Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV17i19f
(777 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein. 119 1e-26
BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase... 119 1e-26
BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase... 119 1e-26
AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein. 119 1e-26
AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein. 119 1e-26
BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta... 115 2e-25
BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta... 115 2e-25
BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta... 115 2e-25
BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta... 115 2e-25
BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase... 115 2e-25
BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase... 115 2e-25
AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H pr... 115 2e-25
AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein. 115 2e-25
AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen HD-C... 115 2e-25
AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein. 115 2e-25
AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain deh... 115 2e-25
AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain deh... 115 2e-25
BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein. 114 4e-25
AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens ... 114 4e-25
BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta... 112 1e-24
BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta... 112 1e-24
AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein. 112 1e-24
AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain deh... 112 1e-24
AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase... 111 4e-24
U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein. 110 5e-24
BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein. 110 5e-24
AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol deh... 110 5e-24
BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase... 107 6e-23
BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal trans-2-eno... 103 5e-22
AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-eno... 103 5e-22
AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein. 103 5e-22
AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein. 103 5e-22
AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA... 102 2e-21
DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retin... 99 9e-21
BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase... 99 9e-21
AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein. 99 9e-21
AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein prot... 99 9e-21
AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol... 99 9e-21
AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain... 99 2e-20
AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens ... 98 3e-20
BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta... 97 8e-20
BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta... 97 8e-20
AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein. 97 8e-20
AY268355-1|AAP42289.1| 300|Homo sapiens short-chain dehydrogena... 97 8e-20
AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid ... 97 8e-20
AB073347-1|BAD38632.1| 300|Homo sapiens putative protein produc... 97 8e-20
BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta... 94 4e-19
AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase h... 94 4e-19
M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid de... 93 1e-18
BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta... 93 1e-18
AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid ... 93 1e-18
AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta... 93 1e-18
AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta... 93 1e-18
AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II p... 92 2e-18
BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 91 5e-18
BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for IM... 91 5e-18
BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 91 5e-18
AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 91 5e-18
AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 91 5e-18
AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose r... 91 5e-18
AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase prot... 91 5e-18
AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl reduc... 91 5e-18
BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 87 5e-17
BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 87 5e-17
DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin de... 87 7e-17
BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin de... 87 7e-17
BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate dehyd... 87 7e-17
L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 87 9e-17
J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent 15-hydroxy... 87 9e-17
BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 87 9e-17
BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate dehyd... 87 9e-17
AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA pro... 87 9e-17
BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4 pr... 85 2e-16
BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4 pr... 85 2e-16
AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein. 85 2e-16
BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase... 85 3e-16
BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid dehydrog... 82 2e-15
AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-l... 82 2e-15
AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens ... 82 2e-15
AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-l... 82 2e-15
AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens ... 82 2e-15
X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein. 81 3e-15
M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate deh... 81 3e-15
BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma var... 81 3e-15
BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein. 81 3e-15
BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma var... 81 3e-15
BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid dehydrog... 81 4e-15
BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid dehydrog... 81 4e-15
BC002731-1|AAH02731.2| 260|Homo sapiens short-chain dehydrogena... 81 6e-15
AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein. 81 6e-15
AY313894-1|AAP83166.1| 315|Homo sapiens short-chain dehydrogena... 81 6e-15
AY268352-1|AAP42286.1| 286|Homo sapiens short-chain dehydrogena... 81 6e-15
BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid dehydrog... 80 8e-15
BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid dehydrog... 80 1e-14
AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid dehydrog... 80 1e-14
AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid dehydrog... 80 1e-14
AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens ... 79 1e-14
AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase... 79 1e-14
AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer seg... 79 2e-14
U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid deh... 78 3e-14
CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein. 78 3e-14
BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta... 78 3e-14
AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta... 78 3e-14
AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta... 78 3e-14
BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein. 78 4e-14
CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein. 77 5e-14
BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 1... 77 5e-14
BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 1... 77 5e-14
BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein. 77 5e-14
BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 1... 77 5e-14
AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein. 77 5e-14
AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protei... 77 5e-14
AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated shor... 77 5e-14
AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein. 77 5e-14
BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 1... 77 7e-14
AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein. 77 7e-14
AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens ... 76 1e-13
BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5... 75 2e-13
U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogen... 75 4e-13
AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase p... 75 4e-13
X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid deh... 73 1e-12
BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta... 73 1e-12
AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid ... 73 1e-12
AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain deh... 73 2e-12
BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta... 72 2e-12
U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific de... 72 3e-12
BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal dehyd... 71 4e-12
BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal dehyd... 71 4e-12
BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase... 71 4e-12
AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase... 71 4e-12
AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase... 71 4e-12
AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase... 71 4e-12
AF179237-1|AAD55402.1| 302|Homo sapiens short-chain dehydrogena... 71 4e-12
AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain deh... 71 4e-12
BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta... 69 1e-11
AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimer... 69 1e-11
AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein. 69 1e-11
X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin ... 68 4e-11
BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 67 6e-11
AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reducta... 67 6e-11
AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal 2,4-dienoyl... 67 6e-11
AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A... 67 6e-11
L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid dehydro... 66 1e-10
L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid de... 66 1e-10
BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta... 66 1e-10
BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta... 66 1e-10
AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta... 66 1e-10
AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta... 66 1e-10
AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens ... 66 1e-10
U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 65 3e-10
U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 65 3e-10
L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase... 65 3e-10
BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 65 3e-10
BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reducta... 65 3e-10
AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol dehydrog... 65 3e-10
AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reducta... 65 3e-10
Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta) ... 64 5e-10
U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide bind... 64 5e-10
U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol dehyd... 64 5e-10
CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein. 64 5e-10
BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta... 64 5e-10
BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta... 64 5e-10
BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta... 64 5e-10
AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-bet... 64 5e-10
AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta... 64 5e-10
AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-bet... 64 5e-10
AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-bet... 64 5e-10
AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-bet... 64 5e-10
AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain ty... 64 5e-10
AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid d... 64 5e-10
AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid d... 64 5e-10
U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid de... 64 7e-10
EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta... 64 7e-10
BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta... 64 7e-10
BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta... 64 7e-10
U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 63 9e-10
D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-cha... 63 9e-10
U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid de... 62 2e-09
CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein. 62 2e-09
BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein. 62 2e-09
AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein. 62 2e-09
AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens ... 62 2e-09
BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain dehy... 61 5e-09
BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain dehy... 61 5e-09
AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase s... 61 5e-09
BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase... 60 9e-09
AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase... 60 9e-09
BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 1... 60 1e-08
AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein. 60 1e-08
AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 1... 60 1e-08
DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 1... 59 2e-08
AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens ... 59 2e-08
CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase... 59 2e-08
BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase... 59 2e-08
BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase... 59 2e-08
BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein. 59 2e-08
BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 1... 59 2e-08
AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein. 59 2e-08
AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein. 59 2e-08
AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein. 59 2e-08
AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase p... 59 2e-08
AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-depende... 59 2e-08
AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-depende... 59 2e-08
AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-depende... 59 2e-08
AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid ... 59 2e-08
AF295380-1|AAL37037.1| 319|Homo sapiens short-chain dehydrogena... 59 2e-08
AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein. 59 2e-08
AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase p... 59 2e-08
AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein. 59 2e-08
AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein. 59 2e-08
X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for ... 58 3e-08
U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 58 3e-08
M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid de... 58 3e-08
M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental... 58 3e-08
M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol... 58 3e-08
BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta... 58 3e-08
BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta... 58 3e-08
DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retin... 57 6e-08
M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase pro... 56 1e-07
BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase (... 56 1e-07
AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase (... 55 2e-07
U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha hydroxy... 55 3e-07
M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein. 55 3e-07
J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein. 55 3e-07
EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1 pr... 55 3e-07
CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein. 55 3e-07
BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1 pr... 55 3e-07
BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1 pr... 55 3e-07
BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1 pr... 55 3e-07
AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase (NAP... 55 3e-07
AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1 pr... 55 3e-07
AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1 pr... 55 3e-07
AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase prot... 55 3e-07
AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase... 54 8e-07
AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reducta... 53 1e-06
AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic reticulum-a... 53 1e-06
AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein. 53 1e-06
AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase p... 53 1e-06
Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta) ... 52 2e-06
BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta... 52 2e-06
BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 1... 51 4e-06
U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin d... 51 5e-06
AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase h... 50 9e-06
AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reducta... 50 9e-06
CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase... 50 1e-05
BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase... 50 1e-05
M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid de... 49 2e-05
BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein. 49 2e-05
AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retin... 49 2e-05
AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol ... 49 2e-05
EF462915-1|ABO43035.1| 277|Homo sapiens carbonyl reductase 3 pr... 49 2e-05
CR541709-1|CAG46510.1| 277|Homo sapiens CBR3 protein. 49 2e-05
BC002812-1|AAH02812.1| 277|Homo sapiens carbonyl reductase 3 pr... 49 2e-05
AP001725-1|BAA95547.1| 277|Homo sapiens carbonyl reductase (NAD... 49 2e-05
AP000689-1|BAA89425.1| 277|Homo sapiens carbonyl reductase 3 pr... 49 2e-05
AK223429-1|BAD97149.1| 277|Homo sapiens carbonyl reductase 3 va... 49 2e-05
AB124847-1|BAE45939.1| 277|Homo sapiens carbonyl reductase 3 pr... 49 2e-05
AB041012-1|BAD74062.1| 277|Homo sapiens NADPH-dependent carbony... 49 2e-05
AB004854-1|BAA33500.1| 277|Homo sapiens carbonyl reductase 3 pr... 49 2e-05
AB003151-2|BAA34207.1| 277|Homo sapiens carbonyl reductase 3 pr... 49 2e-05
DQ088988-1|AAZ85982.1| 118|Homo sapiens DHRS4L2 isoform 2 protein. 48 4e-05
AK024022-1|BAB14782.1| 219|Homo sapiens protein ( Homo sapiens ... 48 5e-05
BC026024-1|AAH26024.1| 312|Homo sapiens DHRS12 protein protein. 47 7e-05
BC015582-1|AAH15582.1| 327|Homo sapiens dehydrogenase/reductase... 46 2e-04
BC011968-1|AAH11968.1| 244|Homo sapiens DECR2 protein protein. 45 4e-04
Z97054-9|CAI42651.1| 169|Homo sapiens hydroxysteroid (17-beta) ... 44 5e-04
CR457356-1|CAG33637.1| 181|Homo sapiens MGC4172 protein. 44 8e-04
AK026196-1|BAB15390.1| 181|Homo sapiens protein ( Homo sapiens ... 44 8e-04
AF325429-1|AAL05450.1| 189|Homo sapiens WW domain-containing ox... 42 0.002
AF227528-1|AAF82055.1| 189|Homo sapiens FOR III protein protein. 42 0.002
AF187015-1|AAF31694.1| 189|Homo sapiens truncated WW-domain oxi... 42 0.002
AF162767-1|AAF14537.1| 341|Homo sapiens 17beta-hydroxysteroid d... 42 0.002
CR381696-1|CAI95409.1| 245|Homo sapiens dehydrogenase/reductase... 41 0.004
BX649443-1|CAI95430.1| 245|Homo sapiens dehydrogenase/reductase... 41 0.004
AY256821-1|AAP94227.1| 526|Homo sapiens WOX8 isoform 8 protein. 41 0.004
AF325432-1|AAL05449.1| 414|Homo sapiens WW domain-containing ox... 41 0.004
AF227527-1|AAF82054.1| 414|Homo sapiens FOR II protein protein. 41 0.004
AF227526-1|AAF82053.1| 363|Homo sapiens FOR I protein protein. 41 0.004
AF211943-1|AAF27049.1| 414|Homo sapiens WW domain-containing pr... 41 0.004
CR457145-1|CAG33426.1| 157|Homo sapiens PECR protein. 41 0.006
BT007445-1|AAP36113.1| 234|Homo sapiens WW domain containing ox... 41 0.006
BC003184-1|AAH03184.1| 234|Homo sapiens WWOX protein protein. 41 0.006
AF395123-1|AAK81727.1| 234|Homo sapiens WWOXdelta6-8 protein. 41 0.006
BC012536-1|AAH12536.1| 98|Homo sapiens HSD17B12 protein protein. 40 0.008
AY268353-1|AAP42287.1| 199|Homo sapiens short-chain dehydrogena... 40 0.008
AY186250-1|AAO72314.1| 264|Homo sapiens 17-beta hydroxysteroid ... 40 0.010
BT007075-1|AAP35738.1| 341|Homo sapiens hydroxysteroid (17-beta... 39 0.023
BC065246-1|AAH65246.1| 341|Homo sapiens hydroxysteroid (17-beta... 39 0.023
BC007068-1|AAH07068.1| 341|Homo sapiens hydroxysteroid (17-beta... 39 0.023
AY358962-1|AAQ89321.1| 341|Homo sapiens HSD17B7 protein. 39 0.023
AL445197-8|CAI15947.1| 341|Homo sapiens hydroxysteroid (17-beta... 39 0.023
AL445197-7|CAI15946.1| 111|Homo sapiens hydroxysteroid (17-beta... 39 0.023
AL392003-2|CAI13457.1| 341|Homo sapiens hydroxysteroid (17-beta... 39 0.023
AK022929-1|BAB14312.1| 155|Homo sapiens protein ( Homo sapiens ... 39 0.023
AJ249179-1|CAC20418.1| 341|Homo sapiens 17beta-hydroxysteroid d... 39 0.023
AF145023-1|AAP97275.1| 341|Homo sapiens ovarian-specific protei... 39 0.023
AF098786-1|AAF09266.2| 341|Homo sapiens 17 beta-hydroxysteroid ... 39 0.023
BC018336-1|AAH18336.1| 87|Homo sapiens Unknown (protein for MG... 38 0.040
AJ250550-1|CAC88111.1| 341|Homo sapiens 17beta hydroxysteroid d... 38 0.040
AY444559-1|AAS68535.1| 265|Homo sapiens retinal short chain deh... 37 0.070
AF165517-1|AAF86647.1| 223|Homo sapiens 17-beta-hydroxysteroid ... 36 0.16
BC112187-1|AAI12188.1| 181|Homo sapiens HSD11B1L protein protein. 36 0.21
BC093950-1|AAH93950.1| 181|Homo sapiens HSD11B1L protein protein. 36 0.21
AY313896-1|AAP83168.1| 234|Homo sapiens short-chain dehydrogena... 36 0.21
AY268351-1|AAP42285.1| 205|Homo sapiens short-chain dehydrogena... 36 0.21
AF240697-1|AAF82747.1| 172|Homo sapiens retinol dehydrogenase h... 36 0.21
BC004331-1|AAH04331.1| 345|Homo sapiens HSDL2 protein protein. 34 0.50
AL162732-2|CAM17151.1| 345|Homo sapiens hydroxysteroid dehydrog... 34 0.50
D86058-1|BAA12983.1| 281|Homo sapiens h1-calponin protein. 33 0.87
AY358093-1|AAQ88460.1| 152|Homo sapiens SDR1 protein. 33 1.1
U37019-1|AAC51780.1| 297|Homo sapiens smooth muscle cell calpon... 33 1.5
S80560-1|AAB35751.1| 297|Homo sapiens basic calponin protein. 33 1.5
D17408-1|BAA04231.1| 297|Homo sapiens calponin protein. 33 1.5
DQ426869-1|ABD90534.1| 69|Homo sapiens dehydrogenase/reductase... 33 1.5
BC072434-1|AAH72434.1| 152|Homo sapiens HSD11B1L protein protein. 33 1.5
BC053546-1|AAH53546.1| 152|Homo sapiens hydroxysteroid (11-beta... 33 1.5
BC036307-1|AAH36307.2| 297|Homo sapiens calponin 1, basic, smoo... 33 1.5
BC022015-1|AAH22015.1| 297|Homo sapiens calponin 1, basic, smoo... 33 1.5
AY313895-1|AAP83167.1| 181|Homo sapiens short-chain dehydrogena... 33 1.5
AY268354-1|AAP42288.1| 152|Homo sapiens short-chain dehydrogena... 33 1.5
AK223234-1|BAD96954.1| 297|Homo sapiens calponin 1, basic, smoo... 33 1.5
DQ338571-1|ABC61321.1| 160|Homo sapiens NADP(H)-dependent retin... 32 2.0
AL023881-2|CAO77955.1| 81|Homo sapiens 2,4-dienoyl CoA reducta... 32 2.6
BC071987-1|AAH71987.1| 229|Homo sapiens HSD17B7P2 protein protein. 31 4.6
AY829267-1|AAV87307.1| 229|Homo sapiens 17beta-hydroxysteroid d... 31 4.6
AB032254-1|BAA89211.1| 1878|Homo sapiens bromodomain adjacent to... 30 8.1
>CR457124-1|CAG33405.1| 325|Homo sapiens DKFZp566O084 protein.
Length = 325
Score = 119 bits (286), Expect = 1e-26
Identities = 70/193 (36%), Positives = 103/193 (53%), Gaps = 4/193 (2%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKI---KPLV 283
N VV+ITGA+SG+G E A F AKLVL GR L+ + + + +K+ KP +
Sbjct: 52 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYL 111
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
V D+ + + + + + +D+LVNNAG+ GTI T++ R+M TN GP
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPV 171
Query: 464 YLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P +IK + G+IV +SS+ G S P AY SK A F C+ E+ +
Sbjct: 172 ALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 231
Query: 641 VNAVNPGVITTGL 679
V ++PG I T L
Sbjct: 232 VTVISPGYIHTNL 244
>BC009679-1|AAH09679.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 119 bits (286), Expect = 1e-26
Identities = 70/193 (36%), Positives = 103/193 (53%), Gaps = 4/193 (2%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKI---KPLV 283
N VV+ITGA+SG+G E A F AKLVL GR L+ + + + +K+ KP +
Sbjct: 52 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYL 111
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
V D+ + + + + + +D+LVNNAG+ GTI T++ R+M TN GP
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPV 171
Query: 464 YLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P +IK + G+IV +SS+ G S P AY SK A F C+ E+ +
Sbjct: 172 ALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 231
Query: 641 VNAVNPGVITTGL 679
V ++PG I T L
Sbjct: 232 VTVISPGYIHTNL 244
>BC004126-1|AAH04126.1| 325|Homo sapiens dehydrogenase/reductase
(SDR family) member 7B protein.
Length = 325
Score = 119 bits (286), Expect = 1e-26
Identities = 70/193 (36%), Positives = 103/193 (53%), Gaps = 4/193 (2%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKI---KPLV 283
N VV+ITGA+SG+G E A F AKLVL GR L+ + + + +K+ KP +
Sbjct: 52 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYL 111
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
V D+ + + + + + +D+LVNNAG+ GTI T++ R+M TN GP
Sbjct: 112 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPV 171
Query: 464 YLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P +IK + G+IV +SS+ G S P AY SK A F C+ E+ +
Sbjct: 172 ALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 231
Query: 641 VNAVNPGVITTGL 679
V ++PG I T L
Sbjct: 232 VTVISPGYIHTNL 244
>AY358498-1|AAQ88862.1| 310|Homo sapiens DFIT212 protein.
Length = 310
Score = 119 bits (286), Expect = 1e-26
Identities = 70/193 (36%), Positives = 103/193 (53%), Gaps = 4/193 (2%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKI---KPLV 283
N VV+ITGA+SG+G E A F AKLVL GR L+ + + + +K+ KP +
Sbjct: 37 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYL 96
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
V D+ + + + + + +D+LVNNAG+ GTI T++ R+M TN GP
Sbjct: 97 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPV 156
Query: 464 YLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P +IK + G+IV +SS+ G S P AY SK A F C+ E+ +
Sbjct: 157 ALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 216
Query: 641 VNAVNPGVITTGL 679
V ++PG I T L
Sbjct: 217 VTVISPGYIHTNL 229
>AF151851-1|AAD34088.1| 291|Homo sapiens CGI-93 protein protein.
Length = 291
Score = 119 bits (286), Expect = 1e-26
Identities = 70/193 (36%), Positives = 103/193 (53%), Gaps = 4/193 (2%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKI---KPLV 283
N VV+ITGA+SG+G E A F AKLVL GR L+ + + + +K+ KP +
Sbjct: 57 NAVVVITGATSGLGKECAKVFYAAGAKLVLCGRNGGALEELIRELTASHATKVQTHKPYL 116
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
V D+ + + + + + +D+LVNNAG+ GTI T++ R+M TN GP
Sbjct: 117 VTFDLTDSGAIVAAAAEILQCFGYVDILVNNAGISYRGTIMDTTVDVDKRVMETNYFGPV 176
Query: 464 YLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P +IK + G+IV +SS+ G S P AY SK A F C+ E+ +
Sbjct: 177 ALTKALLPSMIKRRQGHIVAISSIQGKMSIPFRSAYAASKHATQAFFDCLRAEMEQYEIE 236
Query: 641 VNAVNPGVITTGL 679
V ++PG I T L
Sbjct: 237 VTVISPGYIHTNL 249
>BC036001-1|AAH36001.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 115 bits (277), Expect = 2e-25
Identities = 74/216 (34%), Positives = 111/216 (51%), Gaps = 4/216 (1%)
Frame = +2
Query: 68 NFTKLWKLLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDC 247
+F KL+ + ++V+ITGA GIG TAYEFAKL +KLVL K L+ A+ C
Sbjct: 21 SFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC 80
Query: 248 ESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQY 427
+ +K+ VV D +N D+ + KK + +LVNNAGV+ + + T Q
Sbjct: 81 KGLG-AKVHTFVV--DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQI 137
Query: 428 DRIMNTNVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ NV ++ T +P + K G+IV V+S G S P +LAYC SK A F +
Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197
Query: 605 CVALEVA---LKGVRVNAVNPGVITTGLHKKGEGSM 703
+ E+A + GV+ + P + TG K S+
Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>BC021673-1|AAH21673.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 115 bits (277), Expect = 2e-25
Identities = 74/216 (34%), Positives = 111/216 (51%), Gaps = 4/216 (1%)
Frame = +2
Query: 68 NFTKLWKLLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDC 247
+F KL+ + ++V+ITGA GIG TAYEFAKL +KLVL K L+ A+ C
Sbjct: 21 SFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC 80
Query: 248 ESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQY 427
+ +K+ VV D +N D+ + KK + +LVNNAGV+ + + T Q
Sbjct: 81 KGLG-AKVHTFVV--DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQI 137
Query: 428 DRIMNTNVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ NV ++ T +P + K G+IV V+S G S P +LAYC SK A F +
Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197
Query: 605 CVALEVA---LKGVRVNAVNPGVITTGLHKKGEGSM 703
+ E+A + GV+ + P + TG K S+
Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>BC016367-1|AAH16367.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 115 bits (277), Expect = 2e-25
Identities = 74/216 (34%), Positives = 111/216 (51%), Gaps = 4/216 (1%)
Frame = +2
Query: 68 NFTKLWKLLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDC 247
+F KL+ + ++V+ITGA GIG TAYEFAKL +KLVL K L+ A+ C
Sbjct: 21 SFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC 80
Query: 248 ESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQY 427
+ +K+ VV D +N D+ + KK + +LVNNAGV+ + + T Q
Sbjct: 81 KGLG-AKVHTFVV--DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQI 137
Query: 428 DRIMNTNVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ NV ++ T +P + K G+IV V+S G S P +LAYC SK A F +
Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197
Query: 605 CVALEVA---LKGVRVNAVNPGVITTGLHKKGEGSM 703
+ E+A + GV+ + P + TG K S+
Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>BC014327-1|AAH14327.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 11 protein.
Length = 300
Score = 115 bits (277), Expect = 2e-25
Identities = 74/216 (34%), Positives = 111/216 (51%), Gaps = 4/216 (1%)
Frame = +2
Query: 68 NFTKLWKLLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDC 247
+F KL+ + ++V+ITGA GIG TAYEFAKL +KLVL K L+ A+ C
Sbjct: 21 SFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC 80
Query: 248 ESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQY 427
+ +K+ VV D +N D+ + KK + +LVNNAGV+ + + T Q
Sbjct: 81 KGLG-AKVHTFVV--DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQI 137
Query: 428 DRIMNTNVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ NV ++ T +P + K G+IV V+S G S P +LAYC SK A F +
Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197
Query: 605 CVALEVA---LKGVRVNAVNPGVITTGLHKKGEGSM 703
+ E+A + GV+ + P + TG K S+
Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>BC007337-1|AAH07337.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 115 bits (277), Expect = 2e-25
Identities = 66/190 (34%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV-AD 295
VV +TGASSGIG E AY+ +KL LVL+ R+ L+ V C K K ++V+ D
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 111
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + E K + + ++D+LVNN G+ + TSL Y +++ N G LT
Sbjct: 112 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 171
Query: 476 LAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNA 649
+PH+I+ K G IV V+S+ G+ S P + YC SK A+ F + E+A G+ V+
Sbjct: 172 CVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSN 231
Query: 650 VNPGVITTGL 679
+ PG + + +
Sbjct: 232 ICPGPVQSNI 241
>BC000637-1|AAH00637.1| 339|Homo sapiens dehydrogenase/reductase
(SDR family) member 7 protein.
Length = 339
Score = 115 bits (277), Expect = 2e-25
Identities = 66/190 (34%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV-AD 295
VV +TGASSGIG E AY+ +KL LVL+ R+ L+ V C K K ++V+ D
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 111
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + E K + + ++D+LVNN G+ + TSL Y +++ N G LT
Sbjct: 112 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 171
Query: 476 LAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNA 649
+PH+I+ K G IV V+S+ G+ S P + YC SK A+ F + E+A G+ V+
Sbjct: 172 CVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSN 231
Query: 650 VNPGVITTGL 679
+ PG + + +
Sbjct: 232 ICPGPVQSNI 241
>AY359031-1|AAQ89390.1| 289|Homo sapiens oxidoreductase/S-2 H
protein.
Length = 289
Score = 115 bits (277), Expect = 2e-25
Identities = 66/190 (34%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV-AD 295
VV +TGASSGIG E AY+ +KL LVL+ R+ L+ V C K K ++V+ D
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 61
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + E K + + ++D+LVNN G+ + TSL Y +++ N G LT
Sbjct: 62 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 121
Query: 476 LAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNA 649
+PH+I+ K G IV V+S+ G+ S P + YC SK A+ F + E+A G+ V+
Sbjct: 122 CVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSN 181
Query: 650 VNPGVITTGL 679
+ PG + + +
Sbjct: 182 ICPGPVQSNI 191
>AY358553-1|AAQ88917.1| 300|Homo sapiens KFLL207 protein.
Length = 300
Score = 115 bits (277), Expect = 2e-25
Identities = 74/216 (34%), Positives = 111/216 (51%), Gaps = 4/216 (1%)
Frame = +2
Query: 68 NFTKLWKLLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDC 247
+F KL+ + ++V+ITGA GIG TAYEFAKL +KLVL K L+ A+ C
Sbjct: 21 SFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC 80
Query: 248 ESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQY 427
+ +K+ VV D +N D+ + KK + +LVNNAGV+ + + T Q
Sbjct: 81 KGLG-AKVHTFVV--DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQI 137
Query: 428 DRIMNTNVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ NV ++ T +P + K G+IV V+S G S P +LAYC SK A F +
Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197
Query: 605 CVALEVA---LKGVRVNAVNPGVITTGLHKKGEGSM 703
+ E+A + GV+ + P + TG K S+
Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>AF273056-1|AAM44459.1| 300|Homo sapiens CTCL tumor antigen
HD-CL-03 protein.
Length = 300
Score = 115 bits (277), Expect = 2e-25
Identities = 74/216 (34%), Positives = 111/216 (51%), Gaps = 4/216 (1%)
Frame = +2
Query: 68 NFTKLWKLLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDC 247
+F KL+ + ++V+ITGA GIG TAYEFAKL +KLVL K L+ A+ C
Sbjct: 21 SFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC 80
Query: 248 ESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQY 427
+ +K+ VV D +N D+ + KK + +LVNNAGV+ + + T Q
Sbjct: 81 KGLG-AKVHTFVV--DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQI 137
Query: 428 DRIMNTNVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ NV ++ T +P + K G+IV V+S G S P +LAYC SK A F +
Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197
Query: 605 CVALEVA---LKGVRVNAVNPGVITTGLHKKGEGSM 703
+ E+A + GV+ + P + TG K S+
Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>AF151844-1|AAD34081.1| 339|Homo sapiens CGI-86 protein protein.
Length = 339
Score = 115 bits (277), Expect = 2e-25
Identities = 66/190 (34%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV-AD 295
VV +TGASSGIG E AY+ +KL LVL+ R+ L+ V C K K ++V+ D
Sbjct: 52 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 111
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + E K + + ++D+LVNN G+ + TSL Y +++ N G LT
Sbjct: 112 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 171
Query: 476 LAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNA 649
+PH+I+ K G IV V+S+ G+ S P + YC SK A+ F + E+A G+ V+
Sbjct: 172 CVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSN 231
Query: 650 VNPGVITTGL 679
+ PG + + +
Sbjct: 232 ICPGPVQSNI 241
>AF126782-1|AAF06941.1| 289|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR4 protein.
