Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV18i08f
(813 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 135 2e-31
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 135 2e-31
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 135 2e-31
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 135 2e-31
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 112 2e-24
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 106 1e-22
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 86 1e-16
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 86 1e-16
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 86 1e-16
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 86 1e-16
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 83 9e-16
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 83 9e-16
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 63 1e-09
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 63 1e-09
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 63 1e-09
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 63 1e-09
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 63 1e-09
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 63 1e-09
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 63 1e-09
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 63 1e-09
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 58 3e-08
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 58 3e-08
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 58 3e-08
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 58 4e-08
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 57 9e-08
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 56 2e-07
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 56 2e-07
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 55 4e-07
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 54 5e-07
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 54 5e-07
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 53 1e-06
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 53 1e-06
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 53 1e-06
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 53 1e-06
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 53 1e-06
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 53 1e-06
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 53 1e-06
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 52 2e-06
U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid deh... 52 3e-06
CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein. 52 3e-06
BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta... 52 3e-06
BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta... 52 3e-06
AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta... 52 3e-06
AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta... 52 3e-06
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 52 3e-06
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 51 4e-06
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 51 4e-06
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 51 4e-06
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 51 4e-06
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 51 4e-06
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 51 4e-06
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 51 4e-06
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 51 4e-06
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 51 6e-06
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 51 6e-06
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 51 6e-06
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 51 6e-06
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 51 6e-06
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 51 6e-06
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 50 8e-06
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 50 1e-05
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 50 1e-05
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 49 2e-05
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 49 2e-05
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 48 5e-05
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 48 5e-05
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 48 5e-05
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 48 5e-05
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 48 5e-05
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 47 9e-05
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 47 9e-05
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 47 9e-05
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 47 9e-05
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 47 9e-05
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 47 9e-05
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 47 9e-05
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 47 9e-05
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 47 9e-05
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 46 1e-04
AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent 15-hydro... 46 2e-04
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 45 3e-04
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 45 4e-04
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 44 5e-04
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 44 5e-04
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 44 5e-04
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 44 5e-04
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 44 5e-04
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 44 5e-04
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 44 5e-04
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 44 5e-04
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 44 7e-04
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 43 0.001
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 43 0.001
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 43 0.001
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 43 0.001
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 43 0.001
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 42 0.002
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 42 0.002
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 42 0.002
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 42 0.002
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 42 0.002
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 42 0.002
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 42 0.002
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 42 0.002
AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase h... 42 0.002
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 42 0.002
M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase pro... 42 0.004
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 42 0.004
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 42 0.004
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 42 0.004
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 42 0.004
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 42 0.004
BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase (... 42 0.004
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 42 0.004
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 42 0.004
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 42 0.004
AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase (... 42 0.004
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 42 0.004
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 41 0.005
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 41 0.006
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 41 0.006
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 41 0.006
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 41 0.006
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 41 0.006
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 41 0.006
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 40 0.008
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 40 0.008
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 40 0.008
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 40 0.008
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 40 0.008
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 39 0.019
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 39 0.019
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 39 0.019
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 39 0.019
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 39 0.019
AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein. 39 0.019
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 39 0.019
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 39 0.019
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 39 0.019
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 39 0.025
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 39 0.025
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 39 0.025
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 39 0.025
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 39 0.025
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 39 0.025
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 39 0.025
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 38 0.033
EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3 pr... 38 0.043
CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein. 38 0.043
BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3 pr... 38 0.043
AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NAD... 38 0.043
AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3 pr... 38 0.043
AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3 va... 38 0.043
AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3 pr... 38 0.043
AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbony... 38 0.043
AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3 pr... 38 0.043
AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3 pr... 38 0.043
BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein. 38 0.057
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 37 0.075
M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein. 37 0.075
J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein. 37 0.075
EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1 pr... 37 0.075
CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein. 37 0.075
BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1 pr... 37 0.075
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 37 0.075
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 37 0.075
BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1 pr... 37 0.075
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 37 0.075
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 37 0.075
BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1 pr... 37 0.075
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 37 0.075
AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase (NAP... 37 0.075
AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1 pr... 37 0.075
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 37 0.075
AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1 pr... 37 0.075
AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase prot... 37 0.075
CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase... 37 0.100
CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase... 37 0.100
BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase... 37 0.100
BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase... 37 0.100
BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase... 37 0.100
BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein. 37 0.100
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 37 0.100
AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein. 37 0.100
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 37 0.100
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 37 0.100
AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase... 37 0.100
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 37 0.100
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 37 0.100
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 37 0.100
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 36 0.13
BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 1... 36 0.13
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 36 0.13
AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein. 36 0.13
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 36 0.13
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 36 0.13
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 36 0.13
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 36 0.13
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 36 0.13
AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein. 36 0.13
AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein. 36 0.13
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 36 0.17
AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein. 36 0.17
AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase p... 36 0.17
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 35 0.30
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.30
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 35 0.30
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 35 0.30
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 35 0.30
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.30
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 35 0.30
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 35 0.30
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 35 0.30
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 35 0.30
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 35 0.30
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 35 0.30
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 35 0.30
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 35 0.30
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 35 0.30
AY358093-1|AAQ88460.1| 152|Homo sapiens SDR1 protein. 35 0.40
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 34 0.70
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 34 0.70
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 34 0.70
AF165517-1|AAF86647.1| 223|Homo sapiens 17-beta-hydroxysteroid ... 34 0.70
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 33 1.2
X64228-1|CAA45535.1| 2090|Homo sapiens putative oncogene protein. 33 1.6
BC045620-1|AAH45620.2| 2090|Homo sapiens nucleoporin 214kDa prot... 33 1.6
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 33 1.6
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 33 1.6
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 33 1.6
AL157938-9|CAI41111.1| 2090|Homo sapiens nucleoporin 214kDa prot... 33 1.6
AL157938-8|CAI41109.1| 1684|Homo sapiens nucleoporin 214kDa prot... 33 1.6
AJ298318-1|CAC83675.1| 1349|Homo sapiens mucin 5 protein. 33 1.6
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 33 1.6
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 33 1.6
AB159230-1|BAD07398.1| 2091|Homo sapiens KIAA0023 splice variant... 33 1.6
AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 32 2.1
BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta... 32 2.8
BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta... 32 2.8
BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta... 32 2.8
AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein. 32 2.8
AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta... 32 2.8
AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta... 32 2.8
AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta... 32 2.8
AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens ... 32 2.8
AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid d... 32 2.8
AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protei... 32 2.8
AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid ... 32 2.8
BC111965-1|AAI11966.1| 863|Homo sapiens AP2 associated kinase 1... 31 3.7
BC104842-1|AAI04843.1| 863|Homo sapiens AP2 associated kinase 1... 31 3.7
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 31 3.7
BC002695-1|AAH02695.1| 474|Homo sapiens AAK1 protein protein. 31 3.7
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 31 3.7
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 31 3.7
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 31 3.7
AB028971-1|BAA83000.2| 897|Homo sapiens KIAA1048 protein protein. 31 3.7
AY444559-1|AAS68535.1| 265|Homo sapiens retinal short chain deh... 31 5.0
AJ250550-1|CAC88111.1| 341|Homo sapiens 17beta hydroxysteroid d... 31 5.0
U77700-1|AAC51648.1| 1928|Homo sapiens HsGCN1 protein. 31 6.5
D86973-1|BAA13209.2| 2675|Homo sapiens KIAA0219 protein. 31 6.5
BC071987-1|AAH71987.1| 229|Homo sapiens HSD17B7P2 protein protein. 31 6.5
AY829267-1|AAV87307.1| 229|Homo sapiens 17beta-hydroxysteroid d... 31 6.5
AC004812-3|AAC83183.1| 2392|Homo sapiens WUGSC:H_267D11.3 protein. 31 6.5
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 30 8.7
BC112935-1|AAI12936.1| 1699|Homo sapiens QSER1 protein protein. 30 8.7
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 30 8.7
AK024447-1|BAB15737.1| 145|Homo sapiens FLJ00037 protein protein. 30 8.7
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 135 bits (327), Expect = 2e-31
Identities = 81/250 (32%), Positives = 138/250 (55%), Gaps = 5/250 (2%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALHEQFEPQKTLFIQC 63
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 399
DV ++ + F V + G LD+++NNA + N+ K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 400 MGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVRVLSI 579
M KQNGG+GG ++N+SS+A L P+Y +K ++ F+ L + SGVR+ +I
Sbjct: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAI 181
Query: 580 CFGATDTPLLNGTK----LGSFDEEIDGTCVEAIQKNYPIQKMESAAKGLVEAYE-HAKS 744
C G +T +L + +G + E D ++ + K Y I A GL+ E A +
Sbjct: 182 CPGFVNTAILESIEKEENMGQYIEYKDH--IKDMIKYYGILDPPLIANGLITLIEDDALN 239
Query: 745 GDTWIITTNK 774
G ITT+K
Sbjct: 240 GAIMKITTSK 249
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 135 bits (327), Expect = 2e-31
Identities = 81/250 (32%), Positives = 138/250 (55%), Gaps = 5/250 (2%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALHEQFEPQKTLFIQC 63
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 399
DV ++ + F V + G LD+++NNA + N+ K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 400 MGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVRVLSI 579
M KQNGG+GG ++N+SS+A L P+Y +K ++ F+ L + SGVR+ +I
Sbjct: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAI 181
Query: 580 CFGATDTPLLNGTK----LGSFDEEIDGTCVEAIQKNYPIQKMESAAKGLVEAYE-HAKS 744
C G +T +L + +G + E D ++ + K Y I A GL+ E A +
Sbjct: 182 CPGFVNTAILESIEKEENMGQYIEYKDH--IKDMIKYYGILDPPLIANGLITLIEDDALN 239
Query: 745 GDTWIITTNK 774
G ITT+K
Sbjct: 240 GAIMKITTSK 249
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 135 bits (327), Expect = 2e-31
Identities = 81/250 (32%), Positives = 138/250 (55%), Gaps = 5/250 (2%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 399
DV ++ + F V + G LD+++NNA + N+ K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 400 MGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVRVLSI 579
M KQNGG+GG ++N+SS+A L P+Y +K ++ F+ L + SGVR+ +I
Sbjct: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAI 181
Query: 580 CFGATDTPLLNGTK----LGSFDEEIDGTCVEAIQKNYPIQKMESAAKGLVEAYE-HAKS 744
C G +T +L + +G + E D ++ + K Y I A GL+ E A +
Sbjct: 182 CPGFVNTAILESIEKEENMGQYIEYKDH--IKDMIKYYGILDPPLIANGLITLIEDDALN 239
Query: 745 GDTWIITTNK 774
G ITT+K
Sbjct: 240 GAIMKITTSK 249
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 135 bits (327), Expect = 2e-31
Identities = 81/250 (32%), Positives = 138/250 (55%), Gaps = 5/250 (2%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 399
DV ++ + F V + G LD+++NNA + N+ K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 400 MGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVRVLSI 579
M KQNGG+GG ++N+SS+A L P+Y +K ++ F+ L + SGVR+ +I
Sbjct: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAI 181
Query: 580 CFGATDTPLLNGTK----LGSFDEEIDGTCVEAIQKNYPIQKMESAAKGLVEAYE-HAKS 744
C G +T +L + +G + E D ++ + K Y I A GL+ E A +
Sbjct: 182 CPGFVNTAILESIEKEENMGQYIEYKDH--IKDMIKYYGILDPPLIANGLITLIEDDALN 239
Query: 745 GDTWIITTNK 774
G ITT+K
Sbjct: 240 GAIMKITTSK 249
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 112 bits (269), Expect = 2e-24
Identities = 55/161 (34%), Positives = 97/161 (60%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 399
DV ++ + F V + G LD+++NNA + N K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNK--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 400 MGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFS 522
