Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV17d11f
(421 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M77836-1|AAA36407.1| 319|Homo sapiens pyrroline-5-carboxylate r... 68 1e-11
CR541769-1|CAG46568.1| 319|Homo sapiens PYCR1 protein. 68 1e-11
BC071842-1|AAH71842.1| 319|Homo sapiens pyrroline-5-carboxylate... 68 1e-11
BC022244-1|AAH22244.1| 171|Homo sapiens PYCR1 protein protein. 68 1e-11
BC020553-1|AAH20553.1| 320|Homo sapiens pyrroline-5-carboxylate... 68 1e-11
BC014868-1|AAH14868.1| 320|Homo sapiens pyrroline-5-carboxylate... 68 1e-11
BC007993-1|AAH07993.1| 274|Homo sapiens pyrroline-5-carboxylate... 68 1e-11
BC001504-1|AAH01504.1| 319|Homo sapiens pyrroline-5-carboxylate... 68 1e-11
AL833857-1|CAD38716.1| 244|Homo sapiens hypothetical protein pr... 68 1e-11
AL117348-6|CAI21802.1| 320|Homo sapiens pyrroline-5-carboxylate... 68 1e-11
AL117348-5|CAI21801.1| 214|Homo sapiens pyrroline-5-carboxylate... 68 1e-11
AK222685-1|BAD96405.1| 276|Homo sapiens Pyrroline-5-carboxylate... 68 1e-11
AK023914-1|BAB14721.1| 274|Homo sapiens protein ( Homo sapiens ... 68 1e-11
AF151351-1|AAD34611.1| 319|Homo sapiens pyrroline 5-carboxylate... 68 1e-11
AF087859-1|AAP97169.1| 320|Homo sapiens pyrroline 5-carboxylate... 68 1e-11
AY513285-1|AAT08038.1| 199|Homo sapiens proliferation-inducing ... 67 2e-11
AF218000-1|AAG17242.1| 272|Homo sapiens unknown protein. 40 0.004
AK129846-1|BAC85241.1| 236|Homo sapiens protein ( Homo sapiens ... 36 0.042
AK127397-1|BAC86958.1| 130|Homo sapiens protein ( Homo sapiens ... 36 0.073
AK126213-1|BAC86488.1| 262|Homo sapiens protein ( Homo sapiens ... 36 0.073
AK128694-1|BAC87575.1| 291|Homo sapiens protein ( Homo sapiens ... 32 0.90
AK124805-1|BAC85954.1| 189|Homo sapiens protein ( Homo sapiens ... 31 2.1
>M77836-1|AAA36407.1| 319|Homo sapiens pyrroline-5-carboxylate
reductase protein.
Length = 319
Score = 68.1 bits (159), Expect = 1e-11
Identities = 29/58 (50%), Positives = 43/58 (74%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
+ ++ALADG VK G+PR +A+R AQ ++G+ +M+L + +HPG LKD V SP G+TI
Sbjct: 182 FTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATI 239
>CR541769-1|CAG46568.1| 319|Homo sapiens PYCR1 protein.
Length = 319
Score = 68.1 bits (159), Expect = 1e-11
Identities = 29/58 (50%), Positives = 43/58 (74%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
+ ++ALADG VK G+PR +A+R AQ ++G+ +M+L + +HPG LKD V SP G+TI
Sbjct: 182 FTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATI 239
>BC071842-1|AAH71842.1| 319|Homo sapiens pyrroline-5-carboxylate
reductase 1 protein.
Length = 319
Score = 68.1 bits (159), Expect = 1e-11
Identities = 29/58 (50%), Positives = 43/58 (74%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
+ ++ALADG VK G+PR +A+R AQ ++G+ +M+L + +HPG LKD V SP G+TI
Sbjct: 182 FTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATI 239
>BC022244-1|AAH22244.1| 171|Homo sapiens PYCR1 protein protein.
Length = 171
Score = 68.1 bits (159), Expect = 1e-11
Identities = 29/58 (50%), Positives = 43/58 (74%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
+ ++ALADG VK G+PR +A+R AQ ++G+ +M+L + +HPG LKD V SP G+TI
Sbjct: 34 FTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATI 91
>BC020553-1|AAH20553.1| 320|Homo sapiens pyrroline-5-carboxylate
reductase family, member 2 protein.
Length = 320
Score = 68.1 bits (159), Expect = 1e-11
Identities = 28/58 (48%), Positives = 44/58 (75%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
++ ++ALADG VK G+PR +A++ AQ ++G+ +M+L + +HP LKD VCSP G+TI
Sbjct: 182 FMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATI 239
>BC014868-1|AAH14868.1| 320|Homo sapiens pyrroline-5-carboxylate
reductase family, member 2 protein.
Length = 320
Score = 68.1 bits (159), Expect = 1e-11
Identities = 28/58 (48%), Positives = 44/58 (75%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
++ ++ALADG VK G+PR +A++ AQ ++G+ +M+L + +HP LKD VCSP G+TI
Sbjct: 182 FMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATI 239
>BC007993-1|AAH07993.1| 274|Homo sapiens pyrroline-5-carboxylate
reductase-like protein.
Length = 274
Score = 68.1 bits (159), Expect = 1e-11
Identities = 29/57 (50%), Positives = 44/57 (77%)
Frame = -1
Query: 175 EALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTICGV 5
EALA+GAVK G+P ++A R AAQ ++G+ +M+L G+HP L+ +VC+P G+TI G+
Sbjct: 189 EALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGTTIYGL 245
>BC001504-1|AAH01504.1| 319|Homo sapiens pyrroline-5-carboxylate
reductase 1 protein.
Length = 319
Score = 68.1 bits (159), Expect = 1e-11
Identities = 29/58 (50%), Positives = 43/58 (74%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
+ ++ALADG VK G+PR +A+R AQ ++G+ +M+L + +HPG LKD V SP G+TI
Sbjct: 182 FTALDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATI 239
>AL833857-1|CAD38716.1| 244|Homo sapiens hypothetical protein
protein.
Length = 244
Score = 68.1 bits (159), Expect = 1e-11
Identities = 29/57 (50%), Positives = 44/57 (77%)
Frame = -1
Query: 175 EALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTICGV 5
EALA+GAVK G+P ++A R AAQ ++G+ +M+L G+HP L+ +VC+P G+TI G+
Sbjct: 159 EALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGTTIYGL 215
>AL117348-6|CAI21802.1| 320|Homo sapiens pyrroline-5-carboxylate
reductase family, member 2 protein.
Length = 320
Score = 68.1 bits (159), Expect = 1e-11
Identities = 28/58 (48%), Positives = 44/58 (75%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
++ ++ALADG VK G+PR +A++ AQ ++G+ +M+L + +HP LKD VCSP G+TI
Sbjct: 182 FMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATI 239
>AL117348-5|CAI21801.1| 214|Homo sapiens pyrroline-5-carboxylate
reductase family, member 2 protein.
Length = 214
Score = 68.1 bits (159), Expect = 1e-11
Identities = 28/58 (48%), Positives = 44/58 (75%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
++ ++ALADG VK G+PR +A++ AQ ++G+ +M+L + +HP LKD VCSP G+TI
Sbjct: 135 FMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATI 192
>AK222685-1|BAD96405.1| 276|Homo sapiens Pyrroline-5-carboxylate
reductase-like variant protein.
Length = 276
Score = 68.1 bits (159), Expect = 1e-11
Identities = 29/57 (50%), Positives = 44/57 (77%)
Frame = -1
Query: 175 EALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTICGV 5
EALA+GAVK G+P ++A R AAQ ++G+ +M+L G+HP L+ +VC+P G+TI G+
Sbjct: 201 EALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGTTIYGL 257
>AK023914-1|BAB14721.1| 274|Homo sapiens protein ( Homo sapiens
cDNA FLJ13852 fis, clone THYRO1000934, weakly similar to
PYRROLINE-5-CARBOXYLATE REDUCTASE (EC 1.5.1.2). ).
Length = 274
Score = 68.1 bits (159), Expect = 1e-11
Identities = 29/57 (50%), Positives = 44/57 (77%)
Frame = -1
Query: 175 EALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTICGV 5
EALA+GAVK G+P ++A R AAQ ++G+ +M+L G+HP L+ +VC+P G+TI G+
Sbjct: 189 EALAEGAVKMGMPSSLAHRIAAQTLLGTAKMLLHEGQHPAQLRSDVCTPGGTTIYGL 245
>AF151351-1|AAD34611.1| 319|Homo sapiens pyrroline 5-carboxylate
reductase isoform protein.
Length = 319
Score = 68.1 bits (159), Expect = 1e-11
Identities = 28/58 (48%), Positives = 44/58 (75%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
++ ++ALADG VK G+PR +A++ AQ ++G+ +M+L + +HP LKD VCSP G+TI
Sbjct: 181 FMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATI 238
>AF087859-1|AAP97169.1| 320|Homo sapiens pyrroline 5-carboxylate
reductase protein.
Length = 320
Score = 68.1 bits (159), Expect = 1e-11
Identities = 28/58 (48%), Positives = 44/58 (75%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
++ ++ALADG VK G+PR +A++ AQ ++G+ +M+L + +HP LKD VCSP G+TI
Sbjct: 182 FMALDALADGGVKMGLPRRLAIQLGAQALLGAAKMLLDSEQHPCQLKDNVCSPGGATI 239
>AY513285-1|AAT08038.1| 199|Homo sapiens proliferation-inducing
protein 45 protein.
Length = 199
Score = 67.3 bits (157), Expect = 2e-11
Identities = 29/55 (52%), Positives = 42/55 (76%)
Frame = -1
Query: 178 IEALADGAVKQGVPRAMALRHAAQVVVGSGQMVLQTGKHPGLLKDEVCSPAGSTI 14
++ALADG VK G+PR +A+R AQ ++G+ +M+L + +HPG LKD V SP G+TI
Sbjct: 65 LDALADGGVKMGLPRRLAVRLGAQALLGAAKMLLHSEQHPGQLKDNVSSPGGATI 119
>AF218000-1|AAG17242.1| 272|Homo sapiens unknown protein.
Length = 272
Score = 39.5 bits (88), Expect = 0.004
Identities = 19/45 (42%), Positives = 29/45 (64%), Gaps = 2/45 (4%)
Frame = -1
Query: 187 YIVIEALADGAVKQGVPRAMALRHAAQVVVGSGQ--MVLQTGKHP 59
+ ++ALADG VK G+PR +A+R AQ ++G+ Q L+T P
Sbjct: 182 FTALDALADGGVKMGLPRRLAVRLGAQALLGACQDAAALRTAPRP 226
>AK129846-1|BAC85241.1| 236|Homo sapiens protein ( Homo sapiens
cDNA FLJ26336 fis, clone HRT02842. ).
Length = 236
Score = 36.3 bits (80), Expect = 0.042
Identities = 20/63 (31%), Positives = 31/63 (49%), Gaps = 3/63 (4%)
Frame = +1
Query: 196 TFEYSYLKIAVFFLFRGFKHNYDYTCFFFLSQKFVICSVYIFTTICLHVHIFI---KFLH 366
T+ YSY +I + H Y Y C F + VY +T IC+H++I I +++
Sbjct: 3 TYVYSYTRICIHMYIH--IHAYAYICIFIYTHMHTY--VYSYTRICIHMYIHIHAYAYIY 58
Query: 367 FYS 375
YS
Sbjct: 59 VYS 61
Score = 36.3 bits (80), Expect = 0.042
Identities = 17/67 (25%), Positives = 34/67 (50%), Gaps = 3/67 (4%)
Frame = +1
Query: 199 FEYSYLKIAVFFLFRGFKHNYDYTCFFFLSQKFVICSVYIFTTICLHVHIFI---KFLHF 369
+ YSY +I + + H + Y + ++ VY +T IC+H+ +FI +++
Sbjct: 58 YVYSYTRICIHICIFIYTHMHTYMYIHIHAYAYIY--VYSYTRICIHICVFICTHAYIYV 115
Query: 370 YSQLLCL 390
YS + C+
Sbjct: 116 YSYVQCM 122
Score = 29.5 bits (63), Expect = 4.8
Identities = 10/20 (50%), Positives = 12/20 (60%)
Frame = +3
Query: 294 ICNMLCLHFYDHLFTCSHFY 353
IC C H Y +FTC+H Y
Sbjct: 154 ICVFTCTHVYISVFTCTHVY 173
>AK127397-1|BAC86958.1| 130|Homo sapiens protein ( Homo sapiens
cDNA FLJ45488 fis, clone BRTHA2003759. ).
Length = 130
Score = 35.5 bits (78), Expect = 0.073
Identities = 17/65 (26%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
Frame = +1
Query: 199 FEYSYLKIAVFFLFRGFKHNYDYTCFFFLSQKFVICSVYIFTTICLHVHIFIKFLHFYSQ 378
+ Y Y+ + ++F + + Y + + ++ +YIFT I +++HIFI +LH +
Sbjct: 28 YVYVYIYLYIYFYIFTYIYLYIFIYIYICLYIYLYIYLYIFTYIYIYLHIFI-YLHIFIY 86
Query: 379 L-LCL 390
+ +CL
Sbjct: 87 ICICL 91
>AK126213-1|BAC86488.1| 262|Homo sapiens protein ( Homo sapiens
cDNA FLJ44225 fis, clone THYMU3006168. ).
Length = 262
Score = 35.5 bits (78), Expect = 0.073
Identities = 17/53 (32%), Positives = 26/53 (49%)
Frame = +1
Query: 196 TFEYSYLKIAVFFLFRGFKHNYDYTCFFFLSQKFVICSVYIFTTICLHVHIFI 354
T+ YSY +I + + H + Y C + VY +T IC+H+ IFI
Sbjct: 119 TYVYSYARICIHM----YIHIHAYACICMFMYAHMRAYVYSYTRICIHICIFI 167
Score = 33.5 bits (73), Expect = 0.29
Identities = 16/53 (30%), Positives = 25/53 (47%)
Frame = +1
Query: 196 TFEYSYLKIAVFFLFRGFKHNYDYTCFFFLSQKFVICSVYIFTTICLHVHIFI 354
T+ YSY ++ + H Y Y C F + VY + IC+H++I I
Sbjct: 87 TYVYSYARVCIHMYIH--IHAYAYICIFIYTHMHTY--VYSYARICIHMYIHI 135
>AK128694-1|BAC87575.1| 291|Homo sapiens protein ( Homo sapiens
cDNA FLJ46861 fis, clone UTERU3011092. ).
Length = 291
Score = 31.9 bits (69), Expect = 0.90
Identities = 21/70 (30%), Positives = 30/70 (42%), Gaps = 11/70 (15%)
Frame = +1
Query: 196 TFEYSYLKIAVFFLFRGFKHNYDYTCFFFLSQK----------FVICSVYIFTTICLHVH 345
T+ YSY +I + H Y Y C F + + VY +T IC+H+
Sbjct: 67 TYVYSYTRICIHMYVH--IHAYAYICIFIYTHMHTYMYIHMHAYAYIYVYSYTRICIHIC 124
Query: 346 IFI-KFLHFY 372
IFI +H Y
Sbjct: 125 IFICTHMHTY 134
Score = 30.3 bits (65), Expect = 2.7
Identities = 15/50 (30%), Positives = 23/50 (46%)
Frame = +1
Query: 205 YSYLKIAVFFLFRGFKHNYDYTCFFFLSQKFVICSVYIFTTICLHVHIFI 354
YS +I + H Y Y C F + VY +T IC+H+++ I
Sbjct: 38 YSCTRICIHMYIH--MHAYAYICIFICTHMHTY--VYSYTRICIHMYVHI 83
Score = 29.1 bits (62), Expect = 6.3
Identities = 15/63 (23%), Positives = 27/63 (42%)
Frame = +1
Query: 199 FEYSYLKIAVFFLFRGFKHNYDYTCFFFLSQKFVICSVYIFTTICLHVHIFIKFLHFYSQ 378
+ YSY +I + + H + Y C + VY T IC+H++I + +
Sbjct: 4 YVYSYARICMHM----YIHIHAYACMCIFIYTHMHACVYSCTRICIHMYIHMHAYAYICI 59
Query: 379 LLC 387
+C
Sbjct: 60 FIC 62
>AK124805-1|BAC85954.1| 189|Homo sapiens protein ( Homo sapiens
cDNA FLJ42815 fis, clone BRCAN2014143. ).
Length = 189
Score = 30.7 bits (66), Expect = 2.1
Identities = 10/49 (20%), Positives = 26/49 (53%)
Frame = +1
Query: 205 YSYLKIAVFFLFRGFKHNYDYTCFFFLSQKFVICSVYIFTTICLHVHIF 351
++Y+ + V+ + H Y C + ++ ++I+ +C++VHI+
Sbjct: 2 HTYIYMCVYPYICIYMHVYPCICIYLHVYTYICMYIHIYPYLCMYVHIY 50
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 58,487,727
Number of Sequences: 237096
Number of extensions: 1201015
Number of successful extensions: 2562
Number of sequences better than 10.0: 22
Number of HSP's better than 10.0 without gapping: 2388
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2539
length of database: 76,859,062
effective HSP length: 83
effective length of database: 57,180,094
effective search space used: 3202085264
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -