Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV19d08f
(671 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein. 145 1e-34
M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylas... 145 1e-34
M19301-1|AAA59200.1| 315|Homo sapiens DBT protein. 145 1e-34
J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched ... 145 1e-34
BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branch... 145 1e-34
BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branch... 145 1e-34
AL445928-10|CAH72258.1| 320|Homo sapiens dihydrolipoamide branc... 145 1e-34
AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branch... 145 1e-34
U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase co... 53 8e-07
Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein. 52 1e-06
BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase ... 52 1e-06
AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing compo... 52 1e-06
AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide dehydr... 52 1e-06
L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide succinyl... 41 0.004
D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide succinyl... 41 0.004
D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial dihydrolipo... 41 0.004
CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein. 41 0.004
BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide S-succ... 41 0.004
BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide S-succ... 41 0.004
AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein. 41 0.004
Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 ... 40 0.011
S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate dehyd... 40 0.011
BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide S-acet... 40 0.011
AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide S-acet... 40 0.011
J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide acetyltr... 39 0.019
BC004214-1|AAH04214.1| 725|Homo sapiens methylcrotonoyl-Coenzym... 35 0.30
BC004187-1|AAH04187.1| 725|Homo sapiens methylcrotonoyl-Coenzym... 35 0.30
AK023051-1|BAB14377.1| 725|Homo sapiens CARBOXYLASE (EC 6.3.4.... 35 0.30
AF310972-1|AAG53095.1| 725|Homo sapiens 3-methylcrotonyl-CoA ca... 35 0.30
AF310339-1|AAG50245.1| 725|Homo sapiens 3-methylcrotonyl-CoA ca... 35 0.30
AF297332-1|AAK67986.1| 725|Homo sapiens 3-methylcrotonyl-CoA ca... 35 0.30
AB209737-1|BAD92974.1| 741|Homo sapiens methylcrotonoyl-Coenzym... 35 0.30
AB029826-1|BAA99407.1| 725|Homo sapiens 3-methylcrotonyl-CoA ca... 35 0.30
AK057516-1|BAB71517.1| 573|Homo sapiens protein ( Homo sapiens ... 31 2.8
AC016689-1|AAX88865.1| 571|Homo sapiens unknown protein. 31 2.8
Z48500-1|CAA88400.1| 273|Homo sapiens human mammary dihydrolipo... 30 6.6
AJ298318-1|CAC83675.1| 1349|Homo sapiens mucin 5 protein. 30 6.6
>X66785-1|CAA47285.1| 482|Homo sapiens transacylase protein.
Length = 482
Score = 145 bits (352), Expect = 1e-34
Identities = 74/140 (52%), Positives = 98/140 (70%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 63 QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 122
Query: 439 HDIDQTALVGQPLVDID---VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
+++D A VG+PLVDI+ ++DSE D + P D ++ + K L TPA
Sbjct: 123 YNLDDIAYVGKPLVDIETEALKDSEED------VVETPAVSHDEHTHQEIKGRKTLATPA 176
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + + LS V +G+
Sbjct: 177 VRRLAMENNIKLSEVVGSGK 196
>M27093-1|AAA64512.1| 477|Homo sapiens dihydrolipoyl transacylase
protein.
Length = 477
Score = 145 bits (352), Expect = 1e-34
Identities = 74/140 (52%), Positives = 98/140 (70%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 58 QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 117
Query: 439 HDIDQTALVGQPLVDID---VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
+++D A VG+PLVDI+ ++DSE D + P D ++ + K L TPA
Sbjct: 118 YNLDDIAYVGKPLVDIETEALKDSEED------VVETPAVSHDEHTHQEIKGRKTLATPA 171
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + + LS V +G+
Sbjct: 172 VRRLAMENNIKLSEVVGSGK 191
>M19301-1|AAA59200.1| 315|Homo sapiens DBT protein.
Length = 315
Score = 145 bits (352), Expect = 1e-34
Identities = 74/140 (52%), Positives = 98/140 (70%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 58 QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 117
Query: 439 HDIDQTALVGQPLVDID---VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
+++D A VG+PLVDI+ ++DSE D + P D ++ + K L TPA
Sbjct: 118 YNLDDIAYVGKPLVDIETEALKDSEED------VVETPAVSHDEHTHQEIKGRKTLATPA 171
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + + LS V +G+
Sbjct: 172 VRRLAMENNIKLSEVVGSGK 191
>J03208-1|AAA35589.1| 477|Homo sapiens protein ( Human branched
chain acyltransferase mRNA, complete cds. ).
Length = 477
Score = 145 bits (352), Expect = 1e-34
Identities = 74/140 (52%), Positives = 98/140 (70%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 58 QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 117
Query: 439 HDIDQTALVGQPLVDID---VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
+++D A VG+PLVDI+ ++DSE D + P D ++ + K L TPA
Sbjct: 118 YNLDDIAYVGKPLVDIETEALKDSEED------VVETPAVSHDEHTHQEIKGRKTLATPA 171
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + + LS V +G+
Sbjct: 172 VRRLAMENNIKLSEVVGSGK 191
>BT007372-1|AAP36036.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase (E2 component of branched chain ke
protein.
Length = 482
Score = 145 bits (352), Expect = 1e-34
Identities = 74/140 (52%), Positives = 98/140 (70%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 63 QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 122
Query: 439 HDIDQTALVGQPLVDID---VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
+++D A VG+PLVDI+ ++DSE D + P D ++ + K L TPA
Sbjct: 123 YNLDDIAYVGKPLVDIETEALKDSEED------VVETPAVSHDEHTHQEIKGRKTLATPA 176
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + + LS V +G+
Sbjct: 177 VRRLAMENNIKLSEVVGSGK 196
>BC016675-1|AAH16675.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 145 bits (352), Expect = 1e-34
Identities = 74/140 (52%), Positives = 98/140 (70%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 63 QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 122
Query: 439 HDIDQTALVGQPLVDID---VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
+++D A VG+PLVDI+ ++DSE D + P D ++ + K L TPA
Sbjct: 123 YNLDDIAYVGKPLVDIETEALKDSEED------VVETPAVSHDEHTHQEIKGRKTLATPA 176
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + + LS V +G+
Sbjct: 177 VRRLAMENNIKLSEVVGSGK 196
>AL445928-10|CAH72258.1| 320|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 320
Score = 145 bits (352), Expect = 1e-34
Identities = 74/140 (52%), Positives = 98/140 (70%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 63 QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 122
Query: 439 HDIDQTALVGQPLVDID---VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
+++D A VG+PLVDI+ ++DSE D + P D ++ + K L TPA
Sbjct: 123 YNLDDIAYVGKPLVDIETEALKDSEED------VVETPAVSHDEHTHQEIKGRKTLATPA 176
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + + LS V +G+
Sbjct: 177 VRRLAMENNIKLSEVVGSGK 196
>AL445928-9|CAH72257.1| 482|Homo sapiens dihydrolipoamide branched
chain transacylase E2 protein.
Length = 482
Score = 145 bits (352), Expect = 1e-34
Identities = 74/140 (52%), Positives = 98/140 (70%), Gaps = 3/140 (2%)
Frame = +1
Query: 259 KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLY 438
++V FKLSDIGEGIREV +KEW+VK GD V QFD+ICEVQSDKA+VTITSRYDG+I +LY
Sbjct: 63 QVVQFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLY 122
Query: 439 HDIDQTALVGQPLVDID---VQDSENDGKPTDVAPDKPVAEIDAPKTEQNQKIKVLTTPA 609
+++D A VG+PLVDI+ ++DSE D + P D ++ + K L TPA
Sbjct: 123 YNLDDIAYVGKPLVDIETEALKDSEED------VVETPAVSHDEHTHQEIKGRKTLATPA 176
Query: 610 VRRIAAQFKVDLSAVKATGR 669
VRR+A + + LS V +G+
Sbjct: 177 VRRLAMENNIKLSEVVGSGK 196
>U82328-1|AAC39661.1| 501|Homo sapiens pyruvate dehydrogenase
complex protein X subunit precursor protein.
Length = 501
Score = 53.2 bits (122), Expect = 8e-07
Identities = 43/170 (25%), Positives = 76/170 (44%), Gaps = 18/170 (10%)
Frame = +1
Query: 211 SLSKELRHFHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDK 387
S + R FH++ + + + + + E I +W K G+ V D +CE+++DK
Sbjct: 38 SRGRNWRWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDK 97
Query: 388 AAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGK----PTDVAPDKPVAEI 555
A VT+ + DGI+ ++ + + L+ + V++ E D K P DV P PV++
Sbjct: 98 AVVTLDASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGE-DWKHVEIPKDVGPPPPVSKP 156
Query: 556 DAPKTEQNQKIKV-------------LTTPAVRRIAAQFKVDLSAVKATG 666
P+ +I + +PA R I + +D S ATG
Sbjct: 157 SEPRPSPEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATG 206
>Y13145-1|CAA73606.1| 501|Homo sapiens protein X protein.
Length = 501
Score = 52.4 bits (120), Expect = 1e-06
Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 18/164 (10%)
Frame = +1
Query: 229 RHFHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 405
R FH++ + + + + + E I +W K G+ V D +CE+++DKA VT+
Sbjct: 44 RWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLD 103
Query: 406 SRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGK----PTDVAPDKPVAEIDAPKTE 573
+ DGI+ ++ + + L+ + V++ E D K P DV P PV++ P+
Sbjct: 104 ASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGE-DWKHVEIPKDVGPPPPVSKPSEPRPS 162
Query: 574 QNQKIKV-------------LTTPAVRRIAAQFKVDLSAVKATG 666
+I + +PA R I + +D S ATG
Sbjct: 163 PEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATG 206
>BC010389-1|AAH10389.1| 501|Homo sapiens pyruvate dehydrogenase
complex, component X protein.
Length = 501
Score = 52.4 bits (120), Expect = 1e-06
Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 18/164 (10%)
Frame = +1
Query: 229 RHFHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 405
R FH++ + + + + + E I +W K G+ V D +CE+++DKA VT+
Sbjct: 44 RWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLD 103
Query: 406 SRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGK----PTDVAPDKPVAEIDAPKTE 573
+ DGI+ ++ + + L+ + V++ E D K P DV P PV++ P+
Sbjct: 104 ASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGE-DWKHVEIPKDVGPPPPVSKPSEPRPS 162
Query: 574 QNQKIKV-------------LTTPAVRRIAAQFKVDLSAVKATG 666
+I + +PA R I + +D S ATG
Sbjct: 163 PEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATG 206
>AJ298105-1|CAC18649.1| 501|Homo sapiens lipoyl-containing
component X protein.
Length = 501
Score = 52.4 bits (120), Expect = 1e-06
Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 18/164 (10%)
Frame = +1
Query: 229 RHFHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 405
R FH++ + + + + + E I +W K G+ V D +CE+++DKA VT+
Sbjct: 44 RWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLD 103
Query: 406 SRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGK----PTDVAPDKPVAEIDAPKTE 573
+ DGI+ ++ + + L+ + V++ E D K P DV P PV++ P+
Sbjct: 104 ASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGE-DWKHVEIPKDVGPPPPVSKPSEPRPS 162
Query: 574 QNQKIKV-------------LTTPAVRRIAAQFKVDLSAVKATG 666
+I + +PA R I + +D S ATG
Sbjct: 163 PEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATG 206
>AF001437-1|AAB66315.1| 501|Homo sapiens dihydrolipoamide
dehydrogenase-binding protein protein.
