Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV18k23r
(798 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 178 2e-44
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 178 2e-44
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 178 2e-44
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 178 2e-44
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 177 4e-44
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 175 2e-43
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 173 8e-43
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 172 1e-42
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 172 1e-42
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 145 2e-34
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 144 2e-34
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 90 7e-18
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 90 7e-18
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 90 7e-18
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 77 7e-14
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 77 7e-14
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 77 7e-14
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 75 4e-13
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 75 4e-13
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 75 4e-13
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 75 4e-13
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 75 4e-13
BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein. 67 8e-11
CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein. 31 4.8
U83246-1|AAC15920.1| 537|Homo sapiens copine I protein. 31 6.4
BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein. 31 6.4
AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein. 31 6.4
AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein. 31 6.4
AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein. 31 6.4
AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein. 31 6.4
AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation ... 30 8.4
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 178 bits (434), Expect = 2e-44
Identities = 85/239 (35%), Positives = 140/239 (58%), Gaps = 1/239 (0%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
S D+ AA+ ++ PIF +G +P+ + +++A S + GYP +RLP+ +EEE+
Sbjct: 236 SVSDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEK 294
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
+I+GTADFF V +YT L+ ++ + + + D + + P W W+ ++P
Sbjct: 295 KMIKGTADFFAVQYYTTRLIKYQEN--KKGELGILQDAEIEFFPDPSWKN--VDWIYVVP 350
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VR 260
+ +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++ V
Sbjct: 351 WGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVN 410
Query: 259 LKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVIDHDL 83
L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++ L
Sbjct: 411 LQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 178 bits (434), Expect = 2e-44
Identities = 85/239 (35%), Positives = 140/239 (58%), Gaps = 1/239 (0%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
S D+ AA+ ++ PIF +G +P+ + +++A S + GYP +RLP+ +EEE+
Sbjct: 236 SVSDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEK 294
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
+I+GTADFF V +YT L+ ++ + + + D + + P W W+ ++P
Sbjct: 295 KMIKGTADFFAVQYYTTRLIKYQEN--KKGELGILQDAEIEFFPDPSWKN--VDWIYVVP 350
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VR 260
+ +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++ V
Sbjct: 351 WGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVN 410
Query: 259 LKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVIDHDL 83
L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++ L
Sbjct: 411 LQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 178 bits (434), Expect = 2e-44
Identities = 85/239 (35%), Positives = 140/239 (58%), Gaps = 1/239 (0%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
S D+ AA+ ++ PIF +G +P+ + +++A S + GYP +RLP+ +EEE+
Sbjct: 236 SVSDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEK 294
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
+I+GTADFF V +YT L+ ++ + + + D + + P W W+ ++P
Sbjct: 295 KMIKGTADFFAVQYYTTRLIKYQEN--KKGELGILQDAEIEFFPDPSWKN--VDWIYVVP 350
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VR 260
+ +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++ V
Sbjct: 351 WGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVN 410
Query: 259 LKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVIDHDL 83
L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++ L
Sbjct: 411 LQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 178 bits (434), Expect = 2e-44
Identities = 85/239 (35%), Positives = 140/239 (58%), Gaps = 1/239 (0%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
S D+ AA+ ++ PIF +G +P+ + +++A S + GYP +RLP+ +EEE+
Sbjct: 236 SVSDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEK 294
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
+I+GTADFF V +YT L+ ++ + + + D + + P W W+ ++P
Sbjct: 295 KMIKGTADFFAVQYYTTRLIKYQEN--KKGELGILQDAEIEFFPDPSWKN--VDWIYVVP 350
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VR 260
+ +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++ V
Sbjct: 351 WGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVN 410
Query: 259 LKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVIDHDL 83
L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++ L
Sbjct: 411 LQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 177 bits (431), Expect = 4e-44
Identities = 85/239 (35%), Positives = 139/239 (58%), Gaps = 1/239 (0%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
S D+ AA+ ++ PIF +G +P+ + +++A S + GYP +RLP+ +EEE+
Sbjct: 236 SVSDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEK 294
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
+I+GTADFF V +YT L+ ++ + + D + + P W W+ ++P
Sbjct: 295 KMIKGTADFFAVQYYTTRLIKYQEN--KKGELGTLQDAEIEFFPDPSWKN--VDWIYVVP 350
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VR 260
+ +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++ V
Sbjct: 351 WGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVN 410
Query: 259 LKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVIDHDL 83
L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++ L
Sbjct: 411 LQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 175 bits (425), Expect = 2e-43
Identities = 84/239 (35%), Positives = 139/239 (58%), Gaps = 1/239 (0%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
S D+ AA+ ++ PIF +G +P+ + +++A S + GYP +RLP+ +EEE+
Sbjct: 236 SVSDQEAAKRAITFHLDLFAKPIFI-DGDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEK 294
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
+I+GTADFF V + T L+ ++ + + + D + + P W W+ ++P
Sbjct: 295 KMIKGTADFFAVQYCTTRLIKYQEN--KRGELGILQDAEIEFFPDPSWKN--VDWIYVVP 350
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VR 260
+ +L ++K+ YN+P+ Y+TENG+ S L+D R Y+R + + ++ V
Sbjct: 351 WGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVN 410
Query: 259 LKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVIDHDL 83
L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++ L
Sbjct: 411 LQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAHL 469
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 173 bits (420), Expect = 8e-43
Identities = 89/230 (38%), Positives = 126/230 (54%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
++ED AA Q G + HPIF + G + + + R+ ++S G ++RLP+ +E E+
Sbjct: 1610 NQEDVEAARRYVQFMGGWFAHPIF-KNGDYSEVMKTRIRDRSLAAGLNKSRLPEFTESEK 1668
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
I GT DFFG NHYT L + S S +D V + W S + WL + P
Sbjct: 1669 RRINGTYDFFGFNHYTTVLAYNLNYATAIS--SFDADRGVASIADRSWPDSGSFWLKMTP 1726
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAGVRL 257
+L LK +YNDP YVTENG + E L D RI Y R + L ++ V L
Sbjct: 1727 FGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDL 1786
Query: 256 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 107
+GY WS MDN+EW G++ERFGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1787 RGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 145 bits (351), Expect = 2e-34
Identities = 87/229 (37%), Positives = 122/229 (53%), Gaps = 3/229 (1%)
Frame = -3
Query: 787 DRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVLI 608
D AA+ Q G + HPIF + G +P + +V +S +RLP +EEE+ I
Sbjct: 1139 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 1197
Query: 607 RGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSI 428
R TAD F +N Y +V P + S D + P W +A + P
Sbjct: 1198 RATADVFCLNTYYSRIVQ--HKTPRLNPPSYEDDQEMAEEEDPSWPSTAMN--RAAPWGT 1253
Query: 427 YDVLTHLKNKYNDPIFYVTENGWA-TSPEVGLEDDDRITYYRAALENILDS--LDAGVRL 257
+L +K +Y D Y+TENG T+P ED DRI Y++ + L + LD G+ L
Sbjct: 1254 RRLLNWIKEEYGDIPIYITENGVGLTNPNT--EDTDRIFYHKTYINEALKAYRLD-GIDL 1310
Query: 256 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
+GY+AWSLMDN+EW+ GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 1311 RGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 136 bits (329), Expect = 9e-32
Identities = 78/235 (33%), Positives = 134/235 (57%), Gaps = 8/235 (3%)
Frame = -3
Query: 790 EDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVL 611
ED A+E G + HP+F +G +P L ++ + + + +P +LP+ +E E+ L
Sbjct: 615 EDLRASERFLHFMLGWFAHPVFV-DGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQL 673
Query: 610 IRGTADFFGVNHYTGYLVSATKH---IPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLM 440
++G+ADF G++HYT L+S IP Y T+ FS +V + W Q+++SW+ ++
Sbjct: 674 LKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQ-HVNHV----WPQTSSSWIRVV 728
Query: 439 PNSIYDVLTHLKNKYND---PIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDSL- 275
P I +L + +Y PI Y+ NG L DD R+ Y+ + +L ++
Sbjct: 729 PWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIK 787
Query: 274 DAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
+ V ++ Y+A SL+D +E +GY++RFGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 788 EDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSII 842
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 172 bits (419), Expect = 1e-42
Identities = 89/230 (38%), Positives = 126/230 (54%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
++ED AA Q G + HPIF + G + + + R+ ++S G ++RLP+ +E E+
Sbjct: 1610 NQEDVEAARRYVQFMGGWFAHPIF-KNGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEK 1668
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
I GT DFFG NHYT L + S S +D V + W S + WL + P
Sbjct: 1669 RRINGTYDFFGFNHYTTVLAYNLNYATAIS--SFDADRGVASIADRSWPDSGSFWLKMTP 1726
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAGVRL 257
+L LK +YNDP YVTENG + E L D RI Y R + L ++ V L
Sbjct: 1727 FGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDL 1786
Query: 256 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 107
+GY WS MDN+EW G++ERFGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1787 RGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 145 bits (351), Expect = 2e-34
Identities = 87/229 (37%), Positives = 122/229 (53%), Gaps = 3/229 (1%)
Frame = -3
Query: 787 DRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVLI 608
D AA+ Q G + HPIF + G +P + +V +S +RLP +EEE+ I
Sbjct: 1139 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 1197
Query: 607 RGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSI 428
R TAD F +N Y +V P + S D + P W +A + P
Sbjct: 1198 RATADVFCLNTYYSRIVQ--HKTPRLNPPSYEDDQEMAEEEDPSWPSTAMN--RAAPWGT 1253
Query: 427 YDVLTHLKNKYNDPIFYVTENGWA-TSPEVGLEDDDRITYYRAALENILDS--LDAGVRL 257
+L +K +Y D Y+TENG T+P ED DRI Y++ + L + LD G+ L
Sbjct: 1254 RRLLNWIKEEYGDIPIYITENGVGLTNPNT--EDTDRIFYHKTYINEALKAYRLD-GIDL 1310
Query: 256 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
+GY+AWSLMDN+EW+ GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 1311 RGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 136 bits (329), Expect = 9e-32
Identities = 78/235 (33%), Positives = 134/235 (57%), Gaps = 8/235 (3%)
Frame = -3
Query: 790 EDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVL 611
ED A+E G + HP+F +G +P L ++ + + + +P +LP+ +E E+ L
Sbjct: 615 EDLRASERFLHFMLGWFAHPVFV-DGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQL 673
Query: 610 IRGTADFFGVNHYTGYLVSATKH---IPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLM 440
++G+ADF G++HYT L+S IP Y T+ FS +V + W Q+++SW+ ++
Sbjct: 674 LKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQ-HVNHV----WPQTSSSWIRVV 728
Query: 439 PNSIYDVLTHLKNKYND---PIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDSL- 275
P I +L + +Y PI Y+ NG L DD R+ Y+ + +L ++
Sbjct: 729 PWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIK 787
Query: 274 DAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
+ V ++ Y+A SL+D +E +GY++RFGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 788 EDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSII 842
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 172 bits (419), Expect = 1e-42
Identities = 89/230 (38%), Positives = 126/230 (54%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
++ED AA Q G + HPIF + G + + + R+ ++S G ++RLP+ +E E+
Sbjct: 1610 NQEDVEAARRYVQFMGGWFAHPIF-KNGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEK 1668
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
I GT DFFG NHYT L + S S +D V + W S + WL + P
Sbjct: 1669 RRINGTYDFFGFNHYTTVLAYNLNYATAIS--SFDADRGVASIADRSWPDSGSFWLKMTP 1726
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAGVRL 257
+L LK +YNDP YVTENG + E L D RI Y R + L ++ V L
Sbjct: 1727 FGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDL 1786
Query: 256 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 107
+GY WS MDN+EW G++ERFGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1787 RGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 145 bits (351), Expect = 2e-34
Identities = 87/229 (37%), Positives = 122/229 (53%), Gaps = 3/229 (1%)
Frame = -3
Query: 787 DRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVLI 608
D AA+ Q G + HPIF + G +P + +V +S +RLP +EEE+ I
Sbjct: 1139 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 1197
Query: 607 RGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSI 428
R TAD F +N Y +V P + S D + P W +A + P
Sbjct: 1198 RATADVFCLNTYYSRIVQ--HKTPRLNPPSYEDDQEMAEEEDPSWPSTAMN--RAAPWGT 1253
Query: 427 YDVLTHLKNKYNDPIFYVTENGWA-TSPEVGLEDDDRITYYRAALENILDS--LDAGVRL 257
+L +K +Y D Y+TENG T+P ED DRI Y++ + L + LD G+ L
Sbjct: 1254 RRLLNWIKEEYGDIPIYITENGVGLTNPNT--EDTDRIFYHKTYINEALKAYRLD-GIDL 1310
Query: 256 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
+GY+AWSLMDN+EW+ GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 1311 RGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 136 bits (329), Expect = 9e-32
Identities = 78/235 (33%), Positives = 134/235 (57%), Gaps = 8/235 (3%)
Frame = -3
Query: 790 EDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVL 611
ED A+E G + HP+F +G +P L ++ + + + +P +LP+ +E E+ L
Sbjct: 615 EDLRASERFLHFMLGWFAHPVFV-DGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQL 673
Query: 610 IRGTADFFGVNHYTGYLVSATKH---IPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLM 440
++G+ADF G++HYT L+S IP Y T+ FS +V + W Q+++SW+ ++
Sbjct: 674 LKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQ-HVNHV----WPQTSSSWIRVV 728
Query: 439 PNSIYDVLTHLKNKYND---PIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDSL- 275
P I +L + +Y PI Y+ NG L DD R+ Y+ + +L ++
Sbjct: 729 PWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIK 787
Query: 274 DAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
+ V ++ Y+A SL+D +E +GY++RFGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 788 EDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSII 842
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 145 bits (351), Expect = 2e-34
Identities = 87/229 (37%), Positives = 122/229 (53%), Gaps = 3/229 (1%)
Frame = -3
Query: 787 DRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVLI 608
D AA+ Q G + HPIF + G +P + +V +S +RLP +EEE+ I
Sbjct: 571 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 629
Query: 607 RGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSI 428
R TAD F +N Y +V P + S D + P W +A + P
Sbjct: 630 RATADVFCLNTYYSRIVQ--HKTPRLNPPSYEDDQEMAEEEDPSWPSTAMN--RAAPWGT 685
Query: 427 YDVLTHLKNKYNDPIFYVTENGWA-TSPEVGLEDDDRITYYRAALENILDS--LDAGVRL 257
+L +K +Y D Y+TENG T+P ED DRI Y++ + L + LD G+ L
Sbjct: 686 RRLLNWIKEEYGDIPIYITENGVGLTNPNT--EDTDRIFYHKTYINEALKAYRLD-GIDL 742
Query: 256 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
+GY+AWSLMDN+EW+ GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 743 RGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 791
Score = 136 bits (329), Expect = 9e-32
Identities = 78/235 (33%), Positives = 134/235 (57%), Gaps = 8/235 (3%)
Frame = -3
Query: 790 EDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVL 611
ED A+E G + HP+F +G +P L ++ + + + +P +LP+ +E E+ L
Sbjct: 47 EDLRASERFLHFMLGWFAHPVFV-DGDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQL 105
Query: 610 IRGTADFFGVNHYTGYLVSATKH---IPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLM 440