M KQNGG+GG ++N+SS+A L P+Y +K ++ F+
Sbjct: 122 MSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFT 162
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 106 bits (254), Expect = 1e-22
Identities = 51/140 (36%), Positives = 89/140 (63%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIEI 399
DV ++ + F V + G LD+++NNA + N+ K+++K + IN+ ++++GT ++
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGVNNE--KNWEKTLQINLVSVISGTYLGLDY 121
Query: 400 MGKQNGGKGGTVLNISSVAA 459
M KQNGG+GG ++N+SS+AA
Sbjct: 122 MSKQNGGEGGIIINMSSLAA 141
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 86.2 bits (204), Expect = 1e-16
Identities = 71/199 (35%), Positives = 97/199 (48%), Gaps = 8/199 (4%)
Frame = +1
Query: 34 WKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFY 213
+ GK+V++TG GIG G+VR + G + V I D E GRALE EL P V F
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQEL-----PGAV-FI 59
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALV 372
CDVT E+ L G LD V+NNA S + +++ +++N+
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISS-VAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
T T A+ + K G V+NISS V A+ Q+ P Y TK AV + + L+E
Sbjct: 120 TLTKLALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE-- 172
Query: 550 AKSGVRVLSICFGATDTPL 606
+ GVRV I G TPL
Sbjct: 173 SPYGVRVNCISPGNIWTPL 191
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 86.2 bits (204), Expect = 1e-16
Identities = 71/199 (35%), Positives = 97/199 (48%), Gaps = 8/199 (4%)
Frame = +1
Query: 34 WKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFY 213
+ GK+V++TG GIG G+VR + G + V I D E GRALE EL P V F
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQEL-----PGAV-FI 59
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALV 372
CDVT E+ L G LD V+NNA S + +++ +++N+
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISS-VAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
T T A+ + K G V+NISS V A+ Q+ P Y TK AV + + L+E
Sbjct: 120 TLTKLALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE-- 172
Query: 550 AKSGVRVLSICFGATDTPL 606
+ GVRV I G TPL
Sbjct: 173 SPYGVRVNCISPGNIWTPL 191
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 86.2 bits (204), Expect = 1e-16
Identities = 71/199 (35%), Positives = 97/199 (48%), Gaps = 8/199 (4%)
Frame = +1
Query: 34 WKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFY 213
+ GK+V++TG GIG G+VR + G + V I D E GRALE EL P V F
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQEL-----PGAV-FI 59
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALV 372
CDVT E+ L G LD V+NNA S + +++ +++N+
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISS-VAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
T T A+ + K G V+NISS V A+ Q+ P Y TK AV + + L+E
Sbjct: 120 TLTKLALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE-- 172
Query: 550 AKSGVRVLSICFGATDTPL 606
+ GVRV I G TPL
Sbjct: 173 SPYGVRVNCISPGNIWTPL 191
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 86.2 bits (204), Expect = 1e-16
Identities = 71/199 (35%), Positives = 97/199 (48%), Gaps = 8/199 (4%)
Frame = +1
Query: 34 WKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFY 213
+ GK+V++TG GIG G+VR + G + V I D E GRALE EL P V F
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGAR-VVICDKDESGGRALEQEL-----PGAV-FI 59
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALV 372
CDVT E+ L G LD V+NNA S + +++ +++N+
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISS-VAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
T T A+ + K G V+NISS V A+ Q+ P Y TK AV + + L+E
Sbjct: 120 TLTKLALPYLRKSQ----GNVINISSLVGAIGQAQAVP-YVATKGAVTAMTKALALDE-- 172
Query: 550 AKSGVRVLSICFGATDTPL 606
+ GVRV I G TPL
Sbjct: 173 SPYGVRVNCISPGNIWTPL 191
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 83.4 bits (197), Expect = 9e-16
Identities = 55/200 (27%), Positives = 100/200 (50%), Gaps = 8/200 (4%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
ME W+ ++ L+TGA+ GIG V R ++++G+K V + L E + P +
Sbjct: 6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNI-EELAAECKSAGYPGTL 64
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTA 366
Y+CD++ EE L +F ++++ +D+ INNA +++ S +K ++NV A
Sbjct: 65 IPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLA 124
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAA--LCQSHLFPIYFGTKSAVLQFSNCIGLE 540
L T +A + M K+ G ++NI+S++ + + Y TK AV + + E
Sbjct: 125 LSICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQE 183
Query: 541 EHYAKSGVRVLSICFGATDT 600
A++ +R I G +T
Sbjct: 184 LREAQTHIRATCISPGVVET 203
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 83.4 bits (197), Expect = 9e-16
Identities = 55/200 (27%), Positives = 100/200 (50%), Gaps = 8/200 (4%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
ME W+ ++ L+TGA+ GIG V R ++++G+K V + L E + P +
Sbjct: 6 MERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNI-EELAAECKSAGYPGTL 64
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTA 366
Y+CD++ EE L +F ++++ +D+ INNA +++ S +K ++NV A
Sbjct: 65 IPYRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLA 124
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAA--LCQSHLFPIYFGTKSAVLQFSNCIGLE 540
L T +A + M K+ G ++NI+S++ + + Y TK AV + + E
Sbjct: 125 LSICTREAYQSM-KERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQE 183
Query: 541 EHYAKSGVRVLSICFGATDT 600
A++ +R I G +T
Sbjct: 184 LREAQTHIRATCISPGVVET 203
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 63.3 bits (147), Expect = 1e-09
Identities = 58/208 (27%), Positives = 95/208 (45%), Gaps = 15/208 (7%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 526 CIGLEEHYAKSGVRVLSICFGATDTPLL 609
+ + A G+RV++I G TPLL
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGTPLL 206
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 63.3 bits (147), Expect = 1e-09
Identities = 58/208 (27%), Positives = 95/208 (45%), Gaps = 15/208 (7%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 526 CIGLEEHYAKSGVRVLSICFGATDTPLL 609
+ + A G+RV++I G TPLL
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGTPLL 206
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 63.3 bits (147), Expect = 1e-09
Identities = 58/208 (27%), Positives = 95/208 (45%), Gaps = 15/208 (7%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 526 CIGLEEHYAKSGVRVLSICFGATDTPLL 609
+ + A G+RV++I G TPLL
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGTPLL 206
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 63.3 bits (147), Expect = 1e-09
Identities = 58/208 (27%), Positives = 95/208 (45%), Gaps = 15/208 (7%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 526 CIGLEEHYAKSGVRVLSICFGATDTPLL 609
+ + A G+RV++I G TPLL
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGTPLL 206
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 63.3 bits (147), Expect = 1e-09
Identities = 58/208 (27%), Positives = 95/208 (45%), Gaps = 15/208 (7%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 526 CIGLEEHYAKSGVRVLSICFGATDTPLL 609
+ + A G+RV++I G TPLL
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGTPLL 206
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 63.3 bits (147), Expect = 1e-09
Identities = 58/208 (27%), Positives = 95/208 (45%), Gaps = 15/208 (7%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 526 CIGLEEHYAKSGVRVLSICFGATDTPLL 609
+ + A G+RV++I G TPLL
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGTPLL 206
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 63.3 bits (147), Expect = 1e-09
Identities = 58/208 (27%), Positives = 95/208 (45%), Gaps = 15/208 (7%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 526 CIGLEEHYAKSGVRVLSICFGATDTPLL 609
+ + A G+RV++I G TPLL
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGTPLL 206
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 63.3 bits (147), Expect = 1e-09
Identities = 58/208 (27%), Positives = 95/208 (45%), Gaps = 15/208 (7%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
N+ MG+ GG+ G ++N +SVAA Y +K ++ +
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT- 179
Query: 526 CIGLEEHYAKSGVRVLSICFGATDTPLL 609
+ + A G+RV++I G TPLL
Sbjct: 180 -LPIARDLAPIGIRVMTIAPGLFGTPLL 206
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 58.4 bits (135), Expect = 3e-08
Identities = 49/193 (25%), Positives = 94/193 (48%), Gaps = 3/193 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALEN--ELNTKYGPNCVKFY 213
GK++++T AA GIG+ G K +A D+ E + LE + T+ + K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELEKYPGIQTRV-LDVTKKK 63
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAI 393
+ D E +E D + N G+ +++ +++ K + +++NV ++ +KA
Sbjct: 64 QIDQFANE--VERLDVLFNVAGF----VHHGTVLDCEEKDWDFSMNLNVRSMYL-MIKA- 115
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFP-IYFGTKSAVLQFSNCIGLEEHYAKSGVRV 570
+ K K G ++N+SSVA+ + + +Y TK+AV+ + + + + + G+R
Sbjct: 116 -FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD--FIQQGIRC 172
Query: 571 LSICFGATDTPLL 609
+C G DTP L
Sbjct: 173 NCVCPGTVDTPSL 185
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 58.4 bits (135), Expect = 3e-08
Identities = 49/193 (25%), Positives = 94/193 (48%), Gaps = 3/193 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALEN--ELNTKYGPNCVKFY 213
GK++++T AA GIG+ G K +A D+ E + LE + T+ + K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELEKYPGIQTRV-LDVTKKK 63
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAI 393
+ D E +E D + N G+ +++ +++ K + +++NV ++ +KA
Sbjct: 64 QIDQFASE--VERLDVLFNVAGF----VHHGTVLDCEEKDWDFSMNLNVRSMYL-MIKA- 115
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFP-IYFGTKSAVLQFSNCIGLEEHYAKSGVRV 570
+ K K G ++N+SSVA+ + + +Y TK+AV+ + + + + + G+R
Sbjct: 116 -FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD--FIQQGIRC 172
Query: 571 LSICFGATDTPLL 609
+C G DTP L
Sbjct: 173 NCVCPGTVDTPSL 185
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 58.4 bits (135), Expect = 3e-08
Identities = 49/193 (25%), Positives = 94/193 (48%), Gaps = 3/193 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALEN--ELNTKYGPNCVKFY 213
GK++++T AA GIG+ G K +A D+ E + LE + T+ + K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELEKYPGIQTRV-LDVTKKK 63
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAI 393
+ D E +E D + N G+ +++ +++ K + +++NV ++ +KA
Sbjct: 64 QIDQFANE--VERLDVLFNVAGF----VHHGTVLDCEEKDWDFSMNLNVRSMYL-MIKA- 115
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFP-IYFGTKSAVLQFSNCIGLEEHYAKSGVRV 570
+ K K G ++N+SSVA+ + + +Y TK+AV+ + + + + + G+R
Sbjct: 116 -FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAAD--FIQQGIRC 172
Query: 571 LSICFGATDTPLL 609
+C G DTP L
Sbjct: 173 NCVCPGTVDTPSL 185
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 58.0 bits (134), Expect = 4e-08
Identities = 49/193 (25%), Positives = 94/193 (48%), Gaps = 3/193 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALEN--ELNTKYGPNCVKFY 213
GK++++T AA GIG+ G K +A D+ E + LE + T+ + K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELEKYPGIQTRV-LDVTKKK 63
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAI 393
+ D E +E D + N G+ +++ +++ K + +++NV ++ +KA
Sbjct: 64 QIDQFASE--VERLDVLFNVAGF----VHHGTVLDCEEKDWDFSMNLNVRSMYL-MIKA- 115
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFP-IYFGTKSAVLQFSNCIGLEEHYAKSGVRV 570
+ K K G ++N+SSVA+ + + +Y TK+AV+ + + + + + G+R
Sbjct: 116 -FLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSLAAD--FIQQGIRC 172
Query: 571 LSICFGATDTPLL 609
+C G DTP L
Sbjct: 173 NCVCPGTVDTPSL 185
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 56.8 bits (131), Expect = 9e-08
Identities = 55/203 (27%), Positives = 91/203 (44%), Gaps = 7/203 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+IVLITGA SG+G ++ L R + + D+ ++ G ++ + G V+ Y C
Sbjct: 40 GEIVLITGAGSGLGR-LLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVRAYTC 97
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQIDINVTALVTGT 381
D + +E + D VK E G + ++INNA I+ + +K D+N A + T
Sbjct: 98 DCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHL-WT 156
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK-S 558
KA + G ++ ISS A L + Y +K A F+ + +E K
Sbjct: 157 YKA--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK 214
Query: 559 GVRVLSICFGATDTPLLNGTKLG 627
G++ +C T + G G
Sbjct: 215 GIKTTIVCPFFIKTGMFEGCTTG 237
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 56.0 bits (129), Expect = 2e-07
Identities = 55/203 (27%), Positives = 90/203 (44%), Gaps = 7/203 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+IVLITGA SG+G ++ L R + + D+ ++ G ++ + G V Y C
Sbjct: 40 GEIVLITGAGSGLGR-LLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVHAYTC 97
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQIDINVTALVTGT 381
D + +E + D VK E G + ++INNA I+ + +K D+N A + T
Sbjct: 98 DCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHL-WT 156
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK-S 558
KA + G ++ ISS A L + Y +K A F+ + +E K
Sbjct: 157 YKA--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK 214
Query: 559 GVRVLSICFGATDTPLLNGTKLG 627
G++ +C T + G G
Sbjct: 215 GIKTTIVCPFFIKTGMFEGCTTG 237
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 56.0 bits (129), Expect = 2e-07
Identities = 55/203 (27%), Positives = 90/203 (44%), Gaps = 7/203 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+IVLITGA SG+G ++ L R + + D+ ++ G ++ + G V Y C
Sbjct: 40 GEIVLITGAGSGLGR-LLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVHAYTC 97
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQIDINVTALVTGT 381
D + +E + D VK E G + ++INNA I+ + +K D+N A + T
Sbjct: 98 DCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHL-WT 156
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK-S 558
KA + G ++ ISS A L + Y +K A F+ + +E K
Sbjct: 157 YKA--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK 214
Query: 559 GVRVLSICFGATDTPLLNGTKLG 627
G++ +C T + G G
Sbjct: 215 GIKTTIVCPFFIKTGMFEGCTTG 237
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 54.8 bits (126), Expect = 4e-07
Identities = 52/188 (27%), Positives = 86/188 (45%), Gaps = 7/188 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+IVLITGA SG+G ++ L R + + D+ ++ G ++ + G V Y C
Sbjct: 40 GEIVLITGAGSGLGR-LLALQFARLGSVLVLWDINKE-GNEETCKMAREAGATRVHAYTC 97
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQIDINVTALVTGT 381
D + +E + D VK E G + ++INNA I+ + +K D+N A + T
Sbjct: 98 DCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHL-WT 156
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK-S 558
KA + G ++ ISS A L + Y +K A F+ + +E K
Sbjct: 157 YKA--FLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQK 214
Query: 559 GVRVLSIC 582
G++ +C
Sbjct: 215 GIKTTIVC 222
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 54.4 bits (125), Expect = 5e-07
Identities = 51/193 (26%), Positives = 91/193 (47%), Gaps = 13/193 (6%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ ++TG+ GIG+ + + G+K V ++ ++D + +E+ K+ K
Sbjct: 50 GEWAVVTGSTDGIGKSYAEELAKHGMK-VVLISRSKDKLDQVSSEIKEKF-----KVETR 103
Query: 220 DVTVEELFLELFDTVKNEQGYLDV--VINNAAIMNDSYKSY-----------KKQIDINV 360
+ V+ +++D +K L++ ++NN M+ Y Y KK I+IN+
Sbjct: 104 TIAVDFASEDIYDKIKTGLAGLEIGILVNNVG-MSYEYPEYFLDVPDLDNVIKKMININI 162
Query: 361 TALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
++ T + M +++ G +LNISS + + L IY TK+ V FS C L
Sbjct: 163 LSVCKMTQLVLPGMVERSKG---AILNISSGSGMLPVPLLTIYSATKTFVDFFSQC--LH 217
Query: 541 EHYAKSGVRVLSI 579
E Y GV V S+
Sbjct: 218 EEYRSKGVFVQSV 230
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 54.4 bits (125), Expect = 5e-07
Identities = 51/193 (26%), Positives = 91/193 (47%), Gaps = 13/193 (6%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ ++TG+ GIG+ + + G+K V ++ ++D + +E+ K+ K
Sbjct: 50 GEWAVVTGSTDGIGKSYAEELAKHGMK-VVLISRSKDKLDQVSSEIKEKF-----KVETR 103
Query: 220 DVTVEELFLELFDTVKNEQGYLDV--VINNAAIMNDSYKSY-----------KKQIDINV 360
+ V+ +++D +K L++ ++NN M+ Y Y KK I+IN+
Sbjct: 104 TIAVDFASEDIYDKIKTGLAGLEIGILVNNVG-MSYEYPEYFLDVPDLDNVIKKMININI 162
Query: 361 TALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
++ T + M +++ G +LNISS + + L IY TK+ V FS C L
Sbjct: 163 LSVCKMTQLVLPGMVERSKG---AILNISSGSGMLPVPLLTIYSATKTFVDFFSQC--LH 217
Query: 541 EHYAKSGVRVLSI 579
E Y GV V S+
Sbjct: 218 EEYRSKGVFVQSV 230
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 53.2 bits (122), Expect = 1e-06
Identities = 53/194 (27%), Positives = 89/194 (45%), Gaps = 8/194 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-VKFYKC 219
K+ L+T + GIG + R + + G HV + + + ++ + T G V C
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 88
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 378
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 89 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 149 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 203
Query: 559 GVRVLSICFGATDT 600
+RV + G T
Sbjct: 204 NIRVNCLAPGLIKT 217
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 53.2 bits (122), Expect = 1e-06
Identities = 53/194 (27%), Positives = 89/194 (45%), Gaps = 8/194 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-VKFYKC 219
K+ L+T + GIG + R + + G HV + + + ++ + T G V C
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 88
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 378
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 89 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 149 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 203
Query: 559 GVRVLSICFGATDT 600
+RV + G T
Sbjct: 204 NIRVNCLAPGLIKT 217
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 53.2 bits (122), Expect = 1e-06
Identities = 53/194 (27%), Positives = 89/194 (45%), Gaps = 8/194 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-VKFYKC 219
K+ L+T + GIG + R + + G HV + + + ++ + T G V C
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 88
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 378
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 89 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 149 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 203
Query: 559 GVRVLSICFGATDT 600
+RV + G T
Sbjct: 204 NIRVNCLAPGLIKT 217
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 53.2 bits (122), Expect = 1e-06
Identities = 53/194 (27%), Positives = 89/194 (45%), Gaps = 8/194 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-VKFYKC 219
K+ L+T + GIG + R + + G HV + + + ++ + T G V C
Sbjct: 15 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 70
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 378
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 71 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 130
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 131 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 185
Query: 559 GVRVLSICFGATDT 600
+RV + G T
Sbjct: 186 NIRVNCLAPGLIKT 199
>Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 169
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 15/158 (9%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAA 459
N+ MG+ GG+ G ++N +SVAA
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA 158
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 15/158 (9%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAA 459
N+ MG+ GG+ G ++N +SVAA
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA 158
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 52.8 bits (121), Expect = 1e-06
Identities = 46/158 (29%), Positives = 74/158 (46%), Gaps = 15/158 (9%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S KG + +ITG ASG+G ++ +G V +LD+ G A +L G NCV F
Sbjct: 7 SVKGLVAVITGGASGLGLATAERLVGQGASAV-LLDLPNSGGEAQAKKL----GNNCV-F 60
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY----------KSYKKQIDI 354
DVT E+ K + G +DV +N A A+ + +Y + +++ +D+
Sbjct: 61 APADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDV 120
Query: 355 NVTALVTGTLKAIEIMGK---QNGGKGGTVLNISSVAA 459
N+ MG+ GG+ G ++N +SVAA
Sbjct: 121 NLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAA 158
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 52.4 bits (120), Expect = 2e-06
Identities = 53/194 (27%), Positives = 89/194 (45%), Gaps = 8/194 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-VKFYKC 219
K+ L+T + GIG + R + + G HV + + + ++ + T G V C
Sbjct: 33 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 88
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 378
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 89 MVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 149 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 203
Query: 559 GVRVLSICFGATDT 600
+RV + G T
Sbjct: 204 NIRVNCLAPGLIKT 217
>U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 3 protein.
Length = 310
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G + VK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTGRS-VKIIQA 105
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 387
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 388 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
+++ K + G +LNISS AL L+ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein.
