Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV18k23f
(712 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 241 2e-63
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 241 2e-63
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 240 4e-63
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 240 4e-63
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 215 2e-55
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 210 4e-54
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 210 4e-54
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 210 4e-54
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 210 4e-54
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 202 1e-51
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 202 1e-51
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 202 1e-51
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 202 1e-51
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 202 1e-51
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 201 2e-51
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 194 3e-49
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 184 4e-46
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 184 4e-46
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 184 4e-46
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 99 2e-20
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 99 2e-20
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 98 3e-20
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 94 4e-19
BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 30 9.4
BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 30 9.4
BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA pro... 30 9.4
AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein ... 30 9.4
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 241 bits (589), Expect = 2e-63
Identities = 103/209 (49%), Positives = 140/209 (66%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
F DDFL+G ++++YQIEGAWD DGKG +IWD TH + + D + GDIA DSYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ M+R L + YRFS+SWSRI P+G + +N GVDYYNRLIN ++ NI PM++L+HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ LQ++GG+ NP + D F+ Y F GDRVK W+TFNEP + + GYGS E P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNE 710
+ Y A ++ AHA+ Y Y+ +
Sbjct: 1083 VKDPGWAPYRIAHTVIKAHARVYHTYDEK 1111
Score = 235 bits (574), Expect = 2e-61
Identities = 103/210 (49%), Positives = 145/210 (69%), Gaps = 1/210 (0%)
Frame = +3
Query: 81 RFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVER 260
RFP+ F++ A+A+YQIEGAW DGKG +IWD +H P + +++ GD+A DSYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHW 440
D+ ++ LG+ YRFS+SWSRILP G +NEAG++YY RLI+ +L +I P +++YHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
DLPQ LQ++GG+ N I F++Y V+F +LGD+VK WIT NEP V+ YQGYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -MLNATAVGTYMCARNLLLAHAKAYRLYNN 707
+ N Y+ NL+ AHA+A+ LYN+
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYND 1584
Score = 196 bits (479), Expect = 5e-50
Identities = 90/211 (42%), Positives = 131/211 (62%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNV 254
Q FP+ FL+G +T ++ +EG W E G+G +IWD N T ++ ++A+DSYH V
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTT--EGQATLEVASDSYHKV 436
Query: 255 ERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLY 434
DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + I PM +L+
Sbjct: 437 ASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLF 496
Query: 435 HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEK 614
HWDLPQ LQ+ GG+ N + D F DY F+ GDRVKLW+TF+EP V+ Y GYG+ +
Sbjct: 497 HWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQH 556
Query: 615 APMLNATAVGTYMCARNLLLAHAKAYRLYNN 707
P ++ V ++ A +L AHA+ + YN+
Sbjct: 557 PPGISDPGVASFKVAHLVLKAHARTWHHYNS 587
Score = 60.9 bits (141), Expect = 4e-09
Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Frame = +3
Query: 297 YRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWDLP-QKLQELGG 473
Y+ +SW+++LP+G +E V Y RL+ + + PM+ L+H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPMLNATAVGTYM 653
F AD F DY F GD V +W TF++ V + +A L
Sbjct: 147 F-----ADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQL--------- 192
Query: 654 CARNLLLAHAKAYRLYN 704
+ L AH KAY +Y+
Sbjct: 193 --QTLSDAHRKAYEIYH 207
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 241 bits (589), Expect = 2e-63
