Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV17f16f
(778 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3 (im... 204 2e-52
BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3 (im... 204 2e-52
AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3 (im... 204 2e-52
AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3 (im... 204 2e-52
AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3 var... 204 2e-52
AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subuni... 204 2e-52
D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein. 204 3e-52
BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3 (im... 204 3e-52
Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein. 203 5e-52
AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog ... 202 1e-51
U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein. 196 1e-49
BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4 (im... 196 1e-49
BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4 (im... 196 1e-49
AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein. 196 1e-49
U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein. 160 6e-39
U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein. 160 6e-39
BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RA... 160 6e-39
AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2 pro... 160 6e-39
BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RA... 159 8e-39
BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RA... 159 8e-39
BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RA... 156 7e-38
CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein. 138 3e-32
BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1 (im... 138 3e-32
BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1 (im... 138 3e-32
BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1 (im... 138 3e-32
BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1 (im... 138 3e-32
S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor ... 134 3e-31
BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5 (im... 130 4e-30
AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5 (im... 130 4e-30
AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein. 129 1e-29
BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6 (im... 127 4e-29
BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6 (im... 127 4e-29
AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6 (im... 127 4e-29
AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6 (im... 127 4e-29
AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subuni... 127 4e-29
AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5 (im... 77 9e-14
AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6 (im... 51 4e-06
CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein. 39 0.017
BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antige... 39 0.017
AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antige... 39 0.017
AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antige... 39 0.017
AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antig... 39 0.017
AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antig... 39 0.017
AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein... 39 0.017
AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antige... 36 0.16
AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antig... 36 0.16
AL513128-2|CAH72208.1| 191|Homo sapiens sperm associated antige... 33 0.87
AL158211-13|CAI15961.1| 191|Homo sapiens sperm associated antig... 33 0.87
Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein. 32 2.0
D50550-1|BAA19516.1| 1032|Homo sapiens LLGL protein. 32 2.0
BC132827-1|AAI32828.1| 949|Homo sapiens CCDC66 protein protein. 31 3.5
BC047509-1|AAH47509.1| 831|Homo sapiens coiled-coil domain cont... 31 3.5
BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat contai... 31 3.5
BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat contai... 31 3.5
AL096748-1|CAB46423.1| 242|Homo sapiens hypothetical protein pr... 31 3.5
AK001882-1|BAA91959.1| 431|Homo sapiens protein ( Homo sapiens ... 31 3.5
BC011728-1|AAH11728.1| 198|Homo sapiens armadillo repeat contai... 31 4.6
AK025813-1|BAB15242.1| 198|Homo sapiens protein ( Homo sapiens ... 31 4.6
BC117686-1|AAI17687.1| 1683|Homo sapiens SHPRH protein protein. 30 8.1
BC117685-1|AAI17686.1| 155|Homo sapiens SHPRH protein protein. 30 8.1
BC113089-1|AAI13090.1| 155|Homo sapiens SHPRH protein protein. 30 8.1
AY163808-1|AAO06907.1| 1659|Homo sapiens helicase-like protein p... 30 8.1
AY161136-1|AAO26201.1| 1683|Homo sapiens SNF2 histone linker PHD... 30 8.1
AL451145-1|CAH70765.1| 1683|Homo sapiens SNF2 histone linker PHD... 30 8.1
AL356599-2|CAI41120.1| 1683|Homo sapiens SNF2 histone linker PHD... 30 8.1
AK075318-1|BAC11544.1| 584|Homo sapiens protein ( Homo sapiens ... 30 8.1
>BC024202-1|AAH24202.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 204 bits (499), Expect = 2e-52
Identities = 98/162 (60%), Positives = 125/162 (77%), Gaps = 1/162 (0%)
Frame = +2
Query: 224 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 403
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 404 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 580
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 581 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
>BC017355-1|AAH17355.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 204 bits (499), Expect = 2e-52
Identities = 98/162 (60%), Positives = 125/162 (77%), Gaps = 1/162 (0%)
Frame = +2
Query: 224 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 403
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 404 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 580
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 581 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
>AL136301-1|CAH71145.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 204 bits (499), Expect = 2e-52
Identities = 98/162 (60%), Positives = 125/162 (77%), Gaps = 1/162 (0%)
Frame = +2
Query: 224 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 403
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 404 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 580
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 581 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
>AL135901-3|CAI40716.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 204 bits (499), Expect = 2e-52
Identities = 98/162 (60%), Positives = 125/162 (77%), Gaps = 1/162 (0%)
Frame = +2
Query: 224 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 403
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 404 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 580
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 581 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
>AK223480-1|BAD97200.1| 521|Homo sapiens karyopherin alpha 3
variant protein.
Length = 521
Score = 204 bits (499), Expect = 2e-52
Identities = 98/162 (60%), Positives = 125/162 (77%), Gaps = 1/162 (0%)
Frame = +2
Query: 224 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 403
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEKSLEDSDVDADFKAQ 69
Query: 404 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 580
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 581 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
>AF005263-1|AAQ13404.1| 521|Homo sapiens importin alpha-3 subunit
protein.
Length = 521
Score = 204 bits (499), Expect = 2e-52
Identities = 98/162 (60%), Positives = 125/162 (77%), Gaps = 1/162 (0%)
Frame = +2
Query: 224 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 403
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 404 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 580
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 581 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
>D89618-1|BAA20378.1| 521|Homo sapiens karyopherin alhph 3 protein.
Length = 521
Score = 204 bits (498), Expect = 3e-52
Identities = 98/162 (60%), Positives = 125/162 (77%), Gaps = 1/162 (0%)
Frame = +2
Query: 224 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 403
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 404 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 580
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDQNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 581 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
>BC035090-1|AAH35090.1| 521|Homo sapiens karyopherin alpha 3
(importin alpha 4) protein.
Length = 521
Score = 204 bits (498), Expect = 3e-52
Identities = 97/162 (59%), Positives = 125/162 (77%), Gaps = 1/162 (0%)
Frame = +2
Query: 224 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 403
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 404 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 580
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 581 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
+LQFE AWALTNIASGTSAQT +V + AVP+FL+LL SPH+
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQDIVQSNAVPLFLRLLRSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
>Y12394-1|CAA73026.1| 521|Homo sapiens SRP1-like protein protein.
Length = 521
Score = 203 bits (496), Expect = 5e-52
Identities = 97/162 (59%), Positives = 125/162 (77%), Gaps = 1/162 (0%)
Frame = +2
Query: 224 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 403
+R+ FKN G+DV+ MRR RNEVT+ELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTMELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 404 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 580
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 581 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
+LQFE AWALTNIASGTSAQT VV + AVP+FL+LL SPH+
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVVQSNAVPLFLRLLRSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
>AF034756-1|AAB87693.1| 521|Homo sapiens importin-alpha homolog
protein.
Length = 521
Score = 202 bits (492), Expect = 1e-51
Identities = 97/162 (59%), Positives = 124/162 (76%), Gaps = 1/162 (0%)
Frame = +2
Query: 224 NRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATT 403
+R+ FKN G+DV+ MRR RNEVTVELRKNKR+E L K+RNVP S ++ ++D +
Sbjct: 10 HRIKSFKNKGRDVETMRRHRNEVTVELRKNKRDEHLLKKRNVPQEESLEDSDVDADFKAQ 69
Query: 404 DLD-ELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNP 580
++ E ++ A ++NP QL+AVQ RKLLS D+NPPID+LI +GILPILV+CL R DNP
Sbjct: 70 NVTLEAILQNATSDNPVVQLSAVQAARKLLSSDRNPPIDDLIKSGILPILVKCLERDDNP 129
Query: 581 ALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
+LQFE AWALTNIASGTSAQT V + AVP+FL+LL SPH+
Sbjct: 130 SLQFEAAWALTNIASGTSAQTQAVGQSNAVPLFLRLLRSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
>U93240-1|AAC25605.1| 521|Homo sapiens importin alpha 3 protein.
Length = 521
Score = 196 bits (477), Expect = 1e-49
Identities = 101/175 (57%), Positives = 128/175 (73%), Gaps = 2/175 (1%)
Frame = +2
Query: 188 ASTDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYST 367
A +K+ + KN FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP
Sbjct: 2 ADNEKLDNQRLKN----FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDIC 57
Query: 368 DEEEIDKN--LATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGIL 541
++ +ID + + T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GIL
Sbjct: 58 EDSDIDGDYRVQNTSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGIL 116
Query: 542 PILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
PILV CL R DNP+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+
Sbjct: 117 PILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +2
Query: 593 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 691
E W L+NI +G Q V+ A VP+ + LL
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL 377
>BC034493-1|AAH34493.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 196 bits (477), Expect = 1e-49
Identities = 101/175 (57%), Positives = 128/175 (73%), Gaps = 2/175 (1%)
Frame = +2
Query: 188 ASTDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYST 367
A +K+ + KN FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP
Sbjct: 2 ADNEKLDNQRLKN----FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDIC 57
Query: 368 DEEEIDKN--LATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGIL 541
++ +ID + + T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GIL
Sbjct: 58 EDSDIDGDYRVQNTSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGIL 116
Query: 542 PILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
PILV CL R DNP+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+
Sbjct: 117 PILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +2
Query: 593 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 691
E W L+NI +G Q V+ A VP+ + LL
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL 377
>BC028691-1|AAH28691.1| 521|Homo sapiens karyopherin alpha 4
(importin alpha 3) protein.
Length = 521
Score = 196 bits (477), Expect = 1e-49
Identities = 101/175 (57%), Positives = 128/175 (73%), Gaps = 2/175 (1%)
Frame = +2
Query: 188 ASTDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYST 367
A +K+ + KN FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP
Sbjct: 2 ADNEKLDNQRLKN----FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDIC 57
Query: 368 DEEEIDKN--LATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGIL 541
++ +ID + + T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GIL
Sbjct: 58 EDSDIDGDYRVQNTSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGIL 116
Query: 542 PILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
PILV CL R DNP+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+
Sbjct: 117 PILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +2
Query: 593 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 691
E W L+NI +G Q V+ A VP+ + LL
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL 377
>AB002533-1|BAA19546.1| 521|Homo sapiens Qip1 protein.
Length = 521
Score = 196 bits (477), Expect = 1e-49
Identities = 101/175 (57%), Positives = 128/175 (73%), Gaps = 2/175 (1%)
Frame = +2
Query: 188 ASTDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYST 367
A +K+ + KN FKN G+D++ MRR+RNEV VELRKNKR+E L KRRNVP
Sbjct: 2 ADNEKLDNQRLKN----FKNKGRDLETMRRQRNEVVVELRKNKRDEHLLKRRNVPHEDIC 57
Query: 368 DEEEIDKN--LATTDLDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGIL 541
++ +ID + + T L+ +V NA++ +N QL+AVQ RKLLS D+NPPID+LI +GIL
Sbjct: 58 EDSDIDGDYRVQNTSLEAIVQNASS-DNQGIQLSAVQAARKLLSSDRNPPIDDLIKSGIL 116
Query: 542 PILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
PILV CL R DNP+LQFE AWALTNIASGTS QT VV + AVP+FL+LL SPH+
Sbjct: 117 PILVHCLERDDNPSLQFEAAWALTNIASGTSEQTQAVVQSNAVPLFLRLLHSPHQ 171
Score = 49.6 bits (113), Expect = 1e-05
Identities = 20/24 (83%), Positives = 22/24 (91%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
NVC+QAVWALGNIIGDGP RD+V
Sbjct: 172 NVCEQAVWALGNIIGDGPQCRDYV 195
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +2
Query: 593 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 691
E W L+NI +G Q V+ A VP+ + LL
Sbjct: 345 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL 377
>U28386-1|AAA69957.1| 529|Homo sapiens hSRP1alpha protein.
Length = 529
Score = 160 bits (388), Expect = 6e-39
Identities = 90/176 (51%), Positives = 113/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 191 STDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISY 361
ST++ A A R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDA 60
Query: 362 STDEEEIDKNLATTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAG 535
++ +E N T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG
Sbjct: 61 TSPLQENRNNQGTVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAG 119
Query: 536 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPH 703
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPH 175
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 45/87 (51%)
Frame = +2
Query: 440 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 619
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 620 ASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+GT QT V+ AGA+ VF LL +P
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNP 347
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 488 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 664
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 665 AVPVFLQLL 691
+ + LL
Sbjct: 421 IIEPLMNLL 429
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
++ +QAVWALGNI GDG V RD V
Sbjct: 177 HISEQAVWALGNIAGDGSVFRDLV 200
Score = 31.1 bits (67), Expect = 4.6
Identities = 18/60 (30%), Positives = 29/60 (48%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G +P + L+ + + + + WAL NIA S + V+ GAV L LL P
Sbjct: 158 VVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVP 216
>U09559-1|AAA65700.1| 529|Homo sapiens Rch1 protein.
Length = 529
Score = 160 bits (388), Expect = 6e-39
Identities = 90/176 (51%), Positives = 113/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 191 STDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISY 361
ST++ A A R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDA 60
Query: 362 STDEEEIDKNLATTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAG 535
++ +E N T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG
Sbjct: 61 TSPLQENRNNQGTVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAG 119
Query: 536 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPH 703
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPH 175
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 45/87 (51%)
Frame = +2
Query: 440 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 619
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 620 ASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+GT QT V+ AGA+ VF LL +P
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNP 347
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 488 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 664
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 665 AVPVFLQLL 691
+ + LL
Sbjct: 421 IIEPLMNLL 429
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
++ +QAVWALGNI GDG V RD V
Sbjct: 177 HISEQAVWALGNIAGDGSVFRDLV 200
Score = 31.1 bits (67), Expect = 4.6
Identities = 18/60 (30%), Positives = 29/60 (48%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G +P + L+ + + + + WAL NIA S + V+ GAV L LL P
Sbjct: 158 VVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVP 216
>BC053343-1|AAH53343.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 160 bits (388), Expect = 6e-39
Identities = 90/176 (51%), Positives = 113/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 191 STDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISY 361
ST++ A A R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDA 60
Query: 362 STDEEEIDKNLATTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAG 535
++ +E N T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG
Sbjct: 61 TSPLQENRNNQGTVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAG 119
Query: 536 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPH 703
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPH 175
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 45/87 (51%)
Frame = +2
Query: 440 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 619
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 620 ASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+GT QT V+ AGA+ VF LL +P
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNP 347
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 488 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 664
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 665 AVPVFLQLL 691
+ + LL
Sbjct: 421 IIEPLMNLL 429
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
++ +QAVWALGNI GDG V RD V
Sbjct: 177 HISEQAVWALGNIAGDGSVFRDLV 200
Score = 31.1 bits (67), Expect = 4.6
Identities = 18/60 (30%), Positives = 29/60 (48%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G +P + L+ + + + + WAL NIA S + V+ GAV L LL P
Sbjct: 158 VVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVP 216
>AJ303086-1|CAC83080.1| 529|Homo sapiens karyopherin alpha 2
protein.
Length = 529
Score = 160 bits (388), Expect = 6e-39
Identities = 90/176 (51%), Positives = 113/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 191 STDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISY 361
ST++ A A R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDA 60
Query: 362 STDEEEIDKNLATTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAG 535
++ +E N T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG
Sbjct: 61 TSPLQENRNNQGTVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAG 119
Query: 536 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPH 703
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASPH 175
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 45/87 (51%)
Frame = +2
Query: 440 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 619
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 620 ASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+GT QT V+ AGA+ VF LL +P
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNP 347
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 488 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 664
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 665 AVPVFLQLL 691
+ + LL
Sbjct: 421 IIEPLMNLL 429
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
++ +QAVWALGNI GDG V RD V
Sbjct: 177 HISEQAVWALGNIAGDGSVFRDLV 200
Score = 31.1 bits (67), Expect = 4.6
Identities = 18/60 (30%), Positives = 29/60 (48%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G +P + L+ + + + + WAL NIA S + V+ GAV L LL P
Sbjct: 158 VVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVP 216
>BT006665-1|AAP35311.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 159 bits (387), Expect = 8e-39
Identities = 90/176 (51%), Positives = 113/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 191 STDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISY 361
ST++ A A R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDA 60
Query: 362 STDEEEIDKNLATTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAG 535
++ +E N T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG
Sbjct: 61 TSPLQENRNNQGTVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAG 119
Query: 536 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPH 703
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPH 175
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 45/87 (51%)
Frame = +2
Query: 440 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 619
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 620 ASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+GT QT V+ AGA+ VF LL +P
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNP 347
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 488 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 664
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 665 AVPVFLQLL 691
+ + LL
Sbjct: 421 IIEPLMNLL 429
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
++ +QAVWALGNI GDG V RD V
Sbjct: 177 HISEQAVWALGNIAGDGSVFRDLV 200
Score = 31.1 bits (67), Expect = 4.6
Identities = 18/60 (30%), Positives = 29/60 (48%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G +P + L+ + + + + WAL NIA S + V+ GAV L LL P
Sbjct: 158 VVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVP 216
>BC005978-1|AAH05978.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 159 bits (387), Expect = 8e-39
Identities = 90/176 (51%), Positives = 113/176 (64%), Gaps = 5/176 (2%)
Frame = +2
Query: 191 STDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISY 361
ST++ A A R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDA 60
Query: 362 STDEEEIDKNLATTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAG 535
++ +E N T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG
Sbjct: 61 TSPLQENRNNQGTVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAG 119
Query: 536 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPH 703
++P V L R D +QFE+AWALTNIASGTS QT VV GA+P F+ LL SPH
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKVVVDGGAIPAFISLLASPH 175
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 45/87 (51%)
Frame = +2
Query: 440 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 619
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 620 ASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+GT QT V+ AGA+ VF LL +P
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNP 347
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 488 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 664
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 665 AVPVFLQLL 691
+ + LL
Sbjct: 421 IIEPLMNLL 429
Score = 39.5 bits (88), Expect = 0.013
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
++ +QAVWALGNI GDG V RD V
Sbjct: 177 HISEQAVWALGNIAGDGSVFRDLV 200
Score = 31.1 bits (67), Expect = 4.6
Identities = 18/60 (30%), Positives = 29/60 (48%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G +P + L+ + + + + WAL NIA S + V+ GAV L LL P
Sbjct: 158 VVDGGAIPAFISLLA-SPHAHISEQAVWALGNIAGDGSVFRDLVIKYGAVDPLLALLAVP 216
>BC067848-1|AAH67848.1| 529|Homo sapiens karyopherin alpha 2 (RAG
cohort 1, importin alpha 1) protein.
Length = 529
Score = 156 bits (379), Expect = 7e-38
Identities = 89/176 (50%), Positives = 112/176 (63%), Gaps = 5/176 (2%)
Frame = +2
Query: 191 STDKMATDQAKNRMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNV---PISY 361
ST++ A A R+H FKN GKD EMRRRR EV VELRK K+++ + KRRNV P
Sbjct: 2 STNENANTPAA-RLHRFKNKGKDSTEMRRRRIEVNVELRKAKKDDQMLKRRNVSSFPDDA 60
Query: 362 STDEEEIDKNLATTD--LDELVMNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAG 535
++ +E N T + +D++V N+ N E QL A Q RKLLS +K PPID +I AG
Sbjct: 61 TSPLQENRNNQGTVNWSVDDIV-KGINSSNVENQLQATQAARKLLSREKQPPIDNIIRAG 119
Query: 536 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPH 703
++P V L R D +QFE+AWALTNIASGTS QT VV GA+ F+ LL SPH
Sbjct: 120 LIPKFVSFLGRTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIRAFISLLASPH 175
Score = 43.6 bits (98), Expect = 8e-04
Identities = 29/87 (33%), Positives = 45/87 (51%)
Frame = +2
Query: 440 ENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNI 619
++PE LA L+ N I ++ G++P LV+ L ++ P + A+ NI
Sbjct: 263 DDPEV-LADTCWAISYLTDGPNERIGMVVKTGVVPQLVKLLGASELPIVT-PALRAIGNI 320
Query: 620 ASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+GT QT V+ AGA+ VF LL +P
Sbjct: 321 VTGTDEQTQVVIDAGALAVFPSLLTNP 347
Score = 43.2 bits (97), Expect = 0.001
Identities = 24/69 (34%), Positives = 37/69 (53%), Gaps = 1/69 (1%)
Frame = +2
Query: 488 LSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAG 664
++ + I +++ G++P LV LS+AD Q E WA+TN S GT Q +VH G
Sbjct: 362 ITAGRQDQIQQVVNHGLVPFLVSVLSKADFKT-QKEAVWAVTNYTSGGTVEQIVYLVHCG 420
Query: 665 AVPVFLQLL 691
+ + LL
Sbjct: 421 IIEPLMNLL 429
Score = 37.1 bits (82), Expect = 0.070
Identities = 15/24 (62%), Positives = 18/24 (75%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
++ +Q VWALGNI GDG V RD V
Sbjct: 177 HISEQDVWALGNIAGDGSVFRDLV 200
>CR456743-1|CAG33024.1| 538|Homo sapiens KPNA1 protein.
Length = 538
Score = 138 bits (333), Expect = 3e-32
Identities = 82/183 (44%), Positives = 110/183 (60%), Gaps = 15/183 (8%)
Frame = +2
Query: 203 MATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEE 379
M T +N R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE
Sbjct: 1 MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEE 60
Query: 380 I--DKNLATTDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDE 520
+ D ++ + M +++PE QL+A Q+ RKLLS + NPPIDE
Sbjct: 61 VMSDGGFHEAQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDE 120
Query: 521 LIAA-GILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMS 697
+I+ G++ V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S
Sbjct: 121 VISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSS 180
Query: 698 PHE 706
E
Sbjct: 181 EFE 183
Score = 36.3 bits (80), Expect = 0.12
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD + RD+V
Sbjct: 184 DVQEQAVWALGNIAGDSTMCRDYV 207
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 688
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 689 L 691
L
Sbjct: 432 L 432
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/67 (29%), Positives = 35/67 (52%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+I AG +PI ++ LS ++ +Q + WAL NIA ++ + V+ +P LQL
Sbjct: 165 VIQAGAVPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 701 HETYVIR 721
+ + R
Sbjct: 224 NRLTMTR 230
Score = 30.3 bits (65), Expect = 8.1
Identities = 20/73 (27%), Positives = 35/73 (47%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 302 VELLM--HNDYKV 312
>BT006959-1|AAP35605.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 138 bits (333), Expect = 3e-32
Identities = 82/183 (44%), Positives = 110/183 (60%), Gaps = 15/183 (8%)
Frame = +2
Query: 203 MATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEE 379
M T +N R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE
Sbjct: 1 MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEE 60
Query: 380 I--DKNLATTDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDE 520
+ D ++ + M +++PE QL+A Q+ RKLLS + NPPIDE
Sbjct: 61 VMSDGGFHEAQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDE 120
Query: 521 LIAA-GILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMS 697
+I+ G++ V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S
Sbjct: 121 VISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSS 180
Query: 698 PHE 706
E
Sbjct: 181 EFE 183
Score = 36.3 bits (80), Expect = 0.12
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD + RD+V
Sbjct: 184 DVQEQAVWALGNIAGDSTMCRDYV 207
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 688
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 689 L 691
L
Sbjct: 432 L 432
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/67 (29%), Positives = 35/67 (52%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+I AG +PI ++ LS ++ +Q + WAL NIA ++ + V+ +P LQL
Sbjct: 165 VIQAGAVPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 701 HETYVIR 721
+ + R
Sbjct: 224 NRLTMTR 230
Score = 30.3 bits (65), Expect = 8.1
Identities = 20/73 (27%), Positives = 35/73 (47%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 302 VELLM--HNDYKV 312
>BC090864-1|AAH90864.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 138 bits (333), Expect = 3e-32
Identities = 82/183 (44%), Positives = 110/183 (60%), Gaps = 15/183 (8%)
Frame = +2
Query: 203 MATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEE 379
M T +N R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE
Sbjct: 1 MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEE 60
Query: 380 I--DKNLATTDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDE 520
+ D ++ + M +++PE QL+A Q+ RKLLS + NPPIDE
Sbjct: 61 VMSDGGFHEAQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDE 120
Query: 521 LIAA-GILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMS 697
+I+ G++ V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S
Sbjct: 121 VISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSS 180
Query: 698 PHE 706
E
Sbjct: 181 EFE 183
Score = 36.3 bits (80), Expect = 0.12
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD + RD+V
Sbjct: 184 DVQEQAVWALGNIAGDSTMYRDYV 207
Score = 35.9 bits (79), Expect = 0.16
Identities = 20/67 (29%), Positives = 35/67 (52%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+I AG +PI ++ LS ++ +Q + WAL NIA ++ + V+ +P LQL
Sbjct: 165 VIQAGAVPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMYRDYVLDCNILPPLLQLFSKQ 223
Query: 701 HETYVIR 721
+ + R
Sbjct: 224 NRLTMTR 230
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 688
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 689 L 691
L
Sbjct: 432 L 432
Score = 30.3 bits (65), Expect = 8.1
Identities = 20/73 (27%), Positives = 35/73 (47%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 302 VELLM--HNDYKV 312
>BC003009-1|AAH03009.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 138 bits (333), Expect = 3e-32
Identities = 82/183 (44%), Positives = 110/183 (60%), Gaps = 15/183 (8%)
Frame = +2
Query: 203 MATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEE 379
M T +N R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE
Sbjct: 1 MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEE 60
Query: 380 I--DKNLATTDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDE 520
+ D ++ + M +++PE QL+A Q+ RKLLS + NPPIDE
Sbjct: 61 VMSDGGFHEAQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDE 120
Query: 521 LIAA-GILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMS 697
+I+ G++ V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S
Sbjct: 121 VISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSS 180
Query: 698 PHE 706
E
Sbjct: 181 EFE 183
Score = 36.3 bits (80), Expect = 0.12
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD + RD+V
Sbjct: 184 DVQEQAVWALGNIAGDSTMCRDYV 207
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 688
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 689 L 691
L
Sbjct: 432 L 432
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/67 (29%), Positives = 35/67 (52%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+I AG +PI ++ LS ++ +Q + WAL NIA ++ + V+ +P LQL
Sbjct: 165 VIQAGAVPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 701 HETYVIR 721
+ + R
Sbjct: 224 NRLTMTR 230
Score = 30.3 bits (65), Expect = 8.1
Identities = 20/73 (27%), Positives = 35/73 (47%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 302 VELLM--HNDYKV 312
>BC002374-1|AAH02374.1| 538|Homo sapiens karyopherin alpha 1
(importin alpha 5) protein.
Length = 538
Score = 138 bits (333), Expect = 3e-32
Identities = 82/183 (44%), Positives = 110/183 (60%), Gaps = 15/183 (8%)
Frame = +2
Query: 203 MATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEE 379
M T +N R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE
Sbjct: 1 MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEE 60
Query: 380 I--DKNLATTDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDE 520
+ D ++ + M +++PE QL+A Q+ RKLLS + NPPIDE
Sbjct: 61 VMSDGGFHEAQINNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDE 120
Query: 521 LIAA-GILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMS 697
+I+ G++ V+ L R +N LQFE+AW LTNIASG S QT V+ AGAVP+F++LL S
Sbjct: 121 VISTPGVVARFVEFLKRKENCTLQFESAWVLTNIASGNSLQTRIVIQAGAVPIFIELLSS 180
Query: 698 PHE 706
E
Sbjct: 181 EFE 183
Score = 36.3 bits (80), Expect = 0.12
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD + RD+V
Sbjct: 184 DVQEQAVWALGNIAGDSTMCRDYV 207
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 688
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 689 L 691
L
Sbjct: 432 L 432
Score = 35.1 bits (77), Expect = 0.28
Identities = 20/67 (29%), Positives = 35/67 (52%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+I AG +PI ++ LS ++ +Q + WAL NIA ++ + V+ +P LQL
Sbjct: 165 VIQAGAVPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 701 HETYVIR 721
+ + R
Sbjct: 224 NRLTMTR 230
Score = 30.3 bits (65), Expect = 8.1
Identities = 20/73 (27%), Positives = 35/73 (47%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 302 VELLM--HNDYKV 312
>S75295-1|AAC60648.1| 538|Homo sapiens nucleoprotein interactor 1
protein.
Length = 538
Score = 134 bits (325), Expect = 3e-31
Identities = 81/183 (44%), Positives = 109/183 (59%), Gaps = 15/183 (8%)
Frame = +2
Query: 203 MATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEE 379
M T +N R+ +KN + DEMRRRR E ++LRK KREE L KRRNV + EEE
Sbjct: 1 MTTPGKENFRLKSYKNKSLNPDEMRRRREEEGLQLRKQKREEQLFKRRNVATAEEETEEE 60
Query: 380 I--DKNLATTDLDELVMNAAN-----------AENPEAQLAAVQQCRKLLSCDKNPPIDE 520
+ D + + M +++PE QL+A Q+ RKLLS + NPPIDE
Sbjct: 61 VMSDGGFHEAQISNMEMAPGGVITSDMIEMIFSKSPEQQLSATQKFRKLLSKEPNPPIDE 120
Query: 521 LIAA-GILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMS 697
+I+ G++ V+ L R +N +LQFE+AW LTNIASG S QT V+ A AVP+F++LL S
Sbjct: 121 VISTPGVVARFVEFLKRKENCSLQFESAWVLTNIASGNSLQTRIVIQARAVPIFIELLSS 180
Query: 698 PHE 706
E
Sbjct: 181 EFE 183
Score = 36.3 bits (80), Expect = 0.12
Identities = 15/24 (62%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD + RD+V
Sbjct: 184 DVQEQAVWALGNIAGDSTMCRDYV 207
Score = 35.9 bits (79), Expect = 0.16
Identities = 23/61 (37%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNK-VVHAGAVPVFLQL 688
I +I A I P L+ L A+ + E AWA+TN SG SA+ K +V G + L
Sbjct: 373 IQTVIDANIFPALISILQTAEFRTRK-EAAWAITNATSGGSAEQIKYLVELGCIKPLCDL 431
Query: 689 L 691
L
Sbjct: 432 L 432
Score = 31.9 bits (69), Expect = 2.6
Identities = 19/67 (28%), Positives = 34/67 (50%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+I A +PI ++ LS ++ +Q + WAL NIA ++ + V+ +P LQL
Sbjct: 165 VIQARAVPIFIELLS-SEFEDVQEQAVWALGNIAGDSTMCRDYVLDCNILPPLLQLFSKQ 223
Query: 701 HETYVIR 721
+ + R
Sbjct: 224 NRLTMTR 230
Score = 30.3 bits (65), Expect = 8.1
Identities = 20/73 (27%), Positives = 35/73 (47%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
K+PP + + L +L L +D L + WAL+ ++ G + + V+ AG
Sbjct: 243 KSPPPEFAKVSPCLNVLSWLLFVSDTDVLA-DACWALSYLSDGPNDKIQAVIDAGVCRRL 301
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 302 VELLM--HNDYKV 312
>BC047409-1|AAH47409.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 130 bits (315), Expect = 4e-30
Identities = 80/184 (43%), Positives = 105/184 (57%), Gaps = 14/184 (7%)
Frame = +2
Query: 197 DKMATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDE 373
D MA+ N RM +KN + EMRRRR E ++LRK KREE L KRRNV + DE
Sbjct: 2 DAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLP-RNDE 60
Query: 374 EEIDKNLATTDLDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPID 517
++ + D+ V + + N + QL A Q+ RKLLS + NPPID
Sbjct: 61 SMLESPIQDPDISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPID 120
Query: 518 ELI-AAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 694
++I G++ V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL
Sbjct: 121 QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLN 180
Query: 695 SPHE 706
S HE
Sbjct: 181 SEHE 184
Score = 37.1 bits (82), Expect = 0.070
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQL 688
I +I A I P+L++ L +A+ + E AWA+TN S GT Q +V G + L
Sbjct: 374 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVALGCIKPLCDL 432
Query: 689 L 691
L
Sbjct: 433 L 433
Score = 36.3 bits (80), Expect = 0.12
Identities = 16/24 (66%), Positives = 18/24 (75%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD RDFV
Sbjct: 185 DVQEQAVWALGNIAGDNAECRDFV 208
Score = 33.1 bits (72), Expect = 1.1
Identities = 18/67 (26%), Positives = 36/67 (53%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+I G +PI ++ L+ +++ +Q + WAL NIA + + V++ +P L+LL +
Sbjct: 166 VIETGAVPIFIKLLN-SEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNS 224
Query: 701 HETYVIR 721
+ R
Sbjct: 225 NRLTTTR 231
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/73 (27%), Positives = 37/73 (50%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
KNPP + + L +L + L +D P + + WAL+ ++ G + + V+ +G
Sbjct: 244 KNPPPNFSKVSPCLNVLSRLLFSSD-PDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRL 302
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 303 VELLM--HNDYKV 313
>AL132795-5|CAI20500.1| 539|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 539
Score = 130 bits (315), Expect = 4e-30
Identities = 80/184 (43%), Positives = 105/184 (57%), Gaps = 14/184 (7%)
Frame = +2
Query: 197 DKMATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDE 373
D MA+ N RM +KN + EMRRRR E ++LRK KREE L KRRNV + DE
Sbjct: 2 DAMASPGKDNYRMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLP-RNDE 60
Query: 374 EEIDKNLATTDLDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPID 517
++ + D+ V + + N + QL A Q+ RKLLS + NPPID
Sbjct: 61 SMLESPIQDPDISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPID 120
Query: 518 ELI-AAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 694
++I G++ V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL
Sbjct: 121 QVIQKPGVVQRFVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLN 180
Query: 695 SPHE 706
S HE
Sbjct: 181 SEHE 184
Score = 37.1 bits (82), Expect = 0.070
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQL 688
I +I A I P+L++ L +A+ + E AWA+TN S GT Q +V G + L
Sbjct: 374 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVALGCIKPLCDL 432
Query: 689 L 691
L
Sbjct: 433 L 433
Score = 36.3 bits (80), Expect = 0.12
Identities = 16/24 (66%), Positives = 18/24 (75%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD RDFV
Sbjct: 185 DVQEQAVWALGNIAGDNAECRDFV 208
Score = 33.1 bits (72), Expect = 1.1
Identities = 18/67 (26%), Positives = 36/67 (53%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+I G +PI ++ L+ +++ +Q + WAL NIA + + V++ +P L+LL +
Sbjct: 166 VIETGAVPIFIKLLN-SEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNS 224
Query: 701 HETYVIR 721
+ R
Sbjct: 225 NRLTTTR 231
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/73 (27%), Positives = 37/73 (50%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
KNPP + + L +L + L +D P + + WAL+ ++ G + + V+ +G
Sbjct: 244 KNPPPNFSKVSPCLNVLSRLLFSSD-PDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRL 302
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 303 VELLM--HNDYKV 313
>AF005361-1|AAC51868.1| 536|Homo sapiens importin alpha 6 protein.
Length = 536
Score = 129 bits (312), Expect = 1e-29
Identities = 76/173 (43%), Positives = 102/173 (58%), Gaps = 13/173 (7%)
Frame = +2
Query: 227 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTD 406
RM +KN + EMRRRR E ++LRK KREE L KRRNV + + DE ++ + +D
Sbjct: 10 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLPRN-DESMLESPIQDSD 68
Query: 407 LDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELIAA-GILPI 547
+ V + + N + QL A Q+ RKLLS + NPPID++I G++
Sbjct: 69 ISSTVPIPEEGVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR 128
Query: 548 LVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
V+ L R +N LQFE AWALTNIASGT T V+ GAVP+F++LL S HE
Sbjct: 129 FVKFLERNENCTLQFEAAWALTNIASGTFLHTKVVIETGAVPIFIKLLNSEHE 181
Score = 37.1 bits (82), Expect = 0.070
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQL 688
I +I A I P+L++ L +A+ + E AWA+TN S GT Q +V G + L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVALGCIKPLCDL 429
Query: 689 L 691
L
Sbjct: 430 L 430
Score = 36.3 bits (80), Expect = 0.12
Identities = 16/24 (66%), Positives = 18/24 (75%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD RDFV
Sbjct: 182 DVQEQAVWALGNIAGDNAECRDFV 205
Score = 33.1 bits (72), Expect = 1.1
Identities = 18/67 (26%), Positives = 36/67 (53%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
+I G +PI ++ L+ +++ +Q + WAL NIA + + V++ +P L+LL +
Sbjct: 163 VIETGAVPIFIKLLN-SEHEDVQEQAVWALGNIAGDNAECRDFVLNCEILPPLLELLTNS 221
Query: 701 HETYVIR 721
+ R
Sbjct: 222 NRLTTTR 228
Score = 32.3 bits (70), Expect = 2.0
Identities = 20/73 (27%), Positives = 37/73 (50%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
KNPP + + L +L + L +D P + + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPNFSKVSPCLNVLSRLLFSSD-PDVLADVCWALSYLSDGPNDKIQAVIDSGVCRRL 299
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 300 VELLM--HNDYKV 310
>BT009843-1|AAP88845.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 127 bits (307), Expect = 4e-29
Identities = 77/180 (42%), Positives = 111/180 (61%), Gaps = 10/180 (5%)
Frame = +2
Query: 197 DKMATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SY 361
+ MA+ N RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + +
Sbjct: 2 ETMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAA 61
Query: 362 STDEEEIDKNLATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI- 526
D +D +++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I
Sbjct: 62 MFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVIN 121
Query: 527 AAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
++ V+ L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E
Sbjct: 122 TPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFE 181
Score = 37.5 bits (83), Expect = 0.053
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD V RD+V
Sbjct: 182 DVQEQAVWALGNIAGDSSVCRDYV 205
Score = 37.5 bits (83), Expect = 0.053
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQL 688
I +I A I P+L++ L +A+ + E AWA+TN S GT Q +V G + L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDL 429
Query: 689 L 691
L
Sbjct: 430 L 430
Score = 37.1 bits (82), Expect = 0.070
Identities = 21/73 (28%), Positives = 38/73 (52%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 300 VELLM--HNDYKV 310
>BC020520-1|AAH20520.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 127 bits (307), Expect = 4e-29
Identities = 77/180 (42%), Positives = 111/180 (61%), Gaps = 10/180 (5%)
Frame = +2
Query: 197 DKMATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SY 361
+ MA+ N RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + +
Sbjct: 2 ETMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAA 61
Query: 362 STDEEEIDKNLATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI- 526
D +D +++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I
Sbjct: 62 MFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVIN 121
Query: 527 AAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
++ V+ L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E
Sbjct: 122 TPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFE 181
Score = 37.5 bits (83), Expect = 0.053
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD V RD+V
Sbjct: 182 DVQEQAVWALGNIAGDSSVCRDYV 205
Score = 37.5 bits (83), Expect = 0.053
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQL 688
I +I A I P+L++ L +A+ + E AWA+TN S GT Q +V G + L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDL 429
Query: 689 L 691
L
Sbjct: 430 L 430
Score = 37.1 bits (82), Expect = 0.070
Identities = 21/73 (28%), Positives = 38/73 (52%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 300 VELLM--HNDYKV 310
>AL445248-5|CAH71948.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 127 bits (307), Expect = 4e-29
Identities = 77/180 (42%), Positives = 111/180 (61%), Gaps = 10/180 (5%)
Frame = +2
Query: 197 DKMATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SY 361
+ MA+ N RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + +
Sbjct: 2 ETMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAA 61
Query: 362 STDEEEIDKNLATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI- 526
D +D +++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I
Sbjct: 62 MFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVIN 121
Query: 527 AAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
++ V+ L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E
Sbjct: 122 TPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFE 181
Score = 37.5 bits (83), Expect = 0.053
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD V RD+V
Sbjct: 182 DVQEQAVWALGNIAGDSSVCRDYV 205
Score = 37.5 bits (83), Expect = 0.053
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQL 688
I +I A I P+L++ L +A+ + E AWA+TN S GT Q +V G + L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDL 429
Query: 689 L 691
L
Sbjct: 430 L 430
Score = 37.1 bits (82), Expect = 0.070
Identities = 21/73 (28%), Positives = 38/73 (52%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 300 VELLM--HNDYKV 310
>AL049795-3|CAI22056.1| 536|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 536
Score = 127 bits (307), Expect = 4e-29
Identities = 77/180 (42%), Positives = 111/180 (61%), Gaps = 10/180 (5%)
Frame = +2
Query: 197 DKMATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SY 361
+ MA+ N RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + +
Sbjct: 2 ETMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAA 61
Query: 362 STDEEEIDKNLATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI- 526
D +D +++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I
Sbjct: 62 MFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVIN 121
Query: 527 AAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
++ V+ L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E
Sbjct: 122 TPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFE 181
Score = 37.5 bits (83), Expect = 0.053
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD V RD+V
Sbjct: 182 DVQEQAVWALGNIAGDSSVCRDYV 205
Score = 37.5 bits (83), Expect = 0.053
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQL 688
I +I A I P+L++ L +A+ + E AWA+TN S GT Q +V G + L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDL 429
Query: 689 L 691
L
Sbjct: 430 L 430
Score = 37.1 bits (82), Expect = 0.070
Identities = 21/73 (28%), Positives = 38/73 (52%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 300 VELLM--HNDYKV 310
>AF060543-1|AAC15233.1| 536|Homo sapiens importin alpha 7 subunit
protein.
Length = 536
Score = 127 bits (307), Expect = 4e-29
Identities = 77/180 (42%), Positives = 111/180 (61%), Gaps = 10/180 (5%)
Frame = +2
Query: 197 DKMATDQAKN-RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPI----SY 361
+ MA+ N RM +KN + +EMRRRR E ++LRK KRE+ L KRRNV + +
Sbjct: 2 ETMASPGKDNYRMKSYKNNALNPEEMRRRREEEGIQLRKQKREQQLFKRRNVELINEEAA 61
Query: 362 STDEEEIDKNLATTDLDELV----MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI- 526
D +D +++T + ++ + +++ + QLA Q+ RKLLS + +PPIDE+I
Sbjct: 62 MFDSLLMDSYVSSTTGESVITREMVEMLFSDDSDLQLATTQKFRKLLSKEPSPPIDEVIN 121
Query: 527 AAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
++ V+ L R +N LQFE AWALTNIASGTS QT V+ AGAVP+F++LL S E
Sbjct: 122 TPRVVDRFVEFLKRNENCTLQFEAAWALTNIASGTSQQTKIVIEAGAVPIFIELLNSDFE 181
Score = 37.5 bits (83), Expect = 0.053
Identities = 16/24 (66%), Positives = 19/24 (79%)
Frame = +1
Query: 706 NVCDQAVWALGNIIGDGPVLRDFV 777
+V +QAVWALGNI GD V RD+V
Sbjct: 182 DVQEQAVWALGNIAGDSSVCRDYV 205
Score = 37.5 bits (83), Expect = 0.053
Identities = 22/61 (36%), Positives = 32/61 (52%), Gaps = 1/61 (1%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIAS-GTSAQTNKVVHAGAVPVFLQL 688
I +I A I P+L++ L +A+ + E AWA+TN S GT Q +V G + L
Sbjct: 371 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSGGTPEQIRYLVSLGCIKPLCDL 429
Query: 689 L 691
L
Sbjct: 430 L 430
Score = 37.1 bits (82), Expect = 0.070
Identities = 21/73 (28%), Positives = 38/73 (52%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 241 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 299
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 300 VELLM--HNDYKV 310
>AL132795-6|CAI20501.1| 142|Homo sapiens karyopherin alpha 5
(importin alpha 6) protein.
Length = 142
Score = 76.6 bits (180), Expect = 9e-14
Identities = 51/134 (38%), Positives = 71/134 (52%), Gaps = 13/134 (9%)
Frame = +2
Query: 227 RMHVFKNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTD 406
RM +KN + EMRRRR E ++LRK KREE L KRRNV + DE ++ + D
Sbjct: 10 RMKSYKNKALNPQEMRRRREEEGIQLRKQKREEQLFKRRNVYLP-RNDESMLESPIQDPD 68
Query: 407 LDELV------------MNAANAENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPI 547
+ V + + N + QL A Q+ RKLLS + NPPID++I G++
Sbjct: 69 ISSTVPIPEEEVVTTDMVQMIFSNNADQQLTATQKFRKLLSKEPNPPIDQVIQKPGVVQR 128
Query: 548 LVQCLSRADNPALQ 589
V+ L R +N LQ
Sbjct: 129 FVKFLERNENCTLQ 142
>AL049795-1|CAI22054.1| 321|Homo sapiens karyopherin alpha 6
(importin alpha 7) protein.
Length = 321
Score = 51.2 bits (117), Expect = 4e-06
Identities = 32/86 (37%), Positives = 49/86 (56%), Gaps = 1/86 (1%)
Frame = +2
Query: 437 AENPEAQLAAVQQCRKLLSCDKNPPIDELI-AAGILPILVQCLSRADNPALQFETAWALT 613
+++ + QLA Q+ RKLLS + +PPIDE+I ++ V+ L R +N LQ WAL
Sbjct: 42 SDDSDLQLATTQKFRKLLSKEPSPPIDEVINTPRVVDRFVEFLKRNENCTLQ--AVWALG 99
Query: 614 NIASGTSAQTNKVVHAGAVPVFLQLL 691
NIA +S + V++ + L LL
Sbjct: 100 NIAGDSSVCRDYVLNCSILNPLLTLL 125
Score = 37.1 bits (82), Expect = 0.070
Identities = 21/73 (28%), Positives = 38/73 (52%)
Frame = +2
Query: 500 KNPPIDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVF 679
KNPP + + LP+L + L +D+ L + WAL+ ++ G + + V+ +G
Sbjct: 148 KNPPPEFAKVSPCLPVLSRLLFSSDSDLLA-DACWALSYLSDGPNEKIQAVIDSGVCRRL 206
Query: 680 LQLLMSPHETYVI 718
++LLM H Y +
Sbjct: 207 VELLM--HNDYKV 217
Score = 35.9 bits (79), Expect = 0.16
Identities = 15/20 (75%), Positives = 16/20 (80%)
Frame = +1
Query: 718 QAVWALGNIIGDGPVLRDFV 777
QAVWALGNI GD V RD+V
Sbjct: 93 QAVWALGNIAGDSSVCRDYV 112
Score = 33.5 bits (73), Expect = 0.87
Identities = 16/39 (41%), Positives = 24/39 (61%)
Frame = +2
Query: 512 IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASG 628
I +I A I P+L++ L +A+ + E AWA+TN SG
Sbjct: 278 IQAVIDANIFPVLIEILQKAEFRTRK-EAAWAITNATSG 315
>CR533552-1|CAG38583.1| 509|Homo sapiens SPAG6 protein.
Length = 509
Score = 39.1 bits (87), Expect = 0.017
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSRAVVDAGAVPLLVLCIQEP 179
Score = 34.7 bits (76), Expect = 0.38
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 362 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 514
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 515 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 694
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 695 S 697
S
Sbjct: 389 S 389
>BC030585-1|AAH30585.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 39.1 bits (87), Expect = 0.017
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Score = 34.7 bits (76), Expect = 0.38
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 362 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 514
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 515 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 694
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 695 S 697
S
Sbjct: 389 S 389
>AL513128-4|CAH72210.1| 509|Homo sapiens sperm associated antigen 6
protein.
Length = 509
Score = 39.1 bits (87), Expect = 0.017
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Score = 34.7 bits (76), Expect = 0.38
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 362 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 514
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 515 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 694
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 695 S 697
S
Sbjct: 389 S 389
>AL513128-3|CAH72209.1| 458|Homo sapiens sperm associated antigen 6
protein.
Length = 458
Score = 39.1 bits (87), Expect = 0.017
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Score = 34.7 bits (76), Expect = 0.38
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 362 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 514
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 515 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 694
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 695 S 697
S
Sbjct: 389 S 389
>AL158211-15|CAI15963.1| 509|Homo sapiens sperm associated antigen
6 protein.
Length = 509
Score = 39.1 bits (87), Expect = 0.017
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Score = 34.7 bits (76), Expect = 0.38
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 362 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 514
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 515 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 694
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 695 S 697
S
Sbjct: 389 S 389
>AL158211-14|CAI15962.1| 458|Homo sapiens sperm associated antigen
6 protein.
Length = 458
Score = 39.1 bits (87), Expect = 0.017
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Score = 34.7 bits (76), Expect = 0.38
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 362 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 514
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 515 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 694
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 695 S 697
S
Sbjct: 389 S 389
>AF079363-1|AAC32590.1| 509|Homo sapiens sperm flagellar protein
Repro-SA-1 protein.
Length = 509
Score = 39.1 bits (87), Expect = 0.017
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSP 700
++ G L LV CL D P ++ AWAL IA + + VV AGAVP+ + + P
Sbjct: 121 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVPLLVLCIQEP 179
Score = 34.7 bits (76), Expect = 0.38
Identities = 33/121 (27%), Positives = 49/121 (40%), Gaps = 9/121 (7%)
Frame = +2
Query: 362 STDEEEIDKNLATTDLDELVMNAANAE---------NPEAQLAAVQQCRKLLSCDKNPPI 514
ST EI K+ T +L +LV+NA +L + + + +N +
Sbjct: 272 STLIREIAKH--TPELSQLVVNAGGVAAVIDCIGSCKGNTRLPGIMMLGYVAAHSENLAM 329
Query: 515 DELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLM 694
+I+ G+ P L CLS ++ AWAL I T V +PV L L M
Sbjct: 330 AVIISKGV-PQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVTNTLPVLLSLYM 388
Query: 695 S 697
S
Sbjct: 389 S 389
>AL513128-1|CAH72207.1| 246|Homo sapiens sperm associated antigen 6
protein.
Length = 246
Score = 35.9 bits (79), Expect = 0.16
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVP 673
++ G L LV CL D P ++ AWAL IA + + VV AGAVP
Sbjct: 197 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVP 246
>AL158211-12|CAI15960.1| 246|Homo sapiens sperm associated antigen
6 protein.
Length = 246
Score = 35.9 bits (79), Expect = 0.16
Identities = 21/51 (41%), Positives = 27/51 (52%)
Frame = +2
Query: 521 LIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVP 673
++ G L LV CL D P ++ AWAL IA + + VV AGAVP
Sbjct: 197 IVDCGALDTLVICLEDFD-PGVKEAAAWALRYIARHNAELSQAVVDAGAVP 246
>AL513128-2|CAH72208.1| 191|Homo sapiens sperm associated antigen 6
protein.
Length = 191
Score = 33.5 bits (73), Expect = 0.87
Identities = 22/72 (30%), Positives = 29/72 (40%), Gaps = 1/72 (1%)
Frame = +2
Query: 485 LLSCDKNPP-IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHA 661
++ CD P + L +P L CLS ++ AWAL I T V
Sbjct: 79 VVKCDILPQLVYSLAEQNGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVT 138
Query: 662 GAVPVFLQLLMS 697
+PV L L MS
Sbjct: 139 NTLPVLLSLYMS 150
>AL158211-13|CAI15961.1| 191|Homo sapiens sperm associated antigen
6 protein.
Length = 191
Score = 33.5 bits (73), Expect = 0.87
Identities = 22/72 (30%), Positives = 29/72 (40%), Gaps = 1/72 (1%)
Frame = +2
Query: 485 LLSCDKNPP-IDELIAAGILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHA 661
++ CD P + L +P L CLS ++ AWAL I T V
Sbjct: 79 VVKCDILPQLVYSLAEQNGVPQLSVCLSEEPEDHIKAAAAWALGQIGRHTPEHARAVAVT 138
Query: 662 GAVPVFLQLLMS 697
+PV L L MS
Sbjct: 139 NTLPVLLSLYMS 150
>Y12393-1|CAA73025.1| 281|Homo sapiens SRP1-like protein protein.
Length = 281
Score = 32.3 bits (70), Expect = 2.0
Identities = 13/33 (39%), Positives = 18/33 (54%)
Frame = +2
Query: 593 ETAWALTNIASGTSAQTNKVVHAGAVPVFLQLL 691
E W L+NI +G Q V+ A VP+ + LL
Sbjct: 105 EAVWFLSNITAGNQQQVQAVIDANLVPMIIHLL 137
>D50550-1|BAA19516.1| 1032|Homo sapiens LLGL protein.
Length = 1032
Score = 32.3 bits (70), Expect = 2.0
Identities = 21/61 (34%), Positives = 31/61 (50%), Gaps = 1/61 (1%)
Frame = +2
Query: 530 AGILP-ILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHE 706
AG LP +LVQCL A A+ T W+L +A GTS + PV + + P++
Sbjct: 585 AGFLPRVLVQCLPPAAVTAVTLHTEWSL--VAFGTSHGFGLFDYQRKSPVLARCTLHPND 642
Query: 707 T 709
+
Sbjct: 643 S 643
>BC132827-1|AAI32828.1| 949|Homo sapiens CCDC66 protein protein.
Length = 949
Score = 31.5 bits (68), Expect = 3.5
Identities = 23/82 (28%), Positives = 37/82 (45%)
Frame = +2
Query: 242 KNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELV 421
K K ++E +R++ E ELR + E +QK+ I +EEI T +EL
Sbjct: 478 KRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEEI----MTLKTNELF 533
Query: 422 MNAANAENPEAQLAAVQQCRKL 487
A+ +L Q+ R+L
Sbjct: 534 QTMQRAQELAQRLKQEQRIREL 555
>BC047509-1|AAH47509.1| 831|Homo sapiens coiled-coil domain
containing 66 protein.
Length = 831
Score = 31.5 bits (68), Expect = 3.5
Identities = 23/82 (28%), Positives = 37/82 (45%)
Frame = +2
Query: 242 KNAGKDVDEMRRRRNEVTVELRKNKREETLQKRRNVPISYSTDEEEIDKNLATTDLDELV 421
K K ++E +R++ E ELR + E +QK+ I +EEI T +EL
Sbjct: 361 KRRKKQLEEEQRKKEEQEEELRLAQEREEMQKQYEEDILKQKQKEEI----MTLKTNELF 416
Query: 422 MNAANAENPEAQLAAVQQCRKL 487
A+ +L Q+ R+L
Sbjct: 417 QTMQRAQELAQRLKQEQRIREL 438
>BC041699-1|AAH41699.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 31.5 bits (68), Expect = 3.5
Identities = 19/63 (30%), Positives = 36/63 (57%)
Frame = +2
Query: 434 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 613
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 423 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 479
Query: 614 NIA 622
N+A
Sbjct: 480 NMA 482
>BC032661-1|AAH32661.1| 659|Homo sapiens armadillo repeat
containing 8 protein.
Length = 659
Score = 31.5 bits (68), Expect = 3.5
Identities = 19/63 (30%), Positives = 36/63 (57%)
Frame = +2
Query: 434 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 613
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 423 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 479
Query: 614 NIA 622
N+A
Sbjct: 480 NMA 482
>AL096748-1|CAB46423.1| 242|Homo sapiens hypothetical protein
protein.
Length = 242
Score = 31.5 bits (68), Expect = 3.5
Identities = 19/63 (30%), Positives = 36/63 (57%)
Frame = +2
Query: 434 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 613
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 6 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 62
Query: 614 NIA 622
N+A
Sbjct: 63 NMA 65
>AK001882-1|BAA91959.1| 431|Homo sapiens protein ( Homo sapiens
cDNA FLJ11020 fis, clone PLACE1003625, weakly similar to
ARMADILLO SEGMENT POLARITY PROTEIN. ).
Length = 431
Score = 31.5 bits (68), Expect = 3.5
Identities = 19/63 (30%), Positives = 36/63 (57%)
Frame = +2
Query: 434 NAENPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAWALT 613
NA + +A+ C LL + +P + ++ +G + +L L++++NPAL+ WAL
Sbjct: 195 NAPDEILVVASSMLCNLLL--EFSPSKEPILESGAVELLCG-LTQSENPALRVNGIWALM 251
Query: 614 NIA 622
N+A
Sbjct: 252 NMA 254
>BC011728-1|AAH11728.1| 198|Homo sapiens armadillo repeat
containing 7 protein.
Length = 198
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/61 (27%), Positives = 30/61 (49%)
Frame = +2
Query: 536 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHETYV 715
+L + + LS + ++F L N+ A ++HAG VP+ + L SP+E V
Sbjct: 58 VLDLFLDSLSEENETLVEFAIG-GLCNLCPDR-ANKEHILHAGGVPLIINCLSSPNEETV 115
Query: 716 I 718
+
Sbjct: 116 L 116
>AK025813-1|BAB15242.1| 198|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22160 fis, clone HRC00266. ).
Length = 198
Score = 31.1 bits (67), Expect = 4.6
Identities = 17/61 (27%), Positives = 30/61 (49%)
Frame = +2
Query: 536 ILPILVQCLSRADNPALQFETAWALTNIASGTSAQTNKVVHAGAVPVFLQLLMSPHETYV 715
+L + + LS + ++F L N+ A ++HAG VP+ + L SP+E V
Sbjct: 58 VLDLFLDSLSEENETLVEFAIG-GLCNLCPDR-ANKEHILHAGGVPLIINCLSSPNEETV 115
Query: 716 I 718
+
Sbjct: 116 L 116
>BC117686-1|AAI17687.1| 1683|Homo sapiens SHPRH protein protein.
Length = 1683
Score = 30.3 bits (65), Expect = 8.1
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 275 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 442
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 443 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 604
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>BC117685-1|AAI17686.1| 155|Homo sapiens SHPRH protein protein.
Length = 155
Score = 30.3 bits (65), Expect = 8.1
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 275 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 442
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 443 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 604
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>BC113089-1|AAI13090.1| 155|Homo sapiens SHPRH protein protein.
Length = 155
Score = 30.3 bits (65), Expect = 8.1
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 275 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 442
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 443 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 604
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AY163808-1|AAO06907.1| 1659|Homo sapiens helicase-like protein
protein.
Length = 1659
Score = 30.3 bits (65), Expect = 8.1
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 275 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 442
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 443 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 604
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AY161136-1|AAO26201.1| 1683|Homo sapiens SNF2 histone linker PHD
RING helicase protein.
Length = 1683
Score = 30.3 bits (65), Expect = 8.1
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 275 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 442
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 443 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 604
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AL451145-1|CAH70765.1| 1683|Homo sapiens SNF2 histone linker PHD
RING helicase protein.
Length = 1683
Score = 30.3 bits (65), Expect = 8.1
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 275 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 442
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 443 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 604
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AL356599-2|CAI41120.1| 1683|Homo sapiens SNF2 histone linker PHD
RING helicase protein.
Length = 1683
Score = 30.3 bits (65), Expect = 8.1
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 275 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 442
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 443 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 604
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
>AK075318-1|BAC11544.1| 584|Homo sapiens protein ( Homo sapiens
cDNA FLJ90837 fis, clone Y79AA1002121, weakly similar to
HISTONE H1. ).
Length = 584
Score = 30.3 bits (65), Expect = 8.1
Identities = 29/114 (25%), Positives = 53/114 (46%), Gaps = 4/114 (3%)
Frame = +2
Query: 275 RRRNEVTVELRKNKREETL----QKRRNVPISYSTDEEEIDKNLATTDLDELVMNAANAE 442
RR+ V + + KR++ + RRN PI S D+E+ T+ ++++ + E
Sbjct: 4 RRKRAPPVRVDEEKRQQLHWNMHEDRRNEPIIISDDDEQPCPGSDTSSAHYIILSDSLKE 63
Query: 443 NPEAQLAAVQQCRKLLSCDKNPPIDELIAAGILPILVQCLSRADNPALQFETAW 604
E ++C K++S K PI++ GI L L+ +P F+ +W
Sbjct: 64 --EVAHRDKKRCSKVVSFSK--PIEKEETVGIFSPLSVKLNIVISP-YHFDNSW 112
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 114,394,220
Number of Sequences: 237096
Number of extensions: 2573396
Number of successful extensions: 6540
Number of sequences better than 10.0: 66
Number of HSP's better than 10.0 without gapping: 5935
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6476
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9423020542
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -