Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV18p04f
(761 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
EF426482-1|ABR08387.1| 399|Homo sapiens lipase K protein. 181 3e-45
AL358532-3|CAH71058.2| 399|Homo sapiens lipase, family member K... 181 3e-45
BC113711-1|AAI13712.1| 398|Homo sapiens lipase, gastric protein. 180 4e-45
BC112272-1|AAI12273.1| 398|Homo sapiens lipase, gastric protein. 180 4e-45
AK223468-1|BAD97188.1| 398|Homo sapiens lipase, gastric variant... 180 4e-45
X05997-2|CAA29414.1| 392|Homo sapiens gastric lipase precursor ... 179 1e-44
X05997-1|CAA29413.1| 398|Homo sapiens gastric lipase precursor ... 179 1e-44
AY631869-1|AAT38115.1| 398|Homo sapiens lipase, gastric protein. 179 1e-44
AL358532-1|CAH71057.1| 398|Homo sapiens lipase, gastric protein. 179 1e-44
Z31690-1|CAA83495.1| 399|Homo sapiens lysosomal acid lipase pro... 166 7e-41
U08464-1|AAB60328.1| 399|Homo sapiens lysosomal acid lipase pro... 166 7e-41
X76488-1|CAA54026.1| 399|Homo sapiens sterol esterase protein. 163 5e-40
U04285-1|AAB60327.1| 399|Homo sapiens lysosomal acid lipase/cho... 163 5e-40
AL513533-3|CAI13517.1| 290|Homo sapiens lipase A, lysosomal aci... 163 5e-40
AL513533-2|CAI13516.1| 399|Homo sapiens lipase A, lysosomal aci... 163 5e-40
AL353751-4|CAI12237.1| 290|Homo sapiens lipase A, lysosomal aci... 163 5e-40
AL353751-3|CAI12236.1| 399|Homo sapiens lipase A, lysosomal aci... 163 5e-40
AL353751-2|CAI12235.1| 219|Homo sapiens lipase A, lysosomal aci... 163 5e-40
AK222760-1|BAD96480.1| 399|Homo sapiens lipase A precursor vari... 163 5e-40
M74775-1|AAA59519.1| 399|Homo sapiens lysosomal acid lipase/cho... 163 6e-40
BC012287-1|AAH12287.1| 399|Homo sapiens lipase A, lysosomal aci... 162 1e-39
EF426484-1|ABR08389.1| 423|Homo sapiens lipase M protein. 161 2e-39
AL358532-7|CAO77925.1| 423|Homo sapiens lipase, family member M... 161 2e-39
AL353113-2|CAH72238.2| 423|Homo sapiens lipase, family member M... 161 2e-39
BC031219-1|AAH31219.1| 366|Homo sapiens lipase, family member J... 156 9e-38
AL139406-3|CAH73713.1| 366|Homo sapiens lipase, family member J... 156 9e-38
EF426483-1|ABR08388.1| 398|Homo sapiens lipase N protein. 144 2e-34
AL358532-5|CAH71060.2| 398|Homo sapiens lipase, family member N... 144 2e-34
AL358532-2|CAH71056.1| 365|Homo sapiens lipase, gastric protein. 105 9e-32
AL513533-1|CAI13515.1| 343|Homo sapiens lipase A, lysosomal aci... 124 3e-28
AL353751-1|CAI12234.1| 343|Homo sapiens lipase A, lysosomal aci... 124 3e-28
AL353146-2|CAI12380.1| 343|Homo sapiens lipase A, lysosomal aci... 124 3e-28
AK125193-1|BAC86078.1| 401|Homo sapiens . protein. 114 4e-25
AY781819-1|AAW29122.1| 128|Homo sapiens AF2 non-allergic IgE he... 32 1.9
AY032602-1|AAK52083.1| 410|Homo sapiens CLIC5B protein. 31 4.5
AL357057-2|CAI16805.1| 410|Homo sapiens chloride intracellular ... 31 4.5
AL050336-3|CAI21031.1| 410|Homo sapiens chloride intracellular ... 31 4.5
AF062236-1|AAC18272.1| 118|Homo sapiens immunoglobulin heavy ch... 31 4.5
AF103331-1|AAD20500.1| 117|Homo sapiens immunoglobulin heavy ch... 31 5.9
AM081913-1|CAL06059.1| 102|Homo sapiens immunoglobulin heavy ch... 30 7.8
>EF426482-1|ABR08387.1| 399|Homo sapiens lipase K protein.
Length = 399
Score = 181 bits (440), Expect = 3e-45
Identities = 90/204 (44%), Positives = 130/204 (63%)
Frame = +2
Query: 101 LYRLDAQGSRYSTNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNN 280
+Y D +G+ N +A ++I +I+ +GYP E + V T+DGYIL + RIPHGR
Sbjct: 17 MYGYDKKGN----NANPEANMNISQIISYWGYPYEEYDVTTKDGYILGIYRIPHGRGCPG 72
Query: 281 RPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLD 460
R P KPAV + HGL ASA++W+ P LA++LA++GYDVWLGN+RG +SR H KL
Sbjct: 73 RTAP-KPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLKLS 131
Query: 461 PDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNS 640
P E+W FS +E+ DLPA I++ ++ G++RL+Y+GHSQGTT+ + S PE
Sbjct: 132 P-KSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFIAFSTNPELAK 190
Query: 641 KIIAMQAYAPVAYLEFNANRLLKL 712
KI A APV +++ + + KL
Sbjct: 191 KIKIFFALAPVVTVKYTQSPMKKL 214
>AL358532-3|CAH71058.2| 399|Homo sapiens lipase, family member K
protein.
Length = 399
Score = 181 bits (440), Expect = 3e-45
Identities = 90/204 (44%), Positives = 130/204 (63%)
Frame = +2
Query: 101 LYRLDAQGSRYSTNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNN 280
+Y D +G+ N +A ++I +I+ +GYP E + V T+DGYIL + RIPHGR
Sbjct: 17 MYGYDKKGN----NANPEANMNISQIISYWGYPYEEYDVTTKDGYILGIYRIPHGRGCPG 72
Query: 281 RPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLD 460
R P KPAV + HGL ASA++W+ P LA++LA++GYDVWLGN+RG +SR H KL
Sbjct: 73 RTAP-KPAVYLQHGLIASASNWICNLPNNSLAFLLADSGYDVWLGNSRGNTWSRKHLKLS 131
Query: 461 PDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNS 640
P E+W FS +E+ DLPA I++ ++ G++RL+Y+GHSQGTT+ + S PE
Sbjct: 132 P-KSPEYWAFSLDEMAKYDLPATINFIIEKTGQKRLYYVGHSQGTTIAFIAFSTNPELAK 190
Query: 641 KIIAMQAYAPVAYLEFNANRLLKL 712
KI A APV +++ + + KL
Sbjct: 191 KIKIFFALAPVVTVKYTQSPMKKL 214
>BC113711-1|AAI13712.1| 398|Homo sapiens lipase, gastric protein.
Length = 398
Score = 180 bits (439), Expect = 4e-45
Identities = 86/187 (45%), Positives = 127/187 (67%)
Frame = +2
Query: 152 DALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFA 331
+ ++I +IT +GYP E ++VVTEDGYILE+ RIP+G+ +N+ ++P V + HGL A
Sbjct: 30 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGK-KNSGNTGQRPVVFLQHGLLA 88
Query: 332 SAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEEIGT 511
SA +W+ P LA+ILA+AGYDVWLGN+RG ++R + PD+ EFW FS++E+
Sbjct: 89 SATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDS-VEFWAFSFDEMAK 147
Query: 512 RDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFN 691
DLPA ID+ +K AG+++LHY+GHSQGTT+ + S P +I A APVA +++
Sbjct: 148 YDLPATIDFIVKKAGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYT 207
Query: 692 ANRLLKL 712
+ + KL
Sbjct: 208 KSLINKL 214
>BC112272-1|AAI12273.1| 398|Homo sapiens lipase, gastric protein.
Length = 398
Score = 180 bits (439), Expect = 4e-45
Identities = 86/187 (45%), Positives = 127/187 (67%)
Frame = +2
Query: 152 DALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFA 331
+ ++I +IT +GYP E ++VVTEDGYILE+ RIP+G+ +N+ ++P V + HGL A
Sbjct: 30 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGK-KNSGNTGQRPVVFLQHGLLA 88
Query: 332 SAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEEIGT 511
SA +W+ P LA+ILA+AGYDVWLGN+RG ++R + PD+ EFW FS++E+
Sbjct: 89 SATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDS-VEFWAFSFDEMAK 147
Query: 512 RDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFN 691
DLPA ID+ +K AG+++LHY+GHSQGTT+ + S P +I A APVA +++
Sbjct: 148 YDLPATIDFIVKKAGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYT 207
Query: 692 ANRLLKL 712
+ + KL
Sbjct: 208 KSLINKL 214
>AK223468-1|BAD97188.1| 398|Homo sapiens lipase, gastric variant
protein.
Length = 398
Score = 180 bits (439), Expect = 4e-45
Identities = 86/187 (45%), Positives = 127/187 (67%)
Frame = +2
Query: 152 DALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFA 331
+ ++I +IT +GYP E ++VVTEDGYILE+ RIP+G+ +N+ ++P V + HGL A
Sbjct: 30 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGK-KNSGNTGQRPVVFLQHGLLA 88
Query: 332 SAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEEIGT 511
SA +W+ P LA+ILA+AGYDVWLGN+RG ++R + PD+ EFW FS++E+
Sbjct: 89 SATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDS-VEFWAFSFDEMAK 147
Query: 512 RDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFN 691
DLPA ID+ +K AG+++LHY+GHSQGTT+ + S P +I A APVA +++
Sbjct: 148 YDLPATIDFIVKKAGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYT 207
Query: 692 ANRLLKL 712
+ + KL
Sbjct: 208 KSLINKL 214
>X05997-2|CAA29414.1| 392|Homo sapiens gastric lipase precursor
protein.
Length = 392
Score = 179 bits (435), Expect = 1e-44
Identities = 85/187 (45%), Positives = 126/187 (67%)
Frame = +2
Query: 152 DALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFA 331
+ ++I +IT +GYP E ++VVTEDGYILE+ RIP+G+ +N+ ++P V + HGL A
Sbjct: 24 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGK-KNSGNTGQRPVVFLQHGLLA 82
Query: 332 SAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEEIGT 511
SA +W+ P LA+ILA+AGYDVWLGN+RG ++R + PD+ EFW FS++E+
Sbjct: 83 SATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDS-VEFWAFSFDEMAK 141
Query: 512 RDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFN 691
DLPA ID+ +K G+++LHY+GHSQGTT+ + S P +I A APVA +++
Sbjct: 142 YDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYT 201
Query: 692 ANRLLKL 712
+ + KL
Sbjct: 202 KSLINKL 208
>X05997-1|CAA29413.1| 398|Homo sapiens gastric lipase precursor
protein.
Length = 398
Score = 179 bits (435), Expect = 1e-44
Identities = 85/187 (45%), Positives = 126/187 (67%)
Frame = +2
Query: 152 DALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFA 331
+ ++I +IT +GYP E ++VVTEDGYILE+ RIP+G+ +N+ ++P V + HGL A
Sbjct: 30 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGK-KNSGNTGQRPVVFLQHGLLA 88
Query: 332 SAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEEIGT 511
SA +W+ P LA+ILA+AGYDVWLGN+RG ++R + PD+ EFW FS++E+
Sbjct: 89 SATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDS-VEFWAFSFDEMAK 147
Query: 512 RDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFN 691
DLPA ID+ +K G+++LHY+GHSQGTT+ + S P +I A APVA +++
Sbjct: 148 YDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYT 207
Query: 692 ANRLLKL 712
+ + KL
Sbjct: 208 KSLINKL 214
>AY631869-1|AAT38115.1| 398|Homo sapiens lipase, gastric protein.
Length = 398
Score = 179 bits (435), Expect = 1e-44
Identities = 85/187 (45%), Positives = 126/187 (67%)
Frame = +2
Query: 152 DALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFA 331
+ ++I +IT +GYP E ++VVTEDGYILE+ RIP+G+ +N+ ++P V + HGL A
Sbjct: 30 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGK-KNSGNTGQRPVVFLQHGLLA 88
Query: 332 SAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEEIGT 511
SA +W+ P LA+ILA+AGYDVWLGN+RG ++R + PD+ EFW FS++E+
Sbjct: 89 SATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDS-VEFWAFSFDEMAK 147
Query: 512 RDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFN 691
DLPA ID+ +K G+++LHY+GHSQGTT+ + S P +I A APVA +++
Sbjct: 148 YDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYT 207
Query: 692 ANRLLKL 712
+ + KL
Sbjct: 208 KSLINKL 214
>AL358532-1|CAH71057.1| 398|Homo sapiens lipase, gastric protein.
Length = 398
Score = 179 bits (435), Expect = 1e-44
Identities = 85/187 (45%), Positives = 126/187 (67%)
Frame = +2
Query: 152 DALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFA 331
+ ++I +IT +GYP E ++VVTEDGYILE+ RIP+G+ +N+ ++P V + HGL A
Sbjct: 30 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGK-KNSGNTGQRPVVFLQHGLLA 88
Query: 332 SAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEEIGT 511
SA +W+ P LA+ILA+AGYDVWLGN+RG ++R + PD+ EFW FS++E+
Sbjct: 89 SATNWISNLPNNSLAFILADAGYDVWLGNSRGNTWARRNLYYSPDS-VEFWAFSFDEMAK 147
Query: 512 RDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFN 691
DLPA ID+ +K G+++LHY+GHSQGTT+ + S P +I A APVA +++
Sbjct: 148 YDLPATIDFIVKKTGQKQLHYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYT 207
Query: 692 ANRLLKL 712
+ + KL
Sbjct: 208 KSLINKL 214
>Z31690-1|CAA83495.1| 399|Homo sapiens lysosomal acid lipase
protein.
Length = 399
Score = 166 bits (404), Expect = 7e-41
Identities = 85/205 (41%), Positives = 126/205 (61%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GSR T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWTLHSEGSRGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>U08464-1|AAB60328.1| 399|Homo sapiens lysosomal acid lipase
protein.
Length = 399
Score = 166 bits (404), Expect = 7e-41
Identities = 85/205 (41%), Positives = 126/205 (61%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GSR T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWTLHSEGSRGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>X76488-1|CAA54026.1| 399|Homo sapiens sterol esterase protein.
Length = 399
Score = 163 bits (397), Expect = 5e-40
Identities = 84/205 (40%), Positives = 125/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GS T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>U04285-1|AAB60327.1| 399|Homo sapiens lysosomal acid
lipase/cholesteryl ester hydrolase protein.
Length = 399
Score = 163 bits (397), Expect = 5e-40
Identities = 84/205 (40%), Positives = 125/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GS T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>AL513533-3|CAI13517.1| 290|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 290
Score = 163 bits (397), Expect = 5e-40
Identities = 84/205 (40%), Positives = 125/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GS T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>AL513533-2|CAI13516.1| 399|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 399
Score = 163 bits (397), Expect = 5e-40
Identities = 84/205 (40%), Positives = 125/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GS T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>AL353751-4|CAI12237.1| 290|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 290
Score = 163 bits (397), Expect = 5e-40
Identities = 84/205 (40%), Positives = 125/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GS T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>AL353751-3|CAI12236.1| 399|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 399
Score = 163 bits (397), Expect = 5e-40
Identities = 84/205 (40%), Positives = 125/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GS T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>AL353751-2|CAI12235.1| 219|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 219
Score = 163 bits (397), Expect = 5e-40
Identities = 84/205 (40%), Positives = 125/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GS T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>AK222760-1|BAD96480.1| 399|Homo sapiens lipase A precursor variant
protein.
Length = 399
Score = 163 bits (397), Expect = 5e-40
Identities = 84/205 (40%), Positives = 125/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GS T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWTLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>M74775-1|AAA59519.1| 399|Homo sapiens lysosomal acid
lipase/cholesteryl esterase protein.
Length = 399
Score = 163 bits (396), Expect = 6e-40
Identities = 84/205 (40%), Positives = 125/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GS T V + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWPLHSEGSGGKLTAVDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>BC012287-1|AAH12287.1| 399|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 399
Score = 162 bits (393), Expect = 1e-39
Identities = 83/205 (40%), Positives = 125/205 (60%), Gaps = 1/205 (0%)
Frame = +2
Query: 101 LYRLDAQGSRYS-TNVTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQN 277
L+ L ++GS T + + +++ +I+ +G+P E + V TEDGYIL + RIPHGR +
Sbjct: 14 LWPLHSEGSGGKLTALDPETNMNVSEIISYWGFPSEEYLVETEDGYILCLNRIPHGRKNH 73
Query: 278 NRPDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKL 457
+ P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 74 SDKGP-KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTL 132
Query: 458 DPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYN 637
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 SVSQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELA 191
Query: 638 SKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 192 KRIKMFFALGPVASVAFCTSPMAKL 216
>EF426484-1|ABR08389.1| 423|Homo sapiens lipase M protein.
Length = 423
Score = 161 bits (392), Expect = 2e-39
Identities = 79/178 (44%), Positives = 113/178 (63%)
Frame = +2
Query: 143 VTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHG 322
V +A ++I +I GYP E ++V TEDGYIL + RIP G Q + R P VL+ HG
Sbjct: 41 VDPEAFMNISEIIQHQGYPCEEYEVATEDGYILSVNRIPRGLVQPKKTGSR-PVVLLQHG 99
Query: 323 LFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEE 502
L A++W+ P L +ILA+AG+DVW+GN+RG +SR H L D D EFW FS++E
Sbjct: 100 LVGGASNWISNLPNNSLGFILADAGFDVWMGNSRGNAWSRKHKTLSIDQD-EFWAFSYDE 158
Query: 503 IGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVA 676
+ DLPA+I++ L+ G+ +++Y+G+SQGTT+ + S PE KI A AP+A
Sbjct: 159 MARFDLPAVINFILQKTGQEKIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIA 216
>AL358532-7|CAO77925.1| 423|Homo sapiens lipase, family member M
protein.
Length = 423
Score = 161 bits (392), Expect = 2e-39
Identities = 79/178 (44%), Positives = 113/178 (63%)
Frame = +2
Query: 143 VTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHG 322
V +A ++I +I GYP E ++V TEDGYIL + RIP G Q + R P VL+ HG
Sbjct: 41 VDPEAFMNISEIIQHQGYPCEEYEVATEDGYILSVNRIPRGLVQPKKTGSR-PVVLLQHG 99
Query: 323 LFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEE 502
L A++W+ P L +ILA+AG+DVW+GN+RG +SR H L D D EFW FS++E
Sbjct: 100 LVGGASNWISNLPNNSLGFILADAGFDVWMGNSRGNAWSRKHKTLSIDQD-EFWAFSYDE 158
Query: 503 IGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVA 676
+ DLPA+I++ L+ G+ +++Y+G+SQGTT+ + S PE KI A AP+A
Sbjct: 159 MARFDLPAVINFILQKTGQEKIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIA 216
>AL353113-2|CAH72238.2| 423|Homo sapiens lipase, family member M
protein.
Length = 423
Score = 161 bits (392), Expect = 2e-39
Identities = 79/178 (44%), Positives = 113/178 (63%)
Frame = +2
Query: 143 VTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHG 322
V +A ++I +I GYP E ++V TEDGYIL + RIP G Q + R P VL+ HG
Sbjct: 41 VDPEAFMNISEIIQHQGYPCEEYEVATEDGYILSVNRIPRGLVQPKKTGSR-PVVLLQHG 99
Query: 323 LFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEE 502
L A++W+ P L +ILA+AG+DVW+GN+RG +SR H L D D EFW FS++E
Sbjct: 100 LVGGASNWISNLPNNSLGFILADAGFDVWMGNSRGNAWSRKHKTLSIDQD-EFWAFSYDE 158
Query: 503 IGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVA 676
+ DLPA+I++ L+ G+ +++Y+G+SQGTT+ + S PE KI A AP+A
Sbjct: 159 MARFDLPAVINFILQKTGQEKIYYVGYSQGTTMGFIAFSTMPELAQKIKMYFALAPIA 216
>BC031219-1|AAH31219.1| 366|Homo sapiens lipase, family member J
protein.
Length = 366
Score = 156 bits (378), Expect = 9e-38
Identities = 75/184 (40%), Positives = 115/184 (62%)
Frame = +2
Query: 161 LDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFASAA 340
++I +I+ +GYP E + +VTEDGYIL + RIP+ R NN+ ++ V + HGL SA+
Sbjct: 1 MNISQIISYWGYPDEEYDIVTEDGYILGLYRIPYWRTDNNKNLAQRVVVYLQHGLLTSAS 60
Query: 341 DWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEEIGTRDL 520
W+ P L +ILA+AGYDVW+GN+RG +SR H L+ + EFW FS++E+ DL
Sbjct: 61 SWISNLPNNSLGFILADAGYDVWMGNSRGNTWSRKHLYLE-TSSKEFWAFSFDEMAKYDL 119
Query: 521 PAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANR 700
PA ID+T+K + + Y+GHSQGTT+ + S + +I A APV ++ +
Sbjct: 120 PASIDFTVKQTRQEEIFYVGHSQGTTIGFITFSTISKIAERIKIFFALAPVFSTKYLKSP 179
Query: 701 LLKL 712
L+++
Sbjct: 180 LIRM 183
>AL139406-3|CAH73713.1| 366|Homo sapiens lipase, family member J
protein.
Length = 366
Score = 156 bits (378), Expect = 9e-38
Identities = 75/184 (40%), Positives = 115/184 (62%)
Frame = +2
Query: 161 LDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFASAA 340
++I +I+ +GYP E + +VTEDGYIL + RIP+ R NN+ ++ V + HGL SA+
Sbjct: 1 MNISQIISYWGYPDEEYDIVTEDGYILGLYRIPYWRTDNNKNLAQRVVVYLQHGLLTSAS 60
Query: 341 DWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEEIGTRDL 520
W+ P L +ILA+AGYDVW+GN+RG +SR H L+ + EFW FS++E+ DL
Sbjct: 61 SWISNLPNNSLGFILADAGYDVWMGNSRGNTWSRKHLYLE-TSSKEFWAFSFDEMAKYDL 119
Query: 521 PAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANR 700
PA ID+T+K + + Y+GHSQGTT+ + S + +I A APV ++ +
Sbjct: 120 PASIDFTVKQTRQEEIFYVGHSQGTTIGFITFSTISKIAERIKIFFALAPVFSTKYLKSP 179
Query: 701 LLKL 712
L+++
Sbjct: 180 LIRM 183
>EF426483-1|ABR08388.1| 398|Homo sapiens lipase N protein.
Length = 398
Score = 144 bits (350), Expect = 2e-34
Identities = 72/182 (39%), Positives = 105/182 (57%)
Frame = +2
Query: 143 VTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHG 322
V + ++ +I GYP E ++V TEDGYIL + RIP+GR PR P V + H
Sbjct: 28 VNPEVWMNTSEIIIYNGYPSEEYEVTTEDGYILLVNRIPYGRTHARSTGPR-PVVYMQHA 86
Query: 323 LFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEE 502
LFA A W+ L ++LA+AGYDVW+GN+RG +SR H L + D +FW FS++E
Sbjct: 87 LFADNAYWLENYANGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLS-ETDEKFWAFSFDE 145
Query: 503 IGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYL 682
+ DLP +ID+ + G+ +L++IGHS GTT+ + S PE +I A P
Sbjct: 146 MAKYDLPGVIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPTISF 205
Query: 683 EF 688
++
Sbjct: 206 KY 207
>AL358532-5|CAH71060.2| 398|Homo sapiens lipase, family member N
protein.
Length = 398
Score = 144 bits (350), Expect = 2e-34
Identities = 72/182 (39%), Positives = 105/182 (57%)
Frame = +2
Query: 143 VTEDALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPDPRKPAVLVMHG 322
V + ++ +I GYP E ++V TEDGYIL + RIP+GR PR P V + H
Sbjct: 28 VNPEVWMNTSEIIIYNGYPSEEYEVTTEDGYILLVNRIPYGRTHARSTGPR-PVVYMQHA 86
Query: 323 LFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEE 502
LFA A W+ L ++LA+AGYDVW+GN+RG +SR H L + D +FW FS++E
Sbjct: 87 LFADNAYWLENYANGSLGFLLADAGYDVWMGNSRGNTWSRRHKTLS-ETDEKFWAFSFDE 145
Query: 503 IGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYL 682
+ DLP +ID+ + G+ +L++IGHS GTT+ + S PE +I A P
Sbjct: 146 MAKYDLPGVIDFIVNKTGQEKLYFIGHSLGTTIGFVAFSTMPELAQRIKMNFALGPTISF 205
Query: 683 EF 688
++
Sbjct: 206 KY 207
>AL358532-2|CAH71056.1| 365|Homo sapiens lipase, gastric protein.
Length = 365
Score = 105 bits (251), Expect(2) = 9e-32
Identities = 48/108 (44%), Positives = 71/108 (65%)
Frame = +2
Query: 389 EAGYDVWLGNARGTYYSRAHTKLDPDNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRL 568
+AGYDVWLGN+RG ++R + PD+ EFW FS++E+ DLPA ID+ +K G+++L
Sbjct: 75 DAGYDVWLGNSRGNTWARRNLYYSPDS-VEFWAFSFDEMAKYDLPATIDFIVKKTGQKQL 133
Query: 569 HYIGHSQGTTVFWAMGSLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL 712
HY+GHSQGTT+ + S P +I A APVA +++ + + KL
Sbjct: 134 HYVGHSQGTTIGFIAFSTNPSLAKRIKTFYALAPVATVKYTKSLINKL 181
Score = 52.4 bits (120), Expect(2) = 9e-32
Identities = 22/46 (47%), Positives = 33/46 (71%)
Frame = +2
Query: 152 DALLDIVGLITKYGYPVEVHKVVTEDGYILEMQRIPHGRDQNNRPD 289
+ ++I +IT +GYP E ++VVTEDGYILE+ RIP+G+ + D
Sbjct: 30 EVTMNISQMITYWGYPNEEYEVVTEDGYILEVNRIPYGKKNSGNTD 75
>AL513533-1|CAI13515.1| 343|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 343
Score = 124 bits (300), Expect = 3e-28
Identities = 60/143 (41%), Positives = 86/143 (60%)
Frame = +2
Query: 284 PDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDP 463
P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 19 PSGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSV 78
Query: 464 DNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSK 643
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE +
Sbjct: 79 SQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKR 137
Query: 644 IIAMQAYAPVAYLEFNANRLLKL 712
I A PVA + F + + KL
Sbjct: 138 IKMFFALGPVASVAFCTSPMAKL 160
>AL353751-1|CAI12234.1| 343|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 343
Score = 124 bits (300), Expect = 3e-28
Identities = 60/143 (41%), Positives = 86/143 (60%)
Frame = +2
Query: 284 PDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDP 463
P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 19 PSGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSV 78
Query: 464 DNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSK 643
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE +
Sbjct: 79 SQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKR 137
Query: 644 IIAMQAYAPVAYLEFNANRLLKL 712
I A PVA + F + + KL
Sbjct: 138 IKMFFALGPVASVAFCTSPMAKL 160
>AL353146-2|CAI12380.1| 343|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 343
Score = 124 bits (300), Expect = 3e-28
Identities = 60/143 (41%), Positives = 86/143 (60%)
Frame = +2
Query: 284 PDPRKPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDP 463
P KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L
Sbjct: 19 PSGPKPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSV 78
Query: 464 DNDSEFWKFSWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEYNSK 643
D EFW FS++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE +
Sbjct: 79 SQD-EFWAFSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPELAKR 137
Query: 644 IIAMQAYAPVAYLEFNANRLLKL 712
I A PVA + F + + KL
Sbjct: 138 IKMFFALGPVASVAFCTSPMAKL 160
>AK125193-1|BAC86078.1| 401|Homo sapiens . protein.
Length = 401
Score = 114 bits (274), Expect = 4e-25
Identities = 59/146 (40%), Positives = 85/146 (58%), Gaps = 7/146 (4%)
Frame = +2
Query: 296 KPAVLVMHGLFASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYSRAHTKLDPDNDS 475
KP V + HGL A +++WV L +ILA+AG+DVW+GN+RG +SR H L D
Sbjct: 74 KPVVFLQHGLLADSSNWVTNLANSSLGFILADAGFDVWMGNSRGNTWSRKHKTLSVSQD- 132
Query: 476 EFWKF-------SWEEIGTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSLRPEY 634
EFW F S++E+ DLPA I++ L G+ +++Y+GHSQGTT+ + S PE
Sbjct: 133 EFWAFRVPFLDYSYDEMAKYDLPASINFILNKTGQEQVYYVGHSQGTTIGFIAFSQIPEL 192
Query: 635 NSKIIAMQAYAPVAYLEFNANRLLKL 712
+I A PVA + F + + KL
Sbjct: 193 AKRIKMFFALGPVASVAFCTSPMAKL 218
>AY781819-1|AAW29122.1| 128|Homo sapiens AF2 non-allergic IgE heavy
chain IGHV3-23 protein.
Length = 128
Score = 32.3 bits (70), Expect = 1.9
Identities = 20/64 (31%), Positives = 28/64 (43%), Gaps = 3/64 (4%)
Frame = +2
Query: 335 AADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYS---RAHTKLDPDNDSEFWKFSWEEI 505
A DWV PG GL ++ AG+ +GN GTYY+ + + DN +
Sbjct: 32 AMDWVRPAPGKGLEWV---AGF---IGNGAGTYYADSVKGRFTISRDNSQNMLDLQMNSL 85
Query: 506 GTRD 517
T D
Sbjct: 86 RTED 89
>AY032602-1|AAK52083.1| 410|Homo sapiens CLIC5B protein.
Length = 410
Score = 31.1 bits (67), Expect = 4.5
Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 1/97 (1%)
Frame = +2
Query: 56 QATVRRSPHADYVEELYRLDAQGSRYSTNVTEDALLDIVGLITKYGYPVEVHKVVTED-G 232
Q SPH D V E R + Y+T + D V + T G + V +ED G
Sbjct: 24 QPEENESPHYDDVHEYLR--PENDLYATQLNTHEY-DFVSVYTIKGEETSLASVQSEDRG 80
Query: 233 YILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFASAAD 343
Y+L I + + +P++ + M GL++S D
Sbjct: 81 YLLP-DEIYSELQEAHPGEPQEDRGISMEGLYSSTQD 116
>AL357057-2|CAI16805.1| 410|Homo sapiens chloride intracellular
channel 5 protein.
Length = 410
Score = 31.1 bits (67), Expect = 4.5
Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 1/97 (1%)
Frame = +2
Query: 56 QATVRRSPHADYVEELYRLDAQGSRYSTNVTEDALLDIVGLITKYGYPVEVHKVVTED-G 232
Q SPH D V E R + Y+T + D V + T G + V +ED G
Sbjct: 24 QPEENESPHYDDVHEYLR--PENDLYATQLNTHEY-DFVSVYTIKGEETSLASVQSEDRG 80
Query: 233 YILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFASAAD 343
Y+L I + + +P++ + M GL++S D
Sbjct: 81 YLLP-DEIYSELQEAHPGEPQEDRGISMEGLYSSTQD 116
>AL050336-3|CAI21031.1| 410|Homo sapiens chloride intracellular
channel 5 protein.
Length = 410
Score = 31.1 bits (67), Expect = 4.5
Identities = 27/97 (27%), Positives = 42/97 (43%), Gaps = 1/97 (1%)
Frame = +2
Query: 56 QATVRRSPHADYVEELYRLDAQGSRYSTNVTEDALLDIVGLITKYGYPVEVHKVVTED-G 232
Q SPH D V E R + Y+T + D V + T G + V +ED G
Sbjct: 24 QPEENESPHYDDVHEYLR--PENDLYATQLNTHEY-DFVSVYTIKGEETSLASVQSEDRG 80
Query: 233 YILEMQRIPHGRDQNNRPDPRKPAVLVMHGLFASAAD 343
Y+L I + + +P++ + M GL++S D
Sbjct: 81 YLLP-DEIYSELQEAHPGEPQEDRGISMEGLYSSTQD 116
>AF062236-1|AAC18272.1| 118|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 118
Score = 31.1 bits (67), Expect = 4.5
Identities = 26/99 (26%), Positives = 37/99 (37%), Gaps = 3/99 (3%)
Frame = +2
Query: 335 AADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYS---RAHTKLDPDNDSEFWKFSWEEI 505
A WV PG GL Y+ A + N TYY+ + + DN +
Sbjct: 24 AMHWVRQAPGKGLEYVSAIS------SNGGSTYYADSVKGRFTISRDNSKNTLYLQMSSL 77
Query: 506 GTRDLPAMIDYTLKVAGKRRLHYIGHSQGTTVFWAMGSL 622
D + Y +K A +L Y S T +W G+L
Sbjct: 78 RAED--TAVYYCVKDA--TQLRYFDWSSSTLDYWGQGTL 112
>AF103331-1|AAD20500.1| 117|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 117
Score = 30.7 bits (66), Expect = 5.9
Identities = 19/66 (28%), Positives = 29/66 (43%), Gaps = 3/66 (4%)
Frame = +2
Query: 329 ASAADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYS---RAHTKLDPDNDSEFWKFSWE 499
+SA +WV PG GL ++ A + G+ TYY+ R + DND +
Sbjct: 24 SSAMNWVRQSPGKGLEWVAAIS------GSGGSTYYANSVRGRFTISRDNDKDTVHLQMN 77
Query: 500 EIGTRD 517
+G D
Sbjct: 78 SLGAED 83
>AM081913-1|CAL06059.1| 102|Homo sapiens immunoglobulin heavy chain
variable region protein.
Length = 102
Score = 30.3 bits (65), Expect = 7.8
Identities = 15/35 (42%), Positives = 19/35 (54%)
Frame = +2
Query: 335 AADWVLMGPGLGLAYILAEAGYDVWLGNARGTYYS 439
A WV PG GL ++ A +G G RGTYY+
Sbjct: 36 AMSWVRQAPGKGLEWVSAISG-----GGGRGTYYA 65
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 117,691,701
Number of Sequences: 237096
Number of extensions: 2677098
Number of successful extensions: 12378
Number of sequences better than 10.0: 40
Number of HSP's better than 10.0 without gapping: 12042
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 12319
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9144232952
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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