Length = 310
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G + VK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTGRS-VKIIQA 105
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 387
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 388 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
+++ K + G +LNISS AL L+ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 260
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G + VK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTGRS-VKIIQA 105
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 387
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 388 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
+++ K + G +LNISS AL L+ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G + VK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTGRS-VKIIQA 105
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 387
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 388 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
+++ K + G +LNISS AL L+ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G + VK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTGRS-VKIIQA 105
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 387
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 388 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
+++ K + G +LNISS AL L+ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 51.6 bits (118), Expect = 3e-06
Identities = 45/177 (25%), Positives = 86/177 (48%), Gaps = 5/177 (2%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +ITGA GIG+ + +RG+ V I E A+ E+ G + VK +
Sbjct: 48 GQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKL-EAIATEIERTTGRS-VKIIQA 105
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALV----TGTLK 387
D T ++++ + + + + + +++NN ++ + S+ + +L+ T +K
Sbjct: 106 DFTKDDIYEHIKEKLAGLE--IGILVNNVGMLPNLLPSHFLNAPDEIQSLIHCNITSVVK 163
Query: 388 AIEIMGKQ-NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
+++ K + G +LNISS AL L+ +Y +K+ V FS + EE+ AK
Sbjct: 164 MTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSKAL-QEEYKAK 219
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 51.6 bits (118), Expect = 3e-06
Identities = 53/194 (27%), Positives = 88/194 (45%), Gaps = 8/194 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-VKFYKC 219
K+ L T + GIG + R + + G HV + + + ++ + T G V C
Sbjct: 33 KVALATASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 88
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAA-------IMNDSYKSYKKQIDINVTALVTG 378
V E L T G +D++++NAA IM+ + + + K +DINV A
Sbjct: 89 HVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPALM 148
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 149 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 203
Query: 559 GVRVLSICFGATDT 600
+RV + G T
Sbjct: 204 NIRVNCLAPGLIKT 217
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 393
D++ + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFPIYF 492
++ K ++N+SS+A HL I+F
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA----HHLGRIHF 187
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 393
D++ + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFPIYF 492
++ K ++N+SS+A HL I+F
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA----HHLGRIHF 187
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 393
D++ + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFPIYF 492
++ K ++N+SS+A HL I+F
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA----HHLGRIHF 187
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 393
D++ + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFPIYF 492
++ K ++N+SS+A HL I+F
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA----HHLGRIHF 187
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 393
D++ + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFPIYF 492
++ K ++N+SS+A HL I+F
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA----HHLGRIHF 187
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 393
D++ + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFPIYF 492
++ K ++N+SS+A HL I+F
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA----HHLGRIHF 187
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 393
D++ + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFPIYF 492
++ K ++N+SS+A HL I+F
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA----HHLGRIHF 187
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 51.2 bits (117), Expect = 4e-06
Identities = 41/153 (26%), Positives = 73/153 (47%), Gaps = 2/153 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 393
D++ + E+ +L V+INNA +M Y ++++ G L
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHIGVNHLGHFLLTH 158
Query: 394 EIMGKQNGGKGGTVLNISSVAALCQSHLFPIYF 492
++ K ++N+SS+A HL I+F
Sbjct: 159 LLLEKLKESAPSRIVNVSSLA----HHLGRIHF 187
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 50.8 bits (116), Expect = 6e-06
Identities = 56/216 (25%), Positives = 97/216 (44%), Gaps = 9/216 (4%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 375
+CDV ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 376 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 550 AKSGVRVLSICFGATDT--PLLNGTKLGSFDEEIDG 651
K G+R I G T G+F++E+ G
Sbjct: 229 GKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIG 264
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 50.8 bits (116), Expect = 6e-06
Identities = 56/216 (25%), Positives = 97/216 (44%), Gaps = 9/216 (4%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 375
+CDV ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 376 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 550 AKSGVRVLSICFGATDT--PLLNGTKLGSFDEEIDG 651
K G+R I G T G+F++E+ G
Sbjct: 229 GKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIG 264
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 50.8 bits (116), Expect = 6e-06
Identities = 56/216 (25%), Positives = 97/216 (44%), Gaps = 9/216 (4%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 375
+CDV ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 376 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 550 AKSGVRVLSICFGATDT--PLLNGTKLGSFDEEIDG 651
K G+R I G T G+F++E+ G
Sbjct: 229 GKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIG 264
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 50.8 bits (116), Expect = 6e-06
Identities = 56/216 (25%), Positives = 97/216 (44%), Gaps = 9/216 (4%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 375
+CDV ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 376 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 550 AKSGVRVLSICFGATDT--PLLNGTKLGSFDEEIDG 651
K G+R I G T G+F++E+ G
Sbjct: 229 GKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIG 264
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 50.8 bits (116), Expect = 6e-06
Identities = 56/216 (25%), Positives = 97/216 (44%), Gaps = 9/216 (4%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 375
+CDV ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 376 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 550 AKSGVRVLSICFGATDT--PLLNGTKLGSFDEEIDG 651
K G+R I G T G+F++E+ G
Sbjct: 229 GKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIG 264
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 50.8 bits (116), Expect = 6e-06
Identities = 56/216 (25%), Positives = 97/216 (44%), Gaps = 9/216 (4%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVT----- 375
+CDV ++ + G+ ++VINNAA ++ S +++ N +T
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA---GNFISPTERLSPNAWKTITDIVLN 170
Query: 376 GTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
GT +GKQ KG L+I+++ A S K+ V S + E +
Sbjct: 171 GTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKSLAAE--W 228
Query: 550 AKSGVRVLSICFGATDT--PLLNGTKLGSFDEEIDG 651
K G+R I G T G+F++E+ G
Sbjct: 229 GKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIG 264
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 50.4 bits (115), Expect = 8e-06
Identities = 51/194 (26%), Positives = 88/194 (45%), Gaps = 8/194 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-VKFYKC 219
K+ L+T + GIG + R + + G HV + + + ++ + T G V C
Sbjct: 15 KVALVTASTDGIGFAIARRLAQDGA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 70
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI-------MNDSYKSYKKQIDINVTALVTG 378
V E L G +D++++NAA+ M+ + + + K +DINV A
Sbjct: 71 HVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALM 130
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
T + M K+ GG+V+ +SS+AA S F Y +K+A+L + + +E A
Sbjct: 131 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIE--LAPR 185
Query: 559 GVRVLSICFGATDT 600
+RV + G T
Sbjct: 186 NIRVNCLAPGLIKT 199
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 2/141 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V+ITGA +GIG+ R + RG + ++A DV + A E ++TK V+ K
Sbjct: 39 GKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVR--K 96
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAIE 396
D++ + + E+ L ++INNA +M Y + ++ G
Sbjct: 97 LDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTY 156
Query: 397 IMGKQ-NGGKGGTVLNISSVA 456
++ +Q V+N+SSVA
Sbjct: 157 LLLEQLKVSAPARVVNVSSVA 177
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 50.0 bits (114), Expect = 1e-05
Identities = 39/141 (27%), Positives = 67/141 (47%), Gaps = 2/141 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V+ITGA +GIG+ R + RG + ++A DV + A E ++TK V+ K
Sbjct: 39 GKVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNSQVLVR--K 96
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAI 393
D++ + + E+ L ++INNA +M Y + ++ G L
Sbjct: 97 LDLSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTADGFETHLGVNHLGHFLLTY 156
Query: 394 EIMGKQNGGKGGTVLNISSVA 456
++ + V+N+SSVA
Sbjct: 157 LLLERLKVSAPARVVNVSSVA 177
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 48.8 bits (111), Expect = 2e-05
Identities = 30/108 (27%), Positives = 55/108 (50%), Gaps = 1/108 (0%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVK-HVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
GK+V++TGA +GIG+ + + +RG + ++A DV + G + E+ T G V K
Sbjct: 41 GKVVVVTGANTGIGKETAKELAQRGARVYLACRDV--EKGELVAKEIQTTTGNQQVLVRK 98
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINV 360
D++ + E+ +L V+INNA +M Y ++++
Sbjct: 99 LDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTADGFEMHI 146
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 48.8 bits (111), Expect = 2e-05
Identities = 46/174 (26%), Positives = 81/174 (46%), Gaps = 8/174 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-VKFYKC 219
K+ L+T + GIG + R + + HV + + + ++ + T G V C
Sbjct: 31 KVALVTASTDGIGFAIARRLAQDRA-HVVVSSRKQQN---VDQAVATLQGEGLSVTGTVC 86
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI-------MNDSYKSYKKQIDINVTALVTG 378
V E L G +D++++NAA+ M+ + + + K +DINV A
Sbjct: 87 HVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALM 146
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
T + M K+ GG+V+ +SS+AA S F Y +K+A+L +N + +E
Sbjct: 147 TKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIE 197
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 47.6 bits (108), Expect = 5e-05
Identities = 54/211 (25%), Positives = 93/211 (44%), Gaps = 11/211 (5%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHV----AILDVAEDSGRALENELNTKYGPNCVKFY 213
+V +TGA+SGIGE + + + GV V + ++ R LEN N K +
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENG-NLK--EKDILVL 108
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVT 375
D+T V E G +D+++NN + M+ S Y+K I++N V+
Sbjct: 109 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 168
Query: 376 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
T + M ++ GK ++ ++S+ + L Y +K A+ F N GL A
Sbjct: 169 LTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFN--GLRTELAT 223
Query: 556 -SGVRVLSICFGATDTPLLNGTKLGSFDEEI 645
G+ V +IC G + ++ + G + I
Sbjct: 224 YPGIIVSNICPGPVQSNIVENSLAGEVTKTI 254
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 47.6 bits (108), Expect = 5e-05
Identities = 54/211 (25%), Positives = 93/211 (44%), Gaps = 11/211 (5%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHV----AILDVAEDSGRALENELNTKYGPNCVKFY 213
+V +TGA+SGIGE + + + GV V + ++ R LEN N K +
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENG-NLK--EKDILVL 108
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVT 375
D+T V E G +D+++NN + M+ S Y+K I++N V+
Sbjct: 109 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 168
Query: 376 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
T + M ++ GK ++ ++S+ + L Y +K A+ F N GL A
Sbjct: 169 LTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFN--GLRTELAT 223
Query: 556 -SGVRVLSICFGATDTPLLNGTKLGSFDEEI 645
G+ V +IC G + ++ + G + I
Sbjct: 224 YPGIIVSNICPGPVQSNIVENSLAGEVTKTI 254
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 47.6 bits (108), Expect = 5e-05
Identities = 54/211 (25%), Positives = 93/211 (44%), Gaps = 11/211 (5%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHV----AILDVAEDSGRALENELNTKYGPNCVKFY 213
+V +TGA+SGIGE + + + GV V + ++ R LEN N K +
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENG-NLK--EKDILVL 58
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVT 375
D+T V E G +D+++NN + M+ S Y+K I++N V+
Sbjct: 59 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 118
Query: 376 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
T + M ++ GK ++ ++S+ + L Y +K A+ F N GL A
Sbjct: 119 LTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFN--GLRTELAT 173
Query: 556 -SGVRVLSICFGATDTPLLNGTKLGSFDEEI 645
G+ V +IC G + ++ + G + I
Sbjct: 174 YPGIIVSNICPGPVQSNIVENSLAGEVTKTI 204
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 47.6 bits (108), Expect = 5e-05
Identities = 54/211 (25%), Positives = 93/211 (44%), Gaps = 11/211 (5%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHV----AILDVAEDSGRALENELNTKYGPNCVKFY 213
+V +TGA+SGIGE + + + GV V + ++ R LEN N K +
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENG-NLK--EKDILVL 108
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVT 375
D+T V E G +D+++NN + M+ S Y+K I++N V+
Sbjct: 109 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 168
Query: 376 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
T + M ++ GK ++ ++S+ + L Y +K A+ F N GL A
Sbjct: 169 LTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFN--GLRTELAT 223
Query: 556 -SGVRVLSICFGATDTPLLNGTKLGSFDEEI 645
G+ V +IC G + ++ + G + I
Sbjct: 224 YPGIIVSNICPGPVQSNIVENSLAGEVTKTI 254
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 47.6 bits (108), Expect = 5e-05
Identities = 54/211 (25%), Positives = 93/211 (44%), Gaps = 11/211 (5%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHV----AILDVAEDSGRALENELNTKYGPNCVKFY 213
+V +TGA+SGIGE + + + GV V + ++ R LEN N K +
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENG-NLK--EKDILVL 58
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVT 375
D+T V E G +D+++NN + M+ S Y+K I++N V+
Sbjct: 59 PLDLTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVS 118
Query: 376 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
T + M ++ GK ++ ++S+ + L Y +K A+ F N GL A
Sbjct: 119 LTKCVLPHMIERKQGK---IVTVNSILGIISVPLSIGYCASKHALRGFFN--GLRTELAT 173
Query: 556 -SGVRVLSICFGATDTPLLNGTKLGSFDEEI 645
G+ V +IC G + ++ + G + I
Sbjct: 174 YPGIIVSNICPGPVQSNIVENSLAGEVTKTI 204
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 46.8 bits (106), Expect = 9e-05
Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G++ ++TGA+ GIG G+ + + G V I D+ R + E + G CV C
Sbjct: 7 GQVCVVTGASRGIGRGIALQLCKAGAT-VYITGRHLDTLRVVAQEAQS-LGGQCVPVV-C 63
Query: 220 DVTVEELFLELFDTV-KNEQGYLDVVINNA 306
D + E LF+ V + +QG LDV++NNA
Sbjct: 64 DSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/90 (28%), Positives = 45/90 (50%)
Frame = +1
Query: 49 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDVT 228
VLITG GIG + R ERG + + + E + E+ + G C ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTEC-HYFICDVG 98
Query: 229 VEELFLELFDTVKNEQGYLDVVINNAAIMN 318
E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/90 (28%), Positives = 45/90 (50%)
Frame = +1
Query: 49 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDVT 228
VLITG GIG + R ERG + + + E + E+ + G C ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTEC-HYFICDVG 98
Query: 229 VEELFLELFDTVKNEQGYLDVVINNAAIMN 318
E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/90 (28%), Positives = 45/90 (50%)
Frame = +1
Query: 49 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDVT 228
VLITG GIG + R ERG + + + E + E+ + G C ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTEC-HYFICDVG 98
Query: 229 VEELFLELFDTVKNEQGYLDVVINNAAIMN 318
E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/90 (28%), Positives = 45/90 (50%)
Frame = +1
Query: 49 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDVT 228
VLITG GIG + R ERG + + + E + E+ + G C ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTEC-HYFICDVG 98
Query: 229 VEELFLELFDTVKNEQGYLDVVINNAAIMN 318
E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 46.8 bits (106), Expect = 9e-05
Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G++ ++TGA+ GIG G+ + + G V I D+ R + E + G CV C
Sbjct: 7 GQVCVVTGASRGIGRGIALQLCKAGAT-VYITGRHLDTLRVVAQEAQS-LGGQCVPVV-C 63
Query: 220 DVTVEELFLELFDTV-KNEQGYLDVVINNA 306
D + E LF+ V + +QG LDV++NNA
Sbjct: 64 DSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 46.8 bits (106), Expect = 9e-05
Identities = 31/90 (34%), Positives = 48/90 (53%), Gaps = 1/90 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G++ ++TGA+ GIG G+ + + G V I D+ R + E + G CV C
Sbjct: 7 GQVCVVTGASRGIGRGIALQLCKAGAT-VYITGRHLDTLRVVAQEAQS-LGGQCVPVV-C 63
Query: 220 DVTVEELFLELFDTV-KNEQGYLDVVINNA 306
D + E LF+ V + +QG LDV++NNA
Sbjct: 64 DSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/90 (28%), Positives = 45/90 (50%)
Frame = +1
Query: 49 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDVT 228
VLITG GIG + R ERG + + + E + E+ + G C ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTEC-HYFICDVG 98
Query: 229 VEELFLELFDTVKNEQGYLDVVINNAAIMN 318
E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 46.8 bits (106), Expect = 9e-05
Identities = 26/90 (28%), Positives = 45/90 (50%)
Frame = +1
Query: 49 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDVT 228
VLITG GIG + R ERG + + + E + E+ + G C ++ CDV
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTEC-HYFICDVG 98
Query: 229 VEELFLELFDTVKNEQGYLDVVINNAAIMN 318
E + V+ + G + +++NNAA+++
Sbjct: 99 NREEVYQTAKAVREKVGDITILVNNAAVVH 128
>AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 188
Score = 46.4 bits (105), Expect = 1e-04
Identities = 28/93 (30%), Positives = 50/93 (53%)
Frame = +1
Query: 31 SWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKF 210
S++GK+ ITG +G+G+G+ L+ G + V I D +A +++++ G N V
Sbjct: 56 SFQGKVAFITGGGTGLGKGMTTLLSSLGAQCV-IASRKMDVLKATAEQISSQTG-NKVHA 113
Query: 211 YKCDVTVEELFLELFDTVKNEQGYLDVVINNAA 309
+CDV ++ + G+ ++VINNAA
Sbjct: 114 IQCDVRDPDMVQNTVSELIKVAGHPNIVINNAA 146
>AF177983-1|AAF29493.1| 72|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 72
Score = 46.0 bits (104), Expect = 2e-04
Identities = 23/66 (34%), Positives = 38/66 (57%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
GK+ L+TGAA GIG +L +G K VA++D ++G + L+ ++ P F +C
Sbjct: 5 GKVALVTGAAQGIGRAFAEALLLKGAK-VALVDWNLEAGVQCKAALDEQFEPQKTLFIQC 63
Query: 220 DVTVEE 237
DV ++
Sbjct: 64 DVADQQ 69
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 45.2 bits (102), Expect = 3e-04
Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 1/90 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ ++TGA+ GIG G+ + + G V I D+ R + E + G CV C
Sbjct: 7 GQACVVTGASRGIGRGIALQLCKAGAT-VYITGRHLDTLRVVAQEAQS-LGGQCVPVV-C 63
Query: 220 DVTVEELFLELFDTV-KNEQGYLDVVINNA 306
D + E LF+ V + +QG LDV++NNA
Sbjct: 64 DSSQESEVRSLFEQVDREQQGRLDVLVNNA 93
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 44.8 bits (101), Expect = 4e-04
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ VL+TGA GIG G V+ + G + VA+ D +L E P CV
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD-SLVREC-PGIEPVCVDLGDW 64
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 381
+ T L G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 65 EATERAL---------GSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIAARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ VL+TGA GIG G V+ + G + VA+ D +L E P CV
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD-SLVREC-PGIEPVCVDLGDW 64
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 381
+ T L G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 65 EATERAL---------GSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ VL+TGA GIG G V+ + G + VA+ D +L E P CV
Sbjct: 6 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD-SLVREC-PGIEPVCVDLGDW 63
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 381
+ T L G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 64 EATERAL---------GSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 112
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 113 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 165
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ VL+TGA GIG G V+ + G + VA+ D +L E P CV
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD-SLVREC-PGIEPVCVDLGDW 64
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 381
+ T L G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 65 EATERAL---------GSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ VL+TGA GIG G V+ + G + VA+ D +L E P CV
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD-SLVREC-PGIEPVCVDLGDW 64
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 381
+ T L G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 65 EATERAL---------GSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ VL+TGA GIG G V+ + G + VA+ D +L E P CV
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD-SLVREC-PGIEPVCVDLGDW 64
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 381
+ T L G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 65 EATERAL---------GSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ VL+TGA GIG G V+ + G + VA+ D +L E P CV
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD-SLVREC-PGIEPVCVDLGDW 64
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 381
+ T L G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 65 EATERAL---------GSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ VL+TGA GIG G V+ + G + VA+ D +L E P CV
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD-SLVREC-PGIEPVCVDLGDW 64
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 381
+ T L G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 65 EATERAL---------GSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 44.4 bits (100), Expect = 5e-04
Identities = 43/173 (24%), Positives = 76/173 (43%), Gaps = 6/173 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ VL+TGA GIG G V+ + G + VA+ D +L E P CV
Sbjct: 7 GRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD-SLVREC-PGIEPVCVDLGDW 64
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI------MNDSYKSYKKQIDINVTALVTGT 381
+ T L G +D+++NNAA+ + + +++ + ++N+ A++
Sbjct: 65 EATERAL---------GSVGPVDLLVNNAAVALLQPFLEVTKEAFDRSFEVNLRAVI--Q 113
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
+ I G G G ++N+SS + +Y TK A+ + + LE
Sbjct: 114 VSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALE 166
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 44.0 bits (99), Expect = 7e-04
Identities = 42/157 (26%), Positives = 70/157 (44%), Gaps = 15/157 (9%)
Frame = +1
Query: 184 KYGPNCVKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNA--AIMNDSY---------- 327
K G NCV F DVT E+ K + G +DV +N A A+ + +Y
Sbjct: 3 KLGNNCV-FAPADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTL 61
Query: 328 KSYKKQIDINVTALVTGTLKAIEIMGKQN---GGKGGTVLNISSVAALCQSHLFPIYFGT 498
+ +++ +D+N+ MG+ GG+ G ++N +SVAA Y +
Sbjct: 62 EDFQRVLDVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSAS 121
Query: 499 KSAVLQFSNCIGLEEHYAKSGVRVLSICFGATDTPLL 609
K ++ + + + A G+RV++I G TPLL
Sbjct: 122 KGGIVGMT--LPIARDLAPIGIRVMTIAPGLFGTPLL 156
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/199 (23%), Positives = 88/199 (44%), Gaps = 8/199 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVK 207
E +GK V++TGA+ GIG + + + G HV V S L+ ++
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGA-HVV---VTARSKETLQKVVSHCLELGAAS 85
Query: 208 FYKCDVTVEEL-FLELFDTVKNE-QGYLDVVINN------AAIMNDSYKSYKKQIDINVT 363
+ T+E++ F E F + G LD++I N + +D +K +++N
Sbjct: 86 AHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFL 145
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ V T+ A+ ++ + N G+++ +SS+A + Y +K A+ F + I E
Sbjct: 146 SYVVLTVAALPMLKQSN----GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEY 201
Query: 544 HYAKSGVRVLSICFGATDT 600
++ V + G DT
Sbjct: 202 SVSRVNVSITLCVLGLIDT 220
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/199 (23%), Positives = 88/199 (44%), Gaps = 8/199 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVK 207
E +GK V++TGA+ GIG + + + G HV V S L+ ++
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGA-HVV---VTARSKETLQKVVSHCLELGAAS 85
Query: 208 FYKCDVTVEEL-FLELFDTVKNE-QGYLDVVINN------AAIMNDSYKSYKKQIDINVT 363
+ T+E++ F E F + G LD++I N + +D +K +++N
Sbjct: 86 AHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFL 145
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ V T+ A+ ++ + N G+++ +SS+A + Y +K A+ F + I E
Sbjct: 146 SYVVLTVAALPMLKQSN----GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEY 201
Query: 544 HYAKSGVRVLSICFGATDT 600
++ V + G DT
Sbjct: 202 SVSRVNVSITLCVLGLIDT 220
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/199 (23%), Positives = 88/199 (44%), Gaps = 8/199 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVK 207
E +GK V++TGA+ GIG + + + G HV V S L+ ++
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGA-HVV---VTARSKETLQKVVSHCLELGAAS 85
Query: 208 FYKCDVTVEEL-FLELFDTVKNE-QGYLDVVINN------AAIMNDSYKSYKKQIDINVT 363
+ T+E++ F E F + G LD++I N + +D +K +++N
Sbjct: 86 AHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFL 145
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ V T+ A+ ++ + N G+++ +SS+A + Y +K A+ F + I E
Sbjct: 146 SYVVLTVAALPMLKQSN----GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEY 201
Query: 544 HYAKSGVRVLSICFGATDT 600
++ V + G DT
Sbjct: 202 SVSRVNVSITLCVLGLIDT 220
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/199 (23%), Positives = 88/199 (44%), Gaps = 8/199 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVK 207
E +GK V++TGA+ GIG + + + G HV V S L+ ++
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGA-HVV---VTARSKETLQKVVSHCLELGAAS 85
Query: 208 FYKCDVTVEEL-FLELFDTVKNE-QGYLDVVINN------AAIMNDSYKSYKKQIDINVT 363
+ T+E++ F E F + G LD++I N + +D +K +++N
Sbjct: 86 AHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFL 145
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ V T+ A+ ++ + N G+++ +SS+A + Y +K A+ F + I E
Sbjct: 146 SYVVLTVAALPMLKQSN----GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEY 201
Query: 544 HYAKSGVRVLSICFGATDT 600
++ V + G DT
Sbjct: 202 SVSRVNVSITLCVLGLIDT 220
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 43.2 bits (97), Expect = 0.001
Identities = 47/199 (23%), Positives = 88/199 (44%), Gaps = 8/199 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVK 207
E +GK V++TGA+ GIG + + + G HV V S L+ ++
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGA-HVV---VTARSKETLQKVVSHCLELGAAS 85
Query: 208 FYKCDVTVEEL-FLELFDTVKNE-QGYLDVVINN------AAIMNDSYKSYKKQIDINVT 363
+ T+E++ F E F + G LD++I N + +D +K +++N
Sbjct: 86 AHYIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFL 145
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ V T+ A+ ++ + N G+++ +SS+A + Y +K A+ F + I E
Sbjct: 146 SYVVLTVAALPMLKQSN----GSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEY 201
Query: 544 HYAKSGVRVLSICFGATDT 600
++ V + G DT
Sbjct: 202 SVSRVNVSITLCVLGLIDT 220
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 357
+ DVT E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 358 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 453
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 357
+ DVT E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 358 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 453
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 357
+ DVT E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 358 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 453
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 357
+ DVT E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 358 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 453
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 357
+ DVT E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 358 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 453
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 357
+ DVT E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 358 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 453
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 357
+ DVT E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 358 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 453
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 357
+ DVT E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 358 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 453
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase
homolog isoform-1 protein.
Length = 279
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 357
+ DVT E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 358 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 453
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 42.3 bits (95), Expect = 0.002
Identities = 41/152 (26%), Positives = 69/152 (45%), Gaps = 9/152 (5%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
+E K + ITG SG G R ++G HV + E AL+ E + + +
Sbjct: 24 IEDITDKYIFITGCDSGFGNLAARTFDKKGF-HVIAACLTESGSTALKAETSER-----L 77
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYKKQIDIN 357
+ DVT E VKN+ G + +INNA + + + Y++ I++N
Sbjct: 78 RTVLLDVTDPENVKRTAQWVKNQVGEKGLWGLINNAGVPGVLAPTDWLTLEDYREPIEVN 137
Query: 358 VTALVTGTLKAIEIMGKQNGGKGGTVLNISSV 453
+ L++ TL + ++ K G V+N+SSV
Sbjct: 138 LFGLISVTLNMLPLVKKAQ----GRVINVSSV 165
>M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase
protein.
Length = 261
Score = 41.5 bits (93), Expect = 0.004
Identities = 69/259 (26%), Positives = 106/259 (40%), Gaps = 18/259 (6%)
Frame = +1
Query: 25 MESWKGKIV-LITGAASGIGEGVVRLILER-GVKHVAILDVAEDSG-RALENELNTKYGP 195
ME G+ V L+TGA+ G G + L+ V +L D R LE EL +
Sbjct: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60
Query: 196 NCVKFYKCDVTVEELFLELFDTVKN---EQGYLDVV-INNAAIMNDSYKSYKKQID---- 351
V D+ E +L ++ +G ++ INNA + D K + D
Sbjct: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120
Query: 352 -----INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQ 516
+N+T+++ T ++ + G TV+NISS+ AL + +Y K+A
Sbjct: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 517 FSNCIGLEEHYAKSGVRVLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNYPIQKM 696
+ LEE VRVL+ G DT + + S D ++ E K +
Sbjct: 180 LFQVLALEE----PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCK 235
Query: 697 ESAAK--GLVEAYEHAKSG 747
SA K L+E E KSG
Sbjct: 236 VSAQKLLSLLEKDEF-KSG 253
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 41.5 bits (93), Expect = 0.004
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 223 VTVEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 372
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYA 552
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 553 KSGVRVLSI 579
K G++V SI
Sbjct: 252 KWGIKVASI 260
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 41.5 bits (93), Expect = 0.004
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 223 VTVEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 372
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYA 552
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 553 KSGVRVLSI 579
K G++V SI
Sbjct: 252 KWGIKVASI 260
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 41.5 bits (93), Expect = 0.004
Identities = 36/142 (25%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALEN--ELNTKYGPNCVKFY 213
GK++++T AA GIG+ G K +A D+ E + LE + T+ + K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELEKYPGIQTRV-LDVTKKK 63
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAI 393
+ D E +E D + N G+ +++ +++ K + +++NV ++ +KA
Sbjct: 64 QIDQFASE--VERLDVLFNVAGF----VHHGTVLDCEEKDWDFSMNLNVRSMYL-MIKA- 115
Query: 394 EIMGKQNGGKGGTVLNISSVAA 459
+ K K G ++N+SSVA+
Sbjct: 116 -FLPKMLAQKSGNIINMSSVAS 136
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 41.5 bits (93), Expect = 0.004
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 223 VTVEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 372
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYA 552
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 553 KSGVRVLSI 579
K G++V SI
Sbjct: 252 KWGIKVASI 260
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 41.5 bits (93), Expect = 0.004
Identities = 36/142 (25%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALEN--ELNTKYGPNCVKFY 213
GK++++T AA GIG+ G K +A D+ E + LE + T+ + K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELEKYPGIQTRV-LDVTKKK 63
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAI 393
+ D E +E D + N G+ +++ +++ K + +++NV ++ +KA
Sbjct: 64 QIDQFANE--VERLDVLFNVAGF----VHHGTVLDCEEKDWDFSMNLNVRSMYL-MIKA- 115
Query: 394 EIMGKQNGGKGGTVLNISSVAA 459
+ K K G ++N+SSVA+
Sbjct: 116 -FLPKMLAQKSGNIINMSSVAS 136
>BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) protein.
Length = 261
Score = 41.5 bits (93), Expect = 0.004
Identities = 69/259 (26%), Positives = 106/259 (40%), Gaps = 18/259 (6%)
Frame = +1
Query: 25 MESWKGKIV-LITGAASGIGEGVVRLILER-GVKHVAILDVAEDSG-RALENELNTKYGP 195
ME G+ V L+TGA+ G G + L+ V +L D R LE EL +
Sbjct: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60
Query: 196 NCVKFYKCDVTVEELFLELFDTVKN---EQGYLDVV-INNAAIMNDSYKSYKKQID---- 351
V D+ E +L ++ +G ++ INNA + D K + D
Sbjct: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120
Query: 352 -----INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQ 516
+N+T+++ T ++ + G TV+NISS+ AL + +Y K+A
Sbjct: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 517 FSNCIGLEEHYAKSGVRVLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNYPIQKM 696
+ LEE VRVL+ G DT + + S D ++ E K +
Sbjct: 180 LFQVLALEE----PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCK 235
Query: 697 ESAAK--GLVEAYEHAKSG 747
SA K L+E E KSG
Sbjct: 236 VSAQKLLSLLEKDEF-KSG 253
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 41.5 bits (93), Expect = 0.004
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 223 VTVEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 372
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYA 552
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 553 KSGVRVLSI 579
K G++V SI
Sbjct: 252 KWGIKVASI 260
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 41.5 bits (93), Expect = 0.004
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 223 VTVEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 372
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYA 552
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 553 KSGVRVLSI 579
K G++V SI
Sbjct: 252 KWGIKVASI 260
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 41.5 bits (93), Expect = 0.004
Identities = 49/189 (25%), Positives = 82/189 (43%), Gaps = 10/189 (5%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
K VL+TG G+G + + + E G V ++G E EL P + + D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELG--FTVFAGVLNENGPGAE-ELRRTCSPR-LSVLQMD 138
Query: 223 VTVEELFLELFDTVK---NEQGYLDVVINNAAIM---NDS----YKSYKKQIDINVTALV 372
+T + + V ++G L VINNA ++ D YK+ + +N V
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRG-LWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTV 197
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYA 552
T + ++ K G ++N+SS+ Y +K+AV FS+ + LE +
Sbjct: 198 EVTKTFLPLLRKSK----GRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLE--LS 251
Query: 553 KSGVRVLSI 579
K G++V SI
Sbjct: 252 KWGIKVASI 260
>AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) variant
protein.
Length = 261
Score = 41.5 bits (93), Expect = 0.004
Identities = 69/259 (26%), Positives = 106/259 (40%), Gaps = 18/259 (6%)
Frame = +1
Query: 25 MESWKGKIV-LITGAASGIGEGVVRLILER-GVKHVAILDVAEDSG-RALENELNTKYGP 195
ME G+ V L+TGA+ G G + L+ V +L D R LE EL +
Sbjct: 1 MEGGLGRAVRLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60
Query: 196 NCVKFYKCDVTVEELFLELFDTVKN---EQGYLDVV-INNAAIMNDSYKSYKKQID---- 351
V D+ E +L ++ +G ++ INNA + D K + D
Sbjct: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120
Query: 352 -----INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQ 516
+N+T+++ T ++ + G TV+NISS+ AL + +Y K+A
Sbjct: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 517 FSNCIGLEEHYAKSGVRVLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNYPIQKM 696
+ LEE VRVL+ G DT + + S D ++ E K +
Sbjct: 180 LFQVLALEE----PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCK 235
Query: 697 ESAAK--GLVEAYEHAKSG 747
SA K L+E E KSG
Sbjct: 236 VSAQKLLSLLEKDEF-KSG 253
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 41.5 bits (93), Expect = 0.004
Identities = 36/142 (25%), Positives = 69/142 (48%), Gaps = 2/142 (1%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALEN--ELNTKYGPNCVKFY 213
GK++++T AA GIG+ G K +A D+ E + LE + T+ + K
Sbjct: 6 GKVIILTAAAQGIGQAAALAFAREGAKVIA-TDINESKLQELEKYPGIQTRV-LDVTKKK 63
Query: 214 KCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTGTLKAI 393
+ D E +E D + N G+ +++ +++ K + +++NV ++ +KA
Sbjct: 64 QIDQFANE--VERLDVLFNVAGF----VHHGTVLDCEEKDWDFSMNLNVRSMYL-MIKA- 115
Query: 394 EIMGKQNGGKGGTVLNISSVAA 459
+ K K G ++N+SSVA+
Sbjct: 116 -FLPKMLAQKSGNIINMSSVAS 136
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 41.1 bits (92), Expect = 0.005
Identities = 52/219 (23%), Positives = 89/219 (40%), Gaps = 9/219 (4%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAI---LDVAEDSGRALENELNTKYGPNCVK 207
+ +V+ITGA SG+G+ ++ G K V E+ R L TK +
Sbjct: 56 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 115
Query: 208 FYKCDVTVEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTAL 369
D+T + + GY+D+++NNA IM+ + K+ ++ N
Sbjct: 116 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 175
Query: 370 VTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
V T + M K+ + G ++ ISS+ Y +K A F +C+ E
Sbjct: 176 VALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 232
Query: 550 AKSGVRVLSICFGATDTPLLNGTKLGSFDEEIDGTCVEA 666
+ V V+S + T+ + T GS +D T +A
Sbjct: 233 YEIEVTVISPGYIHTNLSVNAITADGSRYGVMDTTTAQA 271
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 40.7 bits (91), Expect = 0.006
Identities = 49/194 (25%), Positives = 83/194 (42%), Gaps = 9/194 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNC 201
+S G+IVLITGA GIG R K +IL + + + R +E K G
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVT- 86
Query: 202 VKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 363
Y D + E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE- 540
T + M ++N G TV ++ + +L P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 541 EHYAKSGVRVLSIC 582
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 40.7 bits (91), Expect = 0.006
Identities = 49/194 (25%), Positives = 83/194 (42%), Gaps = 9/194 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNC 201
+S G+IVLITGA GIG R K +IL + + + R +E K G
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVT- 86
Query: 202 VKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 363
Y D + E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE- 540
T + M ++N G TV ++ + +L P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 541 EHYAKSGVRVLSIC 582
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 40.7 bits (91), Expect = 0.006
Identities = 49/194 (25%), Positives = 83/194 (42%), Gaps = 9/194 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNC 201
+S G+IVLITGA GIG R K +IL + + + R +E K G
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVT- 86
Query: 202 VKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 363
Y D + E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE- 540
T + M ++N G TV ++ + +L P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 541 EHYAKSGVRVLSIC 582
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 40.7 bits (91), Expect = 0.006
Identities = 49/194 (25%), Positives = 83/194 (42%), Gaps = 9/194 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNC 201
+S G+IVLITGA GIG R K +IL + + + R +E K G
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVT- 86
Query: 202 VKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 363
Y D + E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE- 540
T + M ++N G TV ++ + +L P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 541 EHYAKSGVRVLSIC 582
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 40.7 bits (91), Expect = 0.006
Identities = 49/194 (25%), Positives = 83/194 (42%), Gaps = 9/194 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNC 201
+S G+IVLITGA GIG R K +IL + + + R +E K G
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVT- 86
Query: 202 VKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 363
Y D + E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE- 540
T + M ++N G TV ++ + +L P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 541 EHYAKSGVRVLSIC 582
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 40.7 bits (91), Expect = 0.006
Identities = 49/194 (25%), Positives = 83/194 (42%), Gaps = 9/194 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELN--TKYGPNC 201
+S G+IVLITGA GIG R K +IL + + + R +E K G
Sbjct: 32 KSVAGEIVLITGAGHGIG----RQTTYEFAKRQSILVLWDINKRGVEETAAECRKLGVT- 86
Query: 202 VKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVT 363
Y D + E + VK E G + +V+NNA +++ + K ++N+
Sbjct: 87 AHAYVVDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNIL 146
Query: 364 ALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE- 540
T + M ++N G TV ++ + +L P Y +K A + F + E
Sbjct: 147 GHFWITKALLPSMMERNHGHIVTVASVCGHEGI--PYLIP-YCSSKFAAVGFHRGLTSEL 203
Query: 541 EHYAKSGVRVLSIC 582
+ K+G++ +C
Sbjct: 204 QALGKTGIKTSCLC 217
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 40.3 bits (90), Expect = 0.008
Identities = 45/189 (23%), Positives = 77/189 (40%), Gaps = 9/189 (4%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAI---LDVAEDSGRALENELNTKYGPNCVK 207
+ +V+ITGA SG+G+ ++ G K V E+ R L TK +
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query: 208 FYKCDVTVEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTAL 369
D+T + + GY+D+++NNA IM+ + K+ ++ N
Sbjct: 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query: 370 VTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
V T + M K+ + G ++ ISS+ Y +K A F +C+ E
Sbjct: 171 VALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 227
Query: 550 AKSGVRVLS 576
+ V V+S
Sbjct: 228 YEIEVTVIS 236
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 40.3 bits (90), Expect = 0.008
Identities = 45/189 (23%), Positives = 77/189 (40%), Gaps = 9/189 (4%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAI---LDVAEDSGRALENELNTKYGPNCVK 207
+ +V+ITGA SG+G+ ++ G K V E+ R L TK +
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query: 208 FYKCDVTVEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTAL 369
D+T + + GY+D+++NNA IM+ + K+ ++ N
Sbjct: 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query: 370 VTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
V T + M K+ + G ++ ISS+ Y +K A F +C+ E
Sbjct: 171 VALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 227
Query: 550 AKSGVRVLS 576
+ V V+S
Sbjct: 228 YEIEVTVIS 236
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 40.3 bits (90), Expect = 0.008
Identities = 45/189 (23%), Positives = 77/189 (40%), Gaps = 9/189 (4%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAI---LDVAEDSGRALENELNTKYGPNCVK 207
+ +V+ITGA SG+G+ ++ G K V E+ R L TK +
Sbjct: 51 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 110
Query: 208 FYKCDVTVEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTAL 369
D+T + + GY+D+++NNA IM+ + K+ ++ N
Sbjct: 111 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 170
Query: 370 VTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
V T + M K+ + G ++ ISS+ Y +K A F +C+ E
Sbjct: 171 VALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 227
Query: 550 AKSGVRVLS 576
+ V V+S
Sbjct: 228 YEIEVTVIS 236
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 40.3 bits (90), Expect = 0.008
Identities = 45/189 (23%), Positives = 77/189 (40%), Gaps = 9/189 (4%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAI---LDVAEDSGRALENELNTKYGPNCVK 207
+ +V+ITGA SG+G+ ++ G K V E+ R L TK +
Sbjct: 36 RNAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPY 95
Query: 208 FYKCDVTVEELFLELFDTVKNEQGYLDVVINNA------AIMNDSYKSYKKQIDINVTAL 369
D+T + + GY+D+++NNA IM+ + K+ ++ N
Sbjct: 96 LVTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGP 155
Query: 370 VTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHY 549
V T + M K+ + G ++ ISS+ Y +K A F +C+ E
Sbjct: 156 VALTKALLPSMIKR---RQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQ 212
Query: 550 AKSGVRVLS 576
+ V V+S
Sbjct: 213 YEIEVTVIS 221
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 40.3 bits (90), Expect = 0.008
Identities = 29/81 (35%), Positives = 42/81 (51%)
Frame = +1
Query: 337 KKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQ 516
KK I+IN+ ++ T + M +++ G +LNISS + + L IY TK+ V
Sbjct: 20 KKMININILSVCKMTQLVLPGMVERSKG---AILNISSGSGMLPVPLLTIYSATKTFVDF 76
Query: 517 FSNCIGLEEHYAKSGVRVLSI 579
FS C L E Y GV V S+
Sbjct: 77 FSQC--LHEEYRSKGVFVQSV 95
>DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein.
Length = 118
Score = 39.1 bits (87), Expect = 0.019
Identities = 25/78 (32%), Positives = 44/78 (56%)
Frame = +1
Query: 307 AIMNDSYKSYKKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPI 486
++M+ + + + K +DINV A T + M K+ GG+V+ +SS+AA S F
Sbjct: 1 SLMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSP 57
Query: 487 YFGTKSAVLQFSNCIGLE 540
Y +K+A+L +N + +E
Sbjct: 58 YNVSKTALLGLNNTLAIE 75
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 39.1 bits (87), Expect = 0.019
Identities = 58/247 (23%), Positives = 106/247 (42%), Gaps = 10/247 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC--VKFYK 216
K VL+TG SG G + + + +G A + +D G EL++ V+
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGC-LMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 217 CDVTVEELFLELF-DTVKNEQGYLDVVINNAAIMN------DSYKSYKKQIDINVTALVT 375
C E +E+ ++K+ + + ++NNA I S ++YK+ ++N+ V
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 376 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
T + ++ + G V+NISS+ + Y TK V FS+C+ E +
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLG 230
Query: 556 SGVRVLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNYPIQKM-ESAAKGLVEAYE 732
V V+ T L + + + +++ E ++K+Y + E AK +E Y
Sbjct: 231 VKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAK--METYC 288
Query: 733 HAKSGDT 753
+ S DT
Sbjct: 289 SSGSTDT 295
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 39.1 bits (87), Expect = 0.019
Identities = 58/247 (23%), Positives = 106/247 (42%), Gaps = 10/247 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC--VKFYK 216
K VL+TG SG G + + + +G A + +D G EL++ V+
Sbjct: 56 KAVLVTGCDSGFGFALAKHLHSKGFLVFAGC-LMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 217 CDVTVEELFLELF-DTVKNEQGYLDVVINNAAIMN------DSYKSYKKQIDINVTALVT 375
C E +E+ ++K+ + + ++NNA I S ++YK+ ++N+ V
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 376 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
T + ++ + G V+NISS+ + Y TK V FS+C+ E +
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLG 230
Query: 556 SGVRVLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNYPIQKM-ESAAKGLVEAYE 732
V V+ T L + + + +++ E ++K+Y + E AK +E Y
Sbjct: 231 VKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAK--METYC 288
Query: 733 HAKSGDT 753
+ S DT
Sbjct: 289 SSGSTDT 295
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 39.1 bits (87), Expect = 0.019
Identities = 58/247 (23%), Positives = 106/247 (42%), Gaps = 10/247 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC--VKFYK 216
K VL+TG SG G + + + +G A + +D G EL++ V+
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGC-LMKDKGHDGVKELDSLNSDRLRTVQLNV 114
Query: 217 CDVTVEELFLELF-DTVKNEQGYLDVVINNAAIMN------DSYKSYKKQIDINVTALVT 375
C E +E+ ++K+ + + ++NNA I S ++YK+ ++N+ V
Sbjct: 115 CSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVNLWGTVR 174
Query: 376 GTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAK 555
T + ++ + G V+NISS+ + Y TK V FS+C+ E +
Sbjct: 175 MTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPLG 230
Query: 556 SGVRVLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNYPIQKM-ESAAKGLVEAYE 732
V V+ T L + + + +++ E ++K+Y + E AK +E Y
Sbjct: 231 VKVSVVEPGNFIAATSLYSPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAK--METYC 288
Query: 733 HAKSGDT 753
+ S DT
Sbjct: 289 SSGSTDT 295
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 39.1 bits (87), Expect = 0.019
Identities = 41/191 (21%), Positives = 86/191 (45%), Gaps = 7/191 (3%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN---CVK 207
+G++ ++TG A+GIG+ +V+ +LE G +V I + ++ +EL P V
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 208 FYKCDVTVEELFLELFDTVKNEQGYLDVVINNAA--IMNDSYKSYKKQIDINVTALVTGT 381
+C++ EE L + + G ++ ++NN ++ + K + +TGT
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135
Query: 382 LKAIE-IMGKQNGGKGGTVLNISSVAALCQSHLFPIYFG-TKSAVLQFSNCIGLEEHYAK 555
+ + GG+++NI + ++ G ++ V + + LE +A
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALE--WAC 191
Query: 556 SGVRVLSICFG 588
SG+R+ + G
Sbjct: 192 SGIRINCVAPG 202
>AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein.
Length = 377
Score = 39.1 bits (87), Expect = 0.019
Identities = 26/96 (27%), Positives = 46/96 (47%)
Frame = +1
Query: 25 MESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCV 204
M + +G+ ++TGA SGIG+ + RG + V + +++ G A +L + G N V
Sbjct: 31 MGNLRGRTAVVTGANSGIGKMTALELARRGAR-VVLACRSQERGEAAAFDLRQESGNNEV 89
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAI 312
F D+ + + LD++I+NA I
Sbjct: 90 IFMALDLASLASVRAFATAFLSSEPRLDILIHNAGI 125
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 39.1 bits (87), Expect = 0.019
Identities = 41/191 (21%), Positives = 86/191 (45%), Gaps = 7/191 (3%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN---CVK 207
+G++ ++TG A+GIG+ +V+ +LE G +V I + ++ +EL P V
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 208 FYKCDVTVEELFLELFDTVKNEQGYLDVVINNAA--IMNDSYKSYKKQIDINVTALVTGT 381
+C++ EE L + + G ++ ++NN ++ + K + +TGT
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135
Query: 382 LKAIE-IMGKQNGGKGGTVLNISSVAALCQSHLFPIYFG-TKSAVLQFSNCIGLEEHYAK 555
+ + GG+++NI + ++ G ++ V + + LE +A
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALE--WAC 191
Query: 556 SGVRVLSICFG 588
SG+R+ + G
Sbjct: 192 SGIRINCVAPG 202
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 39.1 bits (87), Expect = 0.019
Identities = 41/191 (21%), Positives = 86/191 (45%), Gaps = 7/191 (3%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN---CVK 207
+G++ ++TG A+GIG+ +V+ +LE G +V I + ++ +EL P V
Sbjct: 36 QGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQARVI 94
Query: 208 FYKCDVTVEELFLELFDTVKNEQGYLDVVINNAA--IMNDSYKSYKKQIDINVTALVTGT 381
+C++ EE L + + G ++ ++NN ++ + K + +TGT
Sbjct: 95 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 154
Query: 382 LKAIE-IMGKQNGGKGGTVLNISSVAALCQSHLFPIYFG-TKSAVLQFSNCIGLEEHYAK 555
+ + GG+++NI + ++ G ++ V + + LE +A
Sbjct: 155 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALE--WAC 210
Query: 556 SGVRVLSICFG 588
SG+R+ + G
Sbjct: 211 SGIRINCVAPG 221
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 39.1 bits (87), Expect = 0.019
Identities = 41/191 (21%), Positives = 86/191 (45%), Gaps = 7/191 (3%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN---CVK 207
+G++ ++TG A+GIG+ +V+ +LE G +V I + ++ +EL P V
Sbjct: 17 QGQVAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 208 FYKCDVTVEELFLELFDTVKNEQGYLDVVINNAA--IMNDSYKSYKKQIDINVTALVTGT 381
+C++ EE L + + G ++ ++NN ++ + K + +TGT
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLETNLTGT 135
Query: 382 LKAIE-IMGKQNGGKGGTVLNISSVAALCQSHLFPIYFG-TKSAVLQFSNCIGLEEHYAK 555
+ + GG+++NI + ++ G ++ V + + LE +A
Sbjct: 136 FYMCKAVYSSWMKEHGGSIVNI--IVPTKAGFPLAVHSGAARAGVYNLTKSLALE--WAC 191
Query: 556 SGVRVLSICFG 588
SG+R+ + G
Sbjct: 192 SGIRINCVAPG 202
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 38.7 bits (86), Expect = 0.025
Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 10/210 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-V 204
+S G+IVLITGA GIG RL K + L + + + LE G V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 366
+ D + E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEH 546
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 547 YAK-SGVRVLSICFGATDTPLLN--GTKLG 627
+ +GV+ +C +T + T LG
Sbjct: 205 ALQITGVKTTCLCPNFVNTGFIKNPSTSLG 234
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 38.7 bits (86), Expect = 0.025
Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 10/210 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-V 204
+S G+IVLITGA GIG RL K + L + + + LE G V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 366
+ D + E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEH 546
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 547 YAK-SGVRVLSICFGATDTPLLN--GTKLG 627
+ +GV+ +C +T + T LG
Sbjct: 205 ALQITGVKTTCLCPNFVNTGFIKNPSTSLG 234
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 38.7 bits (86), Expect = 0.025
Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 10/210 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-V 204
+S G+IVLITGA GIG RL K + L + + + LE G V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 366
+ D + E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEH 546
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 547 YAK-SGVRVLSICFGATDTPLLN--GTKLG 627
+ +GV+ +C +T + T LG
Sbjct: 205 ALQITGVKTTCLCPNFVNTGFIKNPSTSLG 234
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 38.7 bits (86), Expect = 0.025
Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 10/210 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-V 204
+S G+IVLITGA GIG RL K + L + + + LE G V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 366
+ D + E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEH 546
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 547 YAK-SGVRVLSICFGATDTPLLN--GTKLG 627
+ +GV+ +C +T + T LG
Sbjct: 205 ALQITGVKTTCLCPNFVNTGFIKNPSTSLG 234
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 38.7 bits (86), Expect = 0.025
Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 10/210 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-V 204
+S G+IVLITGA GIG RL K + L + + + LE G V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 366
+ D + E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEH 546
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 547 YAK-SGVRVLSICFGATDTPLLN--GTKLG 627
+ +GV+ +C +T + T LG
Sbjct: 205 ALQITGVKTTCLCPNFVNTGFIKNPSTSLG 234
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 38.7 bits (86), Expect = 0.025
Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 10/210 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-V 204
+S G+IVLITGA GIG RL K + L + + + LE G V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 366
+ D + E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEH 546
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 547 YAK-SGVRVLSICFGATDTPLLN--GTKLG 627
+ +GV+ +C +T + T LG
Sbjct: 205 ALQITGVKTTCLCPNFVNTGFIKNPSTSLG 234
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 38.7 bits (86), Expect = 0.025
Identities = 54/210 (25%), Positives = 87/210 (41%), Gaps = 10/210 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-V 204
+S G+IVLITGA GIG RL K + L + + + LE G V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 366
+ D + E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEH 546
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 547 YAK-SGVRVLSICFGATDTPLLN--GTKLG 627
+ +GV+ +C +T + T LG
Sbjct: 205 ALQITGVKTTCLCPNFVNTGFIKNPSTSLG 234
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 38.3 bits (85), Expect = 0.033
Identities = 59/248 (23%), Positives = 108/248 (43%), Gaps = 11/248 (4%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVA---ILDVAEDSGRALENELNTKYGPNCVKFY 213
K VL+TG SG G + + + +G A + D D + L++ + + + +
Sbjct: 56 KAVLVTGCDSGFGFSLAKHLHSKGFLVFAGCLMKDKGHDGVKELDSLNSDRLRTVQLNVF 115
Query: 214 KCDVTVEELFLEL-FDTVKNEQGYLDVVINNAAIMN------DSYKSYKKQIDINVTALV 372
+ + VE++ + F+ E+G +V NNA I S ++YK+ ++N+ V
Sbjct: 116 RSE-EVEKVVGDCPFEPEGPEKGMWGLV-NNAGISTFGEVEFTSLETYKQVAEVNLWGTV 173
Query: 373 TGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYA 552
T + ++ + G V+NISS+ + Y TK V FS+C+ E +
Sbjct: 174 RMTKSFLPLIRRAKG----RVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYPL 229
Query: 553 KSGVRVLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNYPIQKM-ESAAKGLVEAY 729
V V+ T L N + + +++ E ++K+Y + E AK +E Y
Sbjct: 230 GVKVSVVEPGNFIAATSLYNPESIQAIAKKMWEELPEVVRKDYGKKYFDEKIAK--METY 287
Query: 730 EHAKSGDT 753
+ S DT
Sbjct: 288 CSSGSTDT 295
>EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/90 (27%), Positives = 47/90 (52%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ L+TGA GIG + R + + V + G+A +L + G + +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLS-PRFHQLD 63
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/90 (27%), Positives = 47/90 (52%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ L+TGA GIG + R + + V + G+A +L + G + +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLS-PRFHQLD 63
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/90 (27%), Positives = 47/90 (52%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ L+TGA GIG + R + + V + G+A +L + G + +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLS-PRFHQLD 63
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NADPH)
3, EC 1.1.1.284. protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/90 (27%), Positives = 47/90 (52%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ L+TGA GIG + R + + V + G+A +L + G + +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLS-PRFHQLD 63
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/90 (27%), Positives = 47/90 (52%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ L+TGA GIG + R + + V + G+A +L + G + +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLS-PRFHQLD 63
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3
variant protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/90 (27%), Positives = 47/90 (52%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ L+TGA GIG + R + + V + G+A +L + G + +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLS-PRFHQLD 63
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/90 (27%), Positives = 47/90 (52%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ L+TGA GIG + R + + V + G+A +L + G + +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLS-PRFHQLD 63
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbonyl
reductase 3 protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/90 (27%), Positives = 47/90 (52%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ L+TGA GIG + R + + V + G+A +L + G + +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLS-PRFHQLD 63
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/90 (27%), Positives = 47/90 (52%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ L+TGA GIG + R + + V + G+A +L + G + +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLS-PRFHQLD 63
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3
protein.