Length = 289
Score = 115 bits (277), Expect = 2e-25
Identities = 66/190 (34%), Positives = 103/190 (54%), Gaps = 3/190 (1%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV-AD 295
VV +TGASSGIG E AY+ +KL LVL+ R+ L+ V C K K ++V+ D
Sbjct: 2 VVWVTGASSGIGEELAYQLSKLGVSLVLSARRVHELERVKRRCLENGNLKEKDILVLPLD 61
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + E K + + ++D+LVNN G+ + TSL Y +++ N G LT
Sbjct: 62 LTDTGSHEAATKAVLQEFGRIDILVNNGGMSQRSLCMDTSLDVYRKLIELNYLGTVSLTK 121
Query: 476 LAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNA 649
+PH+I+ K G IV V+S+ G+ S P + YC SK A+ F + E+A G+ V+
Sbjct: 122 CVLPHMIERKQGKIVTVNSILGIISVPLSIGYCASKHALRGFFNGLRTELATYPGIIVSN 181
Query: 650 VNPGVITTGL 679
+ PG + + +
Sbjct: 182 ICPGPVQSNI 191
>AF126780-1|AAF06939.1| 300|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR2 protein.
Length = 300
Score = 115 bits (277), Expect = 2e-25
Identities = 74/216 (34%), Positives = 111/216 (51%), Gaps = 4/216 (1%)
Frame = +2
Query: 68 NFTKLWKLLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDC 247
+F KL+ + ++V+ITGA GIG TAYEFAKL +KLVL K L+ A+ C
Sbjct: 21 SFVKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC 80
Query: 248 ESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQY 427
+ +K+ VV D +N D+ + KK + +LVNNAGV+ + + T Q
Sbjct: 81 KGLG-AKVHTFVV--DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQI 137
Query: 428 DRIMNTNVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ NV ++ T +P + K G+IV V+S G S P +LAYC SK A F +
Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197
Query: 605 CVALEVA---LKGVRVNAVNPGVITTGLHKKGEGSM 703
+ E+A + GV+ + P + TG K S+
Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>BC008650-1|AAH08650.1| 300|Homo sapiens HSD17B11 protein protein.
Length = 300
Score = 114 bits (274), Expect = 4e-25
Identities = 74/216 (34%), Positives = 111/216 (51%), Gaps = 4/216 (1%)
Frame = +2
Query: 68 NFTKLWKLLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDC 247
+F KL+ + ++V+ITGA GIG TAYEFAKL +KLVL K L+ A+ C
Sbjct: 21 SFEKLFIPKRRKSVTGEIVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC 80
Query: 248 ESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQY 427
+ +K+ VV D +N D+ + K + +LVNNAGV+ + + T Q
Sbjct: 81 KGLG-AKVHTFVV--DCSNREDIYSSAKNCKAEIGDVSILVNNAGVVYTSDLFATQDPQI 137
Query: 428 DRIMNTNVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ NV ++ T +P + K G+IV V+S G S P +LAYC SK A F +
Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197
Query: 605 CVALEVA---LKGVRVNAVNPGVITTGLHKKGEGSM 703
+ E+A + GV+ + P + TG KK S+
Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNTGFIKKMSTSL 233
>AK075348-1|BAC11560.1| 300|Homo sapiens protein ( Homo sapiens
cDNA PSEC0029 fis, clone NT2RP1000544, highly similar to
Retinal short-chain dehydrogenase/reductase 2. ).
Length = 300
Score = 114 bits (274), Expect = 4e-25
Identities = 74/216 (34%), Positives = 110/216 (50%), Gaps = 4/216 (1%)
Frame = +2
Query: 68 NFTKLWKLLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDC 247
+F KL+ + + V+ITGA GIG TAYEFAKL +KLVL K L+ A+ C
Sbjct: 21 SFVKLFIPKRRKSVTGETVLITGAGHGIGRLTAYEFAKLKSKLVLWDINKHGLEETAAKC 80
Query: 248 ESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQY 427
+ +K+ VV D +N D+ + KK + +LVNNAGV+ + + T Q
Sbjct: 81 KGLG-AKVHTFVV--DCSNREDIYSSAKKVKAEIGDVSILVNNAGVVYTSDLFATQDPQI 137
Query: 428 DRIMNTNVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ NV ++ T +P + K G+IV V+S G S P +LAYC SK A F +
Sbjct: 138 EKTFEVNVLAHFWTTKAFLPAMTKNNHGHIVTVASAAGHVSVPFLLAYCSSKFAAVGFHK 197
Query: 605 CVALEVA---LKGVRVNAVNPGVITTGLHKKGEGSM 703
+ E+A + GV+ + P + TG K S+
Sbjct: 198 TLTDELAALQITGVKTTCLCPNFVNTGFIKNPSTSL 233
>BC006294-1|AAH06294.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 112 bits (270), Expect = 1e-24
Identities = 62/192 (32%), Positives = 105/192 (54%), Gaps = 1/192 (0%)
Frame = +2
Query: 107 FANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVV 286
+A KVV++TG GIGA F A++V+ + + E + P + +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG----GRALEQELPGAV---FI 59
Query: 287 VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPY 463
+ D+ E DV+ ++ +T+ + +LD +VNNAG E TS + +++ N+ G Y
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 464 YLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
LT LA+P+L K++GN++N+SS+ G + Y +K A+ T+ +AL+ + GVRV
Sbjct: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179
Query: 644 NAVNPGVITTGL 679
N ++PG I T L
Sbjct: 180 NCISPGNIWTPL 191
>BC006283-1|AAH06283.1| 270|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 14 protein.
Length = 270
Score = 112 bits (270), Expect = 1e-24
Identities = 62/192 (32%), Positives = 105/192 (54%), Gaps = 1/192 (0%)
Frame = +2
Query: 107 FANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVV 286
+A KVV++TG GIGA F A++V+ + + E + P + +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG----GRALEQELPGAV---FI 59
Query: 287 VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPY 463
+ D+ E DV+ ++ +T+ + +LD +VNNAG E TS + +++ N+ G Y
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 464 YLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
LT LA+P+L K++GN++N+SS+ G + Y +K A+ T+ +AL+ + GVRV
Sbjct: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179
Query: 644 NAVNPGVITTGL 679
N ++PG I T L
Sbjct: 180 NCISPGNIWTPL 191
>AY358430-1|AAQ88796.1| 270|Homo sapiens ATGT502 protein.
Length = 270
Score = 112 bits (270), Expect = 1e-24
Identities = 62/192 (32%), Positives = 105/192 (54%), Gaps = 1/192 (0%)
Frame = +2
Query: 107 FANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVV 286
+A KVV++TG GIGA F A++V+ + + E + P + +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG----GRALEQELPGAV---FI 59
Query: 287 VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPY 463
+ D+ E DV+ ++ +T+ + +LD +VNNAG E TS + +++ N+ G Y
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 464 YLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
LT LA+P+L K++GN++N+SS+ G + Y +K A+ T+ +AL+ + GVRV
Sbjct: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179
Query: 644 NAVNPGVITTGL 679
N ++PG I T L
Sbjct: 180 NCISPGNIWTPL 191
>AF126781-1|AAF06940.1| 270|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR3 protein.
Length = 270
Score = 112 bits (270), Expect = 1e-24
Identities = 62/192 (32%), Positives = 105/192 (54%), Gaps = 1/192 (0%)
Frame = +2
Query: 107 FANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVV 286
+A KVV++TG GIGA F A++V+ + + E + P + +
Sbjct: 7 YAGKVVVVTGGGRGIGAGIVRAFVNSGARVVICDKDESG----GRALEQELPGAV---FI 59
Query: 287 VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPY 463
+ D+ E DV+ ++ +T+ + +LD +VNNAG E TS + +++ N+ G Y
Sbjct: 60 LCDVTQEDDVKTLVSETIRRFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTY 119
Query: 464 YLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
LT LA+P+L K++GN++N+SS+ G + Y +K A+ T+ +AL+ + GVRV
Sbjct: 120 TLTKLALPYLRKSQGNVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRV 179
Query: 644 NAVNPGVITTGL 679
N ++PG I T L
Sbjct: 180 NCISPGNIWTPL 191
>AK222857-1|BAD96577.1| 280|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 280
Score = 111 bits (266), Expect = 4e-24
Identities = 72/225 (32%), Positives = 121/225 (53%), Gaps = 1/225 (0%)
Frame = +2
Query: 104 MFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLV 283
+ AN+V ++TG++SGIG A A+ A +V++ RK++N+D + + + S
Sbjct: 33 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAG--- 89
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
+V + D E ++ K +++ +D LV +AGV G+ TS +D+I++ NV+ P
Sbjct: 90 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSP 149
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
L +P++ +G ++ VSSV + Y +SK+A+ TR +ALE+A K +R
Sbjct: 150 APLLSQLLPYMENRRGAVILVSSVAAYNPVVALGVYSVSKTALLGLTRTLALELAPKDIR 209
Query: 641 VNAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGDA 775
VN V PG+I T K G NE ++ F E H L R G++
Sbjct: 210 VNCVVPGIIKTDFSKVFHG--NESLWKNF----KEHHQLQRIGES 248
>U31875-1|AAA82048.1| 280|Homo sapiens Hep27 protein protein.
Length = 280
Score = 110 bits (265), Expect = 5e-24
Identities = 71/225 (31%), Positives = 121/225 (53%), Gaps = 1/225 (0%)
Frame = +2
Query: 104 MFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLV 283
+ AN+V ++TG++SGIG A A+ A +V++ RK++N+D + + + S
Sbjct: 33 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAG--- 89
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
+V + D E ++ K +++ +D LV +AGV G+ TS +D+I++ NV+ P
Sbjct: 90 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSP 149
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
L +P++ +G ++ VSS+ + Y +SK+A+ TR +ALE+A K +R
Sbjct: 150 ALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIR 209
Query: 641 VNAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGDA 775
VN V PG+I T K G NE ++ F E H L R G++
Sbjct: 210 VNCVVPGIIKTDFSKVFHG--NESLWKNF----KEHHQLQRIGES 248
>BC007339-1|AAH07339.2| 271|Homo sapiens DHRS2 protein protein.
Length = 271
Score = 110 bits (265), Expect = 5e-24
Identities = 71/225 (31%), Positives = 121/225 (53%), Gaps = 1/225 (0%)
Frame = +2
Query: 104 MFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLV 283
+ AN+V ++TG++SGIG A A+ A +V++ RK++N+D + + + S
Sbjct: 24 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAG--- 80
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
+V + D E ++ K +++ +D LV +AGV G+ TS +D+I++ NV+ P
Sbjct: 81 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSP 140
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
L +P++ +G ++ VSS+ + Y +SK+A+ TR +ALE+A K +R
Sbjct: 141 ALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIR 200
Query: 641 VNAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGDA 775
VN V PG+I T K G NE ++ F E H L R G++
Sbjct: 201 VNCVVPGIIKTDFSKVFHG--NESLWKNF----KEHHQLQRIGES 239
>AF244132-1|AAG33703.1| 280|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 280
Score = 110 bits (265), Expect = 5e-24
Identities = 71/225 (31%), Positives = 121/225 (53%), Gaps = 1/225 (0%)
Frame = +2
Query: 104 MFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLV 283
+ AN+V ++TG++SGIG A A+ A +V++ RK++N+D + + + S
Sbjct: 33 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAG--- 89
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
+V + D E ++ K +++ +D LV +AGV G+ TS +D+I++ NV+ P
Sbjct: 90 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSP 149
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
L +P++ +G ++ VSS+ + Y +SK+A+ TR +ALE+A K +R
Sbjct: 150 ALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIR 209
Query: 641 VNAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGDA 775
VN V PG+I T K G NE ++ F E H L R G++
Sbjct: 210 VNCVVPGIIKTDFSKVFHG--NESLWKNF----KEHHQLQRIGES 248
>BC002786-1|AAH02786.1| 300|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 protein.
Length = 300
Score = 107 bits (256), Expect = 6e-23
Identities = 62/195 (31%), Positives = 108/195 (55%), Gaps = 1/195 (0%)
Frame = +2
Query: 104 MFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLV 283
+ AN+V ++TG++SGIG A A+ A +V++ RK++N+D + + + S
Sbjct: 33 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEGLSVAG--- 89
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
+V + D E ++ K +++ +D LV +AGV G+ TS +D+I++ NV+ P
Sbjct: 90 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGVNPLVGSTLGTSEQIWDKILSVNVKSP 149
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
L +P++ +G ++ VSS+ + Y +SK+A+ TR +ALE+A K +R
Sbjct: 150 ALLLSQLLPYMENRRGAVILVSSIAAYNPVVALGVYNVSKTALLGLTRTLALELAPKDIR 209
Query: 641 VNAVNPGVITTGLHK 685
VN V PG+I T K
Sbjct: 210 VNCVVPGIIKTDFSK 224
>BC002529-1|AAH02529.1| 303|Homo sapiens peroxisomal
trans-2-enoyl-CoA reductase protein.
Length = 303
Score = 103 bits (248), Expect = 5e-22
Identities = 60/218 (27%), Positives = 109/218 (50%), Gaps = 3/218 (1%)
Frame = +2
Query: 92 LCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSP--S 265
L + +V I+TG ++GIG E +L + +V+ RK E L + A + ++ P
Sbjct: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70
Query: 266 KIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNT 445
+ + + + ++ NE +V N++K T+D + +++ LVNN G E S + ++ T
Sbjct: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130
Query: 446 NVRGPYYLTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV 622
N+ G +Y+ +K G +IVN+ T FP + +++ + T+ +ALE
Sbjct: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKA-GFPLAVHSGAARAGVYNLTKSLALEW 189
Query: 623 ALKGVRVNAVNPGVITTGLHKKGEGSMNEEQYEAFLAK 736
A G+R+N V PGVI + + GS + +E K
Sbjct: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQK 227
>AF232009-1|AAF69798.1| 303|Homo sapiens peroxisomal trans 2-enoyl
CoA reductase protein.
Length = 303
Score = 103 bits (248), Expect = 5e-22
Identities = 60/218 (27%), Positives = 109/218 (50%), Gaps = 3/218 (1%)
Frame = +2
Query: 92 LCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSP--S 265
L + +V I+TG ++GIG E +L + +V+ RK E L + A + ++ P
Sbjct: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70
Query: 266 KIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNT 445
+ + + + ++ NE +V N++K T+D + +++ LVNN G E S + ++ T
Sbjct: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130
Query: 446 NVRGPYYLTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV 622
N+ G +Y+ +K G +IVN+ T FP + +++ + T+ +ALE
Sbjct: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKA-GFPLAVHSGAARAGVYNLTKSLALEW 189
Query: 623 ALKGVRVNAVNPGVITTGLHKKGEGSMNEEQYEAFLAK 736
A G+R+N V PGVI + + GS + +E K
Sbjct: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQK 227
>AF212234-1|AAK14920.1| 322|Homo sapiens HPDHase protein.
Length = 322
Score = 103 bits (248), Expect = 5e-22
Identities = 60/218 (27%), Positives = 109/218 (50%), Gaps = 3/218 (1%)
Frame = +2
Query: 92 LCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSP--S 265
L + +V I+TG ++GIG E +L + +V+ RK E L + A + ++ P
Sbjct: 30 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 89
Query: 266 KIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNT 445
+ + + + ++ NE +V N++K T+D + +++ LVNN G E S + ++ T
Sbjct: 90 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 149
Query: 446 NVRGPYYLTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV 622
N+ G +Y+ +K G +IVN+ T FP + +++ + T+ +ALE
Sbjct: 150 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKA-GFPLAVHSGAARAGVYNLTKSLALEW 208
Query: 623 ALKGVRVNAVNPGVITTGLHKKGEGSMNEEQYEAFLAK 736
A G+R+N V PGVI + + GS + +E K
Sbjct: 209 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQK 246
>AC010686-2|AAY14657.1| 303|Homo sapiens unknown protein.
Length = 303
Score = 103 bits (248), Expect = 5e-22
Identities = 60/218 (27%), Positives = 109/218 (50%), Gaps = 3/218 (1%)
Frame = +2
Query: 92 LCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSP--S 265
L + +V I+TG ++GIG E +L + +V+ RK E L + A + ++ P
Sbjct: 11 LAPGLLQGQVAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70
Query: 266 KIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNT 445
+ + + + ++ NE +V N++K T+D + +++ LVNN G E S + ++ T
Sbjct: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLET 130
Query: 446 NVRGPYYLTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV 622
N+ G +Y+ +K G +IVN+ T FP + +++ + T+ +ALE
Sbjct: 131 NLTGTFYMCKAVYSSWMKEHGGSIVNIIVPTKA-GFPLAVHSGAARAGVYNLTKSLALEW 189
Query: 623 ALKGVRVNAVNPGVITTGLHKKGEGSMNEEQYEAFLAK 736
A G+R+N V PGVI + + GS + +E K
Sbjct: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQK 227
>AJ250303-1|CAB89810.1| 303|Homo sapiens peroxisomal 2-enoyl-CoA
reductase protein.
Length = 303
Score = 102 bits (244), Expect = 2e-21
Identities = 59/218 (27%), Positives = 108/218 (49%), Gaps = 3/218 (1%)
Frame = +2
Query: 92 LCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSP--S 265
L + +V +TG ++GIG E +L + +V+ RK E L + A + ++ P
Sbjct: 11 LAPGLLQGQVAFVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTK 70
Query: 266 KIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNT 445
+ + + + ++ NE +V N++K T+D + +++ LVNN G E S + ++ T
Sbjct: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFGKINFLVNNGGGQFLSPAEHISSKGWHAVLRT 130
Query: 446 NVRGPYYLTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV 622
N+ G +Y+ +K G +IVN+ T FP + +++ + T+ +ALE
Sbjct: 131 NLTGSFYMCKAVYSSWMKEHGGSIVNIIVPTKA-GFPLAVHSGAARAGVYNLTKSLALEW 189
Query: 623 ALKGVRVNAVNPGVITTGLHKKGEGSMNEEQYEAFLAK 736
A G+R+N V PGVI + + GS + +E K
Sbjct: 190 ACSGIRINCVAPGVIYSQTAVENYGSWGQSFFEGSFQK 227
>DQ344810-1|ABD75823.1| 278|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase short isoform protein.
Length = 278
Score = 99 bits (238), Expect = 9e-21
Identities = 64/223 (28%), Positives = 116/223 (52%), Gaps = 2/223 (0%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
ANKV ++T ++ GIG A A+ A +V++ RK++N+D + + + S V
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTG---TV 87
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGPYY 466
+ D E ++ V + +D+LV+NA V G+I + +D+ ++ NV+ P
Sbjct: 88 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 147
Query: 467 LTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
+T +P + K G ++V VSS+ P Y +SK+A+ T+ +A+E+A + +RV
Sbjct: 148 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 207
Query: 644 NAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGD 772
N + PG+I T + M++E+ E+ + + LG P D
Sbjct: 208 NCLAPGLIKTSFSRM--LWMDKEKEES-MKETLRIRRLGEPED 247
>BC003019-1|AAH03019.1| 278|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 protein.
Length = 278
Score = 99 bits (238), Expect = 9e-21
Identities = 64/223 (28%), Positives = 116/223 (52%), Gaps = 2/223 (0%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
ANKV ++T ++ GIG A A+ A +V++ RK++N+D + + + S V
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTG---TV 87
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGPYY 466
+ D E ++ V + +D+LV+NA V G+I + +D+ ++ NV+ P
Sbjct: 88 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 147
Query: 467 LTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
+T +P + K G ++V VSS+ P Y +SK+A+ T+ +A+E+A + +RV
Sbjct: 148 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 207
Query: 644 NAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGD 772
N + PG+I T + M++E+ E+ + + LG P D
Sbjct: 208 NCLAPGLIKTSFSRM--LWMDKEKEES-MKETLRIRRLGEPED 247
>AY358638-1|AAQ89001.1| 278|Homo sapiens SCAD-SRL protein.
Length = 278
Score = 99 bits (238), Expect = 9e-21
Identities = 64/223 (28%), Positives = 116/223 (52%), Gaps = 2/223 (0%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
ANKV ++T ++ GIG A A+ A +V++ RK++N+D + + + S V
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTG---TV 87
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGPYY 466
+ D E ++ V + +D+LV+NA V G+I + +D+ ++ NV+ P
Sbjct: 88 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 147
Query: 467 LTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
+T +P + K G ++V VSS+ P Y +SK+A+ T+ +A+E+A + +RV
Sbjct: 148 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 207
Query: 644 NAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGD 772
N + PG+I T + M++E+ E+ + + LG P D
Sbjct: 208 NCLAPGLIKTSFSRM--LWMDKEKEES-MKETLRIRRLGEPED 247
>AF064256-1|AAQ13444.1| 278|Homo sapiens Hep27-like protein
protein.
Length = 278
Score = 99 bits (238), Expect = 9e-21
Identities = 64/223 (28%), Positives = 117/223 (52%), Gaps = 2/223 (0%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
ANKV ++T ++ GIG A A+ A +V++ RK++N+D + + + S + +V
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGTVCMV 90
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGPYY 466
D E ++ V + +D+LV+NA V G+I + +D+ ++ NV+ P
Sbjct: 91 G---KAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 147
Query: 467 LTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
+T +P + K G ++V VSS+ P Y +SK+A+ T+ +A+E+A + +RV
Sbjct: 148 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 207
Query: 644 NAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGD 772
N + PG+I T + M++E+ E+ + + LG P D
Sbjct: 208 NCLAPGLIKTSFSRM--LWMDKEKEES-MKETLRIRRLGEPED 247
>AB045131-1|BAB18775.1| 260|Homo sapiens NADPH-dependent retinol
dehydrogenase/reductase protein.
Length = 260
Score = 99 bits (238), Expect = 9e-21
Identities = 64/223 (28%), Positives = 116/223 (52%), Gaps = 2/223 (0%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
ANKV ++T ++ GIG A A+ A +V++ RK++N+D + + + S V
Sbjct: 13 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTG---TV 69
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGPYY 466
+ D E ++ V + +D+LV+NA V G+I + +D+ ++ NV+ P
Sbjct: 70 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 129
Query: 467 LTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
+T +P + K G ++V VSS+ P Y +SK+A+ T+ +A+E+A + +RV
Sbjct: 130 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 189
Query: 644 NAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGD 772
N + PG+I T + M++E+ E+ + + LG P D
Sbjct: 190 NCLAPGLIKTSFSRM--LWMDKEKEES-MKETLRIRRLGEPED 229
>AF044127-1|AAD02292.1| 260|Homo sapiens peroxisomal short-chain
alcohol dehydrogenase protein.
Length = 260
Score = 99.1 bits (236), Expect = 2e-20
Identities = 63/223 (28%), Positives = 116/223 (52%), Gaps = 2/223 (0%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
ANKV ++T ++ GIG A A+ A +V++ RK++N+D + + + S V
Sbjct: 13 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTG---TV 69
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGPYY 466
+ D E ++ V + +D+LV+NA V G++ + +D+ ++ NV+ P
Sbjct: 70 CHVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPAL 129
Query: 467 LTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
+T +P + K G ++V VSS+ P Y +SK+A+ T+ +A+E+A + +RV
Sbjct: 130 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 189
Query: 644 NAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGD 772
N + PG+I T + M++E+ E+ + + LG P D
Sbjct: 190 NCLAPGLIKTSFSRM--LWMDKEKEES-MKETLRIRRLGEPED 229
>AK001870-1|BAA91953.1| 278|Homo sapiens protein ( Homo sapiens
cDNA FLJ11008 fis, clone PLACE1003100, moderately
similar to HEP27 PROTEIN. ).
Length = 278
Score = 98.3 bits (234), Expect = 3e-20
Identities = 64/223 (28%), Positives = 115/223 (51%), Gaps = 2/223 (0%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
ANKV + T ++ GIG A A+ A +V++ RK++N+D + + + S V
Sbjct: 31 ANKVALATASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTG---TV 87
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRGPYY 466
+ D E ++ V + +D+LV+NA V G+I + +D+ ++ NV+ P
Sbjct: 88 CHVGKAEDRERLVATAVKLHGGIDILVSNAAVNPFFGSIMDVTEEVWDKTLDINVKAPAL 147
Query: 467 LTMLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
+T +P + K G ++V VSS+ P Y +SK+A+ T+ +A+E+A + +RV
Sbjct: 148 MTKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRV 207
Query: 644 NAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHALGRPGD 772
N + PG+I T + M++E+ E+ + + LG P D
Sbjct: 208 NCLAPGLIKTSFSRM--LWMDKEKEES-MKETLRIRRLGEPED 247
>BC112305-1|AAI12306.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 96.7 bits (230), Expect = 8e-20
Identities = 57/196 (29%), Positives = 99/196 (50%), Gaps = 4/196 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A ++V+ITGA GIG +T YEFAK + LVL K ++ A++C + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D +N ++ + + + ++VNNAG + + +T + + N+ G +++
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 470 TMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV-AL--KGV 637
T +P ++ + G+IV V+SV G P ++ YC SK A F R + E+ AL G+
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 638 RVNAVNPGVITTGLHK 685
+ + + P + TG K
Sbjct: 212 KTSCLCPVFVNTGFTK 227
>BC112303-1|AAI12304.1| 300|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 13 protein.
Length = 300
Score = 96.7 bits (230), Expect = 8e-20
Identities = 57/196 (29%), Positives = 99/196 (50%), Gaps = 4/196 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A ++V+ITGA GIG +T YEFAK + LVL K ++ A++C + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D +N ++ + + + ++VNNAG + + +T + + N+ G +++
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 470 TMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV-AL--KGV 637
T +P ++ + G+IV V+SV G P ++ YC SK A F R + E+ AL G+
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 638 RVNAVNPGVITTGLHK 685
+ + + P + TG K
Sbjct: 212 KTSCLCPVFVNTGFTK 227
>AY358575-1|AAQ88938.1| 300|Homo sapiens NIIL497 protein.
Length = 300
Score = 96.7 bits (230), Expect = 8e-20
Identities = 57/196 (29%), Positives = 99/196 (50%), Gaps = 4/196 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A ++V+ITGA GIG +T YEFAK + LVL K ++ A++C + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D +N ++ + + + ++VNNAG + + +T + + N+ G +++
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 470 TMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV-AL--KGV 637
T +P ++ + G+IV V+SV G P ++ YC SK A F R + E+ AL G+
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 638 RVNAVNPGVITTGLHK 685
+ + + P + TG K
Sbjct: 212 KTSCLCPVFVNTGFTK 227
>AY268355-1|AAP42289.1| 300|Homo sapiens short-chain
dehydrogenase/reductase 9 protein.
Length = 300
Score = 96.7 bits (230), Expect = 8e-20
Identities = 57/196 (29%), Positives = 99/196 (50%), Gaps = 4/196 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A ++V+ITGA GIG +T YEFAK + LVL K ++ A++C + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D +N ++ + + + ++VNNAG + + +T + + N+ G +++
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 470 TMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV-AL--KGV 637
T +P ++ + G+IV V+SV G P ++ YC SK A F R + E+ AL G+
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 638 RVNAVNPGVITTGLHK 685
+ + + P + TG K
Sbjct: 212 KTSCLCPVFVNTGFTK 227
>AY186249-1|AAO72313.1| 300|Homo sapiens 17-beta hydroxysteroid
dehydrogenase protein.
Length = 300
Score = 96.7 bits (230), Expect = 8e-20
Identities = 57/196 (29%), Positives = 99/196 (50%), Gaps = 4/196 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A ++V+ITGA GIG +T YEFAK + LVL K ++ A++C + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D +N ++ + + + ++VNNAG + + +T + + N+ G +++
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 470 TMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV-AL--KGV 637
T +P ++ + G+IV V+SV G P ++ YC SK A F R + E+ AL G+
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 638 RVNAVNPGVITTGLHK 685
+ + + P + TG K
Sbjct: 212 KTSCLCPVFVNTGFTK 227
>AB073347-1|BAD38632.1| 300|Homo sapiens putative protein product
of HMFN0376 protein.
Length = 300
Score = 96.7 bits (230), Expect = 8e-20
Identities = 57/196 (29%), Positives = 99/196 (50%), Gaps = 4/196 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A ++V+ITGA GIG +T YEFAK + LVL K ++ A++C + V
Sbjct: 35 AGEIVLITGAGHGIGRQTTYEFAKRQSILVLWDINKRGVEETAAECRKLG---VTAHAYV 91
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D +N ++ + + + ++VNNAG + + +T + + N+ G +++
Sbjct: 92 VDCSNREEIYRSLNQVKKEVGDVTIVVNNAGTVYPADLLSTKDEEITKTFEVNILGHFWI 151
Query: 470 TMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV-AL--KGV 637
T +P ++ + G+IV V+SV G P ++ YC SK A F R + E+ AL G+
Sbjct: 152 TKALLPSMMERNHGHIVTVASVCGHEGIPYLIPYCSSKFAAVGFHRGLTSELQALGKTGI 211
Query: 638 RVNAVNPGVITTGLHK 685
+ + + P + TG K
Sbjct: 212 KTSCLCPVFVNTGFTK 227
>BC012043-1|AAH12043.1| 312|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 12 protein.
Length = 312
Score = 94.3 bits (224), Expect = 4e-19
Identities = 62/216 (28%), Positives = 113/216 (52%), Gaps = 5/216 (2%)
Frame = +2
Query: 125 IITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMNN 304
++TG++ GIG A E AK K+VL R K+ LD V+S+ + + K++ + D +
Sbjct: 54 VVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKF--KVETRTIAVDFAS 111
Query: 305 ESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIM----NTNVRGPYYLT 472
E D+ + IK + ++ +LVNN G+ + D ++ N N+ +T
Sbjct: 112 E-DIYDKIKTGLAGL-EIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMT 169
Query: 473 MLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNA 649
L +P ++ ++KG I+N+SS +G+ P + Y +K+ +D F++C+ E KGV V +
Sbjct: 170 QLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQS 229
Query: 650 VNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHAL 757
V P + T L K + ++++ E F+ +T L
Sbjct: 230 VLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGL 265
>AK222881-1|BAD96601.1| 312|Homo sapiens steroid dehydrogenase
homolog protein.
Length = 312
Score = 94.3 bits (224), Expect = 4e-19
Identities = 62/216 (28%), Positives = 113/216 (52%), Gaps = 5/216 (2%)
Frame = +2
Query: 125 IITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMNN 304
++TG++ GIG A E AK K+VL R K+ LD V+S+ + + K++ + D +
Sbjct: 54 VVTGSTDGIGKSYAEELAKHGMKVVLISRSKDKLDQVSSEIKEKF--KVETRTIAVDFAS 111
Query: 305 ESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIM----NTNVRGPYYLT 472
E D+ + IK + ++ +LVNN G+ + D ++ N N+ +T
Sbjct: 112 E-DIYDKIKTGLAGL-EIGILVNNVGMSYEYPEYFLDVPDLDNVIKKMININILSVCKMT 169
Query: 473 MLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNA 649
L +P ++ ++KG I+N+SS +G+ P + Y +K+ +D F++C+ E KGV V +
Sbjct: 170 QLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQCLHEEYRSKGVFVQS 229
Query: 650 VNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHAL 757
V P + T L K + ++++ E F+ +T L
Sbjct: 230 VLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGL 265
>M76665-1|AAC31757.1| 292|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase protein.
Length = 292
Score = 92.7 bits (220), Expect = 1e-18
Identities = 60/182 (32%), Positives = 88/182 (48%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
EM K VI+TGAS GIG E AY AK+ A +V+T R KE L V S C +
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAH-- 87
Query: 281 VVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGP 460
+ M + + E + + LD+L+ N S + + + M N
Sbjct: 88 YIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSY 147
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT+ A+P L ++ G+IV VSS+ G ++P V AY SK A+D F + E ++ V
Sbjct: 148 VVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 641 VN 646
V+
Sbjct: 208 VS 209
>BC012593-1|AAH12593.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 92.7 bits (220), Expect = 1e-18
Identities = 60/182 (32%), Positives = 88/182 (48%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
EM K VI+TGAS GIG E AY AK+ A +V+T R KE L V S C +
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAH-- 87
Query: 281 VVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGP 460
+ M + + E + + LD+L+ N S + + + M N
Sbjct: 88 YIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSY 147
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT+ A+P L ++ G+IV VSS+ G ++P V AY SK A+D F + E ++ V
Sbjct: 148 VVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 641 VN 646
V+
Sbjct: 208 VS 209
>AY044084-1|AAK83653.1| 292|Homo sapiens 11-beta hydroxysteroid
dehydrogenase type 1 protein.
Length = 292
Score = 92.7 bits (220), Expect = 1e-18
Identities = 60/182 (32%), Positives = 88/182 (48%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
EM K VI+TGAS GIG E AY AK+ A +V+T R KE L V S C +
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAH-- 87
Query: 281 VVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGP 460
+ M + + E + + LD+L+ N S + + + M N
Sbjct: 88 YIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSY 147
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT+ A+P L ++ G+IV VSS+ G ++P V AY SK A+D F + E ++ V
Sbjct: 148 VVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 641 VN 646
V+
Sbjct: 208 VS 209
>AL031316-4|CAI20063.1| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 92.7 bits (220), Expect = 1e-18
Identities = 60/182 (32%), Positives = 88/182 (48%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
EM K VI+TGAS GIG E AY AK+ A +V+T R KE L V S C +
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAH-- 87
Query: 281 VVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGP 460
+ M + + E + + LD+L+ N S + + + M N
Sbjct: 88 YIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSY 147
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT+ A+P L ++ G+IV VSS+ G ++P V AY SK A+D F + E ++ V
Sbjct: 148 VVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 641 VN 646
V+
Sbjct: 208 VS 209
>AL022398-8|CAA18541.2| 292|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 1 protein.
Length = 292
Score = 92.7 bits (220), Expect = 1e-18
Identities = 60/182 (32%), Positives = 88/182 (48%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
EM K VI+TGAS GIG E AY AK+ A +V+T R KE L V S C +
Sbjct: 30 EMLQGKKVIVTGASKGIGREMAYHLAKMGAHVVVTARSKETLQKVVSHCLELGAASAH-- 87
Query: 281 VVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGP 460
+ M + + E + + LD+L+ N S + + + M N
Sbjct: 88 YIAGTMEDMTFAEQFVAQAGKLMGGLDMLILNHITNTSLNLFHDDIHHVRKSMEVNFLSY 147
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT+ A+P L ++ G+IV VSS+ G ++P V AY SK A+D F + E ++ V
Sbjct: 148 VVLTVAALPMLKQSNGSIVVVSSLAGKVAYPMVAAYSASKFALDGFFSSIRKEYSVSRVN 207
Query: 641 VN 646
V+
Sbjct: 208 VS 209
>AF139841-1|AAP97273.1| 244|Homo sapiens carbonyl reductase II
protein.
Length = 244
Score = 92.3 bits (219), Expect = 2e-18
Identities = 66/197 (33%), Positives = 99/197 (50%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMF-ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
E+F A + V++TGA GIG T A++V R + +LD++ +C P
Sbjct: 2 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP----- 56
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVR 454
V D+ + E + + + +D+LVNNA V L +E T A +DR N+R
Sbjct: 57 --VCVDLGDWEATE----RALGSVGPVDLLVNNAAVALLQPFLEVTKEA-FDRSFEVNLR 109
Query: 455 GPYYLTMLAIPHLIK--TKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
++ +A LI G IVNVSS R+ N YC +K A+D T+ +ALE+
Sbjct: 110 AVIQVSQIAARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 629 KGVRVNAVNPGVITTGL 679
+RVNAVNP V+ T +
Sbjct: 170 HKIRVNAVNPTVVMTSM 186
>BT006881-1|AAP35527.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 90.6 bits (215), Expect = 5e-18
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMF-ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
E+F A + V++TGA GIG T A++V R + +LD++ +C P
Sbjct: 2 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP----- 56
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVR 454
V D+ + E + + + +D+LVNNA V L +E T A +DR N+R
Sbjct: 57 --VCVDLGDWEATE----RALGSVGPVDLLVNNAAVALLQPFLEVTKEA-FDRSFEVNLR 109
Query: 455 GPYYLTMLAIPHLIK--TKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
++ + LI G IVNVSS R+ N YC +K A+D T+ +ALE+
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 629 KGVRVNAVNPGVITTGL 679
+RVNAVNP V+ T +
Sbjct: 170 HKIRVNAVNPTVVMTSM 186
>BC003018-1|AAH03018.1| 243|Homo sapiens Unknown (protein for
IMAGE:2822726) protein.
Length = 243
Score = 90.6 bits (215), Expect = 5e-18
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMF-ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
E+F A + V++TGA GIG T A++V R + +LD++ +C P
Sbjct: 1 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP----- 55
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVR 454
V D+ + E + + + +D+LVNNA V L +E T A +DR N+R
Sbjct: 56 --VCVDLGDWEATE----RALGSVGPVDLLVNNAAVALLQPFLEVTKEA-FDRSFEVNLR 108
Query: 455 GPYYLTMLAIPHLIK--TKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
++ + LI G IVNVSS R+ N YC +K A+D T+ +ALE+
Sbjct: 109 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 168
Query: 629 KGVRVNAVNPGVITTGL 679
+RVNAVNP V+ T +
Sbjct: 169 HKIRVNAVNPTVVMTSM 185
>BC001470-1|AAH01470.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 90.6 bits (215), Expect = 5e-18
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMF-ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
E+F A + V++TGA GIG T A++V R + +LD++ +C P
Sbjct: 2 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP----- 56
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVR 454
V D+ + E + + + +D+LVNNA V L +E T A +DR N+R
Sbjct: 57 --VCVDLGDWEATE----RALGSVGPVDLLVNNAAVALLQPFLEVTKEA-FDRSFEVNLR 109
Query: 455 GPYYLTMLAIPHLIK--TKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
++ + LI G IVNVSS R+ N YC +K A+D T+ +ALE+
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 629 KGVRVNAVNPGVITTGL 679
+RVNAVNP V+ T +
Sbjct: 170 HKIRVNAVNPTVVMTSM 186
>AF515625-1|AAM54026.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 90.6 bits (215), Expect = 5e-18
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMF-ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
E+F A + V++TGA GIG T A++V R + +LD++ +C P
Sbjct: 2 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP----- 56
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVR 454
V D+ + E + + + +D+LVNNA V L +E T A +DR N+R
Sbjct: 57 --VCVDLGDWEATE----RALGSVGPVDLLVNNAAVALLQPFLEVTKEA-FDRSFEVNLR 109
Query: 455 GPYYLTMLAIPHLIK--TKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
++ + LI G IVNVSS R+ N YC +K A+D T+ +ALE+
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 629 KGVRVNAVNPGVITTGL 679
+RVNAVNP V+ T +
Sbjct: 170 HKIRVNAVNPTVVMTSM 186
>AF515624-1|AAO15991.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 90.6 bits (215), Expect = 5e-18
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMF-ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
E+F A + V++TGA GIG T A++V R + +LD++ +C P
Sbjct: 2 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP----- 56
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVR 454
V D+ + E + + + +D+LVNNA V L +E T A +DR N+R
Sbjct: 57 --VCVDLGDWEATE----RALGSVGPVDLLVNNAAVALLQPFLEVTKEA-FDRSFEVNLR 109
Query: 455 GPYYLTMLAIPHLIK--TKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
++ + LI G IVNVSS R+ N YC +K A+D T+ +ALE+
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 629 KGVRVNAVNPGVITTGL 679
+RVNAVNP V+ T +
Sbjct: 170 HKIRVNAVNPTVVMTSM 186
>AF515623-1|AAN59786.1| 244|Homo sapiens dicarbonyl/L-xylulose
reductase protein.
Length = 244
Score = 90.6 bits (215), Expect = 5e-18
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMF-ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
E+F A + V++TGA GIG T A++V R + +LD++ +C P
Sbjct: 2 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP----- 56
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVR 454
V D+ + E + + + +D+LVNNA V L +E T A +DR N+R
Sbjct: 57 --VCVDLGDWEATE----RALGSVGPVDLLVNNAAVALLQPFLEVTKEA-FDRSFEVNLR 109
Query: 455 GPYYLTMLAIPHLIK--TKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
++ + LI G IVNVSS R+ N YC +K A+D T+ +ALE+
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 629 KGVRVNAVNPGVITTGL 679
+RVNAVNP V+ T +
Sbjct: 170 HKIRVNAVNPTVVMTSM 186
>AF113123-1|AAF14864.1| 244|Homo sapiens carbonyl reductase
protein.
Length = 244
Score = 90.6 bits (215), Expect = 5e-18
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMF-ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
E+F A + V++TGA GIG T A++V R + +LD++ +C P
Sbjct: 2 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP----- 56
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVR 454
V D+ + E + + + +D+LVNNA V L +E T A +DR N+R
Sbjct: 57 --VCVDLGDWEATE----RALGSVGPVDLLVNNAAVALLQPFLEVTKEA-FDRSFEVNLR 109
Query: 455 GPYYLTMLAIPHLIK--TKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
++ + LI G IVNVSS R+ N YC +K A+D T+ +ALE+
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 629 KGVRVNAVNPGVITTGL 679
+RVNAVNP V+ T +
Sbjct: 170 HKIRVNAVNPTVVMTSM 186
>AB013846-1|BAB64299.1| 244|Homo sapiens kidney dicarbonyl
reductase protein.
Length = 244
Score = 90.6 bits (215), Expect = 5e-18
Identities = 65/197 (32%), Positives = 98/197 (49%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMF-ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
E+F A + V++TGA GIG T A++V R + +LD++ +C P
Sbjct: 2 ELFLAGRRVLVTGAGKGIGRGTVQALHATGARVVAVSRTQADLDSLVRECPGIEP----- 56
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVR 454
V D+ + E + + + +D+LVNNA V L +E T A +DR N+R
Sbjct: 57 --VCVDLGDWEATE----RALGSVGPVDLLVNNAAVALLQPFLEVTKEA-FDRSFEVNLR 109
Query: 455 GPYYLTMLAIPHLIK--TKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
++ + LI G IVNVSS R+ N YC +K A+D T+ +ALE+
Sbjct: 110 AVIQVSQIVARGLIARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMALELGP 169
Query: 629 KGVRVNAVNPGVITTGL 679
+RVNAVNP V+ T +
Sbjct: 170 HKIRVNAVNPTVVMTSM 186
>BC019317-1|AAH19317.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 87.4 bits (207), Expect = 5e-17
Identities = 59/191 (30%), Positives = 93/191 (48%), Gaps = 4/191 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTG--RKKENLDNVASDCESQSPSKIK 274
E +K V++TG SG G A LV G K + D V + +S + +++
Sbjct: 51 EPVGSKAVLVTGCDSGFGFSLAKHLHS-KGFLVFAGCLMKDKGHDGV-KELDSLNSDRLR 108
Query: 275 P--LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTN 448
L V + E VE + D + LVNNAG+ G +E TSL Y ++ N
Sbjct: 109 TVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVN 168
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T +P + + KG +VN+SS+ G + P YCI+K ++ F+ C+ E+
Sbjct: 169 LWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYP 228
Query: 629 KGVRVNAVNPG 661
GV+V+ V PG
Sbjct: 229 LGVKVSVVEPG 239
>BC005844-1|AAH05844.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 87.4 bits (207), Expect = 5e-17
Identities = 59/191 (30%), Positives = 93/191 (48%), Gaps = 4/191 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTG--RKKENLDNVASDCESQSPSKIK 274
E +K V++TG SG G A LV G K + D V + +S + +++
Sbjct: 51 EPVGSKAVLVTGCDSGFGFSLAKHLHS-KGFLVFAGCLMKDKGHDGV-KELDSLNSDRLR 108
Query: 275 P--LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTN 448
L V + E VE + D + LVNNAG+ G +E TSL Y ++ N
Sbjct: 109 TVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVN 168
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T +P + + KG +VN+SS+ G + P YCI+K ++ F+ C+ E+
Sbjct: 169 LWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYP 228
Query: 629 KGVRVNAVNPG 661
GV+V+ V PG
Sbjct: 229 LGVKVSVVEPG 239
>DQ903072-1|ABI75347.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 87.0 bits (206), Expect = 7e-17
Identities = 63/207 (30%), Positives = 98/207 (47%), Gaps = 6/207 (2%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV ++TGA+ GIG A AK+ L E + + Q + K L + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ-KTLFIQCD 64
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ ++ + + +K VD++ +LD+LVNNAGV + +++ + N+ T
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVISGTY 116
Query: 476 LAIPHLIKTKGN----IVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL--KGV 637
L + ++ K G I+N+SS+ GL YC SK I FTR AL L GV
Sbjct: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176
Query: 638 RVNAVNPGVITTGLHKKGEGSMNEEQY 718
R+NA+ PG + T + + E N QY
Sbjct: 177 RLNAICPGFVNTAILESIEKEENMGQY 203
>BC018986-1|AAH18986.1| 266|Homo sapiens hydroxyprostaglandin
dehydrogenase 15-(NAD) protein.
Length = 266
Score = 87.0 bits (206), Expect = 7e-17
Identities = 63/207 (30%), Positives = 98/207 (47%), Gaps = 6/207 (2%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV ++TGA+ GIG A AK+ L E + + Q + K L + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ-KTLFIQCD 64
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ ++ + + +K VD++ +LD+LVNNAGV + +++ + N+ T
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVISGTY 116
Query: 476 LAIPHLIKTKGN----IVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL--KGV 637
L + ++ K G I+N+SS+ GL YC SK I FTR AL L GV
Sbjct: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGV 176
Query: 638 RVNAVNPGVITTGLHKKGEGSMNEEQY 718
R+NA+ PG + T + + E N QY
Sbjct: 177 RLNAICPGFVNTAILESIEKEENMGQY 203
>BC011964-1|AAH11964.1| 343|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 1 protein.
Length = 343
Score = 87.0 bits (206), Expect = 7e-17
Identities = 59/191 (30%), Positives = 93/191 (48%), Gaps = 4/191 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTG--RKKENLDNVASDCESQSPSKIK 274
E +K V++TG SG G A LV G K + D V + +S + +++
Sbjct: 51 EPVGSKAVLVTGCDSGFGFALAKHLHS-KGFLVFAGCLMKDKGHDGV-KELDSLNSDRLR 108
Query: 275 P--LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTN 448
L V + E VE + D + LVNNAG+ G +E TSL Y ++ N
Sbjct: 109 TVQLNVCSSEEVEKVVEIVRSSLKDPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAEVN 168
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T +P + + KG +VN+SS+ G + P YCI+K ++ F+ C+ E+
Sbjct: 169 LWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEMYP 228
Query: 629 KGVRVNAVNPG 661
GV+V+ V PG
Sbjct: 229 LGVKVSVVEPG 239
>L76465-1|AAA89175.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 86.6 bits (205), Expect = 9e-17
Identities = 65/208 (31%), Positives = 99/208 (47%), Gaps = 7/208 (3%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKE-NLDNVASDCESQSPSKIKPLVVVA 292
KV ++TGA+ GIG A AK+ L E + A+ E P K L +
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKT--LFIQC 63
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ ++ + + +K VD++ +LD+LVNNAGV + +++ + N+ T
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVISGT 115
Query: 473 MLAIPHLIKTKGN----IVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL--KG 634
L + ++ K G I+N+SS+ GL YC SK I FTR AL L G
Sbjct: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175
Query: 635 VRVNAVNPGVITTGLHKKGEGSMNEEQY 718
VR+NA+ PG + T + + E N QY
Sbjct: 176 VRLNAICPGFVNTAILESIEKEENMGQY 203
>J05594-1|AAA89174.1| 266|Homo sapiens NAD+-dependent
15-hydroxyprostaglandin dehydrogenase protein.
Length = 266
Score = 86.6 bits (205), Expect = 9e-17
Identities = 65/208 (31%), Positives = 99/208 (47%), Gaps = 7/208 (3%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKE-NLDNVASDCESQSPSKIKPLVVVA 292
KV ++TGA+ GIG A AK+ L E + A+ E P K L +
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKT--LFIQC 63
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ ++ + + +K VD++ +LD+LVNNAGV + +++ + N+ T
Sbjct: 64 DVADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNEKNWEKTLQINLVSVISGT 115
Query: 473 MLAIPHLIKTKGN----IVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL--KG 634
L + ++ K G I+N+SS+ GL YC SK I FTR AL L G
Sbjct: 116 YLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSG 175
Query: 635 VRVNAVNPGVITTGLHKKGEGSMNEEQY 718
VR+NA+ PG + T + + E N QY
Sbjct: 176 VRLNAICPGFVNTAILESIEKEENMGQY 203
>BC095414-1|AAH95414.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 86.6 bits (205), Expect = 9e-17
Identities = 60/203 (29%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV+I+T A+ GIG A FA+ AK++ T + L + Q+ V D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--------VLD 58
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + ++ + +LDVL N AG + GT+ +D MN NVR Y +
Sbjct: 59 VTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 476 LAIPHLIKTK-GNIVNVSSV-TGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNA 649
+P ++ K GNI+N+SSV + ++ N Y +K+A+ T+ VA + +G+R N
Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174
Query: 650 VNPGVI-TTGLHKKGEGSMNEEQ 715
V PG + T L ++ + N E+
Sbjct: 175 VCPGTVDTPSLQERIQARGNPEE 197
>BC001953-1|AAH01953.1| 245|Homo sapiens 3-hydroxybutyrate
dehydrogenase, type 2 protein.
Length = 245
Score = 86.6 bits (205), Expect = 9e-17
Identities = 60/203 (29%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV+I+T A+ GIG A FA+ AK++ T + L + Q+ V D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--------VLD 58
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + ++ + +LDVL N AG + GT+ +D MN NVR Y +
Sbjct: 59 VTKKKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 476 LAIPHLIKTK-GNIVNVSSV-TGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNA 649
+P ++ K GNI+N+SSV + ++ N Y +K+A+ T+ VA + +G+R N
Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174
Query: 650 VNPGVI-TTGLHKKGEGSMNEEQ 715
V PG + T L ++ + N E+
Sbjct: 175 VCPGTVDTPSLQERIQARGNPEE 197
>AF164790-1|AAF80754.1| 245|Homo sapiens oxidoreductase UCPA
protein.
Length = 245
Score = 86.6 bits (205), Expect = 9e-17
Identities = 60/203 (29%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV+I+T A+ GIG A FA+ AK++ T + L + Q+ V D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--------VLD 58
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + ++ + +LDVL N AG + GT+ +D MN NVR Y +
Sbjct: 59 VTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 476 LAIPHLIKTK-GNIVNVSSV-TGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNA 649
+P ++ K GNI+N+SSV + ++ N Y +K+A+ T+ VA + +G+R N
Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSVAADFIQQGIRCNC 174
Query: 650 VNPGVI-TTGLHKKGEGSMNEEQ 715
V PG + T L ++ + N E+
Sbjct: 175 VCPGTVDTPSLQERIQARGNPEE 197
>BC033650-1|AAH33650.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 85.4 bits (202), Expect = 2e-16
Identities = 58/192 (30%), Positives = 89/192 (46%), Gaps = 1/192 (0%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
+KV + G S GIG A A+ +L + R E A D L
Sbjct: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH------LAFSC 55
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ E DV+N ++ + +++ LVN AG+ G + T ++TN+ G
Sbjct: 56 DVAKEHDVQNTFEELEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115
Query: 473 MLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNA 649
A+ +I+ +G +IVNV S+ GL+ Y SK + F+R +A EVA K +RVN
Sbjct: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175
Query: 650 VNPGVITTGLHK 685
V PG + T + K
Sbjct: 176 VAPGFVHTDMTK 187
>BC021973-1|AAH21973.1| 237|Homo sapiens carbonyl reductase 4
protein.
Length = 237
Score = 85.4 bits (202), Expect = 2e-16
Identities = 58/192 (30%), Positives = 89/192 (46%), Gaps = 1/192 (0%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
+KV + G S GIG A A+ +L + R E A D L
Sbjct: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH------LAFSC 55
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ E DV+N ++ + +++ LVN AG+ G + T ++TN+ G
Sbjct: 56 DVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115
Query: 473 MLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNA 649
A+ +I+ +G +IVNV S+ GL+ Y SK + F+R +A EVA K +RVN
Sbjct: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175
Query: 650 VNPGVITTGLHK 685
V PG + T + K
Sbjct: 176 VAPGFVHTDMTK 187
>AY358841-1|AAQ89200.1| 245|Homo sapiens GRLD6308 protein.
Length = 245
Score = 85.4 bits (202), Expect = 2e-16
Identities = 59/203 (29%), Positives = 99/203 (48%), Gaps = 3/203 (1%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV+I+T A+ GIG A FA+ AK++ T + L + Q+ V D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--------VLD 58
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + ++ + +LDVL N AG + GT+ +D MN NVR Y +
Sbjct: 59 VTKKKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 476 LAIPHLIKTK-GNIVNVSSV-TGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNA 649
+P ++ K GNI+N+SSV + ++ N Y +K+A+ T+ +A + +G+R N
Sbjct: 115 AFLPKMLAQKSGNIINMSSVASSVKGVVNRCVYSTTKAAVIGLTKSLAADFIQQGIRCNC 174
Query: 650 VNPGVI-TTGLHKKGEGSMNEEQ 715
V PG + T L ++ + N E+
Sbjct: 175 VCPGTVDTPSLQERIQARGNPEE 197
>BC000663-1|AAH00663.2| 230|Homo sapiens dehydrogenase/reductase
(SDR family) member 4 like 2 protein.
Length = 230
Score = 85.0 bits (201), Expect = 3e-16
Identities = 49/183 (26%), Positives = 95/183 (51%), Gaps = 2/183 (1%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
NKV ++T ++ GIG A A+ A +V++ RK++N+D + + + + V
Sbjct: 30 NKVALVTASTDGIGFAIARRLAQDRAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTVC 86
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLE-SGTIETTSLAQYDRIMNTNVRGPYYL 469
+ D E ++ V + +D+LV+NA V G++ + +D+ ++ NV+ P +
Sbjct: 87 HVGKAEDRERLVAMAVKLHGGIDILVSNAAVNPFFGSLMDVTEEVWDKTLDINVKAPALM 146
Query: 470 TMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
T +P + K G++V VSS+ P Y +SK+A+ +A+E+A + +RVN
Sbjct: 147 TKAVVPEMEKRGGGSVVIVSSIAAFSPSPGFSPYNVSKTALLGLNNTLAIELAPRNIRVN 206
Query: 647 AVN 655
++
Sbjct: 207 CLH 209
>BC104218-1|AAI04219.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/189 (28%), Positives = 99/189 (52%), Gaps = 4/189 (2%)
Frame = +2
Query: 125 IITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMNN 304
+++GA+ GIG A E A ++L R +E L VA D K++ ++VAD ++
Sbjct: 71 VVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTY--KVETDIIVADFSS 128
Query: 305 ESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDR---IMNTNVRGPYYLTM 475
++ I++ + + + +LVNN GV T L++ D+ I+N N+ +
Sbjct: 129 GREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVH 186
Query: 476 LAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAV 652
+ +P ++ + KG IV +SS + + P + A+ SK+ +D F+R + E A KG+ V ++
Sbjct: 187 VVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSL 246
Query: 653 NPGVITTGL 679
P + T +
Sbjct: 247 IPFYVATSM 255
>AY028377-1|AAK16927.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/189 (28%), Positives = 99/189 (52%), Gaps = 4/189 (2%)
Frame = +2
Query: 125 IITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMNN 304
+++GA+ GIG A E A ++L R +E L VA D K++ ++VAD ++
Sbjct: 50 VVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTY--KVETDIIVADFSS 107
Query: 305 ESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDR---IMNTNVRGPYYLTM 475
++ I++ + + + +LVNN GV T L++ D+ I+N N+ +
Sbjct: 108 GREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVH 165
Query: 476 LAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAV 652
+ +P ++ + KG IV +SS + + P + A+ SK+ +D F+R + E A KG+ V ++
Sbjct: 166 VVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSL 225
Query: 653 NPGVITTGL 679
P + T +
Sbjct: 226 IPFYVATSM 234
>AK074878-1|BAC11262.1| 330|Homo sapiens protein ( Homo sapiens
cDNA FLJ90397 fis, clone NT2RP2005878, moderately
similar to PUTATIVE STEROID DEHYDROGENASE KIK-I (EC
1.1.1.-). ).
Length = 330
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/189 (28%), Positives = 99/189 (52%), Gaps = 4/189 (2%)
Frame = +2
Query: 125 IITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMNN 304
+++GA+ GIG A E A ++L R +E L VA D K++ ++VAD ++
Sbjct: 71 VVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTY--KVETDIIVADFSS 128
Query: 305 ESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDR---IMNTNVRGPYYLTM 475
++ I++ + + + +LVNN GV T L++ D+ I+N N+ +
Sbjct: 129 GREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVH 186
Query: 476 LAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAV 652
+ +P ++ + KG IV +SS + + P + A+ SK+ +D F+R + E A KG+ V ++
Sbjct: 187 VVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSL 246
Query: 653 NPGVITTGL 679
P + T +
Sbjct: 247 IPFYVATSM 255
>AF237684-1|AAK15047.1| 309|Homo sapiens steroid dehydrogenase-like
protein protein.
Length = 309
Score = 82.2 bits (194), Expect = 2e-15
Identities = 53/189 (28%), Positives = 99/189 (52%), Gaps = 4/189 (2%)
Frame = +2
Query: 125 IITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMNN 304
+++GA+ GIG A E A ++L R +E L VA D K++ ++VAD ++
Sbjct: 50 VVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTY--KVETDIIVADFSS 107
Query: 305 ESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDR---IMNTNVRGPYYLTM 475
++ I++ + + + +LVNN GV T L++ D+ I+N N+ +
Sbjct: 108 GREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVH 165
Query: 476 LAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAV 652
+ +P ++ + KG IV +SS + + P + A+ SK+ +D F+R + E A KG+ V ++
Sbjct: 166 VVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSL 225
Query: 653 NPGVITTGL 679
P + T +
Sbjct: 226 IPFYVATSM 234
>AK027337-1|BAB55045.1| 179|Homo sapiens protein ( Homo sapiens
cDNA FLJ14431 fis, clone HEMBA1006521, weakly similar to
3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE (EC
1.1.1.100). ).
Length = 179
Score = 81.8 bits (193), Expect = 2e-15
Identities = 56/184 (30%), Positives = 85/184 (46%), Gaps = 1/184 (0%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
+KV + G S GIG A A+ +L + R E A D L
Sbjct: 2 DKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDH------LAFSC 55
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ E DV+N ++ + +++ LVN AG+ G + T ++TN+ G
Sbjct: 56 DVAKEHDVQNTFEEMEKHLGRVNFLVNAAGINRDGLLVRTKTEDMVSQLHTNLLGSMLTC 115
Query: 473 MLAIPHLIKTKG-NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNA 649
A+ +I+ +G +IVNV S+ GL+ Y SK + F+R +A EVA K +RVN
Sbjct: 116 KAAMRTMIQQQGGSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNV 175
Query: 650 VNPG 661
V PG
Sbjct: 176 VAPG 179
>X63657-1|CAA45197.1| 332|Homo sapiens FVT1 protein.
Length = 332
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/182 (31%), Positives = 88/182 (48%), Gaps = 3/182 (1%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPS-KIKPLVVVADM 298
V++TG SSGIG A E K A + L R ++ L + E S + K L + D+
Sbjct: 35 VVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDV 94
Query: 299 NNE-SDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + VEN+IK+ + +D+LVN AG+ SG E ++ ++R+M+ N G Y +
Sbjct: 95 SQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSR 154
Query: 476 LAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAV 652
I + + + G IV VSS G AY SK AI + +EV V +
Sbjct: 155 AVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVA 214
Query: 653 NP 658
P
Sbjct: 215 YP 216
>M93107-1|AAA58352.1| 343|Homo sapiens (R)-3-hydroxybutyrate
dehydrogenase protein.
Length = 343
Score = 81.4 bits (192), Expect = 3e-15
Identities = 56/193 (29%), Positives = 93/193 (48%), Gaps = 6/193 (3%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTG--RKKENLDNVASDCESQSPSKIK 274
E +K V++TG SG G A LV G K + D V + +S + +++
Sbjct: 51 EPVGSKAVLVTGCDSGFGFSLAKHLHS-KGFLVFAGCLMKDKGHDGV-KELDSLNSDRLR 108
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDV----LVNNAGVLESGTIETTSLAQYDRIMN 442
V ++ +VE ++ + LVNNAG+ G +E TSL Y ++
Sbjct: 109 --TVQLNVFRSEEVEKVVGDCPFEPEGPEKGMWGLVNNAGISTFGEVEFTSLETYKQVAE 166
Query: 443 TNVRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEV 622
N+ G +T +P + + KG +VN+SS+ G + P YCI+K ++ F+ C+ E+
Sbjct: 167 VNLWGTVRMTKSFLPLIRRAKGRVVNISSMLGRMANPARSPYCITKFGVEAFSDCLRYEM 226
Query: 623 ALKGVRVNAVNPG 661
GV+V+ V PG
Sbjct: 227 YPLGVKVSVVEPG 239
>BT006782-1|AAP35428.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/182 (31%), Positives = 88/182 (48%), Gaps = 3/182 (1%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPS-KIKPLVVVADM 298
V++TG SSGIG A E K A + L R ++ L + E S + K L + D+
Sbjct: 35 VVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDV 94
Query: 299 NNE-SDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + VEN+IK+ + +D+LVN AG+ SG E ++ ++R+M+ N G Y +
Sbjct: 95 SQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSR 154
Query: 476 LAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAV 652
I + + + G IV VSS G AY SK AI + +EV V +
Sbjct: 155 AVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVA 214
Query: 653 NP 658
P
Sbjct: 215 YP 216
>BC014057-1|AAH14057.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 81.4 bits (192), Expect = 3e-15
Identities = 66/201 (32%), Positives = 103/201 (51%), Gaps = 10/201 (4%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
+V ++TGAS GIG A + K A + +TGR + L VA + +S + VV D
Sbjct: 8 QVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP---VVCD 64
Query: 296 MNNESDVENIIKKTVDNYHQ--LDVLVNN--AGV-----LESGTIETTSLAQYDRIMNTN 448
+ ES+V ++ ++ VD Q LDVLVNN AGV + T + +D I N
Sbjct: 65 SSQESEVRSLFEQ-VDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVG 123
Query: 449 VRGPYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA 625
+RG Y+ ++ ++ +G IV +SS L+ NVL Y + K+A D+ A E+
Sbjct: 124 LRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNVL-YGVGKAACDKLAADCAHELR 182
Query: 626 LKGVRVNAVNPGVITTGLHKK 688
GV ++ PG++ T L K+
Sbjct: 183 RHGVSCVSLWPGIVQTELLKE 203
>BC008797-1|AAH08797.1| 332|Homo sapiens follicular lymphoma
variant translocation 1 protein.
Length = 332
Score = 81.4 bits (192), Expect = 3e-15
Identities = 57/182 (31%), Positives = 88/182 (48%), Gaps = 3/182 (1%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPS-KIKPLVVVADM 298
V++TG SSGIG A E K A + L R ++ L + E S + K L + D+
Sbjct: 35 VVVTGGSSGIGKCIAIECYKQGAFITLVARNEDKLLQAKKEIEMHSINDKQVVLCISVDV 94
Query: 299 NNE-SDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + VEN+IK+ + +D+LVN AG+ SG E ++ ++R+M+ N G Y +
Sbjct: 95 SQDYNQVENVIKQAQEKLGPVDMLVNCAGMAVSGKFEDLEVSTFERLMSINYLGSVYPSR 154
Query: 476 LAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAV 652
I + + + G IV VSS G AY SK AI + +EV V +
Sbjct: 155 AVITTMKERRVGRIVFVSSQAGQLGLFGFTAYSASKFAIRGLAEALQMEVKPYNVYITVA 214
Query: 653 NP 658
P
Sbjct: 215 YP 216
>BC106917-1|AAI06918.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 81.0 bits (191), Expect = 4e-15
Identities = 52/189 (27%), Positives = 99/189 (52%), Gaps = 4/189 (2%)
Frame = +2
Query: 125 IITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMNN 304
+++GA+ GIG A E A ++L R +E L VA D K++ ++VAD ++
Sbjct: 71 VVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTY--KVETDIIVADFSS 128
Query: 305 ESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDR---IMNTNVRGPYYLTM 475
++ I++ + + + +LVNN GV T L++ D+ I+N N+ +
Sbjct: 129 GREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVH 186
Query: 476 LAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAV 652
+ +P ++ + KG IV +SS + + P + A+ S++ +D F+R + E A KG+ V ++
Sbjct: 187 VVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSL 246
Query: 653 NPGVITTGL 679
P + T +
Sbjct: 247 IPFYVATSM 255
>BC104219-1|AAI04220.1| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 81.0 bits (191), Expect = 4e-15
Identities = 52/189 (27%), Positives = 99/189 (52%), Gaps = 4/189 (2%)
Frame = +2
Query: 125 IITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMNN 304
+++GA+ GIG A E A ++L R +E L VA D K++ ++VAD ++
Sbjct: 71 VVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTY--KVETDIIVADFSS 128
Query: 305 ESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDR---IMNTNVRGPYYLTM 475
++ I++ + + + +LVNN GV T L++ D+ I+N N+ +
Sbjct: 129 GREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVH 186
Query: 476 LAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAV 652
+ +P ++ + KG IV +SS + + P + A+ S++ +D F+R + E A KG+ V ++
Sbjct: 187 VVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASRAYLDHFSRALQYEYASKGIFVQSL 246
Query: 653 NPGVITTGL 679
P + T +
Sbjct: 247 IPFYVATSM 255
>BC002731-1|AAH02731.2| 260|Homo sapiens short-chain
dehydrogenase/reductase protein.
Length = 260
Score = 80.6 bits (190), Expect = 6e-15
Identities = 53/199 (26%), Positives = 100/199 (50%), Gaps = 8/199 (4%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQS-PSKIKP 277
E + +++ ++TGAS GIGA A + K+V R N++ +A++C+S P + P
Sbjct: 7 ERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIP 66
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
D++NE D+ ++ + +D+ +NNAG+ T+ + S + + + N NV
Sbjct: 67 --YRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLA 124
Query: 458 PYYLTMLAIPHLIKTK---GNIVNVSSVTGLRSFPNVLA--YCISKSAIDQFTRCVALEV 622
T A + + G+I+N++S++G R P + Y +K A+ T + E+
Sbjct: 125 LSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQEL 184
Query: 623 --ALKGVRVNAVNPGVITT 673
A +R ++PGV+ T
Sbjct: 185 REAQTHIRATCISPGVVET 203
>AY358712-1|AAQ89074.1| 260|Homo sapiens ARPG836 protein.
Length = 260
Score = 80.6 bits (190), Expect = 6e-15
Identities = 53/199 (26%), Positives = 100/199 (50%), Gaps = 8/199 (4%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQS-PSKIKP 277
E + +++ ++TGAS GIGA A + K+V R N++ +A++C+S P + P
Sbjct: 7 ERWRDRLALVTGASGGIGAAVARALVQQGLKVVGCARTVGNIEELAAECKSAGYPGTLIP 66
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
D++NE D+ ++ + +D+ +NNAG+ T+ + S + + + N NV
Sbjct: 67 --YRCDLSNEEDILSMFSAIRSQHSGVDICINNAGLARPDTLLSGSTSGWKDMFNVNVLA 124
Query: 458 PYYLTMLAIPHLIKTK---GNIVNVSSVTGLRSFPNVLA--YCISKSAIDQFTRCVALEV 622
T A + + G+I+N++S++G R P + Y +K A+ T + E+
Sbjct: 125 LSICTREAYQSMKERNVDDGHIININSMSGHRVLPLSVTHFYSATKYAVTALTEGLRQEL 184
Query: 623 --ALKGVRVNAVNPGVITT 673
A +R ++PGV+ T
Sbjct: 185 REAQTHIRATCISPGVVET 203
>AY313894-1|AAP83166.1| 315|Homo sapiens short-chain
dehydrogenase/reductase 10e protein.
Length = 315
Score = 80.6 bits (190), Expect = 6e-15
Identities = 55/175 (31%), Positives = 87/175 (49%), Gaps = 1/175 (0%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMN 301
V++TGA++G+G E AY +A+L + LVLT + L V +C K+ + ADM
Sbjct: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKV--FYIAADMA 89
Query: 302 NESDVENIIKKTVDNYHQLDVLV-NNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTML 478
+ E++++ +D LD LV N+ G +GT S +M N LT
Sbjct: 90 SPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGT-RARSPQATRWLMQVNFVSYVQLTSR 148
Query: 479 AIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
A+P L +KG++V VSS+ G Y +K A+D F + E+ ++ V V
Sbjct: 149 ALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>AY268352-1|AAP42286.1| 286|Homo sapiens short-chain
dehydrogenase/reductase 10b protein.
Length = 286
Score = 80.6 bits (190), Expect = 6e-15
Identities = 55/175 (31%), Positives = 87/175 (49%), Gaps = 1/175 (0%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMN 301
V++TGA++G+G E AY +A+L + LVLT + L V +C K+ + ADM
Sbjct: 32 VLLTGANAGVGEELAYHYARLGSHLVLTAHTEALLQKVVGNCRKLGAPKV--FYIAADMA 89
Query: 302 NESDVENIIKKTVDNYHQLDVLV-NNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTML 478
+ E++++ +D LD LV N+ G +GT S +M N LT
Sbjct: 90 SPEAPESVVQFALDKLGGLDYLVLNHIGGAPAGT-RARSPQATRWLMQVNFVSYVQLTSR 148
Query: 479 AIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRV 643
A+P L +KG++V VSS+ G Y +K A+D F + E+ ++ V V
Sbjct: 149 ALPSLTDSKGSLVVVSSLLGRVPTSFSTPYSAAKFALDGFFGSLRRELDVQDVNV 203
>BC018084-1|AAH18084.2| 330|Homo sapiens hydroxysteroid
dehydrogenase like 1 protein.
Length = 330
Score = 80.2 bits (189), Expect = 8e-15
Identities = 52/189 (27%), Positives = 98/189 (51%), Gaps = 4/189 (2%)
Frame = +2
Query: 125 IITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMNN 304
+++GA+ GIG A E A ++L R +E L VA D K++ ++VAD ++
Sbjct: 71 VVSGATDGIGKAYAEELASRGLNIILISRNEEKLQVVAKDIADTY--KVETDIIVADFSS 128
Query: 305 ESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDR---IMNTNVRGPYYLTM 475
++ I++ + + + +LVNN GV T L++ D+ I+N N+ +
Sbjct: 129 GREIYLPIREALKD-KDVGILVNNVGVFYPYPQYFTQLSE-DKLWDIINVNIAAASLMVH 186
Query: 476 LAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAV 652
+ +P ++ + KG IV +SS + + P + A+ SK+ +D F+R + E A KG+ V ++
Sbjct: 187 VVLPGMVERKKGAIVTISSGSCCKPTPQLAAFSASKAYLDHFSRALQYEYASKGIFVQSL 246
Query: 653 NPGVITTGL 679
P + +
Sbjct: 247 IPFYVAASM 255
>BC095451-1|AAH95451.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 79.8 bits (188), Expect = 1e-14
Identities = 59/195 (30%), Positives = 91/195 (46%), Gaps = 8/195 (4%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKEN----LDNVASDCESQSPS 265
T A V ITGAS GIG A + AK A +V+ + + L + + E
Sbjct: 5 TGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAV 64
Query: 266 KIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNT 445
K L + D+ +E + ++K + + +D+LVNNA + T + D +MN
Sbjct: 65 GGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNV 124
Query: 446 NVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRS--FPNVLAYCISKSAIDQFTRCVAL 616
N RG Y + IP+L K+K +I+N+S L F AY I+K + + +A
Sbjct: 125 NTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAE 184
Query: 617 EVALKG-VRVNAVNP 658
E KG + VNA+ P
Sbjct: 185 E--FKGEIAVNALWP 197
>AY093428-1|AAM14670.1| 418|Homo sapiens hydroxysteroid
dehydrogenase-like protein protein.
Length = 418
Score = 79.8 bits (188), Expect = 1e-14
Identities = 59/195 (30%), Positives = 91/195 (46%), Gaps = 8/195 (4%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKEN----LDNVASDCESQSPS 265
T A V ITGAS GIG A + AK A +V+ + + L + + E
Sbjct: 5 TGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAV 64
Query: 266 KIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNT 445
K L + D+ +E + ++K + + +D+LVNNA + T + D +MN
Sbjct: 65 GGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNV 124
Query: 446 NVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRS--FPNVLAYCISKSAIDQFTRCVAL 616
N RG Y + IP+L K+K +I+N+S L F AY I+K + + +A
Sbjct: 125 NTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAE 184
Query: 617 EVALKG-VRVNAVNP 658
E KG + VNA+ P
Sbjct: 185 E--FKGEIAVNALWP 197
>AL162732-1|CAM17152.1| 418|Homo sapiens hydroxysteroid
dehydrogenase like 2 protein.
Length = 418
Score = 79.8 bits (188), Expect = 1e-14
Identities = 59/195 (30%), Positives = 91/195 (46%), Gaps = 8/195 (4%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKEN----LDNVASDCESQSPS 265
T A V ITGAS GIG A + AK A +V+ + + L + + E
Sbjct: 5 TGRLAGCTVFITGASRGIGKAIALKAAKDGANIVIAAKTAQPHPKLLGTIYTAAEEIEAV 64
Query: 266 KIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNT 445
K L + D+ +E + ++K + + +D+LVNNA + T + D +MN
Sbjct: 65 GGKALPCIVDVRDEQQISAAVEKAIKKFGGIDILVNNASAISLTNTLDTPTKRLDLMMNV 124
Query: 446 NVRGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRS--FPNVLAYCISKSAIDQFTRCVAL 616
N RG Y + IP+L K+K +I+N+S L F AY I+K + + +A
Sbjct: 125 NTRGTYLASKACIPYLKKSKVAHILNISPPLNLNPVWFKQHCAYTIAKYGMSMYVLGMAE 184
Query: 617 EVALKG-VRVNAVNP 658
E KG + VNA+ P
Sbjct: 185 E--FKGEIAVNALWP 197
>AK058159-1|BAB71694.1| 313|Homo sapiens protein ( Homo sapiens
cDNA FLJ25430 fis, clone TST06262. ).
Length = 313
Score = 79.4 bits (187), Expect = 1e-14
Identities = 65/201 (32%), Positives = 102/201 (50%), Gaps = 10/201 (4%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
+V ++TGAS GIG A + K A + +TGR + L VA + +S + VV D
Sbjct: 8 QVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP---VVCD 64
Query: 296 MNNESDVENIIKKTVDNYHQ--LDVLVNN--AGV-----LESGTIETTSLAQYDRIMNTN 448
+ ES+V ++ ++ VD Q LDVLVNN AGV + T + +D I N
Sbjct: 65 SSQESEVRSLFEQ-VDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVG 123
Query: 449 VRGPYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA 625
+RG Y+ ++ ++ +G IV +SS L+ NV Y + K+A D+ A E+
Sbjct: 124 LRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNV-PYGVGKAACDKLAADCAHELR 182
Query: 626 LKGVRVNAVNPGVITTGLHKK 688
GV ++ PG++ T L K+
Sbjct: 183 RHGVSCVSLWPGIVQTELLKE 203
>AF418205-1|AAN32660.1| 313|Homo sapiens dehydrogenase/reductase
SDR family member 1 protein.
Length = 313
Score = 79.4 bits (187), Expect = 1e-14
Identities = 65/201 (32%), Positives = 102/201 (50%), Gaps = 10/201 (4%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
+V ++TGAS GIG A + K A + +TGR + L VA + +S + VV D
Sbjct: 8 QVCVVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP---VVCD 64
Query: 296 MNNESDVENIIKKTVDNYHQ--LDVLVNN--AGV-----LESGTIETTSLAQYDRIMNTN 448
+ ES+V ++ ++ VD Q LDVLVNN AGV + T + +D I N
Sbjct: 65 SSQESEVRSLFEQ-VDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVG 123
Query: 449 VRGPYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA 625
+RG Y+ ++ ++ +G IV +SS L+ NV Y + K+A D+ A E+
Sbjct: 124 LRGHYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNV-PYGVGKAACDKLAADCAHELR 182
Query: 626 LKGVRVNAVNPGVITTGLHKK 688
GV ++ PG++ T L K+
Sbjct: 183 RHGVSCVSLWPGIVQTELLKE 203
>AF229845-1|AAF63160.1| 311|Homo sapiens photoreceptor outer
segment all-trans retinol dehydrogenase protein.
Length = 311
Score = 79.0 bits (186), Expect = 2e-14
Identities = 64/200 (32%), Positives = 102/200 (51%), Gaps = 7/200 (3%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFA---KLNAKLVLTGR---KKENLDNVASDCESQSPSKI 271
A + V+I+G SSGIG E A + A K ++V T R KKE L+ A + Q+
Sbjct: 4 APRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQT---- 59
Query: 272 KPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNV 451
+ VA ++ SD E++ + ++DVLVNNAG+ G +E SLA + +TN
Sbjct: 60 ---LTVAQLDVCSD-ESVAQCLSCIQGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNF 115
Query: 452 RGPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
G L +P + + + G+IV +SSV GL+ Y SK A++ F +A+++
Sbjct: 116 FGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQ 175
Query: 629 KGVRVNAVNPGVITTGLHKK 688
+ ++ V PG + T K
Sbjct: 176 FNIFISLVEPGPVVTEFEGK 195
>U05659-1|AAC50066.1| 310|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 3 protein.
Length = 310
Score = 78.2 bits (184), Expect = 3e-14
Identities = 57/207 (27%), Positives = 102/207 (49%), Gaps = 6/207 (2%)
Frame = +2
Query: 83 WKLLCTEMFAN--KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQ 256
WK+L + + +ITGA GIG ++E AK +VL R E L+ +A++ E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 257 SPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRI 436
+ +K ++ AD + E+I +K ++ +LVNN G+L + + + L D I
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAG--LEIGILVNNVGMLPN-LLPSHFLNAPDEI 150
Query: 437 ---MNTNVRGPYYLTMLAIPHL-IKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ N+ +T L + H+ + KG I+N+SS L +P Y SK+ + F++
Sbjct: 151 QSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSK 210
Query: 605 CVALEVALKGVRVNAVNPGVITTGLHK 685
+ E K V + + P ++T + K
Sbjct: 211 ALQEEYKAKEVIIQVLTPYAVSTAMTK 237
>CR541894-1|CAG46692.1| 310|Homo sapiens HSD17B3 protein.
Length = 310
Score = 78.2 bits (184), Expect = 3e-14
Identities = 57/207 (27%), Positives = 102/207 (49%), Gaps = 6/207 (2%)
Frame = +2
Query: 83 WKLLCTEMFAN--KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQ 256
WK+L + + +ITGA GIG ++E AK +VL R E L+ +A++ E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 257 SPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRI 436
+ +K ++ AD + E+I +K ++ +LVNN G+L + + + L D I
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAG--LEIGILVNNVGMLPN-LLPSHFLNAPDEI 150
Query: 437 ---MNTNVRGPYYLTMLAIPHL-IKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ N+ +T L + H+ + KG I+N+SS L +P Y SK+ + F++
Sbjct: 151 QSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSK 210
Query: 605 CVALEVALKGVRVNAVNPGVITTGLHK 685
+ E K V + + P ++T + K
Sbjct: 211 ALQEEYKAKEVIIQVLTPYAVSTAMTK 237
>BC034281-1|AAH34281.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 78.2 bits (184), Expect = 3e-14
Identities = 57/207 (27%), Positives = 102/207 (49%), Gaps = 6/207 (2%)
Frame = +2
Query: 83 WKLLCTEMFAN--KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQ 256
WK+L + + +ITGA GIG ++E AK +VL R E L+ +A++ E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 257 SPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRI 436
+ +K ++ AD + E+I +K ++ +LVNN G+L + + + L D I
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAG--LEIGILVNNVGMLPN-LLPSHFLNAPDEI 150
Query: 437 ---MNTNVRGPYYLTMLAIPHL-IKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ N+ +T L + H+ + KG I+N+SS L +P Y SK+ + F++
Sbjct: 151 QSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSK 210
Query: 605 CVALEVALKGVRVNAVNPGVITTGLHK 685
+ E K V + + P ++T + K
Sbjct: 211 ALQEEYKAKEVIIQVLTPYAVSTAMTK 237
>AY341031-1|AAP88937.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 78.2 bits (184), Expect = 3e-14
Identities = 57/207 (27%), Positives = 102/207 (49%), Gaps = 6/207 (2%)
Frame = +2
Query: 83 WKLLCTEMFAN--KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQ 256
WK+L + + +ITGA GIG ++E AK +VL R E L+ +A++ E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 257 SPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRI 436
+ +K ++ AD + E+I +K ++ +LVNN G+L + + + L D I
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAG--LEIGILVNNVGMLPN-LLPSHFLNAPDEI 150
Query: 437 ---MNTNVRGPYYLTMLAIPHL-IKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ N+ +T L + H+ + KG I+N+SS L +P Y SK+ + F++
Sbjct: 151 QSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSK 210
Query: 605 CVALEVALKGVRVNAVNPGVITTGLHK 685
+ E K V + + P ++T + K
Sbjct: 211 ALQEEYKAKEVIIQVLTPYAVSTAMTK 237
>AL160269-3|CAH71615.1| 310|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 310
Score = 78.2 bits (184), Expect = 3e-14
Identities = 57/207 (27%), Positives = 102/207 (49%), Gaps = 6/207 (2%)
Frame = +2
Query: 83 WKLLCTEMFAN--KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQ 256
WK+L + + +ITGA GIG ++E AK +VL R E L+ +A++ E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 257 SPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRI 436
+ +K ++ AD + E+I +K ++ +LVNN G+L + + + L D I
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAG--LEIGILVNNVGMLPN-LLPSHFLNAPDEI 150
Query: 437 ---MNTNVRGPYYLTMLAIPHL-IKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ N+ +T L + H+ + KG I+N+SS L +P Y SK+ + F++
Sbjct: 151 QSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSK 210
Query: 605 CVALEVALKGVRVNAVNPGVITTGLHK 685
+ E K V + + P ++T + K
Sbjct: 211 ALQEEYKAKEVIIQVLTPYAVSTAMTK 237
>BC015943-1|AAH15943.1| 313|Homo sapiens DHRS1 protein protein.
Length = 313
Score = 77.8 bits (183), Expect = 4e-14
Identities = 64/198 (32%), Positives = 100/198 (50%), Gaps = 10/198 (5%)
Frame = +2
Query: 125 IITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADMNN 304
++TGAS GIG A + K A + +TGR + L VA + +S + VV D +
Sbjct: 11 VVTGASRGIGRGIALQLCKAGATVYITGRHLDTLRVVAQEAQSLGGQCVP---VVCDSSQ 67
Query: 305 ESDVENIIKKTVDNYHQ--LDVLVNN--AGV-----LESGTIETTSLAQYDRIMNTNVRG 457
ES+V ++ ++ VD Q LDVLVNN AGV + T + +D I N +RG
Sbjct: 68 ESEVRSLFEQ-VDREQQGRLDVLVNNAYAGVQTILNTRNKAFWETPASMWDDINNVGLRG 126
Query: 458 PYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKG 634
Y+ ++ ++ +G IV +SS L+ NV Y + K+A D+ A E+ G
Sbjct: 127 HYFCSVYGARLMVPAGQGLIVVISSPGSLQYMFNV-PYGVGKAACDKLAADCAHELRRHG 185
Query: 635 VRVNAVNPGVITTGLHKK 688
V ++ PG++ T L K+
Sbjct: 186 VSCVSLWPGIVQTELLKE 203
>CR457180-1|CAG33461.1| 318|Homo sapiens RDH11 protein.
Length = 318
Score = 77.4 bits (182), Expect = 5e-14
Identities = 65/207 (31%), Positives = 104/207 (50%), Gaps = 13/207 (6%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
T KVV++TGA++GIG ETA E A+ A++ L R E + VA + ++ + ++ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QV 94
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
LV D+++ + K + L VL+NNAGV+ +T ++ + N G
Sbjct: 95 LVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLG 152
Query: 458 PYYLTMLAIPHLIKT-KGNIVNVSSVT---GLRSFPNV---------LAYCISKSAIDQF 598
+ LT L + L ++ IVNVSS+ G F N+ LAYC SK A F
Sbjct: 153 HFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 599 TRCVALEVALKGVRVNAVNPGVITTGL 679
T+ +A + GV +V+PG + + L
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSEL 239
>BC037302-1|AAH37302.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 77.4 bits (182), Expect = 5e-14
Identities = 65/207 (31%), Positives = 104/207 (50%), Gaps = 13/207 (6%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
T KVV++TGA++GIG ETA E A+ A++ L R E + VA + ++ + ++ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QV 94
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
LV D+++ + K + L VL+NNAGV+ +T ++ + N G
Sbjct: 95 LVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLG 152
Query: 458 PYYLTMLAIPHLIKT-KGNIVNVSSVT---GLRSFPNV---------LAYCISKSAIDQF 598
+ LT L + L ++ IVNVSS+ G F N+ LAYC SK A F
Sbjct: 153 HFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 599 TRCVALEVALKGVRVNAVNPGVITTGL 679
T+ +A + GV +V+PG + + L
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSEL 239
>BC026274-1|AAH26274.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 77.4 bits (182), Expect = 5e-14
Identities = 65/207 (31%), Positives = 104/207 (50%), Gaps = 13/207 (6%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
T KVV++TGA++GIG ETA E A+ A++ L R E + VA + ++ + ++ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QV 94
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
LV D+++ + K + L VL+NNAGV+ +T ++ + N G
Sbjct: 95 LVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLG 152
Query: 458 PYYLTMLAIPHLIKT-KGNIVNVSSVT---GLRSFPNV---------LAYCISKSAIDQF 598
+ LT L + L ++ IVNVSS+ G F N+ LAYC SK A F
Sbjct: 153 HFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 599 TRCVALEVALKGVRVNAVNPGVITTGL 679
T+ +A + GV +V+PG + + L
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSEL 239
>BC011727-1|AAH11727.1| 318|Homo sapiens RDH11 protein protein.
Length = 318
Score = 77.4 bits (182), Expect = 5e-14
Identities = 65/207 (31%), Positives = 104/207 (50%), Gaps = 13/207 (6%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
T KVV++TGA++GIG ETA E A+ A++ L R E + VA + ++ + ++ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QV 94
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
LV D+++ + K + L VL+NNAGV+ +T ++ + N G
Sbjct: 95 LVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLG 152
Query: 458 PYYLTMLAIPHLIKT-KGNIVNVSSVT---GLRSFPNV---------LAYCISKSAIDQF 598
+ LT L + L ++ IVNVSS+ G F N+ LAYC SK A F
Sbjct: 153 HFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 599 TRCVALEVALKGVRVNAVNPGVITTGL 679
T+ +A + GV +V+PG + + L
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSEL 239
>BC000112-1|AAH00112.1| 318|Homo sapiens retinol dehydrogenase 11
(all-trans/9-cis/11-cis) protein.
Length = 318
Score = 77.4 bits (182), Expect = 5e-14
Identities = 65/207 (31%), Positives = 104/207 (50%), Gaps = 13/207 (6%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
T KVV++TGA++GIG ETA E A+ A++ L R E + VA + ++ + ++ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QV 94
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
LV D+++ + K + L VL+NNAGV+ +T ++ + N G
Sbjct: 95 LVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLG 152
Query: 458 PYYLTMLAIPHLIKT-KGNIVNVSSVT---GLRSFPNV---------LAYCISKSAIDQF 598
+ LT L + L ++ IVNVSS+ G F N+ LAYC SK A F
Sbjct: 153 HFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 599 TRCVALEVALKGVRVNAVNPGVITTGL 679
T+ +A + GV +V+PG + + L
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSEL 239
>AY358473-1|AAQ88837.1| 331|Homo sapiens RDH13 protein.
Length = 331
Score = 77.4 bits (182), Expect = 5e-14
Identities = 60/202 (29%), Positives = 95/202 (47%), Gaps = 14/202 (6%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
K VI+TGA++GIG +TA E A+ ++L R E + A D ++ + D
Sbjct: 39 KTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNH-HVNARHLD 97
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + K ++ ++D+L+NNAGV+ T+ ++ N G + LT
Sbjct: 98 LASLKSIREFAAKIIEEEERVDILINNAGVMRCP--HWTTEDGFEMQFGVNHLGHFLLTN 155
Query: 476 LAIPHL-IKTKGNIVNVSS---VTG----------LRSFPNVLAYCISKSAIDQFTRCVA 613
L + L I+N+SS V G R + AYC SK AI FT+ ++
Sbjct: 156 LLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELS 215
Query: 614 LEVALKGVRVNAVNPGVITTGL 679
+ GV VNA++PGV T L
Sbjct: 216 RRLQGSGVTVNALHPGVARTEL 237
>AF395068-1|AAK72049.1| 318|Homo sapiens HCV core-binding protein
HCBP12 protein.
Length = 318
Score = 77.4 bits (182), Expect = 5e-14
Identities = 65/207 (31%), Positives = 104/207 (50%), Gaps = 13/207 (6%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
T KVV++TGA++GIG ETA E A+ A++ L R E + VA + ++ + ++ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QV 94
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
LV D+++ + K + L VL+NNAGV+ +T ++ + N G
Sbjct: 95 LVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLG 152
Query: 458 PYYLTMLAIPHLIKT-KGNIVNVSSVT---GLRSFPNV---------LAYCISKSAIDQF 598
+ LT L + L ++ IVNVSS+ G F N+ LAYC SK A F
Sbjct: 153 HFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 599 TRCVALEVALKGVRVNAVNPGVITTGL 679
T+ +A + GV +V+PG + + L
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSEL 239
>AF167438-1|AAF89632.1| 318|Homo sapiens androgen-regulated
short-chain dehydrogenase/reductase 1 protein.
Length = 318
Score = 77.4 bits (182), Expect = 5e-14
Identities = 65/207 (31%), Positives = 104/207 (50%), Gaps = 13/207 (6%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
T KVV++TGA++GIG ETA E A+ A++ L R E + VA + ++ + ++ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QV 94
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
LV D+++ + K + L VL+NNAGV+ +T ++ + N G
Sbjct: 95 LVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLG 152
Query: 458 PYYLTMLAIPHLIKT-KGNIVNVSSVT---GLRSFPNV---------LAYCISKSAIDQF 598
+ LT L + L ++ IVNVSS+ G F N+ LAYC SK A F
Sbjct: 153 HFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 599 TRCVALEVALKGVRVNAVNPGVITTGL 679
T+ +A + GV +V+PG + + L
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSEL 239
>AF151840-1|AAD34077.1| 318|Homo sapiens CGI-82 protein protein.
Length = 318
Score = 77.4 bits (182), Expect = 5e-14
Identities = 65/207 (31%), Positives = 104/207 (50%), Gaps = 13/207 (6%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
T KVV++TGA++GIG ETA E A+ A++ L R E + VA + ++ + ++ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QV 94
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
LV D+++ + K + L VL+NNAGV+ +T ++ + N G
Sbjct: 95 LVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLG 152
Query: 458 PYYLTMLAIPHLIKT-KGNIVNVSSVT---GLRSFPNV---------LAYCISKSAIDQF 598
+ LT L + L ++ IVNVSS+ G F N+ LAYC SK A F
Sbjct: 153 HFLLTHLLLEKLKESAPSRIVNVSSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 212
Query: 599 TRCVALEVALKGVRVNAVNPGVITTGL 679
T+ +A + GV +V+PG + + L
Sbjct: 213 TQELARRLKGSGVTTYSVHPGTVQSEL 239
>BC025724-1|AAH25724.1| 316|Homo sapiens retinol dehydrogenase 12
(all-trans/9-cis/11-cis) protein.
Length = 316
Score = 77.0 bits (181), Expect = 7e-14
Identities = 63/201 (31%), Positives = 99/201 (49%), Gaps = 13/201 (6%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KVV+ITGA++GIG ETA E A A++ + R ++ AS+ + + + LV D
Sbjct: 40 KVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNS-QVLVRKLD 98
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+++ + + + QL +L+NNAGV+ +T ++ + N G + LT
Sbjct: 99 LSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTAD--GFETHLGVNHLGHFLLTY 156
Query: 476 LAIPHL-IKTKGNIVNVSSVT---------GLRS---FPNVLAYCISKSAIDQFTRCVAL 616
L + L + +VNVSSV L+S + AYC SK A FTR +A
Sbjct: 157 LLLEQLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELAK 216
Query: 617 EVALKGVRVNAVNPGVITTGL 679
+ GV AV+PGV+ + L
Sbjct: 217 RLQGTGVTTYAVHPGVVRSEL 237
>AK054835-1|BAB70811.1| 316|Homo sapiens (ARSDR1) mRNA. protein.
Length = 316
Score = 77.0 bits (181), Expect = 7e-14
Identities = 63/201 (31%), Positives = 99/201 (49%), Gaps = 13/201 (6%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KVV+ITGA++GIG ETA E A A++ + R ++ AS+ + + + LV D
Sbjct: 40 KVVVITGANTGIGKETARELASRGARVYIACRDVLKGESAASEIRVDTKNS-QVLVRKLD 98
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+++ + + + QL +L+NNAGV+ +T ++ + N G + LT
Sbjct: 99 LSDTKSIRAFAEGFLAEEKQLHILINNAGVMMCPYSKTAD--GFETHLGVNHLGHFLLTY 156
Query: 476 LAIPHL-IKTKGNIVNVSSVT---------GLRS---FPNVLAYCISKSAIDQFTRCVAL 616
L + L + +VNVSSV L+S + AYC SK A FTR +A
Sbjct: 157 LLLERLKVSAPARVVNVSSVAHHIGKIPFHDLQSEKRYSRGFAYCHSKLANVLFTRELAK 216
Query: 617 EVALKGVRVNAVNPGVITTGL 679
+ GV AV+PGV+ + L
Sbjct: 217 RLQGTGVTTYAVHPGVVRSEL 237
>AK075392-1|BAC11591.1| 331|Homo sapiens protein ( Homo sapiens
cDNA PSEC0082 fis, clone NT2RP2004966, highly similar to
Retinol dehydrogenase 13 (EC 1.1.1.-). ).
Length = 331
Score = 76.2 bits (179), Expect = 1e-13
Identities = 60/202 (29%), Positives = 95/202 (47%), Gaps = 14/202 (6%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
K VI+TGA++GIG +TA E A+ ++L R E + A D ++ + D
Sbjct: 39 KTVIVTGANTGIGKQTALELARRGGNIILACRDMEKCEAAAKDIRGETLNH-HVNARHLD 97
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + K ++ ++D+L+NNAGV+ T+ ++ N G + LT
Sbjct: 98 LASLKSIRVFAAKIIEEEERVDILINNAGVMRCP--HWTTEDGFEMQFGVNHLGHFLLTN 155
Query: 476 LAIPHL-IKTKGNIVNVSS---VTG----------LRSFPNVLAYCISKSAIDQFTRCVA 613
L + L I+N+SS V G R + AYC SK AI FT+ ++
Sbjct: 156 LLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKELS 215
Query: 614 LEVALKGVRVNAVNPGVITTGL 679
+ GV VNA++PGV T L
Sbjct: 216 RRLQGSGVTVNALHPGVARTEL 237
>BC028298-1|AAH28298.1| 318|Homo sapiens retinol dehydrogenase 5
(11-cis/9-cis) protein.
Length = 318
Score = 75.4 bits (177), Expect = 2e-13
Identities = 57/194 (29%), Positives = 96/194 (49%), Gaps = 6/194 (3%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLV---LTGRKKENLDNVASDCESQSPSKIKPL 280
+N +V ITG SG G A + + +++ LT E+L VAS S++
Sbjct: 27 SNALVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVAS-------SRLHTT 79
Query: 281 VVVADMNNESDVENIIKKTVDNYHQLDV--LVNNAGVLES-GTIETTSLAQYDRIMNTNV 451
++ D+ + V+ K + + + LVNNAGV G + + R++N N
Sbjct: 80 LL--DITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNT 137
Query: 452 RGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
GP +T+ +P L + +G ++N++SV G R N YC+SK ++ F+ + +VA
Sbjct: 138 MGPIGVTLALLPLLQQARGRVINITSVLG-RLAANGGGYCVSKFGLEAFSDSLRRDVAHF 196
Query: 632 GVRVNAVNPGVITT 673
G+RV+ V PG T
Sbjct: 197 GIRVSIVEPGFFRT 210
>U43559-1|AAC50725.1| 318|Homo sapiens 11-cis retinol dehydrogenase
protein.
Length = 318
Score = 74.5 bits (175), Expect = 4e-13
Identities = 57/194 (29%), Positives = 95/194 (48%), Gaps = 6/194 (3%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLV---LTGRKKENLDNVASDCESQSPSKIKPL 280
+N V ITG SG G A + + +++ LT E+L VAS S++
Sbjct: 27 SNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVAS-------SRLHTT 79
Query: 281 VVVADMNNESDVENIIKKTVDNYHQLDV--LVNNAGVLES-GTIETTSLAQYDRIMNTNV 451
++ D+ + V+ K + + + LVNNAGV G + + R++N N
Sbjct: 80 LL--DITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNT 137
Query: 452 RGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
GP +T+ +P L + +G ++N++SV G R N YC+SK ++ F+ + +VA
Sbjct: 138 MGPIGVTLALLPLLQQARGRVINITSVLG-RLAANGGGYCVSKFGLEAFSDSLRRDVAHF 196
Query: 632 GVRVNAVNPGVITT 673
G+RV+ V PG T
Sbjct: 197 GIRVSIVEPGFFRT 210
>AF037062-1|AAC09250.1| 318|Homo sapiens retinol dehydrogenase
protein.
Length = 318
Score = 74.5 bits (175), Expect = 4e-13
Identities = 57/194 (29%), Positives = 95/194 (48%), Gaps = 6/194 (3%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLV---LTGRKKENLDNVASDCESQSPSKIKPL 280
+N V ITG SG G A + + +++ LT E+L VAS S++
Sbjct: 27 SNAFVFITGCDSGFGRLLALQLDQRGFRVLASCLTPSGAEDLQRVAS-------SRLHTT 79
Query: 281 VVVADMNNESDVENIIKKTVDNYHQLDV--LVNNAGVLES-GTIETTSLAQYDRIMNTNV 451
++ D+ + V+ K + + + LVNNAGV G + + R++N N
Sbjct: 80 LL--DITDPQSVQQAAKWVEMHVKEAGLFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNT 137
Query: 452 RGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
GP +T+ +P L + +G ++N++SV G R N YC+SK ++ F+ + +VA
Sbjct: 138 MGPIGVTLALLPLLQQARGRVINITSVLG-RLAANGGGYCVSKFGLEAFSDSLRRDVAHF 196
Query: 632 GVRVNAVNPGVITT 673
G+RV+ V PG T
Sbjct: 197 GIRVSIVEPGFFRT 210
>X87176-1|CAA60643.1| 736|Homo sapiens 17beta-hydroxysteroid
dehydrogenase protein.
Length = 736
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/189 (26%), Positives = 92/189 (48%), Gaps = 5/189 (2%)
Frame = +2
Query: 107 FANKVVIITGASSGIGAETAYEFAKLNAKLVLTGR----KKENLDNVASDCESQSPSKIK 274
F +VV++TGA +G+G A FA+ A +V+ K ++A+D + + +
Sbjct: 7 FDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR-R 65
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVR 454
VA+ ++ + E ++K +D + ++DV+VNNAG+L + S +D I ++R
Sbjct: 66 GGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLR 125
Query: 455 GPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
G + +T A H+ K K G I+ SS +G+ Y +K + +A+E
Sbjct: 126 GSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKS 185
Query: 632 GVRVNAVNP 658
+ N + P
Sbjct: 186 NIHCNTIAP 194
>BC003098-1|AAH03098.1| 736|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 4 protein.
Length = 736
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/189 (26%), Positives = 92/189 (48%), Gaps = 5/189 (2%)
Frame = +2
Query: 107 FANKVVIITGASSGIGAETAYEFAKLNAKLVLTGR----KKENLDNVASDCESQSPSKIK 274
F +VV++TGA +G+G A FA+ A +V+ K ++A+D + + +
Sbjct: 7 FDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR-R 65
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVR 454
VA+ ++ + E ++K +D + ++DV+VNNAG+L + S +D I ++R
Sbjct: 66 GGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLR 125
Query: 455 GPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
G + +T A H+ K K G I+ SS +G+ Y +K + +A+E
Sbjct: 126 GSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKS 185
Query: 632 GVRVNAVNP 658
+ N + P
Sbjct: 186 NIHCNTIAP 194
>AF057740-1|AAD08652.1| 736|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase IV protein.
Length = 736
Score = 72.9 bits (171), Expect = 1e-12
Identities = 50/189 (26%), Positives = 92/189 (48%), Gaps = 5/189 (2%)
Frame = +2
Query: 107 FANKVVIITGASSGIGAETAYEFAKLNAKLVLTGR----KKENLDNVASDCESQSPSKIK 274
F +VV++TGA +G+G A FA+ A +V+ K ++A+D + + +
Sbjct: 7 FDGRVVLVTGAGAGLGRAYALAFAERGALVVVNDLGGDFKGVGKGSLAADKVVEEIRR-R 65
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVR 454
VA+ ++ + E ++K +D + ++DV+VNNAG+L + S +D I ++R
Sbjct: 66 GGKAVANYDSVEEGEKVVKTALDAFGRIDVVVNNAGILRDRSFARISDEDWDIIHRVHLR 125
Query: 455 GPYYLTMLAIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
G + +T A H+ K K G I+ SS +G+ Y +K + +A+E
Sbjct: 126 GSFQVTRAAWEHMKKQKYGRIIMTSSASGIYGNFGQANYSAAKLGLLGLANSLAIEGRKS 185
Query: 632 GVRVNAVNP 658
+ N + P
Sbjct: 186 NIHCNTIAP 194
>AB083038-1|BAB91014.1| 309|Homo sapiens retinal short chain
dehydrogenase reductase protein.
Length = 309
Score = 72.5 bits (170), Expect = 2e-12
Identities = 49/194 (25%), Positives = 86/194 (44%), Gaps = 4/194 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A ++V+ITGA SG+G A +FA+L + LVL KE + ++++
Sbjct: 39 AGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVR--AYT 96
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D + + V + + + +L+NNAG++ ++ + N + +
Sbjct: 97 CDCSQKEGVYRVADQVKKEIGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 470 TMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL---KGV 637
+P +I G++V +SS GL + YC SK A F V +E + KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 638 RVNAVNPGVITTGL 679
+ V P I TG+
Sbjct: 217 KTTIVCPFFIKTGM 230
>BT019371-1|AAV38178.1| 260|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 3 protein.
Length = 260
Score = 72.1 bits (169), Expect = 2e-12
Identities = 55/195 (28%), Positives = 96/195 (49%), Gaps = 6/195 (3%)
Frame = +2
Query: 83 WKLLCTEMFAN--KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQ 256
WK+L + + +ITGA GIG ++E AK +VL R E L+ +A++ E
Sbjct: 36 WKVLPKSFLRSMGQWAVITGAGDGIGKAYSFELAKRGLNVVLISRTLEKLEAIATEIERT 95
Query: 257 SPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRI 436
+ +K ++ AD + E+I +K ++ +LVNN G+L + + + L D I
Sbjct: 96 TGRSVK--IIQADFTKDDIYEHIKEKLAG--LEIGILVNNVGMLPN-LLPSHFLNAPDEI 150
Query: 437 ---MNTNVRGPYYLTMLAIPHL-IKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTR 604
++ N+ +T L + H+ + KG I+N+SS L +P Y SK+ + F++
Sbjct: 151 QSLIHCNITSVVKMTQLILKHMESRQKGLILNISSGIALFPWPLYSMYSASKAFVCAFSK 210
Query: 605 CVALEVALKGVRVNA 649
+ E K V + A
Sbjct: 211 ALQEEYKAKEVIIQA 225
>U89717-1|AAB93668.1| 318|Homo sapiens 9-cis-retinol specific
dehydrogenase protein.
Length = 318
Score = 71.7 bits (168), Expect = 3e-12
Identities = 56/192 (29%), Positives = 92/192 (47%), Gaps = 4/192 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLV---LTGRKKENLDNVASDCESQSPSKIKPL 280
+N V ITG SG G A + + + +++ LT E+L VAS + + L
Sbjct: 27 SNAFVFITGCDSGFGRLLALQLDQKSFRVLASCLTPSGAEDLQGVASSGFNTT------L 80
Query: 281 VVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLES-GTIETTSLAQYDRIMNTNVRG 457
+ + D + ++ V L LVNNAGV G + + R++N N G
Sbjct: 81 LDITDPQSFQQAAKWVEMHVKEAG-LFGLVNNAGVAGIIGPTPWLTRDDFQRVLNVNTMG 139
Query: 458 PYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGV 637
P +T+ +P L + +G ++N++SV G R N YC+SK ++ F+ + +VA G+
Sbjct: 140 PIGVTLALLPLLQQARGRVINITSVLG-RLAANGGGYCVSKFGLEAFSDSLRRDVAHFGI 198
Query: 638 RVNAVNPGVITT 673
R + V PG T
Sbjct: 199 RESIVEPGFFRT 210
>BC064525-1|AAH64525.1| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 4/194 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A ++V+ITGA SG+G A +FA+L + LVL KE + +++
Sbjct: 39 AGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVH--AYT 96
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D + + V + + + +L+NNAG++ ++ + N + +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 470 TMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL---KGV 637
+P +I G++V +SS GL + YC SK A F V +E + KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 638 RVNAVNPGVITTGL 679
+ V P I TG+
Sbjct: 217 KTTIVCPFFIKTGM 230
>BC037219-1|AAH37219.2| 309|Homo sapiens epidermal retinal
dehydrogenase 2 protein.
Length = 309
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/194 (25%), Positives = 85/194 (43%), Gaps = 4/194 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A ++V+ITGA SG+G A +FA+L + LVL KE + +++
Sbjct: 39 AGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVH--AYT 96
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D + + V + + + +L+NNAG++ ++ + N + +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 470 TMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL---KGV 637
+P +I G++V +SS GL + YC SK A F V +E + KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 638 RVNAVNPGVITTGL 679
+ V P I TG+
Sbjct: 217 KTTIVCPFFIKTGM 230
>BC002730-1|AAH02730.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 3/182 (1%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNA-KLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V+ITG GIG + A EFA+ A K+VL GR ++ L + + + D+
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMG---TECHYFICDV 97
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTML 478
N +V K + + +LVNNA V+ ++ + + + N G ++ T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 479 AIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNAV 652
+P +++ + G+IV ++SV L + P + YC SK++ F + L + GV V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 653 NP 658
P
Sbjct: 218 LP 219
>AL645761-1|CAI14999.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 3/182 (1%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNA-KLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V+ITG GIG + A EFA+ A K+VL GR ++ L + + + D+
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMG---TECHYFICDV 97
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTML 478
N +V K + + +LVNNA V+ ++ + + + N G ++ T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 479 AIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNAV 652
+P +++ + G+IV ++SV L + P + YC SK++ F + L + GV V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 653 NP 658
P
Sbjct: 218 LP 219
>AL513016-1|CAH74172.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 protein.
Length = 302
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 3/182 (1%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNA-KLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V+ITG GIG + A EFA+ A K+VL GR ++ L + + + D+
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMG---TECHYFICDV 97
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTML 478
N +V K + + +LVNNA V+ ++ + + + N G ++ T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 479 AIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNAV 652
+P +++ + G+IV ++SV L + P + YC SK++ F + L + GV V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 653 NP 658
P
Sbjct: 218 LP 219
>AK222593-1|BAD96313.1| 302|Homo sapiens dehydrogenase/reductase
(SDR family) member 3 variant protein.
Length = 302
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 3/182 (1%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNA-KLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V+ITG GIG + A EFA+ A K+VL GR ++ L + + + D+
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMG---TECHYFICDV 97
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTML 478
N +V K + + +LVNNA V+ ++ + + + N G ++ T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 479 AIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNAV 652
+P +++ + G+IV ++SV L + P + YC SK++ F + L + GV V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 653 NP 658
P
Sbjct: 218 LP 219
>AF179237-1|AAD55402.1| 302|Homo sapiens short-chain
dehydrogenase/reductase 1 protein.
Length = 302
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 3/182 (1%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNA-KLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V+ITG GIG + A EFA+ A K+VL GR ++ L + + + D+
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMG---TECHYFICDV 97
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTML 478
N +V K + + +LVNNA V+ ++ + + + N G ++ T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 479 AIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNAV 652
+P +++ + G+IV ++SV L + P + YC SK++ F + L + GV V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 653 NP 658
P
Sbjct: 218 LP 219
>AF061741-1|AAC63263.1| 302|Homo sapiens retinal short-chain
dehydrogenase/reductase retSDR1 protein.
Length = 302
Score = 71.3 bits (167), Expect = 4e-12
Identities = 49/182 (26%), Positives = 85/182 (46%), Gaps = 3/182 (1%)
Frame = +2
Query: 122 VIITGASSGIGAETAYEFAKLNA-KLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V+ITG GIG + A EFA+ A K+VL GR ++ L + + + D+
Sbjct: 41 VLITGGGRGIGRQLAREFAERGARKIVLWGRTEKCLKETTEEIRQMG---TECHYFICDV 97
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTML 478
N +V K + + +LVNNA V+ ++ + + + N G ++ T
Sbjct: 98 GNREEVYQTAKAVREKVGDITILVNNAAVVHGKSLMDSDDDALLKSQHINTLGQFWTTKA 157
Query: 479 AIPHLIKTK-GNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA-LKGVRVNAV 652
+P +++ + G+IV ++SV L + P + YC SK++ F + L + GV V
Sbjct: 158 FLPRMLELQNGHIVCLNSVLALSAIPGAIDYCTSKASAFAFMESLTLGLLDCPGVSATTV 217
Query: 653 NP 658
P
Sbjct: 218 LP 219
>BC020710-1|AAH20710.1| 317|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 6 homolog (mouse) protein.
Length = 317
Score = 69.3 bits (162), Expect = 1e-11
Identities = 52/191 (27%), Positives = 94/191 (49%), Gaps = 2/191 (1%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVV-V 289
+K V ITG SG G A + +++ ++ A Q+ +++ + + V
Sbjct: 29 DKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKG----AEQLRGQTSDRLETVTLDV 84
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPYY 466
M + + +K+ V + L LVNNAG+L T+ E + ++ N+ G
Sbjct: 85 TKMESIAAATQWVKEHVGD-RGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQ 143
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T+ +P + + +G IVNVSS+ G +F V YC+SK ++ F+ + E+ GV+++
Sbjct: 144 VTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHFGVKIS 202
Query: 647 AVNPGVITTGL 679
V PG TG+
Sbjct: 203 IVEPGYFRTGM 213
>AF223225-1|AAF81017.1| 317|Homo sapiens 3-hydroxysteroid epimerase
protein.
Length = 317
Score = 69.3 bits (162), Expect = 1e-11
Identities = 52/191 (27%), Positives = 94/191 (49%), Gaps = 2/191 (1%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVV-V 289
+K V ITG SG G A + +++ ++ A Q+ +++ + + V
Sbjct: 29 DKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKG----AEQLRGQTSDRLETVTLDV 84
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPYY 466
M + + +K+ V + L LVNNAG+L T+ E + ++ N+ G
Sbjct: 85 TKMESIAAATQWVKEHVGD-RGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQ 143
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T+ +P + + +G IVNVSS+ G +F V YC+SK ++ F+ + E+ GV+++
Sbjct: 144 VTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHFGVKIS 202
Query: 647 AVNPGVITTGL 679
V PG TG+
Sbjct: 203 IVEPGYFRTGM 213
>AF016509-1|AAB67236.1| 317|Homo sapiens oxidoreductase protein.
Length = 317
Score = 69.3 bits (162), Expect = 1e-11
Identities = 52/191 (27%), Positives = 94/191 (49%), Gaps = 2/191 (1%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVV-V 289
+K V ITG SG G A + +++ ++ A Q+ +++ + + V
Sbjct: 29 DKYVFITGCDSGFGNLLARQLDARGLRVLAACLTEKG----AEQLRGQTSDRLETVTLDV 84
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPYY 466
M + + +K+ V + L LVNNAG+L T+ E + ++ N+ G
Sbjct: 85 TKMESIAAATQWVKEHVGD-RGLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQ 143
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T+ +P + + +G IVNVSS+ G +F V YC+SK ++ F+ + E+ GV+++
Sbjct: 144 VTLSMLPLVRRARGRIVNVSSILGRVAF-FVGGYCVSKYGVEAFSDILRREIQHFGVKIS 202
Query: 647 AVNPGVITTGL 679
V PG TG+
Sbjct: 203 IVEPGYFRTGM 213
>X82460-1|CAA57843.1| 178|Homo sapiens 15-hydroxy prostaglandin
dehydrogenase protein.
Length = 178
Score = 67.7 bits (158), Expect = 4e-11
Identities = 49/170 (28%), Positives = 79/170 (46%), Gaps = 4/170 (2%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV ++TGA+ GIG A AK+ L E + + Q + K L + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ-KTLFIQCD 64
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ ++ + + +K VD++ +LD+LVNNAGV + +++ + N+ T
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGV--------NNKKNWEKTLQINLVSVISGTY 116
Query: 476 LAIPHLIKTKGN----IVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVA 613
L + ++ K G I+N+SS+ GL YC SK I FTR A
Sbjct: 117 LGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAA 166
>BC010740-1|AAH10740.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 67.3 bits (157), Expect = 6e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 89 LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSK 268
L C ++ +KV ITG SGIG A F + V+ R + A + +
Sbjct: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79
Query: 269 IKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTN 448
PL + D+ V + + + + ++D+L+N A S + +M+ +
Sbjct: 80 CLPLSM--DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137
Query: 449 VRGPYYLTMLAIPHLIKTKGN-IVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA 625
G + ++ + + G IVN+++ G R + +K+A+D TR +A+E
Sbjct: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197
Query: 626 LKGVRVNAVNPGVI--TTGLHKKG 691
+ +RVN++ PG I T GL + G
Sbjct: 198 PQNIRVNSLAPGPISGTEGLRRLG 221
>AL023881-5|CAB92744.1| 292|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 292
Score = 67.3 bits (157), Expect = 6e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 89 LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSK 268
L C ++ +KV ITG SGIG A F + V+ R + A + +
Sbjct: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79
Query: 269 IKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTN 448
PL + D+ V + + + + ++D+L+N A S + +M+ +
Sbjct: 80 CLPLSM--DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137
Query: 449 VRGPYYLTMLAIPHLIKTKGN-IVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA 625
G + ++ + + G IVN+++ G R + +K+A+D TR +A+E
Sbjct: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197
Query: 626 LKGVRVNAVNPGVI--TTGLHKKG 691
+ +RVN++ PG I T GL + G
Sbjct: 198 PQNIRVNSLAPGPISGTEGLRRLG 221
>AJ293009-1|CAC05664.1| 292|Homo sapiens peroxisomal
2,4-dienoyl-CoA reductase protein.
Length = 292
Score = 67.3 bits (157), Expect = 6e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 89 LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSK 268
L C ++ +KV ITG SGIG A F + V+ R + A + +
Sbjct: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79
Query: 269 IKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTN 448
PL + D+ V + + + + ++D+L+N A S + +M+ +
Sbjct: 80 CLPLSM--DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137
Query: 449 VRGPYYLTMLAIPHLIKTKGN-IVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA 625
G + ++ + + G IVN+++ G R + +K+A+D TR +A+E
Sbjct: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197
Query: 626 LKGVRVNAVNPGVI--TTGLHKKG 691
+ +RVN++ PG I T GL + G
Sbjct: 198 PQNIRVNSLAPGPISGTEGLRRLG 221
>AE006463-11|AAK61231.1| 292|Homo sapiens 2-4-dienoyl-Coenzyme A
reductase 2 peroxisomal like protein.
Length = 292
Score = 67.3 bits (157), Expect = 6e-11
Identities = 50/204 (24%), Positives = 91/204 (44%), Gaps = 3/204 (1%)
Frame = +2
Query: 89 LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSK 268
L C ++ +KV ITG SGIG A F + V+ R + A + +
Sbjct: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMRHGCHTVIASRSLPRVLTAARKLAGATGRR 79
Query: 269 IKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTN 448
PL + D+ V + + + + ++D+L+N A S + +M+ +
Sbjct: 80 CLPLSM--DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 137
Query: 449 VRGPYYLTMLAIPHLIKTKGN-IVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA 625
G + ++ + + G IVN+++ G R + +K+A+D TR +A+E
Sbjct: 138 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 197
Query: 626 LKGVRVNAVNPGVI--TTGLHKKG 691
+ +RVN++ PG I T GL + G
Sbjct: 198 PQNIRVNSLAPGPISGTEGLRRLG 221
>L40802-1|AAC41917.1| 387|Homo sapiens 17-hydroxysteroid
dehydrogenase protein.
Length = 387
Score = 66.5 bits (155), Expect = 1e-10
Identities = 53/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
K V++TG G+G +L V G EN + SP + V+ D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFT-VFAGVLNENGPGAEELRRTCSP---RLSVLQMD 138
Query: 296 MNNESDVENIIKKTVDNYHQ--LDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPYY 466
+ +++ K L ++NNAGVL T E + Y + M N G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVE 198
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T +P L K+KG +VNVSS+ G + +Y SK+A+ F+ + LE++ G++V
Sbjct: 199 VTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVA 258
Query: 647 AVNPGVITTGL 679
++ PG T +
Sbjct: 259 SIQPGGFLTNI 269
>L11708-1|AAA03562.1| 387|Homo sapiens 17 beta hydroxysteroid
dehydrogenase type 2 protein.
Length = 387
Score = 66.5 bits (155), Expect = 1e-10
Identities = 53/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
K V++TG G+G +L V G EN + SP + V+ D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFT-VFAGVLNENGPGAEELRRTCSP---RLSVLQMD 138
Query: 296 MNNESDVENIIKKTVDNYHQ--LDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPYY 466
+ +++ K L ++NNAGVL T E + Y + M N G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVE 198
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T +P L K+KG +VNVSS+ G + +Y SK+A+ F+ + LE++ G++V
Sbjct: 199 VTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVA 258
Query: 647 AVNPGVITTGL 679
++ PG T +
Sbjct: 259 SIQPGGFLTNI 269
>BC059170-1|AAH59170.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 66.5 bits (155), Expect = 1e-10
Identities = 53/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
K V++TG G+G +L V G EN + SP + V+ D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFT-VFAGVLNENGPGAEELRRTCSP---RLSVLQMD 138
Query: 296 MNNESDVENIIKKTVDNYHQ--LDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPYY 466
+ +++ K L ++NNAGVL T E + Y + M N G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVE 198
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T +P L K+KG +VNVSS+ G + +Y SK+A+ F+ + LE++ G++V
Sbjct: 199 VTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVA 258
Query: 647 AVNPGVITTGL 679
++ PG T +
Sbjct: 259 SIQPGGFLTNI 269
>BC009581-1|AAH09581.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 66.5 bits (155), Expect = 1e-10
Identities = 53/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
K V++TG G+G +L V G EN + SP + V+ D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFT-VFAGVLNENGPGAEELRRTCSP---RLSVLQMD 138
Query: 296 MNNESDVENIIKKTVDNYHQ--LDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPYY 466
+ +++ K L ++NNAGVL T E + Y + M N G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVE 198
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T +P L K+KG +VNVSS+ G + +Y SK+A+ F+ + LE++ G++V
Sbjct: 199 VTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVA 258
Query: 647 AVNPGVITTGL 679
++ PG T +
Sbjct: 259 SIQPGGFLTNI 269
>AY325910-1|AAP78485.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 protein.
Length = 387
Score = 66.5 bits (155), Expect = 1e-10
Identities = 53/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
K V++TG G+G +L V G EN + SP + V+ D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFT-VFAGVLNENGPGAEELRRTCSP---RLSVLQMD 138
Query: 296 MNNESDVENIIKKTVDNYHQ--LDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPYY 466
+ +++ K L ++NNAGVL T E + Y + M N G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVE 198
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T +P L K+KG +VNVSS+ G + +Y SK+A+ F+ + LE++ G++V
Sbjct: 199 VTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVA 258
Query: 647 AVNPGVITTGL 679
++ PG T +
Sbjct: 259 SIQPGGFLTNI 269
>AK223001-1|BAD96721.1| 387|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 2 variant protein.
Length = 387
Score = 66.5 bits (155), Expect = 1e-10
Identities = 53/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
K V++TG G+G +L V G EN + SP + V+ D
Sbjct: 83 KAVLVTGGDCGLGHALCKYLDELGFT-VFAGVLNENGPGAEELRRTCSP---RLSVLQMD 138
Query: 296 MNNESDVENIIKKTVDNYHQ--LDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPYY 466
+ +++ K L ++NNAGVL T E + Y + M N G
Sbjct: 139 ITKPVQIKDAYSKVAAMLQDRGLWAVINNAGVLGFPTDGELLLMTDYKQCMAVNFFGTVE 198
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T +P L K+KG +VNVSS+ G + +Y SK+A+ F+ + LE++ G++V
Sbjct: 199 VTKTFLPLLRKSKGRLVNVSSMGGGAPMERLASYGSSKAAVTMFSSVMRLELSKWGIKVA 258
Query: 647 AVNPGVITTGL 679
++ PG T +
Sbjct: 259 SIQPGGFLTNI 269
>AK057667-1|BAB71545.1| 231|Homo sapiens protein ( Homo sapiens
cDNA FLJ33105 fis, clone TRACH2000926, weakly similar to
PROBABLE OXIDOREDUCTASE EPHD (EC 1.-.-.-). ).
Length = 231
Score = 66.5 bits (155), Expect = 1e-10
Identities = 46/187 (24%), Positives = 81/187 (43%), Gaps = 4/187 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A ++V+ITGA SG+G A +FA+L + LVL KE + +++
Sbjct: 39 AGEIVLITGAGSGLGRLLALQFARLGSVLVLWDINKEGNEETCKMAREAGATRVH--AYT 96
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D + + V + + + +L+NNAG++ ++ + N + +
Sbjct: 97 CDCSQKEGVYRVADQVKKEVGDVSILINNAGIVTGKKFLDCPDELMEKSFDVNFKAHLWT 156
Query: 470 TMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL---KGV 637
+P +I G++V +SS GL + YC SK A F V +E + KG+
Sbjct: 157 YKAFLPAMIANDHGHLVCISSSAGLSGVNGLADYCASKFAAFGFAESVFVETFVQKQKGI 216
Query: 638 RVNAVNP 658
+ V P
Sbjct: 217 KTTIVCP 223
>U78302-1|AAB88724.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 62 SRNFTKLWK-LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVA 238
S+ F+ L K +L F KV ITG +G+G + L A+ V+ RK + L A
Sbjct: 41 SKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATA 100
Query: 239 SDCESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSL 418
SQ+ +K+ + D+ + V+N + + + ++++NNA E S
Sbjct: 101 EQISSQTGNKVH--AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSP 158
Query: 419 AQYDRIMNTNVRGPYYLTMLAIPHLIKT-KG-NIVNVSSVTGLRSFPNVLAYCISKSAID 592
+ I + + G ++T+ LIK KG ++++++ V+ +K+ ++
Sbjct: 159 NAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVE 218
Query: 593 QFTRCVALEVALKGVRVNAVNPGVITT 673
++ +A E G+R N + PG I T
Sbjct: 219 AMSKSLAAEWGKYGMRFNVIQPGPIKT 245
>U49352-1|AAB09423.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 62 SRNFTKLWK-LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVA 238
S+ F+ L K +L F KV ITG +G+G + L A+ V+ RK + L A
Sbjct: 41 SKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATA 100
Query: 239 SDCESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSL 418
SQ+ +K+ + D+ + V+N + + + ++++NNA E S
Sbjct: 101 EQISSQTGNKVH--AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSP 158
Query: 419 AQYDRIMNTNVRGPYYLTMLAIPHLIKT-KG-NIVNVSSVTGLRSFPNVLAYCISKSAID 592
+ I + + G ++T+ LIK KG ++++++ V+ +K+ ++
Sbjct: 159 NAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVE 218
Query: 593 QFTRCVALEVALKGVRVNAVNPGVITT 673
++ +A E G+R N + PG I T
Sbjct: 219 AMSKSLAAEWGKYGMRFNVIQPGPIKT 245
>L26050-1|AAA67551.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 335
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 62 SRNFTKLWK-LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVA 238
S+ F+ L K +L F KV ITG +G+G + L A+ V+ RK + L A
Sbjct: 41 SKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATA 100
Query: 239 SDCESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSL 418
SQ+ +K+ + D+ + V+N + + + ++++NNA E S
Sbjct: 101 EQISSQTGNKVH--AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSP 158
Query: 419 AQYDRIMNTNVRGPYYLTMLAIPHLIKT-KG-NIVNVSSVTGLRSFPNVLAYCISKSAID 592
+ I + + G ++T+ LIK KG ++++++ V+ +K+ ++
Sbjct: 159 NAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVE 218
Query: 593 QFTRCVALEVALKGVRVNAVNPGVITT 673
++ +A E G+R N + PG I T
Sbjct: 219 AMSKSLAAEWGKYGMRFNVIQPGPIKT 245
>BC105082-1|AAI05083.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 62 SRNFTKLWK-LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVA 238
S+ F+ L K +L F KV ITG +G+G + L A+ V+ RK + L A
Sbjct: 41 SKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATA 100
Query: 239 SDCESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSL 418
SQ+ +K+ + D+ + V+N + + + ++++NNA E S
Sbjct: 101 EQISSQTGNKVH--AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSP 158
Query: 419 AQYDRIMNTNVRGPYYLTMLAIPHLIKT-KG-NIVNVSSVTGLRSFPNVLAYCISKSAID 592
+ I + + G ++T+ LIK KG ++++++ V+ +K+ ++
Sbjct: 159 NAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVE 218
Query: 593 QFTRCVALEVALKGVRVNAVNPGVITT 673
++ +A E G+R N + PG I T
Sbjct: 219 AMSKSLAAEWGKYGMRFNVIQPGPIKT 245
>BC105080-1|AAI05081.1| 335|Homo sapiens 2,4-dienoyl CoA reductase
1, mitochondrial protein.
Length = 335
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 62 SRNFTKLWK-LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVA 238
S+ F+ L K +L F KV ITG +G+G + L A+ V+ RK + L A
Sbjct: 41 SKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATA 100
Query: 239 SDCESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSL 418
SQ+ +K+ + D+ + V+N + + + ++++NNA E S
Sbjct: 101 EQISSQTGNKVH--AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSP 158
Query: 419 AQYDRIMNTNVRGPYYLTMLAIPHLIKT-KG-NIVNVSSVTGLRSFPNVLAYCISKSAID 592
+ I + + G ++T+ LIK KG ++++++ V+ +K+ ++
Sbjct: 159 NAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVE 218
Query: 593 QFTRCVALEVALKGVRVNAVNPGVITT 673
++ +A E G+R N + PG I T
Sbjct: 219 AMSKSLAAEWGKYGMRFNVIQPGPIKT 245
>AF057034-1|AAC39922.1| 317|Homo sapiens sterol/retinol
dehydrogenase protein.
Length = 317
Score = 64.9 bits (151), Expect = 3e-10
Identities = 52/194 (26%), Positives = 92/194 (47%), Gaps = 2/194 (1%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVV-V 289
+K V ITG SG G A + +++ ++ A Q+ +++ + + V
Sbjct: 29 DKYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKG----AEQLRGQTSDRLETVTLDV 84
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVRGPYY 466
+ + +K+ V + L LVNNAG+ L + E + + I++ N+ G
Sbjct: 85 TKTESVAAAAQWVKECVRD-KGLWGLVNNAGISLPTAPNELLTKQDFVTILDVNLLGVID 143
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T+ +P + K +G +VNVSSV G S YCISK ++ F+ + E++ GV+V
Sbjct: 144 VTLSLLPLVRKARGRVVNVSSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELSYFGVKVA 202
Query: 647 AVNPGVITTGLHKK 688
+ PG T + K
Sbjct: 203 MIEPGYFKTAVTSK 216
>AC004612-1|AAC14671.1| 335|Homo sapiens 2,4-dienoyl-CoA reductase
precursor protein.
Length = 335
Score = 64.9 bits (151), Expect = 3e-10
Identities = 50/207 (24%), Positives = 95/207 (45%), Gaps = 3/207 (1%)
Frame = +2
Query: 62 SRNFTKLWK-LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVA 238
S+ F+ L K +L F KV ITG +G+G + L A+ V+ RK + L A
Sbjct: 41 SKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATA 100
Query: 239 SDCESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSL 418
SQ+ +K+ + D+ + V+N + + + ++++NNA E S
Sbjct: 101 EQISSQTGNKVH--AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSP 158
Query: 419 AQYDRIMNTNVRGPYYLTMLAIPHLIKT-KG-NIVNVSSVTGLRSFPNVLAYCISKSAID 592
+ I + + G ++T+ LIK KG ++++++ V+ +K+ ++
Sbjct: 159 NAWKTITDIVLNGTAFVTLEIGKQLIKAQKGAAFLSITTIYAETGSGFVVPSASAKAGVE 218
Query: 593 QFTRCVALEVALKGVRVNAVNPGVITT 673
++ +A E G+R N + PG I T
Sbjct: 219 AMSKSLAAEWGKYGMRFNVIQPGPIKT 245
>Z97054-8|CAI42653.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V +ITG +SG+G TA A VL +L N + +++ + AD+
Sbjct: 12 VAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGN-NCVFAPADV 65
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNVRGP 460
+E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+ G
Sbjct: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125
Query: 461 YYLTMLAIPHLIKT-------KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ + L + + +G I+N +SV AY SK I T +A +
Sbjct: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185
Query: 620 VALKGVRVNAVNPGVITTGL 679
+A G+RV + PG+ T L
Sbjct: 186 LAPIGIRVMTIAPGLFGTPL 205
>U96132-1|AAC51812.1| 261|Homo sapiens amyloid beta-peptide binding
protein protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V +ITG +SG+G TA A VL +L N + +++ + AD+
Sbjct: 12 VAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGN-NCVFAPADV 65
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNVRGP 460
+E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+ G
Sbjct: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125
Query: 461 YYLTMLAIPHLIKT-------KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ + L + + +G I+N +SV AY SK I T +A +
Sbjct: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185
Query: 620 VALKGVRVNAVNPGVITTGL 679
+A G+RV + PG+ T L
Sbjct: 186 LAPIGIRVMTIAPGLFGTPL 205
>U73514-1|AAB68958.1| 261|Homo sapiens short-chain alcohol
dehydrogenase protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V +ITG +SG+G TA A VL +L N + +++ + AD+
Sbjct: 12 VAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGN-NCVFAPADV 65
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNVRGP 460
+E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+ G
Sbjct: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125
Query: 461 YYLTMLAIPHLIKT-------KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ + L + + +G I+N +SV AY SK I T +A +
Sbjct: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185
Query: 620 VALKGVRVNAVNPGVITTGL 679
+A G+RV + PG+ T L
Sbjct: 186 LAPIGIRVMTIAPGLFGTPL 205
>CR456723-1|CAG33004.1| 261|Homo sapiens HADH2 protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V +ITG +SG+G TA A VL +L N + +++ + AD+
Sbjct: 12 VAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGN-NCVFAPADV 65
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNVRGP 460
+E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+ G
Sbjct: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125
Query: 461 YYLTMLAIPHLIKT-------KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ + L + + +G I+N +SV AY SK I T +A +
Sbjct: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185
Query: 620 VALKGVRVNAVNPGVITTGL 679
+A G+RV + PG+ T L
Sbjct: 186 LAPIGIRVMTIAPGLFGTPL 205
>BT007239-1|AAP35903.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 45/197 (22%), Positives = 90/197 (45%), Gaps = 7/197 (3%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLT----GRKKENLDNVASDCESQSPSKIKPLVV 286
+ ++TGA SGIG + A A + +E + + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 287 VADMNNESDVENIIKKTVDNYHQL-DVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
AD++ ++++ + + V+V+ AG+ + + S +D+++ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 464 YLTMLAIPHLIKT--KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGV 637
+T A L+ +G+I+N+SS+ G Y SK+ + T+ A E+ G+
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 638 RVNAVNPGVITTGLHKK 688
R N+V PG I T + +K
Sbjct: 193 RCNSVLPGFIATPMTQK 209
>BC008185-1|AAH08185.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 45/197 (22%), Positives = 90/197 (45%), Gaps = 7/197 (3%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLT----GRKKENLDNVASDCESQSPSKIKPLVV 286
+ ++TGA SGIG + A A + +E + + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 287 VADMNNESDVENIIKKTVDNYHQL-DVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
AD++ ++++ + + V+V+ AG+ + + S +D+++ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 464 YLTMLAIPHLIKT--KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGV 637
+T A L+ +G+I+N+SS+ G Y SK+ + T+ A E+ G+
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 638 RVNAVNPGVITTGLHKK 688
R N+V PG I T + +K
Sbjct: 193 RCNSVLPGFIATPMTQK 209
>BC000372-1|AAH00372.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V +ITG +SG+G TA A VL +L N + +++ + AD+
Sbjct: 12 VAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGN-NCVFAPADV 65
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNVRGP 460
+E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+ G
Sbjct: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125
Query: 461 YYLTMLAIPHLIKT-------KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ + L + + +G I+N +SV AY SK I T +A +
Sbjct: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185
Query: 620 VALKGVRVNAVNPGVITTGL 679
+A G+RV + PG+ T L
Sbjct: 186 LAPIGIRVMTIAPGLFGTPL 205
>AL844527-12|CAI41840.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 45/197 (22%), Positives = 90/197 (45%), Gaps = 7/197 (3%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLT----GRKKENLDNVASDCESQSPSKIKPLVV 286
+ ++TGA SGIG + A A + +E + + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 287 VADMNNESDVENIIKKTVDNYHQL-DVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
AD++ ++++ + + V+V+ AG+ + + S +D+++ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 464 YLTMLAIPHLIKT--KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGV 637
+T A L+ +G+I+N+SS+ G Y SK+ + T+ A E+ G+
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 638 RVNAVNPGVITTGLHKK 688
R N+V PG I T + +K
Sbjct: 193 RCNSVLPGFIATPMTQK 209
>AL713971-6|CAI17657.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 45/197 (22%), Positives = 90/197 (45%), Gaps = 7/197 (3%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLT----GRKKENLDNVASDCESQSPSKIKPLVV 286
+ ++TGA SGIG + A A + +E + + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 287 VADMNNESDVENIIKKTVDNYHQL-DVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
AD++ ++++ + + V+V+ AG+ + + S +D+++ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 464 YLTMLAIPHLIKT--KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGV 637
+T A L+ +G+I+N+SS+ G Y SK+ + T+ A E+ G+
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 638 RVNAVNPGVITTGLHKK 688
R N+V PG I T + +K
Sbjct: 193 RCNSVLPGFIATPMTQK 209
>AL662824-24|CAI17616.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 45/197 (22%), Positives = 90/197 (45%), Gaps = 7/197 (3%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLT----GRKKENLDNVASDCESQSPSKIKPLVV 286
+ ++TGA SGIG + A A + +E + + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 287 VADMNNESDVENIIKKTVDNYHQL-DVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
AD++ ++++ + + V+V+ AG+ + + S +D+++ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 464 YLTMLAIPHLIKT--KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGV 637
+T A L+ +G+I+N+SS+ G Y SK+ + T+ A E+ G+
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 638 RVNAVNPGVITTGLHKK 688
R N+V PG I T + +K
Sbjct: 193 RCNSVLPGFIATPMTQK 209
>AL645940-10|CAI18068.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 45/197 (22%), Positives = 90/197 (45%), Gaps = 7/197 (3%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLT----GRKKENLDNVASDCESQSPSKIKPLVV 286
+ ++TGA SGIG + A A + +E + + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 287 VADMNNESDVENIIKKTVDNYHQL-DVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
AD++ ++++ + + V+V+ AG+ + + S +D+++ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 464 YLTMLAIPHLIKT--KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGV 637
+T A L+ +G+I+N+SS+ G Y SK+ + T+ A E+ G+
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 638 RVNAVNPGVITTGLHKK 688
R N+V PG I T + +K
Sbjct: 193 RCNSVLPGFIATPMTQK 209
>AL031228-10|CAC38444.1| 261|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 8 protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 45/197 (22%), Positives = 90/197 (45%), Gaps = 7/197 (3%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLT----GRKKENLDNVASDCESQSPSKIKPLVV 286
+ ++TGA SGIG + A A + +E + + + P +
Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 72
Query: 287 VADMNNESDVENIIKKTVDNYHQL-DVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
AD++ ++++ + + V+V+ AG+ + + S +D+++ N++G +
Sbjct: 73 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSEDDWDKVIAVNLKGTF 132
Query: 464 YLTMLAIPHLIKT--KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGV 637
+T A L+ +G+I+N+SS+ G Y SK+ + T+ A E+ G+
Sbjct: 133 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 192
Query: 638 RVNAVNPGVITTGLHKK 688
R N+V PG I T + +K
Sbjct: 193 RCNSVLPGFIATPMTQK 209
>AF069134-1|AAC39900.1| 261|Homo sapiens putative short-chain type
dehydrogenase/reductase protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V +ITG +SG+G TA A VL +L N + +++ + AD+
Sbjct: 12 VAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGN-NCVFAPADV 65
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNVRGP 460
+E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+ G
Sbjct: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125
Query: 461 YYLTMLAIPHLIKT-------KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ + L + + +G I+N +SV AY SK I T +A +
Sbjct: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185
Query: 620 VALKGVRVNAVNPGVITTGL 679
+A G+RV + PG+ T L
Sbjct: 186 LAPIGIRVMTIAPGLFGTPL 205
>AF037438-1|AAC16419.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V +ITG +SG+G TA A VL +L N + +++ + AD+
Sbjct: 12 VAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGN-NCVFAPADV 65
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNVRGP 460
+E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+ G
Sbjct: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125
Query: 461 YYLTMLAIPHLIKT-------KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ + L + + +G I+N +SV AY SK I T +A +
Sbjct: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185
Query: 620 VALKGVRVNAVNPGVITTGL 679
+A G+RV + PG+ T L
Sbjct: 186 LAPIGIRVMTIAPGLFGTPL 205
>AF035555-1|AAC15902.1| 261|Homo sapiens 17beta-hydroxysteroid
dehydrogenase type 10/short chain L-3-hydroxyacyl-CoA
deh protein.
Length = 261
Score = 64.1 bits (149), Expect = 5e-10
Identities = 53/200 (26%), Positives = 91/200 (45%), Gaps = 13/200 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V +ITG +SG+G TA A VL +L N + +++ + AD+
Sbjct: 12 VAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGN-NCVFAPADV 65
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNVRGP 460
+E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+ G
Sbjct: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125
Query: 461 YYLTMLAIPHLIKT-------KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ + L + + +G I+N +SV AY SK I T +A +
Sbjct: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185
Query: 620 VALKGVRVNAVNPGVITTGL 679
+A G+RV + PG+ T L
Sbjct: 186 LAPIGIRVMTIAPGLFGTPL 205
>U26726-1|AAC50356.1| 405|Homo sapiens 11-beta-hydroxysteroid
dehydrogenase type 2 protein.
Length = 405
Score = 63.7 bits (148), Expect = 7e-10
Identities = 52/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A + V+ITG SG G ETA + + ++ T + N E ++ + ++
Sbjct: 81 ATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLEL----NSPGAIELRTCCSPRLRLLQ 136
Query: 290 ADMNNESDVENIIKKTVDNYHQLDV--LVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
D+ D+ +++ T + + LVNNAG E E + +A + M N G
Sbjct: 137 MDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGA 196
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P L ++G IV V S G +P + AY SK+A+ + E+ GV+
Sbjct: 197 LELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVK 256
Query: 641 VNAVNPGVITT 673
V+ + PG T
Sbjct: 257 VSIIQPGCFKT 267
>EF694683-1|ABS29267.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 63.7 bits (148), Expect = 7e-10
Identities = 52/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A + V+ITG SG G ETA + + ++ T + N E ++ + ++
Sbjct: 81 ATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLEL----NSPGAIELRTCCSPRLRLLQ 136
Query: 290 ADMNNESDVENIIKKTVDNYHQLDV--LVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
D+ D+ +++ T + + LVNNAG E E + +A + M N G
Sbjct: 137 MDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGA 196
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P L ++G IV V S G +P + AY SK+A+ + E+ GV+
Sbjct: 197 LELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVK 256
Query: 641 VNAVNPGVITT 673
V+ + PG T
Sbjct: 257 VSIIQPGCFKT 267
>BC064536-1|AAH64536.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 63.7 bits (148), Expect = 7e-10
Identities = 52/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A + V+ITG SG G ETA + + ++ T + N E ++ + ++
Sbjct: 81 ATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLEL----NSPGAIELRTCCSPRLRLLQ 136
Query: 290 ADMNNESDVENIIKKTVDNYHQLDV--LVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
D+ D+ +++ T + + LVNNAG E E + +A + M N G
Sbjct: 137 MDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGA 196
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P L ++G IV V S G +P + AY SK+A+ + E+ GV+
Sbjct: 197 LELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVK 256
Query: 641 VNAVNPGVITT 673
V+ + PG T
Sbjct: 257 VSIIQPGCFKT 267
>BC036780-1|AAH36780.1| 405|Homo sapiens hydroxysteroid (11-beta)
dehydrogenase 2 protein.
Length = 405
Score = 63.7 bits (148), Expect = 7e-10
Identities = 52/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A + V+ITG SG G ETA + + ++ T + N E ++ + ++
Sbjct: 81 ATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLEL----NSPGAIELRTCCSPRLRLLQ 136
Query: 290 ADMNNESDVENIIKKTVDNYHQLDV--LVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
D+ D+ +++ T + + LVNNAG E E + +A + M N G
Sbjct: 137 MDLTKPGDISRVLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGA 196
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P L ++G IV V S G +P + AY SK+A+ + E+ GV+
Sbjct: 197 LELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVK 256
Query: 641 VNAVNPGVITT 673
V+ + PG T
Sbjct: 257 VSIIQPGCFKT 267
>U14631-1|AAA91969.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase type II protein.
Length = 405
Score = 63.3 bits (147), Expect = 9e-10
Identities = 52/191 (27%), Positives = 86/191 (45%), Gaps = 3/191 (1%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A + V+ITG SG G ETA + + ++ T + N E ++ + ++
Sbjct: 81 ATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLEL----NSPGAIELRTCCSPRLRLLQ 136
Query: 290 ADMNNESDVENIIKKTVDNYHQLDV--LVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
D+ D+ +++ T + + LVNNAG E E + +A + M N G
Sbjct: 137 MDLTKPGDISRLLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGA 196
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P L ++G IV V S G +P + AY SK+A+ + E+ GV+
Sbjct: 197 LELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVK 256
Query: 641 VNAVNPGVITT 673
V+ + PG T
Sbjct: 257 VSIIQPGCFKT 267
>D82061-1|BAA11529.1| 259|Homo sapiens a member of the short-chain
alcohol dehydrogenase family protein.
Length = 259
Score = 63.3 bits (147), Expect = 9e-10
Identities = 45/197 (22%), Positives = 89/197 (45%), Gaps = 7/197 (3%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVL----TGRKKENLDNVASDCESQSPSKIKPLVV 286
+ ++TGA SGIG + A A + +E + + + P +
Sbjct: 11 LALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHAAF 70
Query: 287 VADMNNESDVENIIKKTVDNYHQ-LDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPY 463
AD++ ++++ + + V+V+ AG+ + + S +D+++ N++G +
Sbjct: 71 QADVSEARAARCLLEQVQACFSRPPSVVVSCAGITQDEFLLHMSRDDWDKVIAVNLKGTF 130
Query: 464 YLTMLAIPHLIKT--KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGV 637
+T A L+ +G+I+N+SS+ G Y SK+ + T+ A E+ G+
Sbjct: 131 LVTQAAAQALVSNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGLTQTAARELGRHGI 190
Query: 638 RVNAVNPGVITTGLHKK 688
N+V PG I T + KK
Sbjct: 191 PCNSVLPGFIATPMTKK 207
>U27317-1|AAB48544.1| 405|Homo sapiens 11 beta-hydroxysteroid
dehydrogenase 2 protein.
Length = 405
Score = 62.5 bits (145), Expect = 2e-09
Identities = 52/191 (27%), Positives = 85/191 (44%), Gaps = 3/191 (1%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
A + V+ITG SG G ETA + + ++ T + N E ++ + ++
Sbjct: 81 ATRAVLITGCDSGFGKETAKKLDSMGFTVLATVLEL----NSPGAIELRTCCSPRLRLLQ 136
Query: 290 ADMNNESDVENIIKKTVDNYHQLDV--LVNNAGVLES-GTIETTSLAQYDRIMNTNVRGP 460
D+ D+ ++ T + + LVNNAG E E + +A + M N G
Sbjct: 137 MDLTKPGDISRFLEFTKAHTTSTGLWGLVNNAGHNEVVADAELSPVATFRSCMEVNFFGA 196
Query: 461 YYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVR 640
LT +P L ++G IV V S G +P + AY SK+A+ + E+ GV+
Sbjct: 197 LELTKGLLPLLRSSRGRIVTVGSPAGDMPYPCLGAYGTSKAAVALLMDTFSCELLPWGVK 256
Query: 641 VNAVNPGVITT 673
V+ + PG T
Sbjct: 257 VSIIQPGCFKT 267
>CR457309-1|CAG33590.1| 173|Homo sapiens DHRS6 protein.
Length = 173
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV+I+T A+ GIG A FA+ AK++ T + L + Q+ V D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--------VLD 58
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + ++ + +LDVL N AG + GT+ +D MN NVR Y +
Sbjct: 59 VTKKKQIDQFASEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 476 LAIPHLIKTK-GNIVNVSSV 532
+P ++ K GNI+N+SSV
Sbjct: 115 AFLPKMLAQKSGNIINMSSV 134
>BC037277-1|AAH37277.1| 173|Homo sapiens BDH2 protein protein.
Length = 173
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV+I+T A+ GIG A FA+ AK++ T + L + Q+ V D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--------VLD 58
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + ++ + +LDVL N AG + GT+ +D MN NVR Y +
Sbjct: 59 VTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 476 LAIPHLIKTK-GNIVNVSSV 532
+P ++ K GNI+N+SSV
Sbjct: 115 AFLPKMLAQKSGNIINMSSV 134
>AY358566-1|AAQ88929.1| 377|Homo sapiens EALL419 protein.
Length = 377
Score = 62.5 bits (145), Expect = 2e-09
Identities = 53/203 (26%), Positives = 93/203 (45%), Gaps = 15/203 (7%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
+ ++TGA+SGIG TA E A+ A++VL R +E + A D +S + + + + D
Sbjct: 37 RTAVVTGANSGIGKMTALELARRGARVVLACRSQERGEAAAFDLRQESGNN-EVIFMALD 95
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + V + + +LD+L++NAG+ G ++ ++ N GP+ LT
Sbjct: 96 LASLASVRAFATAFLSSEPRLDILIHNAGISSCGRTREA----FNLLLRVNHIGPFLLTH 151
Query: 476 LAIPHL-IKTKGNIVNVSSVTGLRS--------------FPNVLAYCISKSAIDQFTRCV 610
L +P L +V V+S R + AY +K A F R +
Sbjct: 152 LLLPCLKACAPSRVVVVASAAHCRGRLDFKRLDRPVVGWRQELRAYADTKLANVLFAREL 211
Query: 611 ALEVALKGVRVNAVNPGVITTGL 679
A ++ GV A +PG + + L
Sbjct: 212 ANQLEATGVTCYAAHPGPVNSEL 234
>AK023323-1|BAB14526.1| 173|Homo sapiens protein ( Homo sapiens
cDNA FLJ13261 fis, clone OVARC1000885, weakly similar to
OXIDOREDUCTASE UCPA (EC 1.-.-.-). ).
Length = 173
Score = 62.5 bits (145), Expect = 2e-09
Identities = 43/140 (30%), Positives = 67/140 (47%), Gaps = 1/140 (0%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV+I+T A+ GIG A FA+ AK++ T + L + Q+ V D
Sbjct: 7 KVIILTAAAQGIGQAAALAFAREGAKVIATDINESKLQELEKYPGIQTR--------VLD 58
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + ++ + +LDVL N AG + GT+ +D MN NVR Y +
Sbjct: 59 VTKKKQIDQFANEV----ERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLMIK 114
Query: 476 LAIPHLIKTK-GNIVNVSSV 532
+P ++ K GNI+N+SSV
Sbjct: 115 AFLPKMLAQKSGNIINMSSV 134
>BC101553-1|AAI01554.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 60.9 bits (141), Expect = 5e-09
Identities = 50/191 (26%), Positives = 90/191 (47%), Gaps = 1/191 (0%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
+ K V ITG SG G A + +++ +E + D + + + L V
Sbjct: 24 SEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTL--LDVT 81
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVRGPYY 466
+ ++ + + K + L LVNNAGV L SG E + + +++N N+ G
Sbjct: 82 KSESIKAAAQWVRDKVGEQ--GLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T+ +P + + +G +VN+SS +G R YC+SK ++ F+ + E+ GV+V
Sbjct: 140 VTLHMLPMVKRARGRVVNMSS-SGGRVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVC 198
Query: 647 AVNPGVITTGL 679
+ PG T +
Sbjct: 199 IIEPGNYRTAI 209
>BC101551-1|AAI01552.1| 313|Homo sapiens orphan short-chain
dehydrogenase / reductase protein.
Length = 313
Score = 60.9 bits (141), Expect = 5e-09
Identities = 50/191 (26%), Positives = 90/191 (47%), Gaps = 1/191 (0%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
+ K V ITG SG G A + +++ +E + D + + + L V
Sbjct: 24 SEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTL--LDVT 81
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVRGPYY 466
+ ++ + + K + L LVNNAGV L SG E + + +++N N+ G
Sbjct: 82 KSESIKAAAQWVRDKVGEQ--GLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T+ +P + + +G +VN+SS +G R YC+SK ++ F+ + E+ GV+V
Sbjct: 140 VTLHMLPMVKRARGRVVNMSS-SGGRVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVC 198
Query: 647 AVNPGVITTGL 679
+ PG T +
Sbjct: 199 IIEPGNYRTAI 209
>AY044434-1|AAK95856.1| 313|Homo sapiens retinol dehydrogenase
similar protein protein.
Length = 313
Score = 60.9 bits (141), Expect = 5e-09
Identities = 50/191 (26%), Positives = 90/191 (47%), Gaps = 1/191 (0%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
+ K V ITG SG G A + +++ +E + D + + + L V
Sbjct: 24 SEKYVFITGCDSGFGNLLAKQLVDRGMQVLAACFTEEGSQKLQRDTSYRLQTTL--LDVT 81
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVRGPYY 466
+ ++ + + K + L LVNNAGV L SG E + + +++N N+ G
Sbjct: 82 KSESIKAAAQWVRDKVGEQ--GLWALVNNAGVGLPSGPNEWLTKDDFVKVINVNLVGLIE 139
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T+ +P + + +G +VN+SS +G R YC+SK ++ F+ + E+ GV+V
Sbjct: 140 VTLHMLPMVKRARGRVVNMSS-SGGRVAVIGGGYCVSKFGVEAFSDSIRRELYYFGVKVC 198
Query: 647 AVNPGVITTGL 679
+ PG T +
Sbjct: 199 IIEPGNYRTAI 209
>BC032340-1|AAH32340.1| 330|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 330
Score = 60.1 bits (139), Expect = 9e-09
Identities = 57/210 (27%), Positives = 95/210 (45%), Gaps = 19/210 (9%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
++V I+TG + GIG TA A+L +++ G V S + ++ + K +
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYC 101
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ + + + ++K L VL+NNAGV+ +T ++ N G + LT
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRD--GFEEHFGLNYLGHFLLT 159
Query: 473 MLAIPHLIKT-----KGNIVNVSSVT---------GLRS---FPNVLAYCISKSAIDQFT 601
L + L ++ +V VSS T L+S + AY SK A+ FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 602 RCVALEVALKG--VRVNAVNPGVITTGLHK 685
+ +A +G V N V+PGV+ T L+K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDLYK 249
>AJ293620-1|CAC82170.1| 330|Homo sapiens putative oxidoreductase
protein.
Length = 330
Score = 60.1 bits (139), Expect = 9e-09
Identities = 57/210 (27%), Positives = 95/210 (45%), Gaps = 19/210 (9%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
++V I+TG + GIG TA A+L +++ G V S + ++ + K +
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYC 101
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ + + + ++K L VL+NNAGV+ +T ++ N G + LT
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRD--GFEEHFGLNYLGHFLLT 159
Query: 473 MLAIPHLIKT-----KGNIVNVSSVT---------GLRS---FPNVLAYCISKSAIDQFT 601
L + L ++ +V VSS T L+S + AY SK A+ FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 602 RCVALEVALKG--VRVNAVNPGVITTGLHK 685
+ +A +G V N V+PGV+ T L+K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDLYK 249
>BC067131-1|AAH67131.1| 341|Homo sapiens retinol dehydrogenase 10
(all-trans) protein.
Length = 341
Score = 59.7 bits (138), Expect = 1e-08
Identities = 61/233 (26%), Positives = 101/233 (43%), Gaps = 26/233 (11%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVAS-------DCESQSPSK 268
A +V +ITGA SG+G A EFA+ A LVL ++ + A D E+ +
Sbjct: 35 AGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAA 94
Query: 269 IKP---------------LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI 403
++ D+ +V ++ ++ VLVNNAGV+ +
Sbjct: 95 LQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHL 154
Query: 404 ETTSLAQYDRIMNTNVRGPYYLTMLAIPHLIK-TKGNIVNVSSVTGLRSFPNVLAYCISK 580
+R M N ++ T +P +++ G+IV V+S GL S V YC SK
Sbjct: 155 LECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASK 214
Query: 581 SAIDQFTRCVA--LEVALK-GVRVNAVNPGVITTGLHKKGEGSMNEEQYEAFL 730
+ F ++ L+ A K G++ V P ++ TG+ + G ++ E FL
Sbjct: 215 FGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFR---GCRIRKEIEPFL 264
>AY358270-1|AAQ88637.1| 341|Homo sapiens RDH10 protein.
Length = 341
Score = 59.7 bits (138), Expect = 1e-08
Identities = 61/233 (26%), Positives = 101/233 (43%), Gaps = 26/233 (11%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVAS-------DCESQSPSK 268
A +V +ITGA SG+G A EFA+ A LVL ++ + A D E+ +
Sbjct: 35 AGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAA 94
Query: 269 IKP---------------LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI 403
++ D+ +V ++ ++ VLVNNAGV+ +
Sbjct: 95 LQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHL 154
Query: 404 ETTSLAQYDRIMNTNVRGPYYLTMLAIPHLIK-TKGNIVNVSSVTGLRSFPNVLAYCISK 580
+R M N ++ T +P +++ G+IV V+S GL S V YC SK
Sbjct: 155 LECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASK 214
Query: 581 SAIDQFTRCVA--LEVALK-GVRVNAVNPGVITTGLHKKGEGSMNEEQYEAFL 730
+ F ++ L+ A K G++ V P ++ TG+ + G ++ E FL
Sbjct: 215 FGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFR---GCRIRKEIEPFL 264
>AF456765-1|AAN64747.1| 341|Homo sapiens retinol dehydrogenase 10
protein.
Length = 341
Score = 59.7 bits (138), Expect = 1e-08
Identities = 61/233 (26%), Positives = 101/233 (43%), Gaps = 26/233 (11%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVAS-------DCESQSPSK 268
A +V +ITGA SG+G A EFA+ A LVL ++ + A D E+ +
Sbjct: 35 AGQVCLITGAGSGLGRLFALEFARRRALLVLWDINTQSNEETAGMVRHIYRDLEAADAAA 94
Query: 269 IKP---------------LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI 403
++ D+ +V ++ ++ VLVNNAGV+ +
Sbjct: 95 LQAGNGEEEILPHCNLQVFTYTCDVGKRENVYLTAERVRKEVGEVSVLVNNAGVVSGHHL 154
Query: 404 ETTSLAQYDRIMNTNVRGPYYLTMLAIPHLIK-TKGNIVNVSSVTGLRSFPNVLAYCISK 580
+R M N ++ T +P +++ G+IV V+S GL S V YC SK
Sbjct: 155 LECPDELIERTMMVNCHAHFWTTKAFLPTMLEINHGHIVTVASSLGLFSTAGVEDYCASK 214
Query: 581 SAIDQFTRCVA--LEVALK-GVRVNAVNPGVITTGLHKKGEGSMNEEQYEAFL 730
+ F ++ L+ A K G++ V P ++ TG+ + G ++ E FL
Sbjct: 215 FGVVGFHESLSHELKAAEKDGIKTTLVCPYLVDTGMFR---GCRIRKEIEPFL 264
>DQ426886-1|ABD90542.1| 171|Homo sapiens retinol dehydrogenase 11
protein.
Length = 171
Score = 59.3 bits (137), Expect = 2e-08
Identities = 40/132 (30%), Positives = 68/132 (51%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
T KVV++TGA++GIG ETA E A+ A++ L R E + VA + ++ + ++ +
Sbjct: 36 TVQLPGKVVVVTGANTGIGKETAKELAQRGARVYLACRDVEKGELVAKEIQTTTGNQ-QV 94
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
LV D+++ + K + L VL+NNAGV+ +T ++ + N G
Sbjct: 95 LVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLG 152
Query: 458 PYYLTMLAIPHL 493
+ LT L + L
Sbjct: 153 HFLLTHLLLEKL 164
>AK027882-1|BAB55429.1| 177|Homo sapiens protein ( Homo sapiens
cDNA FLJ14976 fis, clone THYRO1001406, highly similar to
PUTATIVE STEROID DEHYDROGENASE KIK-I (EC 1.1.1.-). ).
Length = 177
Score = 59.3 bits (137), Expect = 2e-08
Identities = 32/110 (29%), Positives = 62/110 (56%), Gaps = 1/110 (0%)
Frame = +2
Query: 431 RIMNTNVRGPYYLTMLAIPHLI-KTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRC 607
+++N N+ +T L +P ++ ++KG I+N+SS +G+ P + Y +K+ +D F++C
Sbjct: 21 KMININILSVCKMTQLVLPGMVERSKGAILNISSGSGMLPVPLLTIYSATKTFVDFFSQC 80
Query: 608 VALEVALKGVRVNAVNPGVITTGLHKKGEGSMNEEQYEAFLAKCAETHAL 757
+ E KGV V +V P + T L K + ++++ E F+ +T L
Sbjct: 81 LHEEYRSKGVFVQSVLPYFVATKLAKIRKPTLDKPSPETFVKSAIKTVGL 130
>CR381696-2|CAI95410.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 58.8 bits (136), Expect = 2e-08
Identities = 56/210 (26%), Positives = 95/210 (45%), Gaps = 19/210 (9%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
++V I+TG + GIG TA A+L +++ G V S + ++ + K +
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYC 101
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ + + + ++K L VL+NNAGV+ +T ++ N G + LT
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRD--GFEEHFGLNYLGHFLLT 159
Query: 473 MLAIPHLIKT-----KGNIVNVSSVT---------GLRS---FPNVLAYCISKSAIDQFT 601
L + L ++ +V VSS T L+S + AY SK A+ FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 602 RCVALEVALKG--VRVNAVNPGVITTGLHK 685
+ +A +G V N V+PGV+ T ++K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVYK 249
>BX649443-2|CAI95431.1| 268|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 268
Score = 58.8 bits (136), Expect = 2e-08
Identities = 56/210 (26%), Positives = 95/210 (45%), Gaps = 19/210 (9%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
++V I+TG + GIG TA A+L +++ G V S + ++ + K +
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYC 101
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ + + + ++K L VL+NNAGV+ +T ++ N G + LT
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRD--GFEEHFGLNYLGHFLLT 159
Query: 473 MLAIPHLIKT-----KGNIVNVSSVT---------GLRS---FPNVLAYCISKSAIDQFT 601
L + L ++ +V VSS T L+S + AY SK A+ FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 602 RCVALEVALKG--VRVNAVNPGVITTGLHK 685
+ +A +G V N V+PGV+ T ++K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVYK 249
>BC058883-1|AAH58883.1| 319|Homo sapiens dehydrogenase/reductase
(SDR family) member 9 protein.
Length = 319
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
E +K + ITG SG G A F K ++ + ++ ++++ +++ +
Sbjct: 25 EDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTV 80
Query: 281 VV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT---SLAQYDRIMNTN 448
++ V D N +K V L L+NNAGV G + T +L Y + N
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGE-KGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEVN 137
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T+ +P + K +G ++NVSSV G + Y SK A++ F + ++
Sbjct: 138 LFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMKA 196
Query: 629 KGVRVNAVNPGVITTGL 679
GV V+ + PG+ T L
Sbjct: 197 FGVHVSCIEPGLFKTNL 213
>BC019696-1|AAH19696.2| 330|Homo sapiens DHRSX protein protein.
Length = 330
Score = 58.8 bits (136), Expect = 2e-08
Identities = 56/210 (26%), Positives = 95/210 (45%), Gaps = 19/210 (9%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
++V I+TG + GIG TA A+L +++ G V S + ++ + K +
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYC 101
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ + + + ++K L VL+NNAGV+ +T ++ N G + LT
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRD--GFEEHFGLNYLGHFLLT 159
Query: 473 MLAIPHLIKT-----KGNIVNVSSVT---------GLRS---FPNVLAYCISKSAIDQFT 601
L + L ++ +V VSS T L+S + AY SK A+ FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 602 RCVALEVALKG--VRVNAVNPGVITTGLHK 685
+ +A +G V N V+PGV+ T ++K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVYK 249
>BC009830-1|AAH09830.1| 336|Homo sapiens retinol dehydrogenase 14
(all-trans/9-cis/11-cis) protein.
Length = 336
Score = 58.8 bits (136), Expect = 2e-08
Identities = 59/214 (27%), Positives = 100/214 (46%), Gaps = 26/214 (12%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNV----------ASDCESQ-SP 262
K V+ITGA+SG+G TA E +L A++++ R + + A++C +
Sbjct: 44 KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGV 103
Query: 263 SKIKPLVV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIM 439
S + L+V D+ + V ++ + +LDVL+NNAG+ + ++T ++
Sbjct: 104 SGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQF 161
Query: 440 NTNVRGPYYLTMLAIPHLIKTK--GNIVNVSS------------VTGLRSFPNVLAYCIS 577
N G + LT L + L+K+ IV VSS + +S+ Y S
Sbjct: 162 GVNHLGHFLLTNLLL-GLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRS 220
Query: 578 KSAIDQFTRCVALEVALKGVRVNAVNPGVITTGL 679
K A FTR +A + V VN ++PG++ T L
Sbjct: 221 KLANILFTRELARRLEGTNVTVNVLHPGIVRTNL 254
>AY359046-1|AAQ89405.1| 319|Homo sapiens RDHL protein.
Length = 319
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
E +K + ITG SG G A F K ++ + ++ ++++ +++ +
Sbjct: 25 EDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTV 80
Query: 281 VV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT---SLAQYDRIMNTN 448
++ V D N +K V L L+NNAGV G + T +L Y + N
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGE-KGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEVN 137
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T+ +P + K +G ++NVSSV G + Y SK A++ F + ++
Sbjct: 138 LFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMKA 196
Query: 629 KGVRVNAVNPGVITTGL 679
GV V+ + PG+ T L
Sbjct: 197 FGVHVSCIEPGLFKTNL 213
>AY358849-1|AAQ89208.1| 330|Homo sapiens ALTE protein.
Length = 330
Score = 58.8 bits (136), Expect = 2e-08
Identities = 56/210 (26%), Positives = 95/210 (45%), Gaps = 19/210 (9%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
++V I+TG + GIG TA A+L +++ G V S + ++ + K +
Sbjct: 43 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYC 101
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ + + + ++K L VL+NNAGV+ +T ++ N G + LT
Sbjct: 102 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRD--GFEEHFGLNYLGHFLLT 159
Query: 473 MLAIPHLIKT-----KGNIVNVSSVT---------GLRS---FPNVLAYCISKSAIDQFT 601
L + L ++ +V VSS T L+S + AY SK A+ FT
Sbjct: 160 NLLLDTLKESGSPGHSARVVTVSSATHYVAELNMDDLQSSACYSPHAAYAQSKLALVLFT 219
Query: 602 RCVALEVALKG--VRVNAVNPGVITTGLHK 685
+ +A +G V N V+PGV+ T ++K
Sbjct: 220 YHLQRLLAAEGSHVTANVVDPGVVNTDVYK 249
>AY358511-1|AAQ88875.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 58.8 bits (136), Expect = 2e-08
Identities = 59/214 (27%), Positives = 100/214 (46%), Gaps = 26/214 (12%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNV----------ASDCESQ-SP 262
K V+ITGA+SG+G TA E +L A++++ R + + A++C +
Sbjct: 44 KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGV 103
Query: 263 SKIKPLVV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIM 439
S + L+V D+ + V ++ + +LDVL+NNAG+ + ++T ++
Sbjct: 104 SGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQF 161
Query: 440 NTNVRGPYYLTMLAIPHLIKTK--GNIVNVSS------------VTGLRSFPNVLAYCIS 577
N G + LT L + L+K+ IV VSS + +S+ Y S
Sbjct: 162 GVNHLGHFLLTNLLL-GLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRS 220
Query: 578 KSAIDQFTRCVALEVALKGVRVNAVNPGVITTGL 679
K A FTR +A + V VN ++PG++ T L
Sbjct: 221 KLANILFTRELARRLEGTNVTVNVLHPGIVRTNL 254
>AY017349-1|AAG49422.1| 319|Homo sapiens retinol dehydrogenase
protein.
Length = 319
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
E +K + ITG SG G A F K ++ + ++ ++++ +++ +
Sbjct: 25 EDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTV 80
Query: 281 VV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT---SLAQYDRIMNTN 448
++ V D N +K V L L+NNAGV G + T +L Y + N
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGE-KGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEVN 137
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T+ +P + K +G ++NVSSV G + Y SK A++ F + ++
Sbjct: 138 LFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMKA 196
Query: 629 KGVRVNAVNPGVITTGL 679
GV V+ + PG+ T L
Sbjct: 197 FGVHVSCIEPGLFKTNL 213
>AF529288-1|AAN04010.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript A protein.
Length = 319
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
E +K + ITG SG G A F K ++ + ++ ++++ +++ +
Sbjct: 25 EDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTV 80
Query: 281 VV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT---SLAQYDRIMNTN 448
++ V D N +K V L L+NNAGV G + T +L Y + N
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGE-KGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEVN 137
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T+ +P + K +G ++NVSSV G + Y SK A++ F + ++
Sbjct: 138 LFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMKA 196
Query: 629 KGVRVNAVNPGVITTGL 679
GV V+ + PG+ T L
Sbjct: 197 FGVHVSCIEPGLFKTNL 213
>AF529287-1|AAN04009.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript B protein.
Length = 319
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
E +K + ITG SG G A F K ++ + ++ ++++ +++ +
Sbjct: 25 EDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTV 80
Query: 281 VV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT---SLAQYDRIMNTN 448
++ V D N +K V L L+NNAGV G + T +L Y + N
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGE-KGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEVN 137
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T+ +P + K +G ++NVSSV G + Y SK A++ F + ++
Sbjct: 138 LFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMKA 196
Query: 629 KGVRVNAVNPGVITTGL 679
GV V+ + PG+ T L
Sbjct: 197 FGVHVSCIEPGLFKTNL 213
>AF529286-1|AAN04008.1| 319|Homo sapiens microsomal NADP-dependent
retinol dehydrogenase/reductase transcript C protein.
Length = 319
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
E +K + ITG SG G A F K ++ + ++ ++++ +++ +
Sbjct: 25 EDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTV 80
Query: 281 VV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT---SLAQYDRIMNTN 448
++ V D N +K V L L+NNAGV G + T +L Y + N
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGE-KGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEVN 137
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T+ +P + K +G ++NVSSV G + Y SK A++ F + ++
Sbjct: 138 LFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMKA 196
Query: 629 KGVRVNAVNPGVITTGL 679
GV V+ + PG+ T L
Sbjct: 197 FGVHVSCIEPGLFKTNL 213
>AF343729-1|AAK37528.1| 319|Homo sapiens 3-alpha hydroxysteroid
dehydrogenase protein.
Length = 319
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
E +K + ITG SG G A F K ++ + ++ ++++ +++ +
Sbjct: 25 EDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTV 80
Query: 281 VV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT---SLAQYDRIMNTN 448
++ V D N +K V L L+NNAGV G + T +L Y + N
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGE-KGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEVN 137
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T+ +P + K +G ++NVSSV G + Y SK A++ F + ++
Sbjct: 138 LFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMKA 196
Query: 629 KGVRVNAVNPGVITTGL 679
GV V+ + PG+ T L
Sbjct: 197 FGVHVSCIEPGLFKTNL 213
>AF295380-1|AAL37037.1| 319|Homo sapiens short-chain
dehydrogenase/reductase RETSDR8 protein.
Length = 319
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
E +K + ITG SG G A F K ++ + ++ ++++ +++ +
Sbjct: 25 EDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTV 80
Query: 281 VV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT---SLAQYDRIMNTN 448
++ V D N +K V L L+NNAGV G + T +L Y + N
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGE-KGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEVN 137
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T+ +P + K +G ++NVSSV G + Y SK A++ F + ++
Sbjct: 138 LFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMKA 196
Query: 629 KGVRVNAVNPGVITTGL 679
GV V+ + PG+ T L
Sbjct: 197 FGVHVSCIEPGLFKTNL 213
>AF237952-1|AAG12190.1| 336|Homo sapiens PAN2 protein.
Length = 336
Score = 58.8 bits (136), Expect = 2e-08
Identities = 59/214 (27%), Positives = 100/214 (46%), Gaps = 26/214 (12%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNV----------ASDCESQ-SP 262
K V+ITGA+SG+G TA E +L A++++ R + + A++C +
Sbjct: 44 KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGV 103
Query: 263 SKIKPLVV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIM 439
S + L+V D+ + V ++ + +LDVL+NNAG+ + ++T ++
Sbjct: 104 SGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQF 161
Query: 440 NTNVRGPYYLTMLAIPHLIKTK--GNIVNVSS------------VTGLRSFPNVLAYCIS 577
N G + LT L + L+K+ IV VSS + +S+ Y S
Sbjct: 162 GVNHLGHFLLTNLLL-GLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRS 220
Query: 578 KSAIDQFTRCVALEVALKGVRVNAVNPGVITTGL 679
K A FTR +A + V VN ++PG++ T L
Sbjct: 221 KLANILFTRELARRLEGTNVTVNVLHPGIVRTNL 254
>AF086735-1|AAC72923.1| 317|Homo sapiens retinol dehydrogenase
protein.
Length = 317
Score = 58.8 bits (136), Expect = 2e-08
Identities = 50/194 (25%), Positives = 90/194 (46%), Gaps = 2/194 (1%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVV-V 289
+K V ITG SG G A + +++ ++ A Q+ +++ + + V
Sbjct: 29 DKYVFITGCDSGFGKLLARQLDARGLRVLAACLTEKG----AEQLRGQTSDRLETVTLDV 84
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTIETTSLAQYDRIMNTNVRGPYY 466
+ + +K+ V + L LVNNAG+ L + E + I++ N+ G
Sbjct: 85 TKTESVAAAAQWVKECVRD-KGLWGLVNNAGISLPTAPNELLTKQDLLTILDVNLLGVID 143
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T+ +P + + +G +VNV SV G S YCISK ++ F+ + E++ GV+V
Sbjct: 144 VTLNLLPLVRRARGRVVNVFSVMGRVSLFGG-GYCISKYGVEAFSDSLRRELSYFGVKVA 202
Query: 647 AVNPGVITTGLHKK 688
+ PG T + K
Sbjct: 203 MIEPGYFKTAVTSK 216
>AC079148-1|AAX93259.1| 336|Homo sapiens unknown protein.
Length = 336
Score = 58.8 bits (136), Expect = 2e-08
Identities = 59/214 (27%), Positives = 100/214 (46%), Gaps = 26/214 (12%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNV----------ASDCESQ-SP 262
K V+ITGA+SG+G TA E +L A++++ R + + A++C +
Sbjct: 44 KTVLITGANSGLGRATAAELLRLGARVIMGCRDRARAEEAAGQLRRELRQAAECGPEPGV 103
Query: 263 SKIKPLVV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIM 439
S + L+V D+ + V ++ + +LDVL+NNAG+ + ++T ++
Sbjct: 104 SGVGELIVRELDLASLRSVRAFCQEMLQEEPRLDVLINNAGIFQCPYMKTED--GFEMQF 161
Query: 440 NTNVRGPYYLTMLAIPHLIKTK--GNIVNVSS------------VTGLRSFPNVLAYCIS 577
N G + LT L + L+K+ IV VSS + +S+ Y S
Sbjct: 162 GVNHLGHFLLTNLLL-GLLKSSAPSRIVVVSSKLYKYGDINFDDLNSEQSYNKSFCYSRS 220
Query: 578 KSAIDQFTRCVALEVALKGVRVNAVNPGVITTGL 679
K A FTR +A + V VN ++PG++ T L
Sbjct: 221 KLANILFTRELARRLEGTNVTVNVLHPGIVRTNL 254
>AC008177-2|AAY24306.1| 245|Homo sapiens unknown protein.
Length = 245
Score = 58.8 bits (136), Expect = 2e-08
Identities = 51/197 (25%), Positives = 90/197 (45%), Gaps = 4/197 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
E +K + ITG SG G A F K ++ + ++ ++++ +++ +
Sbjct: 25 EDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTV 80
Query: 281 VV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT---SLAQYDRIMNTN 448
++ V D N +K V L L+NNAGV G + T +L Y + N
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGE-KGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEVN 137
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T+ +P + K +G ++NVSSV G + Y SK A++ F + ++
Sbjct: 138 LFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMKA 196
Query: 629 KGVRVNAVNPGVITTGL 679
GV V+ + PG+ T L
Sbjct: 197 FGVHVSCIEPGLFKTNL 213
>X13440-1|CAA31792.1| 328|Homo sapiens protein ( Human mRNA for
17-beta-hydroxysteroid dehydrogenase (17-HSD) (EC
1.1.1.62). ).
Length = 328
Score = 58.4 bits (135), Expect = 3e-08
Identities = 54/206 (26%), Positives = 92/206 (44%), Gaps = 6/206 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFA---KLNAKLVLTGRKKENLDNV--ASDCESQSPSKIK 274
A VV+ITG SSGIG A A + K+ T R + + A+ + P ++
Sbjct: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVR 454
L + D+ + V ++ + ++DVLV NAG+ G +E +++ NV
Sbjct: 62 TLQL--DVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117
Query: 455 GPYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
G + +P + + G ++ SV GL P YC SK A++ +A+ +
Sbjct: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 632 GVRVNAVNPGVITTGLHKKGEGSMNE 709
GV ++ + G + T +K GS E
Sbjct: 178 GVHLSLIECGPVHTAFMEKVLGSPEE 203
>U34879-1|AAD05019.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 58.4 bits (135), Expect = 3e-08
Identities = 54/206 (26%), Positives = 92/206 (44%), Gaps = 6/206 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFA---KLNAKLVLTGRKKENLDNV--ASDCESQSPSKIK 274
A VV+ITG SSGIG A A + K+ T R + + A+ + P ++
Sbjct: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVR 454
L + D+ + V ++ + ++DVLV NAG+ G +E +++ NV
Sbjct: 62 TLQL--DVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117
Query: 455 GPYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
G + +P + + G ++ SV GL P YC SK A++ +A+ +
Sbjct: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 632 GVRVNAVNPGVITTGLHKKGEGSMNE 709
GV ++ + G + T +K GS E
Sbjct: 178 GVHLSLIECGPVHTAFMEKVLGSPEE 203
>M84472-1|AAB16942.1| 328|Homo sapiens 17-beta-hydroxysteroid
dehydrogenase protein.
Length = 328
Score = 58.4 bits (135), Expect = 3e-08
Identities = 54/206 (26%), Positives = 92/206 (44%), Gaps = 6/206 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFA---KLNAKLVLTGRKKENLDNV--ASDCESQSPSKIK 274
A VV+ITG SSGIG A A + K+ T R + + A+ + P ++
Sbjct: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVR 454
L + D+ + V ++ + ++DVLV NAG+ G +E +++ NV
Sbjct: 62 TLQL--DVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117
Query: 455 GPYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
G + +P + + G ++ SV GL P YC SK A++ +A+ +
Sbjct: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 632 GVRVNAVNPGVITTGLHKKGEGSMNE 709
GV ++ + G + T +K GS E
Sbjct: 178 GVHLSLIECGPVHTAFMEKVLGSPEE 203
>M36263-1|AAA35600.1| 328|Homo sapiens protein ( Human placental
17-beta-hydroxysteroid dehydrogenase mRNA, complete cds.
).
Length = 328
Score = 58.4 bits (135), Expect = 3e-08
Identities = 54/206 (26%), Positives = 92/206 (44%), Gaps = 6/206 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFA---KLNAKLVLTGRKKENLDNV--ASDCESQSPSKIK 274
A VV+ITG SSGIG A A + K+ T R + + A+ + P ++
Sbjct: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVR 454
L + D+ + V ++ + ++DVLV NAG+ G +E +++ NV
Sbjct: 62 TLQL--DVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117
Query: 455 GPYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
G + +P + + G ++ SV GL P YC SK A++ +A+ +
Sbjct: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 632 GVRVNAVNPGVITTGLHKKGEGSMNE 709
GV ++ + G + T +K GS E
Sbjct: 178 GVHLSLIECGPVHTAFMEKVLGSPEE 203
>M27138-1|AAB16941.1| 328|Homo sapiens protein ( Human estradiol 17
beta-dehydrogenase gene, complete cds. ).
Length = 328
Score = 58.4 bits (135), Expect = 3e-08
Identities = 54/206 (26%), Positives = 92/206 (44%), Gaps = 6/206 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFA---KLNAKLVLTGRKKENLDNV--ASDCESQSPSKIK 274
A VV+ITG SSGIG A A + K+ T R + + A+ + P ++
Sbjct: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVR 454
L + D+ + V ++ + ++DVLV NAG+ G +E +++ NV
Sbjct: 62 TLQL--DVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117
Query: 455 GPYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
G + +P + + G ++ SV GL P YC SK A++ +A+ +
Sbjct: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 632 GVRVNAVNPGVITTGLHKKGEGSMNE 709
GV ++ + G + T +K GS E
Sbjct: 178 GVHLSLIECGPVHTAFMEKVLGSPEE 203
>BC111935-1|AAI11936.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 58.4 bits (135), Expect = 3e-08
Identities = 54/206 (26%), Positives = 92/206 (44%), Gaps = 6/206 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFA---KLNAKLVLTGRKKENLDNV--ASDCESQSPSKIK 274
A VV+ITG SSGIG A A + K+ T R + + A+ + P ++
Sbjct: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVR 454
L + D+ + V ++ + ++DVLV NAG+ G +E +++ NV
Sbjct: 62 TLQL--DVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117
Query: 455 GPYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
G + +P + + G ++ SV GL P YC SK A++ +A+ +
Sbjct: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 632 GVRVNAVNPGVITTGLHKKGEGSMNE 709
GV ++ + G + T +K GS E
Sbjct: 178 GVHLSLIECGPVHTAFMEKVLGSPEE 203
>BC104752-1|AAI04753.1| 328|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 1 protein.
Length = 328
Score = 58.4 bits (135), Expect = 3e-08
Identities = 54/206 (26%), Positives = 92/206 (44%), Gaps = 6/206 (2%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFA---KLNAKLVLTGRKKENLDNV--ASDCESQSPSKIK 274
A VV+ITG SSGIG A A + K+ T R + + A+ + P ++
Sbjct: 2 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 61
Query: 275 PLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVR 454
L + D+ + V ++ + ++DVLV NAG+ G +E +++ NV
Sbjct: 62 TLQL--DVRDSKSVAAARERVTEG--RVDVLVCNAGLGLLGPLEALGEDAVASVLDVNVV 117
Query: 455 GPYYLTMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALK 631
G + +P + + G ++ SV GL P YC SK A++ +A+ +
Sbjct: 118 GTVRMLQAFLPDMKRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESLAVLLLPF 177
Query: 632 GVRVNAVNPGVITTGLHKKGEGSMNE 709
GV ++ + G + T +K GS E
Sbjct: 178 GVHLSLIECGPVHTAFMEKVLGSPEE 203
>DQ325464-1|ABC61320.1| 244|Homo sapiens NADP(H)-dependent retinol
dehydrogenase/reductase B1 isoform protein.
Length = 244
Score = 57.2 bits (132), Expect = 6e-08
Identities = 42/149 (28%), Positives = 75/149 (50%), Gaps = 6/149 (4%)
Frame = +2
Query: 344 NYHQLDVLVNNAGVLESGTIETTSLAQ-YDRIMNT----NVRGPYYLTMLAIPHLIKTKG 508
N Q + G+ +GT+ A+ +R++ T NV+ P +T +P + K G
Sbjct: 68 NVDQAVATLQGEGLSVTGTVCHVGKAEDRERLVATTLDINVKAPALMTKAVVPEMEKRGG 127
Query: 509 -NIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVNAVNPGVITTGLHK 685
++V VSS+ P Y +SK+A+ T+ +A+E+A + +RVN + PG+I T +
Sbjct: 128 GSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSR 187
Query: 686 KGEGSMNEEQYEAFLAKCAETHALGRPGD 772
M++E+ E+ + + LG P D
Sbjct: 188 M--LWMDKEKEES-MKETLRIRRLGEPED 213
Score = 42.3 bits (95), Expect = 0.002
Identities = 25/94 (26%), Positives = 46/94 (48%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
ANKV ++T ++ GIG A A+ A +V++ RK++N+D + + + + V
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 87
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLE 391
+ D E ++ T+D + L+ A V E
Sbjct: 88 CHVGKAEDRERLVATTLDINVKAPALMTKAVVPE 121
>M76231-1|AAA60314.1| 261|Homo sapiens sepiapterin reductase
protein.
Length = 261
Score = 56.0 bits (129), Expect = 1e-07
Identities = 55/202 (27%), Positives = 92/202 (45%), Gaps = 13/202 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL---NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
V ++TGAS G G A A L + LVL+ R E L + ++ ++ S ++ + V
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAER-SGLRVVRVP 67
Query: 290 ADMNNESDVENIIKKTVDNYH----QLDVLVNNAGVL---ESGTIETTSLAQYDRIMNTN 448
AD+ E+ ++ ++ + Q +L+NNAG L G ++ + Q + N
Sbjct: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127
Query: 449 VRGPYYLT---MLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ LT + A P +VN+SS+ L+ F YC K+A D + +ALE
Sbjct: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187
Query: 620 VALKGVRVNAVNPGVITTGLHK 685
VRV PG + T + +
Sbjct: 188 E--PNVRVLNYAPGPLDTDMQQ 207
>BC017310-1|AAH17310.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) protein.
Length = 261
Score = 56.0 bits (129), Expect = 1e-07
Identities = 55/202 (27%), Positives = 92/202 (45%), Gaps = 13/202 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL---NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
V ++TGAS G G A A L + LVL+ R E L + ++ ++ S ++ + V
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAER-SGLRVVRVP 67
Query: 290 ADMNNESDVENIIKKTVDNYH----QLDVLVNNAGVL---ESGTIETTSLAQYDRIMNTN 448
AD+ E+ ++ ++ + Q +L+NNAG L G ++ + Q + N
Sbjct: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127
Query: 449 VRGPYYLT---MLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ LT + A P +VN+SS+ L+ F YC K+A D + +ALE
Sbjct: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187
Query: 620 VALKGVRVNAVNPGVITTGLHK 685
VRV PG + T + +
Sbjct: 188 E--PNVRVLNYAPGPLDTDMQQ 207
>AK222942-1|BAD96662.1| 261|Homo sapiens sepiapterin reductase
(7,8-dihydrobiopterin:NADP+ oxidoreductase) variant
protein.
Length = 261
Score = 55.2 bits (127), Expect = 2e-07
Identities = 55/202 (27%), Positives = 92/202 (45%), Gaps = 13/202 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL---NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
V ++TGAS G G A A L + LVL+ R E L + ++ ++ S ++ + V
Sbjct: 9 VRLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAER-SGLRVVRVP 67
Query: 290 ADMNNESDVENIIKKTVDNYH----QLDVLVNNAGVL---ESGTIETTSLAQYDRIMNTN 448
AD+ E+ ++ ++ + Q +L+NNAG L G ++ + Q + N
Sbjct: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127
Query: 449 VRGPYYLT---MLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ LT + A P +VN+SS+ L+ F YC K+A D + +ALE
Sbjct: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187
Query: 620 VALKGVRVNAVNPGVITTGLHK 685
VRV PG + T + +
Sbjct: 188 E--PNVRVLNYAPGPLDTDMQQ 207
>U89281-1|AAB88252.1| 317|Homo sapiens oxidative 3 alpha
hydroxysteroid dehydrogenase protein.
Length = 317
Score = 54.8 bits (126), Expect = 3e-07
Identities = 46/191 (24%), Positives = 86/191 (45%), Gaps = 2/191 (1%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVV-V 289
+K V ITG SG G A + +++ D A Q+ +++ + + V
Sbjct: 29 DKYVFITGCDSGFGNLLARQLDARGLRVLAACLT----DKGAEQLRGQTSDRLETVTLDV 84
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTI-ETTSLAQYDRIMNTNVRGPYY 466
M + + +K+ V + +L LVNNAG+L T+ E + ++ N+ G
Sbjct: 85 TKMESIAAATQWVKEHVGD-RRLWGLVNNAGILTPITLCEWLNTEDSMNMLKVNLIGVIQ 143
Query: 467 LTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+T+ +P + + +G +G F YC+SK ++ F+ + E+ GV+++
Sbjct: 144 VTLSMLPLVRRARGKNCQCLQHSGKSCFL-CRGYCVSKYGVEAFSDILRREIQHFGVKIS 202
Query: 647 AVNPGVITTGL 679
V PG TG+
Sbjct: 203 IVEPGYFRTGM 213
>M62420-1|AAA17881.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>J04056-1|AAA52070.1| 277|Homo sapiens carbonyl reductase protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>EF141836-1|ABK97430.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>CR541708-1|CAG46509.1| 277|Homo sapiens CBR1 protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>BT019843-1|AAV38646.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>BC015640-1|AAH15640.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>BC002511-1|AAH02511.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>AP001724-1|BAA95508.1| 277|Homo sapiens carbonyl reductase
(NAPDH)1, EC 1.1.1.184 protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>AP000688-1|BAA89424.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>AB124848-1|BAE45940.1| 277|Homo sapiens carbonyl reductase 1
protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>AB003151-1|BAA33498.1| 277|Homo sapiens carbonyl reductase
protein.
Length = 277
Score = 54.8 bits (126), Expect = 3e-07
Identities = 41/144 (28%), Positives = 68/144 (47%), Gaps = 1/144 (0%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL-NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
V ++TG + GIG + +L + +VLT R +++ S + + D
Sbjct: 7 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEGLSPRFHQLDIDD 66
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLTM 475
+ + + + ++K Y LDVLVNNAG+ T Q + M TN G +
Sbjct: 67 LQSIRALRDFLRK---EYGGLDVLVNNAGIAFKVADPTPFHIQAEVTMKTNFFGTRDVCT 123
Query: 476 LAIPHLIKTKGNIVNVSSVTGLRS 547
+P LIK +G +VNVSS+ +R+
Sbjct: 124 ELLP-LIKPQGRVVNVSSIMSVRA 146
>AB209653-1|BAD92890.1| 166|Homo sapiens dehydrogenase/reductase
(SDR family) member 2 isoform 2 variant protein.
Length = 166
Score = 53.6 bits (123), Expect = 8e-07
Identities = 27/94 (28%), Positives = 53/94 (56%)
Frame = +2
Query: 104 MFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLV 283
+ AN+V ++TG++SGIG A A+ A +V++ RK++N+D + + + +
Sbjct: 50 VLANRVAVVTGSTSGIGFAIARRLARDGAHVVISSRKQQNVDRAMAKLQGEG---LSVAG 106
Query: 284 VVADMNNESDVENIIKKTVDNYHQLDVLVNNAGV 385
+V + D E ++ K +++ +D LV +AGV
Sbjct: 107 IVCHVGKAEDREQLVAKALEHCGGVDFLVCSAGV 140
>AL023881-4|CAI95592.1| 280|Homo sapiens 2,4-dienoyl CoA reductase
2, peroxisomal protein.
Length = 280
Score = 53.2 bits (122), Expect = 1e-06
Identities = 48/204 (23%), Positives = 87/204 (42%), Gaps = 3/204 (1%)
Frame = +2
Query: 89 LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSK 268
L C ++ +KV ITG SGIG A F + A + +
Sbjct: 20 LFCPDLLRDKVAFITGGGSGIGFRIAEIFMR------------HGCHTAARKLAGATGRR 67
Query: 269 IKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTN 448
PL + D+ V + + + + ++D+L+N A S + +M+ +
Sbjct: 68 CLPLSM--DVRAPPAVMAAVDQALKEFGRIDILINCAAGNFLCPAGALSFNAFKTVMDID 125
Query: 449 VRGPYYLTMLAIPHLIKTKGN-IVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVA 625
G + ++ + + G IVN+++ G R + +K+A+D TR +A+E
Sbjct: 126 TSGTFNVSRVLYEKFFRDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRHLAVEWG 185
Query: 626 LKGVRVNAVNPGVI--TTGLHKKG 691
+ +RVN++ PG I T GL + G
Sbjct: 186 PQNIRVNSLAPGPISGTEGLRRLG 209
>AY092415-1|AAM18189.1| 196|Homo sapiens endoplasmic
reticulum-associated amyloid beta peptide-binding
protein protein.
Length = 196
Score = 52.8 bits (121), Expect = 1e-06
Identities = 39/143 (27%), Positives = 68/143 (47%), Gaps = 13/143 (9%)
Frame = +2
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNV 451
AD+ +E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+
Sbjct: 13 ADVTSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNL 72
Query: 452 RGPYYLTMLAIPHLIKT-------KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCV 610
G + + L + + +G I+N +SV AY SK I T +
Sbjct: 73 MGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPI 132
Query: 611 ALEVALKGVRVNAVNPGVITTGL 679
A ++A G+RV + PG+ T L
Sbjct: 133 ARDLAPIGIRVMTIAPGLFGTPL 155
>AC092630-1|AAY15035.1| 198|Homo sapiens unknown protein.
Length = 198
Score = 52.8 bits (121), Expect = 1e-06
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 13/180 (7%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL---NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
V ++TGAS G G A A L + LVL+ R E L + ++ ++ S ++ + V
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAER-SGLRVVRVP 67
Query: 290 ADMNNESDVENIIKKTVDNYH----QLDVLVNNAGVL---ESGTIETTSLAQYDRIMNTN 448
AD+ E+ ++ ++ + Q +L+NNAG L G ++ + Q + N
Sbjct: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127
Query: 449 VRGPYYLT---MLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ LT + A P +VN+SS+ L+ F YC K+A D + +ALE
Sbjct: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187
>AB017547-1|BAA34534.1| 198|Homo sapiens sepiapterin reductase
protein.
Length = 198
Score = 52.8 bits (121), Expect = 1e-06
Identities = 49/180 (27%), Positives = 83/180 (46%), Gaps = 13/180 (7%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKL---NAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
V ++TGAS G G A A L + LVL+ R E L + ++ ++ S ++ + V
Sbjct: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAER-SGLRVVRVP 67
Query: 290 ADMNNESDVENIIKKTVDNYH----QLDVLVNNAGVL---ESGTIETTSLAQYDRIMNTN 448
AD+ E+ ++ ++ + Q +L+NNAG L G ++ + Q + N
Sbjct: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127
Query: 449 VRGPYYLT---MLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ LT + A P +VN+SS+ L+ F YC K+A D + +ALE
Sbjct: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187
>Z97054-7|CAI42652.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 13/186 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V +ITG +SG+G TA A VL +L N + +++ + AD+
Sbjct: 12 VAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGN-NCVFAPADV 65
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNVRGP 460
+E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+ G
Sbjct: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125
Query: 461 YYLTMLAI-------PHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ + L P +G I+N +SV AY SK I T +A +
Sbjct: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185
Query: 620 VALKGV 637
+A G+
Sbjct: 186 LAPIGL 191
>BC008708-1|AAH08708.1| 252|Homo sapiens hydroxysteroid (17-beta)
dehydrogenase 10 protein.
Length = 252
Score = 52.4 bits (120), Expect = 2e-06
Identities = 48/186 (25%), Positives = 82/186 (44%), Gaps = 13/186 (6%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVADM 298
V +ITG +SG+G TA A VL +L N + +++ + AD+
Sbjct: 12 VAVITGGASGLGLATAERLVGQGASAVLL-----DLPNSGGEAQAKKLGN-NCVFAPADV 65
Query: 299 NNESDVENIIKKTVDNYHQLDVLVNNAGV-LESGTI-----ETTSLAQYDRIMNTNVRGP 460
+E DV+ + + ++DV VN AG+ + S T +T +L + R+++ N+ G
Sbjct: 66 TSEKDVQTALALAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLDVNLMGT 125
Query: 461 YYLTMLAI-------PHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALE 619
+ + L P +G I+N +SV AY SK I T +A +
Sbjct: 126 FNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMTLPIARD 185
Query: 620 VALKGV 637
+A G+
Sbjct: 186 LAPIGL 191
>BC009881-1|AAH09881.1| 260|Homo sapiens retinol dehydrogenase 13
(all-trans/9-cis) protein.
Length = 260
Score = 51.2 bits (117), Expect = 4e-06
Identities = 40/143 (27%), Positives = 66/143 (46%), Gaps = 14/143 (9%)
Frame = +2
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ + + K ++ ++D+L+NNAGV+ T+ ++ N G + LT
Sbjct: 26 DLASLKSIREFAAKIIEEEERVDILINNAGVMRCP--HWTTEDGFEMQFGVNHLGHFLLT 83
Query: 473 MLAIPHL-IKTKGNIVNVSSVTGL-------------RSFPNVLAYCISKSAIDQFTRCV 610
L + L I+N+SS+ + R + AYC SK AI FT+ +
Sbjct: 84 NLLLDKLKASAPSRIINLSSLAHVAGHIDFDDLNWQTRKYNTKAAYCQSKLAIVLFTKEL 143
Query: 611 ALEVALKGVRVNAVNPGVITTGL 679
+ + GV VNA++PGV T L
Sbjct: 144 SRRLQGSGVTVNALHPGVARTEL 166
>U63296-1|AAB53034.1| 143|Homo sapiens 15-hydroxyprostaglandin
dehydrogenase protein.
Length = 143
Score = 50.8 bits (116), Expect = 5e-06
Identities = 31/99 (31%), Positives = 49/99 (49%)
Frame = +2
Query: 116 KVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVAD 295
KV ++TGA+ GIG A AK+ L E + + Q + K L + D
Sbjct: 6 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEAGVQCKAALDEQFEPQ-KTLFIQCD 64
Query: 296 MNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT 412
+ ++ + + +K VD++ +LD+LVNNAGV E T
Sbjct: 65 VADQQQLRDTFRKVVDHFGRLDILVNNAGVNNEKNWEKT 103
>AF240698-1|AAF82748.1| 279|Homo sapiens retinol dehydrogenase
homolog isoform-1 protein.
Length = 279
Score = 50.0 bits (114), Expect = 9e-06
Identities = 47/188 (25%), Positives = 85/188 (45%), Gaps = 4/188 (2%)
Frame = +2
Query: 101 EMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPL 280
E +K + ITG SG G A F K ++ + ++ ++++ +++ +
Sbjct: 25 EDITDKYIFITGCDSGFGNLAARTFDKKGFHVIAACLTESG----STALKAETSERLRTV 80
Query: 281 VV-VADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETT---SLAQYDRIMNTN 448
++ V D N +K V L L+NNAGV G + T +L Y + N
Sbjct: 81 LLDVTDPENVKRTAQWVKNQVGE-KGLWGLINNAGV--PGVLAPTDWLTLEDYREPIEVN 137
Query: 449 VRGPYYLTMLAIPHLIKTKGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVAL 628
+ G +T+ +P + K +G ++NVSSV G + Y SK A++ F + ++
Sbjct: 138 LFGLISVTLNMLPLVKKAQGRVINVSSVGGRLAIVGG-GYTPSKYAVEGFNDSLRRDMKA 196
Query: 629 KGVRVNAV 652
GV V+ +
Sbjct: 197 FGVHVSCI 204
>AF069291-3|AAC62233.1| 188|Homo sapiens 2,4-dienoyl-CoA reductase
protein.
Length = 188
Score = 50.0 bits (114), Expect = 9e-06
Identities = 37/149 (24%), Positives = 67/149 (44%), Gaps = 1/149 (0%)
Frame = +2
Query: 62 SRNFTKLWK-LLCTEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVA 238
S+ F+ L K +L F KV ITG +G+G + L A+ V+ RK + L A
Sbjct: 41 SKFFSPLQKAMLPPNSFQGKVAFITGGGTGLGKGMTTLLSSLGAQCVIASRKMDVLKATA 100
Query: 239 SDCESQSPSKIKPLVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSL 418
SQ+ +K+ + D+ + V+N + + + ++++NNA E S
Sbjct: 101 EQISSQTGNKVH--AIQCDVRDPDMVQNTVSELIKVAGHPNIVINNAAGNFISPTERLSP 158
Query: 419 AQYDRIMNTNVRGPYYLTMLAIPHLIKTK 505
+ I + + G ++T+ LIK +
Sbjct: 159 NAWKTITDIVLNGTAFVTLEIGKQLIKAQ 187
>CR381696-3|CAI95411.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 49.6 bits (113), Expect = 1e-05
Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 5/146 (3%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
++V I+TG + GIG TA A+L +++ G V S + ++ + K +
Sbjct: 120 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYC 178
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ + + + ++K L VL+NNAGV+ +T ++ N G + LT
Sbjct: 179 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRD--GFEEHFGLNYLGHFLLT 236
Query: 473 MLAIPHLIKT-----KGNIVNVSSVT 535
L + L ++ +V VSS T
Sbjct: 237 NLLLDTLKESGSPGHSARVVTVSSAT 262
>BX649443-3|CAI95432.1| 266|Homo sapiens dehydrogenase/reductase
(SDR family) X-linked protein.
Length = 266
Score = 49.6 bits (113), Expect = 1e-05
Identities = 37/146 (25%), Positives = 66/146 (45%), Gaps = 5/146 (3%)
Frame = +2
Query: 113 NKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVVA 292
++V I+TG + GIG TA A+L +++ G V S + ++ + K +
Sbjct: 120 DRVAIVTGGTDGIGYSTAKHLARLGMHVIIAGNNDSKAKQVVSKIKEETLND-KVEFLYC 178
Query: 293 DMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYLT 472
D+ + + + ++K L VL+NNAGV+ +T ++ N G + LT
Sbjct: 179 DLASMTSIRQFVQKFKMKKIPLHVLINNAGVMMVPQRKTRD--GFEEHFGLNYLGHFLLT 236
Query: 473 MLAIPHLIKT-----KGNIVNVSSVT 535
L + L ++ +V VSS T
Sbjct: 237 NLLLDTLKESGSPGHSARVVTVSSAT 262
>M29037-1|AAB17014.1| 214|Homo sapiens 17 beta-hydroxysteroid
dehydrogenase protein.
Length = 214
Score = 49.2 bits (112), Expect = 2e-05
Identities = 48/201 (23%), Positives = 89/201 (44%), Gaps = 4/201 (1%)
Frame = +2
Query: 119 VVIITGASSGIGAETAYEFA---KLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
VV+ITG SSGIG A A + K+ T R + + + + + +
Sbjct: 5 VVLITGCSSGIGLHLAIHLALDPSQSFKVYATLRDLKTQGRLWEAARALACPQGSLERLQ 64
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRGPYYL 469
D+ N S + ++ + ++DVLV N G+ G + ++A +++ NV G +
Sbjct: 65 LDVRNSSSLAAARERVTEG--RVDVLVCNTGLGLLGPLGEDAVAS---VLDVNVVGTVRV 119
Query: 470 TMLAIPHLIKT-KGNIVNVSSVTGLRSFPNVLAYCISKSAIDQFTRCVALEVALKGVRVN 646
+P + + G ++ S+ GL P YC SK A++ +A+ + GV V+
Sbjct: 120 LQDFLPDMKRPGSGRVLVTGSMGGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHVS 179
Query: 647 AVNPGVITTGLHKKGEGSMNE 709
+ G + T +K G ++
Sbjct: 180 LIECGPVDTAFMQKVLGGPDQ 200
>BC051291-1|AAH51291.1| 305|Homo sapiens RDH11 protein protein.
Length = 305
Score = 49.2 bits (112), Expect = 2e-05
Identities = 57/207 (27%), Positives = 95/207 (45%), Gaps = 13/207 (6%)
Frame = +2
Query: 98 TEMFANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKP 277
T KVV++TGA++G A++ L R E + VA + ++ + ++ +
Sbjct: 36 TVQLPGKVVVVTGANTG-------------ARVYLACRDVEKGELVAKEIQTTTGNQ-QV 81
Query: 278 LVVVADMNNESDVENIIKKTVDNYHQLDVLVNNAGVLESGTIETTSLAQYDRIMNTNVRG 457
LV D+++ + K + L VL+NNAGV+ +T ++ + N G
Sbjct: 82 LVRKLDLSDTKSIRAFAKGFLAEEKHLHVLINNAGVMMCPYSKTAD--GFEMHIGVNHLG 139
Query: 458 PYYLTMLAIPHLIKT-KGNIVNVSSVT---GLRSFPNV---------LAYCISKSAIDQF 598
+ LT L + L ++ IVNV S+ G F N+ LAYC SK A F
Sbjct: 140 HFLLTHLLLEKLKESAPSRIVNVFSLAHHLGRIHFHNLQGEKFYNAGLAYCHSKLANILF 199
Query: 599 TRCVALEVALKGVRVNAVNPGVITTGL 679
T+ +A + GV +V+PG + + L
Sbjct: 200 TQELARRLKGSGVTTYSVHPGTVQSEL 226
>AY616182-1|AAT70757.1| 188|Homo sapiens NADP(H)-dependent retinol
dehydrogenase A2 isoform protein.
Length = 188
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/92 (28%), Positives = 48/92 (52%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
ANKV ++T ++ GIG A A+ A +V++ RK++N+D + + + + V
Sbjct: 31 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 87
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGV 385
+ D E ++ V + +D+LV+NA V
Sbjct: 88 CHVGKAEDRERLVATAVKLHGGIDILVSNAAV 119
>AY071856-1|AAL61824.2| 174|Homo sapiens NADP-dependent retinol
dehydrogenase short isoform protein.
Length = 174
Score = 49.2 bits (112), Expect = 2e-05
Identities = 26/92 (28%), Positives = 48/92 (52%)
Frame = +2
Query: 110 ANKVVIITGASSGIGAETAYEFAKLNAKLVLTGRKKENLDNVASDCESQSPSKIKPLVVV 289
ANKV ++T ++ GIG A A+ A +V++ RK++N+D + + + + V
Sbjct: 13 ANKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEG---LSVTGTV 69
Query: 290 ADMNNESDVENIIKKTVDNYHQLDVLVNNAGV 385
+ D E ++ V + +D+LV+NA V
Sbjct: 70 CHVGKAEDRERLVATAVKLHGGIDILVSNAAV 101
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 109,071,494
Number of Sequences: 237096
Number of extensions: 2246766
Number of successful extensions: 4426
Number of sequences better than 10.0: 326
Number of HSP's better than 10.0 without gapping: 4045
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4157
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9423020542
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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