Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV19b09f
(782 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 242 1e-63
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 242 1e-63
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 242 1e-63
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 228 2e-59
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 219 9e-57
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 219 9e-57
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 219 9e-57
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 219 9e-57
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 219 9e-57
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 219 1e-56
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 206 5e-53
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 206 7e-53
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 206 7e-53
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 206 7e-53
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 206 7e-53
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 190 6e-48
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 190 6e-48
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 190 6e-48
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 190 6e-48
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 102 1e-21
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 102 1e-21
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 101 2e-21
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 94 6e-19
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 242 bits (592), Expect = 1e-63
Identities = 110/208 (52%), Positives = 146/208 (70%), Gaps = 1/208 (0%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP+GF++ AA+A+YQIEGAW DGK +IWD H P V +++ GD+A DSY D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAED 1435
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ ++ LGV +YRFS+SW+RILP YINEAG+ YY LID LL +I+P +TIYHWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD+GGW N I+ + +YA VLFQ+ GD+VK WIT+NEP I +QGY GT AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 649 YT-MSGVADYLCGKNVLLAHAKAYHIYD 729
+ G A Y+ G N++ AHA+A+H+Y+
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYN 1583
Score = 228 bits (557), Expect = 2e-59
Identities = 106/208 (50%), Positives = 132/208 (63%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
F FL+G ++++YQIEGAW+ DGK +IWD H S V DN+TGDIA DSY D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ M+R L V YRFS+SW+RI PT IN GV YYN LI+ L+ NI PM+T++HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD+GGW NP +ID + YA FQ FGDRVK W+T NEP + + GY G P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYDK 732
G A Y V+ AHA+ YH YD+
Sbjct: 1083 VKDPGWAPYRIAHTVIKAHARVYHTYDE 1110
Score = 188 bits (459), Expect = 1e-47
Identities = 88/209 (42%), Positives = 123/209 (58%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP+GFL+GA+T ++ +EG W G+ +IWD + + +T ++A+DSY D
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASD 439
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
V ++ L Y+FS+SW+RI P + GVAYYN LID L IEPM T++HWD
Sbjct: 440 VALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWD 499
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD GGW N ++D + DYA F FGDRVK W+T +EP + + GY G P
Sbjct: 500 LPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPG 559
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYDKN 735
+ GVA + VL AHA+ +H Y+ +
Sbjct: 560 ISDPGVASFKVAHLVLKAHARTWHHYNSH 588
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/99 (29%), Positives = 48/99 (48%)
Frame = +1
Query: 313 VDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWDLPQKLQDM 492
+ +Y+ +SW ++LP +E V Y L+ L ++PM+ ++H LP
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRR 143
Query: 493 GGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEI 609
T + D +ADYA F FGD V W T ++ +E+
Sbjct: 144 ---TEAF-ADLFADYATFAFHSFGDLVGIWFTFSDLEEV 178
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 242 bits (592), Expect = 1e-63
Identities = 110/208 (52%), Positives = 146/208 (70%), Gaps = 1/208 (0%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP+GF++ AA+A+YQIEGAW DGK +IWD H P V +++ GD+A DSY D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAED 1435
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ ++ LGV +YRFS+SW+RILP YINEAG+ YY LID LL +I+P +TIYHWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD+GGW N I+ + +YA VLFQ+ GD+VK WIT+NEP I +QGY GT AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 649 YT-MSGVADYLCGKNVLLAHAKAYHIYD 729
+ G A Y+ G N++ AHA+A+H+Y+
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYN 1583
Score = 227 bits (555), Expect = 3e-59
Identities = 106/208 (50%), Positives = 132/208 (63%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
F FL+G ++++YQIEGAW+ DGK +IWD H S V DN+TGDIA DSY D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ M+R L V YRFS+SW+RI PT IN GV YYN LI+ L+ NI PM+T++HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD+GGW NP +ID + YA FQ FGDRVK W+T NEP + + GY G P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYDK 732
G A Y V+ AHA+ YH YD+
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDE 1110
Score = 188 bits (459), Expect = 1e-47
Identities = 88/209 (42%), Positives = 123/209 (58%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP+GFL+GA+T ++ +EG W G+ +IWD + + +T ++A+DSY D
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASD 439
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
V ++ L Y+FS+SW+RI P + GVAYYN LID L IEPM T++HWD
Sbjct: 440 VALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWD 499
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD GGW N ++D + DYA F FGDRVK W+T +EP + + GY G P
Sbjct: 500 LPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPG 559
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYDKN 735
+ GVA + VL AHA+ +H Y+ +
Sbjct: 560 ISDPGVASFKVAHLVLKAHARTWHHYNSH 588
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/99 (29%), Positives = 48/99 (48%)
Frame = +1
Query: 313 VDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWDLPQKLQDM 492
+ +Y+ +SW ++LP +E V Y L+ L ++PM+ ++H LP
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRR 143
Query: 493 GGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEI 609
T + D +ADYA F FGD V W T ++ +E+
Sbjct: 144 ---TEAF-ADLFADYATFAFHSFGDLVGIWFTFSDLEEV 178
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 242 bits (592), Expect = 1e-63
Identities = 110/208 (52%), Positives = 146/208 (70%), Gaps = 1/208 (0%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP+GF++ AA+A+YQIEGAW DGK +IWD H P V +++ GD+A DSY D
Sbjct: 1377 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAED 1435
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ ++ LGV +YRFS+SW+RILP YINEAG+ YY LID LL +I+P +TIYHWD
Sbjct: 1436 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 1495
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD+GGW N I+ + +YA VLFQ+ GD+VK WIT+NEP I +QGY GT AP
Sbjct: 1496 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPG 1555
Query: 649 YT-MSGVADYLCGKNVLLAHAKAYHIYD 729
+ G A Y+ G N++ AHA+A+H+Y+
Sbjct: 1556 VSNRPGTAPYIVGHNLIKAHAEAWHLYN 1583
Score = 227 bits (555), Expect = 3e-59
Identities = 106/208 (50%), Positives = 132/208 (63%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
F FL+G ++++YQIEGAW+ DGK +IWD H S V DN+TGDIA DSY D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ M+R L V YRFS+SW+RI PT IN GV YYN LI+ L+ NI PM+T++HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD+GGW NP +ID + YA FQ FGDRVK W+T NEP + + GY G P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYDK 732
G A Y V+ AHA+ YH YD+
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDE 1110
Score = 188 bits (459), Expect = 1e-47
Identities = 88/209 (42%), Positives = 123/209 (58%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP+GFL+GA+T ++ +EG W G+ +IWD + + +T ++A+DSY D
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP--RRPLNTTEGQATLEVASDSYHKVASD 439
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
V ++ L Y+FS+SW+RI P + GVAYYN LID L IEPM T++HWD
Sbjct: 440 VALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHWD 499
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD GGW N ++D + DYA F FGDRVK W+T +EP + + GY G P
Sbjct: 500 LPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQHPPG 559
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYDKN 735
+ GVA + VL AHA+ +H Y+ +
Sbjct: 560 ISDPGVASFKVAHLVLKAHARTWHHYNSH 588
Score = 54.8 bits (126), Expect = 3e-07
Identities = 29/99 (29%), Positives = 48/99 (48%)
Frame = +1
Query: 313 VDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWDLPQKLQDM 492
+ +Y+ +SW ++LP +E V Y L+ L ++PM+ ++H LP
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRR 143
Query: 493 GGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEI 609
T + D +ADYA F FGD V W T ++ +E+
Sbjct: 144 ---TEAF-ADLFADYATFAFHSFGDLVGIWFTFSDLEEV 178
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 228 bits (557), Expect = 2e-59
Identities = 106/208 (50%), Positives = 132/208 (63%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
F FL+G ++++YQIEGAW+ DGK +IWD H S V DN+TGDIA DSY D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ M+R L V YRFS+SW+RI PT IN GV YYN LI+ L+ NI PM+T++HWD
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 454
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD+GGW NP +ID + YA FQ FGDRVK W+T NEP + + GY G P
Sbjct: 455 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 514
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYDK 732
G A Y V+ AHA+ YH YD+
Sbjct: 515 VKDPGWAPYRIAHTVIKAHARVYHTYDE 542
Score = 220 bits (537), Expect = 5e-57
Identities = 99/181 (54%), Positives = 128/181 (70%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP+GF++ AA+A+YQIEGAW DGK +IWD H P V +++ GD+A DSY D
Sbjct: 809 FPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSH-TPLRVENDAIGDVACDSYHKIAED 867
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ ++ LGV +YRFS+SW+RILP YINEAG+ YY LID LL +I+P +TIYHWD
Sbjct: 868 LVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHWD 927
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ LQD+GGW N I+ + +YA VLFQ+ GD+VK WIT+NEP I +QGY GT AP
Sbjct: 928 LPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAPV 987
Query: 649 Y 651
+
Sbjct: 988 H 988
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 219 bits (535), Expect = 9e-57
Identities = 94/207 (45%), Positives = 134/207 (64%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYD 729
G Y N++ AHA+++H YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 219 bits (535), Expect = 9e-57
Identities = 94/207 (45%), Positives = 134/207 (64%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYD 729
G Y N++ AHA+++H YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 219 bits (535), Expect = 9e-57
Identities = 94/207 (45%), Positives = 134/207 (64%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYD 729
G Y N++ AHA+++H YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 219 bits (535), Expect = 9e-57
Identities = 94/207 (45%), Positives = 134/207 (64%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYD 729
G Y N++ AHA+++H YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 219 bits (535), Expect = 9e-57
Identities = 94/207 (45%), Positives = 134/207 (64%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYD 729
G Y N++ AHA+++H YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 219 bits (534), Expect = 1e-56
Identities = 94/207 (45%), Positives = 134/207 (64%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
++ I++LG+ +YRFS+SW+R+LP +IN+ G+ YYN +ID+LLK + P++T+YH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 469 LPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAPA 648
LPQ L+D GGW + II+ + YA+ F FGDRVK WITINE + Y +G P
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 649 YTMSGVADYLCGKNVLLAHAKAYHIYD 729
G Y N++ AHA+++H YD
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYD 209
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 206 bits (504), Expect = 5e-53
Identities = 91/209 (43%), Positives = 135/209 (64%), Gaps = 2/209 (0%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP GF +G +++YQ EGAW+ DGK +IWD H V N T D+A D Y + D
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSF-PDYINEAGVAYYNNLIDELLKYNIEPMLTIYHW 465
+ ++REL V++YRFS+SW R+LPT + +N+ G+ +Y++LID LL NI P++T++HW
Sbjct: 97 IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156
Query: 466 DLPQKLQ-DMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLA 642
DLPQ LQ GGW N + +++ DYA + F+ FGDRVK+WIT ++P+ + +GY G A
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHA 216
Query: 643 PAYTMSGVADYLCGKNVLLAHAKAYHIYD 729
P + G Y +++ AHAK +H Y+
Sbjct: 217 PGLKLRGTGLYKAAHHIIKAHAKTWHSYN 245
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 206 bits (503), Expect = 7e-53
Identities = 98/223 (43%), Positives = 133/223 (59%), Gaps = 16/223 (7%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADN---------------S 243
FP GFL+ +A+YQ EG W GK +IWD H +P D+ +
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 244 TGDIANDSYKLYKRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDEL 423
TGD+A+DSY RD E +RELGV +YRFS+SW R+LP N G+ YY L++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 424 LKYNIEPMLTIYHWDLPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEP 600
+ ++P++T+YHWDLPQ+LQD GGW N + D + DYA + F+ FG +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 601 KEICFQGYAIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYD 729
+ + GYA G LAP S YL N+LLAHAK +H+Y+
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 93.9 bits (223), Expect = 6e-19
Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 5/153 (3%)
Frame = +1
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY--- 459
+ +++E+ V ++RFS+ W ILP +N + YY + EL++ NI P++ ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 460 --HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIG 633
+ LP+ L G W NPY +A+YAR+ FQ+ G VK WIT+NEP
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP----------- 690
Query: 634 TLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDK 732
YT + Y G N+L AHA A+H+Y++
Sbjct: 691 -----YTRN--MTYSAGHNLLKAHALAWHVYNE 716
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 206 bits (503), Expect = 7e-53
Identities = 98/223 (43%), Positives = 133/223 (59%), Gaps = 16/223 (7%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADN---------------S 243
FP GFL+ +A+YQ EG W GK +IWD H +P D+ +
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 244 TGDIANDSYKLYKRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDEL 423
TGD+A+DSY RD E +RELGV +YRFS+SW R+LP N G+ YY L++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 424 LKYNIEPMLTIYHWDLPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEP 600
+ ++P++T+YHWDLPQ+LQD GGW N + D + DYA + F+ FG +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 601 KEICFQGYAIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYD 729
+ + GYA G LAP S YL N+LLAHAK +H+Y+
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 206 bits (503), Expect = 7e-53
Identities = 98/223 (43%), Positives = 133/223 (59%), Gaps = 16/223 (7%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADN---------------S 243
FP GFL+ +A+YQ EG W GK +IWD H +P D+ +
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 244 TGDIANDSYKLYKRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDEL 423
TGD+A+DSY RD E +RELGV +YRFS+SW R+LP N G+ YY L++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 424 LKYNIEPMLTIYHWDLPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEP 600
+ ++P++T+YHWDLPQ+LQD GGW N + D + DYA + F+ FG +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 601 KEICFQGYAIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYD 729
+ + GYA G LAP S YL N+LLAHAK +H+Y+
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 93.9 bits (223), Expect = 6e-19
Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 5/153 (3%)
Frame = +1
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY--- 459
+ +++E+ V ++RFS+ W ILP +N + YY + EL++ NI P++ ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 460 --HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIG 633
+ LP+ L G W NPY +A+YAR+ FQ+ G VK WIT+NEP
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP----------- 690
Query: 634 TLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDK 732
YT + Y G N+L AHA A+H+Y++
Sbjct: 691 -----YTRN--MTYSAGHNLLKAHALAWHVYNE 716
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 206 bits (503), Expect = 7e-53
Identities = 98/223 (43%), Positives = 133/223 (59%), Gaps = 16/223 (7%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADN---------------S 243
FP GFL+ +A+YQ EG W GK +IWD H +P D+ +
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 244 TGDIANDSYKLYKRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDEL 423
TGD+A+DSY RD E +RELGV +YRFS+SW R+LP N G+ YY L++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 424 LKYNIEPMLTIYHWDLPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEP 600
+ ++P++T+YHWDLPQ+LQD GGW N + D + DYA + F+ FG +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 601 KEICFQGYAIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYD 729
+ + GYA G LAP S YL N+LLAHAK +H+Y+
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 93.9 bits (223), Expect = 6e-19
Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 5/153 (3%)
Frame = +1
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY--- 459
+ +++E+ V ++RFS+ W ILP +N + YY + EL++ NI P++ ++
Sbjct: 582 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 641
Query: 460 --HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIG 633
+ LP+ L G W NPY +A+YAR+ FQ+ G VK WIT+NEP
Sbjct: 642 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP----------- 690
Query: 634 TLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDK 732
YT + Y G N+L AHA A+H+Y++
Sbjct: 691 -----YTRN--MTYSAGHNLLKAHALAWHVYNE 716
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 190 bits (462), Expect = 6e-48
Identities = 92/213 (43%), Positives = 124/213 (58%), Gaps = 16/213 (7%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADN---------------S 243
FP GFL+ +A+YQ EG W GK +IWD H +P D+ +
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 244 TGDIANDSYKLYKRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDEL 423
TGD+A+DSY RD E +RELGV +YRFS+SW R+LP N G+ YY L++ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 424 LKYNIEPMLTIYHWDLPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEP 600
+ ++P++T+YHWDLPQ+LQD GGW N + D + DYA + F+ FG +VK WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 601 KEICFQGYAIGTLAPAYTMSGVADYLCGKNVLL 699
+ + GYA G LAP S YL N+LL
Sbjct: 241 YVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLL 273
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 190 bits (462), Expect = 6e-48
Identities = 88/208 (42%), Positives = 128/208 (61%), Gaps = 1/208 (0%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FPK F +G T + Q+EG+W DGK +IWD H + + + + S+ + ++DSY ++D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWD---HFIHTHLKNVSSTNGSSDSYIFLEKD 137
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ + +GV +Y+FS+SW R+ P N G+ YY+ L+D L+ NIEP++T+YHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 469 LPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAP 645
LP LQ+ GGW N IID + DYA FQ FGDRVK WITI+ P + + GY G AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 646 AYTMSGVADYLCGKNVLLAHAKAYHIYD 729
+ A Y G N++ AH+K +H Y+
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 106 bits (255), Expect = 8e-23
Identities = 57/156 (36%), Positives = 82/156 (52%), Gaps = 5/156 (3%)
Frame = +1
Query: 280 KRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY 459
K+ +EM+ + V +YRF++ W +LPT +N + YY ++ E LK I M+T+Y
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 460 -----HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGY 624
H LP+ L GW NP + + YA + FQ+ GD VK WITINEP
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNR------ 696
Query: 625 AIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDK 732
L+ Y SG Y N+L+AHA A+ +YD+
Sbjct: 697 ----LSDIYNRSGNDTYGAAHNLLVAHALAWRLYDR 728
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 190 bits (462), Expect = 6e-48
Identities = 88/208 (42%), Positives = 128/208 (61%), Gaps = 1/208 (0%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FPK F +G T + Q+EG+W DGK +IWD H + + + + S+ + ++DSY ++D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWD---HFIHTHLKNVSSTNGSSDSYIFLEKD 137
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ + +GV +Y+FS+SW R+ P N G+ YY+ L+D L+ NIEP++T+YHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 469 LPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAP 645
LP LQ+ GGW N IID + DYA FQ FGDRVK WITI+ P + + GY G AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 646 AYTMSGVADYLCGKNVLLAHAKAYHIYD 729
+ A Y G N++ AH+K +H Y+
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 106 bits (255), Expect = 8e-23
Identities = 57/156 (36%), Positives = 82/156 (52%), Gaps = 5/156 (3%)
Frame = +1
Query: 280 KRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY 459
K+ +EM+ + V +YRF++ W +LPT +N + YY ++ E LK I M+T+Y
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 460 -----HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGY 624
H LP+ L GW NP + + YA + FQ+ GD VK WITINEP
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNR------ 696
Query: 625 AIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDK 732
L+ Y SG Y N+L+AHA A+ +YD+
Sbjct: 697 ----LSDIYNRSGNDTYGAAHNLLVAHALAWRLYDR 728
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 190 bits (462), Expect = 6e-48
Identities = 88/208 (42%), Positives = 128/208 (61%), Gaps = 1/208 (0%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FPK F +G T + Q+EG+W DGK +IWD H + + + + S+ + ++DSY ++D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWD---HFIHTHLKNVSSTNGSSDSYIFLEKD 137
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIYHWD 468
+ + +GV +Y+FS+SW R+ P N G+ YY+ L+D L+ NIEP++T+YHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 469 LPQKLQD-MGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIGTLAP 645
LP LQ+ GGW N IID + DYA FQ FGDRVK WITI+ P + + GY G AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 646 AYTMSGVADYLCGKNVLLAHAKAYHIYD 729
+ A Y G N++ AH+K +H Y+
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 106 bits (255), Expect = 8e-23
Identities = 57/156 (36%), Positives = 82/156 (52%), Gaps = 5/156 (3%)
Frame = +1
Query: 280 KRDVEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY 459
K+ +EM+ + V +YRF++ W +LPT +N + YY ++ E LK I M+T+Y
Sbjct: 583 KKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVTLY 642
Query: 460 -----HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGY 624
H LP+ L GW NP + + YA + FQ+ GD VK WITINEP
Sbjct: 643 YPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNR------ 696
Query: 625 AIGTLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDK 732
L+ Y SG Y N+L+AHA A+ +YD+
Sbjct: 697 ----LSDIYNRSGNDTYGAAHNLLVAHALAWRLYDR 728
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 102 bits (245), Expect = 1e-21
Identities = 43/95 (45%), Positives = 64/95 (67%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGV 393
++ I++LG+ +YRFS+SW+R+LP +IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 102 bits (245), Expect = 1e-21
Identities = 43/95 (45%), Positives = 64/95 (67%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGV 393
++ I++LG+ +YRFS+SW+R+LP +IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 101 bits (243), Expect = 2e-21
Identities = 43/95 (45%), Positives = 64/95 (67%)
Frame = +1
Query: 109 FPKGFLFGAATASYQIEGAWNIDGKTENIWDRACHKVPSPVADNSTGDIANDSYKLYKRD 288
FP GF + AATA+YQ+EG W+ DGK +WD H+ V N TGD+A SY L++ D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGV 393
++ I++LG+ +YRFS+SW+R+LP +IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 93.9 bits (223), Expect = 6e-19
Identities = 52/153 (33%), Positives = 82/153 (53%), Gaps = 5/153 (3%)
Frame = +1
Query: 289 VEMIRELGVDYYRFSVSWTRILPTSFPDYINEAGVAYYNNLIDELLKYNIEPMLTIY--- 459
+ +++E+ V ++RFS+ W ILP +N + YY + EL++ NI P++ ++
Sbjct: 309 IALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVALWQPM 368
Query: 460 --HWDLPQKLQDMGGWTNPYIIDWYADYARVLFQKFGDRVKNWITINEPKEICFQGYAIG 633
+ LP+ L G W NPY +A+YAR+ FQ+ G VK WIT+NEP
Sbjct: 369 APNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP----------- 417
Query: 634 TLAPAYTMSGVADYLCGKNVLLAHAKAYHIYDK 732
YT + Y G N+L AHA A+H+Y++
Sbjct: 418 -----YTRN--MTYSAGHNLLKAHALAWHVYNE 443
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,118,775
Number of Sequences: 237096
Number of extensions: 2423236
Number of successful extensions: 4804
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 4254
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4763
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9534535578
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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