Identities = 103/209 (49%), Positives = 140/209 (66%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
F DDFL+G ++++YQIEGAWD DGKG +IWD TH + + D + GDIA DSYH ++ D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ M+R L + YRFS+SWSRI P+G + +N GVDYYNRLIN ++ NI PM++L+HWD
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 454
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ LQ++GG+ NP + D F+ Y F GDRVK W+TFNEP + + GYGS E P
Sbjct: 455 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 514
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNE 710
+ Y A ++ AHA+ Y Y+ +
Sbjct: 515 VKDPGWAPYRIAHTVIKAHARVYHTYDEK 543
Score = 215 bits (526), Expect = 1e-55
Identities = 92/181 (50%), Positives = 129/181 (71%)
Frame = +3
Query: 81 RFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVER 260
RFP+ F++ A+A+YQIEGAW DGKG +IWD +H P + +++ GD+A DSYH +
Sbjct: 808 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 866
Query: 261 DVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHW 440
D+ ++ LG+ YRFS+SWSRILP G +NEAG++YY RLI+ +L +I P +++YHW
Sbjct: 867 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 926
Query: 441 DLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
DLPQ LQ++GG+ N I F++Y V+F +LGD+VK WIT NEP V+ YQGYG AP
Sbjct: 927 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 986
Query: 621 M 623
+
Sbjct: 987 V 987
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 240 bits (587), Expect = 4e-63
Identities = 103/209 (49%), Positives = 140/209 (66%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
F DDFL+G ++++YQIEGAWD DGKG +IWD TH + + D + GDIA DSYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ M+R L + YRFS+SWSRI P+G + +N GVDYYNRLIN ++ NI PM++L+HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ LQ++GG+ NP + D F+ Y F GDRVK W+TFNEP + + GYGS E P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNE 710
+ Y A ++ AHA+ Y Y+ +
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEK 1111
Score = 235 bits (574), Expect = 2e-61
Identities = 103/210 (49%), Positives = 145/210 (69%), Gaps = 1/210 (0%)
Frame = +3
Query: 81 RFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVER 260
RFP+ F++ A+A+YQIEGAW DGKG +IWD +H P + +++ GD+A DSYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHW 440
D+ ++ LG+ YRFS+SWSRILP G +NEAG++YY RLI+ +L +I P +++YHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
DLPQ LQ++GG+ N I F++Y V+F +LGD+VK WIT NEP V+ YQGYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -MLNATAVGTYMCARNLLLAHAKAYRLYNN 707
+ N Y+ NL+ AHA+A+ LYN+
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYND 1584
Score = 196 bits (479), Expect = 5e-50
Identities = 90/211 (42%), Positives = 131/211 (62%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNV 254
Q FP+ FL+G +T ++ +EG W E G+G +IWD N T ++ ++A+DSYH V
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTT--EGQATLEVASDSYHKV 436
Query: 255 ERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLY 434
DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + I PM +L+
Sbjct: 437 ASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLF 496
Query: 435 HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEK 614
HWDLPQ LQ+ GG+ N + D F DY F+ GDRVKLW+TF+EP V+ Y GYG+ +
Sbjct: 497 HWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQH 556
Query: 615 APMLNATAVGTYMCARNLLLAHAKAYRLYNN 707
P ++ V ++ A +L AHA+ + YN+
Sbjct: 557 PPGISDPGVASFKVAHLVLKAHARTWHHYNS 587
Score = 60.9 bits (141), Expect = 4e-09
Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Frame = +3
Query: 297 YRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWDLP-QKLQELGG 473
Y+ +SW+++LP+G +E V Y RL+ + + PM+ L+H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPMLNATAVGTYM 653
F AD F DY F GD V +W TF++ V + +A L
Sbjct: 147 F-----ADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQL--------- 192
Query: 654 CARNLLLAHAKAYRLYN 704
+ L AH KAY +Y+
Sbjct: 193 --QTLSDAHRKAYEIYH 207
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 240 bits (587), Expect = 4e-63
Identities = 103/209 (49%), Positives = 140/209 (66%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
F DDFL+G ++++YQIEGAWD DGKG +IWD TH + + D + GDIA DSYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ M+R L + YRFS+SWSRI P+G + +N GVDYYNRLIN ++ NI PM++L+HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ LQ++GG+ NP + D F+ Y F GDRVK W+TFNEP + + GYGS E P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNE 710
+ Y A ++ AHA+ Y Y+ +
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEK 1111
