Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV16f04f
(765 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for ... 214 3e-55
X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for ... 214 3e-55
M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase E1... 214 3e-55
M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate ... 214 3e-55
L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase E1... 214 3e-55
J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase al... 214 3e-55
J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein. 214 3e-55
D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase al... 214 3e-55
BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase ... 214 3e-55
AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase ... 214 3e-55
AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase ... 214 3e-55
AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase ... 214 3e-55
EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1 pro... 209 7e-54
AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase ... 204 2e-52
M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase co... 199 1e-50
BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase ... 199 1e-50
BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase ... 199 1e-50
BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase ... 199 1e-50
BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase ... 199 1e-50
BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein. 199 1e-50
BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase ... 199 1e-50
BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase ... 198 2e-50
AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase ... 188 1e-47
AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase ... 176 6e-44
EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein. 100 7e-21
L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase E1... 99 2e-20
AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase ... 77 9e-14
BC150265-1|AAI50266.1| 1481|Homo sapiens CRKRS protein protein. 40 0.007
AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein. 40 0.007
AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein. 40 0.007
AM746210-1|CAN88919.1| 302|Homo sapiens PDHA1/LOC79064 protein ... 35 0.37
BC052955-1|AAH52955.1| 505|Homo sapiens Wiskott-Aldrich syndrom... 34 0.48
AC006333-1|AAQ96857.1| 505|Homo sapiens unknown protein. 34 0.48
AM295156-1|CAL26602.1| 505|Homo sapiens WASL protein protein. 34 0.64
D88460-1|BAA20128.1| 505|Homo sapiens N-WASP protein. 32 2.0
BC039878-1|AAH39878.1| 825|Homo sapiens chromosome 14 open read... 32 2.6
AJ420811-1|CAD12730.1| 344|Homo sapiens ADAMTS-13 protein, trun... 32 2.6
Y13440-1|CAA73851.1| 582|Homo sapiens Rox protein. 31 3.4
Y11354-1|CAA72189.1| 1083|Homo sapiens subunit of RNA polymerase... 31 3.4
X96401-1|CAA65265.1| 582|Homo sapiens ROX protein protein. 31 3.4
BC117563-1|AAI17564.1| 582|Homo sapiens MAX binding protein pro... 31 3.4
AY623115-1|AAT38111.1| 1085|Homo sapiens TAF4 RNA polymerase II,... 31 3.4
AL137077-2|CAI11045.1| 1085|Homo sapiens TAF4 RNA polymerase II,... 31 3.4
AL109911-2|CAI19182.1| 1085|Homo sapiens TAF4 RNA polymerase II,... 31 3.4
AK130326-1|BAC85327.1| 508|Homo sapiens protein ( Homo sapiens ... 31 3.4
AL611964-2|CAH73872.1| 495|Homo sapiens REST corepressor 3 prot... 31 4.5
AL590101-2|CAH72433.1| 495|Homo sapiens REST corepressor 3 prot... 31 4.5
AK001738-1|BAA91872.1| 495|Homo sapiens protein ( Homo sapiens ... 31 4.5
AB037764-1|BAA92581.1| 520|Homo sapiens KIAA1343 protein protein. 31 4.5
AK025837-1|BAB15254.1| 616|Homo sapiens protein ( Homo sapiens ... 31 6.0
BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein. 30 7.9
AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B prot... 30 7.9
AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal ... 30 7.9
AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal ... 30 7.9
AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and ... 30 7.9
AB058759-1|BAB47485.1| 1134|Homo sapiens KIAA1856 protein protein. 30 7.9
AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein. 30 7.9
>X52710-1|CAA36934.1| 390|Homo sapiens protein ( Human mRNA for
liver pyruvate dehydrogenase (EC 1.2.4.1) E1' subunit.
).
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>X52709-1|CAA36933.1| 390|Homo sapiens protein ( Human mRNA for
brain pyruvate dehydrogenase (EC 1.2.4.1). ).
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>M27257-1|AAA60051.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>M24848-1|AAA36533.1| 390|Homo sapiens protein ( Human pyruvate
dehydrogenase alpha subunit mRNA, complete cds. ).
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>L13318-1|AAA60227.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit protein.
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>J03575-1|AAA60050.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>J03503-1|AAA60055.1| 414|Homo sapiens PDHA1 protein.