Length = 501
Score = 52.4 bits (120), Expect = 1e-06
Identities = 42/164 (25%), Positives = 74/164 (45%), Gaps = 18/164 (10%)
Frame = +1
Query: 229 RHFHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDNICEVQSDKAAVTIT 405
R FH++ + + + + + E I +W K G+ V D +CE+++DKA VT+
Sbjct: 44 RWFHSTQWLRGDPIKILMPSLSPTMEEGNIVKWLKKEGEAVSAGDALCEIETDKAVVTLD 103
Query: 406 SRYDGIITRLYHDIDQTALVGQPLVDIDVQDSENDGK----PTDVAPDKPVAEIDAPKTE 573
+ DGI+ ++ + + L+ + V++ E D K P DV P PV++ P+
Sbjct: 104 ASDDGILAKIVVEEGSKNIRLGSLIGLIVEEGE-DWKHVEIPKDVGPPPPVSKPSEPRPS 162
Query: 574 QNQKIKV-------------LTTPAVRRIAAQFKVDLSAVKATG 666
+I + +PA R I + +D S ATG
Sbjct: 163 PEPQISIPVKKEHIPGTLRFRLSPAARNILEKHSLDASQGTATG 206
>L37418-1|AAB59629.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +1
Query: 187 SYKTPLNESLSKELRHFHTSHAV-NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDN 363
S K +N S+ +R F T+ + +V K E + E ++ W VGD V + +
Sbjct: 45 SRKVVINNSVFS-VRFFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEV 102
Query: 364 ICEVQSDKAAVTITSRYDGIITRL 435
+CE+++DK +V + S +G+I L
Sbjct: 103 VCEIETDKTSVQVPSPANGVIEAL 126
>D26535-1|BAA05536.1| 453|Homo sapiens dihydrolipoamide
succinyltransferase protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +1
Query: 187 SYKTPLNESLSKELRHFHTSHAV-NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDN 363
S K +N S+ +R F T+ + +V K E + E ++ W VGD V + +
Sbjct: 45 SRKVVINNSVFS-VRFFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEV 102
Query: 364 ICEVQSDKAAVTITSRYDGIITRL 435
+CE+++DK +V + S +G+I L
Sbjct: 103 VCEIETDKTSVQVPSPANGVIEAL 126
>D16373-1|BAA03871.1| 453|Homo sapiens mitochondrial
dihydrolipoamide succinyltransferase protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +1
Query: 187 SYKTPLNESLSKELRHFHTSHAV-NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDN 363
S K +N S+ +R F T+ + +V K E + E ++ W VGD V + +
Sbjct: 45 SRKVVINNSVFS-VRFFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEV 102
Query: 364 ICEVQSDKAAVTITSRYDGIITRL 435
+CE+++DK +V + S +G+I L
Sbjct: 103 VCEIETDKTSVQVPSPANGVIEAL 126
>CR456727-1|CAG33008.1| 453|Homo sapiens DLST protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +1
Query: 187 SYKTPLNESLSKELRHFHTSHAV-NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDN 363
S K +N S+ +R F T+ + +V K E + E ++ W VGD V + +
Sbjct: 45 SRKVVINNSVFS-VRFFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEV 102
Query: 364 ICEVQSDKAAVTITSRYDGIITRL 435
+CE+++DK +V + S +G+I L
Sbjct: 103 VCEIETDKTSVQVPSPANGVIEAL 126
>BC001922-1|AAH01922.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +1
Query: 187 SYKTPLNESLSKELRHFHTSHAV-NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDN 363
S K +N S+ +R F T+ + +V K E + E ++ W VGD V + +
Sbjct: 45 SRKVVINNSVFS-VRFFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEV 102
Query: 364 ICEVQSDKAAVTITSRYDGIITRL 435
+CE+++DK +V + S +G+I L
Sbjct: 103 VCEIETDKTSVQVPSPANGVIEAL 126
>BC000302-1|AAH00302.1| 453|Homo sapiens dihydrolipoamide
S-succinyltransferase (E2 component of 2-oxo-glutarate
complex protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +1
Query: 187 SYKTPLNESLSKELRHFHTSHAV-NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDN 363
S K +N S+ +R F T+ + +V K E + E ++ W VGD V + +
Sbjct: 45 SRKVVINNSVFS-VRFFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEV 102
Query: 364 ICEVQSDKAAVTITSRYDGIITRL 435
+CE+++DK +V + S +G+I L
Sbjct: 103 VCEIETDKTSVQVPSPANGVIEAL 126
>AC006530-2|AAD30181.1| 453|Homo sapiens alpha-KG-E2 protein.
Length = 453
Score = 41.1 bits (92), Expect = 0.004
Identities = 25/84 (29%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Frame = +1
Query: 187 SYKTPLNESLSKELRHFHTSHAV-NKIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDN 363
S K +N S+ +R F T+ + +V K E + E ++ W VGD V + +
Sbjct: 45 SRKVVINNSVFS-VRFFRTTAVCKDDLVTVKTPAFAESVTEGDVR-WEKAVGDTVAEDEV 102
Query: 364 ICEVQSDKAAVTITSRYDGIITRL 435
+CE+++DK +V + S +G+I L
Sbjct: 103 VCEIETDKTSVQVPSPANGVIEAL 126
>Y00978-1|CAA68787.1| 615|Homo sapiens PDC-E2 precursor (AA -54 to
561) protein.
Length = 615
Score = 39.5 bits (88), Expect = 0.011
Identities = 35/145 (24%), Positives = 67/145 (46%), Gaps = 27/145 (18%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDID 489
++ W KVG+ + + D + E+++DKA + + +G + + L + + +G PL I
Sbjct: 203 VQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIV 262
Query: 490 VQDSE----NDGKPTDVAPDK---------PVAEI-------------DAPKTEQNQKIK 591
++++ D +PT+V K PVA + P T K +
Sbjct: 263 EKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGR 322
Query: 592 VLTTPAVRRIAAQFKVDLSAVKATG 666
V +P +++A + +DL+ VK TG
Sbjct: 323 VFVSPLAKKLAVEKGIDLTQVKGTG 347
Score = 30.3 bits (65), Expect = 6.6
Identities = 14/32 (43%), Positives = 18/32 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
I W K GD + + D I EV++DKA V S
Sbjct: 76 IARWKKKEGDKINEGDLIAEVETDKATVGFES 107
>S72422-1|AAB31066.1| 451|Homo sapiens alpha-ketoglutarate
dehydrogenase complex dihydrolipoyl succinyltransferase
protein.
Length = 451
Score = 39.5 bits (88), Expect = 0.011
Identities = 25/85 (29%), Positives = 43/85 (50%), Gaps = 1/85 (1%)
Frame = +1
Query: 187 SYKTPLNESLSKELRHFHTSHAVN-KIVAFKLSDIGEGIREVVIKEWFVKVGDNVQQFDN 363
S K +N S+ +R F T+ +V K E + E ++ W VGD V + +
Sbjct: 44 SRKVVINNSVFS-VRFFRTTTVCKYDLVTVKTPAFAEPVTEGDVR-WEKAVGDTVAEDEV 101
Query: 364 ICEVQSDKAAVTITSRYDGIITRLY 438
+CE+++DK V + S +G+I L+
Sbjct: 102 VCEIETDKTLVQVPSPANGMIEALF 126
>BC039084-1|AAH39084.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 39.5 bits (88), Expect = 0.011
Identities = 35/145 (24%), Positives = 67/145 (46%), Gaps = 27/145 (18%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDID 489
++ W KVG+ + + D + E+++DKA + + +G + + L + + +G PL I
Sbjct: 235 VQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIV 294
Query: 490 VQDSE----NDGKPTDVAPDK---------PVAEI-------------DAPKTEQNQKIK 591
++++ D +PT+V K PVA + P T K +
Sbjct: 295 EKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGR 354
Query: 592 VLTTPAVRRIAAQFKVDLSAVKATG 666
V +P +++A + +DL+ VK TG
Sbjct: 355 VFVSPLAKKLAVEKGIDLTQVKGTG 379
Score = 30.3 bits (65), Expect = 6.6
Identities = 14/32 (43%), Positives = 18/32 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
I W K GD + + D I EV++DKA V S
Sbjct: 108 IARWEKKEGDKINEGDLIAEVETDKATVGFES 139
>AK223596-1|BAD97316.1| 647|Homo sapiens dihydrolipoamide
S-acetyltransferase (E2 component of pyruvate
dehydrogenase co protein.
Length = 647
Score = 39.5 bits (88), Expect = 0.011
Identities = 34/145 (23%), Positives = 65/145 (44%), Gaps = 27/145 (18%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDID 489
++ W KVG+ + + D + E+++DKA + + +G + + L + + +G PL I
Sbjct: 235 VQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIV 294
Query: 490 VQDSE----NDGKPTDVAPDKPVA----------------------EIDAPKTEQNQKIK 591
++++ D +PT+V KP A P T K +
Sbjct: 295 EKEADISAFADYRPTEVTDLKPQAPPPTPPPVAAVPPTPQPLAPTPSAPCPATPAGPKGR 354
Query: 592 VLTTPAVRRIAAQFKVDLSAVKATG 666
V +P +++A + +DL+ VK TG
Sbjct: 355 VFVSPLAKKLAVEKGIDLTQVKGTG 379
Score = 30.3 bits (65), Expect = 6.6
Identities = 14/32 (43%), Positives = 18/32 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
I W K GD + + D I EV++DKA V S
Sbjct: 108 IARWEKKEGDKINEGDLIAEVETDKATVGFES 139
>J03866-1|AAA62253.1| 613|Homo sapiens dihydrolipoamide
acetyltransferase protein.
Length = 613
Score = 38.7 bits (86), Expect = 0.019
Identities = 35/145 (24%), Positives = 66/145 (45%), Gaps = 27/145 (18%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITR-LYHDIDQTALVGQPLVDID 489
++ W KVG+ + + D + E+++DKA + + +G + + L + + +G PL I
Sbjct: 202 VQRWEKKVGEKLSEGDLLAEIETDKATIGFEVQEEGYLAKILVPEGTRDVPLGTPLCIIV 261
Query: 490 VQDSE----NDGKPTDVAPDK---------PVAEI-------------DAPKTEQNQKIK 591
++++ D +PT+V K PVA + P T K +
Sbjct: 262 EKEADISAFADYRPTEVTDLKPQVPPPTPPPVAAVPPTPQPLAPTPSTPCPATPAGPKGR 321
Query: 592 VLTTPAVRRIAAQFKVDLSAVKATG 666
V P +++A + +DL+ VK TG
Sbjct: 322 VFVDPLAKKLAVEKGIDLTQVKGTG 346
Score = 30.3 bits (65), Expect = 6.6
Identities = 14/32 (43%), Positives = 18/32 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
I W K GD + + D I EV++DKA V S
Sbjct: 75 IARWEKKEGDKINEGDLIAEVETDKATVGFES 106
>BC004214-1|AAH04214.1| 725|Homo sapiens methylcrotonoyl-Coenzyme A
carboxylase 1 (alpha) protein.
Length = 725
Score = 34.7 bits (76), Expect = 0.30
Identities = 19/64 (29%), Positives = 36/64 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I++ FVK GD V+ D++ + + K TI S DG + ++++ A PLV+ +
Sbjct: 657 IEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEE 716
Query: 493 QDSE 504
++S+
Sbjct: 717 EESD 720
>BC004187-1|AAH04187.1| 725|Homo sapiens methylcrotonoyl-Coenzyme A
carboxylase 1 (alpha) protein.
Length = 725
Score = 34.7 bits (76), Expect = 0.30
Identities = 19/64 (29%), Positives = 36/64 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I++ FVK GD V+ D++ + + K TI S DG + ++++ A PLV+ +
Sbjct: 657 IEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEE 716
Query: 493 QDSE 504
++S+
Sbjct: 717 EESD 720
>AK023051-1|BAB14377.1| 725|Homo sapiens CARBOXYLASE (EC
6.3.4.14); BIOTIN CARBOXYL protein.
Length = 725
Score = 34.7 bits (76), Expect = 0.30
Identities = 19/64 (29%), Positives = 36/64 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I++ FVK GD V+ D++ + + K TI S DG + ++++ A PLV+ +
Sbjct: 657 IEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEE 716
Query: 493 QDSE 504
++S+
Sbjct: 717 EESD 720
>AF310972-1|AAG53095.1| 725|Homo sapiens 3-methylcrotonyl-CoA
carboxylase alpha subunit protein.
Length = 725
Score = 34.7 bits (76), Expect = 0.30
Identities = 19/64 (29%), Positives = 36/64 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I++ FVK GD V+ D++ + + K TI S DG + ++++ A PLV+ +
Sbjct: 657 IEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEE 716
Query: 493 QDSE 504
++S+
Sbjct: 717 EESD 720
>AF310339-1|AAG50245.1| 725|Homo sapiens 3-methylcrotonyl-CoA
carboxylase alpha subunit protein.
Length = 725
Score = 34.7 bits (76), Expect = 0.30
Identities = 19/64 (29%), Positives = 36/64 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I++ FVK GD V+ D++ + + K TI S DG + ++++ A PLV+ +
Sbjct: 657 IEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEE 716
Query: 493 QDSE 504
++S+
Sbjct: 717 EESD 720
>AF297332-1|AAK67986.1| 725|Homo sapiens 3-methylcrotonyl-CoA
carboxylase biotin-containing subunit protein.
Length = 725
Score = 34.7 bits (76), Expect = 0.30
Identities = 19/64 (29%), Positives = 36/64 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I++ FVK GD V+ D++ + + K TI S DG + ++++ A PLV+ +
Sbjct: 657 IEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEE 716
Query: 493 QDSE 504
++S+
Sbjct: 717 EESD 720
>AB209737-1|BAD92974.1| 741|Homo sapiens methylcrotonoyl-Coenzyme A
carboxylase 1 (alpha) variant protein.
Length = 741
Score = 34.7 bits (76), Expect = 0.30
Identities = 19/64 (29%), Positives = 36/64 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I++ FVK GD V+ D++ + + K TI S DG + ++++ A PLV+ +
Sbjct: 673 IEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEE 732
Query: 493 QDSE 504
++S+
Sbjct: 733 EESD 736
>AB029826-1|BAA99407.1| 725|Homo sapiens 3-methylcrotonyl-CoA
carboxylase biotin-containing subunit protein.
Length = 725
Score = 34.7 bits (76), Expect = 0.30
Identities = 19/64 (29%), Positives = 36/64 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITSRYDGIITRLYHDIDQTALVGQPLVDIDV 492
I++ FVK GD V+ D++ + + K TI S DG + ++++ A PLV+ +
Sbjct: 657 IEKVFVKAGDKVKAGDSLMVMIAMKMEHTIKSPKDGTVKKVFYREGAQANRHTPLVEFEE 716
Query: 493 QDSE 504
++S+
Sbjct: 717 EESD 720
>AK057516-1|BAB71517.1| 573|Homo sapiens protein ( Homo sapiens
cDNA FLJ32954 fis, clone TESTI2008139. ).
Length = 573
Score = 31.5 bits (68), Expect = 2.8
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -1
Query: 131 FTVLSWNTDLRTRIDIAMKELRTRILNNYKEHDASPVFG 15
F+ S NTD + I I+ E T+ N++ + SP FG
Sbjct: 162 FSKTSSNTDAKKHITISAPEYNTKNFKNFETNTTSPAFG 200
>AC016689-1|AAX88865.1| 571|Homo sapiens unknown protein.
Length = 571
Score = 31.5 bits (68), Expect = 2.8
Identities = 14/39 (35%), Positives = 21/39 (53%)
Frame = -1
Query: 131 FTVLSWNTDLRTRIDIAMKELRTRILNNYKEHDASPVFG 15
F+ S NTD + I I+ E T+ N++ + SP FG
Sbjct: 162 FSKTSSNTDAKKHITISAPEYNTKNFKNFETNTTSPAFG 200
>Z48500-1|CAA88400.1| 273|Homo sapiens human mammary
dihydrolipoamide acetyltransferase,r protein.
Length = 273
Score = 30.3 bits (65), Expect = 6.6
Identities = 14/32 (43%), Positives = 18/32 (56%)
Frame = +1
Query: 313 IKEWFVKVGDNVQQFDNICEVQSDKAAVTITS 408
I W K GD + + D I EV++DKA V S
Sbjct: 53 IARWEKKEGDKINEGDLIAEVETDKATVGFES 84
>AJ298318-1|CAC83675.1| 1349|Homo sapiens mucin 5 protein.
Length = 1349
Score = 30.3 bits (65), Expect = 6.6
Identities = 29/99 (29%), Positives = 45/99 (45%), Gaps = 1/99 (1%)
Frame = -1
Query: 560 ASISATGLSGATSVGFPSFSESCTSI-STRGCPTRAV*SISWYSRVMIPSYRLVMVTAAL 384
+SI++T + TS P+ S + SI ST PT + S S P+ T+
Sbjct: 638 SSITSTTQTSTTSA--PTTSTTPASIPSTTSAPTTSTTSAPTTSTTSAPT---TSTTSTP 692
Query: 383 SLCTSQMLSNC*TLSPTLTNHSLMTTSRIPSPISESLKA 267
TS ++ T +PT + S TTS I +P + + A
Sbjct: 693 QTTTSSAPTSSTTSAPTTSTISAPTTSTISAPTTSTTSA 731
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 86,909,567
Number of Sequences: 237096
Number of extensions: 1686320
Number of successful extensions: 3885
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 3707
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3872
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7647512560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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