Score = 235 bits (574), Expect = 2e-61
Identities = 103/210 (49%), Positives = 145/210 (69%), Gaps = 1/210 (0%)
Frame = +3
Query: 81 RFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVER 260
RFP+ F++ A+A+YQIEGAW DGKG +IWD +H P + +++ GD+A DSYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHW 440
D+ ++ LG+ YRFS+SWSRILP G +NEAG++YY RLI+ +L +I P +++YHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
DLPQ LQ++GG+ N I F++Y V+F +LGD+VK WIT NEP V+ YQGYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -MLNATAVGTYMCARNLLLAHAKAYRLYNN 707
+ N Y+ NL+ AHA+A+ LYN+
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYND 1584
Score = 196 bits (479), Expect = 5e-50
Identities = 90/211 (42%), Positives = 131/211 (62%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNV 254
Q FP+ FL+G +T ++ +EG W E G+G +IWD N T ++ ++A+DSYH V
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTT--EGQATLEVASDSYHKV 436
Query: 255 ERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLY 434
DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + I PM +L+
Sbjct: 437 ASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLF 496
Query: 435 HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEK 614
HWDLPQ LQ+ GG+ N + D F DY F+ GDRVKLW+TF+EP V+ Y GYG+ +
Sbjct: 497 HWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQH 556
Query: 615 APMLNATAVGTYMCARNLLLAHAKAYRLYNN 707
P ++ V ++ A +L AHA+ + YN+
Sbjct: 557 PPGISDPGVASFKVAHLVLKAHARTWHHYNS 587
Score = 60.9 bits (141), Expect = 4e-09
Identities = 41/137 (29%), Positives = 62/137 (45%), Gaps = 1/137 (0%)
Frame = +3
Query: 297 YRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWDLP-QKLQELGG 473
Y+ +SW+++LP+G +E V Y RL+ + + PM+ L+H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPMLNATAVGTYM 653
F AD F DY F GD V +W TF++ V + +A L
Sbjct: 147 F-----ADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQL--------- 192
Query: 654 CARNLLLAHAKAYRLYN 704
+ L AH KAY +Y+
Sbjct: 193 --QTLSDAHRKAYEIYH 207
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 215 bits (524), Expect = 2e-55
Identities = 93/209 (44%), Positives = 139/209 (66%), Gaps = 2/209 (0%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F +G +++YQ EGAWD+DGKG +IWD TH+ + D+A D Y+ V+ D
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGF-ANEVNEAGVDYYNRLINEMLKYNITPMISLYHW 440
+ ++REL ++ YRFS+SW R+LP+G A +VN+ G+++Y+ LI+ +L NITP+++L+HW
Sbjct: 97 IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156
Query: 441 DLPQKLQ-ELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKA 617
DLPQ LQ + GG+ N +A++F DY + F GDRVK WITF++PR + +GY + A
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHA 216
Query: 618 PMLNATAVGTYMCARNLLLAHAKAYRLYN 704
P L G Y A +++ AHAK + YN
Sbjct: 217 PGLKLRGTGLYKAAHHIIKAHAKTWHSYN 245
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 210 bits (513), Expect = 4e-54
Identities = 101/226 (44%), Positives = 137/226 (60%), Gaps = 16/226 (7%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESN----------- 221
Q FPD FL+ +A+YQ EG W + GKG +IWD TH+ D N
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 222 ----GDIAADSYHNVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLI 389
GD+A+DSY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYNITPMISLYHWDLPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITF 566
+ + + P+++LYHWDLPQ+LQ+ GG+AN +AD F DY + F G +VK WIT
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPRVVCYQGYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYN 704
+ P VV + GY + AP + + Y+ A NLLLAHAK + LYN
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 9/218 (4%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSY----HN 251
FP DF +G Q++ + N++ + H++ +I + SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQF-TDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAA 577
Query: 252 VERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISL 431
++ + +++E+ + +RFS+ W+ ILP G ++VN + YY + +E+++ NITP+++L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 432 Y-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQG 596
+ + LP+ L G + NP A F +Y R+ F +LG VKLWIT NEP
Sbjct: 638 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------- 690
Query: 597 YGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNE 710
T TY NLL AHA A+ +YN +
Sbjct: 691 -----------YTRNMTYSAGHNLLKAHALAWHVYNEK 717
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 210 bits (513), Expect = 4e-54