Length = 414
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 25 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 81
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 82 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 141
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 142 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 201
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 202 ALACKYNGKDEVCLTLYG 219
>D90084-1|BAA14121.1| 390|Homo sapiens pyruvate dehydrogenase alpha
subunit protein.
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>BC002406-1|AAH02406.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>AL732326-7|CAI41291.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>AK222988-1|BAD96708.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>AK222740-1|BAD96460.1| 390|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 variant protein.
Length = 390
Score = 214 bits (522), Expect = 3e-55
Identities = 100/198 (50%), Positives = 135/198 (68%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGV 711
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGI 177
Query: 712 AFAHKYRADGGVTFALYG 765
A A KY V LYG
Sbjct: 178 ALACKYNGKDEVCLTLYG 195
>EF590117-1|ABQ59099.1| 428|Homo sapiens mitochondrial PDHA1
protein.
Length = 428
Score = 209 bits (511), Expect = 7e-54
Identities = 94/163 (57%), Positives = 118/163 (72%)
Frame = +1
Query: 277 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 456
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 457 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGS 636
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGS
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGS 190
Query: 637 MHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYG 765
MH+Y +NFYGGNGIVGAQVPLGAG+A A KY V LYG
Sbjct: 191 MHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYG 233
>AL732326-6|CAI41290.1| 204|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 204
Score = 204 bits (499), Expect = 2e-52
Identities = 100/205 (48%), Positives = 135/205 (65%), Gaps = 7/205 (3%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQ-------EAVAVGMRAAMRD 510
ED LK Y + +RR+E + LYK+KIIRGFCHL GQ EA VG+ A +
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQFLLPLTQEACCVGLEAGINP 117
Query: 511 ADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQ 690
D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQ
Sbjct: 118 TDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQ 177
Query: 691 VPLGAGVAFAHKYRADGGVTFALYG 765
VPLGAG+A A KY V LYG
Sbjct: 178 VPLGAGIALACKYNGKDEVCLTLYG 202
>M86808-1|AAA60232.1| 388|Homo sapiens pyruvate dehydrogenase
complex protein.
Length = 388
Score = 199 bits (485), Expect = 1e-50
Identities = 90/170 (52%), Positives = 118/170 (69%)
Frame = +1
Query: 256 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 435
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 436 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 615
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 616 SRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYG 765
++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ + + LYG
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYG 193
>BC127638-1|AAI27639.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 199 bits (485), Expect = 1e-50
Identities = 90/170 (52%), Positives = 118/170 (69%)
Frame = +1
Query: 256 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 435
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 436 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 615
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 616 SRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYG 765
++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ + + LYG
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYG 193
>BC127637-1|AAI27638.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 199 bits (485), Expect = 1e-50
Identities = 90/170 (52%), Positives = 118/170 (69%)
Frame = +1
Query: 256 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 435
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 436 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 615
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 616 SRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYG 765
++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ + + LYG
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYG 193
>BC119657-1|AAI19658.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 199 bits (485), Expect = 1e-50
Identities = 90/170 (52%), Positives = 118/170 (69%)
Frame = +1
Query: 256 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 435
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 436 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 615
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 616 SRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYG 765
++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ + + LYG
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYG 193
>BC119656-1|AAI19657.1| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 199 bits (485), Expect = 1e-50
Identities = 90/170 (52%), Positives = 118/170 (69%)
Frame = +1
Query: 256 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 435
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 436 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 615
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 616 SRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYG 765
++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ + + LYG
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYG 193
>BC094760-1|AAH94760.1| 407|Homo sapiens PDHA2 protein protein.
Length = 407
Score = 199 bits (485), Expect = 1e-50
Identities = 90/170 (52%), Positives = 118/170 (69%)
Frame = +1
Query: 256 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 435
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 43 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 102
Query: 436 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 615
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 103 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 162
Query: 616 SRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYG 765
++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ + + LYG
Sbjct: 163 AKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYG 212
>BC030697-1|AAH30697.3| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 199 bits (485), Expect = 1e-50
Identities = 90/170 (52%), Positives = 118/170 (69%)
Frame = +1
Query: 256 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 435
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 436 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 615
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G+SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGLSVRSILAELTGRRGGC 143
Query: 616 SRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYG 765
++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ + + LYG
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYG 193
>BC066953-1|AAH66953.2| 388|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 2 protein.
Length = 388
Score = 198 bits (482), Expect = 2e-50
Identities = 90/170 (52%), Positives = 117/170 (68%)
Frame = +1
Query: 256 AKYSTKKEATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEK 435
A ++ +ATFEIK L+ L++GP + LT + LK Y + +RR+E + LYK+K
Sbjct: 24 ASRNSSNDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQK 83
Query: 436 IIRGFCHLYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGC 615
IRGFCHL GQEA VG+ A + +D VIT+YR HG Y G SV +L+ELTGRR GC
Sbjct: 84 FIRGFCHLCDGQEACCVGLEAGINPSDHVITSYRAHGVCYTRGPSVRSILAELTGRRGGC 143
Query: 616 SRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGVTFALYG 765
++GKGGSMH+Y +NFYGGNGIVGAQ PLGAG+A A KY+ + + LYG
Sbjct: 144 AKGKGGSMHMYTKNFYGGNGIVGAQGPLGAGIALACKYKGNDEICLTLYG 193
>AL732326-5|CAI41289.1| 180|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 180
Score = 188 bits (459), Expect = 1e-47
Identities = 87/174 (50%), Positives = 121/174 (69%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + ++ L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSRVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A + D +ITA
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITA 117
Query: 532 YRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQV 693
YR HG+T+ G+SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQV
Sbjct: 118 YRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQV 171
>AL732326-4|CAI41288.1| 205|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 205
Score = 176 bits (429), Expect = 6e-44
Identities = 77/135 (57%), Positives = 100/135 (74%)
Frame = +1
Query: 277 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 456
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 71 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 130
Query: 457 LYSGQEAVAVGMRAAMRDADSVITAYRCHGWTYLMGVSVLGVLSELTGRRTGCSRGKGGS 636
L GQEA VG+ A + D +ITAYR HG+T+ G+SV +L+ELTGR+ GC++GKGGS
Sbjct: 131 LCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGS 190
Query: 637 MHLYGRNFYGGNGIV 681
MH+Y +NFYGGNGIV
Sbjct: 191 MHMYAKNFYGGNGIV 205
>EF576990-1|ABQ58815.1| 261|Homo sapiens PDHA1 protein.
Length = 261
Score = 100 bits (239), Expect = 7e-21
Identities = 44/66 (66%), Positives = 52/66 (78%)
Frame = +1
Query: 568 SVLGVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLGAGVAFAHKYRADGGV 747
SV +L+ELTGR+ GC++GKGGSMH+Y +NFYGGNGIVGAQVPLGAG+A A KY V
Sbjct: 1 SVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEV 60
Query: 748 TFALYG 765
LYG
Sbjct: 61 CLTLYG 66
>L48690-1|AAB59581.1| 390|Homo sapiens pyruvate dehydrogenase
E1-alpha subunit precursor protein.
Length = 390
Score = 98.7 bits (235), Expect = 2e-20
Identities = 66/201 (32%), Positives = 95/201 (47%), Gaps = 3/201 (1%)
Frame = +1
Query: 172 MSKLIPSAAKFLAGNTITKVTAPVVATNAKYSTKKEATFEIKPYKLHKLDQGPATSATLT 351
M K++ + + L+G + + +VA+ + +ATFEIK LH+L++GP + LT
Sbjct: 1 MRKMLAAVSPVLSGASQKPASRVLVASR---NFANDATFEIKKCDLHRLEEGPPVTTVLT 57
Query: 352 SEDALKLYEQLTILRRIETASGNLYKEKIIRGFCHLYSGQEAVAVGMRAAMRDADSVITA 531
ED LK Y + +RR+E + LYK+KIIRGFCHL GQEA VG+ A I++
Sbjct: 58 REDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLERA--STPQTISS 115
Query: 532 YRCHGWTYLMGVSVL---GVLSELTGRRTGCSRGKGGSMHLYGRNFYGGNGIVGAQVPLG 702
+ G T L+ L + +GK R G + P
Sbjct: 116 -QPTGLTALLSPGAFPSEKFSQSLQDEKEVVLKGKEDRCTCMPRTSTGAMASWERRCPWA 174
Query: 703 AGVAFAHKYRADGGVTFALYG 765
AG+A A KY V LYG
Sbjct: 175 AGIALACKYNGKDEVCLTLYG 195
>AL732326-3|CAI41287.1| 121|Homo sapiens pyruvate dehydrogenase
(lipoamide) alpha 1 protein.
Length = 121
Score = 76.6 bits (180), Expect = 9e-14
Identities = 33/61 (54%), Positives = 43/61 (70%)
Frame = +1
Query: 277 EATFEIKPYKLHKLDQGPATSATLTSEDALKLYEQLTILRRIETASGNLYKEKIIRGFCH 456
+ATFEIK LH+L++GP + LT ED LK Y + +RR+E + LYK+KIIRGFCH
Sbjct: 61 DATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCH 120
Query: 457 L 459
L
Sbjct: 121 L 121
>BC150265-1|AAI50266.1| 1481|Homo sapiens CRKRS protein protein.
Length = 1481
Score = 40.3 bits (90), Expect = 0.007
Identities = 26/63 (41%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAP-TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPST 570
TPP + + P P T P T PLPP P +PPLP QP V + ST ST
Sbjct: 525 TPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASST-ST 583
Query: 569 LTP 561
L P
Sbjct: 584 LPP 586
>AF227198-1|AAF36401.1| 1490|Homo sapiens CrkRS protein.
Length = 1490
Score = 40.3 bits (90), Expect = 0.007
Identities = 26/63 (41%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAP-TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPST 570
TPP + + P P T P T PLPP P +PPLP QP V + ST ST
Sbjct: 525 TPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASST-ST 583
Query: 569 LTP 561
L P
Sbjct: 584 LPP 586
>AB020711-1|BAA74927.2| 1535|Homo sapiens KIAA0904 protein protein.
Length = 1535
Score = 40.3 bits (90), Expect = 0.007
Identities = 26/63 (41%), Positives = 30/63 (47%), Gaps = 1/63 (1%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAP-TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPST 570
TPP + + P P T P T PLPP P +PPLP QP V + ST ST
Sbjct: 579 TPPPLPTIASPPPPLPTTTPPPQTPPLPPLPPIPALPQQPPLPPSQPAFSQVPASST-ST 637
Query: 569 LTP 561
L P
Sbjct: 638 LPP 640
>AM746210-1|CAN88919.1| 302|Homo sapiens PDHA1/LOC79064 protein
protein.
Length = 302
Score = 34.7 bits (76), Expect = 0.37
Identities = 16/27 (59%), Positives = 17/27 (62%)
Frame = +1
Query: 685 AQVPLGAGVAFAHKYRADGGVTFALYG 765
AQVPLGAG+A A KY V LYG
Sbjct: 81 AQVPLGAGIALACKYNGKDEVCLTLYG 107
>BC052955-1|AAH52955.1| 505|Homo sapiens Wiskott-Aldrich
syndrome-like protein.
Length = 505
Score = 34.3 bits (75), Expect = 0.48
Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Frame = -2
Query: 764 PYRANVTPPSARYLWAKATPAPNGTCAPTI-PLPP*KLRPYKCMEPPLP-REQPVLRPVS 591
P+ + PP AR + P P + APT P PP RP + PP P R P P
Sbjct: 294 PHNSGPPPPPAR---GRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPAL 350
Query: 590 SESTPSTLTP 561
S PS P
Sbjct: 351 PSSAPSGPPP 360
>AC006333-1|AAQ96857.1| 505|Homo sapiens unknown protein.
Length = 505
Score = 34.3 bits (75), Expect = 0.48
Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Frame = -2
Query: 764 PYRANVTPPSARYLWAKATPAPNGTCAPTI-PLPP*KLRPYKCMEPPLP-REQPVLRPVS 591
P+ + PP AR + P P + APT P PP RP + PP P R P P
Sbjct: 294 PHNSGPPPPPAR---GRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPAL 350
Query: 590 SESTPSTLTP 561
S PS P
Sbjct: 351 PSSAPSGPPP 360
>AM295156-1|CAL26602.1| 505|Homo sapiens WASL protein protein.
Length = 505
Score = 33.9 bits (74), Expect = 0.64
Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Frame = -2
Query: 764 PYRANVTPPSARYLWAKATPAPNGTCAPTI-PLPP*KLRPYKCMEPPLP-REQPVLRPVS 591
P+ + PP AR + P P + APT P PP RP + PP P R P P
Sbjct: 294 PHNSGPPPPPAR---GRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPAL 350
Query: 590 SESTPSTLTP 561
S PS P
Sbjct: 351 LSSAPSGPPP 360
>D88460-1|BAA20128.1| 505|Homo sapiens N-WASP protein.
Length = 505
Score = 32.3 bits (70), Expect = 2.0
Identities = 25/70 (35%), Positives = 30/70 (42%), Gaps = 2/70 (2%)
Frame = -2
Query: 764 PYRANVTPPSARYLWAKATPAPNGTCAPTI-PLPP*KLRPYKCMEPPLP-REQPVLRPVS 591
P+ + PP AR + P P + APT P PP RP + PP P R P P
Sbjct: 294 PHSSGPPPPPAR---GRGAPPPPPSRAPTAAPPPPPPSRPSVEVPPPPPNRMYPPPPPAL 350
Query: 590 SESTPSTLTP 561
S PS P
Sbjct: 351 PSSAPSGPPP 360
>BC039878-1|AAH39878.1| 825|Homo sapiens chromosome 14 open reading
frame 155 protein.
Length = 825
Score = 31.9 bits (69), Expect = 2.6
Identities = 17/65 (26%), Positives = 26/65 (40%)
Frame = -2
Query: 755 ANVTPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTP 576
A V PP A A+ P P + PP + P + PP ++P +E P
Sbjct: 608 AEVQPPPAEEAPAEVQPPPAEEAPAEVQPPPAEETPAEVQPPPAEEAPAEVQPPPAEEAP 667
Query: 575 STLTP 561
+ + P
Sbjct: 668 AEVQP 672
>AJ420811-1|CAD12730.1| 344|Homo sapiens ADAMTS-13 protein,
truncated variant protein.
Length = 344
Score = 31.9 bits (69), Expect = 2.6
Identities = 18/44 (40%), Positives = 22/44 (50%)
Frame = -2
Query: 707 PAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTP 576
PAP G P P+P K ++ LP P+LRP SS TP
Sbjct: 303 PAPGGGRGPRTPVPTHKRPRFQT----LPSSCPLLRPASSRCTP 342
>Y13440-1|CAA73851.1| 582|Homo sapiens Rox protein.
Length = 582
Score = 31.5 bits (68), Expect = 3.4
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Frame = -2
Query: 764 PYRANVTPPSARYLWAKATPAPNGTCAPTIPLPP*KL--RPYKCMEPPLPREQP 609
P R V P+ +KAT PNG+ P PLP L P+ ++P L +QP
Sbjct: 138 PSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQP 191
>Y11354-1|CAA72189.1| 1083|Homo sapiens subunit of RNA polymerase II
transcription factor protein.
Length = 1083
Score = 31.5 bits (68), Expect = 3.4
Identities = 21/62 (33%), Positives = 26/62 (41%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTL 567
TPP ++ A A PAP AP+ P P P PP P + RP + P T
Sbjct: 238 TPP---FVGAAAPPAP---AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTA 291
Query: 566 TP 561
P
Sbjct: 292 AP 293
>X96401-1|CAA65265.1| 582|Homo sapiens ROX protein protein.
Length = 582
Score = 31.5 bits (68), Expect = 3.4
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Frame = -2
Query: 764 PYRANVTPPSARYLWAKATPAPNGTCAPTIPLPP*KL--RPYKCMEPPLPREQP 609
P R V P+ +KAT PNG+ P PLP L P+ ++P L +QP
Sbjct: 138 PSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQP 191
>BC117563-1|AAI17564.1| 582|Homo sapiens MAX binding protein
protein.
Length = 582
Score = 31.5 bits (68), Expect = 3.4
Identities = 20/54 (37%), Positives = 27/54 (50%), Gaps = 2/54 (3%)
Frame = -2
Query: 764 PYRANVTPPSARYLWAKATPAPNGTCAPTIPLPP*KL--RPYKCMEPPLPREQP 609
P R V P+ +KAT PNG+ P PLP L P+ ++P L +QP
Sbjct: 138 PSRPQVPTPAPLLPDSKATIPPNGSPKPLQPLPTPVLTIAPHPGVQPQLAPQQP 191
>AY623115-1|AAT38111.1| 1085|Homo sapiens TAF4 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 135kD
protein.
Length = 1085
Score = 31.5 bits (68), Expect = 3.4
Identities = 21/62 (33%), Positives = 26/62 (41%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTL 567
TPP ++ A A PAP AP+ P P P PP P + RP + P T
Sbjct: 240 TPP---FVGAAAPPAP---AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTA 293
Query: 566 TP 561
P
Sbjct: 294 AP 295
>AL137077-2|CAI11045.1| 1085|Homo sapiens TAF4 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 135kD
protein.
Length = 1085
Score = 31.5 bits (68), Expect = 3.4
Identities = 21/62 (33%), Positives = 26/62 (41%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTL 567
TPP ++ A A PAP AP+ P P P PP P + RP + P T
Sbjct: 240 TPP---FVGAAAPPAP---AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTA 293
Query: 566 TP 561
P
Sbjct: 294 AP 295
>AL109911-2|CAI19182.1| 1085|Homo sapiens TAF4 RNA polymerase II,
TATA box binding protein (TBP)-associated factor, 135kD
protein.
Length = 1085
Score = 31.5 bits (68), Expect = 3.4
Identities = 21/62 (33%), Positives = 26/62 (41%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTL 567
TPP ++ A A PAP AP+ P P P PP P + RP + P T
Sbjct: 240 TPP---FVGAAAPPAP---AAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTA 293
Query: 566 TP 561
P
Sbjct: 294 AP 295
>AK130326-1|BAC85327.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ26816 fis, clone PRS06437. ).
Length = 508
Score = 31.5 bits (68), Expect = 3.4
Identities = 22/60 (36%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Frame = -2
Query: 668 PP*KLRPYKCMEP-PLPREQPVLRPVSSESTPSTLTPMR*VHP*QRYAVITESASRIAAL 492
PP KL+P +P P + QP L P ++ P T TP HP Q + + E S + AL
Sbjct: 402 PPPKLQPQPQPQPQPQSQPQPQLPP-QPQTQPQTPTPAP-QHPQQTWPPVNEGESAMRAL 459
>AL611964-2|CAH73872.1| 495|Homo sapiens REST corepressor 3
protein.
Length = 495
Score = 31.1 bits (67), Expect = 4.5
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAPTIPL-----PP*KLRPYKCMEPPLPREQPVLR 600
TP + R L + PAP+ T PT P+ PP LRP P L R+ P L+
Sbjct: 384 TPQAPRTL-GPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQ 436
>AL590101-2|CAH72433.1| 495|Homo sapiens REST corepressor 3
protein.
Length = 495
Score = 31.1 bits (67), Expect = 4.5
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAPTIPL-----PP*KLRPYKCMEPPLPREQPVLR 600
TP + R L + PAP+ T PT P+ PP LRP P L R+ P L+
Sbjct: 384 TPQAPRTL-GPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQ 436
>AK001738-1|BAA91872.1| 495|Homo sapiens protein ( Homo sapiens
cDNA FLJ10876 fis, clone NT2RP4001838, weakly similar to
Homo sapiens CoREST protein mRNA. ).
Length = 495
Score = 31.1 bits (67), Expect = 4.5
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAPTIPL-----PP*KLRPYKCMEPPLPREQPVLR 600
TP + R L + PAP+ T PT P+ PP LRP P L R+ P L+
Sbjct: 384 TPQAPRTL-GPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQ 436
>AB037764-1|BAA92581.1| 520|Homo sapiens KIAA1343 protein protein.
Length = 520
Score = 31.1 bits (67), Expect = 4.5
Identities = 21/54 (38%), Positives = 27/54 (50%), Gaps = 5/54 (9%)
Frame = -2
Query: 746 TPPSARYLWAKATPAPNGTCAPTIPL-----PP*KLRPYKCMEPPLPREQPVLR 600
TP + R L + PAP+ T PT P+ PP LRP P L R+ P L+
Sbjct: 409 TPQAPRTL-GPSPPAPSSTPTPTAPIATLNQPPPLLRPTLPAAPALHRQPPPLQ 461
>AK025837-1|BAB15254.1| 616|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22184 fis, clone HRC00983. ).
Length = 616
Score = 30.7 bits (66), Expect = 6.0
Identities = 20/68 (29%), Positives = 28/68 (41%)
Frame = -2
Query: 764 PYRANVTPPSARYLWAKATPAPNGTCAPTIPLPP*KLRPYKCMEPPLPREQPVLRPVSSE 585
P +A +PP++ L ATP+P A + L P P P PVS
Sbjct: 121 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 180
Query: 584 STPSTLTP 561
+TP + P
Sbjct: 181 ATPPSQAP 188
>BC131733-1|AAI31734.1| 1509|Homo sapiens ADAMTS12 protein protein.
Length = 1509
Score = 30.3 bits (65), Expect = 7.9
Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 1/59 (1%)
Frame = -2
Query: 743 PPSARYLWAKATPAPNGTCAPTI-PLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPST 570
P S R L NG PT+ P+PP RP P P P S +P+T
Sbjct: 912 PSSRRVLKPNKGTISNGKNPPTLKPVPPPTSRPRMLTTPTGPESMSTSTPAISSPSPTT 970
>AM231061-1|CAJ76912.1| 1960|Homo sapiens obscurin isoform B protein.
Length = 1960
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 3/61 (4%)
Frame = -2
Query: 734 ARYLWAKATPAPNGTCAP---TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLT 564
A + K AP C+P P PP P C E PL P L + P+ +
Sbjct: 1024 APFCHPKQGSAPQEGCSPHPAVAPCPPGSFPPGSCKEAPLVPSSPFLGQPQAPPAPAKAS 1083
Query: 563 P 561
P
Sbjct: 1084 P 1084
>AL670729-4|CAH71670.2| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 3/61 (4%)
Frame = -2
Query: 734 ARYLWAKATPAPNGTCAP---TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLT 564
A + K AP C+P P PP P C E PL P L + P+ +
Sbjct: 1648 APFCHPKQGSAPQEGCSPHPAVAPCPPGSFPPGSCKEAPLVPSSPFLGQPQAPPAPAKAS 1707
Query: 563 P 561
P
Sbjct: 1708 P 1708
>AL353593-4|CAM27610.1| 2582|Homo sapiens obscurin, cytoskeletal
calmodulin and titin-interacting RhoGEF protein.
Length = 2582
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 3/61 (4%)
Frame = -2
Query: 734 ARYLWAKATPAPNGTCAP---TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLT 564
A + K AP C+P P PP P C E PL P L + P+ +
Sbjct: 1648 APFCHPKQGSAPQEGCSPHPAVAPCPPGSFPPGSCKEAPLVPSSPFLGQPQAPPAPAKAS 1707
Query: 563 P 561
P
Sbjct: 1708 P 1708
>AJ250725-1|CAC20419.1| 1593|Homo sapiens a disintegrin-like and
metalloprotease (reprolysin type) with thrombospondin ty
protein.
Length = 1593
Score = 30.3 bits (65), Expect = 7.9
Identities = 19/59 (32%), Positives = 23/59 (38%), Gaps = 1/59 (1%)
Frame = -2
Query: 743 PPSARYLWAKATPAPNGTCAPTI-PLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPST 570
P S R L NG PT+ P+PP RP P P P S +P+T
Sbjct: 996 PSSRRVLKPNKGTISNGKNPPTLKPVPPPTSRPRMLTTPTGPESMSTSTPAISSPSPTT 1054
>AB058759-1|BAB47485.1| 1134|Homo sapiens KIAA1856 protein protein.
Length = 1134
Score = 30.3 bits (65), Expect = 7.9
Identities = 20/53 (37%), Positives = 22/53 (41%), Gaps = 1/53 (1%)
Frame = -2
Query: 764 PYRANVTPPSARYLWAKATPAPNGTCAPT-IPLPP*KLRPYKCMEPPLPREQP 609
P RA P AR P P+ P +P PP LR PPLPR P
Sbjct: 942 PPRAPALPSEARAPPPPPPPPPHPPLPPPPLPPPPLPLRLPPLPPPPLPRPHP 994
>AB046859-1|BAB13465.2| 2584|Homo sapiens KIAA1639 protein protein.
Length = 2584
Score = 30.3 bits (65), Expect = 7.9
Identities = 18/61 (29%), Positives = 23/61 (37%), Gaps = 3/61 (4%)
Frame = -2
Query: 734 ARYLWAKATPAPNGTCAP---TIPLPP*KLRPYKCMEPPLPREQPVLRPVSSESTPSTLT 564
A + K AP C+P P PP P C E PL P L + P+ +
Sbjct: 1648 APFCHPKQGSAPQEGCSPHPAVAPCPPGSFPPGSCKEAPLVPSSPFLGQPQAPPAPAKAS 1707
Query: 563 P 561
P
Sbjct: 1708 P 1708
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 112,906,859
Number of Sequences: 237096
Number of extensions: 2486152
Number of successful extensions: 8708
Number of sequences better than 10.0: 57
Number of HSP's better than 10.0 without gapping: 7814
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 8656
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9199990470
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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