++G+ADF G++HYT L+S IP Y T+ FS +V + W Q+++SW+ ++
Sbjct: 106 LKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFSQ-HVNHV----WPQTSSSWIRVV 160
Query: 439 PNSIYDVLTHLKNKYND---PIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDSL- 275
P I +L + +Y PI Y+ NG L DD R+ Y+ + +L ++
Sbjct: 161 PWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIK 219
Query: 274 DAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
+ V ++ Y+A SL+D +E +GY++RFGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 220 EDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSII 274
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 144 bits (350), Expect = 2e-34
Identities = 76/228 (33%), Positives = 124/228 (54%), Gaps = 1/228 (0%)
Frame = -3
Query: 790 EDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVL 611
+D AAE Q G + +PI++ G +P+ + + KSAE G +RLP S +E+
Sbjct: 274 KDLEAAERYLQFCLGWFANPIYA--GDYPQVMKDYIGRKSAEQGLEMSRLPVFSLQEKSY 331
Query: 610 IRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNS 431
I+GT+DF G+ H+T ++ ++ P S +D ++ P W + WL +P
Sbjct: 332 IKGTSDFLGLGHFTTRYITE-RNYPSRQGPSYQNDRDLIELVDPNWPDLGSKWLYSVPWG 390
Query: 430 IYDVLTHLKNKYNDPIFYVTENGWATSPE-VGLEDDDRITYYRAALENILDSLDAGVRLK 254
+L + +Y DP YV ENG + L D+ RI Y + + +L ++ G +K
Sbjct: 391 FRRLLNFAQTQYGDPPIYVMENGASQKFHCTQLCDEWRIQYLKGYINEMLKAIKDGANIK 450
Query: 253 GYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
GY +WSL+D +EW GY++R+G Y V+F+D +PR P+ S YK+I+
Sbjct: 451 GYTSWSLLDKFEWEKGYSDRYGFYYVEFNDRNKPRYPKASVQYYKKII 498
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 1/110 (0%)
Frame = -3
Query: 433 SIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VRL 257
++ + L +K +YN+P + ENGW T V ED I + L +L ++ +R+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 256 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 107
GY AWSL+D +EW YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 66.9 bits (156), Expect = 8e-11
Identities = 59/205 (28%), Positives = 93/205 (45%), Gaps = 2/205 (0%)
Frame = -3
Query: 778 AAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVLIRGT 599
AAE Q E + P+F + G +P + +A K G + LP+L+E ER L++GT
Sbjct: 760 AAERFLQFEIAWFAEPLF-KTGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGT 817
Query: 598 ADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIYDV 419
DF +NH+T V + E S + + S+ + L ++P + +
Sbjct: 818 VDFCALNHFTTRFV-----MHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKL 872
Query: 418 LTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAA-LENILDS-LDAGVRLKGYM 245
L ++ Y D Y+T +G + LEDD YY L+ +L + L VR+KGY
Sbjct: 873 LRWVRRNYGDMDIYITASG---IDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYY 929
Query: 244 AWSLMDNYEWMAGYTERFGLYEVDF 170
A+ L + RFG + DF
Sbjct: 930 AFKLAEEKS-----KPRFGFFTSDF 949
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 1/110 (0%)
Frame = -3
Query: 433 SIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VRL 257
++ + L +K +YN+P + ENGW T V ED I + L +L ++ +R+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 256 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 107
GY AWSL+D +EW YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 66.9 bits (156), Expect = 8e-11
Identities = 59/205 (28%), Positives = 93/205 (45%), Gaps = 2/205 (0%)
Frame = -3
Query: 778 AAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVLIRGT 599
AAE Q E + P+F + G +P + +A K G + LP+L+E ER L++GT
Sbjct: 760 AAERFLQFEIAWFAEPLF-KTGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGT 817
Query: 598 ADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIYDV 419
DF +NH+T V + E S + + S+ + L ++P + +
Sbjct: 818 VDFCALNHFTTRFV-----MHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKL 872
Query: 418 LTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAA-LENILDS-LDAGVRLKGYM 245
L ++ Y D Y+T +G + LEDD YY L+ +L + L VR+KGY
Sbjct: 873 LRWVRRNYGDMDIYITASG---IDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYY 929
Query: 244 AWSLMDNYEWMAGYTERFGLYEVDF 170
A+ L + RFG + DF
Sbjct: 930 AFKLAEEKS-----KPRFGFFTSDF 949
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 90.2 bits (214), Expect = 7e-18
Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 1/110 (0%)
Frame = -3
Query: 433 SIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VRL 257
++ + L +K +YN+P + ENGW T V ED I + L +L ++ +R+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 256 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 107
GY AWSL+D +EW YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 66.9 bits (156), Expect = 8e-11
Identities = 59/205 (28%), Positives = 93/205 (45%), Gaps = 2/205 (0%)
Frame = -3
Query: 778 AAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVLIRGT 599
AAE Q E + P+F + G +P + +A K G + LP+L+E ER L++GT
Sbjct: 760 AAERFLQFEIAWFAEPLF-KTGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGT 817
Query: 598 ADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIYDV 419
DF +NH+T V + E S + + S+ + L ++P + +
Sbjct: 818 VDFCALNHFTTRFV-----MHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKL 872
Query: 418 LTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAA-LENILDS-LDAGVRLKGYM 245
L ++ Y D Y+T +G + LEDD YY L+ +L + L VR+KGY
Sbjct: 873 LRWVRRNYGDMDIYITASG---IDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYY 929
Query: 244 AWSLMDNYEWMAGYTERFGLYEVDF 170
A+ L + RFG + DF
Sbjct: 930 AFKLAEEKS-----KPRFGFFTSDF 949
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 77.0 bits (181), Expect = 7e-14
Identities = 33/61 (54%), Positives = 43/61 (70%)
Frame = -3
Query: 265 VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVIDHD 86
V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAH 161
Query: 85 L 83
L
Sbjct: 162 L 162
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 77.0 bits (181), Expect = 7e-14
Identities = 33/61 (54%), Positives = 43/61 (70%)
Frame = -3
Query: 265 VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVIDHD 86
V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAH 161
Query: 85 L 83
L
Sbjct: 162 L 162
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 77.0 bits (181), Expect = 7e-14
Identities = 33/61 (54%), Positives = 43/61 (70%)
Frame = -3
Query: 265 VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVIDHD 86
V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLEAH 161
Query: 85 L 83
L
Sbjct: 162 L 162
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 74.5 bits (175), Expect = 4e-13
Identities = 54/179 (30%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = -3
Query: 643 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 464
LP +E E+ I+GTADFF A P S L + P L+
Sbjct: 76 LPDFTESEKKFIKGTADFF-----------ALCFGPTLSFQLLDPHMKFRQLESPN-LRQ 123
Query: 463 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENIL 284
SW+ L ++N P ++ ENGW S +D + Y + + L
Sbjct: 124 LLSWIDL--------------EFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETL 169
Query: 283 DSLDA-GVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
++ GV + GY AWSLMD +EW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 170 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 228
Score = 70.1 bits (164), Expect = 9e-12
Identities = 69/234 (29%), Positives = 106/234 (45%), Gaps = 3/234 (1%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
S++D+ AE + + G PIF G +P + + +++ LP +E+E+
Sbjct: 469 SQKDKEVAERVLEFDIGWLAEPIFGS-GDYPWVMRDWLNQRN------NFLLPYFTEDEK 521
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
LI+GT DF ++HYT LV + K P + + V WL S S + ++P
Sbjct: 522 KLIQGTFDFLALSHYTTILVDSEKEDP----IKYNDYLEVQEMTDITWLNS-PSQVAVVP 576
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDS--LDAG 266
+ VL LK KY D Y+ NG + EDD R+ Y + + L + LD G
Sbjct: 577 WGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEALKAHILD-G 633
Query: 265 VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRS 104
+ L GY A+S D RFGLY +D P+ K Y++I+ S
Sbjct: 634 INLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKIIDS 677
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 74.5 bits (175), Expect = 4e-13
Identities = 54/179 (30%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = -3
Query: 643 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 464
LP +E E+ I+GTADFF A P S L + P L+
Sbjct: 349 LPDFTESEKKFIKGTADFF-----------ALCFGPTLSFQLLDPHMKFRQLESPN-LRQ 396
Query: 463 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENIL 284
SW+ L ++N P ++ ENGW S +D + Y + + L
Sbjct: 397 LLSWIDL--------------EFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETL 442
Query: 283 DSLDA-GVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
++ GV + GY AWSLMD +EW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 443 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 70.1 bits (164), Expect = 9e-12
Identities = 69/234 (29%), Positives = 106/234 (45%), Gaps = 3/234 (1%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
S++D+ AE + + G PIF G +P + + +++ LP +E+E+
Sbjct: 742 SQKDKEVAERVLEFDIGWLAEPIFGS-GDYPWVMRDWLNQRN------NFLLPYFTEDEK 794
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
LI+GT DF ++HYT LV + K P + + V WL S S + ++P
Sbjct: 795 KLIQGTFDFLALSHYTTILVDSEKEDP----IKYNDYLEVQEMTDITWLNS-PSQVAVVP 849
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDS--LDAG 266
+ VL LK KY D Y+ NG + EDD R+ Y + + L + LD G
Sbjct: 850 WGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEALKAHILD-G 906
Query: 265 VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRS 104
+ L GY A+S D RFGLY +D P+ K Y++I+ S
Sbjct: 907 INLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKIIDS 950
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 74.5 bits (175), Expect = 4e-13
Identities = 54/179 (30%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = -3
Query: 643 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 464
LP +E E+ I+GTADFF A P S L + P L+
Sbjct: 349 LPDFTESEKKFIKGTADFF-----------ALCFGPTLSFQLLDPHMKFRQLESPN-LRQ 396
Query: 463 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENIL 284
SW+ L ++N P ++ ENGW S +D + Y + + L
Sbjct: 397 LLSWIDL--------------EFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETL 442
Query: 283 DSLDA-GVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
++ GV + GY AWSLMD +EW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 443 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 74.5 bits (175), Expect = 4e-13
Identities = 54/179 (30%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = -3
Query: 643 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 464
LP +E E+ I+GTADFF A P S L + P L+
Sbjct: 349 LPDFTESEKKFIKGTADFF-----------ALCFGPTLSFQLLDPHMKFRQLESPN-LRQ 396
Query: 463 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENIL 284
SW+ L ++N P ++ ENGW S +D + Y + + L
Sbjct: 397 LLSWIDL--------------EFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETL 442
Query: 283 DSLDA-GVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
++ GV + GY AWSLMD +EW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 443 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 70.1 bits (164), Expect = 9e-12
Identities = 69/234 (29%), Positives = 106/234 (45%), Gaps = 3/234 (1%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
S++D+ AE + + G PIF G +P + + +++ LP +E+E+
Sbjct: 742 SQKDKEVAERVLEFDIGWLAEPIFGS-GDYPWVMRDWLNQRN------NFLLPYFTEDEK 794
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
LI+GT DF ++HYT LV + K P + + V WL S S + ++P
Sbjct: 795 KLIQGTFDFLALSHYTTILVDSEKEDP----IKYNDYLEVQEMTDITWLNS-PSQVAVVP 849
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDS--LDAG 266
+ VL LK KY D Y+ NG + EDD R+ Y + + L + LD G
Sbjct: 850 WGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEALKAHILD-G 906
Query: 265 VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRS 104
+ L GY A+S D RFGLY +D P+ K Y++I+ S
Sbjct: 907 INLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKIIDS 950
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 74.5 bits (175), Expect = 4e-13
Identities = 54/179 (30%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = -3
Query: 643 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 464
LP +E E+ I+GTADFF A P S L + P L+
Sbjct: 349 LPDFTESEKKFIKGTADFF-----------ALCFGPTLSFQLLDPHMKFRQLESPN-LRQ 396
Query: 463 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENIL 284
SW+ L ++N P ++ ENGW S +D + Y + + L
Sbjct: 397 LLSWIDL--------------EFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETL 442
Query: 283 DSLDA-GVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 110
++ GV + GY AWSLMD +EW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 443 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 70.1 bits (164), Expect = 9e-12
Identities = 69/234 (29%), Positives = 106/234 (45%), Gaps = 3/234 (1%)
Frame = -3
Query: 796 SEEDRAAAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEER 617
S++D+ AE + + G PIF G +P + + +++ LP +E+E+
Sbjct: 742 SQKDKEVAERVLEFDIGWLAEPIFGS-GDYPWVMRDWLNQRN------NFLLPYFTEDEK 794
Query: 616 VLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMP 437
LI+GT DF ++HYT LV + K P + + V WL S S + ++P
Sbjct: 795 KLIQGTFDFLALSHYTTILVDSEKEDP----IKYNDYLEVQEMTDITWLNS-PSQVAVVP 849
Query: 436 NSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENILDS--LDAG 266
+ VL LK KY D Y+ NG + EDD R+ Y + + L + LD G
Sbjct: 850 WGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEALKAHILD-G 906
Query: 265 VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRS 104
+ L GY A+S D RFGLY +D P+ K Y++I+ S
Sbjct: 907 INLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKIIDS 950
>BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein.
Length = 305
Score = 66.9 bits (156), Expect = 8e-11
Identities = 59/205 (28%), Positives = 93/205 (45%), Gaps = 2/205 (0%)
Frame = -3
Query: 778 AAELXRQAEWGIYVHPIFSQEGGFPKELVARVAEKSAEHGYPRTRLPQLSEEERVLIRGT 599
AAE Q E + P+F + G +P + +A K G + LP+L+E ER L++GT
Sbjct: 21 AAERFLQFEIAWFAEPLF-KTGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGT 78
Query: 598 ADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIYDV 419
DF +NH+T V + E S + + S+ + L ++P + +
Sbjct: 79 VDFCALNHFTTRFV-----MHEQLAGSRYDSDRDIQFLQDITRLSSPTRLAVIPWGVRKL 133
Query: 418 LTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAA-LENILDS-LDAGVRLKGYM 245
L ++ Y D Y+T +G + LEDD YY L+ +L + L VR+KGY
Sbjct: 134 LRWVRRNYGDMDIYITASG---IDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYY 190
Query: 244 AWSLMDNYEWMAGYTERFGLYEVDF 170
A+ L + RFG + DF
Sbjct: 191 AFKLAEEKS-----KPRFGFFTSDF 210
>CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein.
Length = 537
Score = 31.1 bits (67), Expect = 4.8
Identities = 18/56 (32%), Positives = 24/56 (42%)
Frame = -3
Query: 586 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIYDV 419
GVN Y L S + +Y + LF G PP+W S L P++ Y V
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPYCV 367
>U83246-1|AAC15920.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 30.7 bits (66), Expect = 6.4
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 586 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 425
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 30.7 bits (66), Expect = 6.4
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 586 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 425
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein.
Length = 386
Score = 30.7 bits (66), Expect = 6.4
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 586 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 425
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 288 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 341
>AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein.
Length = 481
Score = 30.7 bits (66), Expect = 6.4
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 586 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 425
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein.
Length = 537
Score = 30.7 bits (66), Expect = 6.4
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 586 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 425
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein.
Length = 517
Score = 30.7 bits (66), Expect = 6.4
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 586 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 425
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 292 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 345
>AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation
factor 1 variant protein.
Length = 208
Score = 30.3 bits (65), Expect = 8.4
Identities = 14/25 (56%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = -2
Query: 158 PPSHPAQV-RVRLQGDLEEQGHRPR 87
PP HPA + R R G L +GHRPR
Sbjct: 71 PPPHPASISRPRPPGPLPLRGHRPR 95
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 122,525,741
Number of Sequences: 237096
Number of extensions: 2722345
Number of successful extensions: 10058
Number of sequences better than 10.0: 31
Number of HSP's better than 10.0 without gapping: 9825
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10006
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9813323168
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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