Identities = 101/226 (44%), Positives = 137/226 (60%), Gaps = 16/226 (7%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESN----------- 221
Q FPD FL+ +A+YQ EG W + GKG +IWD TH+ D N
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 222 ----GDIAADSYHNVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLI 389
GD+A+DSY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYNITPMISLYHWDLPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITF 566
+ + + P+++LYHWDLPQ+LQ+ GG+AN +AD F DY + F G +VK WIT
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPRVVCYQGYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYN 704
+ P VV + GY + AP + + Y+ A NLLLAHAK + LYN
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 210 bits (513), Expect = 4e-54
Identities = 101/226 (44%), Positives = 137/226 (60%), Gaps = 16/226 (7%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESN----------- 221
Q FPD FL+ +A+YQ EG W + GKG +IWD TH+ D N
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 222 ----GDIAADSYHNVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLI 389
GD+A+DSY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYNITPMISLYHWDLPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITF 566
+ + + P+++LYHWDLPQ+LQ+ GG+AN +AD F DY + F G +VK WIT
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPRVVCYQGYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYN 704
+ P VV + GY + AP + + Y+ A NLLLAHAK + LYN
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 9/218 (4%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSY----HN 251
FP DF +G Q++ + N++ + H++ +I + SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQF-TDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAA 577
Query: 252 VERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISL 431
++ + +++E+ + +RFS+ W+ ILP G ++VN + YY + +E+++ NITP+++L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 432 Y-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQG 596
+ + LP+ L G + NP A F +Y R+ F +LG VKLWIT NEP
Sbjct: 638 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------- 690
Query: 597 YGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNE 710
T TY NLL AHA A+ +YN +
Sbjct: 691 -----------YTRNMTYSAGHNLLKAHALAWHVYNEK 717
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 210 bits (513), Expect = 4e-54
Identities = 101/226 (44%), Positives = 137/226 (60%), Gaps = 16/226 (7%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESN----------- 221
Q FPD FL+ +A+YQ EG W + GKG +IWD TH+ D N
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 222 ----GDIAADSYHNVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLI 389
GD+A+DSY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYNITPMISLYHWDLPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITF 566
+ + + P+++LYHWDLPQ+LQ+ GG+AN +AD F DY + F G +VK WIT
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPRVVCYQGYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYN 704
+ P VV + GY + AP + + Y+ A NLLLAHAK + LYN
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYN 283
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 9/218 (4%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSY----HN 251
FP DF +G Q++ + N++ + H++ +I + SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQF-TDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAA 577
Query: 252 VERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISL 431
++ + +++E+ + +RFS+ W+ ILP G ++VN + YY + +E+++ NITP+++L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 432 Y-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQG 596
+ + LP+ L G + NP A F +Y R+ F +LG VKLWIT NEP
Sbjct: 638 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------- 690
Query: 597 YGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNE 710
T TY NLL AHA A+ +YN +
Sbjct: 691 -----------YTRNMTYSAGHNLLKAHALAWHVYNEK 717
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 202 bits (492), Expect = 1e-51
Identities = 88/208 (42%), Positives = 130/208 (62%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNN 707
+ G Y A NL+ AHA+++ Y++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDS 210
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 202 bits (492), Expect = 1e-51
Identities = 88/208 (42%), Positives = 130/208 (62%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNN 707
+ G Y A NL+ AHA+++ Y++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDS 210
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 202 bits (492), Expect = 1e-51
Identities = 88/208 (42%), Positives = 130/208 (62%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNN 707
+ G Y A NL+ AHA+++ Y++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDS 210
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 202 bits (492), Expect = 1e-51
Identities = 88/208 (42%), Positives = 130/208 (62%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNN 707
+ G Y A NL+ AHA+++ Y++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDS 210
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 202 bits (492), Expect = 1e-51
Identities = 88/208 (42%), Positives = 130/208 (62%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNN 707
+ G Y A NL+ AHA+++ Y++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDS 210
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 201 bits (490), Expect = 2e-51
Identities = 88/208 (42%), Positives = 130/208 (62%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNN 707
+ G Y A NL+ AHA+++ Y++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDS 210
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 194 bits (473), Expect = 3e-49
Identities = 94/216 (43%), Positives = 129/216 (59%), Gaps = 16/216 (7%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESN----------- 221
Q FPD FL+ +A+YQ EG W + GKG +IWD TH+ D N
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 222 ----GDIAADSYHNVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLI 389
GD+A+DSY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYNITPMISLYHWDLPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITF 566
+ + + P+++LYHWDLPQ+LQ+ GG+AN +AD F DY + F G +VK WIT
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPRVVCYQGYGSTEKAPMLNATAVGTYMCARNLLL 674
+ P VV + GY + AP + + Y+ A NLLL
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLL 273
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 184 bits (447), Expect = 4e-46
Identities = 83/208 (39%), Positives = 123/208 (59%), Gaps = 1/208 (0%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP +F +G T + Q+EG+W +DGKG +IWD+ H + ++ +NG ++DSY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ NI P+++LYHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
LP LQE GG+ N I D F DY F GDRVK WIT + P +V + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 621 MLNATAVGTYMCARNLLLAHAKAYRLYN 704
Y NL+ AH+K + YN
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 110 bits (264), Expect = 5e-24
Identities = 58/159 (36%), Positives = 91/159 (57%), Gaps = 5/159 (3%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMIS 428
N+++ +EM+ + + YRF++ W+ +LP+G + VN + YY +++E LK I+ M++
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LY-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQ 593
LY H LP+ L G+ NP A+ F+ Y + F +LGD VKLWIT NEP
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEP------ 694
Query: 594 GYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNE 710
+ + N + TY A NLL+AHA A+RLY+ +
Sbjct: 695 ----NRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQ 729
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 184 bits (447), Expect = 4e-46
Identities = 83/208 (39%), Positives = 123/208 (59%), Gaps = 1/208 (0%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP +F +G T + Q+EG+W +DGKG +IWD+ H + ++ +NG ++DSY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ NI P+++LYHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
LP LQE GG+ N I D F DY F GDRVK WIT + P +V + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 621 MLNATAVGTYMCARNLLLAHAKAYRLYN 704
Y NL+ AH+K + YN
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 110 bits (264), Expect = 5e-24
Identities = 58/159 (36%), Positives = 91/159 (57%), Gaps = 5/159 (3%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMIS 428
N+++ +EM+ + + YRF++ W+ +LP+G + VN + YY +++E LK I+ M++
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LY-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQ 593
LY H LP+ L G+ NP A+ F+ Y + F +LGD VKLWIT NEP
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEP------ 694
Query: 594 GYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNE 710
+ + N + TY A NLL+AHA A+RLY+ +
Sbjct: 695 ----NRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQ 729
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 184 bits (447), Expect = 4e-46
Identities = 83/208 (39%), Positives = 123/208 (59%), Gaps = 1/208 (0%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP +F +G T + Q+EG+W +DGKG +IWD+ H + ++ +NG ++DSY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ NI P+++LYHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
LP LQE GG+ N I D F DY F GDRVK WIT + P +V + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 621 MLNATAVGTYMCARNLLLAHAKAYRLYN 704
Y NL+ AH+K + YN
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYN 285
Score = 110 bits (264), Expect = 5e-24
Identities = 58/159 (36%), Positives = 91/159 (57%), Gaps = 5/159 (3%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMIS 428
N+++ +EM+ + + YRF++ W+ +LP+G + VN + YY +++E LK I+ M++
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LY-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQ 593
LY H LP+ L G+ NP A+ F+ Y + F +LGD VKLWIT NEP
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEP------ 694
Query: 594 GYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNE 710
+ + N + TY A NLL+AHA A+RLY+ +
Sbjct: 695 ----NRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQ 729
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 98.7 bits (235), Expect = 2e-20
Identities = 42/95 (44%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGV 368
++ +++LGL YRFS+SWSR+LP G +N+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 98.7 bits (235), Expect = 2e-20
Identities = 42/95 (44%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGV 368
++ +++LGL YRFS+SWSR+LP G +N+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 97.9 bits (233), Expect = 3e-20
Identities = 42/95 (44%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGV 368
++ +++LGL YRFS+SWSR+LP G +N+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 94.3 bits (224), Expect = 4e-19
Identities = 64/218 (29%), Positives = 107/218 (49%), Gaps = 9/218 (4%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSY----HN 251
FP DF +G Q++ + N++ + H++ +I + SY
Sbjct: 246 FPCDFAWGVVDNYIQVDTTLSQF-TDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAA 304
Query: 252 VERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISL 431
++ + +++E+ + +RFS+ W+ ILP G ++VN + YY + +E+++ NITP+++L
Sbjct: 305 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 364
Query: 432 Y-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQG 596
+ + LP+ L G + NP A F +Y R+ F +LG VKLWIT NEP
Sbjct: 365 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------- 417
Query: 597 YGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNE 710
T TY NLL AHA A+ +YN +
Sbjct: 418 -----------YTRNMTYSAGHNLLKAHALAWHVYNEK 444
>BC018698-1|AAH18698.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 29.9 bits (64), Expect = 9.4
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +3
Query: 54 SALSIKQQRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNP-TVIADESNG 224
S S+ + PD +FGT T QI+ WD + N+ ++ H+ P T IA NG
Sbjct: 349 SGCSLTCAQFHPDGLIFGTGTMDSQIK-IWDLKER-TNVANFPGHSGPITSIAFSENG 404
>BC018665-1|AAH18665.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 29.9 bits (64), Expect = 9.4
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +3
Query: 54 SALSIKQQRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNP-TVIADESNG 224
S S+ + PD +FGT T QI+ WD + N+ ++ H+ P T IA NG
Sbjct: 349 SGCSLTCAQFHPDGLIFGTGTMDSQIK-IWDLKER-TNVANFPGHSGPITSIAFSENG 404
>BC008719-1|AAH08719.1| 504|Homo sapiens PRP19/PSO4 pre-mRNA
processing factor 19 homolog (S. cerevisiae) protein.
Length = 504
Score = 29.9 bits (64), Expect = 9.4
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +3
Query: 54 SALSIKQQRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNP-TVIADESNG 224
S S+ + PD +FGT T QI+ WD + N+ ++ H+ P T IA NG
Sbjct: 349 SGCSLTCAQFHPDGLIFGTGTMDSQIK-IWDLKER-TNVANFPGHSGPITSIAFSENG 404
>AJ131186-1|CAB51857.1| 504|Homo sapiens nuclear matrix protein
NMP200 protein.
Length = 504
Score = 29.9 bits (64), Expect = 9.4
Identities = 20/58 (34%), Positives = 29/58 (50%), Gaps = 1/58 (1%)
Frame = +3
Query: 54 SALSIKQQRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNP-TVIADESNG 224
S S+ + PD +FGT T QI+ WD + N+ ++ H+ P T IA NG
Sbjct: 349 SGCSLTCAQFHPDGLIFGTGTMDSQIK-IWDLKER-TNVANFPGHSGPITSIAFSENG 404
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,025,344
Number of Sequences: 237096
Number of extensions: 2398545
Number of successful extensions: 10426
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 9812
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10390
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8287202872
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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