits (232), Expect = 3e-19
Identities = 48/136 (35%), Positives = 76/136 (55%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
++ L+ GEGI E + +WFVK GD+V++F +CEVQSDKA + ITSR+ G + + H
Sbjct: 75 LIDVPLAQTGEGIAECELLKWFVKEGDSVEEFQPLCEVQSDKATIEITSRFKGKVALISH 134
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRI 621
VG+ LV + V+DS++ TD + + K + L+TPAVR +
Sbjct: 135 SPGDIIKVGETLVRLAVEDSQDSLLTTD---SSEIVTLGGSKQGTENLLGALSTPAVRNL 191
Query: 622 AAQFKVDLSAVKATGR 669
A +D++ + TG+
Sbjct: 192 AKDLGIDINVITGTGK 207
>UniRef50_A0D1R4 Cluster: Chromosome undetermined scaffold_34, whole
genome shotgun sequence; n=3; Paramecium
tetraurelia|Rep: Chromosome undetermined scaffold_34,
whole genome shotgun sequence - Paramecium tetraurelia
Length = 419
Score = 97.5 bits (232), Expect = 3e-19
Identities = 53/153 (34%), Positives = 85/153 (55%), Gaps = 8/153 (5%)
Frame = +1
Query: 235 FHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRY 414
F + + + FKL D+GE I+E IK+W VK+GD+V +FD + +V +DK I S Y
Sbjct: 7 FLSRYYFGAVKIFKLPDLGEKIKEATIKKWHVKIGDHVNEFDPVADVSTDKMFTQIPSNY 66
Query: 415 DGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKV 594
G I +L+H D+T LVG ++I++ +S+N T V + + E +Q I+
Sbjct: 67 TGKIHKLFHQEDETCLVGGDFLEIEI-ESDNQESATPQTQHHQVKQEVTKQQEVHQTIQT 125
Query: 595 --------LTTPAVRRIAAQFKVDLSAVKATGR 669
L TPAVR +A Q +DL+ ++ +G+
Sbjct: 126 NNNASNHKLATPAVRHLAKQKGIDLNKIQGSGQ 158
>UniRef50_Q9YBC6 Cluster: Pyruvate dehydrogenase complex, E2
component; n=1; Aeropyrum pernix|Rep: Pyruvate
dehydrogenase complex, E2 component - Aeropyrum pernix
Length = 412
Score = 91.5 bits (217), Expect = 2e-17
Identities = 57/146 (39%), Positives = 77/146 (52%), Gaps = 8/146 (5%)
Frame = +1
Query: 253 VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR 432
+ +IV KL DIGEGI E I EW V+ G V+QF + V + KA V I S Y G + R
Sbjct: 1 MGRIVQVKLPDIGEGIAEGEIVEWLVEEGAVVKQFSPLVRVLTAKATVEIPSPYTGRVVR 60
Query: 433 LYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQ--------NQKI 588
L VG P+++I+V++ E P A +KP A ++ PK E+ I
Sbjct: 61 LLAKPGDVVRVGDPIIEIEVEEGEAPKAPE--AAEKPSATVEPPKAEEAAAPPPQAAPAI 118
Query: 589 KVLTTPAVRRIAAQFKVDLSAVKATG 666
V P VRR+A Q VDL+ V+ TG
Sbjct: 119 LVRAPPRVRRLARQLGVDLARVRGTG 144
>UniRef50_Q2UJZ9 Cluster: Dihydrolipoamide transacylase; n=9;
Eurotiomycetidae|Rep: Dihydrolipoamide transacylase -
Aspergillus oryzae
Length = 476
Score = 91.1 bits (216), Expect = 2e-17
Identities = 57/174 (32%), Positives = 93/174 (53%), Gaps = 21/174 (12%)
Frame = +1
Query: 211 SLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKA 390
++S R FH + A+ + + L D+GEGI EV I +W+V+ G +++++ +C+ QSDKA
Sbjct: 31 TISFPRRTFHAAPALWGVKSQILKDVGEGITEVQIIQWYVEEGAHIEEWKPLCQYQSDKA 90
Query: 391 AVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSE--NDGKPTDVAP---------- 534
ITSRY+GI+ +L+ D T G+ L DI+V+D + D P + AP
Sbjct: 91 VDDITSRYEGIVKKLHFQADDTVPTGRALCDIEVEDGKYPEDNPPPEPAPAPAQPSPAPA 150
Query: 535 ----DKPVAEIDA----PKTEQN-QKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
+P E+ A P+ +N + L TPAVR + V++ + TG+
Sbjct: 151 QAETKQPSVEVAATTQKPEAPKNGSRYATLATPAVRGMLKAHNVNILDIPGTGK 204
>UniRef50_Q03Y73 Cluster: Acetoin/pyruvate dehydrogenase complex, E2
component, dihydrolipoamide succinyltransferase; n=2;
Lactobacillales|Rep: Acetoin/pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
succinyltransferase - Leuconostoc mesenteroides subsp.
mesenteroides (strain ATCC 8293 /NCDO 523)
Length = 431
Score = 88.2 bits (209), Expect = 2e-16
Identities = 56/147 (38%), Positives = 75/147 (51%), Gaps = 14/147 (9%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FK+ DIGEG+ E I W VKVGD + D + EVQ+DK I S Y G +T+L+ D
Sbjct: 5 FKMPDIGEGMAEGDITSWLVKVGDTIAADDPVAEVQNDKLMQEILSPYGGKVTKLFVDAG 64
Query: 451 QTALVGQPLVDIDVQ-DSENDGKPTDVAPDKPVAEI----------DAPKTEQNQKIK-- 591
T VG PL++ D SEND VA + + APK ++
Sbjct: 65 TTVEVGDPLIEFDGDGSSENDSDNGHVAQPSTSSNVVETEQSTPKNTAPKETSTVQVANG 124
Query: 592 -VLTTPAVRRIAAQFKVDLSAVKATGR 669
VL P+VR +A + +DL+ V ATGR
Sbjct: 125 HVLAMPSVRHLAHEKNIDLTQVPATGR 151
>UniRef50_Q7RS62 Cluster: Plasmodium vivax PV1H14105_P; n=8;
Plasmodium|Rep: Plasmodium vivax PV1H14105_P -
Plasmodium yoelii yoelii
Length = 465
Score = 83.0 bits (196), Expect = 6e-15
Identities = 43/98 (43%), Positives = 61/98 (62%), Gaps = 2/98 (2%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
R +TS+ KIV KL DIGEGI EV I +W ++GD V + +++ VQSDKAAV ITS
Sbjct: 25 RFINTSNVNLKIVKCKLFDIGEGISEVEITQWNKQIGDEVSEMESLLTVQSDKAAVDITS 84
Query: 409 RYDGIITRLYHDIDQTALVGQPLVDIDVQD--SENDGK 516
+Y+GI+ + Y + +G +ID QD E +G+
Sbjct: 85 KYNGILVKKYANDKDIIKIGSYFCEIDTQDEVGEEEGE 122
>UniRef50_Q9KG97 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
halodurans|Rep: Pyruvate dehydrogenase E2 - Bacillus
halodurans
Length = 414
Score = 81.4 bits (192), Expect = 2e-14
Identities = 46/142 (32%), Positives = 74/142 (52%), Gaps = 7/142 (4%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
+V F+L D+GEG+ E I WFV+ GD+V+Q + + EVQ+DK +T+ G I R+Y+
Sbjct: 1 MVEFRLPDVGEGMHEGEIISWFVQEGDHVKQDEPVVEVQTDKMNAELTAPVSGKIKRVYY 60
Query: 442 DIDQTALVGQPLVDID-------VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLT 600
+ + A VG L ID + E + +P++ I ++ K L
Sbjct: 61 KVGEVAEVGSLLFTIDENLSTFKSETHERTKRENSTEQTRPISNISLTSQQKAPVRKGLA 120
Query: 601 TPAVRRIAAQFKVDLSAVKATG 666
TP VR++A + ++L V TG
Sbjct: 121 TPYVRQLAREMNINLEDVVGTG 142
>UniRef50_Q5KP05 Cluster: Tricarboxylic acid cycle-related protein,
putative; n=2; Filobasidiella neoformans|Rep:
Tricarboxylic acid cycle-related protein, putative -
Cryptococcus neoformans (Filobasidiella neoformans)
Length = 633
Score = 80.2 bits (189), Expect = 4e-14
Identities = 49/124 (39%), Positives = 62/124 (50%), Gaps = 1/124 (0%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
R H S A K+ FKL DIGEGI EV I +W V G V++FD +CEVQSDK+ V +TS
Sbjct: 45 RPLHQSSAALKLSPFKLHDIGEGITEVEILKWHVTDGQAVEEFDALCEVQSDKSVVELTS 104
Query: 409 RYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDV-APDKPVAEIDAPKTEQNQK 585
GI+ + D VG L I+ + D D+ AP P + E N K
Sbjct: 105 HAKGIVRDIKTDPGHMVKVGTVLCVIETDEPSEDAAEDDLQAP--PQLDNAQDSVEDNTK 162
Query: 586 IKVL 597
L
Sbjct: 163 SPTL 166
>UniRef50_Q97CK2 Cluster: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase; n=3;
Thermoplasma|Rep: Pyruvate dehydrogenase E2 /
dihydrolipoamide acetyltransferase - Thermoplasma
volcanium
Length = 400
Score = 80.2 bits (189), Expect = 4e-14
Identities = 51/134 (38%), Positives = 71/134 (52%), Gaps = 2/134 (1%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL DIGEG+ E I +W V GD V++ ++ EV +DK V I S +G I+++ +
Sbjct: 4 FKLPDIGEGVTEGEIVKWDVAEGDEVKKDQDLVEVMTDKVTVKIPSPVNGKISKILYKEG 63
Query: 451 QTALVGQPLVDIDV-QDSENDGKPTDVAPDKP-VAEIDAPKTEQNQKIKVLTTPAVRRIA 624
Q VG LV ID +++ + A KP E KVL +PAVRRIA
Sbjct: 64 QVVPVGSTLVQIDTGEETSQQTMAEEHAELKPQTTAAQQIAIETVPAGKVLASPAVRRIA 123
Query: 625 AQFKVDLSAVKATG 666
+ +DL+ VK TG
Sbjct: 124 RENGIDLAKVKGTG 137
>UniRef50_Q92BY1 Cluster: Lin1411 protein; n=15; Bacillales|Rep:
Lin1411 protein - Listeria innocua
Length = 416
Score = 78.6 bits (185), Expect = 1e-13
Identities = 49/147 (33%), Positives = 78/147 (53%), Gaps = 7/147 (4%)
Frame = +1
Query: 250 AVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIIT 429
AV KI KL GE + E I W VK GD V+++D I EV +DK I S + G I
Sbjct: 2 AVEKITMPKL---GESVTEGTISSWLVKPGDTVEKYDAIAEVLTDKVTAEIPSSFSGTIK 58
Query: 430 RLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLT--- 600
+ + D+T VG+ + I+ D+ + ++ A + E AP+ ++ +++K+
Sbjct: 59 EILAEEDETLEVGEVICTIETADAGS----SEPAEEVEQTETKAPEKQETKQVKLAEAPA 114
Query: 601 ----TPAVRRIAAQFKVDLSAVKATGR 669
+PAV RIA + +DLS V+ TG+
Sbjct: 115 SGRFSPAVLRIAGENNIDLSTVEGTGK 141
>UniRef50_A1RJV4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=25; Gammaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Shewanella sp. (strain W3-18-1)
Length = 536
Score = 77.4 bits (182), Expect = 3e-13
Identities = 52/138 (37%), Positives = 71/138 (51%), Gaps = 2/138 (1%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I F L DIGEGI E + EW V GD V++ I +V +DKA V I + G I +L++
Sbjct: 120 IEEFLLPDIGEGIVECELVEWLVSEGDWVEEDQPIADVMTDKALVQIPAIKAGKIAKLHY 179
Query: 442 DIDQTALVGQPLVDIDV-QDSENDGKPTDVAPDKPVAEI-DAPKTEQNQKIKVLTTPAVR 615
Q A V PL I+V Q + T+ A + A E ++ K L +PAVR
Sbjct: 180 RKGQLAKVHTPLFAIEVEQTASAPAATTNTDTVANAAHVAQAVSAEPARQGKALASPAVR 239
Query: 616 RIAAQFKVDLSAVKATGR 669
R+A +DLS V TG+
Sbjct: 240 RMARSLDIDLSQVPGTGK 257
Score = 62.9 bits (146), Expect = 7e-09
Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 2/100 (2%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L DIGEG+ E + EW VK GD V + I +V +DKA V I + + G++T+LY+
Sbjct: 5 FILPDIGEGVVECELVEWLVKEGDTVVEDQPIADVMTDKALVQIPAPFAGVVTKLYYAKG 64
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVA--PDKPVAEIDAP 564
A V PL + ++ + VA P A++ P
Sbjct: 65 DIAKVHAPLYAVQIEGAVEIAGEESVAAEPAATTAKVTEP 104
>UniRef50_Q23VX7 Cluster: 2-oxo acid dehydrogenases acyltransferase;
n=1; Tetrahymena thermophila SB210|Rep: 2-oxo acid
dehydrogenases acyltransferase - Tetrahymena thermophila
SB210
Length = 462
Score = 77.4 bits (182), Expect = 3e-13
Identities = 52/156 (33%), Positives = 79/156 (50%), Gaps = 20/156 (12%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I FKL D+GE I+E +K+ +VK GD V++F I +V +DK I S Y G I +++H
Sbjct: 27 IKPFKLPDLGEKIKEATVKKLYVKEGDIVEEFQTIADVATDKLFTQIPSSYAGKIHKVFH 86
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVA-------PDKPVAEIDAPKTEQNQKIK--- 591
+ T LVG V+I+V D ++ G+ + K I + T + K
Sbjct: 87 KEEDTCLVGDVFVEIEV-DEDHSGEASTATHHHEAKQEKKENTTISSGATTSTESKKSQP 145
Query: 592 ----------VLTTPAVRRIAAQFKVDLSAVKATGR 669
VL+TPAVR +A Q ++L V+ TG+
Sbjct: 146 VVDNTYENDYVLSTPAVRSLARQHNINLKNVRGTGK 181
>UniRef50_Q749T6 Cluster: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase; n=4;
Geobacter|Rep: Pyruvate dehydrogenase complex E2
component, dihydrolipoamide acetyltransferase -
Geobacter sulfurreducens
Length = 392
Score = 76.6 bits (180), Expect = 5e-13
Identities = 48/135 (35%), Positives = 76/135 (56%), Gaps = 3/135 (2%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS-RYDGIITRLYHDI 447
FKL D+GEGI E ++ W VK GD V + + EV++DKA V + S R +ITR +
Sbjct: 5 FKLPDLGEGITEAELRRWLVKEGDTVAEHQPVVEVETDKAVVEVPSPRAGRVITRARLE- 63
Query: 448 DQTALVGQPLVDIDVQDSENDGKPTDVAPDKP-VAEI-DAPKTEQNQKIKVLTTPAVRRI 621
+T +VG+ L+ I +E + P P V E+ +A + Q+ +L TP VR++
Sbjct: 64 GETVMVGETLLTI----AEEEATPPVRKPSVGIVGELPEAEEAVGTQQPAILATPLVRKL 119
Query: 622 AAQFKVDLSAVKATG 666
A + +DL+ V+ +G
Sbjct: 120 ARERGIDLATVRGSG 134
>UniRef50_Q5KUY3 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 431
Score = 75.8 bits (178), Expect = 9e-13
Identities = 44/136 (32%), Positives = 72/136 (52%), Gaps = 1/136 (0%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I FKL DIGEG+ E I W V+ GD V+ I E+Q+DKA V +T+ G + L
Sbjct: 2 IYEFKLPDIGEGLHEAEIIRWLVREGDVVKADQPIAEIQTDKAMVEMTTPVAGKVVALAG 61
Query: 442 DIDQTALVGQPLVDIDVQDS-ENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRR 618
T VG+PL+ ++ + S + P + + +PV + +T + + + + P+VR+
Sbjct: 62 PEGATVKVGEPLIVVETEASVAGEATPIEDSVREPVPVLHG-ETPRPARKRAIAAPSVRK 120
Query: 619 IAAQFKVDLSAVKATG 666
A + V + V+ TG
Sbjct: 121 RAREMGVPIDEVEGTG 136
>UniRef50_A4BTC4 Cluster: Dihydrolipoamide acetyltransferase; n=20;
Proteobacteria|Rep: Dihydrolipoamide acetyltransferase -
Nitrococcus mobilis Nb-231
Length = 382
Score = 75.4 bits (177), Expect = 1e-12
Identities = 53/148 (35%), Positives = 74/148 (50%), Gaps = 16/148 (10%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL D+GEG+ E I EWFV+VG+ +++ + V++DKA V I S G I L D
Sbjct: 4 FKLPDLGEGLVEAEIVEWFVRVGEQIERDQPLVSVETDKAIVEIPSPQTGRIEELLGDAG 63
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKP-----------VAEIDAPK---TEQNQKI 588
VG PLV ++ + T A K V E+ A + TE+ ++
Sbjct: 64 DVMHVGDPLVVFGGDEARGQEQRTSAATPKQRDESSRESTTVVGEVRAGEEVITEKAAEV 123
Query: 589 K--VLTTPAVRRIAAQFKVDLSAVKATG 666
V TPAVR +A + VDL+AV TG
Sbjct: 124 SRGVRATPAVRALARRLDVDLAAVTPTG 151
>UniRef50_A3WJV9 Cluster: Apha keto acid dehydrogenase complex, E2
component; n=2; Alteromonadales|Rep: Apha keto acid
dehydrogenase complex, E2 component - Idiomarina baltica
OS145
Length = 515
Score = 74.1 bits (174), Expect = 3e-12
Identities = 48/140 (34%), Positives = 72/140 (51%), Gaps = 7/140 (5%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L DIGEGI E I EW V GD V++ + EV +DKA V I ++ DG + +LYH
Sbjct: 106 FILPDIGEGIVECEIVEWLVSEGDEVKEDQPVVEVMTDKATVEIPAKEDGKVVKLYHKKG 165
Query: 451 QTALVGQPLVDIDVQDSENDGKPT-DVA----PDKPVAEID--APKTEQNQKIKVLTTPA 609
A V +PL + K T D A + P D A + ++ K + +PA
Sbjct: 166 DIAEVHKPLFALQPAGGVEPSKQTKDSAQAQQKNTPSQSADGGAEPAQPARQGKAVASPA 225
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + ++++ V +G+
Sbjct: 226 VRRLARENSINIADVPGSGK 245
Score = 69.3 bits (162), Expect = 8e-11
Identities = 38/91 (41%), Positives = 53/91 (58%), Gaps = 3/91 (3%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L DIGEGI E I EW V GD V++ + EV +DKA V I ++ DG++ +LY+
Sbjct: 5 FILPDIGEGIVECEIVEWLVAEGDTVKEDQPVVEVMTDKAMVEIPAKDDGVVEKLYYQKG 64
Query: 451 QTALVGQPLVDIDVQ-DSENDGKPT--DVAP 534
A V +PL I+ + D+ +D P D AP
Sbjct: 65 DIAKVHEPLFRINAEGDASDDAAPASDDAAP 95
>UniRef50_A7AQM6 Cluster: Dihydrolipoamide succinyltransferase,
putative; n=1; Babesia bovis|Rep: Dihydrolipoamide
succinyltransferase, putative - Babesia bovis
Length = 402
Score = 74.1 bits (174), Expect = 3e-12
Identities = 37/115 (32%), Positives = 60/115 (52%), Gaps = 4/115 (3%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
R H S + ++ KL +G+ I E + EW VG++V+ + I V++DK V I S
Sbjct: 44 RSLHVSSTLLEVKTMKLPSLGDSISEGTLSEWKKNVGESVEVDEPIAIVETDKVTVDINS 103
Query: 409 RYDGIITRLYHDIDQTALVGQPLVDIDVQDS----ENDGKPTDVAPDKPVAEIDA 561
G+I + ++++D T LVG+P +D+D S D +PVAE+ A
Sbjct: 104 TLSGVIVKQHYEVDDTVLVGKPFIDVDAGGSAAAPAETASGVDSKSPEPVAEVKA 158
>UniRef50_A6TMP1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Alkaliphilus
metalliredigens QYMF|Rep: Catalytic domain of components
of various dehydrogenase complexes - Alkaliphilus
metalliredigens QYMF
Length = 438
Score = 73.3 bits (172), Expect = 5e-12
Identities = 33/106 (31%), Positives = 57/106 (53%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
+V FK DIGEGI E ++ +W VK GDN+++ +++CEV++DK + S G++ L
Sbjct: 1 MVEFKFPDIGEGISEGILTKWMVKAGDNIKEGESLCEVETDKVTTELPSPATGLVNSLKG 60
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQN 579
+ T VG +V ID D + + +++ + E+N
Sbjct: 61 EEGDTIYVGDVIVKIDTGDHAEEESKNRTTSESNEKKLEKVEEEEN 106
>UniRef50_Q5ZV80 Cluster: Dihydrolipoamide acetyltransferase; n=5;
Legionellales|Rep: Dihydrolipoamide acetyltransferase -
Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 370
Score = 72.9 bits (171), Expect = 6e-12
Identities = 45/135 (33%), Positives = 67/135 (49%), Gaps = 3/135 (2%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ + I EWFVK GD V+ + +++ KA V + G I +LY
Sbjct: 4 FNLPDLGEGLPDAEIHEWFVKEGDTVKADQPLVSMETAKAVVDVPCPQSGTIAKLYGKPG 63
Query: 451 QTALVGQPLVDIDVQDSENDGKPT---DVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRI 621
G+PLV + K T ++ V+E + Q +V TTPAVR +
Sbjct: 64 DVIKTGEPLVAFVSTTEKPADKGTVVGNLEESTDVSEDNFIIGSQRSSHRVKTTPAVRLL 123
Query: 622 AAQFKVDLSAVKATG 666
A + VDLS++K +G
Sbjct: 124 AKKLGVDLSSLKGSG 138
>UniRef50_Q9X6X2 Cluster: Lipoamide acyltransferase; n=3;
Cystobacterineae|Rep: Lipoamide acyltransferase -
Myxococcus xanthus
Length = 416
Score = 72.9 bits (171), Expect = 6e-12
Identities = 47/139 (33%), Positives = 74/139 (53%), Gaps = 4/139 (2%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I FKL D+GEG+ E + +W VK GD+V++ + EV +DKA VT+ + G + + +
Sbjct: 3 IFEFKLPDLGEGVMEGELVKWHVKAGDSVKEDQVLAEVMTDKATVTVPAPKAGRVVKTHG 62
Query: 442 DIDQTALVGQPLVDIDVQ---DSENDGKPTDVAP-DKPVAEIDAPKTEQNQKIKVLTTPA 609
+ A V Q LV ++V+ ++ G AP PVA + KVL TP
Sbjct: 63 NEGDMAKVHQLLVTLEVEGAAPAQAGGHSEASAPAAAPVAGGHVGGAPASAS-KVLATPV 121
Query: 610 VRRIAAQFKVDLSAVKATG 666
RR+A + +DL+++ TG
Sbjct: 122 TRRMAREHGLDLASIAGTG 140
>UniRef50_A4WK39 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Pyrobaculum|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Pyrobaculum arsenaticum (strain DSM 13514 / JCM 11321)
Length = 408
Score = 72.1 bits (169), Expect = 1e-11
Identities = 46/135 (34%), Positives = 72/135 (53%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
++ FK D+GEG+ E I +W VK GD V++ D + +V ++KA VT+ + G + +++
Sbjct: 1 MIEFKFPDLGEGLVEGEIVKWHVKEGDFVKEGDPLVDVMTEKANVTLPAPATGKVVKIFA 60
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRI 621
+ VGQ L I+ +VA + A AP E + KV+ PA RR+
Sbjct: 61 KEGEIVKVGQVLCVIE-----------EVAAQE--ASPKAPAAEASTSQKVVAMPAARRL 107
Query: 622 AAQFKVDLSAVKATG 666
A + +DLS VK TG
Sbjct: 108 ARELGIDLSKVKGTG 122
>UniRef50_Q0W153 Cluster: Pyruvate dehydrogenase complex E2,
dihydrolipoamide acetyltransferase; n=1; uncultured
methanogenic archaeon RC-I|Rep: Pyruvate dehydrogenase
complex E2, dihydrolipoamide acetyltransferase -
Uncultured methanogenic archaeon RC-I
Length = 428
Score = 71.7 bits (168), Expect = 1e-11
Identities = 50/150 (33%), Positives = 71/150 (47%), Gaps = 18/150 (12%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL D+GEGI IK+W VK GD V++ D I EV++DKA V + + G + +
Sbjct: 5 FKLPDLGEGITSGEIKKWNVKKGDKVEEDDPIAEVETDKAVVELPAPVSGTVEDIKFKEG 64
Query: 451 QTALVGQPLVDIDVQDSENDG--KPTDVAP--------DKPVAEIDAPKTEQNQ------ 582
VG + I + E P + AP +K AE P+ +
Sbjct: 65 DMVPVGSVIAVIREEGEETKAPPPPQEKAPSPVQEKAIEKATAEAKEPEVKPPAEAVGRA 124
Query: 583 --KIKVLTTPAVRRIAAQFKVDLSAVKATG 666
K+ VL TPA R +A Q VD+ ++K TG
Sbjct: 125 PGKVPVLATPATRMLAKQLGVDIESIKGTG 154
>UniRef50_A6PJ30 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Shewanella sediminis
HAW-EB3|Rep: Catalytic domain of components of various
dehydrogenase complexes - Shewanella sediminis HAW-EB3
Length = 544
Score = 70.1 bits (164), Expect = 4e-11
Identities = 45/140 (32%), Positives = 72/140 (51%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++ F L DIGEGI E + EW V G+ V + I +V +DKA V I + G I +L+
Sbjct: 121 QVEEFLLPDIGEGIVECELVEWLVSEGEQVVEDQPIADVMTDKALVQIPAIKSGKIVKLH 180
Query: 439 HDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKI---KVLTTPA 609
+ Q A V +PL ++V + E + + AE + + + + K L +PA
Sbjct: 181 YRKGQLAKVHEPLFAVEV-ELELPAAVREESEKIHTAESISASGDIKEPVAQGKALASPA 239
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A +D++ V TG+
Sbjct: 240 VRRLARSLDIDIAQVPGTGK 259
Score = 62.5 bits (145), Expect = 9e-09
Identities = 34/99 (34%), Positives = 54/99 (54%), Gaps = 1/99 (1%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I F L DIGEG+ E + EW V GD V + I +V +DKA V I + + G+I +L++
Sbjct: 2 IKEFILPDIGEGVVECELVEWLVSEGDTVSEDQPIADVMTDKALVQIPAPHAGVIKKLHY 61
Query: 442 DIDQTALVGQPLVDIDVQDSENDG-KPTDVAPDKPVAEI 555
+ A V PL +D++ + + + V D+ AE+
Sbjct: 62 AKGEIAKVHAPLYSVDIKGNSSPAIDASSVVDDQMDAEV 100
>UniRef50_P37942 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=37; Bacillales|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Bacillus subtilis
Length = 424
Score = 70.1 bits (164), Expect = 4e-11
Identities = 41/135 (30%), Positives = 66/135 (48%), Gaps = 5/135 (3%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ +GE + E I +W V GD V ++D I EV +DK + S + G IT L + QT
Sbjct: 8 MPQLGESVTEGTISKWLVAPGDKVNKYDPIAEVMTDKVNAEVPSSFTGTITELVGEEGQT 67
Query: 457 ALVGQPLVDIDVQ-----DSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRI 621
VG+ + I+ + + + + A + PVA+ + N+K +PAV R+
Sbjct: 68 LQVGEMICKIETEGANPAEQKQEQPAASEAAENPVAKSAGAADQPNKK---RYSPAVLRL 124
Query: 622 AAQFKVDLSAVKATG 666
A + +DL V TG
Sbjct: 125 AGEHGIDLDQVTGTG 139
>UniRef50_Q4UGK1 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex,
mitochondrial, putative; n=2; Theileria|Rep:
Dihydrolipoamide succinyltransferase component of
2-oxoglutarate dehydrogenase complex, mitochondrial,
putative - Theileria annulata
Length = 457
Score = 68.5 bits (160), Expect = 1e-10
Identities = 42/128 (32%), Positives = 69/128 (53%), Gaps = 2/128 (1%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I + +G+ I E + +W V VGD + D I V++DK +V + S + G++T+ +
Sbjct: 72 IKVINVPTLGDSISEGTLTKWAVSVGDYLNVDDLIAVVETDKVSVDVNSPFSGVLTKTFS 131
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPD-KPVAEIDA-PKTEQNQKIKVLTTPAVR 615
+ T LVG+PLV+ID+ GKP++ AP+ KP A+ A T+ K PA
Sbjct: 132 NTGDTILVGKPLVEIDLA-----GKPSEKAPEKKPDAKPPASTPTKPETKSPEPPKPADS 186
Query: 616 RIAAQFKV 639
+ + F+V
Sbjct: 187 KPVSSFEV 194
>UniRef50_Q9HN75 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Halobacterium salinarum|Rep: Dihydrolipoamide
S-acetyltransferase - Halobacterium salinarium
(Halobacterium halobium)
Length = 478
Score = 68.5 bits (160), Expect = 1e-10
Identities = 40/132 (30%), Positives = 62/132 (46%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ E + W V GD V + + EV++DKA V + + DG + L+
Sbjct: 5 FTLPDVGEGVAEGELVRWLVDEGDTVTEDQPVAEVETDKAQVEVPAPVDGTVQELHWAEG 64
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQ 630
VG V DV DG+ + A D + +A + P+VR +A +
Sbjct: 65 DVVPVGDLFVTFDV-----DGEASATADDGDESGDEAASATSEASGRTFAPPSVRTLARE 119
Query: 631 FKVDLSAVKATG 666
VDL +V+ +G
Sbjct: 120 LGVDLDSVEGSG 131
>UniRef50_Q5UYG4 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Halobacteriaceae|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex - Haloarcula
marismortui (Halobacterium marismortui)
Length = 545
Score = 68.5 bits (160), Expect = 1e-10
Identities = 45/151 (29%), Positives = 75/151 (49%), Gaps = 19/151 (12%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ E + W V GD V + + EV++DKAAV + S DG++ L+ ++
Sbjct: 4 FNLPDLGEGVAEGEVLTWRVSPGDAVTEDQVLAEVETDKAAVDVPSPVDGVVQELHAEVG 63
Query: 451 QTALVGQPLVDI--------------DVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKI 588
+ G+ L+ I D ++E+ G T+ A D +E A +
Sbjct: 64 EMVQTGEVLITIAEEGDAETADAAASDTDEAESAGADTEEA-DSAASEAAAADEQSGAST 122
Query: 589 -----KVLTTPAVRRIAAQFKVDLSAVKATG 666
+V +P+VRR+A + VD++AV +G
Sbjct: 123 STADGRVFASPSVRRLAREKGVDIAAVDGSG 153
>UniRef50_Q5UWH1 Cluster: Dihydrolipoamide S-acetyltransferase
component of pyruvate dehydrogenase complex E2; n=3;
Halobacteriaceae|Rep: Dihydrolipoamide
S-acetyltransferase component of pyruvate dehydrogenase
complex E2 - Haloarcula marismortui (Halobacterium
marismortui)
Length = 540
Score = 68.5 bits (160), Expect = 1e-10
Identities = 49/149 (32%), Positives = 76/149 (51%), Gaps = 16/149 (10%)
Frame = +1
Query: 256 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
N + F+L D+GEG+ E + W V+ GD V + + EV++DKA V + S DG++ L
Sbjct: 31 NMVREFELPDVGEGVAEGELLRWRVEPGDAVSEDQPVAEVETDKAVVDVPSPVDGVVEEL 90
Query: 436 YHDIDQTALVGQPLVDIDVQDSENDGKPTDVAP-DKPVA------EIDA---PKTEQ--- 576
+ VG ++ V D E+ K T+ AP D A E+ A P E
Sbjct: 91 RAAEGEMVPVGDVIIVFRV-DGEDGPKATETAPADDTTAGSGQQTEVGATAQPAEETQSE 149
Query: 577 ---NQKIKVLTTPAVRRIAAQFKVDLSAV 654
Q+++V P+VRR+A + VD+S+V
Sbjct: 150 PAITQRVQVPAPPSVRRLARELGVDISSV 178
>UniRef50_Q83DQ8 Cluster: Dehydrogenase, E2 component,
acyltransferase; n=5; Gammaproteobacteria|Rep:
Dehydrogenase, E2 component, acyltransferase - Coxiella
burnetii
Length = 378
Score = 68.1 bits (159), Expect = 2e-10
Identities = 41/136 (30%), Positives = 67/136 (49%), Gaps = 8/136 (5%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL D+GEG+ + I+EW++ VGD V+ + +++ KA V + S G I +L+ ++
Sbjct: 4 FKLPDLGEGLPDATIREWYIAVGDEVKIDQPLVAMETAKALVDVPSPLAGKIEKLFGEVG 63
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDV------APDKPVAEIDA--PKTEQNQKIKVLTTP 606
G PL+ + + + K T D + E A P + +K TP
Sbjct: 64 DVIETGSPLIGFEGEAETEEPKDTGTVVGAIETSDTVLEESGAGIPVKKAAEKKNFKATP 123
Query: 607 AVRRIAAQFKVDLSAV 654
AVR +A Q VDL+ +
Sbjct: 124 AVRMLAKQLGVDLTKI 139
>UniRef50_A6FIQ1 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamideacyltransferase (E2) component;
n=1; Moritella sp. PE36|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex dihydrolipoamideacyltransferase
(E2) component - Moritella sp. PE36
Length = 396
Score = 68.1 bits (159), Expect = 2e-10
Identities = 49/152 (32%), Positives = 72/152 (47%), Gaps = 20/152 (13%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL D+GEG+ E I EWF+K GD V + +++ KA V I + I+ +LY +
Sbjct: 4 FKLPDLGEGLPEAEIVEWFIKPGDVVAADQLMVSMETAKAIVEIPCPENAIVVKLYGESG 63
Query: 451 QTALVGQPLVDI----DVQDSENDGKPTDVAPDKP--------VAEI--------DAPKT 570
G PLV+ D SEN T+ A + V E+ + P++
Sbjct: 64 DIIHTGDPLVEFVEEGDAISSENGAATTNGATTREPVKASTSVVGELHTSETKLKETPQS 123
Query: 571 EQNQKIKVLTTPAVRRIAAQFKVDLSAVKATG 666
I V TPAVR +A ++ +DLS V +G
Sbjct: 124 VSGNSIGVKATPAVRALAHRYNIDLSIVTPSG 155
>UniRef50_A3UGB6 Cluster: Dihydrolipoamide acetyltransferase; n=2;
Alphaproteobacteria|Rep: Dihydrolipoamide
acetyltransferase - Oceanicaulis alexandrii HTCC2633
Length = 437
Score = 68.1 bits (159), Expect = 2e-10
Identities = 37/112 (33%), Positives = 58/112 (51%), Gaps = 5/112 (4%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
+KL D+GEG+ E I EW +K GD V + +I +V +DKA V I +G++ + +
Sbjct: 6 YKLPDVGEGVVEAEIVEWHIKAGDKVTEDQHILDVMTDKATVEIPCAVNGVVKSIVGEPG 65
Query: 451 QTALVGQPLVDIDV-----QDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIK 591
+ VG ++ IDV D EN +P K ++ +APK E + K
Sbjct: 66 EVIAVGTEILVIDVDGEVPDDVENTAEPETKDAPKEESKAEAPKEEPKPEPK 117
>UniRef50_Q7RIU5 Cluster: 2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase, putative; n=12;
cellular organisms|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase, putative
- Plasmodium yoelii yoelii
Length = 1632
Score = 68.1 bits (159), Expect = 2e-10
Identities = 51/178 (28%), Positives = 85/178 (47%), Gaps = 4/178 (2%)
Frame = +1
Query: 82 AMSILVRRSVFQLRTVNRCRKIKVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNK 261
A S+ +RS+F+ ++ R + Q NG+ + + N + + ++ T
Sbjct: 1197 ATSLFRKRSIFE--SIFRKKSKNCIKQLIYNGNNVK-RAFFNVEFRQLVNNYITCKRHFS 1253
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I K+ +G+ I E VI EW KVGD V + + + +DK +V I S+ G + +++
Sbjct: 1254 IDTLKVPRLGDSITEGVINEWKKKVGDYVYSDETLAVIDTDKVSVDINSKSSGALHKIFA 1313
Query: 442 DIDQTALVGQPLVDID--VQDSEND-GKPTDVAPDKPVAEIDAPK-TEQNQKIKVLTT 603
+ LV PL +ID Q +END K +V +K + D K T N+ IK T
Sbjct: 1314 EAGDVVLVDSPLCEIDTSAQPNENDIKKNVEVDYEKKLEVNDEIKHTNNNEDIKTKET 1371
>UniRef50_A6GB59 Cluster: Alpha keto acid dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Plesiocystis pacifica SIR-1|Rep: Alpha keto acid
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Plesiocystis pacifica SIR-1
Length = 435
Score = 67.3 bits (157), Expect = 3e-10
Identities = 39/133 (29%), Positives = 61/133 (45%), Gaps = 2/133 (1%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
+V FKL +IGEG+ E I +W + G++ D + EV +DKA + I + +DG++
Sbjct: 1 MVEFKLPEIGEGVIEGEIVQWLIAPGNSFATNDGLVEVMTDKATIEIPAPFDGVLREQRA 60
Query: 442 DIDQTALVGQPLVDID--VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVR 615
VG + ++ S P AP P A A +L TPA R
Sbjct: 61 AEGDVCAVGSVIAILEEGAAASPEAPAPAAAAPATPAAPAPATPAPTPTDSSILATPAAR 120
Query: 616 RIAAQFKVDLSAV 654
+A + +DL+ V
Sbjct: 121 ALAREHDIDLARV 133
>UniRef50_Q6L1M0 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Thermoplasmatales|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Picrophilus torridus
Length = 386
Score = 67.3 bits (157), Expect = 3e-10
Identities = 42/130 (32%), Positives = 63/130 (48%), Gaps = 2/130 (1%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ IGEG+ E I +W VK GD +++ I E+ +DK + I S G + +L +
Sbjct: 5 KVPPIGEGVSEGEIVKWNVKEGDTIEKDQEIVEIMTDKITIKIPSPVSGKVLKLIEPEGK 64
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQK--IKVLTTPAVRRIAA 627
T VG + ID Q+ + + A + +I+ N K V TPAVR A
Sbjct: 65 TVKVGDSIATIDSQEGNEEINNENNAQESKEIKIENKNEGSNVKNVELVKATPAVRAYAR 124
Query: 628 QFKVDLSAVK 657
Q +DLS V+
Sbjct: 125 QKGIDLSNVR 134
>UniRef50_UPI00006D8691 Cluster: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes; n=1; Pseudomonas
aeruginosa C3719|Rep: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes - Pseudomonas
aeruginosa C3719
Length = 129
Score = 66.9 bits (156), Expect = 4e-10
Identities = 41/121 (33%), Positives = 64/121 (52%), Gaps = 5/121 (4%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL D+GEG++E I EW VK GD+V+ + V++ KA V I + YDG++ +L+
Sbjct: 4 FKLPDLGEGLQEAEIVEWHVKAGDSVRADQRLVSVETAKALVDIPAPYDGVVGKLFGAEG 63
Query: 451 QTALVGQPLVDIDVQDSENDGK-----PTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVR 615
VG+PLV + ++++ + VAP + V+ AP TPAVR
Sbjct: 64 DILHVGEPLVGFEGEEADAGYRGGASWRAAVAPWRTVSS-SAPHRPPASTWHSRATPAVR 122
Query: 616 R 618
+
Sbjct: 123 Q 123
>UniRef50_Q9RPS3 Cluster: Dihydrolipoamide acyltransferase; n=3;
Lactobacillales|Rep: Dihydrolipoamide acyltransferase -
Enterococcus faecalis (Streptococcus faecalis)
Length = 432
Score = 66.9 bits (156), Expect = 4e-10
Identities = 40/144 (27%), Positives = 74/144 (51%), Gaps = 12/144 (8%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ +GE + E I +W VK GD+V+++D + EV SDK + S ++ R+
Sbjct: 7 KMPHLGESVTEAAIVQWLVKPGDSVKRYDPLMEVVSDKVTTEVPSDFEWCSKRISDFSRY 66
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTT---------- 603
+G ++ ++ +++ + T+VA PV E A + ++++ + +T
Sbjct: 67 RVPIGTAVMTLETEETT---EKTEVATLAPVKEASAEQAQEHETVATTSTATSHQKNNGR 123
Query: 604 --PAVRRIAAQFKVDLSAVKATGR 669
PAV +IA + K+DL+ V TGR
Sbjct: 124 YSPAVLKIAQEKKIDLTQVTGTGR 147
>UniRef50_P09062 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=27; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas putida
Length = 423
Score = 66.9 bits (156), Expect = 4e-10
Identities = 40/105 (38%), Positives = 56/105 (53%), Gaps = 5/105 (4%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ DIGEGI +V + EWFVKVGD + + + +V +DKA V I S G + L +
Sbjct: 7 KMPDIGEGIAQVELVEWFVKVGDIIAEDQVVADVMTDKATVEIPSPVSGKVLALGGQPGE 66
Query: 454 TALVGQPLVDIDVQDSEN-----DGKPTDVAPDKPVAEIDAPKTE 573
VG L+ I+V+ S N KP +V P PVA P+ +
Sbjct: 67 VMAVGSELIRIEVEGSGNHVDVPQAKPAEV-PAAPVAAKPEPQKD 110
>UniRef50_A0JUQ7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=9; Actinobacteria
(class)|Rep: Catalytic domain of components of various
dehydrogenase complexes - Arthrobacter sp. (strain FB24)
Length = 462
Score = 66.5 bits (155), Expect = 6e-10
Identities = 40/106 (37%), Positives = 57/106 (53%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I F+L D+GEG+ E I W V VGD V I EV++ KA V + S + G+IT L+
Sbjct: 2 IKEFRLPDLGEGLTESEILSWKVAVGDTVALNQVIAEVETAKAVVELPSPFAGVITALHE 61
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQN 579
VG+P+V +V+ +DG P+ +P A +A K E N
Sbjct: 62 QPGTVVEVGKPIVSFEVEG--DDGGPSAASP----APAEAAKREPN 101
>UniRef50_Q7D716 Cluster: 2-oxoisovalerate dehydrogenase E2
component, dihydrolipoamide acetyltransferase, putative;
n=13; Mycobacterium|Rep: 2-oxoisovalerate dehydrogenase
E2 component, dihydrolipoamide acetyltransferase,
putative - Mycobacterium tuberculosis
Length = 393
Score = 66.1 bits (154), Expect = 7e-10
Identities = 43/135 (31%), Positives = 64/135 (47%), Gaps = 1/135 (0%)
Frame = +1
Query: 256 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
+ I +F + D+GEG++EV + W V VGD+V+ +C V++ KA V I S Y G I L
Sbjct: 5 DSIRSFPVPDLGEGLQEVTVTCWSVAVGDDVEINQTLCSVETAKAEVEIPSPYAGRIVEL 64
Query: 436 YHDIDQTALVGQPLVDIDV-QDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAV 612
VG LV ID + P DA + + L P V
Sbjct: 65 GGAEGDVLKVGAELVRIDTGPTAVAQXNGEGAVPTLVGYGADAAIETSRRTSRPLAAPVV 124
Query: 613 RRIAAQFKVDLSAVK 657
R++A + VDL+A++
Sbjct: 125 RKLAKELAVDLAALQ 139
>UniRef50_Q1GTH9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Alphaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Sphingopyxis alaskensis (Sphingomonas
alaskensis)
Length = 441
Score = 66.1 bits (154), Expect = 7e-10
Identities = 36/116 (31%), Positives = 59/116 (50%), Gaps = 3/116 (2%)
Frame = +1
Query: 268 AFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDI 447
+F+L DIGEGI E I W VKVG+ V++ + ++ +DKA V + S G++ L ++
Sbjct: 5 SFRLPDIGEGIAEAEIVAWHVKVGERVEEDAQLADMMTDKATVEMESPVSGVVVELAGEV 64
Query: 448 DQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE---IDAPKTEQNQKIKVLTTP 606
+G L I+ D + DG D PV + ++ P TE+ + + P
Sbjct: 65 GDLIPIGSTLAVIET-DDDGDGALDAPPADTPVEDEMAVETPGTEEVSDAEKIPLP 119
>UniRef50_A7HBV2 Cluster: Dehydrogenase complex catalytic domain;
n=2; Anaeromyxobacter|Rep: Dehydrogenase complex
catalytic domain - Anaeromyxobacter sp. Fw109-5
Length = 454
Score = 66.1 bits (154), Expect = 7e-10
Identities = 33/97 (34%), Positives = 56/97 (57%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
+L DIGEG+ E +++WFVK GD+V + + EV +DKA V I S G + +L+ +
Sbjct: 6 ELPDIGEGVVEAEVQQWFVKPGDDVAEDQPLVEVMTDKATVVIPSPKRGRVVKLFFGVGD 65
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAP 564
A V PL++++++ + G P + A ++AP
Sbjct: 66 LAKVHSPLLELELEGAV-AGAPEGPEGPRAKATVEAP 101
>UniRef50_Q15U82 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Gammaproteobacteria|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Pseudoalteromonas atlantica (strain T6c /
BAA-1087)
Length = 555
Score = 65.7 bits (153), Expect = 1e-09
Identities = 31/79 (39%), Positives = 47/79 (59%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L DIGEGI E + EW V GD++ + + EV +DKA V I + Y G + +LY+
Sbjct: 4 FILPDIGEGIVECELLEWLVCEGDSIVEDQPVAEVMTDKATVQIPAMYSGTVKKLYYQAG 63
Query: 451 QTALVGQPLVDIDVQDSEN 507
+ A V +PL +D++ E+
Sbjct: 64 EIAQVHKPLFAMDIEGHES 82
Score = 62.9 bits (146), Expect = 7e-09
Identities = 48/149 (32%), Positives = 75/149 (50%), Gaps = 17/149 (11%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L DIGEGI E + +W V G++V + + EV +DKA V I +++ G I L +
Sbjct: 136 FILPDIGEGIVECELVKWLVSEGEDVIEDQPVVEVMTDKALVEIPAKHSGTIVSLCYQRG 195
Query: 451 QTALVGQPLVDIDVQDSENDGKP-----------TDVA-PDKPVAEIDAPKTEQNQKI-- 588
A V L + V ++ P T++ P+A + A K + + K+
Sbjct: 196 DIANVHSALFTMRVAGVDDKALPPLASATPLTSTTEITQTSTPLAGVQA-KQDTSSKMSK 254
Query: 589 ---KVLTTPAVRRIAAQFKVDLSAVKATG 666
KVL +PAVRR+A + +DLS V+ +G
Sbjct: 255 VNHKVLASPAVRRVAREQDIDLSNVQGSG 283
>UniRef50_P21883 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=80; Bacilli|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Bacillus subtilis
Length = 442
Score = 65.7 bits (153), Expect = 1e-09
Identities = 40/99 (40%), Positives = 54/99 (54%), Gaps = 2/99 (2%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL DIGEGI E I +WFVK D V + D + EVQ+DKA V I S G + L +
Sbjct: 5 FKLPDIGEGIHEGEIVKWFVKPNDEVDEDDVLAEVQNDKAVVEIPSPVKGKVLELKVEEG 64
Query: 451 QTALVGQPLVDIDVQDSEN-DGKPTDVAPD-KPVAEIDA 561
A VGQ ++ D E+ K +D + D K A++ +
Sbjct: 65 TVATVGQTIITFDAPGYEDLQFKGSDESDDAKTEAQVQS 103
>UniRef50_Q8CX89 Cluster: Pyruvate dehydrogenase E2; n=4;
Bacillaceae|Rep: Pyruvate dehydrogenase E2 -
Oceanobacillus iheyensis
Length = 420
Score = 65.3 bits (152), Expect = 1e-09
Identities = 41/144 (28%), Positives = 74/144 (51%), Gaps = 8/144 (5%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
+V KL DIGEG+ E I +F++ GD V++ I E+Q++K IT+ G + ++
Sbjct: 1 MVEVKLHDIGEGMTEGDILTYFIQEGDQVEEDQPIVEMQTEKMVAEITAPAKGTVKEIFI 60
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDV--APDKPVAEI---DAPKTEQNQK---IKVL 597
T VG ++ I+ +D+ K +++ A ++ D TE QK ++
Sbjct: 61 AEGTTISVGTTIMTIESEDAMEKTKSSEIQRAEGNQATQLSASDNQHTETKQKNGPKRIK 120
Query: 598 TTPAVRRIAAQFKVDLSAVKATGR 669
+P R++A + VD+ V+ TG+
Sbjct: 121 ASPYTRKVARELDVDIELVEGTGK 144
>UniRef50_A0K281 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Arthrobacter|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 527
Score = 65.3 bits (152), Expect = 1e-09
Identities = 38/100 (38%), Positives = 54/100 (54%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ E I W VK GD+V D +CE+++ K+ V + S + G +T L +
Sbjct: 6 FNLPDVGEGLTEAEIVSWNVKPGDSVAINDILCEIETAKSLVELPSPFAGTVTELLVPVG 65
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKT 570
T VG P+ I V D+ + G PT PVA A +T
Sbjct: 66 VTVDVGTPI--ISVSDAVS-GDPTPADAPVPVAPAAAAQT 102
>UniRef50_A0PU60 Cluster: Dihydrolipoamide S-acetyltransferase E2
component PdhC; n=3; Mycobacterium|Rep: Dihydrolipoamide
S-acetyltransferase E2 component PdhC - Mycobacterium
ulcerans (strain Agy99)
Length = 389
Score = 64.9 bits (151), Expect = 2e-09
Identities = 41/135 (30%), Positives = 66/135 (48%), Gaps = 1/135 (0%)
Frame = +1
Query: 256 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
+++ F++ D+GEG+ EV + W V VGD+V+ +C V++ KA V I S Y G I L
Sbjct: 5 DRLKCFQVPDLGEGLEEVTVTSWAVAVGDDVELNQVLCSVETAKAEVEIPSPYAGRIVEL 64
Query: 436 YHDIDQTALVGQPLVDIDVQDSENDGKPTDVA-PDKPVAEIDAPKTEQNQKIKVLTTPAV 612
VG LV ID + ++A P DA + + P V
Sbjct: 65 GGAEGDVIKVGAALVRIDTAPELSAPTNGEIAVPTLVGYGADAAIDTSRRPGRPRAAPPV 124
Query: 613 RRIAAQFKVDLSAVK 657
R++A + VDL++++
Sbjct: 125 RKLAKELMVDLASLQ 139
>UniRef50_Q8ZUR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Pyrobaculum aerophilum|Rep: Pyruvate dehydrogenase E2 -
Pyrobaculum aerophilum
Length = 383
Score = 64.9 bits (151), Expect = 2e-09
Identities = 43/132 (32%), Positives = 67/132 (50%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FK D+GEG+ E + +W VK GD V++ D + +V ++KA VT+ + G + ++
Sbjct: 3 FKFPDLGEGLVEGEVIKWHVKEGDFVKEGDPLVDVMTEKATVTLPAPTTGRVVKILVREG 62
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQ 630
+ VGQ L I+ + G T+ AP +P +V PA RR+A +
Sbjct: 63 EVVKVGQTLCVIEPAEGPAAGPQTE-APARP--------------REVAAMPAARRLAKE 107
Query: 631 FKVDLSAVKATG 666
+DLS VK TG
Sbjct: 108 LGIDLSKVKGTG 119
>UniRef50_Q9I1M0 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex (EC
2.3.1.168) (Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase); n=22; Proteobacteria|Rep:
Lipoamide acyltransferase component of branched-chain
alpha-keto acid dehydrogenase complex (EC 2.3.1.168)
(Dihydrolipoyllysine-residue (2-
methylpropanoyl)transferase) - Pseudomonas aeruginosa
Length = 428
Score = 64.9 bits (151), Expect = 2e-09
Identities = 38/93 (40%), Positives = 51/93 (54%), Gaps = 1/93 (1%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ DIGEGI EV + EW V+VGD+V + + EV +DKA V I S G I L Q
Sbjct: 7 KMPDIGEGIAEVELVEWHVQVGDSVNEDQVLAEVMTDKATVEIPSPVAGRILALGGQPGQ 66
Query: 454 TALVGQPLVDIDVQDSENDGK-PTDVAPDKPVA 549
VG L+ ++V+ + N + P P PVA
Sbjct: 67 VMAVGGELIRLEVEGAGNLAESPAAATPAAPVA 99
>UniRef50_A1R9E2 Cluster: Pyruvate dehydrogenase E2; n=2;
Actinomycetales|Rep: Pyruvate dehydrogenase E2 -
Arthrobacter aurescens (strain TC1)
Length = 493
Score = 64.5 bits (150), Expect = 2e-09
Identities = 33/96 (34%), Positives = 48/96 (50%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL D+GEG+ E + W V VGD + I EV++ K+ V + S Y G + L+ +
Sbjct: 8 FKLPDLGEGLTEAELVNWLVAVGDEIVVDQPIAEVETAKSMVEVPSPYAGTVAELHGEAG 67
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEID 558
QT VG+PL+ I + G P P +D
Sbjct: 68 QTLDVGKPLISI-ARAGSAAGSPAAAPVPAPAGSVD 102
>UniRef50_Q8EVQ0 Cluster: Dihydrolipoamide acetyltransferase of
pyruvate dehydrogenase E2 component; n=1; Mycoplasma
penetrans|Rep: Dihydrolipoamide acetyltransferase of
pyruvate dehydrogenase E2 component - Mycoplasma
penetrans
Length = 478
Score = 64.1 bits (149), Expect = 3e-09
Identities = 35/108 (32%), Positives = 60/108 (55%), Gaps = 3/108 (2%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FK +DIGEGI E + + VK GD+V+ ++ V++DK ++S +G+I+++ +
Sbjct: 4 FKFADIGEGIHEGKVSDILVKEGDSVKDGTDLFSVETDKITTEVSSPVNGVISKILIKVG 63
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPD---KPVAEIDAPKTEQNQK 585
T VG P+ +ID + + AP+ +PV + KTEQ Q+
Sbjct: 64 DTIHVGDPIFEIDDSNGSSSSAAPAQAPEVKSEPVV-VKEEKTEQVQE 110
>UniRef50_A5UTW4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=5; Chloroflexi (class)|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Roseiflexus sp. RS-1
Length = 434
Score = 63.7 bits (148), Expect = 4e-09
Identities = 37/133 (27%), Positives = 65/133 (48%), Gaps = 3/133 (2%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
L IGE + E I W +VGD V++++ + EV++DK + +TS G++ + T
Sbjct: 7 LPQIGESMTEATIGRWLKRVGDRVERYEALVEVETDKVSTEVTSITSGVLLEIATPEGAT 66
Query: 457 ALVGQPLVDIDV--QDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIK-VLTTPAVRRIAA 627
VG L I + + ++ DAP+ + ++ TP V R+AA
Sbjct: 67 VPVGALLARIGEPGEAAVSNAPEAGAGTAATTVTTDAPEPARPRRADGPPITPVVARLAA 126
Query: 628 QFKVDLSAVKATG 666
++ +DLS ++ TG
Sbjct: 127 EYGIDLSQIRGTG 139
>UniRef50_Q6MPR6 Cluster: Pyruvate dehydrogenase E2; n=1;
Bdellovibrio bacteriovorus|Rep: Pyruvate dehydrogenase
E2 - Bdellovibrio bacteriovorus
Length = 543
Score = 62.9 bits (146), Expect = 7e-09
Identities = 44/144 (30%), Positives = 68/144 (47%), Gaps = 13/144 (9%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
KL ++GEG+ E + +W VK GD+V+ I EV +DKA V + + G++ L
Sbjct: 123 KLPELGEGVTEGELVKWLVKPGDSVKADQAIAEVLTDKATVEVPTPVAGVVKELKFKSGD 182
Query: 454 TALVGQPLVDIDVQDSENDGK--PTDVAPDKPVA----EIDAPKTEQNQKI-------KV 594
VG ++ ++ K P A P A + AP + I KV
Sbjct: 183 VVKVGSTMIILEGAGGAAAPKAAPAAAAAPAPAAAPATKAAAPVATASSDIFPPVADSKV 242
Query: 595 LTTPAVRRIAAQFKVDLSAVKATG 666
L TPA RR+A + VD++++ TG
Sbjct: 243 LATPATRRLAREMGVDINSLTGTG 266
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/105 (31%), Positives = 48/105 (45%), Gaps = 2/105 (1%)
Frame = +1
Query: 256 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
N KL ++GEG+ E + +W VK GD V+ I EV +DKA V + S G++ L
Sbjct: 9 NMATDVKLPELGEGVTEGELVKWLVKPGDAVKADQAIAEVLTDKATVEVPSPVAGVVKDL 68
Query: 436 YHDIDQTALVGQPLVDIDVQDSEND--GKPTDVAPDKPVAEIDAP 564
VG ++ +D + +P AP P A AP
Sbjct: 69 KFKSGDVVKVGATMITLDGAGAAKPAAAQPAAAAP-APAASTPAP 112
>UniRef50_A6PBA2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Shewanella sediminis
HAW-EB3|Rep: Catalytic domain of components of various
dehydrogenase complexes - Shewanella sediminis HAW-EB3
Length = 377
Score = 62.5 bits (145), Expect = 9e-09
Identities = 37/132 (28%), Positives = 69/132 (52%), Gaps = 2/132 (1%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ +G + E ++ EW VK GD V++ D I +++ K A+ + + G+I+ + H T
Sbjct: 1 MPSLGADMTEGMLVEWLVKRGDPVKRGDIIAVIETQKGAIDMEVYHTGVISEILHQPVVT 60
Query: 457 ALVGQPLVDIDVQDSENDGKPTDVAP--DKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQ 630
VG + ++ Q S+ + T +AP D +ID ++ + +P VR+IA
Sbjct: 61 LPVGTVMARVETQASDREVAAT-IAPQIDTVAPQIDTAA----DRVAAIASPIVRKIAMG 115
Query: 631 FKVDLSAVKATG 666
+DL+A+K +G
Sbjct: 116 KSLDLTAIKGSG 127
>UniRef50_A0LQU7 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 546
Score = 62.5 bits (145), Expect = 9e-09
Identities = 30/83 (36%), Positives = 46/83 (55%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F+L D+GEG+ E I W V+ GD V Q I E+++ KA V + S + GI+ +
Sbjct: 7 FRLPDVGEGLTEAEITRWHVRPGDRVGQNQVIAEIETAKALVELPSPFAGIVAEILVAEG 66
Query: 451 QTALVGQPLVDIDVQDSENDGKP 519
T VG P++ IDV +++ P
Sbjct: 67 TTVPVGTPIIGIDVAAAQSGAHP 89
>UniRef50_Q98PG2 Cluster: DIHYDROLIPOAMIDE DEHYDROGENASE; n=8;
Mycoplasma|Rep: DIHYDROLIPOAMIDE DEHYDROGENASE -
Mycoplasma pulmonis
Length = 627
Score = 62.1 bits (144), Expect = 1e-08
Identities = 33/95 (34%), Positives = 52/95 (54%), Gaps = 1/95 (1%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FK +DIGEG+ E + E +VK+GD V++ D++ V++DK I S G+I ++ ++
Sbjct: 4 FKFADIGEGLHEGKVAEIYVKLGDTVKEGDSLFSVETDKITSDIPSPTGGVINKILFELG 63
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPD-KPVAE 552
T VG+ + ID P A + KP AE
Sbjct: 64 GTVHVGEEIFWIDDGSGPASDSPEPAAAEAKPAAE 98
>UniRef50_O32959 Cluster: Dihydrolipoamide succinyltransferase; n=1;
Mycobacterium leprae|Rep: Dihydrolipoamide
succinyltransferase - Mycobacterium leprae
Length = 530
Score = 61.3 bits (142), Expect = 2e-08
Identities = 43/131 (32%), Positives = 62/131 (47%), Gaps = 1/131 (0%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ ++GE + E + W K+GD+VQ + + EV +DK I S G++ + + D T
Sbjct: 123 MPELGESVTEGTVTRWLKKIGDSVQADEPLVEVSTDKVDTEIPSPVAGVLVSITTNEDTT 182
Query: 457 ALVGQPLVDIDVQ-DSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQF 633
VG L I V DS P A P A K E N V TP VR++A +
Sbjct: 183 VPVGGELARIGVTLDSIATPAPAPRAESVPSRPTPARK-EANGAPYV--TPLVRKLATEN 239
Query: 634 KVDLSAVKATG 666
+DL+ V TG
Sbjct: 240 NIDLAKVIGTG 250
Score = 41.9 bits (94), Expect = 0.014
Identities = 21/67 (31%), Positives = 33/67 (49%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+GE + E + W + GD V+ + + EV +DK I S G++T++ D T V
Sbjct: 10 LGESVTEGTVTRWLKQEGDTVELDEPLVEVSTDKVDTEIPSPAAGVLTKIIAQEDDTVEV 69
Query: 466 GQPLVDI 486
G L I
Sbjct: 70 GGELAVI 76
>UniRef50_P35489 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=4; Acholeplasmataceae|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Acholeplasma
laidlawii
Length = 544
Score = 61.3 bits (142), Expect = 2e-08
Identities = 49/157 (31%), Positives = 76/157 (48%), Gaps = 18/157 (11%)
Frame = +1
Query: 250 AVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIIT 429
A I FK +DIGEGI E I +W KVGD V++ + + V++DK + S DG I
Sbjct: 109 ASGDIYDFKFADIGEGIHEGTILQWNFKVGDKVKEGETLVVVETDKVNAELPSPVDGTIL 168
Query: 430 RLYHDIDQTALVGQPLVDIDVQDS--ENDGKPTDVAP-DKP------VAEIDAPK----- 567
+L + VG+ +V I + E P AP +P V EI+
Sbjct: 169 KLGKAEGEVIHVGETVVLIGQNGATLEQAQAPKAEAPVSEPKKGAGVVGEIEVSDDIIGG 228
Query: 568 TEQNQKI----KVLTTPAVRRIAAQFKVDLSAVKATG 666
+E+ + KVL +P R++A+ VD++ +K +G
Sbjct: 229 SEEVHVVATTGKVLASPVARKLASDLGVDIATIKGSG 265
Score = 59.7 bits (138), Expect = 6e-08
Identities = 37/98 (37%), Positives = 51/98 (52%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FK +DIGEGI E + +W KVGD V++ + + V++DK + S DG I L
Sbjct: 4 FKFADIGEGIHEGTVLQWNFKVGDKVKEGETLVIVETDKVNAELPSPVDGTIVSLGAKEG 63
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAP 564
+ VGQ +V ID DG T A P A++ AP
Sbjct: 64 EEIHVGQIIVTID------DGTGTPAAAPAP-AQVSAP 94
>UniRef50_Q63HZ8 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=14; Burkholderia|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Burkholderia pseudomallei
(Pseudomonas pseudomallei)
Length = 483
Score = 60.9 bits (141), Expect = 3e-08
Identities = 32/78 (41%), Positives = 44/78 (56%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ DIGEGI EV + W VKVGD V++ I +V +DKA+V I S G++ L
Sbjct: 7 KMPDIGEGIAEVELGLWHVKVGDRVKEDQAIADVMTDKASVEIPSPVTGVVVALGGKEGD 66
Query: 454 TALVGQPLVDIDVQDSEN 507
VG LV ++V+ N
Sbjct: 67 VLAVGSELVRLEVEGDGN 84
>UniRef50_Q234F3 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase family
protein; n=1; Tetrahymena thermophila SB210|Rep:
2-oxoglutarate dehydrogenase, E2 component,
dihydrolipoamide succinyltransferase family protein -
Tetrahymena thermophila SB210
Length = 564
Score = 60.9 bits (141), Expect = 3e-08
Identities = 37/124 (29%), Positives = 58/124 (46%)
Frame = +1
Query: 238 HTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD 417
HTS A I + +G+ I E + + KVGD V+ + +C V++DK V I S
Sbjct: 136 HTSKANFAIKTINVPSMGDSITEGQVHQMLKKVGDYVELDEVVCSVETDKTQVPIRSPEA 195
Query: 418 GIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVL 597
G+IT L+ + VG+P +D + +G A + +APK + K
Sbjct: 196 GVITELFAQEGENVNVGKPFFVLDTDGKKPEGAAKPAAAAAGAKKEEAPKKAEAAK-PAA 254
Query: 598 TTPA 609
+TPA
Sbjct: 255 STPA 258
>UniRef50_A3JES0 Cluster: 2-oxoglutarate dehydrogenase E2; n=1;
Marinobacter sp. ELB17|Rep: 2-oxoglutarate dehydrogenase
E2 - Marinobacter sp. ELB17
Length = 250
Score = 60.5 bits (140), Expect = 4e-08
Identities = 47/154 (30%), Positives = 72/154 (46%), Gaps = 21/154 (13%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L DIGEGI E + +W V GD +++ + EV +DKA V I + + G I RLY+
Sbjct: 4 FILPDIGEGIVECEVVKWLVSEGDMIEEDQPVVEVMTDKALVEIPAPHKGQIKRLYYKEG 63
Query: 451 QTALVGQPLVDIDVQDSE--------NDGKPTDVA-----PDKPVAEI--------DAPK 567
A V PL ++ + SE ND ++ A P AE + +
Sbjct: 64 DIAKVHAPLFELLEEGSEQEDGTINDNDDSASEKATASSMPASQKAETTKQASDSSGSNE 123
Query: 568 TEQNQKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
T + K +PAVRR+ ++ + L + +GR
Sbjct: 124 TASAAETKTPASPAVRRLMREYDLSLGHISGSGR 157
>UniRef50_A0XBY6 Cluster: Biotin/lipoyl attachment domain-containing
protein; n=1; Dinoroseobacter shibae DFL 12|Rep:
Biotin/lipoyl attachment domain-containing protein -
Dinoroseobacter shibae DFL 12
Length = 398
Score = 60.5 bits (140), Expect = 4e-08
Identities = 39/134 (29%), Positives = 61/134 (45%), Gaps = 6/134 (4%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+GE + E I +W V+ G + ++ D + EV++DK V + DGI+ V
Sbjct: 4 LGETMEEATIADWLVQPGQSFKRGDPLLEVETDKTMVEYPALGDGILVETLVGPGDVVEV 63
Query: 466 GQPLVDIDVQDSENDGKPTDVAPDKP------VAEIDAPKTEQNQKIKVLTTPAVRRIAA 627
G P+ I+ +D+ + + D A P VA A ++ TP RRIA
Sbjct: 64 GTPIAVIETRDAWDSVEEPDAAASSPGAAPSEVAGTAAQALVSPDAARLRATPLARRIAR 123
Query: 628 QFKVDLSAVKATGR 669
+ + LS V TGR
Sbjct: 124 ENHIALSQVTGTGR 137
>UniRef50_Q5Z123 Cluster: Putative branched-chain alpha-keto acid
dehydrogenase component; n=1; Nocardia farcinica|Rep:
Putative branched-chain alpha-keto acid dehydrogenase
component - Nocardia farcinica
Length = 510
Score = 60.1 bits (139), Expect = 5e-08
Identities = 28/80 (35%), Positives = 43/80 (53%)
Frame = +1
Query: 247 HAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGII 426
H ++ F+L D+GEG+ + + W V VGD+V I EV++ KA V + Y G +
Sbjct: 2 HDDGNVLEFRLPDLGEGLTDAELVSWSVAVGDHVDLNQTIAEVETAKAVVALPCPYAGTV 61
Query: 427 TRLYHDIDQTALVGQPLVDI 486
L D +T VG PL+ +
Sbjct: 62 AALLADPGETVPVGAPLIRV 81
>UniRef50_A6UDY3 Cluster: Biotin/lipoyl attachment domain-containing
protein; n=1; Sinorhizobium medicae WSM419|Rep:
Biotin/lipoyl attachment domain-containing protein -
Sinorhizobium medicae WSM419
Length = 437
Score = 60.1 bits (139), Expect = 5e-08
Identities = 42/146 (28%), Positives = 68/146 (46%), Gaps = 14/146 (9%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ +GE + E I W +K GD+ ++ D I E+++DK + DG + + +I
Sbjct: 7 KMPRLGETMEEGKIVGWLIKPGDSFRRGDPIIEIETDKTIAEFPALGDGRLEEVLVEIGD 66
Query: 454 TALVGQPLVDIDV--------QDSENDGKPTDVAPDKPVAEIDA---PKTEQNQK---IK 591
VG+PL +D+ +D T+ A K A D P + N K +
Sbjct: 67 MIEVGKPLARVDIVSGPDWTAEDGSAAEPETEAAVTKAEATADTAKEPPLDDNPKRPGDR 126
Query: 592 VLTTPAVRRIAAQFKVDLSAVKATGR 669
V TP RR A + +D+++V TGR
Sbjct: 127 VRATPLARRFARRSGIDINSVAGTGR 152
>UniRef50_Q14PD7 Cluster: Putative dihydrolipoyllysine-residue
acetyltransferase component e2 of pyruvate dehydrogenase
protein; n=1; Spiroplasma citri|Rep: Putative
dihydrolipoyllysine-residue acetyltransferase component
e2 of pyruvate dehydrogenase protein - Spiroplasma citri
Length = 427
Score = 59.7 bits (138), Expect = 6e-08
Identities = 46/160 (28%), Positives = 80/160 (50%), Gaps = 24/160 (15%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
+V FK +DIGEG+ E + + ++VGD ++ + V++DK I + DGI++++
Sbjct: 1 MVKFKFADIGEGLTEGKVAKIMIEVGDKIKDGVEMFAVETDKVNTEIYAPCDGIVSKINM 60
Query: 442 DIDQTALVGQPLVDID---VQDS---ENDGKPTDVAPDKPVA-----------EIDAPKT 570
+ T VG +V+ID DS +PT V ++ A + AP+
Sbjct: 61 AVGDTIYVGDVVVEIDDGTAGDSPAPATSEQPTTVPVEEEKAAGVVGAVSISNTVLAPRH 120
Query: 571 EQN-------QKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
N VL+TP VR++AA K+DL+ ++ +G+
Sbjct: 121 LPNNGSANVDSNKNVLSTPIVRKMAADLKIDLTKIQGSGQ 160
>UniRef50_A0JY25 Cluster: Biotin/lipoyl attachment domain-containing
protein; n=1; Arthrobacter sp. FB24|Rep: Biotin/lipoyl
attachment domain-containing protein - Arthrobacter sp.
(strain FB24)
Length = 109
Score = 59.3 bits (137), Expect = 8e-08
Identities = 27/79 (34%), Positives = 46/79 (58%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
++F L D+GEG+ E + EW V GD V++ + EV++ K+AV + S G + R++
Sbjct: 4 ISFPLPDLGEGLIEATVLEWLVSPGDQVERNQPLVEVETTKSAVELPSPQAGKVVRIHGG 63
Query: 445 IDQTALVGQPLVDIDVQDS 501
VG+PL+ +V D+
Sbjct: 64 PGDRINVGEPLIVFEVPDN 82
>UniRef50_A1SYC2 Cluster: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes; n=1; Psychromonas
ingrahamii 37|Rep: Dihydrolipoamide dehydrogenase E3
component of 3 enzyme complexes - Psychromonas
ingrahamii (strain 37)
Length = 431
Score = 58.8 bits (136), Expect = 1e-07
Identities = 38/147 (25%), Positives = 73/147 (49%), Gaps = 13/147 (8%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
+ KL ++ G VI W V GDN+++ D I EV++DKA + + S G++ ++ D
Sbjct: 3 IEIKLPEVVSGFESGVIASWCVNEGDNIKKGDVIFEVETDKAVIEVESPGAGVLGKILVD 62
Query: 445 IDQTALVGQPLVDIDVQDSEN----DGKPT----DVAPDKPVAEIDAPKTE-----QNQK 585
+ + + +V + + ++E+ G+P D PV+++ K + +
Sbjct: 63 SNSSPVAVDTIVGMILLENEDPSVLSGEPVITNDDANTPAPVSDVKPDKIQAVPSASSGA 122
Query: 586 IKVLTTPAVRRIAAQFKVDLSAVKATG 666
+++ +P + IAA +DLS V TG
Sbjct: 123 SRIMASPLAKVIAANNNIDLSNVVGTG 149
>UniRef50_A0LAA3 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=11;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
subunit, dihydrolipoamide succinyltransferase -
Magnetococcus sp. (strain MC-1)
Length = 446
Score = 58.8 bits (136), Expect = 1e-07
Identities = 40/145 (27%), Positives = 65/145 (44%), Gaps = 14/145 (9%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ +GE + E + +W +VGD V + + E+++DK V + S G+IT +Y +D
Sbjct: 6 KVPTLGESVTEATVVQWLKQVGDAVAVDEPLVELETDKVTVEMPSPVAGVITEIYAGVDA 65
Query: 454 TALVGQPLVDIDVQDSENDGKP----TDVAPDKPVAEIDAPKTEQNQKIKVL-------- 597
VG L +D Q S P + AP VA P +
Sbjct: 66 DVEVGAVLCVVDAQGSARVAVPAKPAAEPAPAPAVATAATPAPAVATPAPTVPVAPPSGG 125
Query: 598 --TTPAVRRIAAQFKVDLSAVKATG 666
+PAVR++ A+ +D + + ATG
Sbjct: 126 AALSPAVRKLLAEHGLDATQIPATG 150
>UniRef50_P65634 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=12; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Mycobacterium bovis
Length = 553
Score = 58.8 bits (136), Expect = 1e-07
Identities = 42/142 (29%), Positives = 63/142 (44%), Gaps = 12/142 (8%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ ++GE + E + W K+GD+VQ + + EV +DK I S G++ + D D T
Sbjct: 126 MPELGESVTEGTVIRWLKKIGDSVQVDEPLVEVSTDKVDTEIPSPVAGVLVSISADEDAT 185
Query: 457 ALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE-IDAPKTEQNQKIKVL-----------T 600
VG L I V ++ P KPV E PK E
Sbjct: 186 VPVGGELARIGVA-ADIGAAPAPKPAPKPVPEPAPTPKAEPAPSPPAAQPAGAAEGAPYV 244
Query: 601 TPAVRRIAAQFKVDLSAVKATG 666
TP VR++A++ +DL+ V TG
Sbjct: 245 TPLVRKLASENNIDLAGVTGTG 266
Score = 48.0 bits (109), Expect = 2e-04
Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 1/90 (1%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+GE + E + W + GD V+ + + EV +DK I S G++T++ D T V
Sbjct: 10 LGESVTEGTVTRWLKQEGDTVELDEPLVEVSTDKVDTEIPSPAAGVLTKIIAQEDDTVEV 69
Query: 466 GQPLVDIDVQDSENDGKPTDVAPDK-PVAE 552
G L I D+++ G+ AP+K P A+
Sbjct: 70 GGELAVIG--DAKDAGEAAAPAPEKVPAAQ 97
>UniRef50_Q5WE92 Cluster: Acetoin dehydrogenase E2 component; n=1;
Bacillus clausii KSM-K16|Rep: Acetoin dehydrogenase E2
component - Bacillus clausii (strain KSM-K16)
Length = 410
Score = 58.4 bits (135), Expect = 1e-07
Identities = 40/135 (29%), Positives = 65/135 (48%), Gaps = 8/135 (5%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+G + E I W +VG+ V + + I E+ S+K + ++ DGI+ Y D+D V
Sbjct: 9 LGMTMSEGTIVNWCKEVGEPVTKGEAIVEISSEKLTQELEAQEDGILLAKYGDVDAVMKV 68
Query: 466 GQPLVDIDVQDSE--NDGKPTDVAPDKPVAEID-APKT--EQNQK---IKVLTTPAVRRI 621
G+ L I + E AP +E D A KT +Q QK ++ TP R++
Sbjct: 69 GEVLAHIGQEGEEIPETAATPSTAPQLSTSETDTASKTPAKQGQKKGEERIFITPLARKL 128
Query: 622 AAQFKVDLSAVKATG 666
A + V++ V+ TG
Sbjct: 129 AKEHNVNIEEVEGTG 143
>UniRef50_Q3WAF9 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Frankia|Rep: Biotin/lipoyl
attachment:Catalytic domain of components of various
dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
Length = 585
Score = 58.4 bits (135), Expect = 1e-07
Identities = 30/84 (35%), Positives = 44/84 (52%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F+L D+GEG+ E I W V+VG+ V + EV++ KA V I S + G++ + +
Sbjct: 6 FRLPDLGEGLTEAEIVRWLVEVGETVTVNQPLVEVETAKAVVEIPSPFAGVLVERHGEAG 65
Query: 451 QTALVGQPLVDIDVQDSENDGKPT 522
VG PL+ ID E PT
Sbjct: 66 TELAVGTPLLTIDEPGDEPATGPT 89
>UniRef50_Q6AIE3 Cluster: Probable pyruvate dehydrogenase, E2
component, dihydrolipoamide acetyltransferase; n=2;
Desulfotalea psychrophila|Rep: Probable pyruvate
dehydrogenase, E2 component, dihydrolipoamide
acetyltransferase - Desulfotalea psychrophila
Length = 397
Score = 58.0 bits (134), Expect = 2e-07
Identities = 42/148 (28%), Positives = 71/148 (47%), Gaps = 15/148 (10%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F++ +G ++E + EW VK+GD V++ D I EV++ K + I DG+I ++
Sbjct: 4 FRMPSLGADMKEGRLVEWKVKLGDQVKRGDIIAEVETAKGVIEIEVFTDGVIEQILVQRG 63
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPV---------AEIDAPKTEQNQKI----- 588
+ VG L I E P + AP +PV A + P E +
Sbjct: 64 EKVPVGTVLATIRTA-GEQGKVPGEAAPPEPVFKYKACLIAAHREEPAAEPPPAVATAAG 122
Query: 589 -KVLTTPAVRRIAAQFKVDLSAVKATGR 669
++ +P R++AA+ V+LS V+ TG+
Sbjct: 123 KRLRISPLARKLAAELAVELSTVQGTGQ 150
>UniRef50_Q67SE5 Cluster: Pyruvate dehydrogenase E2; n=1;
Symbiobacterium thermophilum|Rep: Pyruvate dehydrogenase
E2 - Symbiobacterium thermophilum
Length = 450
Score = 58.0 bits (134), Expect = 2e-07
Identities = 27/55 (49%), Positives = 35/55 (63%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
FKL D+GEG+ E + W VK GD V + I EVQ+DKA V ITS +G + +L
Sbjct: 5 FKLPDVGEGLHEAELLRWLVKEGDTVTEDQPIMEVQTDKATVEITSPVNGRVVKL 59
Score = 38.3 bits (85), Expect = 0.17
Identities = 21/66 (31%), Positives = 29/66 (43%)
Frame = +1
Query: 469 QPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQFKVDLS 648
QP +DV P AP P A ++ + L TPA RR+A + VD++
Sbjct: 103 QPQASLDVPAPAAQPAPAPAAPPAPAPAPAAGAGPADRPRRALATPATRRLARELGVDIN 162
Query: 649 AVKATG 666
V TG
Sbjct: 163 QVPGTG 168
>UniRef50_Q4L6L6 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=3; Staphylococcus|Rep:
Branched-chain alpha-keto acid dehydrogenase E2 -
Staphylococcus haemolyticus (strain JCSC1435)
Length = 442
Score = 58.0 bits (134), Expect = 2e-07
Identities = 26/97 (26%), Positives = 51/97 (52%), Gaps = 2/97 (2%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ +GE + E I++W + VGD V +++ +CEV +DK + S G IT + +
Sbjct: 4 KMPKLGESVHEGTIEQWLISVGDYVDEYEPLCEVITDKVTAEVPSTVSGTITEILVSEGE 63
Query: 454 TALVGQPLVDIDVQDSEN--DGKPTDVAPDKPVAEID 558
T + + I+ +++N + K TD+ K +++
Sbjct: 64 TVQIDHVICKIETSETDNSTNTKNTDIETVKDSTDLN 100
>UniRef50_A4AIF6 Cluster: Dihydrolipoamide acetyltransferase; n=1;
marine actinobacterium PHSC20C1|Rep: Dihydrolipoamide
acetyltransferase - marine actinobacterium PHSC20C1
Length = 425
Score = 58.0 bits (134), Expect = 2e-07
Identities = 40/130 (30%), Positives = 58/130 (44%), Gaps = 7/130 (5%)
Frame = +1
Query: 298 IREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPL 477
+ E + W VGD V+ + ICEV +DK + + S +DG + R+ D VG +
Sbjct: 15 MEEGTMVAWLKNVGDPVRSGEPICEVATDKVDMEVESPFDGTLARIIAQPDDVYAVGDTI 74
Query: 478 VDIDVQDSENDG----KPTDVAPDKPVAEIDAPKTEQNQKIK---VLTTPAVRRIAAQFK 636
I + G +PTD AP +A I+ + + PA R A Q
Sbjct: 75 AFITTDADDLLGGLFDEPTDEAPAAAPTAAEAAPIAPPAPIETGWIPSVPAARGAAEQHN 134
Query: 637 VDLSAVKATG 666
VDLS+V TG
Sbjct: 135 VDLSSVTPTG 144
>UniRef50_A0JZU9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Micrococcineae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 518
Score = 58.0 bits (134), Expect = 2e-07
Identities = 27/72 (37%), Positives = 42/72 (58%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ E + W V VGD ++ I EV++ K+ V + S Y G + L+ +
Sbjct: 7 FLLPDLGEGLTEAELVNWLVAVGDEIRVDQPIAEVETAKSMVEVPSPYAGTVAVLHGEPG 66
Query: 451 QTALVGQPLVDI 486
QT VG+PL+ +
Sbjct: 67 QTLDVGKPLISV 78
>UniRef50_P06959 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=62; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Escherichia coli
(strain K12)
Length = 630
Score = 58.0 bits (134), Expect = 2e-07
Identities = 38/135 (28%), Positives = 65/135 (48%), Gaps = 13/135 (9%)
Frame = +1
Query: 304 EVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVD 483
EV + E VKVGD V ++ V+ DKA++ + + + G++ L ++ G ++
Sbjct: 218 EVEVTEVMVKVGDKVAAEQSLITVEGDKASMEVPAPFAGVVKELKVNVGDKVKTGSLIMI 277
Query: 484 IDVQDSENDGKPT--DVAPDKPVAEIDAPKTEQNQKIK-----------VLTTPAVRRIA 624
+V+ + P + A P A+ +AP K + V TP +RR+A
Sbjct: 278 FEVEGAAPAAAPAKQEAAAPAPAAKAEAPAAAPAAKAEGKSEFAENDAYVHATPLIRRLA 337
Query: 625 AQFKVDLSAVKATGR 669
+F V+L+ VK TGR
Sbjct: 338 REFGVNLAKVKGTGR 352
Score = 49.6 bits (113), Expect = 7e-05
Identities = 31/110 (28%), Positives = 47/110 (42%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
+ K+ DIG EV I E VKVGD V+ ++ V+ DKA++ + S GI+ +
Sbjct: 3 IEIKVPDIGAD--EVEITEILVKVGDKVEAEQSLITVEGDKASMEVPSPQAGIVKEIKVS 60
Query: 445 IDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKV 594
+ G ++ D D D P K A AP + + V
Sbjct: 61 VGDKTQTGALIMIFDSADGAADAAPAQAEEKKEAAPAAAPAAAAAKDVNV 110
Score = 36.7 bits (81), Expect = 0.51
Identities = 20/85 (23%), Positives = 37/85 (43%)
Frame = +1
Query: 295 GIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP 474
G EV + E VKVGD V+ ++ V+ DKA++ + + + G + + ++ G
Sbjct: 114 GSDEVEVTEILVKVGDKVEAEQSLITVEGDKASMEVPAPFAGTVKEIKVNVGDKVSTGSL 173
Query: 475 LVDIDVQDSENDGKPTDVAPDKPVA 549
++ +V P P A
Sbjct: 174 IMVFEVAGEAGAAAPAAKQEAAPAA 198
>UniRef50_Q7ULX6 Cluster: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex; n=10;
Bacteria|Rep: Dihydrolipoamide succinyltransferase
component of 2-oxoglutarate dehydrogenase complex -
Rhodopirellula baltica
Length = 435
Score = 57.6 bits (133), Expect = 3e-07
Identities = 44/151 (29%), Positives = 71/151 (47%), Gaps = 13/151 (8%)
Frame = +1
Query: 253 VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR 432
++ I+ ++ +GE I EV I W + GD V+ +++ E++++KA+V I + G +
Sbjct: 1 MSDIIPVEVPTVGESISEVQIGNWLKQEGDWVKSGEDLVEIETEKASVQIPAPASGYLQS 60
Query: 433 LYHDIDQTALVGQPLVDIDVQD--------SENDGKP-----TDVAPDKPVAEIDAPKTE 573
+ D+ A VGQ + I V + S N G T AP P A AP +
Sbjct: 61 ITKQSDEFAEVGQQIASIQVAEQPAGGDGGSSNGGSAPAAGNTASAP-APTASAPAPSSP 119
Query: 574 QNQKIKVLTTPAVRRIAAQFKVDLSAVKATG 666
PA +R+ + K+D S V ATG
Sbjct: 120 AKSG-GGFVMPAAQRLLDEHKLDASQVPATG 149
>UniRef50_P16263 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=95; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Bacillus subtilis
Length = 417
Score = 57.6 bits (133), Expect = 3e-07
Identities = 35/138 (25%), Positives = 67/138 (48%), Gaps = 11/138 (7%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ ++ E I E I +W + GD V+Q + + E+++DK V +T+ G++ + D
Sbjct: 5 KVPELAESISEGTIAQWLKQPGDYVEQGEYLLELETDKVNVELTAEESGVLQEVLKDSGD 64
Query: 454 TALVGQPLVDIDVQDSENDG-KPTDVAPDK----------PVAEIDAPKTEQNQKIKVLT 600
T VG+ + I E+ PT+ K P A+ + + + K + +
Sbjct: 65 TVQVGEIIGTISEGAGESSAPAPTEKTESKESVKEEKQAEPAAQEVSEEAQSEAKSRTIA 124
Query: 601 TPAVRRIAAQFKVDLSAV 654
+P+ R++A + +DLS V
Sbjct: 125 SPSARKLAREKGIDLSQV 142
>UniRef50_Q2JGZ2 Cluster: Dehydrogenase subunit; n=1; Frankia sp.
CcI3|Rep: Dehydrogenase subunit - Frankia sp. (strain
CcI3)
Length = 524
Score = 57.2 bits (132), Expect = 3e-07
Identities = 28/78 (35%), Positives = 42/78 (53%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F+L D+GEG+ E I W +VGD V + EV++ KA V + S + GI+ +
Sbjct: 6 FRLPDLGEGLTEADIVRWLAQVGDTVTVNQPLVEVETAKAVVEVPSPFAGILVETHGAEG 65
Query: 451 QTALVGQPLVDIDVQDSE 504
T VG PL+ I D++
Sbjct: 66 TTLAVGAPLLTIQTADTD 83
>UniRef50_Q0SGE5 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=3; Actinomycetales|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 417
Score = 57.2 bits (132), Expect = 3e-07
Identities = 41/146 (28%), Positives = 68/146 (46%), Gaps = 14/146 (9%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F+L D+GEG+ E + W V+VG ++ I EV++ KA V + S Y G++ L
Sbjct: 5 FRLPDLGEGLTEAELVSWAVEVGQTIELNQVIGEVETAKALVELPSPYAGVVEELLVPAG 64
Query: 451 QTALVGQPLVDIDVQDSEND---------GKPTDVAPDKPVAE---IDAPKTEQN--QKI 588
T VG P++ + + + G + A + A + AP+T + +
Sbjct: 65 ATVPVGTPIIRVATNAATEEPPARTPVLVGYGPEAAAESKRARRRLVTAPETGTSGPDRR 124
Query: 589 KVLTTPAVRRIAAQFKVDLSAVKATG 666
+ +PA R A + VDL+ V TG
Sbjct: 125 RPDASPAARATARELGVDLAVVAGTG 150
>UniRef50_P0AFG7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=24; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Escherichia coli O157:H7
Length = 405
Score = 57.2 bits (132), Expect = 3e-07
Identities = 34/132 (25%), Positives = 66/132 (50%), Gaps = 4/132 (3%)
Frame = +1
Query: 283 DIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTAL 462
D+ E + + + W K GD V + + + E+++DK + + + DGI+ + D + T +
Sbjct: 10 DLPESVADATVATWHKKPGDAVVRDEVLVEIETDKVVLEVPASADGILDAVLED-EGTTV 68
Query: 463 VGQPLVDIDVQDSENDGKPTDVAPDK----PVAEIDAPKTEQNQKIKVLTTPAVRRIAAQ 630
+ ++ +++ + GK T ++ P A EQN +PA+RR+ A+
Sbjct: 69 TSRQILG-RLREGNSAGKETSAKSEEKASTPAQRQQASLEEQNND---ALSPAIRRLLAE 124
Query: 631 FKVDLSAVKATG 666
+D SA+K TG
Sbjct: 125 HNLDASAIKGTG 136
>UniRef50_A3WC78 Cluster: Pyruvate dehydrogenase E2 component; n=2;
Alphaproteobacteria|Rep: Pyruvate dehydrogenase E2
component - Erythrobacter sp. NAP1
Length = 463
Score = 56.8 bits (131), Expect = 4e-07
Identities = 37/138 (26%), Positives = 66/138 (47%), Gaps = 4/138 (2%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYH 441
+ K+ + + E + W VKVGD + D + E+++DKA + + +G + L
Sbjct: 3 IELKMPALSPTMEEGTLARWLVKVGDEIASGDIMAEIETDKATMEFEAVDEGTLAAILVE 62
Query: 442 DIDQTALVGQPLVDI--DVQDSENDGKPT-DVAPDKPVAEIDAPKTEQNQKIKVLTTPAV 612
+ + VG + + + +D + P+ D AP A APK+ V +P
Sbjct: 63 EGTENVAVGTVIAMLAEEGEDVSDVSAPSGDAAPAPTPAPAPAPKSAPASSEGVKASPLA 122
Query: 613 RRIAAQFKVDLSAVKATG 666
+RIAA VDL++V+ +G
Sbjct: 123 KRIAANEGVDLASVEGSG 140
>UniRef50_Q4UKI7 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=135; root|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Rickettsia felis (Rickettsia azadi)
Length = 401
Score = 56.4 bits (130), Expect = 6e-07
Identities = 31/130 (23%), Positives = 67/130 (51%), Gaps = 2/130 (1%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+GE + E I +W+ K GD V+ + + E++++K + + + DG I ++ V
Sbjct: 10 LGESVTEATIAKWYKKEGDPVKTDELLLEIETEKVTLEVNAPCDGTIGKISKTDGANVAV 69
Query: 466 GQPLVDIDVQDSEND-GKPTDVAPDKPVAEIDAPK-TEQNQKIKVLTTPAVRRIAAQFKV 639
G+ + +I+ + N G + A + V + + K E+ + + P+V+++ + K+
Sbjct: 70 GEEIGEINEGAAANTAGTNNESAKAQAVTQPTSEKPVEKPAVVNNILAPSVQKLVTENKL 129
Query: 640 DLSAVKATGR 669
D + +K TGR
Sbjct: 130 DPNNIKGTGR 139
>UniRef50_Q08V09 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=2;
Cystobacterineae|Rep: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase - Stigmatella
aurantiaca DW4/3-1
Length = 533
Score = 56.0 bits (129), Expect = 8e-07
Identities = 39/140 (27%), Positives = 69/140 (49%), Gaps = 17/140 (12%)
Frame = +1
Query: 298 IREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPL 477
++E + +W KVGD + + I EV++DK+ + + + DG + ++ D DQTA VG P+
Sbjct: 132 MKEGKVVKWLKKVGDKISSGEAIAEVETDKSNLEVEAYDDGTLAKILVDADQTAQVGAPI 191
Query: 478 VDIDVQDSE-NDGKPTDVAPDKPVA-------------EIDAPKTEQNQ---KIKVLTTP 606
I + + + P AP P A + +AP Q + +V +P
Sbjct: 192 AYIAGKGGKVSVAAPAPAAPSAPAAPKAAAPSPAAAPQKSEAPAAAPRQASGEGRVRASP 251
Query: 607 AVRRIAAQFKVDLSAVKATG 666
R++A+ +DL+AV +G
Sbjct: 252 LARKMASSQGLDLAAVHGSG 271
Score = 46.0 bits (104), Expect = 8e-04
Identities = 26/93 (27%), Positives = 46/93 (49%), Gaps = 3/93 (3%)
Frame = +1
Query: 298 IREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPL 477
++E + +W KVGD V D I EV++DK+ + + + DG++ ++ A VG P+
Sbjct: 14 MKEGKLVKWLKKVGDKVSSGDAIAEVETDKSNLEVEAYDDGVLLQIVVAEGDLAQVGAPI 73
Query: 478 VDIDVQDSENDGKPTDVAPDK---PVAEIDAPK 567
+ + + + AP K P +APK
Sbjct: 74 AYVGEKGEKVEAGSKPAAPAKAEAPAQPAEAPK 106
>UniRef50_A0JS87 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Arthrobacter sp. FB24|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Arthrobacter sp. (strain FB24)
Length = 477
Score = 56.0 bits (129), Expect = 8e-07
Identities = 39/143 (27%), Positives = 60/143 (41%), Gaps = 12/143 (8%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ +G + + EW +K GD V + D + V +DK + + S +G++ L D+ T
Sbjct: 1 MPSLGADMEHGKMVEWLIKPGDYVHRGDVVAVVDTDKTVMDVESFEEGVVAELLVDVGTT 60
Query: 457 ALVGQPLVDIDVQDSENDG-----------KPTDVAPDKPVAEIDA-PKTEQNQKIKVLT 600
+G PL I + G KP A + VA A P V
Sbjct: 61 VPIGTPLARITRTPDDGAGQAGGRPAGPHAKPASGAAETAVAAAAAEPAGAAAAAAAVQV 120
Query: 601 TPAVRRIAAQFKVDLSAVKATGR 669
P VR +A Q VD + ++ TGR
Sbjct: 121 PPPVRHLAHQLGVDTAGIRGTGR 143
>UniRef50_Q97Y20 Cluster: Dihydrolipoamide S-acetyltransferase,
amino-end; n=1; Sulfolobus solfataricus|Rep:
Dihydrolipoamide S-acetyltransferase, amino-end -
Sulfolobus solfataricus
Length = 211
Score = 56.0 bits (129), Expect = 8e-07
Identities = 33/119 (27%), Positives = 60/119 (50%), Gaps = 1/119 (0%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I +W K GD VQ+ +++ ++++K T+ S GI+ ++Y + VGQ + I
Sbjct: 19 IVQWKKKEGDRVQEGEDLVIIETEKITTTVKSPVSGILLKIYAKEGEEVPVGQIIAYIGE 78
Query: 493 QDSENDGKPTDVAPDKPVAEIDAPKTEQNQKI-KVLTTPAVRRIAAQFKVDLSAVKATG 666
+ PT A + +TE+ + I +V +P RR+A + +DLS ++ TG
Sbjct: 79 IGEQPPPSPTKPALATQQQQAQPIRTEEVKVIGEVRASPRARRLAKEKGIDLSKIRGTG 137
>UniRef50_P75392 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=2; Mycoplasma|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
pneumoniae
Length = 402
Score = 56.0 bits (129), Expect = 8e-07
Identities = 36/120 (30%), Positives = 54/120 (45%), Gaps = 1/120 (0%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FK +D+GEG+ E + E KVGD ++ + + V++DK + S Y G+IT + ++
Sbjct: 5 FKFTDVGEGLHEGKVTEILKKVGDTIKVDEALFVVETDKVTTELPSPYAGVITAITTNVG 64
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAP-KTEQNQKIKVLTTPAVRRIAA 627
+GQ + ID + G AP A AP T V T P V A
Sbjct: 65 DVVHIGQVMAVID----DGAGAAAPAAPQPVSAPAPAPTPTFTPTPAPVTTEPVVEEAGA 120
>UniRef50_Q6A613 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=1;
Propionibacterium acnes|Rep: Dihydrolipoamide
acetyltransferase component of pyruvate dehydrogenase
complex - Propionibacterium acnes
Length = 469
Score = 55.2 bits (127), Expect = 1e-06
Identities = 27/71 (38%), Positives = 41/71 (57%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ D GEG+ E + W V GD V+ D +CEV++ K+ V + S + G + +L + +T
Sbjct: 6 MPDPGEGLTEGEVVSWQVSPGDTVKINDVLCEVETAKSIVELPSPFAGTVAKLCAEPGET 65
Query: 457 ALVGQPLVDID 489
VG PLV ID
Sbjct: 66 VAVGTPLVTID 76
>UniRef50_Q7NB00 Cluster: AceF; n=1; Mycoplasma gallisepticum|Rep:
AceF - Mycoplasma gallisepticum
Length = 440
Score = 54.8 bits (126), Expect = 2e-06
Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
+K +D+GEG+ E V+ + +VKVGD +++ D + V++DK + + G +T + +
Sbjct: 4 YKFTDVGEGLHEGVVAQIYVKVGDTIKEGDPMFSVETDKVTTDLPAPEGGKVTAILASVG 63
Query: 451 QTALVGQPLVDIDVQDSE----NDGKPTDVAPDKPVAEIDAP 564
QT VG+ ++ ++ S P VAP V P
Sbjct: 64 QTVHVGEVMLVLNGDGSSAPAAAPATPAFVAPTPAVTPAPTP 105
>UniRef50_A0H5V3 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Chloroflexus aggregans DSM 9485|Rep:
Dihydrolipoamide S-succinyltransferase - Chloroflexus
aggregans DSM 9485
Length = 435
Score = 54.8 bits (126), Expect = 2e-06
Identities = 39/139 (28%), Positives = 63/139 (45%), Gaps = 12/139 (8%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+ + + E + W KVGD + D I E+++DKA + + + G++ ++ QT +
Sbjct: 9 LSDTMSEGTVGRWLKKVGDQIAVGDIIAEIETDKATMELEAFESGVLQQILVPEGQTVPI 68
Query: 466 GQPLVDIDVQDSENDGKPT------------DVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
GQP+ I + PT AP VA A T+ N +IK +P
Sbjct: 69 GQPIAIIGDGSAPIATPPTAPPASTTPHSSPAPAPATAVASPPAISTDDNGRIK--ASPV 126
Query: 610 VRRIAAQFKVDLSAVKATG 666
RR+A + +DL V TG
Sbjct: 127 ARRLAEELGIDLRQVVGTG 145
>UniRef50_P10802 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=47; Bacteria|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex - Azotobacter vinelandii
Length = 638
Score = 54.8 bits (126), Expect = 2e-06
Identities = 41/137 (29%), Positives = 67/137 (48%), Gaps = 6/137 (4%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ DIG + VI E VK GD VQ ++ ++SDKA++ I S G++ + ++
Sbjct: 226 KVPDIGSAGKARVI-EVLVKAGDQVQAEQSLIVLESDKASMEIPSPAAGVVESVAVQLNA 284
Query: 454 TALVGQPLVDIDVQDSEND-----GKPTDVAPDKPVAEIDAPKTEQNQK-IKVLTTPAVR 615
G ++ + V + G P A A AP ++ KV PAVR
Sbjct: 285 EVGTGDQILTLRVAGAAPSGPRARGSPGQAAAAPGAAPAPAPVGAPSRNGAKVHAGPAVR 344
Query: 616 RIAAQFKVDLSAVKATG 666
++A +F V+L+A+ +TG
Sbjct: 345 QLAREFGVELAAINSTG 361
Score = 37.9 bits (84), Expect = 0.22
Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 1/108 (0%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
++ DIG + VI E VK GD VQ ++ ++SDKA++ I S G++ + ++
Sbjct: 121 RVPDIGSAGKARVI-EVLVKAGDQVQAEQSLIVLESDKASMEIPSPASGVVESVAIQLNA 179
Query: 454 TALVGQPLVDIDVQDSE-NDGKPTDVAPDKPVAEIDAPKTEQNQKIKV 594
G ++ + ++ P A P AP Q++KV
Sbjct: 180 EVGTGDLILTLRTTGAQAQPTAPAAAAAASPAPAPLAPAAAGPQEVKV 227
>UniRef50_UPI00005103B2 Cluster: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes; n=1; Brevibacterium
linens BL2|Rep: COG0508: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzymes - Brevibacterium
linens BL2
Length = 399
Score = 54.4 bits (125), Expect = 2e-06
Identities = 27/78 (34%), Positives = 41/78 (52%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ E + W V++GD V + EV+S K+ V + Y G I L+ +
Sbjct: 12 FILPDLGEGLTEAELISWKVEIGDEVHVDQMVVEVESAKSVVELPCPYAGRIVSLHANAG 71
Query: 451 QTALVGQPLVDIDVQDSE 504
T GQPL+ + +E
Sbjct: 72 DTVSAGQPLLSVAEASAE 89
>UniRef50_UPI000038E473 Cluster: hypothetical protein Faci_03000379;
n=1; Ferroplasma acidarmanus fer1|Rep: hypothetical
protein Faci_03000379 - Ferroplasma acidarmanus fer1
Length = 78
Score = 54.4 bits (125), Expect = 2e-06
Identities = 17/66 (25%), Positives = 43/66 (65%)
Frame = +1
Query: 292 EGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQ 471
+G+ + +I +W+VKVGD++++ +C++ + K V + + G +T+++ DI+ + G
Sbjct: 12 QGLGKAIITQWYVKVGDSIKEDTPVCQIMAGKVTVEVEGKAKGKVTKIFRDINAEIVPGD 71
Query: 472 PLVDID 489
L++++
Sbjct: 72 DLLEVE 77
>UniRef50_Q6F713 Cluster: Dihydrolipoamide S-acetyltransferase, E2
component of the pyruvate dehydrogenase complex; n=2;
Moraxellaceae|Rep: Dihydrolipoamide S-acetyltransferase,
E2 component of the pyruvate dehydrogenase complex -
Acinetobacter sp. (strain ADP1)
Length = 661
Score = 54.0 bits (124), Expect = 3e-06
Identities = 39/171 (22%), Positives = 75/171 (43%), Gaps = 2/171 (1%)
Frame = +1
Query: 148 KVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWF 327
K ++SA +++ +TP+ + +E + ++ A + +V ++ DIG + + + E
Sbjct: 80 KTESESAPAQTEVKAETPVEQVAPQETKPATSTSAASSVVEVQVPDIG--VEKATVAELL 137
Query: 328 VKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSEN 507
V VGD + + D++ ++SDKA+V + S G I + T G L+ + + N
Sbjct: 138 VSVGDEIAENDSLVLLESDKASVEVPSTVSGTIESIEVKAGDTIQEGVLLLKVKTAGASN 197
Query: 508 --DGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQFKVDLSAV 654
K V P A + ++ AV + VD +AV
Sbjct: 198 AAPAKQEAVVPTAAPVATKAETQAETPAVQSAPAGAVDVLVPDLGVDKAAV 248
Score = 50.4 bits (115), Expect = 4e-05
Identities = 41/145 (28%), Positives = 68/145 (46%), Gaps = 21/145 (14%)
Frame = +1
Query: 295 GIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP 474
G+ + + E V VGD + + ++I V+SDKA V + S GI+ ++ Q G
Sbjct: 242 GVDKAAVAEILVNVGDKITKDESIVVVESDKATVEVPSTVSGIVKAIHVKAGQDVKEGIL 301
Query: 475 LVDID------------VQDSENDGKPTDVAPDKPVAEID-AP--------KTEQNQKIK 591
LV ++ V +E P + P A+++ AP K ++ + K
Sbjct: 302 LVTVEAEGAVASAPKAPVAKAEAAPAPAAQKAEAPAAKVETAPQAGADKLTKEQEAENSK 361
Query: 592 VLTTPAVRRIAAQFKVDLSAVKATG 666
V PAVR++A + V L+ VKA+G
Sbjct: 362 VYAGPAVRKLARELGVVLAQVKASG 386
Score = 50.0 bits (114), Expect = 5e-05
Identities = 30/125 (24%), Positives = 62/125 (49%), Gaps = 2/125 (1%)
Frame = +1
Query: 295 GIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP 474
G+ + + E VKVGD + + D++ ++SDKA+V + S G++ + + G
Sbjct: 9 GVDKATVAEILVKVGDTISENDSLILLESDKASVEVPSTASGVVKSILVSLGDEVSEGTT 68
Query: 475 LVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTE-QNQKIKVLTTPAVRRIAAQFKV-DLS 648
L++++ D+ D ++ AP + + + P + Q+ K T+ + + +V D+
Sbjct: 69 LIELESGDN-TDKTESESAPAQTEVKAETPVEQVAPQETKPATSTSAASSVVEVQVPDIG 127
Query: 649 AVKAT 663
KAT
Sbjct: 128 VEKAT 132
>UniRef50_Q49XM4 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=35; Bacillales|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Staphylococcus saprophyticus subsp. saprophyticus
(strain ATCC 15305 /DSM 20229)
Length = 424
Score = 54.0 bits (124), Expect = 3e-06
Identities = 32/104 (30%), Positives = 50/104 (48%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ ++ E I E I EW +VGD+V + + I E+++DK V + S G++ L +
Sbjct: 5 KVPELAESITEGTIAEWLKQVGDSVDKGEAIVELETDKVNVEVVSEEAGVLQELLANEGD 64
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQK 585
T VGQ + + E G T AP K A +T + K
Sbjct: 65 TVEVGQAIAVV----GEGSGNNTSEAPAKQEAPKQETETSTDDK 104
>UniRef50_Q3VZH8 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Frankia|Rep: Biotin/lipoyl
attachment:Catalytic domain of components of various
dehydrogenase complexes:E3 binding - Frankia sp. EAN1pec
Length = 475
Score = 53.6 bits (123), Expect = 4e-06
Identities = 29/94 (30%), Positives = 46/94 (48%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
++ F L D+GEG+ I W V +GD + + EV++ KA V + + G++T L
Sbjct: 4 VLEFALPDLGEGLTSAEIVRWMVGIGDVIVVDQPVAEVETAKAVVEVPCPHAGVVTALAG 63
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKP 543
VG PL+ + V + +P D PD P
Sbjct: 64 PPGTAVPVGTPLITVTVDEPAE--QPAD-GPDGP 94
>UniRef50_Q1QQR6 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=2;
Proteobacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrobacter hamburgensis (strain X14 / DSM 10229)
Length = 413
Score = 53.6 bits (123), Expect = 4e-06
Identities = 34/137 (24%), Positives = 64/137 (46%), Gaps = 5/137 (3%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
++ +GE + E I +WF K GD V + + E+++DK + + + G ++ + +
Sbjct: 5 RVPTLGESVTEATIGKWFKKAGDAVAVDEPLVELETDKVTIEVPAPSAGTLSEIVAKDGE 64
Query: 454 TALVGQPLVDID-----VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRR 618
T VG L I V+ + +P AP A P +++ P+VR+
Sbjct: 65 TVAVGALLGQISEGAAPVKATAPAAQPAAAAPASAAAVSPVP-AQKSPPPDAPLAPSVRK 123
Query: 619 IAAQFKVDLSAVKATGR 669
++A+ VD S V +G+
Sbjct: 124 LSAESGVDASTVPGSGK 140
>UniRef50_Q89AQ9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=4; Buchnera aphidicola|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Buchnera aphidicola
subsp. Baizongia pistaciae
Length = 410
Score = 53.6 bits (123), Expect = 4e-06
Identities = 39/139 (28%), Positives = 65/139 (46%), Gaps = 8/139 (5%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ DIG + EV+ E VK+GD V++ D++ V+ KA++ I + + G I + I +
Sbjct: 1 MPDIGTDLVEVI--EILVKIGDQVKKDDSLITVEGQKASIEIPASHTGTIKNIIVHIGEK 58
Query: 457 ALVGQPLVDIDVQD----SENDGKPTDVAPDKPVAEI----DAPKTEQNQKIKVLTTPAV 612
G + ++ D S+ND K + + N+ I V TP V
Sbjct: 59 ITTGSLIAILNGIDDNVKSKNDSSSYSFKNSKNTSTNSNLGNVNNNINNRTILVHATPTV 118
Query: 613 RRIAAQFKVDLSAVKATGR 669
RR+A +F + L + TGR
Sbjct: 119 RRLARKFDIKLENITGTGR 137
>UniRef50_A0G738 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=4; Burkholderiaceae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Burkholderia phymatum STM815
Length = 382
Score = 53.2 bits (122), Expect = 5e-06
Identities = 37/136 (27%), Positives = 66/136 (48%), Gaps = 1/136 (0%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
++ F L +G + E + EW +K GD V + + V + KAAV I S Y+G + L
Sbjct: 1 MIEFTLPSMGADMDEGTLLEWKIKPGDAVTKGQIVAIVDTSKAAVDIESWYEGTVYELIT 60
Query: 442 DIDQTALVGQPL-VDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRR 618
+ + VG P+ + ++ +S ++ K A + + Q +K+ +PA R+
Sbjct: 61 EPGEKIPVGTPMAIFLERGESASELKKRTGAISAAGSPLSVDAVAQRRKV----SPAARK 116
Query: 619 IAAQFKVDLSAVKATG 666
A + VDL +V +G
Sbjct: 117 HAHECHVDLDSVVGSG 132
>UniRef50_UPI00006A2AB5 Cluster: UPI00006A2AB5 related cluster; n=2;
Xenopus tropicalis|Rep: UPI00006A2AB5 UniRef100 entry -
Xenopus tropicalis
Length = 597
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/131 (25%), Positives = 60/131 (45%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
++ ++ + W K G+++ D + EV++DKA V I + G++ +
Sbjct: 6 RMPEVAANATHATLVRWAKKEGESIAVGDCLAEVETDKAIVEINADSAGVMGQWLVPAGH 65
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQF 633
VG PL + +G+ DVAP P AP Q ++ +P RR+AA+
Sbjct: 66 VVEVGAPLAVL-----RAEGEAADVAPAAPP---PAPAMTQGSGARLRASPLARRLAAEH 117
Query: 634 KVDLSAVKATG 666
+DL+ + +G
Sbjct: 118 GIDLTHLSGSG 128
>UniRef50_Q8PQ85 Cluster: Dihydrolipoamide acyltransferase; n=7;
Xanthomonas|Rep: Dihydrolipoamide acyltransferase -
Xanthomonas axonopodis pv. citri
Length = 505
Score = 52.8 bits (121), Expect = 7e-06
Identities = 25/78 (32%), Positives = 40/78 (51%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ + I EWFVK GD V+ D + +++ KA V + S + G + +L
Sbjct: 7 FHLPDLGEGLPDATIVEWFVKEGDTVRLDDPLVSMETAKAVVEVPSPFSGTVVKLAGAAG 66
Query: 451 QTALVGQPLVDIDVQDSE 504
+ G L + S+
Sbjct: 67 DVIVTGSVLAQFALDASQ 84
>UniRef50_Q2UQN3 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Trichocomaceae|Rep: Dihydrolipoamide succinyltransferase
- Aspergillus oryzae
Length = 448
Score = 52.8 bits (121), Expect = 7e-06
Identities = 38/123 (30%), Positives = 64/123 (52%), Gaps = 3/123 (2%)
Frame = +1
Query: 217 SKELRHFHTS--HAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDK 387
S +LR F S HA KI+ + + E I E V+ + +VGD V+Q + + +++DK
Sbjct: 52 SLQLRQFSASALHAAETKIIC--VPSMAESISEGVLSTFNRQVGDYVEQDEEVASIETDK 109
Query: 388 AAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPK 567
V + + G+IT+L + T VGQ +++I +++ + T +P P AE K
Sbjct: 110 IDVAVNAPQSGMITKLIVNEGDTVTVGQAVIEISLEERDT----TSQSPLPPQAE-QTSK 164
Query: 568 TEQ 576
T Q
Sbjct: 165 TPQ 167
>UniRef50_Q59638 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=7; Proteobacteria|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Pseudomonas
aeruginosa
Length = 547
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/132 (25%), Positives = 65/132 (49%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
++ DIG G EV+ E VK GD V+ ++ ++SDKA++ I S G++ + +
Sbjct: 6 RVPDIGNGEGEVI--ELLVKPGDKVEADQSLLTLESDKASMEIPSPKAGVVKSIKAKVGD 63
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQF 633
T G +++++V+ E +P + + A+ +APK E + PA A+
Sbjct: 64 TLKEGDEILELEVEGGE---QPAEAKAEAAPAQPEAPKAEAPAPAPSESKPAAPAAASVQ 120
Query: 634 KVDLSAVKATGR 669
+ + + + G+
Sbjct: 121 DIKVPDIGSAGK 132
Score = 48.8 bits (111), Expect = 1e-04
Identities = 44/158 (27%), Positives = 69/158 (43%), Gaps = 19/158 (12%)
Frame = +1
Query: 250 AVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIIT 429
A + K+ DIG + VI E VK GD V+ ++ ++SDKA++ I S G++
Sbjct: 115 AAASVQDIKVPDIGSAGKANVI-EVMVKAGDTVEADQSLITLESDKASMEIPSPASGVVE 173
Query: 430 RLYHDIDQTALVGQPLVDIDVQDS------------------ENDGKPTDVAPDKPVAEI 555
+ + G ++ + V+ + + KP AP A+
Sbjct: 174 SVSIKVGDEVGTGDLILKLKVEGAAPAAEEQPAAAPAQAAAPAAEQKPAAAAPAPAKADT 233
Query: 556 DAP-KTEQNQKIKVLTTPAVRRIAAQFKVDLSAVKATG 666
AP KV PAVR +A +F V+LS VKA+G
Sbjct: 234 PAPVGAPSRDGAKVHAGPAVRMLAREFGVELSEVKASG 271
>UniRef50_Q6ABX9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=5; Actinomycetales|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Leifsonia xyli
subsp. xyli
Length = 452
Score = 52.8 bits (121), Expect = 7e-06
Identities = 33/97 (34%), Positives = 48/97 (49%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ E I W V GD+V I E+++ K+ V + S ++G + L
Sbjct: 6 FLLPDVGEGLTEAEIVSWKVAPGDSVAVNQVIVEIETAKSLVELPSPFEGTVGELLVVEG 65
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDA 561
QT VG P+ V E D T+ A + A +DA
Sbjct: 66 QTVEVGTPI--FTVNGGEADHGVTEPAGEAEQAAVDA 100
>UniRef50_A4AGT3 Cluster: Putative dihydrolipoamide acyltransferase
component; n=1; marine actinobacterium PHSC20C1|Rep:
Putative dihydrolipoamide acyltransferase component -
marine actinobacterium PHSC20C1
Length = 480
Score = 52.4 bits (120), Expect = 1e-05
Identities = 29/75 (38%), Positives = 42/75 (56%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ E I EW V VGD V I EV++ KA V++ S G I+ L+ +
Sbjct: 6 FALPDLGEGLTESEIVEWHVAVGDMVTLNQPIAEVETAKAIVSLPSPVAGKISALHAEPG 65
Query: 451 QTALVGQPLVDIDVQ 495
T VG +V +++
Sbjct: 66 ATVSVGTRIVTFELE 80
>UniRef50_A4A156 Cluster: Pyruvate dehydrogenase, E2 component,
dihydrolipoamideacetyltransferase; n=2;
Planctomycetaceae|Rep: Pyruvate dehydrogenase, E2
component, dihydrolipoamideacetyltransferase -
Blastopirellula marina DSM 3645
Length = 472
Score = 52.4 bits (120), Expect = 1e-05
Identities = 33/100 (33%), Positives = 49/100 (49%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
KL ++G+GI I +V GD V + NI E+++DKA V I + G +T+++
Sbjct: 6 KLPELGDGIDSGDILSVYVSEGDVVTKNQNILELETDKATVEIPTNVAGKVTKVHVKTGD 65
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTE 573
+G L I V+ SE K P E +APK E
Sbjct: 66 AVPIGGAL--ISVEASEGAAKEESKPAPAPKKEAEAPKAE 103
>UniRef50_O00330 Cluster: Pyruvate dehydrogenase protein X
component, mitochondrial precursor; n=26; Amniota|Rep:
Pyruvate dehydrogenase protein X component,
mitochondrial precursor - Homo sapiens (Human)
Length = 501
Score = 52.4 bits (120), Expect = 1e-05
Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 18/164 (10%)
Frame = +1
Query: 229 RHFHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 405
R FH++ + + + + + E I +W K G+ V D +CE+++DKA VT+
Sbjct: 44 RWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLD 103
Query: 406 SRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGK----PTDVAPDKPVAEIDAPKTE 573
+ DGI+ ++ + + L+ + V++ E D K P DV P PV++ P+
Sbjct: 104 ASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGE-DWKHVEIPKDVGPPPPVSKPSEPRPS 162
Query: 574 QNQKIKV-------------LTTPAVRRIAAQFKVDLSAVKATG 666
+I + +PA R I + +D S ATG
Sbjct: 163 PEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATG 206
>UniRef50_Q2JA39 Cluster: Dehydrogenase subunit; n=4;
Actinomycetales|Rep: Dehydrogenase subunit - Frankia sp.
(strain CcI3)
Length = 430
Score = 52.0 bits (119), Expect = 1e-05
Identities = 25/76 (32%), Positives = 39/76 (51%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ + W V VGD + + EV++ KA V + Y G++T L
Sbjct: 7 FPLPDLGEGLTSAEVVRWLVGVGDVITVDQPVAEVETAKAVVEVPCPYAGVVTSLAGLAG 66
Query: 451 QTALVGQPLVDIDVQD 498
+ VG PL+ + V +
Sbjct: 67 TSVPVGTPLITVAVSE 82
>UniRef50_Q553V8 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Dictyostelium discoideum|Rep: Dihydrolipoamide
S-succinyltransferase - Dictyostelium discoideum AX4
Length = 439
Score = 52.0 bits (119), Expect = 1e-05
Identities = 40/166 (24%), Positives = 70/166 (42%), Gaps = 3/166 (1%)
Frame = +1
Query: 97 VRRSVFQLRTVNRCRKIKVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFK 276
V RS +L N ++ T S+ + + + + + + F++S N +V K
Sbjct: 21 VVRSTSRLINNNSINTVRQFTSSSSSSFTSLFNNNNVNNTNIKYQRFYSS--ANDVV-IK 77
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ +G+ I E I W VGD+V+ + +C +++DK + I + G I L+ +
Sbjct: 78 VPSMGDSISEGTIVAWTKNVGDSVRVDEVVCSIETDKVTIDINAPVSGTIVELFAKEGEN 137
Query: 457 ALVGQPLVDI---DVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQK 585
VG L I +V + P K A APK + K
Sbjct: 138 VTVGNDLYKIAKGEVAAAPKVEAPKAAEAPKAAAPTPAPKAAETPK 183
>UniRef50_A1SJ23 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=18; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 597
Score = 46.4 bits (105), Expect = 6e-04
Identities = 36/121 (29%), Positives = 53/121 (43%), Gaps = 5/121 (4%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
L +GE + E + W +VGD+V + + EV +DK I S G + + + D T
Sbjct: 7 LPALGESVTEGTVTRWLKQVGDSVAVDEPLLEVSTDKVDTEIPSPIAGTLLEIRANEDDT 66
Query: 457 ALVGQPLVDI-DVQDSEND--GKPTDVAPD-KPVAEID-APKTEQNQKIKVLTTPAVRRI 621
VG L I D +S D G + PD +P E P+ Q Q + PA +
Sbjct: 67 VEVGAVLAVIGDAGESSGDSGGAQAEAQPDPEPEPEAQPEPEPAQEQAQQEAQQPAAEQP 126
Query: 622 A 624
A
Sbjct: 127 A 127
Score = 41.9 bits (94), Expect(2) = 1e-05
Identities = 34/123 (27%), Positives = 50/123 (40%), Gaps = 3/123 (2%)
Frame = +1
Query: 268 AFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDI 447
A L +GE + E + W VGD V + + EV +DK I S G + +
Sbjct: 141 AVTLPALGESVTEGTVTRWLKSVGDEVAVDEPLLEVSTDKVDTEIPSPVAGTLLEIKVAE 200
Query: 448 DQTALVGQPLVDI---DVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRR 618
D+T VG L I +E+ +PT +P E P+ E + PA +
Sbjct: 201 DETVEVGAELAVIGSGQAAPAESKPEPTPEPEPEPTPE---PEPEPEAAPEPEPAPAPQE 257
Query: 619 IAA 627
AA
Sbjct: 258 QAA 260
Score = 29.5 bits (63), Expect(2) = 1e-05
Identities = 13/22 (59%), Positives = 17/22 (77%)
Frame = +1
Query: 601 TPAVRRIAAQFKVDLSAVKATG 666
TP VR++AAQ VDL++V TG
Sbjct: 291 TPLVRKMAAQHGVDLASVTGTG 312
>UniRef50_A6WD54 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=5; Actinomycetales|Rep: 2-oxoglutarate dehydrogenase
E2 component - Kineococcus radiotolerans SRS30216
Length = 618
Score = 51.6 bits (118), Expect = 2e-05
Identities = 29/93 (31%), Positives = 40/93 (43%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+GE + E + W VGD V+ + + EV +DK I S G + + D+TA V
Sbjct: 10 LGESVTEGTVTRWLKAVGDTVEVDEPLLEVSTDKVDTEIPSPVAGTLLEILVPEDETADV 69
Query: 466 GQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAP 564
G L I + G P P A DAP
Sbjct: 70 GADLARIGDPSEQGGGSPAPQEQPAPAAPQDAP 102
Score = 48.0 bits (109), Expect = 2e-04
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 3/119 (2%)
Frame = +1
Query: 268 AFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDI 447
A K+ +GE + E + W VGD+V+ + + EV +DK I S G + +
Sbjct: 139 AVKMPALGESVTEGTVTRWLKAVGDSVEVDEPLLEVSTDKVDTEIPSPVAGTLLEILVGE 198
Query: 448 DQTALVGQPLV---DIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVR 615
D+TA VG L D S P AP P E A + + + + A +
Sbjct: 199 DETADVGADLARIGDASAAPSPAPAAPAQEAPAAPQEESLADEVAERETARAQAESATQ 257
>UniRef50_A0M206 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=1; Gramella forsetii KT0803|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Gramella forsetii
(strain KT0803)
Length = 507
Score = 51.6 bits (118), Expect = 2e-05
Identities = 28/104 (26%), Positives = 54/104 (51%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ I EG+ + E VK GD++++ +I V+SDKA+V I S G + +
Sbjct: 6 KIPQIAEGVESATVTEVLVKEGDSIEKDQSIIAVESDKASVEIPSPQAGTVKSISVSEGD 65
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQK 585
VG +++++ D+E D P + ++ + ++ K E ++K
Sbjct: 66 EVEVGDVILELEEGDAEED--PEEDKEEESEKDNESEKDEDSEK 107
Score = 33.9 bits (74), Expect = 3.6
Identities = 21/64 (32%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
Frame = +1
Query: 487 DVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIK----VLTTPAVRRIAAQFKVDLSAV 654
D +DS+ D D +E D K + +K V P VRR A + VD+S V
Sbjct: 177 DKKDSKGKKSKKDQEDDSEDSEKDDSKDSEKEKTSRTEDVAAAPGVRRFARELGVDISEV 236
Query: 655 KATG 666
K +G
Sbjct: 237 KGSG 240
>UniRef50_A0LLM2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Syntrophobacter
fumaroxidans MPOB|Rep: Catalytic domain of components of
various dehydrogenase complexes - Syntrophobacter
fumaroxidans (strain DSM 10017 / MPOB)
Length = 443
Score = 51.6 bits (118), Expect = 2e-05
Identities = 38/143 (26%), Positives = 64/143 (44%), Gaps = 9/143 (6%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
V F+L D+GEGI E I E V VGD V + +++DKA + + G++ +
Sbjct: 3 VEFRLPDLGEGIHEGEIVEVLVSVGDRVLDGQPVMVIETDKATTEVPAPVSGVVKEIRVK 62
Query: 445 IDQTALVGQPLVDIDVQDSENDGKP--TDVAPDKPVAEIDAPKTEQNQKIKVLTT----- 603
+ VG L+ + + P DV+ +K ++AP + V +
Sbjct: 63 PGEVVKVGAVLMTFEAEGRAVAAAPPEKDVSREK-AGGLEAPPGGGETRPAVTASKEPPA 121
Query: 604 --PAVRRIAAQFKVDLSAVKATG 666
P+ RR+A + +DL V +G
Sbjct: 122 AAPSTRRLARELGIDLRQVAPSG 144
>UniRef50_Q7NLM9 Cluster: Gll1092 protein; n=1; Gloeobacter
violaceus|Rep: Gll1092 protein - Gloeobacter violaceus
Length = 384
Score = 51.2 bits (117), Expect = 2e-05
Identities = 31/126 (24%), Positives = 59/126 (46%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I K+ +GEG++EV+I + G+++++ + I +++DKA + + S Y+G+I
Sbjct: 3 ITEIKIPQLGEGLQEVLIDRLLKRSGEHIKRDEAIYVIETDKALMDVESPYEGVIQEWLV 62
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRI 621
+ + LVG P+ I E+ P + P K PK++ + P R
Sbjct: 63 EENDVVLVGSPVARIQT-IIEHSAAP-HLEPRKAEFPETKPKSQIAPSSSAVIPPRTRAY 120
Query: 622 AAQFKV 639
Q +
Sbjct: 121 CKQLGI 126
>UniRef50_Q67ME8 Cluster: Branched-chain alpha-keto acid
dehydrogenase E2; n=2; Bacilli|Rep: Branched-chain
alpha-keto acid dehydrogenase E2 - Symbiobacterium
thermophilum
Length = 459
Score = 51.2 bits (117), Expect = 2e-05
Identities = 41/140 (29%), Positives = 61/140 (43%), Gaps = 10/140 (7%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ +GE + E I W V GD V+++ I EV +DK I + DG I L T
Sbjct: 5 MPQLGESVTEGTINRWLVAPGDVVKRYQPIAEVITDKVNAEIPAPADGRILTLDVPEGST 64
Query: 457 ALVGQPLVDIDVQDSENDGKPTDV-----APDKPVAEIDAPKT-----EQNQKIKVLTTP 606
VG + ++V + P V A + A AP ++ + +P
Sbjct: 65 VPVGARIATMEVAGEDAGQAPAPVGASAQAASQAAAPQGAPAVGGGSGAPDRASRGRYSP 124
Query: 607 AVRRIAAQFKVDLSAVKATG 666
AV R+A + VDLS V+ TG
Sbjct: 125 AVLRLAQEHGVDLSQVRGTG 144
>UniRef50_Q1IIF0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=2; Acidobacteria|Rep: Dihydrolipoamide
S-succinyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 555
Score = 51.2 bits (117), Expect = 2e-05
Identities = 38/142 (26%), Positives = 63/142 (44%), Gaps = 12/142 (8%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ +GE I E I +W VGD VQ+ + + E+ +DK I + G+++ + T
Sbjct: 127 MPQMGESIFEGTITKWLKNVGDTVQRDEPLFEISTDKVDAEIPAPVAGVLSEIKVQAGAT 186
Query: 457 ALVGQPLVDIDVQDSENDGKPTDV--APDKPVAEIDAPKT-----EQNQKI-----KVLT 600
V + I + P AP P AP+ + ++I +V T
Sbjct: 187 VQVNTVVATIGGAAGASARAPQAAAPAPSAPAPAAPAPQAPAAAEPEEEEISASGDRVRT 246
Query: 601 TPAVRRIAAQFKVDLSAVKATG 666
+P VR++A + VDL V+ TG
Sbjct: 247 SPLVRKMAKEANVDLGKVRGTG 268
Score = 44.8 bits (101), Expect = 0.002
Identities = 28/96 (29%), Positives = 42/96 (43%), Gaps = 2/96 (2%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ +GE I E I +W + GD VQ+ + + E+ +DK I + GI+ + QT
Sbjct: 7 MPQMGESIFEGTITKWLKQPGDQVQRDEPLFEISTDKVDAEIPAPAAGILKEIKAQAGQT 66
Query: 457 ALVGQPLVDIDVQDSENDG--KPTDVAPDKPVAEID 558
V + ID S KP AP K + D
Sbjct: 67 VQVNTVVAIIDAAGSATTSAPKPAAAAPPKSAPQPD 102
>UniRef50_A6C4P4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzyme; n=1; Planctomyces maris DSM
8797|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzyme - Planctomyces maris DSM 8797
Length = 449
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/110 (29%), Positives = 54/110 (49%), Gaps = 5/110 (4%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL ++ EG+ + + V VGD V+Q + ++++DKA V + S Y G I L
Sbjct: 5 FKLPEVSEGVETADVGQISVAVGDTVEQGQVLMDIETDKAVVQLESPYSGTIEELKVSEG 64
Query: 451 QTALVGQPLVDI-----DVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQK 585
+ +G L+ I D + K + ++PVAE P+T Q ++
Sbjct: 65 DSVSIGAVLLLINESNGDASAPAKEEKSAETKAEEPVAE--EPETAQKEQ 112
>UniRef50_A5UU13 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=4; Bacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Roseiflexus sp. RS-1
Length = 459
Score = 51.2 bits (117), Expect = 2e-05
Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 12/139 (8%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+G ++E I W K GD V++ + I E+++DK + I + G +T + Q+A V
Sbjct: 9 MGFDMQEGTIVRWLKKPGDAVRRGEPIAEIETDKVTIEIEAFESGTLTEIVVQEGQSAPV 68
Query: 466 GQPLVDIDVQDSENDGKPTDVAP-----------DKPVAEIDAPKTEQNQKI-KVLTTPA 609
+ +D + P AP P+ E AP E I + +P
Sbjct: 69 NAVIARLDGGNGSQAPVPVAAAPAVPPPAEVSPPPAPLPETPAPLAEPPADIGDIRASPL 128
Query: 610 VRRIAAQFKVDLSAVKATG 666
RR+A ++ +DL V+ +G
Sbjct: 129 ARRLAREYGIDLRQVRGSG 147
>UniRef50_A4CQ51 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=13; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Robiginitalea biformata HTCC2501
Length = 476
Score = 51.2 bits (117), Expect = 2e-05
Identities = 24/91 (26%), Positives = 45/91 (49%), Gaps = 3/91 (3%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
KL +GE + E + W +VGD ++ + + E+ +DK + S DG++ ++D
Sbjct: 7 KLPQMGESVAEATLTSWLKEVGDAIEADEAVFEIATDKVDSEVPSEVDGVLVEKRFEVDD 66
Query: 454 TALVGQPLVDIDV---QDSENDGKPTDVAPD 537
VGQ + I++ D + G+ +PD
Sbjct: 67 VVKVGQVVAVIELNGESDQPDAGREAAGSPD 97
>UniRef50_A1UIB1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=4; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Mycobacterium sp. (strain KMS)
Length = 629
Score = 51.2 bits (117), Expect = 2e-05
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 5/109 (4%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
V+ ++ +GE + E + W + GD V+Q + + EV +DK I S G++ ++
Sbjct: 21 VSVQMPALGESVTEGTVTRWLKQEGDTVEQDEPLLEVSTDKVDTEIPSPASGVLQKIVAQ 80
Query: 445 IDQTALVGQPLVDI-----DVQDSENDGKPTDVAPDKPVAEIDAPKTEQ 576
D T VG L I D DS +D + ++P E ++ T +
Sbjct: 81 EDDTVEVGGELAVIGEGGEDSGDSSDDSSSDEDEDEEPAEEAESETTSE 129
Score = 51.2 bits (117), Expect = 2e-05
Identities = 32/119 (26%), Positives = 53/119 (44%), Gaps = 1/119 (0%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ ++GE + E + W KVGD+V+ + + EV +DK I S G + + + D T
Sbjct: 172 MPELGESVTEGTVTRWLKKVGDSVEVDEPLLEVSTDKVDTEIPSPVAGTLLEIIAEEDDT 231
Query: 457 ALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEID-APKTEQNQKIKVLTTPAVRRIAAQ 630
VG L I D +P +P E + P+ E Q+ K P ++ + Q
Sbjct: 232 VEVGGELAKIGDADQAEAEEPEPEPEPEPEPEPEPEPEPEPKQESKPEPKPEPKQESKQ 290
Score = 34.3 bits (75), Expect = 2.7
Identities = 21/58 (36%), Positives = 33/58 (56%)
Frame = +1
Query: 493 QDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQFKVDLSAVKATG 666
Q+S+ + KP +P + DA ++ + TP VR++AA+ VDL+AVK TG
Sbjct: 286 QESKQEAKPEPKKEPEP--QQDAEPSDGSGPY---VTPLVRKLAAEHDVDLAAVKGTG 338
>UniRef50_Q8DFQ0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase component;
n=17; Bacteria|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
component - Vibrio vulnificus
Length = 402
Score = 50.8 bits (116), Expect = 3e-05
Identities = 31/129 (24%), Positives = 63/129 (48%), Gaps = 1/129 (0%)
Frame = +1
Query: 283 DIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTAL 462
D+ E + + + W K GD V++ + + ++++DK + + + GI+ + + T L
Sbjct: 9 DLPESVADATVATWHKKPGDRVERDEVLVDIETDKVVLEVPASEAGILEAIVEEEGATVL 68
Query: 463 VGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQ-NQKIKVLTTPAVRRIAAQFKV 639
Q + I + + G+PT ++ D T +++ +PAVRR+ A+ +
Sbjct: 69 SKQLIGRIKL--AAVAGEPTADTTEESEPSPDKRHTASLSEESNDALSPAVRRLLAEHSL 126
Query: 640 DLSAVKATG 666
+ S VK TG
Sbjct: 127 EASQVKGTG 135
>UniRef50_Q7N5R0 Cluster: Similarities with dihydrolipoamide
acyltransferase and succinyltransferase; n=1;
Photorhabdus luminescens subsp. laumondii|Rep:
Similarities with dihydrolipoamide acyltransferase and
succinyltransferase - Photorhabdus luminescens subsp.
laumondii
Length = 521
Score = 50.8 bits (116), Expect = 3e-05
Identities = 32/109 (29%), Positives = 54/109 (49%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+GEG EVVI + +VGD+V++ + + E+++DKAA TI S +GI+ + + V
Sbjct: 9 MGEGTTEVVIIQLLKQVGDHVKRDEPVYEMETDKAAFTIESDVEGILEKWLAAENDIIPV 68
Query: 466 GQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAV 612
G P+ I + P A P +++ + + KV P V
Sbjct: 69 GSPIAVIRAVGEMAEPSPVSEALTPPPEKMERVAEDVEKIEKVEAAPEV 117
>UniRef50_UPI000023F136 Cluster: hypothetical protein FG10947.1;
n=1; Gibberella zeae PH-1|Rep: hypothetical protein
FG10947.1 - Gibberella zeae PH-1
Length = 442
Score = 50.4 bits (115), Expect = 4e-05
Identities = 31/124 (25%), Positives = 55/124 (44%)
Frame = +1
Query: 211 SLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKA 390
++ + R F S +N + + E I E + KVG+ V+Q + I +++DK
Sbjct: 37 AIDPQRRLFSNSGFLNGSYIVSVPPMAESITEGTLSSLSKKVGEAVEQDEEIASIETDKI 96
Query: 391 AVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKT 570
V + + G I + + T +VGQ L I + K ++ KP E PK
Sbjct: 97 DVLVNASEPGAIAEYFAEEGDTVVVGQDLARIVTGEDAGSAKKSEGGEQKPAKE--EPKK 154
Query: 571 EQNQ 582
E+++
Sbjct: 155 EESK 158
>UniRef50_A6Q8W6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase; n=1; Sulfurovum sp. NBC37-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Sulfurovum sp. (strain NBC37-1)
Length = 410
Score = 50.4 bits (115), Expect = 4e-05
Identities = 33/131 (25%), Positives = 59/131 (45%), Gaps = 2/131 (1%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FK+ +G + + EW VK G+ V++ I EV+S+K + + DG++ RL +
Sbjct: 4 FKMPSLGADMESGTLMEWKVKEGEKVKKGQVIAEVESNKGVIEVEVFEDGVVDRLLVEPG 63
Query: 451 QTALVGQPLVDI--DVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIA 624
T VG P+ I + + +E K K A + +TE +K P+ +
Sbjct: 64 TTCDVGTPIAVIVGENETAEALEKELGTQSGKEAAPKVSTETETTEKASEAKKPSKKESV 123
Query: 625 AQFKVDLSAVK 657
+ K ++ K
Sbjct: 124 KEAKTTVTKEK 134
>UniRef50_Q6KH64 Cluster: Pyruvate dehydrogenase E3 component
dihydrolipoamide dehydrogenase; n=2; Bacteria|Rep:
Pyruvate dehydrogenase E3 component dihydrolipoamide
dehydrogenase - Mycoplasma mobile
Length = 600
Score = 50.0 bits (114), Expect = 5e-05
Identities = 30/93 (32%), Positives = 48/93 (51%), Gaps = 2/93 (2%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FK +DIGEG+ E ++ E + K GD V++ + + V++DK I S G I ++
Sbjct: 4 FKFADIGEGLHEGLVAEIYKKEGDMVKEGEALFSVETDKVTSDIPSPATGKIVKVAMAQG 63
Query: 451 QTALVGQPLVDIDVQDSEN--DGKPTDVAPDKP 543
T VGQ + ID S + KP ++ + P
Sbjct: 64 DTIHVGQEIYYIDDGSSSQSIEVKPAEIKAEAP 96
>UniRef50_Q5P915 Cluster: Pyruvate dehydrogenase multienzyme
complex, dihydrolipoamide acetyltransferase component;
n=16; Proteobacteria|Rep: Pyruvate dehydrogenase
multienzyme complex, dihydrolipoamide acetyltransferase
component - Azoarcus sp. (strain EbN1) (Aromatoleum
aromaticum (strain EbN1))
Length = 583
Score = 50.0 bits (114), Expect = 5e-05
Identities = 24/89 (26%), Positives = 48/89 (53%)
Frame = +1
Query: 253 VNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR 432
+++++ K+ DIG+ +V + E FVK GD ++ D I ++SDKA + + S G++
Sbjct: 1 MSELIEVKVPDIGD-YADVPVIELFVKPGDTIKVEDPIATLESDKATMDVPSTAAGVVRE 59
Query: 433 LYHDIDQTALVGQPLVDIDVQDSENDGKP 519
+ + G+ L+ ++ +EN P
Sbjct: 60 VLVQVGDRVAEGKVLIKVEAAGAENTAAP 88
Score = 43.2 bits (97), Expect = 0.006
Identities = 22/72 (30%), Positives = 40/72 (55%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
++ DIG+ +V + E FVKVGD ++ D+I ++SDKA + + S G++ + +
Sbjct: 144 RVPDIGD-FSDVPVIELFVKVGDTIKVEDSIATLESDKATMDVPSSAAGVVREVKIKVGD 202
Query: 454 TALVGQPLVDID 489
G L+ +D
Sbjct: 203 RVSEGAVLIVVD 214
>UniRef50_A6EAZ4 Cluster: Dihydrolipoyllysine-residue
acetyltransferase; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue acetyltransferase -
Pedobacter sp. BAL39
Length = 549
Score = 50.0 bits (114), Expect = 5e-05
Identities = 43/149 (28%), Positives = 72/149 (48%), Gaps = 18/149 (12%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
+ ++ + + + E VI EW KVGD V+ D + +V++DKA + + +G T L+
Sbjct: 133 VTVVRMPLLSDTMTEGVIAEWHKKVGDQVKNDDILADVETDKATMEVMGYAEG--TLLHI 190
Query: 442 DIDQ---------TALVGQPLVDID--VQDSENDGKP-TDVAPDKPVAE-IDAPKTEQNQ 582
+++ A+VG DI + + KP D D PVAE +A K E+
Sbjct: 191 GVEKGAAAKVNGIIAIVGPEGTDISGILAQGDAPAKPAADKKSDAPVAEKTEAAKAEEVP 250
Query: 583 KI-----KVLTTPAVRRIAAQFKVDLSAV 654
K+ +V +P +RIA +DL+ V
Sbjct: 251 KVATGSDRVKASPLAKRIAKDKGIDLAEV 279
Score = 44.4 bits (100), Expect = 0.003
Identities = 35/116 (30%), Positives = 57/116 (49%), Gaps = 14/116 (12%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ + + + E V+ +W KVGD ++ D + EV++DKA + + S +DG T LY +++
Sbjct: 6 KMPKMSDTMTEGVMAKWHKKVGDKIKSGDVMAEVETDKATMDLESYWDG--TVLYIGVEE 63
Query: 454 ---------TALVGQPLVDIDVQ-DSENDGKPT--DVAPDKP--VAEIDAPKTEQN 579
A+VG+ D D+E P D DKP +APK E +
Sbjct: 64 GKAVPVDAIIAVVGKEGEDFQAAIDAEGGAAPAKEDKTADKPAEAKTEEAPKAESS 119
>UniRef50_A5EW59 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Dichelobacter nodosus VCS1703A|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Dichelobacter nodosus (strain
VCS1703A)
Length = 341
Score = 50.0 bits (114), Expect = 5e-05
Identities = 22/92 (23%), Positives = 49/92 (53%), Gaps = 1/92 (1%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ + E + + ++ W VGD V+Q +N+ ++++DK + + + GII + +
Sbjct: 6 KIPTLPESVSDAILVNWHKSVGDFVEQGENLIDLETDKVMLEMPAPVSGIIAEILQEDGM 65
Query: 454 TALVGQPLVDIDVQDSENDGKPT-DVAPDKPV 546
T + GQ + I+ Q +++ P + ++PV
Sbjct: 66 TVISGQVIARIEEQKQQHEVPPAKKITIEEPV 97
>UniRef50_Q5BXT9 Cluster: SJCHGC06137 protein; n=1; Schistosoma
japonicum|Rep: SJCHGC06137 protein - Schistosoma
japonicum (Blood fluke)
Length = 185
Score = 50.0 bits (114), Expect = 5e-05
Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 1/94 (1%)
Frame = +1
Query: 229 RHF-HTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 405
RHF HTS + V K+ + + + I W G++V D +CEVQ+DKA ++
Sbjct: 14 RHFIHTSRRIQFPVNIKMPSLSPTMSDGTIVNWLKNEGEDVTAGDVLCEVQTDKAVISFE 73
Query: 406 SRYDGIITRLYHDIDQTALVGQPLVDIDVQDSEN 507
S DG++ ++ +++ L+ + EN
Sbjct: 74 SDEDGVLAKILAPAGSSSIKVGGLIAVLATPGEN 107
>UniRef50_Q89AJ6 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=15; Proteobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Baizongia pistaciae
Length = 410
Score = 50.0 bits (114), Expect = 5e-05
Identities = 39/142 (27%), Positives = 69/142 (48%), Gaps = 7/142 (4%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I+ + D+ E + + I +W K GD VQ+ + ++++DK + I S DGI+ +
Sbjct: 3 IINIFIPDLPESVTDATIIKWHKKKGDKVQEDTILVDIETDKVILEIPSPSDGILNSIIA 62
Query: 442 DIDQTALVGQ---PLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLT---T 603
D + L GQ L+ I +++ E K T+ V D QN +K+L +
Sbjct: 63 DKGKIVLPGQVIGTLLKIGIKNEEKIIKTTN-----NVVNTD---NNQNINLKLLEKTYS 114
Query: 604 PAVRRIAAQFKV-DLSAVKATG 666
P VRR+ + + D+ ++ TG
Sbjct: 115 PTVRRLISMHDLRDVDIIQGTG 136
>UniRef50_Q83G30 Cluster: Dihydrolipoamide succinyltransferase
component E2; n=2; Tropheryma whipplei|Rep:
Dihydrolipoamide succinyltransferase component E2 -
Tropheryma whipplei (strain Twist) (Whipple's bacillus)
Length = 461
Score = 49.6 bits (113), Expect = 7e-05
Identities = 27/78 (34%), Positives = 38/78 (48%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L +GE + E VI W + GD V+ + + EV +DK + S GI+ + D
Sbjct: 5 FILPALGESVSECVITRWLKEAGDRVEVDEPLVEVSTDKVDTELPSTLTGILEEILVQRD 64
Query: 451 QTALVGQPLVDIDVQDSE 504
+TA GQ L I V E
Sbjct: 65 ETAKPGQILARIAVDKDE 82
>UniRef50_Q7X2B2 Cluster: PdhC; n=1; Lactobacillus reuteri|Rep: PdhC
- Lactobacillus reuteri
Length = 285
Score = 49.6 bits (113), Expect = 7e-05
Identities = 34/113 (30%), Positives = 51/113 (45%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F+L ++GEG+ E I + VK GD V+ D + E+Q+DK+ + S G I ++ D
Sbjct: 5 FRLPEMGEGLTEGDIASFLVKEGDQVKDGDPLVEIQTDKSTTQLVSPVAGTIKKIEAKED 64
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
G LV I D DG T+V + D E++ PA
Sbjct: 65 DHVEKGNDLVLI---DDGKDGVSTNVDAEDADDSADDTAAEESSAPAESEAPA 114
>UniRef50_A1T0M1 Cluster: Pyruvate dehydrogenase complex, E2
component dihydrolipoamide acetyltransferase; n=1;
Psychromonas ingrahamii 37|Rep: Pyruvate dehydrogenase
complex, E2 component dihydrolipoamide acetyltransferase
- Psychromonas ingrahamii (strain 37)
Length = 451
Score = 49.6 bits (113), Expect = 7e-05
Identities = 27/92 (29%), Positives = 49/92 (53%), Gaps = 2/92 (2%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ G +++ + +W VK GD++++ D + +++ K A+ + D +I L Q
Sbjct: 9 KMPSFGSDMKKGTLVQWLVKEGDHIKRGDVVAVIETHKGAIDLDLFEDALIISLLIKEGQ 68
Query: 454 TALVGQPLVDI-DVQDSENDGKP-TDVAPDKP 543
VG+P+ + +DSEN P TDVA +P
Sbjct: 69 QIAVGEPIARLSSTKDSENAPLPQTDVADIEP 100
>UniRef50_Q1EGH5 Cluster: Pyruvate dehydrogenase E2 subunit; n=3;
Nyctotherus ovalis|Rep: Pyruvate dehydrogenase E2
subunit - Nyctotherus ovalis
Length = 485
Score = 49.6 bits (113), Expect = 7e-05
Identities = 48/182 (26%), Positives = 87/182 (47%), Gaps = 17/182 (9%)
Frame = +1
Query: 172 NGSQLSYKT-PLNESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNV 348
N S L+ K+ P S + +S+ +K++ L ++ + + I +W+ K GD V
Sbjct: 28 NRSFLTVKSKPAQFPNSLGMARAFSSYPEHKVL--DLPNLSPTMTKGYITKWYKKEGDPV 85
Query: 349 QQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDIDVQDSENDGKPTD 525
D IC+V++DKA V DG+I + L + + +G+P V I V ++++ D
Sbjct: 86 TAGDVICDVETDKATVGYEMVEDGVIAKILMPEGSKEVPLGKP-VAIMVTEAKDVAAFKD 144
Query: 526 VAPD---KPVAE------------IDAPKTEQNQKIKVLTTPAVRRIAAQFKVDLSAVKA 660
P+ KP A+ +AP+ + + +V PA ++ A + +DLS V
Sbjct: 145 YKPEAAAKPAAKKEEAPKRETKSREEAPRESKRSEGRVRAAPAAKKFAEENNIDLSEVTG 204
Query: 661 TG 666
+G
Sbjct: 205 SG 206
>UniRef50_A7SJI4 Cluster: Predicted protein; n=2; Nematostella
vectensis|Rep: Predicted protein - Nematostella
vectensis
Length = 396
Score = 49.6 bits (113), Expect = 7e-05
Identities = 38/136 (27%), Positives = 65/136 (47%), Gaps = 18/136 (13%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I W K GD ++ D +CE+++DKA +T+ + G++ ++ + L+ + V
Sbjct: 13 IVSWLKKEGDTIEPGDALCEIETDKATLTLDTDEQGVLAKIVIPPGTKNVKVNELIALIV 72
Query: 493 QDSENDGK------------PTDVAPDKPV-----AEIDAPKTEQNQKIKVLT-TPAVRR 618
++ E+ K P DVAP AE +A + K +L+ +PAVR
Sbjct: 73 EEGEDYTKVVVPVTGNCVVIPFDVAPPHSAGTSDEAEDEAQSSATPHKGSLLSFSPAVRY 132
Query: 619 IAAQFKVDLSAVKATG 666
+ K+D SA+ ATG
Sbjct: 133 MLETNKIDSSAIPATG 148
>UniRef50_Q2UDD6 Cluster: Predicted protein; n=1; Aspergillus
oryzae|Rep: Predicted protein - Aspergillus oryzae
Length = 149
Score = 49.6 bits (113), Expect = 7e-05
Identities = 22/76 (28%), Positives = 44/76 (57%)
Frame = +1
Query: 289 GEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVG 468
GE I E ++ + KVGD V+Q D + ++++K A+ + + G+I +++ + T +G
Sbjct: 73 GESIDEAKLQSFNRKVGDYVKQDDVLAVIETEKVALEVYAPETGVIQQVFVEEGDTVTIG 132
Query: 469 QPLVDIDVQDSENDGK 516
Q + +I ++ DGK
Sbjct: 133 QAIAEITIKSKPGDGK 148
>UniRef50_O94709 Cluster: Probable pyruvate dehydrogenase protein X
component, mitochondrial precursor; n=1;
Schizosaccharomyces pombe|Rep: Probable pyruvate
dehydrogenase protein X component, mitochondrial
precursor - Schizosaccharomyces pombe (Fission yeast)
Length = 456
Score = 49.6 bits (113), Expect = 7e-05
Identities = 32/115 (27%), Positives = 64/115 (55%), Gaps = 1/115 (0%)
Frame = +1
Query: 211 SLSKELRHFHTSHAVNKIVA-FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDK 387
SLS + R+FH S A+N + + F++ + + E I +W K GD+ + D + EV++DK
Sbjct: 18 SLSVKQRYFHCS-ALNGVASMFRMPALSPTMEEGNITKWHFKEGDSFKSGDILLEVETDK 76
Query: 388 AAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE 552
A + + + +GI+ ++ + VG+ + V D+E++ K ++ D+ +E
Sbjct: 77 ATMDVEVQDNGILAKVLIEKGSNIPVGKNIA--IVADAEDNLKDLELPKDEASSE 129
>UniRef50_Q49110 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of pyruvate dehydrogenase
complex; n=3; Mollicutes|Rep:
Dihydrolipoyllysine-residue acetyltransferase component
of pyruvate dehydrogenase complex - Mycoplasma
capricolum subsp. capricolum (strain California kid /
ATCC27343 / NCTC 10154)
Length = 438
Score = 49.6 bits (113), Expect = 7e-05
Identities = 43/151 (28%), Positives = 66/151 (43%), Gaps = 20/151 (13%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K +DIGEG+ E + E VKVGD V++ ++ V++DK I + G I + Q
Sbjct: 5 KFADIGEGLTEGTVAEVLVKVGDVVKEGQSLYFVETDKVNSEIPAPVAGKIAVINIKAGQ 64
Query: 454 TALVGQPLVDI-DVQDSENDGKP----------------TDVAPDKPVAE---IDAPKTE 573
VG +++I D D+ +P V PV+ + T
Sbjct: 65 EIKVGDVVMEIEDGSDTSATSEPKAETKSEAKVEVVEENASVVGATPVSNDVIVRKQTTT 124
Query: 574 QNQKIKVLTTPAVRRIAAQFKVDLSAVKATG 666
N+ + TP R++AA +DLS V TG
Sbjct: 125 VNKSSTIKATPLARKVAADLNIDLSLVTPTG 155
>UniRef50_UPI000150A9DD Cluster: pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase family protein; n=1;
Tetrahymena thermophila SB210|Rep: pyruvate
dehydrogenase complex dihydrolipoamide acetyltransferase
family protein - Tetrahymena thermophila SB210
Length = 646
Score = 49.2 bits (112), Expect = 9e-05
Identities = 36/150 (24%), Positives = 73/150 (48%), Gaps = 7/150 (4%)
Frame = +1
Query: 148 KVTTQSARNGSQLSYKTPL------NESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREV 309
+ + + + G + S+K PL ++SLS+ + + +S+ +++VA L + + E
Sbjct: 38 RYSMSTVQKGKKTSFKAPLYQINFQSQSLSQNITYNFSSYPKHRLVA--LPALSPTMTEG 95
Query: 310 VIKEWFVKVGDNVQQFDNICEVQSDKAAV-TITSRYDGIITRLYHDIDQTALVGQPLVDI 486
I W +KVG +Q+ DNI +VQ+DK +V + G + ++ + + P+V +
Sbjct: 96 KIAAWHIKVGQKIQEGDNIFDVQTDKDSVPNVYQEETGFVAKILVNEGELIPANTPVVVV 155
Query: 487 DVQDSENDGKPTDVAPDKPVAEIDAPKTEQ 576
+++ A+ +APK EQ
Sbjct: 156 CKSEADIPAFANFTVGGAQKAQ-EAPKQEQ 184
Score = 34.7 bits (76), Expect = 2.1
Identities = 26/108 (24%), Positives = 46/108 (42%), Gaps = 1/108 (0%)
Frame = +1
Query: 160 QSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVG 339
Q A+ + P ++ +K + + K L + + E I + VKVG
Sbjct: 174 QKAQEAPKQEQPKPAAQTAAKPAPAASSGASFPKHNVVLLPALSPTMTEGKIASFHVKVG 233
Query: 340 DNVQQFDNICEVQSDKAAV-TITSRYDGIITRLYHDIDQTALVGQPLV 480
D V + DNI +VQ+DK +V I G + ++ +T P++
Sbjct: 234 DKVTEGDNIFDVQTDKDSVPNIYQEASGFVAKILVKEGETIPANHPVL 281
>UniRef50_Q820A3 Cluster: AceF; dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex (E2)
protein; n=1; Nitrosomonas europaea|Rep: AceF;
dihydrolipoamide acetyltransferase component of pyruvate
dehydrogenase complex (E2) protein - Nitrosomonas
europaea
Length = 453
Score = 49.2 bits (112), Expect = 9e-05
Identities = 29/96 (30%), Positives = 46/96 (47%)
Frame = +1
Query: 283 DIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTAL 462
DIG+ ++ + E VK GD+VQ D + ++SDKA V + S Y GII + +
Sbjct: 13 DIGD-FEDIPVIEIMVKPGDSVQVEDPLIVLESDKATVEVPSPYSGIIREIRVQMGSKVS 71
Query: 463 VGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKT 570
++ ++V +E+D K T P A T
Sbjct: 72 KDSEILTMEVVSAESDNKTTSSQPQPSAGSQPAQPT 107
Score = 35.1 bits (77), Expect = 1.6
Identities = 24/61 (39%), Positives = 30/61 (49%), Gaps = 4/61 (6%)
Frame = +1
Query: 496 DSENDGKP--TDVAPDKPVAEIDAPK--TEQNQKIKVLTTPAVRRIAAQFKVDLSAVKAT 663
+ E KP T P P A I P +Q+ KI +P+VRR A + VDLS V T
Sbjct: 118 EEEPAAKPAATTTKPATPSAPIQIPDHTIDQHNKIIPHASPSVRRFARELGVDLSKVVGT 177
Query: 664 G 666
G
Sbjct: 178 G 178
>UniRef50_Q4AFR6 Cluster: Biotin/lipoyl attachment; n=1; Chlorobium
phaeobacteroides BS1|Rep: Biotin/lipoyl attachment -
Chlorobium phaeobacteroides BS1
Length = 214
Score = 49.2 bits (112), Expect = 9e-05
Identities = 39/119 (32%), Positives = 57/119 (47%), Gaps = 3/119 (2%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
IV K+ GE I EV I W V G V ++I E+ SDKA +++ + +G IT L
Sbjct: 2 IVEIKVPTPGESITEVQIASWLVANGQQVTSDEDIVEIDSDKATLSVAAGAEGKITILAE 61
Query: 442 DIDQTALVGQPLVDID--VQDSENDGKPTDVAPDK-PVAEIDAPKTEQNQKIKVLTTPA 609
+ T V + ID VQ + + K T K P +I P T + +IK +P+
Sbjct: 62 E-GATVEVNSIIATIDTAVQGTIPEEKTTTAKVAKQPEEDIKTP-TSNDPEIKSQLSPS 118
>UniRef50_A6Q9K5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase; n=1; Sulfurovum sp. NBC37-1|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Sulfurovum sp. (strain NBC37-1)
Length = 446
Score = 49.2 bits (112), Expect = 9e-05
Identities = 40/136 (29%), Positives = 60/136 (44%), Gaps = 2/136 (1%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
K+V +LSD + E + EW ++ GD V+ D I EV+SDKA + I G + L
Sbjct: 4 KVVMPRLSD---SMDEGQLVEWKIRPGDVVRNGDVIAEVESDKAVMEIQIFKSGTVKELL 60
Query: 439 HDIDQTALVGQPLVDIDVQ-DSENDGKPTDVAPDKPVAEID-APKTEQNQKIKVLTTPAV 612
D T VG P+ ID S + K + + ++ + A K + +K PAV
Sbjct: 61 IDAGSTVPVGTPMAVIDTDVGSGSSVKTEEKSKEQNSTSVSAAQKPTETVPVKEKRPPAV 120
Query: 613 RRIAAQFKVDLSAVKA 660
A + S A
Sbjct: 121 ETKKAPVETQASVPSA 136
>UniRef50_A0M5Y1 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=7; Flavobacteria|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Gramella forsetii (strain KT0803)
Length = 438
Score = 49.2 bits (112), Expect = 9e-05
Identities = 35/108 (32%), Positives = 52/108 (48%), Gaps = 4/108 (3%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ GE I EV I +W V+ GD V++ + EV SDKA + + + GIIT + D
Sbjct: 6 KVPSPGESITEVEIAQWLVEDGDYVEKDQAVAEVDSDKATLELPAEASGIITFKAEEGD- 64
Query: 454 TALVGQP--LVDIDVQDSENDGKPTDV--APDKPVAEIDAPKTEQNQK 585
VG+ L+D + + DG D D A+ D E+ +K
Sbjct: 65 LVQVGEVVCLIDTEAEKPGGDGGSDDSEDKKDGKEAKEDDKSAEEEEK 112
>UniRef50_Q4QCG0 Cluster: Dihydrolipoamide acetyltransferaselike
protein; n=2; Leishmania|Rep: Dihydrolipoamide
acetyltransferaselike protein - Leishmania major
Length = 394
Score = 49.2 bits (112), Expect = 9e-05
Identities = 27/87 (31%), Positives = 49/87 (56%), Gaps = 3/87 (3%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD-GIITRLYHDIDQTALVGQPLVDID 489
+ EW K+G+ V++ D C +Q+DKA V T+ ++ G + ++Y Q+A V + + +
Sbjct: 29 VVEWKKKIGELVKESDVFCTIQTDKAVVDYTNTFESGYLAKIYCGNGQSAPVAKTIA-VM 87
Query: 490 VQDSENDGKPTDVAP--DKPVAEIDAP 564
V D+ + K + P + P AE +AP
Sbjct: 88 VSDAADVSKADEYTPEGEVPAAEAEAP 114
Score = 42.7 bits (96), Expect = 0.008
Identities = 23/79 (29%), Positives = 44/79 (55%), Gaps = 1/79 (1%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD-GIITRLYHDIDQTALVGQPLVDID 489
+ EW K+G+ V++ D C +Q+DKA V T+ ++ G + ++Y Q+A V + + +
Sbjct: 155 VVEWKKKIGELVKESDVFCTIQTDKAVVDYTNTFESGYLAKIYCGNGQSAPVAKTIA-VM 213
Query: 490 VQDSENDGKPTDVAPDKPV 546
V D+ + K + P+ V
Sbjct: 214 VSDAADVEKVANYYPEDAV 232
>UniRef50_A6SDP7 Cluster: Putative uncharacterized protein; n=1;
Botryotinia fuckeliana B05.10|Rep: Putative
uncharacterized protein - Botryotinia fuckeliana B05.10
Length = 370
Score = 49.2 bits (112), Expect = 9e-05
Identities = 23/80 (28%), Positives = 43/80 (53%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ ++ E I E +K+W ++GD V+Q + I +++DK V + + G I + +
Sbjct: 42 KVPEMAESISEGTLKQWSKQIGDFVEQDEEIATIETDKIDVAVNAPEAGTIKEFLANEED 101
Query: 454 TALVGQPLVDIDVQDSENDG 513
T VGQ LV +++ + G
Sbjct: 102 TVTVGQDLVRLELGGAPEGG 121
>UniRef50_Q9KES1 Cluster: Dihydrolipoamide S-acetyltransferase; n=1;
Bacillus halodurans|Rep: Dihydrolipoamide
S-acetyltransferase - Bacillus halodurans
Length = 436
Score = 48.8 bits (111), Expect = 1e-04
Identities = 34/133 (25%), Positives = 60/133 (45%), Gaps = 10/133 (7%)
Frame = +1
Query: 298 IREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPL 477
++E + +WF + GD V+ + + E+ +DK + + + +G + + Y+ D V +
Sbjct: 14 MQEGTLLQWFKEEGDRVEVGEPLFEIMTDKINIEVEAYEEGTLLKRYYGEDDEIPVNHVI 73
Query: 478 VDIDVQD----------SENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAA 627
I D SE TD A D + K + + V TPA RRIA
Sbjct: 74 GYIGTPDESVPTEPPGASEITASSTDEAGDHRTTAV--KKAPSSDRENVRATPAARRIAK 131
Query: 628 QFKVDLSAVKATG 666
+ ++DL V+ +G
Sbjct: 132 EKRIDLRQVEGSG 144
>UniRef50_Q057P2 Cluster: 2-oxoglutarate dehydrogenase E2 component;
n=1; Buchnera aphidicola str. Cc (Cinara cedri)|Rep:
2-oxoglutarate dehydrogenase E2 component - Buchnera
aphidicola subsp. Cinara cedri
Length = 398
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/128 (25%), Positives = 65/128 (50%), Gaps = 3/128 (2%)
Frame = +1
Query: 283 DIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTAL 462
++ E + ++ +W K+GD V++ + I E+++DK + I+S +GI+ I Q L
Sbjct: 11 NLPESVNHAIMLKWNKKIGDYVKEDEIIAEIETDKIILEISSPKNGIL------ISQNIL 64
Query: 463 VGQPLVD---IDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQF 633
VG+ + I +++N K + +K + K ++ L TP +RR+ +
Sbjct: 65 VGEKIKSQSVIGFINNKNIKKEKKIKNNKKTKK----KNVHSENSLFLFTPKMRRLILNY 120
Query: 634 KVDLSAVK 657
+D+S +K
Sbjct: 121 NIDISKIK 128
>UniRef50_A1SQB9 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=3; Actinomycetales|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Nocardioides sp. (strain BAA-499 / JS614)
Length = 474
Score = 48.8 bits (111), Expect = 1e-04
Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 2/98 (2%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
+KL D GEG+ E I +W V VGD V+ + E+++ K+ V + S Y G ++ +
Sbjct: 4 YKLPDPGEGLTEAEIVKWHVAVGDVVEINQVVVEIETAKSIVELPSPYAGEVSAILVAEG 63
Query: 451 QTALVGQPLVDI--DVQDSENDGKPTDVAPDKPVAEID 558
+ VG P++ I DV G + PV EID
Sbjct: 64 ELVPVGTPIIAIGDDVAAEPAAGAAPEARAAAPV-EID 100
>UniRef50_Q4Q822 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase,
putative; n=5; Trypanosomatidae|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase, putative - Leishmania major
Length = 389
Score = 48.8 bits (111), Expect = 1e-04
Identities = 29/103 (28%), Positives = 48/103 (46%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
++ + I E I + W KVGD V + + IC+++SDK V + + +G+IT++ +
Sbjct: 26 LSINVPTIAESISTGKVVNWTKKVGDAVAEDEVICQIESDKLNVDVRAPANGVITKINFE 85
Query: 445 IDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTE 573
VG L + P AP ++DAPK E
Sbjct: 86 EGADVEVGAQL-----STMKEGPAPAAAAPKAAEVKLDAPKAE 123
>UniRef50_Q6CF67 Cluster: Yarrowia lipolytica chromosome B of strain
CLIB122 of Yarrowia lipolytica; n=1; Yarrowia
lipolytica|Rep: Yarrowia lipolytica chromosome B of
strain CLIB122 of Yarrowia lipolytica - Yarrowia
lipolytica (Candida lipolytica)
Length = 410
Score = 48.8 bits (111), Expect = 1e-04
Identities = 38/127 (29%), Positives = 60/127 (47%), Gaps = 12/127 (9%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
R HT+ + + F + + + E I W VK GD D I E+++DKA + + +
Sbjct: 12 RLLHTTPRLYQASNFAMPAMSPTMTEGGIVSWKVKEGDEFSAGDVILEIETDKAQIDVEA 71
Query: 409 RYDGIITRLY-----HDI---DQTALVGQPLVDIDVQD----SENDGKPTDVAPDKPVAE 552
DG++ ++Y DI D A++ +P DI D E+DGKP K +
Sbjct: 72 ADDGVMAKIYKKDGDKDIQVGDTIAVIAEPGDDIKTIDIPAPVESDGKPAPKEEAKEEVK 131
Query: 553 IDAPKTE 573
+APK E
Sbjct: 132 -EAPKEE 137
>UniRef50_UPI00015B5B2E Cluster: PREDICTED: similar to
ENSANGP00000010144; n=1; Nasonia vitripennis|Rep:
PREDICTED: similar to ENSANGP00000010144 - Nasonia
vitripennis
Length = 483
Score = 48.4 bits (110), Expect = 2e-04
Identities = 42/175 (24%), Positives = 77/175 (44%)
Frame = +1
Query: 61 RVLSSFIAMSILVRRSVFQLRTVNRCRKIKVTTQSARNGSQLSYKTPLNESLSKELRHFH 240
R L + V R+++Q + R +V + +N K + +S S + R+
Sbjct: 14 RALRRLTLLQSKVVRTLYQGGPTSCVRAQRVLDRHVQNSQT---KPHVIQSWSIQSRYIQ 70
Query: 241 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 420
++ ++ ++ + + I E ++ W K GD V++ D +CE+++DK +V + S G
Sbjct: 71 STSSLWEMKDVVVPAFADSISEGDVR-WEKKEGDQVKEDDVLCEIETDKTSVPVPSPAAG 129
Query: 421 IITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQK 585
++ + T G L IDV G A + P AE APK + K
Sbjct: 130 VLKNILKKDGDTVTPGTKLCQIDV--GATGGAAPSKAAETPKAE--APKAPEPAK 180
>UniRef50_Q8AB01 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-keto acid dehydrogenase complex;
n=8; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-keto acid
dehydrogenase complex - Bacteroides thetaiotaomicron
Length = 456
Score = 48.4 bits (110), Expect = 2e-04
Identities = 28/96 (29%), Positives = 45/96 (46%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ +GE I E I W VKVGD +Q+ D + EV + K + I S G + +
Sbjct: 7 KMPKLGESITEGTIVSWSVKVGDVIQEDDVLFEVNTAKVSAEIPSPVAGKVVEILFKEGD 66
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDA 561
T VG + +D+ E + T + P ++ +A
Sbjct: 67 TVAVGTVVAVVDMGGEEASDEETASGKETPESKENA 102
>UniRef50_Q0RVL0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase; n=1; Rhodococcus sp. RHA1|Rep:
Dihydrolipoyllysine-residue succinyltransferase -
Rhodococcus sp. (strain RHA1)
Length = 422
Score = 48.4 bits (110), Expect = 2e-04
Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 17/148 (11%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
L +G ++ ++ EW K GD V + I +++DK + I + G++ D+DQ
Sbjct: 7 LPQLGVEMKSALLAEWVRKDGDEVDGGEVIAIIETDKVSYEIEAPTAGVL-HTAADVDQE 65
Query: 457 ALVGQPLVDIDVQDSE--NDGKPTDVAPDKPVA----------EIDAP-----KTEQNQK 585
VG L + E + TD PD P + ++ P E++
Sbjct: 66 YKVGARLGAVSASRKEYLAVARGTDTHPDPPTSGTETTVQPERRVEQPPASTAAAERSTN 125
Query: 586 IKVLTTPAVRRIAAQFKVDLSAVKATGR 669
VL TP RR+AA +D+S ++ +GR
Sbjct: 126 GIVLATPLARRVAADAGMDISTIEGSGR 153
>UniRef50_A1UBW5 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=11; Mycobacterium|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Mycobacterium sp. (strain KMS)
Length = 399
Score = 48.4 bits (110), Expect = 2e-04
Identities = 38/147 (25%), Positives = 63/147 (42%), Gaps = 15/147 (10%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F++ +G + E + +W VK GD V + + V++ KAAV + +G + RL
Sbjct: 4 FRMPALGSDMDEGTLDQWLVKPGDTVTRGQVVAVVETTKAAVEVECWQEGTVDRLLVPEG 63
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAP----DKPVAEIDAPK-----------TEQNQK 585
QT VG PL + + E P + PVA ++ P+ +
Sbjct: 64 QTVRVGTPLATL-LAPGETPAPTAPAVPRTMRESPVA-VERPEGAGRPAPAAGPAIATRP 121
Query: 586 IKVLTTPAVRRIAAQFKVDLSAVKATG 666
+ +PA RR+AA +D + TG
Sbjct: 122 HRRWVSPAARRVAATLDIDADTLTGTG 148
>UniRef50_A1FTV4 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Xanthomonadaceae|Rep:
Catalytic domain of components of various dehydrogenase
complexes - Stenotrophomonas maltophilia R551-3
Length = 546
Score = 48.4 bits (110), Expect = 2e-04
Identities = 20/55 (36%), Positives = 34/55 (61%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
F L D+GEG+ + I EWFVK GD ++ + + +++ KA V + S + G + +L
Sbjct: 91 FNLPDLGEGLPDATIVEWFVKEGDVIKLDEPLVSMETAKAVVEVPSPFSGTVLKL 145
>UniRef50_Q2B858 Cluster: Pyruvate dehydrogenase E2; n=1; Bacillus
sp. NRRL B-14911|Rep: Pyruvate dehydrogenase E2 -
Bacillus sp. NRRL B-14911
Length = 391
Score = 48.0 bits (109), Expect = 2e-04
Identities = 35/131 (26%), Positives = 62/131 (47%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
KL DIGEG+ E I + VK GD V+ + + EVQ+DK I + GI+ +
Sbjct: 4 KLHDIGEGMSEAEINCFLVKQGDFVRADEPLVEVQTDKMTAEIPAPRAGIVREFAVKPGE 63
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQF 633
T VG L+ ++ ++S A I+ Q ++L +P R++A +
Sbjct: 64 TVEVGAVLLLLEPENSRQ-------------AAIEEGSHAGKQAKRILASPYTRKLAREN 110
Query: 634 KVDLSAVKATG 666
+++ ++ +G
Sbjct: 111 DINIDDIEGSG 121
>UniRef50_A7BC27 Cluster: Putative uncharacterized protein; n=1;
Actinomyces odontolyticus ATCC 17982|Rep: Putative
uncharacterized protein - Actinomyces odontolyticus ATCC
17982
Length = 448
Score = 48.0 bits (109), Expect = 2e-04
Identities = 35/137 (25%), Positives = 60/137 (43%), Gaps = 11/137 (8%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD---- 444
+ +G + +I EW + GD V + +++DK+ + + S +G + +L +
Sbjct: 7 MPQLGNSVESCIIVEWMIAEGDTVSVDQTLASIETDKSTMEVPSTAEGTVLKLLWEEGDE 66
Query: 445 ---IDQTALVGQPLVDIDVQDSENDGKPTDV-APDKPVA---EIDAPKTEQNQKIKVLTT 603
D +VG+P DI D P + AP + VA E AP ++ +
Sbjct: 67 VPVKDPLIIVGEPGEDISGLVPGGDAAPAEADAPAEQVAAAPEAGAP-AFATERATGAVS 125
Query: 604 PAVRRIAAQFKVDLSAV 654
P R +AA VD SA+
Sbjct: 126 PRARALAASNGVDASAI 142
>UniRef50_Q68FJ5 Cluster: MGC86218 protein; n=3; Tetrapoda|Rep:
MGC86218 protein - Xenopus laevis (African clawed frog)
Length = 478
Score = 47.6 bits (108), Expect = 3e-04
Identities = 38/153 (24%), Positives = 70/153 (45%), Gaps = 6/153 (3%)
Frame = +1
Query: 226 LRHFHTSHAVNKIVAFKLS--DIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVT 399
LR HT+ + + ++S + + E I +W K G++V D +CE+++DKA VT
Sbjct: 29 LRALHTAGTLRGVPGVQVSMPALSPTMEEGNIVKWLKKEGESVSAGDALCEIETDKAVVT 88
Query: 400 ITSRYDGIITR-LYHDIDQTALVGQ--PLVDIDVQDSENDGKPT-DVAPDKPVAEIDAPK 567
+ S DG++ + L + + +G L+ + QD + P+ V+P A
Sbjct: 89 MESNDDGVLAKILVEEGSKNVRLGSLIALLVEEGQDWKQVHVPSVKVSPTTVAAATKIAN 148
Query: 568 TEQNQKIKVLTTPAVRRIAAQFKVDLSAVKATG 666
K + +PA R I +D ++ +G
Sbjct: 149 VAPVAKRGLRMSPAARHIIDTHGLDTGSITPSG 181
>UniRef50_Q6KH63 Cluster: Pyruvate dehydrogenase E2 component
dihydrolipoamide acetyltransferase; n=6; Mycoplasma|Rep:
Pyruvate dehydrogenase E2 component dihydrolipoamide
acetyltransferase - Mycoplasma mobile
Length = 453
Score = 47.6 bits (108), Expect = 3e-04
Identities = 28/91 (30%), Positives = 45/91 (49%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FK +DIGEG+ E V+ E + K GD V++ + + V++DK I S G I ++
Sbjct: 4 FKFADIGEGLHEGVVAEIYKKEGDMVKEGEALFSVETDKVTSDIPSPVTGKIIKVAMFKG 63
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKP 543
T VGQ + I +D + + + P
Sbjct: 64 DTIHVGQEIYQI--EDGSSSSSSVGIKTEAP 92
>UniRef50_Q5ZVD7 Cluster: Pyruvate dehydrogenase E2 component; n=5;
Legionellales|Rep: Pyruvate dehydrogenase E2 component -
Legionella pneumophila subsp. pneumophila (strain
Philadelphia 1 /ATCC 33152 / DSM 7513)
Length = 550
Score = 47.6 bits (108), Expect = 3e-04
Identities = 39/156 (25%), Positives = 73/156 (46%), Gaps = 18/156 (11%)
Frame = +1
Query: 256 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
+K + + DIG G +V + + VK G V++ + ++ DKA + I S Y G + +
Sbjct: 126 SKDIEISIPDIG-GANDVDVIDILVKPGMEVEKDQALITLEGDKATMDIPSPYAGKVIEM 184
Query: 436 YHDIDQTALVGQPLV-----------DIDVQDSENDGKPTDVAPDKPVAEIDAP------ 564
+ G P++ +I+ +N + + +KP E+ +
Sbjct: 185 KIKLGDKVSQGTPILTLKTLGKSETPEIEKSQIKNISEQSIKEIEKPYEELKSEAISINN 244
Query: 565 -KTEQNQKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
+ +++ I + PAVRR+A +F VDLS V+ +GR
Sbjct: 245 LEIAESKSILISAGPAVRRLAREFGVDLSLVQGSGR 280
>UniRef50_Q59RQ7 Cluster: Putative uncharacterized protein; n=1;
Candida albicans|Rep: Putative uncharacterized protein -
Candida albicans (Yeast)
Length = 225
Score = 47.6 bits (108), Expect = 3e-04
Identities = 32/107 (29%), Positives = 54/107 (50%)
Frame = -1
Query: 539 LSGATSVGFPSFSESCTSISTRGCPTRAV*SISWYSRVMIPSYRLVMVTAALSLCTSQML 360
L+GA+ P S +SI PT V S S + V++P + T+ LS+ ++
Sbjct: 121 LAGASDADAPPAGASPSSILMISWPTSTVASTSTKNSVIVPDTGALTSTSILSVSMVAIV 180
Query: 359 SNC*TLSPTLTNHSLMTTSRIPSPISESLKATILLTA*LVWKCLNSL 219
S+ T SPT SL+ +++PS I ++ T+ T+ +WK N +
Sbjct: 181 SSWSTKSPT----SLLKAAKVPSVIDSAISGTLTETSAYLWKVKNGV 223
>UniRef50_Q8RBW8 Cluster: Dihydrolipoamide acyltransferases; n=1;
Thermoanaerobacter tengcongensis|Rep: Dihydrolipoamide
acyltransferases - Thermoanaerobacter tengcongensis
Length = 399
Score = 47.2 bits (107), Expect = 4e-04
Identities = 39/143 (27%), Positives = 62/143 (43%), Gaps = 16/143 (11%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+ GI V+ WF G VQ + + EVQ +KAA+ + + GI+T++ V
Sbjct: 11 VSNGIEGFVVN-WFKDEGQPVQAGELLLEVQFEKAAIELQAPVSGILTKILCPQGHVVKV 69
Query: 466 GQPLVDIDVQDSENDG------KPTDVAPDKPVAEIDAPKTEQNQKI----------KVL 597
GQ L I+ + +E G P + P + +T Q+ + V
Sbjct: 70 GQLLCLIEEKSTEVAGGSGSAVPPVHAPEETPHFHGETERTTQSTPVDSQVHSSNTGDVR 129
Query: 598 TTPAVRRIAAQFKVDLSAVKATG 666
TPA R++A + + L AV TG
Sbjct: 130 ATPAARKLARELGIPLEAVPGTG 152
>UniRef50_A6W003 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Marinomonas|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Marinomonas sp. MWYL1
Length = 414
Score = 47.2 bits (107), Expect = 4e-04
Identities = 29/128 (22%), Positives = 62/128 (48%), Gaps = 8/128 (6%)
Frame = +1
Query: 310 VIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY----HDIDQTALVGQ-- 471
V W V+ GD+V++ D I E+++DK ++ + + DG I ++ ++D+ ++G
Sbjct: 20 VFSTWLVEEGDHVRKGDPILELETDKVSMEVCAENDGFIGKILATSGDNVDEKTILGYLN 79
Query: 472 --PLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQFKVDL 645
++D + P K +A + K + L PAVR++ + ++L
Sbjct: 80 CGEQSEVDKASVDKSSSPVANDASKNIAVAKCGVADDGSK-RHLIGPAVRKLLRKHNLNL 138
Query: 646 SAVKATGR 669
S++ +G+
Sbjct: 139 SSIDGSGK 146
>UniRef50_A3VK82 Cluster: Putative uncharacterized protein; n=1;
Rhodobacterales bacterium HTCC2654|Rep: Putative
uncharacterized protein - Rhodobacterales bacterium
HTCC2654
Length = 472
Score = 47.2 bits (107), Expect = 4e-04
Identities = 42/150 (28%), Positives = 66/150 (44%), Gaps = 14/150 (9%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I L G + E + W + GD+ ++ + +V++DK + G + R+
Sbjct: 4 ITPITLPKWGLEMSEGTVTGWHLAEGDSAEKGAELVDVETDKIVNVVELDQAGTLRRIVV 63
Query: 442 DIDQTALVGQPLV---DIDVQDSENDG-----KPTDVA----PDKPVA--EIDAPKTEQN 579
+T VG + D V D+ DG KP D + D P A + +AP E
Sbjct: 64 PEGETVPVGTLIAVFADASVDDAAIDGFIADYKPVDASFEPGADAPAAPAKAEAPAPEPA 123
Query: 580 QKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
+ +K TP RR A VDL++V+ TGR
Sbjct: 124 KDVKA--TPLARRAAEAGGVDLASVEGTGR 151
>UniRef50_UPI0000ECB9E1 Cluster: Apoptosis inhibitor 5 (API-5).;
n=3; Amniota|Rep: Apoptosis inhibitor 5 (API-5). -
Gallus gallus
Length = 458
Score = 46.8 bits (106), Expect = 5e-04
Identities = 36/136 (26%), Positives = 61/136 (44%), Gaps = 18/136 (13%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY-----HDIDQTALVG--- 468
I +W K G+ V D +CE+++DKA VT+ S DGI+ ++ ++ +L+G
Sbjct: 67 IVKWLKKEGEMVNAGDALCEIETDKAVVTMESSDDGILAKILVEEGSKNVRLGSLIGLLV 126
Query: 469 -------QPLVDIDVQDSENDGKPTDVAPDKPVA-EIDAPKTEQNQ--KIKVLTTPAVRR 618
Q + D D + P P + AP ++Q K++ +PA R
Sbjct: 127 EEGQDWKQVEIPADANDQSSLAPPAAAVTSTPAGPSVSAPPKVEHQPGKLQFRLSPAARN 186
Query: 619 IAAQFKVDLSAVKATG 666
I +D S+V +G
Sbjct: 187 IVETHGLDPSSVTPSG 202
>UniRef50_Q8D6Q5 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase component;
n=13; Vibrionaceae|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
component - Vibrio vulnificus
Length = 381
Score = 46.8 bits (106), Expect = 5e-04
Identities = 32/109 (29%), Positives = 53/109 (48%), Gaps = 1/109 (0%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F L D+GEG+ E I +W V VGD V+ I V++ KA V + + + G I + +
Sbjct: 4 FILPDLGEGLAESEIIKWHVSVGDKVEVDQVILTVETAKATVDVPAPWAGTIITRHGNEG 63
Query: 451 QTALVGQPLVDIDVQD-SENDGKPTDVAPDKPVAEIDAPKTEQNQKIKV 594
+G L++I+ D +EN + D A + + Q ++KV
Sbjct: 64 DVVNIGALLLEIEDGDVTENSDQKVQQRED--AATVVGHVSNQMHQVKV 110
>UniRef50_Q7WED2 Cluster: Probable 2-oxo acid dehydrogenases
acyltransferase; n=2; Bacteria|Rep: Probable 2-oxo acid
dehydrogenases acyltransferase - Bordetella
bronchiseptica (Alcaligenes bronchisepticus)
Length = 416
Score = 46.8 bits (106), Expect = 5e-04
Identities = 37/133 (27%), Positives = 61/133 (45%), Gaps = 6/133 (4%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+G + E ++ EW V G V+ D++ V++DK A I ++ DG + + +T V
Sbjct: 12 LGLTMTEGMLIEWSVTSGAEVKAGDSLFVVETDKVANEIVAQADGTLAEILVAAGETVPV 71
Query: 466 GQPLV----DIDVQDSENDGKPTDV-APDKPVAE-IDAPKTEQNQKIKVLTTPAVRRIAA 627
G + D D P P +P AE A E + +V+ TP RR+A
Sbjct: 72 GTVVARWTGPGQGADDLADAPPAPAPQPPQPAAEAAPAAAREPARGGRVVATPLARRLAR 131
Query: 628 QFKVDLSAVKATG 666
+ +DL+ V +G
Sbjct: 132 EAGLDLAQVSGSG 144
>UniRef50_Q39RZ0 Cluster: Dihydrolipoamide succinyltransferase; n=3;
Geobacter|Rep: Dihydrolipoamide succinyltransferase -
Geobacter metallireducens (strain GS-15 / ATCC 53774 /
DSM 7210)
Length = 418
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/93 (25%), Positives = 49/93 (52%), Gaps = 3/93 (3%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ +GE + E ++ +W K G+ V++ + +CE+++DK + I + DG++T + +
Sbjct: 4 KVPSVGESVYEALVGKWLKKNGEAVRKDEPVCEIETDKITMEIDAGADGVLTIMVPE-GA 62
Query: 454 TALVGQPLVDIDVQDSE---NDGKPTDVAPDKP 543
T +G + I+ + GK +V P P
Sbjct: 63 TVKIGSVIGIIEAGTGDRGPGTGKGKEVPPLSP 95
>UniRef50_A2TU26 Cluster: Lipoamide acyltransferase component of
branched-chain alpha-ketoacid dehydrogenase complex;
n=4; Bacteroidetes|Rep: Lipoamide acyltransferase
component of branched-chain alpha-ketoacid dehydrogenase
complex - Dokdonia donghaensis MED134
Length = 439
Score = 46.8 bits (106), Expect = 5e-04
Identities = 31/123 (25%), Positives = 57/123 (46%), Gaps = 2/123 (1%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+GE I E I W V G++ ++ D + E+ +DK + + G++ + +D + V
Sbjct: 19 MGESITEGTIINWLVAEGESFEEGDILVEIATDKVDNEVPATSAGVMQKHLYDANAVVAV 78
Query: 466 GQPLVDIDVQ--DSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQFKV 639
G+P+ Q D+E P++ +P + PK + K+ PA R I + V
Sbjct: 79 GEPIATYLAQGGDAEKAINPSEKKEAQP-TKAQTPKKQAKPKV----APATRAIVSNENV 133
Query: 640 DLS 648
+S
Sbjct: 134 FVS 136
>UniRef50_Q38C09 Cluster: Dihydrolipoamide acetyltransferase,
putative; n=1; Trypanosoma brucei|Rep: Dihydrolipoamide
acetyltransferase, putative - Trypanosoma brucei
Length = 260
Score = 46.8 bits (106), Expect = 5e-04
Identities = 24/73 (32%), Positives = 42/73 (57%), Gaps = 1/73 (1%)
Frame = +1
Query: 310 VIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD-GIITRLYHDIDQTALVGQPLVDI 486
+I EW KVGD V++ D C +Q+DKA V T+ +D G + +++ +T V + +
Sbjct: 27 IIVEWKKKVGDLVKENDVFCTIQTDKAVVDFTNTFDAGYLGKIFRQNGETVAVASTIAAM 86
Query: 487 DVQDSENDGKPTD 525
V++S++ K D
Sbjct: 87 -VEESQDVAKLAD 98
>UniRef50_Q0LND0 Cluster: Dihydrolipoamide S-succinyltransferase;
n=1; Herpetosiphon aurantiacus ATCC 23779|Rep:
Dihydrolipoamide S-succinyltransferase - Herpetosiphon
aurantiacus ATCC 23779
Length = 442
Score = 46.4 bits (105), Expect = 6e-04
Identities = 38/156 (24%), Positives = 66/156 (42%), Gaps = 25/156 (16%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
++ +G + E + +W K GD V + + I EV++DK + I + G I + + +
Sbjct: 6 EMPKMGYDMVEGTLAKWLKKPGDEVSRGEPIAEVETDKVTIEIEAFEAGTILKFLVNEGE 65
Query: 454 TALVGQPLVDIDVQDSEND-----------------GKPTDVAPDKPVAEIDAPKTEQNQ 582
T VG P+ +ID +++ G+ + AP P K E
Sbjct: 66 TVPVGAPIAEIDDGSGDDEAEAANASVTPSSDAPAVGEGGEAAPPAPAVVAQPEKVEATP 125
Query: 583 KI--------KVLTTPAVRRIAAQFKVDLSAVKATG 666
++ TPA R +A Q VDL+ +K +G
Sbjct: 126 AASAPATSTGRLFATPAARGLAEQRGVDLAGLKGSG 161
>UniRef50_A6X6G3 Cluster: Biotin/lipoyl attachment domain protein;
n=1; Ochrobactrum anthropi ATCC 49188|Rep: Biotin/lipoyl
attachment domain protein - Ochrobactrum anthropi
(strain ATCC 49188 / DSM 6882 / NCTC 12168)
Length = 443
Score = 46.4 bits (105), Expect = 6e-04
Identities = 37/134 (27%), Positives = 60/134 (44%), Gaps = 16/134 (11%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I W+ K GD V + + E+++DKAA+ + + GII + VGQ + I
Sbjct: 19 ISRWYAKDGDTVTKGQLLFEIETDKAAMEVDAPASGIIADISAAEGTVVPVGQTVAWIYD 78
Query: 493 QDSENDGK-------PTDVAPDKPVAEIDA-----PKTEQNQK----IKVLTTPAVRRIA 624
+ E K P P + + E A PK+ Q+ K V TP RR+A
Sbjct: 79 EGEERSAKSAPVVEEPIVAVPVETIIETVAPNPVEPKSSQDDKNGSADDVRATPLARRLA 138
Query: 625 AQFKVDLSAVKATG 666
+ +DL+ ++ +G
Sbjct: 139 REAGIDLATIQGSG 152
>UniRef50_A5CEI9 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=1;
Orientia tsutsugamushi Boryong|Rep: 2-oxoglutarate
dehydrogenase, E2 component, dihydrolipoamide
succinyltransferase - Orientia tsutsugamushi (strain
Boryong) (Rickettsia tsutsugamushi)
Length = 425
Score = 46.4 bits (105), Expect = 6e-04
Identities = 36/139 (25%), Positives = 62/139 (44%), Gaps = 1/139 (0%)
Frame = +1
Query: 256 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
NK L +GE + I +W K GD V + I EV+SDK + I + G IT++
Sbjct: 5 NKETNIVLPSLGESVSTGTISKWHKKEGDIVALDEKIVEVESDKVGIDINANVPGKITKI 64
Query: 436 YHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKV-LTTPAV 612
+ VG+ + I +D ++ K +EID + I +PAV
Sbjct: 65 LKNEGDNVEVGEVICVI-----RSDVLQKEIHSSKS-SEIDINLSICEDIISANKLSPAV 118
Query: 613 RRIAAQFKVDLSAVKATGR 669
++ A+ K++ + +G+
Sbjct: 119 AKMVAEHKINPENISGSGK 137
>UniRef50_A4BP63 Cluster: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase; n=4;
Bacteria|Rep: 2-oxoglutarate dehydrogenase, E2
component, dihydrolipoamide succinyltransferase -
Nitrococcus mobilis Nb-231
Length = 443
Score = 46.4 bits (105), Expect = 6e-04
Identities = 31/150 (20%), Positives = 68/150 (45%), Gaps = 15/150 (10%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
+ K+ + E + E + W K GD V + +N+ ++++DK + + + DG++ ++ D
Sbjct: 3 IEVKVPALPESVTEATVVGWHKKPGDRVARDENLVDLETDKVVLEVPAPEDGVLGKILKD 62
Query: 445 IDQTALVGQPLVDIDVQDS------------ENDGK---PTDVAPDKPVAEIDAPKTEQN 579
T + + L ++ ++ E+D + PT A + +
Sbjct: 63 EGATVVADEVLACLEQGETNSQAERPASAKGEDDNRAPGPTSRQGSDDAARDRTAEPDAT 122
Query: 580 QKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
+PAVRR+ A+ ++D + ++ TGR
Sbjct: 123 PHRNDNLSPAVRRMVAEHELDPARIEGTGR 152
>UniRef50_A0Z3Y6 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, dihydrolipoamide acyltransferase (E2)
component, and related enzyme; n=1; marine gamma
proteobacterium HTCC2080|Rep: Pyruvate/2-oxoglutarate
dehydrogenase complex, dihydrolipoamide acyltransferase
(E2) component, and related enzyme - marine gamma
proteobacterium HTCC2080
Length = 388
Score = 46.4 bits (105), Expect = 6e-04
Identities = 40/132 (30%), Positives = 57/132 (43%), Gaps = 10/132 (7%)
Frame = +1
Query: 304 EVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVD 483
E I W GD V + D + E++SDK + DG++ R+ + VG L
Sbjct: 18 EGTITTWNKSQGDAVAKGDEVFEMESDKIVNVWEAPVDGVLRRVLAEPGDAHPVGALLGV 77
Query: 484 ID---VQDSEND-------GKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQF 633
I V D + D G AP + AE P Q ++P+VR++A +
Sbjct: 78 IAPAAVSDGDIDTFIAGYAGDDAKEAPAQATAEPAKP-VAQTSDAYTRSSPSVRKLADEL 136
Query: 634 KVDLSAVKATGR 669
VDLS V TGR
Sbjct: 137 NVDLSTVTGTGR 148
>UniRef50_P57389 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Enterobacteriaceae|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Buchnera aphidicola subsp. Acyrthosiphon pisum
(Acyrthosiphon pisumsymbiotic bacterium)
Length = 420
Score = 46.4 bits (105), Expect = 6e-04
Identities = 21/77 (27%), Positives = 41/77 (53%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
K + + D+ E I + + +W K+GD V DNI ++++DK + ++S DGI+ +
Sbjct: 2 KKINILVPDLPESISDATVVKWHKKIGDTVHCDDNIVDIETDKVMLEVSSPCDGILQSIL 61
Query: 439 HDIDQTALVGQPLVDID 489
+ + Q L +I+
Sbjct: 62 EKEGKVVISQQTLGEIN 78
>UniRef50_Q9FC63 Cluster: Putative acyltransferase; n=1;
Streptomyces coelicolor|Rep: Putative acyltransferase -
Streptomyces coelicolor
Length = 417
Score = 46.0 bits (104), Expect = 8e-04
Identities = 30/100 (30%), Positives = 44/100 (44%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
V+ L +GE + E + W +VGD V+ + + EV +DK I S G++ +
Sbjct: 3 VSVTLPALGESVTEGTVTRWLKQVGDRVEADEPLLEVSTDKVDTEIPSPAAGVLLEILAA 62
Query: 445 IDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAP 564
D+T VG L I D+ AP P A AP
Sbjct: 63 EDETVEVGAGLGIIGAPDT------APAAPAAPAAPAPAP 96
>UniRef50_Q1Q664 Cluster: Similar to 2-oxoglutarate dehydrogenase
complex E2 component; n=1; Candidatus Kuenenia
stuttgartiensis|Rep: Similar to 2-oxoglutarate
dehydrogenase complex E2 component - Candidatus Kuenenia
stuttgartiensis
Length = 416
Score = 46.0 bits (104), Expect = 8e-04
Identities = 31/135 (22%), Positives = 66/135 (48%), Gaps = 5/135 (3%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
+ +GE + E I +W V GD V++ + E+ +DK I S GII ++ + +
Sbjct: 7 MPQMGESVAEGTILKWLVNEGDYVEKEQPLVEISTDKIDTEIPSPSAGIIKKILY--KEG 64
Query: 457 ALVGQPLVDIDVQDSENDGKPTDVAPDKPVAE-IDAPKTE----QNQKIKVLTTPAVRRI 621
A++ V +++ E + V ++ E I+ +T + + + +P V+++
Sbjct: 65 AVLAVQTVIAQIEEGEIKAQAGTVKKEQEEKERIEISETAAIAGEREMHEKRYSPLVKKL 124
Query: 622 AAQFKVDLSAVKATG 666
A ++ V L+ +K +G
Sbjct: 125 AKEYNVSLTEIKGSG 139
>UniRef50_A6DL93 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Lentisphaera araneosa HTCC2155|Rep: Dihydrolipoamide
acetyltransferase - Lentisphaera araneosa HTCC2155
Length = 415
Score = 46.0 bits (104), Expect = 8e-04
Identities = 33/128 (25%), Positives = 65/128 (50%), Gaps = 1/128 (0%)
Frame = +1
Query: 289 GEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVG 468
GE + E I WF + G+ ++ + + E+++DKA++TIT+ G + + + D+T VG
Sbjct: 11 GESVTEADIARWFKEDGEFLELDEPMVELETDKASLTITAPAAGTL-HIKVEEDETVQVG 69
Query: 469 QPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKV-LTTPAVRRIAAQFKVDL 645
+ + ++ E G + AE++ + E V + +PA R++ A+ +
Sbjct: 70 EVIAVLE----EGVGSAAE-----STAEVEETEEEVEAAPSVDMASPAARKLIAENNISA 120
Query: 646 SAVKATGR 669
V ATG+
Sbjct: 121 QDVVATGK 128
>UniRef50_Q1EGH6 Cluster: Pyruvate dehydrogenase E2 subunit; n=1;
Euplotes sp. BB-2004|Rep: Pyruvate dehydrogenase E2
subunit - Euplotes sp. BB-2004
Length = 459
Score = 46.0 bits (104), Expect = 8e-04
Identities = 26/87 (29%), Positives = 41/87 (47%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
+ +W KVGD V+ D + EV++DKA V + DG + +L + + LV I V
Sbjct: 57 LAKWCKKVGDQVEPGDILAEVETDKATVDFEMQEDGYVAKLLVEEGAQDIALGELVAISV 116
Query: 493 QDSENDGKPTDVAPDKPVAEIDAPKTE 573
+D ++ D P+ AP E
Sbjct: 117 EDEDDVAAFKDYKPESTSEASQAPVKE 143
>UniRef50_O31550 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system;
n=13; Bacillus|Rep: Dihydrolipoyllysine-residue
acetyltransferase component of acetoin cleaving system -
Bacillus subtilis
Length = 398
Score = 46.0 bits (104), Expect = 8e-04
Identities = 33/134 (24%), Positives = 64/134 (47%), Gaps = 7/134 (5%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+G +++ + W KVGD V++ ++I +QS+K + I + G + + +
Sbjct: 10 LGMAMKQGEVSIWNKKVGDPVEKGESIASIQSEKIEMEIEAPEKGTLIDIKVKEGEEVPP 69
Query: 466 GQPLVDI-DVQDSENDGKPTDVAPD------KPVAEIDAPKTEQNQKIKVLTTPAVRRIA 624
G + I D +S + VA D +PV + + P + ++K+ +P R+IA
Sbjct: 70 GTAICYIGDANESVQEEAGAPVAEDNMPQAVQPVKQENKPAASKKDRMKI--SPVARKIA 127
Query: 625 AQFKVDLSAVKATG 666
+ +DL +K TG
Sbjct: 128 EKAGLDLKQLKGTG 141
>UniRef50_Q7CNS6 Cluster: DIHYDROLIPOAMIDE ACETYLTRANSFERASE
COMPONENT OF ACETOIN CLEAVING SYSTEM; n=3; Brucella|Rep:
DIHYDROLIPOAMIDE ACETYLTRANSFERASE COMPONENT OF ACETOIN
CLEAVING SYSTEM - Brucella melitensis
Length = 428
Score = 45.6 bits (103), Expect = 0.001
Identities = 30/121 (24%), Positives = 48/121 (39%), Gaps = 3/121 (2%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I W V+ GD V+Q + E+ +DK V + + + G + L VGQ + +
Sbjct: 19 ISRWHVQDGDAVEQGQILFEIDNDKTVVEVDAPHAGTVKILKSSTTDEIEVGQSVASLFA 78
Query: 493 QDSENDGKPTDVAPDKPVAEIDA---PKTEQNQKIKVLTTPAVRRIAAQFKVDLSAVKAT 663
+ P A A A + Q + + TP RR+A +DL + T
Sbjct: 79 KGETITAPPAPAAAQNASAPKTADILAVVNKGQNGRAIATPLARRLANDAGIDLDRIGGT 138
Query: 664 G 666
G
Sbjct: 139 G 139
>UniRef50_Q3JBP0 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex dihydrolipoamide acyltransferase (E2) component
and related enzymes; n=1; Nitrosococcus oceani ATCC
19707|Rep: Pyruvate/2-oxoglutarate dehydrogenase complex
dihydrolipoamide acyltransferase (E2) component and
related enzymes - Nitrosococcus oceani (strain ATCC
19707 / NCIMB 11848)
Length = 447
Score = 45.2 bits (102), Expect = 0.001
Identities = 37/132 (28%), Positives = 59/132 (44%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL ++GE I + + V GD +++ + E+++DKA V I S G I L
Sbjct: 5 FKLPELGENIESGDVAKVLVSPGDTLEKDQPVLELETDKAVVEIPSTASGKIKELKVKAG 64
Query: 451 QTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQ 630
+GQ ++ + E G+ + D P A + PK EQ K + A Q
Sbjct: 65 DQVAIGQVILTL-----EEGGE--EAQEDVPAAR-EEPKPEQEHKPPEKSAAATGH--QQ 114
Query: 631 FKVDLSAVKATG 666
D+S ++A G
Sbjct: 115 PTTDVSPIEARG 126
>UniRef50_Q49111 Cluster: Dihydrolipoamide dehydrogenase; n=7;
root|Rep: Dihydrolipoamide dehydrogenase - Mycoplasma
capricolum
Length = 629
Score = 45.2 bits (102), Expect = 0.001
Identities = 31/95 (32%), Positives = 45/95 (47%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K +DIGEG+ E + E VKVGD V++ + V++DK I S G I + Q
Sbjct: 5 KFADIGEGLTEGTVAEVLVKVGDVVKEGQPLYFVETDKVNSEIPSPVAGKIAIINISTGQ 64
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEID 558
VG +++ID DG T A V ++
Sbjct: 65 EIKVGDVVIEID------DGSSTSTASTSKVEVVE 93
>UniRef50_A5V538 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Sphingomonas wittichii
RW1|Rep: Catalytic domain of components of various
dehydrogenase complexes - Sphingomonas wittichii RW1
Length = 396
Score = 45.2 bits (102), Expect = 0.001
Identities = 37/128 (28%), Positives = 56/128 (43%), Gaps = 1/128 (0%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+G + E +I EW V G+ V + V++DK + I + DG I L + T V
Sbjct: 18 LGLTMAEGLIAEWKVAPGEAVSAGQVLFVVETDKISNEIEAPADGTILSLLAEEGATVAV 77
Query: 466 GQPLVDIDVQDSENDGKPTDVAP-DKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQFKVD 642
G P+ G AP +PV P + + L+TP RR+A Q +D
Sbjct: 78 GAPVATWTGPGQGTGGTEQPPAPLSEPVGA--PPVAAPARGERRLSTPFARRLAQQAGID 135
Query: 643 LSAVKATG 666
L+ V +G
Sbjct: 136 LADVGGSG 143
>UniRef50_A0LP66 Cluster: 2-oxoglutarate dehydrogenase, E2 subunit,
dihydrolipoamide succinyltransferase; n=1;
Syntrophobacter fumaroxidans MPOB|Rep: 2-oxoglutarate
dehydrogenase, E2 subunit, dihydrolipoamide
succinyltransferase - Syntrophobacter fumaroxidans
(strain DSM 10017 / MPOB)
Length = 444
Score = 45.2 bits (102), Expect = 0.001
Identities = 33/132 (25%), Positives = 67/132 (50%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
+ K+ ++GE ++E ++ +W+ + GD V++ + + +++DK + +++ DG++ L +
Sbjct: 3 IEVKVPEVGESVQEALLVQWYRRDGDMVRKGEILFIIETDKVTLEVSADADGLLKILVPE 62
Query: 445 IDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIA 624
QT +G + ID + E KP P + +A KT + + A R A
Sbjct: 63 -GQTVRIGTVVATIDSEARE--AKPL------PARQPEAEKTGE------VVEKAAEREA 107
Query: 625 AQFKVDLSAVKA 660
A V +S V+A
Sbjct: 108 AAAPVPVSPVRA 119
>UniRef50_Q7RWS2 Cluster: Putative uncharacterized protein
NCU00050.1; n=2; Sordariomycetes|Rep: Putative
uncharacterized protein NCU00050.1 - Neurospora crassa
Length = 413
Score = 45.2 bits (102), Expect = 0.001
Identities = 41/153 (26%), Positives = 64/153 (41%), Gaps = 3/153 (1%)
Frame = +1
Query: 220 KELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVT 399
+ +R F TS A F + + + E I W VK GD D + E+++DKA +
Sbjct: 4 RSVRGFRTSAAALAAQNFTMPALSPTMTEGNIATWRVKEGDKFSAGDVLLEIETDKATMD 63
Query: 400 ITSRYDGIITRLY-HDIDQTALVGQPLVDI--DVQDSENDGKPTDVAPDKPVAEIDAPKT 570
+ ++ DG++ ++ +D + VG + I + D + P D AP AE AP
Sbjct: 64 VEAQDDGVMVKIMKNDGAKGVAVGARIAVIAEEGDDISSLEIPADAAPQSKPAE-SAPSA 122
Query: 571 EQNQKIKVLTTPAVRRIAAQFKVDLSAVKATGR 669
+ AV A Q SA K R
Sbjct: 123 PPPPTTADQSNVAVPESAPQNASSKSAPKPPKR 155
>UniRef50_Q830B2 Cluster: Acetyl-CoA carboxylase, biotin carboxyl
carrier protein; n=2; Enterococcus|Rep: Acetyl-CoA
carboxylase, biotin carboxyl carrier protein -
Enterococcus faecalis (Streptococcus faecalis)
Length = 162
Score = 44.8 bits (101), Expect = 0.002
Identities = 23/54 (42%), Positives = 32/54 (59%)
Frame = +1
Query: 316 KEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPL 477
KE FVKVGD V+ D +C V++ K IT+ DG+IT + + + GQPL
Sbjct: 102 KENFVKVGDTVKTGDVVCIVEAMKLMNEITATVDGVITEILVNNEDVVEFGQPL 155
>UniRef50_Q47KD8 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Thermobifida fusca YX|Rep: Pyruvate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase - Thermobifida fusca (strain YX)
Length = 431
Score = 44.8 bits (101), Expect = 0.002
Identities = 35/147 (23%), Positives = 67/147 (45%), Gaps = 20/147 (13%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+ + + E VI W +VGD V D + E+++DKA + + DG + + +T +
Sbjct: 9 LSDTMEEGVISSWVKQVGDKVSVGDVLVEIETDKAVMEYEAYEDGYLVQQTVREGETVPI 68
Query: 466 GQPL-VDIDVQDS------------ENDGKPTDVAP-------DKPVAEIDAPKTEQNQK 585
G + V D D+ + +P AP ++P A EQ K
Sbjct: 69 GAVIGVIADSPDAVPAAPEGGEGAEQKAEEPQQPAPAAQEAKEEQPTVPAPAAPAEQGGK 128
Query: 586 IKVLTTPAVRRIAAQFKVDLSAVKATG 666
+ L++P RR+A ++ +D++ ++ +G
Sbjct: 129 PRPLSSPLARRLAREYGLDITKIQGSG 155
>UniRef50_A5CVP1 Cluster: Pyruvate dehydrogenase complex E2
component; n=3; Bacteria|Rep: Pyruvate dehydrogenase
complex E2 component - Vesicomyosocius okutanii subsp.
Calyptogena okutanii (strain HA)
Length = 507
Score = 44.8 bits (101), Expect = 0.002
Identities = 27/76 (35%), Positives = 42/76 (55%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
L DIG+ EV I E V VGD + D+I ++ DK+++ I S Y GIIT++ +I
Sbjct: 9 LPDIGD-FYEVKIIEILVNVGDKINTNDSIVTLEKDKSSMKIPSPYTGIITKIEVNIGNK 67
Query: 457 ALVGQPLVDIDVQDSE 504
++ I+ + SE
Sbjct: 68 IKQNDIILSIESEYSE 83
Score = 38.3 bits (85), Expect = 0.17
Identities = 38/187 (20%), Positives = 84/187 (44%), Gaps = 11/187 (5%)
Frame = +1
Query: 142 KIKVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKE 321
++ + + +N LS ++ +E + ++ + +I+ + +IG+ E+ + E
Sbjct: 61 EVNIGNKIKQNDIILSIESEYSE-IQNTNKNIKNEYQKTEIIPVVVPNIGD-FDEIEVIE 118
Query: 322 WFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDI----D 489
V VGD + D+I ++SDKA++ I + G + + + +G +++I +
Sbjct: 119 ILVSVGDELSVEDSIITLESDKASMEIPTPVAGKVININVALGDKISLGTLILNIKSIAE 178
Query: 490 VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKI-------KVLTTPAVRRIAAQFKVDLS 648
+E + + P P P T +I +P++R++A + V+LS
Sbjct: 179 ETPTEIKIQSSTPIPIPPNPSTLTPITNNINQIVSEPIRGNSHASPSIRKLARELGVNLS 238
Query: 649 AVKATGR 669
+ TGR
Sbjct: 239 YITGTGR 245
>UniRef50_A3BC27 Cluster: Putative uncharacterized protein; n=2;
Oryza sativa|Rep: Putative uncharacterized protein -
Oryza sativa subsp. japonica (Rice)
Length = 549
Score = 44.8 bits (101), Expect = 0.002
Identities = 32/128 (25%), Positives = 68/128 (53%), Gaps = 10/128 (7%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDID 489
I +W + G+ ++ D ICE+++DKA + S +G + + L + + VGQP+ +
Sbjct: 168 IAKWRKQEGEKIEVGDVICEIETDKATLEFESLEEGYLAKILAPEGSKDVQVGQPIA-VT 226
Query: 490 VQDSEN-DGKPTDVA-----PDKPVA-EIDAPKTEQNQKIKVLT--TPAVRRIAAQFKVD 642
V+D E+ P D + ++ +A E +T+ ++ ++T +PA + + + ++D
Sbjct: 227 VEDLEDIKNIPADASFGGEQKEQSIASEAQKVETDAAKESSIITRISPAAKLLIKEHRLD 286
Query: 643 LSAVKATG 666
S + A+G
Sbjct: 287 QSVLNASG 294
>UniRef50_Q8RWN9 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 2 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=14; cellular
organisms|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 2 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 539
Score = 44.8 bits (101), Expect = 0.002
Identities = 44/201 (21%), Positives = 85/201 (42%), Gaps = 29/201 (14%)
Frame = +1
Query: 151 VTTQSARNGSQLSYKTPLNESLSKELRH---FHTSHAVNKIVAFKLSDIGEGIREVVIKE 321
++T S + S ++ E +S ++R F +S + + + + E I
Sbjct: 71 ISTTSTKLSSPMAGPKLFKEFISSQMRSVRGFSSSSDLPPHQEIGMPSLSPTMTEGNIAR 130
Query: 322 WFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDS 501
W K GD V + +CEV++DKA V + +G + ++ + + ++ I V+D
Sbjct: 131 WLKKEGDKVAPGEVLCEVETDKATVEMECMEEGFLAKIVKEEGAKEIQVGEVIAITVEDE 190
Query: 502 EN-----DGKP-TDVAPDKPVA----------EIDAPKTEQNQKI----------KVLTT 603
++ D P +D P P A +++ P + KI ++ +
Sbjct: 191 DDIQKFKDYTPSSDTGPAAPEAKPAPSLPKEEKVEKPASAPEAKISKPSSAPSEDRIFAS 250
Query: 604 PAVRRIAAQFKVDLSAVKATG 666
P R++A V LS++K TG
Sbjct: 251 PLARKLAEDNNVPLSSIKGTG 271
>UniRef50_Q4FS31 Cluster: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex; n=2;
Psychrobacter|Rep: Dihydrolipoyllysine acetyltransferase
component of pyruvate dehydrogenase complex -
Psychrobacter arcticum
Length = 578
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/98 (25%), Positives = 51/98 (52%), Gaps = 1/98 (1%)
Frame = +1
Query: 295 GIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP 474
G+ + E V VGD + + DNI ++SDKA+V + S G +T++ + G
Sbjct: 9 GVDSAEVSEIMVAVGDVIAKDDNIILLESDKASVEVPSSAAGKVTKISVAVGDQVSEGMV 68
Query: 475 LVDIDVQ-DSENDGKPTDVAPDKPVAEIDAPKTEQNQK 585
L++++ + ++++D + T+ A + + E+ QK
Sbjct: 69 LIELESETENQDDSQSTEAAVADTQDKSRDTEQEETQK 106
Score = 41.1 bits (92), Expect = 0.024
Identities = 30/115 (26%), Positives = 48/115 (41%), Gaps = 5/115 (4%)
Frame = +1
Query: 295 GIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP 474
G+ E + E V VGD V +I ++SDKA+V + + G + ++ GQ
Sbjct: 138 GVDEAQVSEIMVSVGDMVTADQSILLIESDKASVEVPAPQAGKVEKILVQTGDMVANGQD 197
Query: 475 LVDIDVQDSEN-----DGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIA 624
+ I Q S+N + K D P K + +QK T A ++ A
Sbjct: 198 FIVIIGQSSDNTNITSEAKAEDAQSQDPKPAATDEKADASQKADKQVTTAPKQAA 252
>UniRef50_Q48TW1 Cluster: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex; n=41;
Streptococcus|Rep: Dihydrolipoamide acetyltransferase
component of pyruvate dehydrogenase complex -
Streptococcus pyogenes serotype M28
Length = 469
Score = 44.4 bits (100), Expect = 0.003
Identities = 39/148 (26%), Positives = 63/148 (42%), Gaps = 21/148 (14%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+G ++E I EW + GD V + D + E+ SDK + + + G++ ++ T V
Sbjct: 10 LGVDMQEGEIIEWKKQEGDTVNEGDILLEIMSDKTNMELEAEDSGVLLKIVRPAGDTVPV 69
Query: 466 GQPLVDIDVQDSEND-----GKPTD------------VAPDK----PVAEIDAPKTEQNQ 582
+ + I + D K T+ VAP + P ++ A Q
Sbjct: 70 TEVIGYIGAEGESVDTIASSEKTTEIPVPASADAGPAVAPKENVASPAPQVAATAIPQGN 129
Query: 583 KIKVLTTPAVRRIAAQFKVDLSAVKATG 666
KV TPA R+ AA+ +DL V TG
Sbjct: 130 GGKVRATPAARKAAAEMGIDLGQVPGTG 157
>UniRef50_Q4AFC2 Cluster: Biotin/lipoyl attachment; n=1; Chlorobium
phaeobacteroides BS1|Rep: Biotin/lipoyl attachment -
Chlorobium phaeobacteroides BS1
Length = 119
Score = 44.4 bits (100), Expect = 0.003
Identities = 25/90 (27%), Positives = 44/90 (48%), Gaps = 1/90 (1%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+GE I E I W VG+ V++ D++ E+ +DK I S +G++++L V
Sbjct: 11 LGESIIEATITRWVKNVGEAVEEDDSLVEIATDKVDSEIPSPVEGVLSKLLFKEGDVVPV 70
Query: 466 GQPLVDIDVQDSENDGKPTDV-APDKPVAE 552
G + I+++ ++ D A K V E
Sbjct: 71 GTVIALIEMEGEGSEETTVDTPAAXKTVIE 100
>UniRef50_Q0LRZ3 Cluster: Dihydrolipoamide acetyltransferase, long
form; n=1; Caulobacter sp. K31|Rep: Dihydrolipoamide
acetyltransferase, long form - Caulobacter sp. K31
Length = 415
Score = 44.4 bits (100), Expect = 0.003
Identities = 34/136 (25%), Positives = 56/136 (41%), Gaps = 9/136 (6%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+ G+ E I W VGD + D I E+++DKA + + + G I R+ T V
Sbjct: 10 LSAGMEEATIVRWLKTVGDVIAPGDLIAEIETDKATIELEAEQTGKIGRILAAEGATVAV 69
Query: 466 GQPLVDI--------DVQDSENDGKPT-DVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRR 618
+ + D+ ++E T VA A A + Q ++ +P RR
Sbjct: 70 NAEIALLLAEGEHVDDLSEAEKAAPETASVAVTSRDAAAAAGSMDSTQHRRIAASPLARR 129
Query: 619 IAAQFKVDLSAVKATG 666
IA V L ++ +G
Sbjct: 130 IAQAKGVGLDTLRGSG 145
>UniRef50_Q5KIM3 Cluster: Dihydrolipoyllysine-residue
acetyltransferase, putative; n=2; Basidiomycota|Rep:
Dihydrolipoyllysine-residue acetyltransferase, putative
- Cryptococcus neoformans (Filobasidiella neoformans)
Length = 479
Score = 44.4 bits (100), Expect = 0.003
Identities = 34/137 (24%), Positives = 63/137 (45%), Gaps = 9/137 (6%)
Frame = +1
Query: 229 RHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
R TS N + F + + + E + +W K G++ D + E+++DKA + + +
Sbjct: 24 RTLRTSAPSNVLSKFAMPAMSPTMTEGGVAQWKKKEGESFSAGDVLIEIETDKATIDVEA 83
Query: 409 RYDGIITRLY-HDIDQTALVGQPLV-------DIDVQDSENDGKPTDVAPDKPVAEIDAP 564
+ DGI+ ++ D + VG P+ D+ D+ ++ AP + A
Sbjct: 84 QDDGIMAKIIAQDGTKNIAVGTPIAIIGEEGDDLSQADALAAESQSESAPSQKEAAPKEE 143
Query: 565 KT-EQNQKIKVLTTPAV 612
KT + +K + TTPAV
Sbjct: 144 KTAPKEEKSESSTTPAV 160
>UniRef50_Q98FT5 Cluster: Dihydrolipoamide acetyltransferase
homoserine dehydrogenase; n=23; Alphaproteobacteria|Rep:
Dihydrolipoamide acetyltransferase homoserine
dehydrogenase - Rhizobium loti (Mesorhizobium loti)
Length = 454
Score = 44.0 bits (99), Expect = 0.003
Identities = 29/88 (32%), Positives = 43/88 (48%), Gaps = 1/88 (1%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I WF + G V++ D + E+++DKAA+ I + G++ + VG P+ I
Sbjct: 19 ISRWFAEEGARVKKGDVLFEIETDKAAMEIDAPASGVLRDVSGKEGVDIPVGAPVAWI-Y 77
Query: 493 QDSENDGKPTDVAPDKP-VAEIDAPKTE 573
D E G D AP P V E+ A TE
Sbjct: 78 ADDEAYGAKQDAAPISPLVGEMSAKSTE 105
>UniRef50_Q3A0D1 Cluster: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase; n=2;
Desulfuromonadales|Rep: 2-oxoglutarate dehydrogenase, E2
component/dihydrolipoamide succinyltransferase -
Pelobacter carbinolicus (strain DSM 2380 / Gra Bd 1)
Length = 396
Score = 44.0 bits (99), Expect = 0.003
Identities = 17/52 (32%), Positives = 33/52 (63%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIIT 429
++ +IGE I E + +W + G VQ+ D +CE+++DK + + + DG++T
Sbjct: 4 RIPEIGESIIEAKLAKWHCQDGAQVQKDDLLCELETDKITLELFAETDGVVT 55
>UniRef50_Q0VRX7 Cluster: Pyruvate dehydrogenase, E2 component; n=4;
Proteobacteria|Rep: Pyruvate dehydrogenase, E2 component
- Alcanivorax borkumensis (strain SK2 / ATCC 700651 /
DSM 11573)
Length = 564
Score = 44.0 bits (99), Expect = 0.003
Identities = 44/156 (28%), Positives = 67/156 (42%), Gaps = 17/156 (10%)
Frame = +1
Query: 250 AVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIIT 429
A ++ K+ D+G+ I I E V VGD + + I V+SDKA++ I S G +
Sbjct: 137 AASRSETVKVPDLGD-IDAAEIIEVNVAVGDELDEEQIIVVVESDKASLEIPSPKAGKVE 195
Query: 430 RLYHDIDQT----------ALVGQPLVDIDVQ-DSENDGKPTDVAPDKPVAEIDAPKTEQ 576
+ + A+ G P + Q + E DG D +P+ + P Q
Sbjct: 196 SVNVSVGDKVGSGDALITLAVTGTPAAEESAQPEREQDGAEQDSSPETASSSGSTPSRAQ 255
Query: 577 ------NQKIKVLTTPAVRRIAAQFKVDLSAVKATG 666
+ V PAVR++A + VDLS V TG
Sbjct: 256 PSDAGGSPSRPVHAGPAVRKLARETGVDLSQVSGTG 291
Score = 35.9 bits (79), Expect = 0.89
Identities = 22/83 (26%), Positives = 38/83 (45%)
Frame = +1
Query: 283 DIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTAL 462
D+G V I E V VGD + D I ++SDKA V + + G + + +
Sbjct: 10 DVGSS-DPVDIIEIRVNVGDTISAEDTIIVLESDKATVEVPAPQGGKVASISVKVGDRVK 68
Query: 463 VGQPLVDIDVQDSENDGKPTDVA 531
G +++++V D + DV+
Sbjct: 69 EGDAVMELEVADGDATDSAEDVS 91
>UniRef50_A3HTS0 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=2; Bacteroidetes|Rep:
2-oxo acid dehydrogenases acyltransferase (Catalytic
domain) protein - Algoriphagus sp. PR1
Length = 432
Score = 44.0 bits (99), Expect = 0.003
Identities = 26/104 (25%), Positives = 50/104 (48%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHD 444
V + +GE I E I W K G+ ++Q +++ EV +DK + + + G++ ++
Sbjct: 4 VEMLMPKMGESIIEGTILGWLKKEGETIEQDESVLEVATDKVDTEVPATHPGVLKKILAK 63
Query: 445 IDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQ 576
VG P+ I ++EN+ + P+ PVA + E+
Sbjct: 64 EGDVVAVGAPIAII---ETENEVE----TPNSPVASESKEEKEE 100
>UniRef50_A1ZE93 Cluster: Pyruvate dehydrogenase complex
dihydrolipoamide acetyltransferase; n=7; Bacteria|Rep:
Pyruvate dehydrogenase complex dihydrolipoamide
acetyltransferase - Microscilla marina ATCC 23134
Length = 547
Score = 44.0 bits (99), Expect = 0.003
Identities = 23/71 (32%), Positives = 39/71 (54%)
Frame = +1
Query: 241 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 420
T V+ + + + + E VI W KVGDN+Q+ D I EV++DKA + + + +G
Sbjct: 115 TEVTVDNATVVTMPKMSDTMEEGVIVSWLKKVGDNIQEGDIIAEVETDKATMELEAYDEG 174
Query: 421 IITRLYHDIDQ 453
T LY +++
Sbjct: 175 --TLLYVAVEE 183
Score = 42.7 bits (96), Expect = 0.008
Identities = 26/64 (40%), Positives = 38/64 (59%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+SD E E VI +W KVGD +Q+ D I EV++DKA + + S +G T LY ++
Sbjct: 9 KMSDTME---EGVIAKWLKKVGDTIQEGDIIAEVETDKATMELESYDEG--TLLYVAVED 63
Query: 454 TALV 465
+V
Sbjct: 64 GGVV 67
>UniRef50_Q9SXV7 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Lithospermum erythrorhizon|Rep: Dihydrolipoamide
acetyltransferase - Lithospermum erythrorhizon
Length = 189
Score = 44.0 bits (99), Expect = 0.003
Identities = 27/103 (26%), Positives = 53/103 (51%), Gaps = 3/103 (2%)
Frame = +1
Query: 226 LRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 405
+RHF ++ +++ + + + + I +W K GD + D +CE+++DKA +
Sbjct: 63 VRHFSSADPPQTVLS--MPALSPTMSQGNIAKWLKKEGDKIAAGDVLCEIETDKATLEYE 120
Query: 406 SRYDGIITR-LYHDIDQTALVGQPL-VDIDVQDS-ENDGKPTD 525
S DG + + L D + VG+P+ + ++ QD +N P D
Sbjct: 121 SVEDGFLAKILVPDGSKDVPVGKPIAITVEEQDDLKNVSVPVD 163
>UniRef50_Q1E5N3 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial; n=8; Dikarya|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex,
mitochondrial - Coccidioides immitis
Length = 484
Score = 44.0 bits (99), Expect = 0.003
Identities = 23/84 (27%), Positives = 43/84 (51%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
K+ + E I + +K++ ++GD V++ + + +++DK VT+ + GII +
Sbjct: 97 KVPQMAESISDGTLKQFSKQIGDFVERDEELATIETDKIDVTVNAPESGIIKEFLAKEED 156
Query: 454 TALVGQPLVDIDVQDSENDGKPTD 525
T VGQ LV + +EN D
Sbjct: 157 TVTVGQDLVKLQ-PSTENPSSGKD 179
>UniRef50_P19262 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor; n=21;
Ascomycota|Rep: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex, mitochondrial precursor -
Saccharomyces cerevisiae (Baker's yeast)
Length = 463
Score = 44.0 bits (99), Expect = 0.003
Identities = 19/85 (22%), Positives = 45/85 (52%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
K + ++ + E + E +KE+ VGD +++ + + +++DK + + S G +T+L
Sbjct: 72 KSTSIEVPPMAESLTEGSLKEYTKNVGDFIKEDELLATIETDKIDIEVNSPVSGTVTKLN 131
Query: 439 HDIDQTALVGQPLVDIDVQDSENDG 513
+ T VG+ L ++ ++ +G
Sbjct: 132 FKPEDTVTVGEELAQVEPGEAPAEG 156
>UniRef50_Q98ED1 Cluster: Dihydrolipoamide succinyl transferase;
n=8; Bacteria|Rep: Dihydrolipoamide succinyl transferase
- Rhizobium loti (Mesorhizobium loti)
Length = 424
Score = 43.6 bits (98), Expect = 0.004
Identities = 24/86 (27%), Positives = 41/86 (47%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
++ +GE + E I +WF KVGD + + + E+++DK V + + G + + +
Sbjct: 6 RVPTLGESVTEATIGKWFKKVGDAIAVDEPLVELETDKVTVEVPAAAAGTLGEIVAKEGE 65
Query: 454 TALVGQPLVDIDVQDSENDGKPTDVA 531
T VG L I S KP V+
Sbjct: 66 TVGVGALLGSISAGGSAPATKPQAVS 91
>UniRef50_Q82SG4 Cluster: SucB; dihydrolipoamide succinyltransferase
(Component of 2- oxoglutarate dehydrogenase complex)
protein; n=4; Bacteria|Rep: SucB; dihydrolipoamide
succinyltransferase (Component of 2- oxoglutarate
dehydrogenase complex) protein - Nitrosomonas europaea
Length = 425
Score = 43.6 bits (98), Expect = 0.004
Identities = 28/140 (20%), Positives = 62/140 (44%), Gaps = 4/140 (2%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
++ K+ + E + E + W + G+ V++ +N+ ++++DK + + + GI+ +
Sbjct: 2 LIEVKVPALSESVAEATLINWHKQPGEYVERGENLIDIETDKVVLELPAPQSGILAEIIR 61
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAP-DKPVAEIDAPKTEQNQKIKVLTTPAVRR 618
+ T G+ + ID E AP D EI + L P+ ++
Sbjct: 62 NDGATVTSGEIIARIDTAAKETKTAAQQPAPIDSGHLEITESTVASMHPAQPL-MPSAKK 120
Query: 619 IAAQFKV---DLSAVKATGR 669
A + + +++A+ TGR
Sbjct: 121 AAEENGLTMEEIAAIHGTGR 140
>UniRef50_Q2S4D4 Cluster: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein; n=1; Salinibacter ruber DSM
13855|Rep: 2-oxo acid dehydrogenases acyltransferase
(Catalytic domain) protein - Salinibacter ruber (strain
DSM 13855)
Length = 639
Score = 43.6 bits (98), Expect = 0.004
Identities = 29/114 (25%), Positives = 51/114 (44%), Gaps = 4/114 (3%)
Frame = +1
Query: 238 HTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD 417
HT+ + + V ++ +GE I E + W + GD V+Q + + E+ +DK + S
Sbjct: 27 HTTEIMAQ-VDVEMPKMGESITEGTVIAWHKQPGDEVEQDEILLEIGTDKVDTEVPSPKG 85
Query: 418 GIITRLYHDIDQTALVGQPLVDIDVQ----DSENDGKPTDVAPDKPVAEIDAPK 567
G++T + T VG + +D + + D +P AP A D K
Sbjct: 86 GVLTETLVEEGDTVEVGTIIATLDTDTAAAEVDADDEPPAEAPSDDEAAADEAK 139
Score = 37.9 bits (84), Expect = 0.22
Identities = 25/98 (25%), Positives = 48/98 (48%), Gaps = 1/98 (1%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+GE I E + W+ +G+ V + I E+ +DK + S +G++T + +T V
Sbjct: 180 MGESITEGTVVAWYKDIGEAVAIDETILEIGTDKVDTEVPSPAEGVLTEKLVEEGETVEV 239
Query: 466 GQPLVDIDVQDSENDGKPTDVAPDKP-VAEIDAPKTEQ 576
G +V + ++E G A D+P + AP+ ++
Sbjct: 240 G-TVVALLASEAE-AGSVEPPASDEPDTTQETAPEADE 275
>UniRef50_A1ZHD0 Cluster: Dihydrolipoyllysine-residue
succinyltransferase component of 2- oxoglutarate
dehydrogenase complex; n=2; Bacteroidetes|Rep:
Dihydrolipoyllysine-residue succinyltransferase
component of 2- oxoglutarate dehydrogenase complex -
Microscilla marina ATCC 23134
Length = 454
Score = 43.6 bits (98), Expect = 0.004
Identities = 30/138 (21%), Positives = 60/138 (43%), Gaps = 9/138 (6%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
+V + +GE + E I +W VGD +++ + + EV +DK + + + G++ +
Sbjct: 3 LVEMVMPKMGESVMEGTILQWLKAVGDEIEEDEPVLEVATDKVDTEVPATHAGVLKEVLA 62
Query: 442 DIDQTALVGQPLVDI--------DVQDSENDGKPTDVAP-DKPVAEIDAPKTEQNQKIKV 594
VGQ + I D S+ + P VA ++ +A+ T N +
Sbjct: 63 QEGDVVQVGQTIAIISTDGDAPADAPASQPEAAPATVAAVEQTIAQAQV-ATANNNGTER 121
Query: 595 LTTPAVRRIAAQFKVDLS 648
L PA R + ++++
Sbjct: 122 LNAPATGRFYSPLVLNIA 139
>UniRef50_A0LSF1 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=1; Acidothermus
cellulolyticus 11B|Rep: Catalytic domain of components
of various dehydrogenase complexes - Acidothermus
cellulolyticus (strain ATCC 43068 / 11B)
Length = 449
Score = 43.6 bits (98), Expect = 0.004
Identities = 24/92 (26%), Positives = 49/92 (53%), Gaps = 3/92 (3%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+ + ++E I +W KVGD V++ D + E+++DKA + + + G++ ++ + + +
Sbjct: 9 LSDTMQEGTITQWTKKVGDQVEKGDVLAEIETDKAVMELEAYDSGVLEKILVEPGKPVPI 68
Query: 466 GQPLVDIDVQD--SENDGKPT-DVAPDKPVAE 552
G P+ I + E G T AP +P A+
Sbjct: 69 GTPIAIIGSGEGLQEPTGDSTAHAAPAEPKAD 100
>UniRef50_Q9SQI8 Cluster: Dihydrolipoamide S-acetyltransferase;
n=32; cellular organisms|Rep: Dihydrolipoamide
S-acetyltransferase - Arabidopsis thaliana (Mouse-ear
cress)
Length = 480
Score = 43.6 bits (98), Expect = 0.004
Identities = 50/196 (25%), Positives = 79/196 (40%), Gaps = 26/196 (13%)
Frame = +1
Query: 157 TQSARNGSQLSYKTPLNESLSKELRHFHTSHAVNKIVAFKLSDI-----GEGIREVVIKE 321
T S N S S +P S+ TSH + V K+ +I + E I
Sbjct: 15 TNSKSNISFASSVSPSLRSVVFRSTTPATSHRRSMTVRSKIREIFMPALSSTMTEGKIVS 74
Query: 322 WFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQP---LVDIDV 492
W G+ + + +++ V+SDKA + + + YDG + + +TA VG L + +
Sbjct: 75 WIKTEGEKLAKGESVVVVESDKADMDVETFYDGYLAAIVVGEGETAPVGAAIGLLAETEA 134
Query: 493 QDSENDGKPTD---------VAPD-KPVAEIDAPKTEQNQKI--------KVLTTPAVRR 618
+ E K V P PV AP Q + K + TP ++
Sbjct: 135 EIEEAKSKAASKSSSSVAEAVVPSPPPVTSSPAPAIAQPAPVTAVSDGPRKTVATPYAKK 194
Query: 619 IAAQFKVDLSAVKATG 666
+A Q KVD+ +V TG
Sbjct: 195 LAKQHKVDIESVAGTG 210
>UniRef50_Q9FLQ4 Cluster: 2-oxoglutarate dehydrogenase E2 subunit;
n=15; Magnoliophyta|Rep: 2-oxoglutarate dehydrogenase E2
subunit - Arabidopsis thaliana (Mouse-ear cress)
Length = 464
Score = 43.6 bits (98), Expect = 0.004
Identities = 28/117 (23%), Positives = 51/117 (43%), Gaps = 2/117 (1%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
+V + +GE I + + + K GD V+ + I ++++DK + I S G+I
Sbjct: 93 VVEAVVPHMGESITDGTLAAFLKKPGDRVEADEAIAQIETDKVTIDIASPASGVIQEFLV 152
Query: 442 DIDQTALVGQPLVDIDVQ-DSENDGKPTDVAPDKPVAEIDAPKTEQN-QKIKVLTTP 606
T G + I D+ + P++ AP+KP + P + + KV P
Sbjct: 153 KEGDTVEPGNKVARISTSADAVSHVAPSEKAPEKPAPKPSPPAEKPKVESTKVAEKP 209
>UniRef50_O66113 Cluster: Pyruvate dehydrogenase E1 component
subunit beta; n=99; Bacteria|Rep: Pyruvate dehydrogenase
E1 component subunit beta - Zymomonas mobilis
Length = 462
Score = 43.6 bits (98), Expect = 0.004
Identities = 25/122 (20%), Positives = 59/122 (48%), Gaps = 3/122 (2%)
Frame = +1
Query: 265 VAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYH 441
+ K+ + + E + W VK GD+++ + + E+++DKA + + +G+IT+ L
Sbjct: 3 IELKMPALSPTMEEGTLTRWLVKEGDSIKAGEILAEIETDKAIMEFEAVDEGVITKILIP 62
Query: 442 DIDQTALVGQPL--VDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVR 615
+ + VG + + D D DG + ++ A + +P + ++ TP++
Sbjct: 63 EGSENVKVGTAIAYLGTDANDVTLDGASAETKAEES-APVASPAKTEAAAVEEAATPSLG 121
Query: 616 RI 621
++
Sbjct: 122 KV 123
>UniRef50_UPI0000E4A22B Cluster: PREDICTED: similar to pyruvate
dehydrogenase complex, component X; n=4;
Strongylocentrotus purpuratus|Rep: PREDICTED: similar to
pyruvate dehydrogenase complex, component X -
Strongylocentrotus purpuratus
Length = 482
Score = 43.2 bits (97), Expect = 0.006
Identities = 30/96 (31%), Positives = 49/96 (51%), Gaps = 5/96 (5%)
Frame = +1
Query: 304 EVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY-----HDIDQTALVG 468
E I W GD + D ICE+++DKA V + + DGI+ ++ +I TAL+G
Sbjct: 68 EGTIVSWLKAEGDPIAAGDGICEIETDKATVIMDADDDGIMAKILVPEGSKNIPITALIG 127
Query: 469 QPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQ 576
L+ + +D ++ PT A P + D+PK +
Sbjct: 128 --LMVPEGEDYKDVDMPTQAA---PTSTGDSPKQSE 158
>UniRef50_Q9PJZ6 Cluster: 2-oxo acid dehydrogenase, E2 component,
lipoamide acyltransferase; n=9; Chlamydiaceae|Rep: 2-oxo
acid dehydrogenase, E2 component, lipoamide
acyltransferase - Chlamydia muridarum
Length = 410
Score = 43.2 bits (97), Expect = 0.006
Identities = 32/149 (21%), Positives = 62/149 (41%)
Frame = +1
Query: 220 KELRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVT 399
K + F +S + F+ IGE ++ W +VGD++Q+ + + EV +DK A
Sbjct: 9 KNTKTFTSSEIRGFMFEFRFPKIGETASGGIVVRWLKQVGDSIQKDEPLIEVSTDKIATE 68
Query: 400 ITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQN 579
++ G++ + G L + + PT V + P+ E ++ +N
Sbjct: 69 LSPSQAGVLEECLVQEGEEVSPGDVLARLREISPVDTSVPTSV-EESPIKE-ESLVNREN 126
Query: 580 QKIKVLTTPAVRRIAAQFKVDLSAVKATG 666
Q + V+R + +L + TG
Sbjct: 127 QWLSPAVLGIVQREGLDLQ-ELQKISGTG 154
>UniRef50_Q3CI28 Cluster: Biotin/lipoyl attachment:Catalytic domain
of components of various dehydrogenase complexes:E3
binding; n=2; Thermoanaerobacter ethanolicus|Rep:
Biotin/lipoyl attachment:Catalytic domain of components
of various dehydrogenase complexes:E3 binding -
Thermoanaerobacter ethanolicus ATCC 33223
Length = 382
Score = 43.2 bits (97), Expect = 0.006
Identities = 30/127 (23%), Positives = 59/127 (46%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+G ++E + W KVGD V++ + I EV +DK + S DGI+ ++ + + V
Sbjct: 10 LGLTMKEGRVDRWLKKVGDIVKKGEEIVEVSTDKITNVVESPADGILAKILVNEGEIVPV 69
Query: 466 GQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQFKVDL 645
P+ I + + + + E++++ + TP +R+A + +DL
Sbjct: 70 ATPIGIITAEGEKLE------------------EVEKSEEKFIKATPVAKRLAKENNIDL 111
Query: 646 SAVKATG 666
S + TG
Sbjct: 112 SLITGTG 118
>UniRef50_A6Q3I4 Cluster: Pyruvate/2-oxoglutarate dehydrogenase
complex, E2 component, dihydrolipoamide
acetyltransferase; n=1; Nitratiruptor sp. SB155-2|Rep:
Pyruvate/2-oxoglutarate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase -
Nitratiruptor sp. (strain SB155-2)
Length = 408
Score = 43.2 bits (97), Expect = 0.006
Identities = 35/117 (29%), Positives = 57/117 (48%), Gaps = 5/117 (4%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
KIV LSD + + +IK W VK GD V + D I EV+SDKA + + + DG++ +L
Sbjct: 4 KIVMPVLSDTMD--KGKLIK-WHVKEGDVVHKGDVIAEVESDKAIMEVQTFKDGVVKKLL 60
Query: 439 HDIDQTALVGQPLVDIDVQDSE-----NDGKPTDVAPDKPVAEIDAPKTEQNQKIKV 594
V +P+ +D + E + + +K V + + K + QK +V
Sbjct: 61 VKEGDEVPVKEPIAILDTEVKEPVTKTQASEQKEQPKEKTVVQKEESKPQTPQKSEV 117
>UniRef50_A5ZAG1 Cluster: Putative uncharacterized protein; n=1;
Eubacterium ventriosum ATCC 27560|Rep: Putative
uncharacterized protein - Eubacterium ventriosum ATCC
27560
Length = 148
Score = 43.2 bits (97), Expect = 0.006
Identities = 19/55 (34%), Positives = 35/55 (63%)
Frame = +1
Query: 325 FVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDID 489
FV+VGD V++ + V++ K I S +DG++T++ + +QT GQPL +++
Sbjct: 94 FVQVGDTVKKGQVVAIVEAMKLMNEIESEFDGVVTKVLVENEQTVEYGQPLFEVE 148
>UniRef50_A5MZI5 Cluster: PdhC; n=6; Clostridium|Rep: PdhC -
Clostridium kluyveri DSM 555
Length = 444
Score = 43.2 bits (97), Expect = 0.006
Identities = 33/135 (24%), Positives = 65/135 (48%), Gaps = 8/135 (5%)
Frame = +1
Query: 286 IGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALV 465
+G + E I+ W GD V++ + + +V +DK + ++ GI+ ++ +TA
Sbjct: 10 LGLTMTEGEIETWHKSEGDEVKKGEVLFDVTTDKLTNEVEAKESGILRKILVKEGETAKC 69
Query: 466 GQPL-----VDIDVQD--SENDGKPTDVAP-DKPVAEIDAPKTEQNQKIKVLTTPAVRRI 621
+P+ D D+ E+ GK +V P ++P D P E+ +I++ +P + +
Sbjct: 70 LEPVAIIAGADEDISSLLKESVGKEVEVVPVEEPSIREDIP-VEREGRIRI--SPLAKNL 126
Query: 622 AAQFKVDLSAVKATG 666
A + VD + TG
Sbjct: 127 AKKSGVDYEVITGTG 141
>UniRef50_Q4DYI5 Cluster: Dihydrolipoamide acetyltransferase,
putative; n=2; Trypanosomatidae|Rep: Dihydrolipoamide
acetyltransferase, putative - Trypanosoma cruzi
Length = 269
Score = 43.2 bits (97), Expect = 0.006
Identities = 31/100 (31%), Positives = 48/100 (48%), Gaps = 1/100 (1%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYD-GIITRLYHDIDQTALVGQPLVDID 489
I EW KVGD V + + C VQ+DKA V T+ +D G + ++ +T V + + +
Sbjct: 28 IVEWKKKVGDLVNENEVFCTVQTDKAVVDYTNTFDAGYLAKILCHSGETVPVAKTIA-VM 86
Query: 490 VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
V+D + K D P E +AP E + +PA
Sbjct: 87 VEDEADIPKIADYRP-----EGEAPGEEVKSDAPAVPSPA 121
>UniRef50_Q0WQF7 Cluster: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor; n=4;
Magnoliophyta|Rep: Dihydrolipoyllysine-residue
acetyltransferase component 1 of pyruvate dehydrogenase
complex, mitochondrial precursor - Arabidopsis thaliana
(Mouse-ear cress)
Length = 637
Score = 43.2 bits (97), Expect = 0.006
Identities = 31/128 (24%), Positives = 64/128 (50%), Gaps = 10/128 (7%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDID 489
I +W+ K GD ++ D I E+++DKA + S +G + + L + + VG+P+ I
Sbjct: 229 IAKWWKKEGDKIEVGDVIGEIETDKATLEFESLEEGYLAKILIPEGSKDVAVGKPIALI- 287
Query: 490 VQDSEN---------DGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQFKVD 642
V+D+E+ D + P + +D P + K+ +PA + + + ++
Sbjct: 288 VEDAESIEAIKSSSAGSSEVDTVKEVPDSVVDKPTERKAGFTKI--SPAAKLLILEHGLE 345
Query: 643 LSAVKATG 666
S+++A+G
Sbjct: 346 ASSIEASG 353
Score = 38.7 bits (86), Expect = 0.13
Identities = 14/41 (34%), Positives = 26/41 (63%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
+ +W K GD V+ D +CE+++DKA V S+ +G + ++
Sbjct: 102 VVKWMKKEGDKVEVGDVLCEIETDKATVEFESQEEGFLAKI 142
>UniRef50_Q4RLV1 Cluster: Chromosome 10 SCAF15019, whole genome
shotgun sequence; n=5; Bilateria|Rep: Chromosome 10
SCAF15019, whole genome shotgun sequence - Tetraodon
nigroviridis (Green puffer)
Length = 461
Score = 42.7 bits (96), Expect = 0.008
Identities = 31/115 (26%), Positives = 58/115 (50%), Gaps = 4/115 (3%)
Frame = +1
Query: 103 RSVFQLRTVNRC---RKIKVTTQSARNGSQLSYKTPLNESLSKELRHFHTSHAV-NKIVA 270
RS+ LR N+ R + T + + K+ L ++ + +++F TS A +++V
Sbjct: 14 RSLSALRQGNQALARRSLSALTINTSISVNNNVKSNLRTNVFR-IQYFRTSVAYRDEVVT 72
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
K E + E ++ W VGD V + + +CE+++DK +V + S G+I L
Sbjct: 73 VKTPAFAESVTEGDVR-WEKAVGDTVTEDEVVCEIETDKTSVQVPSPAAGVIEEL 126
>UniRef50_Q5L233 Cluster: Pyruvate dehydrogenase E2; n=2;
Geobacillus|Rep: Pyruvate dehydrogenase E2 - Geobacillus
kaustophilus
Length = 436
Score = 42.7 bits (96), Expect = 0.008
Identities = 40/135 (29%), Positives = 59/135 (43%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
+V L + + E I W V GD V++ + EVQ++KA I + G + +
Sbjct: 2 VVEVTLPKLSDSHDESFITFWHVSEGDAVEKGATLVEVQTEKAVSEIHAPESGTVKEIKK 61
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRI 621
TA VG+ L I V+ DG P+TE IK+ TP V+++
Sbjct: 62 KRGDTAKVGEVLAVIAVETFAPDG--------------GDPQTE----IKI--TPRVKKL 101
Query: 622 AAQFKVDLSAVKATG 666
A + VD S V TG
Sbjct: 102 AKELGVDWSTVTPTG 116
>UniRef50_Q59658 Cluster: Dihydrolipoamide acetyltransferase; n=3;
Pelobacter|Rep: Dihydrolipoamide acetyltransferase -
Pelobacter carbinolicus
Length = 450
Score = 42.7 bits (96), Expect = 0.008
Identities = 27/89 (30%), Positives = 44/89 (49%), Gaps = 4/89 (4%)
Frame = +1
Query: 256 NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRL 435
N+I+A + G + E I W + GD ++ I EV++DK A + S +GI+ R
Sbjct: 4 NRIIALTMPKWGLTMEEGTISSWLMDEGDTIEVGSEILEVETDKIAQPVESAVEGILRRK 63
Query: 436 YHDIDQ----TALVGQPLVDIDVQDSEND 510
+ D+ AL+G + DV + E D
Sbjct: 64 IGEEDEEYPVKALIGIIAAE-DVTEEEID 91
Score = 38.7 bits (86), Expect = 0.13
Identities = 27/94 (28%), Positives = 43/94 (45%), Gaps = 4/94 (4%)
Frame = +1
Query: 241 TSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDG 420
T+ A I + G + E I W + GD V+ I EV++DK A + S G
Sbjct: 114 TAAAPEGIYELTMPKWGLTMEEGTISSWLIDEGDEVEVGTEIMEVETDKIAQPVESTVAG 173
Query: 421 IITRLYHDIDQ----TALVGQPLVDIDVQDSEND 510
++ R + D+ AL+G + D V D++ D
Sbjct: 174 VLRRKIGEEDEEYPVKALIG-IIADASVSDADID 206
>UniRef50_A1W7R7 Cluster: Dihydrolipoamide dehydrogenase; n=58;
Bacteria|Rep: Dihydrolipoamide dehydrogenase -
Acidovorax sp. (strain JS42)
Length = 627
Score = 42.7 bits (96), Expect = 0.008
Identities = 34/122 (27%), Positives = 56/122 (45%)
Frame = +1
Query: 262 IVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYH 441
I+ K+ DIG+ EV + E V+ GD ++ ++ V+SDKA++ I S + G++ L
Sbjct: 3 IIDIKVPDIGD-FAEVGVIEVLVQPGDTIRAEQSLVTVESDKASMEIPSSHAGVVKELKV 61
Query: 442 DIDQTALVGQPLVDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRI 621
+ G L+ ++V G A + AP +E K PAV+
Sbjct: 62 KLGDKVAEGSVLLTLEVA----QGAAAPAAAPAAASTPSAPPSES----KPAPAPAVQAP 113
Query: 622 AA 627
AA
Sbjct: 114 AA 115
>UniRef50_Q6CNU8 Cluster: Kluyveromyces lactis strain NRRL Y-1140
chromosome E of strain NRRL Y- 1140 of Kluyveromyces
lactis; n=1; Kluyveromyces lactis|Rep: Kluyveromyces
lactis strain NRRL Y-1140 chromosome E of strain NRRL Y-
1140 of Kluyveromyces lactis - Kluyveromyces lactis
(Yeast) (Candida sphaerica)
Length = 405
Score = 42.7 bits (96), Expect = 0.008
Identities = 25/93 (26%), Positives = 45/93 (48%), Gaps = 2/93 (2%)
Frame = +1
Query: 226 LRHFHTSHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 405
LR H + K AF + + + + +W K GD D + EV++DKA + +
Sbjct: 12 LRQLHQCRTMLKAQAFGMPAMSPTMERGGVVDWKFKAGDTFSAGDVLLEVETDKATIDVE 71
Query: 406 SRYDGIITRLYHDIDQTAL-VGQPLVDI-DVQD 498
++ DG + ++ + + VG+P+ I DV D
Sbjct: 72 AQDDGKLAKILKENGAKDIPVGEPIAYIADVDD 104
>UniRef50_A1WK19 Cluster: Alpha/beta hydrolase fold; n=1;
Verminephrobacter eiseniae EF01-2|Rep: Alpha/beta
hydrolase fold - Verminephrobacter eiseniae (strain
EF01-2)
Length = 440
Score = 35.1 bits (77), Expect(2) = 0.009
Identities = 16/50 (32%), Positives = 29/50 (58%)
Frame = +1
Query: 322 WFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQ 471
W+VK GD V++ + ++++DKA + + + G+I + I T VGQ
Sbjct: 22 WYVKNGDQVRKGQVLFDIETDKATMEVEAPASGVIDSIDGAIGVTMPVGQ 71
Score = 26.6 bits (56), Expect(2) = 0.009
Identities = 14/52 (26%), Positives = 25/52 (48%)
Frame = +1
Query: 511 GKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAAQFKVDLSAVKATG 666
G T ++P P+A A ++ + TP R +A + VDL ++ +G
Sbjct: 109 GHATAMSPPAPMASTAAQLPFRSDGASLRATPLARSLARERGVDLLRLRGSG 160
>UniRef50_Q9RXQ3 Cluster: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component; n=4;
Deinococci|Rep: Pyruvate dehydrogenase complex,
dihydrolipoamide acetyltransferase E2 component -
Deinococcus radiodurans
Length = 617
Score = 42.3 bits (95), Expect = 0.010
Identities = 37/155 (23%), Positives = 64/155 (41%), Gaps = 25/155 (16%)
Frame = +1
Query: 277 LSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQT 456
L D+G+ I + + V VGD V + + E+++DKA V + + G + + I +
Sbjct: 186 LPDVGDNIEKGTVVTILVNVGDTVSEGQPVIELETDKAVVEVPANASGTVQSVAVKIGDS 245
Query: 457 ALVGQPLVDID-----------------VQDSENDGKPTDVAP-DKPVAEIDAPKTEQNQ 582
VG ++ + S+ +P P P A+ AP+ Q
Sbjct: 246 IPVGGTILTLSGAASTQPTAPAPESAQPASQSQQSTQPEPARPAGAPQAQAAAPQQSGTQ 305
Query: 583 KIK-------VLTTPAVRRIAAQFKVDLSAVKATG 666
+ V P+VRR+A + +D+ AV TG
Sbjct: 306 NPQTFDGRPVVPAAPSVRRLAREIGIDIHAVHGTG 340
Score = 39.9 bits (89), Expect = 0.055
Identities = 25/88 (28%), Positives = 42/88 (47%), Gaps = 1/88 (1%)
Frame = +1
Query: 274 KLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQ 453
KL D+G+ I + + V GD+V + I E+++DKA V + + G I + +
Sbjct: 29 KLPDVGDNIEKGTVVTVLVNPGDSVTEGQPIIEIETDKAVVEVPASAAGTIEAVNVKVGD 88
Query: 454 TALVGQPLVDI-DVQDSENDGKPTDVAP 534
T VG + + S +D P+ AP
Sbjct: 89 TIPVGGVIATLGGGAASASDSAPSASAP 116
>UniRef50_Q2GCH9 Cluster: Pyruvate dehydrogenase complex, E2
component, dihydrolipoamide acetyltransferase; n=1;
Neorickettsia sennetsu str. Miyayama|Rep: Pyruvate
dehydrogenase complex, E2 component, dihydrolipoamide
acetyltransferase - Neorickettsia sennetsu (strain
Miyayama)
Length = 403
Score = 42.3 bits (95), Expect = 0.010
Identities = 33/135 (24%), Positives = 62/135 (45%), Gaps = 16/135 (11%)
Frame = +1
Query: 298 IREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTAL-VGQP 474
++E + +W V G+ ++ I E+++DKA + + +G++ ++ + V QP
Sbjct: 14 MKEGTLAKWLVSEGEKIEAGQVIAEIETDKATMEFEAVDEGVLGKILIPAKTAGVKVNQP 73
Query: 475 L-VDIDVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIK--------------VLTTPA 609
+ V +D + E + K DKP + +T KIK V+ TP
Sbjct: 74 IAVLLDDGEGEKELKKFLSTIDKPTVTDNKAETSDGDKIKNNPSSLPADKQQGRVIATPL 133
Query: 610 VRRIAAQFKVDLSAV 654
R+IA+ +DLS +
Sbjct: 134 ARKIASINGIDLSLI 148
>UniRef50_Q1IMV8 Cluster: Dihydrolipoamide acetyltransferase; n=1;
Acidobacteria bacterium Ellin345|Rep: Dihydrolipoamide
acetyltransferase - Acidobacteria bacterium (strain
Ellin345)
Length = 615
Score = 42.3 bits (95), Expect = 0.010
Identities = 32/120 (26%), Positives = 50/120 (41%), Gaps = 1/120 (0%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
FKL ++GE I + VK GD V++ + E+++DKA + + S G + +
Sbjct: 5 FKLPELGENIASGDLVRVMVKPGDTVKEGQPVIELETDKAVIEVPSTVSGKVQEVKVQKG 64
Query: 451 QTALVGQPLVDIDVQDSENDG-KPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPAVRRIAA 627
Q VG + + DG V P P D PK E + P+ + AA
Sbjct: 65 QKLKVGAIIF------TYGDGAAAAPVQPAAPAKTEDKPKAEPKAEAPKQAAPSAAKPAA 118
Score = 38.7 bits (86), Expect = 0.13
Identities = 20/85 (23%), Positives = 40/85 (47%)
Frame = +1
Query: 244 SHAVNKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGI 423
S + + FKL ++GE I++ + K G +V I E+++DKA + + + G
Sbjct: 119 STGTKQTIEFKLPELGENIKQGQLVRIIAKQGASVSDGQPILELETDKAVIEVPATLTGT 178
Query: 424 ITRLYHDIDQTALVGQPLVDIDVQD 498
I ++ VGQ + ++ +
Sbjct: 179 IKEVHVKEGDKIGVGQTIFTVETTE 203
>UniRef50_Q0A5F2 Cluster: Catalytic domain of components of various
dehydrogenase complexes; n=2; Bacteria|Rep: Catalytic
domain of components of various dehydrogenase complexes
- Alkalilimnicola ehrlichei (strain MLHE-1)
Length = 441
Score = 42.3 bits (95), Expect = 0.010
Identities = 30/116 (25%), Positives = 49/116 (42%), Gaps = 4/116 (3%)
Frame = +1
Query: 271 FKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDID 450
F + +G + + EW V+ GD V++ I V+++K A+ + G++ LY +
Sbjct: 4 FLMPSLGADMASGELVEWRVRPGDRVEKGQVIAVVETNKGAIEVEVFESGVVEALYEEPG 63
Query: 451 QTALVGQPLVDI----DVQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTP 606
VG P+ I ++ E KP KP E PK + K K P
Sbjct: 64 TRLPVGAPMARIGDGRGLEAGEGSPKPEPKPEPKPKPE-PKPKPKPKPKPKPKPKP 118
Database: uniref50
Posted date: Oct 5, 2007 11:19 AM
Number of letters in database: 575,637,011
Number of sequences in database: 1,657,284
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 623,302,949
Number of Sequences: 1657284
Number of extensions: 12230540
Number of successful extensions: 39460
Number of sequences better than 10.0: 377
Number of HSP's better than 10.0 without gapping: 37525
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 39347
length of database: 575,637,011
effective HSP length: 98
effective length of database: 413,223,179
effective search space used: 51652897375
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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