Length = 277
Score = 37.9 bits (84), Expect = 0.043
Identities = 25/90 (27%), Positives = 47/90 (52%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ L+TGA GIG + R + + V + G+A +L + G + +F++ D
Sbjct: 6 RVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE-GLS-PRFHQLD 63
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ + L D ++ E G L+V++NNAA+
Sbjct: 64 IDDLQSIRALRDFLRKEYGGLNVLVNNAAV 93
>BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein.
Length = 312
Score = 37.5 bits (83), Expect = 0.057
Identities = 39/159 (24%), Positives = 69/159 (43%), Gaps = 5/159 (3%)
Frame = +1
Query: 7 YVEHCVMESWKGKIVLITGAASGIGEGVVRLILER-GVKHVAILDVAEDSGRALENELNT 183
+V H + G++ L+TG SGIG+ I +R G H+ D A E+
Sbjct: 24 FVPHDLEVQIPGRVFLVTGGNSGIGKATALEIAKRGGTVHLVCRDQA--PAEDARGEIIR 81
Query: 184 KYGPNCVKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVT 363
+ G + + D++ + + + K E L V+INNA M + + + ++ N
Sbjct: 82 ESGNQNIFLHIVDLSDPKQIWKFVENFKQEH-KLHVLINNAGCMVNKRELTEDGLEKNFA 140
Query: 364 ALVTG----TLKAIEIMGKQNGGKGGTVLNISSVAALCQ 468
A G T I ++ K++ + V+ +SS L Q
Sbjct: 141 ANTLGVYILTTGLIPVLEKEHDPR---VITVSSGGMLVQ 176
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 37.1 bits (82), Expect = 0.075
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 13/180 (7%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAED-----SGRALENELNTKYGPNCV 204
G++VL+TGA +G+G ERG V + D+ D G +++ +
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGAL-VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGG 67
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID--------INV 360
K +VEE ++ T + G +DVV+NNA I+ D +S+ + D +++
Sbjct: 68 KAVANYDSVEE-GEKVVKTALDAFGRIDVVVNNAGILRD--RSFARISDEDWDIIHRVHL 124
Query: 361 TALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
T A E M KQ K G ++ SS + + + Y K +L +N + +E
Sbjct: 125 RGSFQVTRAAWEHMKKQ---KYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
>M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 37.1 bits (82), Expect = 0.075
Identities = 52/203 (25%), Positives = 95/203 (46%), Gaps = 7/203 (3%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
K V ITG SG G + + +++RG++ +A E+ + L+ + + + + K +
Sbjct: 26 KYVFITGCDSGFGNLLAKQLVDRGMQVLAAC-FTEEGSQKLQRDTSYRLQTTLLDVTKSE 84
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI-----MND--SYKSYKKQIDINVTALVTGT 381
+++ + D V EQG L ++NNA + N+ + + K I++N+ L+ T
Sbjct: 85 -SIKAAAQWVRDKV-GEQG-LWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVT 141
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSG 561
L + ++ + G V+N+SS + + Y +K V FS+ I E +Y G
Sbjct: 142 LHMLPMVKRAR----GRVVNMSSSGGRV-AVIGGGYCVSKFGVEAFSDSIRRELYY--FG 194
Query: 562 VRVLSICFGATDTPLLNGTKLGS 630
V+V I G T +L L S
Sbjct: 195 VKVCIIEPGNYRTAILGKENLES 217
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 37.1 bits (82), Expect = 0.075
Identities = 52/203 (25%), Positives = 95/203 (46%), Gaps = 7/203 (3%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
K V ITG SG G + + +++RG++ +A E+ + L+ + + + + K +
Sbjct: 26 KYVFITGCDSGFGNLLAKQLVDRGMQVLAAC-FTEEGSQKLQRDTSYRLQTTLLDVTKSE 84
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI-----MND--SYKSYKKQIDINVTALVTGT 381
+++ + D V EQG L ++NNA + N+ + + K I++N+ L+ T
Sbjct: 85 -SIKAAAQWVRDKV-GEQG-LWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVT 141
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSG 561
L + ++ + G V+N+SS + + Y +K V FS+ I E +Y G
Sbjct: 142 LHMLPMVKRAR----GRVVNMSSSGGRV-AVIGGGYCVSKFGVEAFSDSIRRELYY--FG 194
Query: 562 VRVLSICFGATDTPLLNGTKLGS 630
V+V I G T +L L S
Sbjct: 195 VKVCIIEPGNYRTAILGKENLES 217
>BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 37.1 bits (82), Expect = 0.075
Identities = 53/210 (25%), Positives = 86/210 (40%), Gaps = 10/210 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-V 204
+S G+IVLITGA GIG RL K + L + + + LE G V
Sbjct: 32 KSVTGEIVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 366
+ D + E K E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKNCKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEH 546
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 547 YAK-SGVRVLSICFGATDTPLLN--GTKLG 627
+ +GV+ +C +T + T LG
Sbjct: 205 ALQITGVKTTCLCPNFVNTGFIKKMSTSLG 234
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 37.1 bits (82), Expect = 0.075
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 13/180 (7%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAED-----SGRALENELNTKYGPNCV 204
G++VL+TGA +G+G ERG V + D+ D G +++ +
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGAL-VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGG 67
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID--------INV 360
K +VEE ++ T + G +DVV+NNA I+ D +S+ + D +++
Sbjct: 68 KAVANYDSVEE-GEKVVKTALDAFGRIDVVVNNAGILRD--RSFARISDEDWDIIHRVHL 124
Query: 361 TALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
T A E M KQ K G ++ SS + + + Y K +L +N + +E
Sbjct: 125 RGSFQVTRAAWEHMKKQ---KYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
>BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 37.1 bits (82), Expect = 0.075
Identities = 52/203 (25%), Positives = 95/203 (46%), Gaps = 7/203 (3%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
K V ITG SG G + + +++RG++ +A E+ + L+ + + + + K +
Sbjct: 26 KYVFITGCDSGFGNLLAKQLVDRGMQVLAAC-FTEEGSQKLQRDTSYRLQTTLLDVTKSE 84
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAI-----MND--SYKSYKKQIDINVTALVTGT 381
+++ + D V EQG L ++NNA + N+ + + K I++N+ L+ T
Sbjct: 85 -SIKAAAQWVRDKV-GEQG-LWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIEVT 141
Query: 382 LKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSG 561
L + ++ + G V+N+SS + + Y +K V FS+ I E +Y G
Sbjct: 142 LHMLPMVKRAR----GRVVNMSSSGGRV-AVIGGGYCVSKFGVEAFSDSIRRELYY--FG 194
Query: 562 VRVLSICFGATDTPLLNGTKLGS 630
V+V I G T +L L S
Sbjct: 195 VKVCIIEPGNYRTAILGKENLES 217
>AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase
(NAPDH)1, EC 1.1.1.184 protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 37.1 bits (82), Expect = 0.075
Identities = 46/180 (25%), Positives = 79/180 (43%), Gaps = 13/180 (7%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAED-----SGRALENELNTKYGPNCV 204
G++VL+TGA +G+G ERG V + D+ D G +++ +
Sbjct: 9 GRVVLVTGAGAGLGRAYALAFAERGAL-VVVNDLGGDFKGVGKGSLAADKVVEEIRRRGG 67
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID--------INV 360
K +VEE ++ T + G +DVV+NNA I+ D +S+ + D +++
Sbjct: 68 KAVANYDSVEE-GEKVVKTALDAFGRIDVVVNNAGILRD--RSFARISDEDWDIIHRVHL 124
Query: 361 TALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLE 540
T A E M KQ K G ++ SS + + + Y K +L +N + +E
Sbjct: 125 RGSFQVTRAAWEHMKKQ---KYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIE 181
>AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase
protein.
Length = 277
Score = 37.1 bits (82), Expect = 0.075
Identities = 26/89 (29%), Positives = 44/89 (49%)
Frame = +1
Query: 46 IVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDV 225
+ L+TG GIG +VR + V + G+A +L + G + +F++ D+
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAE-GLS-PRFHQLDI 64
Query: 226 TVEELFLELFDTVKNEQGYLDVVINNAAI 312
+ L D ++ E G LDV++NNA I
Sbjct: 65 DDLQSIRALRDFLRKEYGGLDVLVNNAGI 93
>CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 36.7 bits (81), Expect = 0.100
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 121 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 179
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
+ + K ++ L V+INNA +M
Sbjct: 180 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 210
>CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 36.7 bits (81), Expect = 0.100
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 36.7 bits (81), Expect = 0.100
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 121 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 179
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
+ + K ++ L V+INNA +M
Sbjct: 180 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 210
>BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 36.7 bits (81), Expect = 0.100
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 330
Score = 36.7 bits (81), Expect = 0.100
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein.
Length = 330
Score = 36.7 bits (81), Expect = 0.100
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 36.7 bits (81), Expect = 0.100
Identities = 44/192 (22%), Positives = 79/192 (41%), Gaps = 8/192 (4%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+ K+ ITG SGIG + + + G H I + +L G C+
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHGC-HTVIASRSLPRVLTAARKLAGATGRRCLPL-S 84
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVTALVTG 378
DV + D E G +D++IN AA S+ ++K +DI+ +G
Sbjct: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID----TSG 140
Query: 379 TLKAIEIM-GKQNGGKGGTVLNISSVAALCQSHLFPIYFGT-KSAVLQFSNCIGLEEHYA 552
T ++ K GG ++NI++ + ++ G+ K+AV + + +E +
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLG-NRGQALQVHAGSAKAAVDAMTRHLAVE--WG 197
Query: 553 KSGVRVLSICFG 588
+RV S+ G
Sbjct: 198 PQNIRVNSLAPG 209
>AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein.
Length = 330
Score = 36.7 bits (81), Expect = 0.100
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 36.7 bits (81), Expect = 0.100
Identities = 44/192 (22%), Positives = 79/192 (41%), Gaps = 8/192 (4%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+ K+ ITG SGIG + + + G H I + +L G C+
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHGC-HTVIASRSLPRVLTAARKLAGATGRRCLPL-S 84
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVTALVTG 378
DV + D E G +D++IN AA S+ ++K +DI+ +G
Sbjct: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID----TSG 140
Query: 379 TLKAIEIM-GKQNGGKGGTVLNISSVAALCQSHLFPIYFGT-KSAVLQFSNCIGLEEHYA 552
T ++ K GG ++NI++ + ++ G+ K+AV + + +E +
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLG-NRGQALQVHAGSAKAAVDAMTRHLAVE--WG 197
Query: 553 KSGVRVLSICFG 588
+RV S+ G
Sbjct: 198 PQNIRVNSLAPG 209
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 36.7 bits (81), Expect = 0.100
Identities = 53/210 (25%), Positives = 86/210 (40%), Gaps = 10/210 (4%)
Frame = +1
Query: 28 ESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNC-V 204
+S G+ VLITGA GIG RL K + L + + + LE G V
Sbjct: 32 KSVTGETVLITGAGHGIG----RLTAYEFAKLKSKLVLWDINKHGLEETAAKCKGLGAKV 87
Query: 205 KFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIM--NDSYKSYKKQI----DINVTA 366
+ D + E VK E G + +++NNA ++ +D + + QI ++NV A
Sbjct: 88 HTFVVDCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQIEKTFEVNVLA 147
Query: 367 LVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEH 546
T + M K N G ++ ++S A Y +K A + F + E
Sbjct: 148 HFWTTKAFLPAMTKNNHGH---IVTVASAAGHVSVPFLLAYCSSKFAAVGFHKTLTDELA 204
Query: 547 YAK-SGVRVLSICFGATDTPLLN--GTKLG 627
+ +GV+ +C +T + T LG
Sbjct: 205 ALQITGVKTTCLCPNFVNTGFIKNPSTSLG 234
>AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase
protein.
Length = 330
Score = 36.7 bits (81), Expect = 0.100
Identities = 21/91 (23%), Positives = 43/91 (47%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCD 222
++ ++TG GIG + + G+ HV I + + + +++ + + V+F CD
Sbjct: 44 RVAIVTGGTDGIGYSTAKHLARLGM-HVIIAGNNDSKAKQVVSKIKEETLNDKVEFLYCD 102
Query: 223 VTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
+ + K ++ L V+INNA +M
Sbjct: 103 LASMTSIRQFVQKFKMKKIPLHVLINNAGVM 133
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 36.7 bits (81), Expect = 0.100
Identities = 44/192 (22%), Positives = 79/192 (41%), Gaps = 8/192 (4%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+ K+ ITG SGIG + + + G H I + +L G C+
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHGC-HTVIASRSLPRVLTAARKLAGATGRRCLPL-S 84
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVTALVTG 378
DV + D E G +D++IN AA S+ ++K +DI+ +G
Sbjct: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID----TSG 140
Query: 379 TLKAIEIM-GKQNGGKGGTVLNISSVAALCQSHLFPIYFGT-KSAVLQFSNCIGLEEHYA 552
T ++ K GG ++NI++ + ++ G+ K+AV + + +E +
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLG-NRGQALQVHAGSAKAAVDAMTRHLAVE--WG 197
Query: 553 KSGVRVLSICFG 588
+RV S+ G
Sbjct: 198 PQNIRVNSLAPG 209
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 36.7 bits (81), Expect = 0.100
Identities = 24/92 (26%), Positives = 47/92 (51%), Gaps = 3/92 (3%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN---CVK 207
+G++ +TG A+GIG+ +V+ +LE G +V I + ++ +EL P V
Sbjct: 17 QGQVAFVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAADELQANLPPTKQARVI 75
Query: 208 FYKCDVTVEELFLELFDTVKNEQGYLDVVINN 303
+C++ EE L + + G ++ ++NN
Sbjct: 76 PIQCNIRNEEEVNNLVKSTLDTFGKINFLVNN 107
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 36.7 bits (81), Expect = 0.100
Identities = 44/192 (22%), Positives = 79/192 (41%), Gaps = 8/192 (4%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+ K+ ITG SGIG + + + G H I + +L G C+
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHGC-HTVIASRSLPRVLTAARKLAGATGRRCLPL-S 84
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVTALVTG 378
DV + D E G +D++IN AA S+ ++K +DI+ +G
Sbjct: 85 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID----TSG 140
Query: 379 TLKAIEIM-GKQNGGKGGTVLNISSVAALCQSHLFPIYFGT-KSAVLQFSNCIGLEEHYA 552
T ++ K GG ++NI++ + ++ G+ K+AV + + +E +
Sbjct: 141 TFNVSRVLYEKFFRDHGGVIVNITATLG-NRGQALQVHAGSAKAAVDAMTRHLAVE--WG 197
Query: 553 KSGVRVLSICFG 588
+RV S+ G
Sbjct: 198 PQNIRVNSLAPG 209
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 36.3 bits (80), Expect = 0.13
Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 11/201 (5%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP---N 198
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP N
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 199 CVKFYKCDVTVEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTAL 369
F + DV+ L + V+ VV++ A I D + + + D + +
Sbjct: 69 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127
Query: 370 VTGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE- 186
Query: 544 HYAKSGVRVLSICFGATDTPL 606
+ G+R S+ G TP+
Sbjct: 187 -LGRHGIRCNSVLPGFIATPM 206
>BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 14
(all-trans/9-cis/11-cis) protein.
Length = 336
Score = 36.3 bits (80), Expect = 0.13
Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 12/108 (11%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHV-AILD--VAEDSGRALENELN--TKYGPNCV 204
GK VLITGA SG+G +L G + + D AE++ L EL + GP
Sbjct: 43 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPG 102
Query: 205 KFYKCDVTVEELFLELFDTVK-------NEQGYLDVVINNAAIMNDSY 327
++ V EL L +V+ E+ LDV+INNA I Y
Sbjct: 103 VSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPY 150
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 36.3 bits (80), Expect = 0.13
Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 11/201 (5%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP---N 198
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP N
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 199 CVKFYKCDVTVEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTAL 369
F + DV+ L + V+ VV++ A I D + + + D + +
Sbjct: 69 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127
Query: 370 VTGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE- 186
Query: 544 HYAKSGVRVLSICFGATDTPL 606
+ G+R S+ G TP+
Sbjct: 187 -LGRHGIRCNSVLPGFIATPM 206
>AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 36.3 bits (80), Expect = 0.13
Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 12/108 (11%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHV-AILD--VAEDSGRALENELN--TKYGPNCV 204
GK VLITGA SG+G +L G + + D AE++ L EL + GP
Sbjct: 43 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPG 102
Query: 205 KFYKCDVTVEELFLELFDTVK-------NEQGYLDVVINNAAIMNDSY 327
++ V EL L +V+ E+ LDV+INNA I Y
Sbjct: 103 VSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPY 150
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 36.3 bits (80), Expect = 0.13
Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 11/201 (5%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP---N 198
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP N
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 199 CVKFYKCDVTVEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTAL 369
F + DV+ L + V+ VV++ A I D + + + D + +
Sbjct: 69 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127
Query: 370 VTGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE- 186
Query: 544 HYAKSGVRVLSICFGATDTPL 606
+ G+R S+ G TP+
Sbjct: 187 -LGRHGIRCNSVLPGFIATPM 206
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 36.3 bits (80), Expect = 0.13
Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 11/201 (5%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP---N 198
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP N
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 199 CVKFYKCDVTVEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTAL 369
F + DV+ L + V+ VV++ A I D + + + D + +
Sbjct: 69 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127
Query: 370 VTGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE- 186
Query: 544 HYAKSGVRVLSICFGATDTPL 606
+ G+R S+ G TP+
Sbjct: 187 -LGRHGIRCNSVLPGFIATPM 206
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 36.3 bits (80), Expect = 0.13
Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 11/201 (5%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP---N 198
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP N
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 199 CVKFYKCDVTVEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTAL 369
F + DV+ L + V+ VV++ A I D + + + D + +
Sbjct: 69 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127
Query: 370 VTGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE- 186
Query: 544 HYAKSGVRVLSICFGATDTPL 606
+ G+R S+ G TP+
Sbjct: 187 -LGRHGIRCNSVLPGFIATPM 206
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 36.3 bits (80), Expect = 0.13
Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 11/201 (5%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP---N 198
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP N
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 199 CVKFYKCDVTVEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTAL 369
F + DV+ L + V+ VV++ A I D + + + D + +
Sbjct: 69 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127
Query: 370 VTGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE- 186
Query: 544 HYAKSGVRVLSICFGATDTPL 606
+ G+R S+ G TP+
Sbjct: 187 -LGRHGIRCNSVLPGFIATPM 206
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 36.3 bits (80), Expect = 0.13
Identities = 51/201 (25%), Positives = 86/201 (42%), Gaps = 11/201 (5%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP---N 198
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP N
Sbjct: 10 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 68
Query: 199 CVKFYKCDVTVEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTAL 369
F + DV+ L + V+ VV++ A I D + + + D + +
Sbjct: 69 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVN 127
Query: 370 VTGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 128 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE- 186
Query: 544 HYAKSGVRVLSICFGATDTPL 606
+ G+R S+ G TP+
Sbjct: 187 -LGRHGIRCNSVLPGFIATPM 206
>AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 36.3 bits (80), Expect = 0.13
Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 12/108 (11%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHV-AILD--VAEDSGRALENELN--TKYGPNCV 204
GK VLITGA SG+G +L G + + D AE++ L EL + GP
Sbjct: 43 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPG 102
Query: 205 KFYKCDVTVEELFLELFDTVK-------NEQGYLDVVINNAAIMNDSY 327
++ V EL L +V+ E+ LDV+INNA I Y
Sbjct: 103 VSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPY 150
>AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 36.3 bits (80), Expect = 0.13
Identities = 36/108 (33%), Positives = 49/108 (45%), Gaps = 12/108 (11%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHV-AILD--VAEDSGRALENELN--TKYGPNCV 204
GK VLITGA SG+G +L G + + D AE++ L EL + GP
Sbjct: 43 GKTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPG 102
Query: 205 KFYKCDVTVEELFLELFDTVK-------NEQGYLDVVINNAAIMNDSY 327
++ V EL L +V+ E+ LDV+INNA I Y
Sbjct: 103 VSGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPY 150
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 35.9 bits (79), Expect = 0.17
Identities = 68/264 (25%), Positives = 116/264 (43%), Gaps = 11/264 (4%)
Frame = +1
Query: 7 YVEHCVMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTK 186
Y E V+ + K V ITG SG G+ + R + RG++ +A + E L + + +
Sbjct: 18 YRERQVLSHLRDKYVFITGCDSGFGKLLARQLDARGLRVLAAC-LTEKGAEQLRGQTSDR 76
Query: 187 YGPNCVKFYKCDVTVEELFLELFDTVK---NEQGYLDVVINNAAIM-----ND--SYKSY 336
++ DVT E VK ++G L ++NNA I N+ + + +
Sbjct: 77 -----LETVTLDVTKTESVAAAAQWVKECVRDKG-LWGLVNNAGISLPTAPNELLTKQDF 130
Query: 337 KKQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQ 516
+D+N+ ++ TL + ++ K G V+N+SSV S Y +K V
Sbjct: 131 VTILDVNLLGVIDVTLSLLPLVRKAR----GRVVNVSSVMGRV-SLFGGGYCISKYGVEA 185
Query: 517 FSNCIGLEEHYAKSGVRVLSICFGATDTPLLNGTK-LGSFDEEIDGTCVEAIQKNYPIQK 693
FS+ + E Y GV+V I G T + + + L SF E D + E +++ Y +K
Sbjct: 186 FSDSLRRELSY--FGVKVAMIEPGYFKTAVTSKERFLKSFLEIWDRSSPE-VKEAYG-EK 241
Query: 694 MESAAKGLVEAYEHAKSGDTWIIT 765
+ K E E + D ++T
Sbjct: 242 FVADYKKSAEQMEQKCTQDLSLVT 265
>AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein.
Length = 198
Score = 35.9 bits (79), Expect = 0.17
Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 16/189 (8%)
Frame = +1
Query: 25 MESWKGKIV-LITGAASGIGEGVVRLILER-GVKHVAILDVAEDSG-RALENELNTKYGP 195
ME G+ V L+TGA+ G G + L+ V +L D R LE EL +
Sbjct: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60
Query: 196 NCVKFYKCDVTVEELFLELFDTVKN---EQGYLDVV-INNAAIMNDSYKSYKKQID---- 351
V D+ E +L ++ +G ++ INNA + D K + D
Sbjct: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120
Query: 352 -----INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQ 516
+N+T+++ T ++ + G TV+NISS+ AL + +Y K+A
Sbjct: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 517 FSNCIGLEE 543
+ LEE
Sbjct: 180 LFQVLALEE 188
>AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase
protein.
Length = 198
Score = 35.9 bits (79), Expect = 0.17
Identities = 49/189 (25%), Positives = 79/189 (41%), Gaps = 16/189 (8%)
Frame = +1
Query: 25 MESWKGKIV-LITGAASGIGEGVVRLILER-GVKHVAILDVAEDSG-RALENELNTKYGP 195
ME G+ V L+TGA+ G G + L+ V +L D R LE EL +
Sbjct: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60
Query: 196 NCVKFYKCDVTVEELFLELFDTVKN---EQGYLDVV-INNAAIMNDSYKSYKKQID---- 351
V D+ E +L ++ +G ++ INNA + D K + D
Sbjct: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120
Query: 352 -----INVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQ 516
+N+T+++ T ++ + G TV+NISS+ AL + +Y K+A
Sbjct: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179
Query: 517 FSNCIGLEE 543
+ LEE
Sbjct: 180 LFQVLALEE 188
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 35.1 bits (77), Expect = 0.30
Identities = 55/218 (25%), Positives = 90/218 (41%), Gaps = 6/218 (2%)
Frame = +1
Query: 46 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+VLITG +SGIG VRL + + K A L + GR E P ++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 390
DV + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 391 IEIMGKQNGGKG-GTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVR 567
++ +G G VL SV L +Y +K A+ C L GV
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGL--CESLAVLLLPFGVH 180
Query: 568 VLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNY 681
+ I G T + LGS +E +D T + + Y
Sbjct: 181 LSLIECGPVHTAFMEKV-LGSPEEVLDRTDIHTFHRFY 217
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.30
Identities = 55/218 (25%), Positives = 90/218 (41%), Gaps = 6/218 (2%)
Frame = +1
Query: 46 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+VLITG +SGIG VRL + + K A L + GR E P ++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 390
DV + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 391 IEIMGKQNGGKG-GTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVR 567
++ +G G VL SV L +Y +K A+ C L GV
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGL--CESLAVLLLPFGVH 180
Query: 568 VLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNY 681
+ I G T + LGS +E +D T + + Y
Sbjct: 181 LSLIECGPVHTAFMEKV-LGSPEEVLDRTDIHTFHRFY 217
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.30
Identities = 55/218 (25%), Positives = 90/218 (41%), Gaps = 6/218 (2%)
Frame = +1
Query: 46 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+VLITG +SGIG VRL + + K A L + GR E P ++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 390
DV + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 391 IEIMGKQNGGKG-GTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVR 567
++ +G G VL SV L +Y +K A+ C L GV
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGL--CESLAVLLLPFGVH 180
Query: 568 VLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNY 681
+ I G T + LGS +E +D T + + Y
Sbjct: 181 LSLIECGPVHTAFMEKV-LGSPEEVLDRTDIHTFHRFY 217
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 35.1 bits (77), Expect = 0.30
Identities = 55/218 (25%), Positives = 90/218 (41%), Gaps = 6/218 (2%)
Frame = +1
Query: 46 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+VLITG +SGIG VRL + + K A L + GR E P ++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 390
DV + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 391 IEIMGKQNGGKG-GTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVR 567
++ +G G VL SV L +Y +K A+ C L GV
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGL--CESLAVLLLPFGVH 180
Query: 568 VLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNY 681
+ I G T + LGS +E +D T + + Y
Sbjct: 181 LSLIECGPVHTAFMEKV-LGSPEEVLDRTDIHTFHRFY 217
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 35.1 bits (77), Expect = 0.30
Identities = 55/218 (25%), Positives = 90/218 (41%), Gaps = 6/218 (2%)
Frame = +1
Query: 46 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+VLITG +SGIG VRL + + K A L + GR E P ++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 390
DV + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 391 IEIMGKQNGGKG-GTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVR 567
++ +G G VL SV L +Y +K A+ C L GV
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGL--CESLAVLLLPFGVH 180
Query: 568 VLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNY 681
+ I G T + LGS +E +D T + + Y
Sbjct: 181 LSLIECGPVHTAFMEKV-LGSPEEVLDRTDIHTFHRFY 217
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.30
Identities = 55/218 (25%), Positives = 90/218 (41%), Gaps = 6/218 (2%)
Frame = +1
Query: 46 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+VLITG +SGIG VRL + + K A L + GR E P ++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 390
DV + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 391 IEIMGKQNGGKG-GTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVR 567
++ +G G VL SV L +Y +K A+ C L GV
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGL--CESLAVLLLPFGVH 180
Query: 568 VLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNY 681
+ I G T + LGS +E +D T + + Y
Sbjct: 181 LSLIECGPVHTAFMEKV-LGSPEEVLDRTDIHTFHRFY 217
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 35.1 bits (77), Expect = 0.30
Identities = 55/218 (25%), Positives = 90/218 (41%), Gaps = 6/218 (2%)
Frame = +1
Query: 46 IVLITGAASGIG-EGVVRLILE--RGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+VLITG +SGIG VRL + + K A L + GR E P ++ +
Sbjct: 5 VVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLETLQ 64
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAAI-MNDSYKSYKKQIDINVTAL-VTGTLKA 390
DV + + V +G +DV++ NA + + ++ + +V + V GT++
Sbjct: 65 LDVRDSKSVAAARERV--TEGRVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVVGTVRM 122
Query: 391 IEIMGKQNGGKG-GTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKSGVR 567
++ +G G VL SV L +Y +K A+ C L GV
Sbjct: 123 LQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGL--CESLAVLLLPFGVH 180
Query: 568 VLSICFGATDTPLLNGTKLGSFDEEIDGTCVEAIQKNY 681
+ I G T + LGS +E +D T + + Y
Sbjct: 181 LSLIECGPVHTAFMEKV-LGSPEEVLDRTDIHTFHRFY 217
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.30
Identities = 36/187 (19%), Positives = 80/187 (42%), Gaps = 7/187 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 125
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 378
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 126 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 182
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
+ + + G K G ++ ISS + + + +K+ + FS L+ YA
Sbjct: 183 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASK 239
Query: 559 GVRVLSI 579
G+ V S+
Sbjct: 240 GIFVQSL 246
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.30
Identities = 35/154 (22%), Positives = 66/154 (42%), Gaps = 10/154 (6%)
Frame = +1
Query: 193 PNC---VKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQ 345
P+C V Y CDV E + V+ E G + V++NNA +++ + + ++
Sbjct: 106 PHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERT 165
Query: 346 IDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
+ +N A T + M + N G ++ ++S L + Y +K V+ F
Sbjct: 166 MMVNCHAHFWTTKAFLPTMLEINHGH---IVTVASSLGLFSTAGVEDYCASKFGVVGFHE 222
Query: 526 CIGLEEHYA-KSGVRVLSICFGATDTPLLNGTKL 624
+ E A K G++ +C DT + G ++
Sbjct: 223 SLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRI 256
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 35.1 bits (77), Expect = 0.30
Identities = 36/187 (19%), Positives = 80/187 (42%), Gaps = 7/187 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 125
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 378
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 126 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 182
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
+ + + G K G ++ ISS + + + +K+ + FS L+ YA
Sbjct: 183 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASK 239
Query: 559 GVRVLSI 579
G+ V S+
Sbjct: 240 GIFVQSL 246
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.30
Identities = 35/154 (22%), Positives = 66/154 (42%), Gaps = 10/154 (6%)
Frame = +1
Query: 193 PNC---VKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQ 345
P+C V Y CDV E + V+ E G + V++NNA +++ + + ++
Sbjct: 106 PHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERT 165
Query: 346 IDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
+ +N A T + M + N G ++ ++S L + Y +K V+ F
Sbjct: 166 MMVNCHAHFWTTKAFLPTMLEINHGH---IVTVASSLGLFSTAGVEDYCASKFGVVGFHE 222
Query: 526 CIGLEEHYA-KSGVRVLSICFGATDTPLLNGTKL 624
+ E A K G++ +C DT + G ++
Sbjct: 223 SLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRI 256
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 35.1 bits (77), Expect = 0.30
Identities = 36/187 (19%), Positives = 80/187 (42%), Gaps = 7/187 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y
Sbjct: 46 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 104
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 378
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 105 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 161
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
+ + + G K G ++ ISS + + + +K+ + FS L+ YA
Sbjct: 162 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASK 218
Query: 559 GVRVLSI 579
G+ V S+
Sbjct: 219 GIFVQSL 225
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 35.1 bits (77), Expect = 0.30
Identities = 36/187 (19%), Positives = 80/187 (42%), Gaps = 7/187 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 125
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 378
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 126 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 182
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
+ + + G K G ++ ISS + + + +K+ + FS L+ YA
Sbjct: 183 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASK 239
Query: 559 GVRVLSI 579
G+ V S+
Sbjct: 240 GIFVQSL 246
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 35.1 bits (77), Expect = 0.30
Identities = 35/154 (22%), Positives = 66/154 (42%), Gaps = 10/154 (6%)
Frame = +1
Query: 193 PNC---VKFYKCDVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSY------KSYKKQ 345
P+C V Y CDV E + V+ E G + V++NNA +++ + + ++
Sbjct: 106 PHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHLLECPDELIERT 165
Query: 346 IDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
+ +N A T + M + N G ++ ++S L + Y +K V+ F
Sbjct: 166 MMVNCHAHFWTTKAFLPTMLEINHGH---IVTVASSLGLFSTAGVEDYCASKFGVVGFHE 222
Query: 526 CIGLEEHYA-KSGVRVLSICFGATDTPLLNGTKL 624
+ E A K G++ +C DT + G ++
Sbjct: 223 SLSHELKAAEKDGIKTTLVCPYLVDTGMFRGCRI 256
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 35.1 bits (77), Expect = 0.30
Identities = 36/187 (19%), Positives = 80/187 (42%), Gaps = 7/187 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y
Sbjct: 46 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 104
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 378
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 105 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 161
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
+ + + G K G ++ ISS + + + +K+ + FS L+ YA
Sbjct: 162 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSR--ALQYEYASK 218
Query: 559 GVRVLSI 579
G+ V S+
Sbjct: 219 GIFVQSL 225
>AY358093-1|AAQ88460.1| 152|Homo sapiens SDR1 protein.
Length = 152
Score = 34.7 bits (76), Expect = 0.40
Identities = 23/73 (31%), Positives = 34/73 (46%)
Frame = +1
Query: 49 VLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDVT 228
VLITG GIG + R ERG + + + E + E+ + G C ++ CDV
Sbjct: 26 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIR-QMGTEC-HYFICDVG 83
Query: 229 VEELFLELFDTVK 267
E E++ T K
Sbjct: 84 NRE---EVYQTAK 93
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 33.9 bits (74), Expect = 0.70
Identities = 27/85 (31%), Positives = 42/85 (49%)
Frame = +1
Query: 346 IDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSN 525
+DINV A T + M K+ GG+V+ +SS+AA S F Y +K+A+L +
Sbjct: 104 LDINVKAPALMTKAVVPEMEKRG---GGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTK 160
Query: 526 CIGLEEHYAKSGVRVLSICFGATDT 600
+ +E A +RV + G T
Sbjct: 161 TLAIE--LAPRNIRVNCLAPGLIKT 183
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.70
Identities = 35/187 (18%), Positives = 80/187 (42%), Gaps = 7/187 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 125
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 378
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 126 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 182
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
+ + + G K G ++ ISS + + + +++ + FS L+ YA
Sbjct: 183 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSR--ALQYEYASK 239
Query: 559 GVRVLSI 579
G+ V S+
Sbjct: 240 GIFVQSL 246
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 33.9 bits (74), Expect = 0.70
Identities = 35/187 (18%), Positives = 80/187 (42%), Gaps = 7/187 (3%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
G+ +++GA GIG+ + RG+ ++ ++ E+ + + ++ Y
Sbjct: 67 GRWAVVSGATDGIGKAYAEELASRGL-NIILISRNEEKLQVVAKDIADTYKVETDIIVAD 125
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQID-------INVTALVTG 378
+ E++L + + +K++ + +++NN + Y Y Q+ INV
Sbjct: 126 FSSGREIYLPIREALKDKD--VGILVNNVGVFY-PYPQYFTQLSEDKLWDIINVNIAAAS 182
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
+ + + G K G ++ ISS + + + +++ + FS L+ YA
Sbjct: 183 LMVHVVLPGMVE-RKKGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSR--ALQYEYASK 239
Query: 559 GVRVLSI 579
G+ V S+
Sbjct: 240 GIFVQSL 246
>AF165517-1|AAF86647.1| 223|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase type VII protein.
Length = 223
Score = 33.9 bits (74), Expect = 0.70
Identities = 28/92 (30%), Positives = 41/92 (44%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + F +K LD + NA IM
Sbjct: 63 DVSNLQSFFRASKELKQRFQRLDRIYLNAGIM 94
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 33.1 bits (72), Expect = 1.2
Identities = 50/201 (24%), Positives = 85/201 (42%), Gaps = 11/201 (5%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGV-VRLILERGVKHVAILD--VAEDSGRALENELNTKYGP---N 198
+ + L+TGA SGIG V VRL E LD A+++ R L +K GP N
Sbjct: 8 RSALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGP-GSKEGPPRGN 66
Query: 199 CVKFYKCDVTVEELFLELFDTVKN-EQGYLDVVINNAAIMNDSYKSYKKQIDIN--VTAL 369
F + DV+ L + V+ VV++ A I D + + + D + +
Sbjct: 67 HAAF-QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSRDDWDKVIAVN 125
Query: 370 VTGTLKAIEIMGKQ--NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEE 543
+ GT + + + G G+++NISS+ + Y +K+ V+ + E
Sbjct: 126 LKGTFLVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARE- 184
Query: 544 HYAKSGVRVLSICFGATDTPL 606
+ G+ S+ G TP+
Sbjct: 185 -LGRHGIPCNSVLPGFIATPM 204
>X64228-1|CAA45535.1| 2090|Homo sapiens putative oncogene protein.
Length = 2090
Score = 32.7 bits (71), Expect = 1.6
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = -2
Query: 674 FWMASTQVPSISSSKLPSLVPFNSGVSVAPKQILSTRTPLLA*CSSNPIQ 525
F A+T P SS P + PF+S A LS TPL A SS P++
Sbjct: 591 FTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLK 640
>BC045620-1|AAH45620.2| 2090|Homo sapiens nucleoporin 214kDa
protein.
Length = 2090
Score = 32.7 bits (71), Expect = 1.6
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = -2
Query: 674 FWMASTQVPSISSSKLPSLVPFNSGVSVAPKQILSTRTPLLA*CSSNPIQ 525
F A+T P SS P + PF+S A LS TPL A SS P++
Sbjct: 591 FTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLK 640
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 32.7 bits (71), Expect = 1.6
Identities = 48/215 (22%), Positives = 91/215 (42%), Gaps = 10/215 (4%)
Frame = +1
Query: 7 YVEHCVMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTK 186
Y E V+ + K V ITG SG G + R + RG++ +A + E L + + +
Sbjct: 18 YRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC-LTEKGAEQLRGQTSDR 76
Query: 187 YGPNCVKFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYK 339
++ DVT E VK G + ++NNA I+ + +
Sbjct: 77 -----LETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSM 131
Query: 340 KQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQF 519
+ +N+ ++ TL + ++ + G ++N+SS+ + Y +K V F
Sbjct: 132 NMLKVNLIGVIQVTLSMLPLVRRAR----GRIVNVSSILGRV-AFFVGGYCVSKYGVEAF 186
Query: 520 SNCIGLE-EHYAKSGVRVLSICFGATDTPLLNGTK 621
S+ + E +H+ GV++ + G T + N T+
Sbjct: 187 SDILRREIQHF---GVKISIVEPGYFRTGMTNMTQ 218
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 32.7 bits (71), Expect = 1.6
Identities = 44/211 (20%), Positives = 86/211 (40%), Gaps = 8/211 (3%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPN-CVKFYKC 219
++ ++TG+ SGIG + R + G HV I + + ++ + G V C
Sbjct: 37 RVAVVTGSTSGIGFAIARRLARDGA-HVVISSRKQQN---VDRAMAKLQGEGLSVAGIVC 92
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAI-------MNDSYKSYKKQIDINVTALVTG 378
V E +L G +D ++ +A + + S + + K + +NV +
Sbjct: 93 HVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVK---SP 149
Query: 379 TLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNCIGLEEHYAKS 558
L +++ +G +L +SS+AA +Y +K+A+L + + LE A
Sbjct: 150 ALLLSQLLPYMENRRGAVIL-VSSIAAYNPVVALGVYNVSKTALLGLTRTLALE--LAPK 206
Query: 559 GVRVLSICFGATDTPLLNGTKLGSFDEEIDG 651
+RV + G T ++G + G
Sbjct: 207 DIRVNCVVPGIIKTDFSKVVRIGFMGMSLSG 237
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 32.7 bits (71), Expect = 1.6
Identities = 29/140 (20%), Positives = 61/140 (43%), Gaps = 1/140 (0%)
Frame = +1
Query: 40 GKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
GK V++TGA +GIG+ + RG ++ + + A ++ + + V
Sbjct: 38 GKTVIVTGANTGIGKQTALELARRG-GNIILACRDMEKCEAAAKDIRGETLNHHVNARHL 96
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIMNDSYKSYKKQIDINVTALVTG-TLKAIE 396
D+ + E + E+ +D++INNA +M + + + ++ G L
Sbjct: 97 DLASLKSIREFAAKIIEEEERVDILINNAGVMRCPHWTTEDGFEMQFGVNHLGHFLLTNL 156
Query: 397 IMGKQNGGKGGTVLNISSVA 456
++ K ++N+SS+A
Sbjct: 157 LLDKLKASAPSRIINLSSLA 176
>AL157938-9|CAI41111.1| 2090|Homo sapiens nucleoporin 214kDa
protein.
Length = 2090
Score = 32.7 bits (71), Expect = 1.6
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = -2
Query: 674 FWMASTQVPSISSSKLPSLVPFNSGVSVAPKQILSTRTPLLA*CSSNPIQ 525
F A+T P SS P + PF+S A LS TPL A SS P++
Sbjct: 591 FTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLK 640
>AL157938-8|CAI41109.1| 1684|Homo sapiens nucleoporin 214kDa
protein.
Length = 1684
Score = 32.7 bits (71), Expect = 1.6
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = -2
Query: 674 FWMASTQVPSISSSKLPSLVPFNSGVSVAPKQILSTRTPLLA*CSSNPIQ 525
F A+T P SS P + PF+S A LS TPL A SS P++
Sbjct: 184 FTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLK 233
>AJ298318-1|CAC83675.1| 1349|Homo sapiens mucin 5 protein.
Length = 1349
Score = 32.7 bits (71), Expect = 1.6
Identities = 18/64 (28%), Positives = 33/64 (51%)
Frame = -2
Query: 263 TVSNNSRKSSSTVTSHL*NFTQLGPYFVLSSFSRALPESSATSKIATCLTPRSNISRTTP 84
T S NS ++ST+++ + +SS + + + TSK + + ++ S TTP
Sbjct: 1142 TTSTNSAPTTSTISASTTSTISAPTTSTISSPTSSTTSTPQTSKTSAATSSTTSGSGTTP 1201
Query: 83 SPIP 72
SP+P
Sbjct: 1202 SPVP 1205
Score = 30.7 bits (66), Expect = 6.5
Identities = 27/90 (30%), Positives = 39/90 (43%), Gaps = 5/90 (5%)
Frame = -2
Query: 263 TVSNNSRKSSSTVTSHL*NFTQLGPYFVLSSFSRALPESSATSKIATCLTPRSNISRT-- 90
T+S + ++S T+ + + L + +P +S TS T T S S+T
Sbjct: 68 TISAPTTSTTSAPTTSTTSASTASKTSGLGTTPSPIPTTSTTSPPTTSTTSASTASKTSG 127
Query: 89 ---TPSPIPLAAPVISTIFPFHDSITQCST 9
TPSP+ P STIF S T ST
Sbjct: 128 PGTTPSPV----PTTSTIFAPRTSTTSAST 153
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 32.7 bits (71), Expect = 1.6
Identities = 48/215 (22%), Positives = 91/215 (42%), Gaps = 10/215 (4%)
Frame = +1
Query: 7 YVEHCVMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTK 186
Y E V+ + K V ITG SG G + R + RG++ +A + E L + + +
Sbjct: 18 YRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC-LTEKGAEQLRGQTSDR 76
Query: 187 YGPNCVKFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYK 339
++ DVT E VK G + ++NNA I+ + +
Sbjct: 77 -----LETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSM 131
Query: 340 KQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQF 519
+ +N+ ++ TL + ++ + G ++N+SS+ + Y +K V F
Sbjct: 132 NMLKVNLIGVIQVTLSMLPLVRRAR----GRIVNVSSILGRV-AFFVGGYCVSKYGVEAF 186
Query: 520 SNCIGLE-EHYAKSGVRVLSICFGATDTPLLNGTK 621
S+ + E +H+ GV++ + G T + N T+
Sbjct: 187 SDILRREIQHF---GVKISIVEPGYFRTGMTNMTQ 218
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 32.7 bits (71), Expect = 1.6
Identities = 48/215 (22%), Positives = 91/215 (42%), Gaps = 10/215 (4%)
Frame = +1
Query: 7 YVEHCVMESWKGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTK 186
Y E V+ + K V ITG SG G + R + RG++ +A + E L + + +
Sbjct: 18 YRERQVVSHLQDKYVFITGCDSGFGNLLARQLDARGLRVLAAC-LTEKGAEQLRGQTSDR 76
Query: 187 YGPNCVKFYKCDVTVEELFLELFDTVKNEQGYLDV--VINNAAIMND-------SYKSYK 339
++ DVT E VK G + ++NNA I+ + +
Sbjct: 77 -----LETVTLDVTKMESIAAATQWVKEHVGDRGLWGLVNNAGILTPITLCEWLNTEDSM 131
Query: 340 KQIDINVTALVTGTLKAIEIMGKQNGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQF 519
+ +N+ ++ TL + ++ + G ++N+SS+ + Y +K V F
Sbjct: 132 NMLKVNLIGVIQVTLSMLPLVRRAR----GRIVNVSSILGRV-AFFVGGYCVSKYGVEAF 186
Query: 520 SNCIGLE-EHYAKSGVRVLSICFGATDTPLLNGTK 621
S+ + E +H+ GV++ + G T + N T+
Sbjct: 187 SDILRREIQHF---GVKISIVEPGYFRTGMTNMTQ 218
>AB159230-1|BAD07398.1| 2091|Homo sapiens KIAA0023 splice variant 1
protein.
Length = 2091
Score = 32.7 bits (71), Expect = 1.6
Identities = 20/50 (40%), Positives = 25/50 (50%)
Frame = -2
Query: 674 FWMASTQVPSISSSKLPSLVPFNSGVSVAPKQILSTRTPLLA*CSSNPIQ 525
F A+T P SS P + PF+S A LS TPL A SS P++
Sbjct: 592 FTAAATSTPVSSSQSAPPMSPFSSASKPAASGPLSHPTPLSAPPSSVPLK 641
>AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 32.3 bits (70), Expect = 2.1
Identities = 45/192 (23%), Positives = 80/192 (41%), Gaps = 8/192 (4%)
Frame = +1
Query: 37 KGKIVLITGAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYK 216
+ K+ ITG SGIG + + + G H A +A +GR C+
Sbjct: 27 RDKVAFITGGGSGIGFRIAEIFMRHGC-HTAARKLAGATGR------------RCLPL-S 72
Query: 217 CDVTVEELFLELFDTVKNEQGYLDVVINNAA------IMNDSYKSYKKQIDINVTALVTG 378
DV + D E G +D++IN AA S+ ++K +DI+ +G
Sbjct: 73 MDVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID----TSG 128
Query: 379 TLKAIEIM-GKQNGGKGGTVLNISSVAALCQSHLFPIYFGT-KSAVLQFSNCIGLEEHYA 552
T ++ K GG ++NI++ + ++ G+ K+AV + + +E +
Sbjct: 129 TFNVSRVLYEKFFRDHGGVIVNITATLG-NRGQALQVHAGSAKAAVDAMTRHLAVE--WG 185
Query: 553 KSGVRVLSICFG 588
+RV S+ G
Sbjct: 186 PQNIRVNSLAPG 197
>BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein.
Length = 341
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 111
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 7 protein.
Length = 341
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens
cDNA FLJ12867 fis, clone NT2RP2003702, highly similar to
Homo sapiens 17 beta-hydroxysteroid dehydrogenase type
VII ).
Length = 155
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 7 protein.
Length = 341
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protein
protein.
Length = 341
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase type VII protein.
Length = 341
Score = 31.9 bits (69), Expect = 2.8
Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Frame = +1
Query: 43 KIVLITGAASGIGEGVV-RLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKC 219
K+VLITGA+SGIG + RL+ E H+ + A+ L + V +
Sbjct: 3 KVVLITGASSGIGLALCKRLLAEDDELHLCLACRNMSKAEAVCAALLASHPTAEVTIVQV 62
Query: 220 DVTVEELFLELFDTVKNEQGYLDVVINNAAIM 315
DV+ + +K LD + NA IM
Sbjct: 63 DVSNLQSVFRASKELKQRFQRLDCIYLNAGIM 94
>BC111965-1|AAI11966.1| 863|Homo sapiens AP2 associated kinase 1
protein.
Length = 863
Score = 31.5 bits (68), Expect = 3.7
Identities = 35/159 (22%), Positives = 66/159 (41%), Gaps = 3/159 (1%)
Frame = +1
Query: 61 GAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDVTVEEL 240
G+ SG+G G + + G + V + +V + G A+ + T G C ++ +
Sbjct: 25 GSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKC--------ALKRM 76
Query: 241 FLELFDTVKNEQGYLDVVINNAAIMND--SYKSYKKQIDINVTALVTGTL-KAIEIMGKQ 411
F V NE L V IM D +K+ ID ++ + +G + + + +M
Sbjct: 77 F------VNNEHD-LQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFC 129
Query: 412 NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNC 528
GG+ ++N ++ + I+ T AV + C
Sbjct: 130 RGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQC 168
>BC104842-1|AAI04843.1| 863|Homo sapiens AP2 associated kinase 1
protein.
Length = 863
Score = 31.5 bits (68), Expect = 3.7
Identities = 35/159 (22%), Positives = 66/159 (41%), Gaps = 3/159 (1%)
Frame = +1
Query: 61 GAASGIGEGVVRLILERGVKHVAILDVAEDSGRALENELNTKYGPNCVKFYKCDVTVEEL 240
G+ SG+G G + + G + V + +V + G A+ + T G C ++ +
Sbjct: 25 GSTSGLGSGYIGRVFGIGRQQVTVDEVLAEGGFAIVFLVRTSNGMKC--------ALKRM 76
Query: 241 FLELFDTVKNEQGYLDVVINNAAIMND--SYKSYKKQIDINVTALVTGTL-KAIEIMGKQ 411
F V NE L V IM D +K+ ID ++ + +G + + + +M
Sbjct: 77 F------VNNEHD-LQVCKREIQIMRDLSGHKNIVGYIDSSINNVSSGDVWEVLILMDFC 129
Query: 412 NGGKGGTVLNISSVAALCQSHLFPIYFGTKSAVLQFSNC 528
GG+ ++N ++ + I+ T AV + C
Sbjct: 130 RGGQVVNLMNQRLQTGFTENEVLQIFCDTCEAVARLHQC 168
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 120,876,636
Number of Sequences: 237096
Number of extensions: 2724325
Number of successful extensions: 7057
Number of sequences better than 10.0: 267
Number of HSP's better than 10.0 without gapping: 6490
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6946
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 10092110758
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -