Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV17d21f
(751 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 246 5e-65
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 246 5e-65
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 246 9e-65
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 246 9e-65
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 225 2e-58
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 223 7e-58
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 223 7e-58
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 223 7e-58
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 223 7e-58
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 210 5e-54
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 210 5e-54
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 210 5e-54
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 210 5e-54
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 210 5e-54
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 209 9e-54
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 194 3e-49
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 192 1e-48
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 192 1e-48
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 192 1e-48
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 102 2e-21
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 99 2e-20
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 99 2e-20
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 98 3e-20
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 246 bits (603), Expect = 5e-65
Identities = 105/216 (48%), Positives = 145/216 (67%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
F DDFL+G ++++YQIEGAWD DGKG +IWD TH + + D + GDIA DSYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ M+R L + YRFS+SWSRI P+G + +N GVDYYNRLIN ++ NI PM++L+HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ LQ++GG+ NP + D F+ Y F GDRVK W+TFNEP + + GYGS E P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGG 731
+ Y A ++ AHA+ Y Y+ +++ +Q G
Sbjct: 1083 VKDPGWAPYRIAHTVIKAHARVYHTYDEKYRQEQKG 1118
Score = 245 bits (600), Expect = 1e-64
Identities = 108/223 (48%), Positives = 152/223 (68%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 RFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVER 260
RFP+ F++ A+A+YQIEGAW DGKG +IWD +H P + +++ GD+A DSYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHW 440
D+ ++ LG+ YRFS+SWSRILP G +NEAG++YY RLI+ +L +I P +++YHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
DLPQ LQ++GG+ N I F++Y V+F +LGD+VK WIT NEP V+ YQGYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -MLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ N Y+ NL+ AHA+A+ LYN+ ++ QGG IT
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISIT 1597
Score = 204 bits (498), Expect = 3e-52
Identities = 94/223 (42%), Positives = 137/223 (61%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNV 254
Q FP+ FL+G +T ++ +EG W E G+G +IWD N T ++ ++A+DSYH V
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTT--EGQATLEVASDSYHKV 436
Query: 255 ERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLY 434
DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + I PM +L+
Sbjct: 437 ASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLF 496
Query: 435 HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEK 614
HWDLPQ LQ+ GG+ N + D F DY F+ GDRVKLW+TF+EP V+ Y GYG+ +
Sbjct: 497 HWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQH 556
Query: 615 APMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
P ++ V ++ A +L AHA+ + YN+ + +Q G GI
Sbjct: 557 PPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGI 599
Score = 64.5 bits (150), Expect = 4e-10
Identities = 44/150 (29%), Positives = 68/150 (45%), Gaps = 1/150 (0%)
Frame = +3
Query: 297 YRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWDLP-QKLQELGG 473
Y+ +SW+++LP+G +E V Y RL+ + + PM+ L+H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPMLNATAVGTYM 653
F AD F DY F GD V +W TF++ V + +A L
Sbjct: 147 F-----ADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQL--------- 192
Query: 654 CARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
+ L AH KAY +Y+ + QGG+ +
Sbjct: 193 --QTLSDAHRKAYEIYHESY-AFQGGKLSV 219
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 246 bits (603), Expect = 5e-65
Identities = 105/216 (48%), Positives = 145/216 (67%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
F DDFL+G ++++YQIEGAWD DGKG +IWD TH + + D + GDIA DSYH ++ D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ M+R L + YRFS+SWSRI P+G + +N GVDYYNRLIN ++ NI PM++L+HWD
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 454
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ LQ++GG+ NP + D F+ Y F GDRVK W+TFNEP + + GYGS E P
Sbjct: 455 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 514
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGG 731
+ Y A ++ AHA+ Y Y+ +++ +Q G
Sbjct: 515 VKDPGWAPYRIAHTVIKAHARVYHTYDEKYRQEQKG 550
Score = 215 bits (526), Expect = 1e-55
Identities = 92/181 (50%), Positives = 129/181 (71%)
Frame = +3
Query: 81 RFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVER 260
RFP+ F++ A+A+YQIEGAW DGKG +IWD +H P + +++ GD+A DSYH +
Sbjct: 808 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 866
Query: 261 DVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHW 440
D+ ++ LG+ YRFS+SWSRILP G +NEAG++YY RLI+ +L +I P +++YHW
Sbjct: 867 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 926
Query: 441 DLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
DLPQ LQ++GG+ N I F++Y V+F +LGD+VK WIT NEP V+ YQGYG AP
Sbjct: 927 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 986
Query: 621 M 623
+
Sbjct: 987 V 987
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 246 bits (601), Expect = 9e-65
Identities = 105/216 (48%), Positives = 145/216 (67%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
F DDFL+G ++++YQIEGAWD DGKG +IWD TH + + D + GDIA DSYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ M+R L + YRFS+SWSRI P+G + +N GVDYYNRLIN ++ NI PM++L+HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ LQ++GG+ NP + D F+ Y F GDRVK W+TFNEP + + GYGS E P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGG 731
+ Y A ++ AHA+ Y Y+ +++ +Q G
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKG 1118
Score = 245 bits (600), Expect = 1e-64
Identities = 108/223 (48%), Positives = 152/223 (68%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 RFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVER 260
RFP+ F++ A+A+YQIEGAW DGKG +IWD +H P + +++ GD+A DSYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHW 440
D+ ++ LG+ YRFS+SWSRILP G +NEAG++YY RLI+ +L +I P +++YHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
DLPQ LQ++GG+ N I F++Y V+F +LGD+VK WIT NEP V+ YQGYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -MLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ N Y+ NL+ AHA+A+ LYN+ ++ QGG IT
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISIT 1597
Score = 204 bits (498), Expect = 3e-52
Identities = 94/223 (42%), Positives = 137/223 (61%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNV 254
Q FP+ FL+G +T ++ +EG W E G+G +IWD N T ++ ++A+DSYH V
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTT--EGQATLEVASDSYHKV 436
Query: 255 ERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLY 434
DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + I PM +L+
Sbjct: 437 ASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLF 496
Query: 435 HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEK 614
HWDLPQ LQ+ GG+ N + D F DY F+ GDRVKLW+TF+EP V+ Y GYG+ +
Sbjct: 497 HWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQH 556
Query: 615 APMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
P ++ V ++ A +L AHA+ + YN+ + +Q G GI
Sbjct: 557 PPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGI 599
Score = 64.9 bits (151), Expect = 3e-10
Identities = 45/150 (30%), Positives = 68/150 (45%), Gaps = 1/150 (0%)
Frame = +3
Query: 297 YRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWDLP-QKLQELGG 473
Y+ +SW+++LP+G +E V Y RL+ + + PM+ L+H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPMLNATAVGTYM 653
F AD F DY F GD V +W TF++ V + +A L
Sbjct: 147 F-----ADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQL--------- 192
Query: 654 CARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
+ L AH KAY +Y+ + QGG+ I
Sbjct: 193 --QTLSDAHRKAYEIYHESY-AFQGGKLSI 219
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 246 bits (601), Expect = 9e-65
Identities = 105/216 (48%), Positives = 145/216 (67%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
F DDFL+G ++++YQIEGAWD DGKG +IWD TH + + D + GDIA DSYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ M+R L + YRFS+SWSRI P+G + +N GVDYYNRLIN ++ NI PM++L+HWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ LQ++GG+ NP + D F+ Y F GDRVK W+TFNEP + + GYGS E P
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGSGEFPPG 1082
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGG 731
+ Y A ++ AHA+ Y Y+ +++ +Q G
Sbjct: 1083 VKDPGWAPYRIAHAVIKAHARVYHTYDEKYRQEQKG 1118
Score = 245 bits (600), Expect = 1e-64
Identities = 108/223 (48%), Positives = 152/223 (68%), Gaps = 1/223 (0%)
Frame = +3
Query: 81 RFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVER 260
RFP+ F++ A+A+YQIEGAW DGKG +IWD +H P + +++ GD+A DSYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHW 440
D+ ++ LG+ YRFS+SWSRILP G +NEAG++YY RLI+ +L +I P +++YHW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
DLPQ LQ++GG+ N I F++Y V+F +LGD+VK WIT NEP V+ YQGYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -MLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ N Y+ NL+ AHA+A+ LYN+ ++ QGG IT
Sbjct: 1555 GVSNRPGTAPYIVGHNLIKAHAEAWHLYNDVYRASQGGVISIT 1597
Score = 204 bits (498), Expect = 3e-52
Identities = 94/223 (42%), Positives = 137/223 (61%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNV 254
Q FP+ FL+G +T ++ +EG W E G+G +IWD N T ++ ++A+DSYH V
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWDPRRPLNTT--EGQATLEVASDSYHKV 436
Query: 255 ERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLY 434
DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + I PM +L+
Sbjct: 437 ASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLF 496
Query: 435 HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEK 614
HWDLPQ LQ+ GG+ N + D F DY F+ GDRVKLW+TF+EP V+ Y GYG+ +
Sbjct: 497 HWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQH 556
Query: 615 APMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
P ++ V ++ A +L AHA+ + YN+ + +Q G GI
Sbjct: 557 PPGISDPGVASFKVAHLVLKAHARTWHHYNSHHRPQQQGHVGI 599
Score = 64.5 bits (150), Expect = 4e-10
Identities = 44/150 (29%), Positives = 68/150 (45%), Gaps = 1/150 (0%)
Frame = +3
Query: 297 YRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWDLP-QKLQELGG 473
Y+ +SW+++LP+G +E V Y RL+ + + PM+ L+H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPMLNATAVGTYM 653
F AD F DY F GD V +W TF++ V + +A L
Sbjct: 147 F-----ADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKELPHQESRASQL--------- 192
Query: 654 CARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
+ L AH KAY +Y+ + QGG+ +
Sbjct: 193 --QTLSDAHRKAYEIYHESY-AFQGGKLSV 219
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 225 bits (549), Expect = 2e-58
Identities = 98/223 (43%), Positives = 148/223 (66%), Gaps = 2/223 (0%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F +G +++YQ EGAWD+DGKG +IWD TH+ + D+A D Y+ V+ D
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGF-ANEVNEAGVDYYNRLINEMLKYNITPMISLYHW 440
+ ++REL ++ YRFS+SW R+LP+G A +VN+ G+++Y+ LI+ +L NITP+++L+HW
Sbjct: 97 IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156
Query: 441 DLPQKLQ-ELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKA 617
DLPQ LQ + GG+ N +A++F DY + F GDRVK WITF++PR + +GY + A
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHA 216
Query: 618 PMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
P L G Y A +++ AHAK + YN +++KQ G GI+
Sbjct: 217 PGLKLRGTGLYKAAHHIIKAHAKTWHSYNTTWRSKQQGLVGIS 259
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 223 bits (544), Expect = 7e-58
Identities = 107/239 (44%), Positives = 144/239 (60%), Gaps = 16/239 (6%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESN----------- 221
Q FPD FL+ +A+YQ EG W + GKG +IWD TH+ D N
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 222 ----GDIAADSYHNVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLI 389
GD+A+DSY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYNITPMISLYHWDLPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITF 566
+ + + P+++LYHWDLPQ+LQ+ GG+AN +AD F DY + F G +VK WIT
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPRVVCYQGYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
+ P VV + GY + AP + + Y+ A NLLLAHAK + LYN F+ QGGQ I
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSI 296
Score = 102 bits (244), Expect = 2e-21
Identities = 68/229 (29%), Positives = 113/229 (49%), Gaps = 9/229 (3%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSY----HN 251
FP DF +G Q++ + N++ + H++ +I + SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQF-TDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAA 577
Query: 252 VERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISL 431
++ + +++E+ + +RFS+ W+ ILP G ++VN + YY + +E+++ NITP+++L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 432 Y-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQG 596
+ + LP+ L G + NP A F +Y R+ F +LG VKLWIT NEP
Sbjct: 638 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------- 690
Query: 597 YGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
T TY NLL AHA A+ +YN +F+ Q G+ I
Sbjct: 691 -----------YTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISI 728
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 223 bits (544), Expect = 7e-58
Identities = 107/239 (44%), Positives = 144/239 (60%), Gaps = 16/239 (6%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESN----------- 221
Q FPD FL+ +A+YQ EG W + GKG +IWD TH+ D N
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 222 ----GDIAADSYHNVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLI 389
GD+A+DSY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYNITPMISLYHWDLPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITF 566
+ + + P+++LYHWDLPQ+LQ+ GG+AN +AD F DY + F G +VK WIT
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPRVVCYQGYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
+ P VV + GY + AP + + Y+ A NLLLAHAK + LYN F+ QGGQ I
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSI 296
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 223 bits (544), Expect = 7e-58
Identities = 107/239 (44%), Positives = 144/239 (60%), Gaps = 16/239 (6%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESN----------- 221
Q FPD FL+ +A+YQ EG W + GKG +IWD TH+ D N
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 222 ----GDIAADSYHNVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLI 389
GD+A+DSY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYNITPMISLYHWDLPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITF 566
+ + + P+++LYHWDLPQ+LQ+ GG+AN +AD F DY + F G +VK WIT
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPRVVCYQGYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
+ P VV + GY + AP + + Y+ A NLLLAHAK + LYN F+ QGGQ I
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSI 296
Score = 102 bits (244), Expect = 2e-21
Identities = 68/229 (29%), Positives = 113/229 (49%), Gaps = 9/229 (3%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSY----HN 251
FP DF +G Q++ + N++ + H++ +I + SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQF-TDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAA 577
Query: 252 VERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISL 431
++ + +++E+ + +RFS+ W+ ILP G ++VN + YY + +E+++ NITP+++L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 432 Y-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQG 596
+ + LP+ L G + NP A F +Y R+ F +LG VKLWIT NEP
Sbjct: 638 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------- 690
Query: 597 YGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
T TY NLL AHA A+ +YN +F+ Q G+ I
Sbjct: 691 -----------YTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISI 728
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 223 bits (544), Expect = 7e-58
Identities = 107/239 (44%), Positives = 144/239 (60%), Gaps = 16/239 (6%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESN----------- 221
Q FPD FL+ +A+YQ EG W + GKG +IWD TH+ D N
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 222 ----GDIAADSYHNVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLI 389
GD+A+DSY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYNITPMISLYHWDLPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITF 566
+ + + P+++LYHWDLPQ+LQ+ GG+AN +AD F DY + F G +VK WIT
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPRVVCYQGYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
+ P VV + GY + AP + + Y+ A NLLLAHAK + LYN F+ QGGQ I
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLLAHAKVWHLYNTSFRPTQGGQVSI 296
Score = 102 bits (244), Expect = 2e-21
Identities = 68/229 (29%), Positives = 113/229 (49%), Gaps = 9/229 (3%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSY----HN 251
FP DF +G Q++ + N++ + H++ +I + SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQF-TDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAA 577
Query: 252 VERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISL 431
++ + +++E+ + +RFS+ W+ ILP G ++VN + YY + +E+++ NITP+++L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 432 Y-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQG 596
+ + LP+ L G + NP A F +Y R+ F +LG VKLWIT NEP
Sbjct: 638 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------- 690
Query: 597 YGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
T TY NLL AHA A+ +YN +F+ Q G+ I
Sbjct: 691 -----------YTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISI 728
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 210 bits (512), Expect = 5e-54
Identities = 92/221 (41%), Positives = 137/221 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ G Y A NL+ AHA+++ Y++ F+ KQ G ++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLS 223
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 210 bits (512), Expect = 5e-54
Identities = 92/221 (41%), Positives = 137/221 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ G Y A NL+ AHA+++ Y++ F+ KQ G ++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLS 223
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 210 bits (512), Expect = 5e-54
Identities = 92/221 (41%), Positives = 137/221 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ G Y A NL+ AHA+++ Y++ F+ KQ G ++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLS 223
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 210 bits (512), Expect = 5e-54
Identities = 92/221 (41%), Positives = 137/221 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ G Y A NL+ AHA+++ Y++ F+ KQ G ++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLS 223
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 210 bits (512), Expect = 5e-54
Identities = 92/221 (41%), Positives = 137/221 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ G Y A NL+ AHA+++ Y++ F+ KQ G ++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLS 223
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 209 bits (510), Expect = 9e-54
Identities = 92/221 (41%), Positives = 137/221 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
++ +++LGL YRFS+SWSR+LP G +N+ G+DYYN++I+++LK +TP+++LYH+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAPM 623
LPQ L++ GG+ + I + F+ Y + F+ GDRVK WIT NE V+ Y P
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSYDLGMFPPG 182
Query: 624 LNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ G Y A NL+ AHA+++ Y++ F+ KQ G ++
Sbjct: 183 IPHFGTGGYQAAHNLIKAHARSWHSYDSLFRKKQKGMVSLS 223
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 194 bits (473), Expect = 3e-49
Identities = 94/216 (43%), Positives = 129/216 (59%), Gaps = 16/216 (7%)
Frame = +3
Query: 75 QRRFPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESN----------- 221
Q FPD FL+ +A+YQ EG W + GKG +IWD TH+ D N
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 222 ----GDIAADSYHNVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLI 389
GD+A+DSY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYNITPMISLYHWDLPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITF 566
+ + + P+++LYHWDLPQ+LQ+ GG+AN +AD F DY + F G +VK WIT
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPRVVCYQGYGSTEKAPMLNATAVGTYMCARNLLL 674
+ P VV + GY + AP + + Y+ A NLLL
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVAHNLLL 273
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 192 bits (468), Expect = 1e-48
Identities = 88/222 (39%), Positives = 129/222 (58%), Gaps = 1/222 (0%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP +F +G T + Q+EG+W +DGKG +IWD+ H + ++ +NG ++DSY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ NI P+++LYHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
LP LQE GG+ N I D F DY F GDRVK WIT + P +V + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 621 MLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
Y NL+ AH+K + YN F+ Q G IT
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSIT 299
Score = 117 bits (281), Expect = 5e-26
Identities = 61/171 (35%), Positives = 97/171 (56%), Gaps = 5/171 (2%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMIS 428
N+++ +EM+ + + YRF++ W+ +LP+G + VN + YY +++E LK I+ M++
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LY-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQ 593
LY H LP+ L G+ NP A+ F+ Y + F +LGD VKLWIT NEP
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEP------ 694
Query: 594 GYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ + N + TY A NLL+AHA A+RLY+ +F+ Q G ++
Sbjct: 695 ----NRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLS 741
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 192 bits (468), Expect = 1e-48
Identities = 88/222 (39%), Positives = 129/222 (58%), Gaps = 1/222 (0%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP +F +G T + Q+EG+W +DGKG +IWD+ H + ++ +NG ++DSY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ NI P+++LYHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
LP LQE GG+ N I D F DY F GDRVK WIT + P +V + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 621 MLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
Y NL+ AH+K + YN F+ Q G IT
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSIT 299
Score = 117 bits (281), Expect = 5e-26
Identities = 61/171 (35%), Positives = 97/171 (56%), Gaps = 5/171 (2%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMIS 428
N+++ +EM+ + + YRF++ W+ +LP+G + VN + YY +++E LK I+ M++
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LY-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQ 593
LY H LP+ L G+ NP A+ F+ Y + F +LGD VKLWIT NEP
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEP------ 694
Query: 594 GYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ + N + TY A NLL+AHA A+RLY+ +F+ Q G ++
Sbjct: 695 ----NRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLS 741
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 192 bits (468), Expect = 1e-48
Identities = 88/222 (39%), Positives = 129/222 (58%), Gaps = 1/222 (0%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP +F +G T + Q+EG+W +DGKG +IWD+ H + ++ +NG ++DSY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTHLKNVSS-TNG--SSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISLYHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ NI P+++LYHWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQGYGSTEKAP 620
LP LQE GG+ N I D F DY F GDRVK WIT + P +V + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Query: 621 MLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
Y NL+ AH+K + YN F+ Q G IT
Sbjct: 258 GEKGNLAAVYTVGHNLIKAHSKVWHNYNTHFRPHQKGWLSIT 299
Score = 117 bits (281), Expect = 5e-26
Identities = 61/171 (35%), Positives = 97/171 (56%), Gaps = 5/171 (2%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMIS 428
N+++ +EM+ + + YRF++ W+ +LP+G + VN + YY +++E LK I+ M++
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LY-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQ 593
LY H LP+ L G+ NP A+ F+ Y + F +LGD VKLWIT NEP
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEP------ 694
Query: 594 GYGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGIT 746
+ + N + TY A NLL+AHA A+RLY+ +F+ Q G ++
Sbjct: 695 ----NRLSDIYNRSGNDTYGAAHNLLVAHALAWRLYDRQFRPSQRGAVSLS 741
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 102 bits (244), Expect = 2e-21
Identities = 68/229 (29%), Positives = 113/229 (49%), Gaps = 9/229 (3%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSY----HN 251
FP DF +G Q++ + N++ + H++ +I + SY
Sbjct: 246 FPCDFAWGVVDNYIQVDTTLSQF-TDLNVYLWDVHHSKRLIKVDGVVTKKRKSYCVDFAA 304
Query: 252 VERDVEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGVDYYNRLINEMLKYNITPMISL 431
++ + +++E+ + +RFS+ W+ ILP G ++VN + YY + +E+++ NITP+++L
Sbjct: 305 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 364
Query: 432 Y-----HWDLPQKLQELGGFANPLIADWFEDYVRVVFAKLGDRVKLWITFNEPRVVCYQG 596
+ + LP+ L G + NP A F +Y R+ F +LG VKLWIT NEP
Sbjct: 365 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEP------- 417
Query: 597 YGSTEKAPMLNATAVGTYMCARNLLLAHAKAYRLYNNEFKTKQGGQCGI 743
T TY NLL AHA A+ +YN +F+ Q G+ I
Sbjct: 418 -----------YTRNMTYSAGHNLLKAHALAWHVYNEKFRHAQNGKISI 455
Score = 32.7 bits (71), Expect = 1.4
Identities = 13/23 (56%), Positives = 15/23 (65%)
Frame = +3
Query: 675 AHAKAYRLYNNEFKTKQGGQCGI 743
AHAK + LYN F+ QGGQ I
Sbjct: 1 AHAKVWHLYNTSFRPTQGGQVSI 23
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 98.7 bits (235), Expect = 2e-20
Identities = 42/95 (44%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGV 368
++ +++LGL YRFS+SWSR+LP G +N+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 98.7 bits (235), Expect = 2e-20
Identities = 42/95 (44%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGV 368
++ +++LGL YRFS+SWSR+LP G +N+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 97.9 bits (233), Expect = 3e-20
Identities = 42/95 (44%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLFGTATASYQIEGAWDEDGKGENIWDYMTHNNPTVIADESNGDIAADSYHNVERD 263
FP F + ATA+YQ+EG WD DGKG +WD TH + GD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSVSWSRILPSGFANEVNEAGV 368
++ +++LGL YRFS+SWSR+LP G +N+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 118,688,052
Number of Sequences: 237096
Number of extensions: 2521584
Number of successful extensions: 10664
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 10047
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 10628
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9015132854
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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