Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV15a19f
(628 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 212 8e-55
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 212 8e-55
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 212 8e-55
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 212 8e-55
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 194 2e-49
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 186 4e-47
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 186 4e-47
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 186 4e-47
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 184 2e-46
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 184 2e-46
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 184 2e-46
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 184 2e-46
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 184 2e-46
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 184 2e-46
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 184 2e-46
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 184 2e-46
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 184 2e-46
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 184 2e-46
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 184 3e-46
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 99 1e-20
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 99 1e-20
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 98 2e-20
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 83 6e-16
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 212 bits (518), Expect = 8e-55
Identities = 88/176 (50%), Positives = 123/176 (69%)
Frame = +3
Query: 96 YTKFPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRY 275
Y +FP+GF + A+A++QIEGAW GK ++WD +HT P + + GDVACDSYH+
Sbjct: 1374 YGRFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKI 1432
Query: 276 LEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLF 455
ED+ L LGV YRFS+SWSRILP G + ++N G+ YY L+D L +I+P VT++
Sbjct: 1433 AEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIY 1492
Query: 456 HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
HWDLPQ+LQD+GGW N +V F++Y+DV ++ GDK+K WIT+NEP+ + YG
Sbjct: 1493 HWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYG 1548
Score = 208 bits (509), Expect = 9e-54
Identities = 86/173 (49%), Positives = 117/173 (67%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
F D F +GV+++++QIEGAW+ GK ++WD THT + D GD+ACDSYH+ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWD 464
+ L L V YRFS+SWSRI PTG + +N G+ YYN L++ L NI P+VTLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 465 LPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
LPQ+LQD+GGW N ++D F Y+D C++ FGD++K W+T NEP + YG
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYG 1075
Score = 173 bits (421), Expect = 4e-43
Identities = 77/174 (44%), Positives = 105/174 (60%), Gaps = 1/174 (0%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADG-TNGDVACDSYHRYLE 281
FP+GF +G +T + +EG W G+ ++WD RP +G +VA DSYH+
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYHKVAS 438
Query: 282 DVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHW 461
DV L L Y+FS+SWSRI P G + G+ YYN L+D L + IEP+ TLFHW
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHW 498
Query: 462 DLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
DLPQ+LQD GGW N +VD F DY+ C+ FGD++K W+T +EP+ + YG
Sbjct: 499 DLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYG 552
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/102 (29%), Positives = 50/102 (49%)
Frame = +3
Query: 309 VDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWDLPQSLQDL 488
+ Y+ LSW+++LP G + + + ++ Y LL AL ++P+V L H LP S
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR- 142
Query: 489 GGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCED 614
D F DY+ + FGD + W T ++ EV ++
Sbjct: 143 ---RTEAFADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKE 181
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 212 bits (518), Expect = 8e-55
Identities = 88/176 (50%), Positives = 123/176 (69%)
Frame = +3
Query: 96 YTKFPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRY 275
Y +FP+GF + A+A++QIEGAW GK ++WD +HT P + + GDVACDSYH+
Sbjct: 1374 YGRFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKI 1432
Query: 276 LEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLF 455
ED+ L LGV YRFS+SWSRILP G + ++N G+ YY L+D L +I+P VT++
Sbjct: 1433 AEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIY 1492
Query: 456 HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
HWDLPQ+LQD+GGW N +V F++Y+DV ++ GDK+K WIT+NEP+ + YG
Sbjct: 1493 HWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYG 1548
Score = 208 bits (509), Expect = 9e-54
Identities = 86/173 (49%), Positives = 117/173 (67%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
F D F +GV+++++QIEGAW+ GK ++WD THT + D GD+ACDSYH+ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWD 464
+ L L V YRFS+SWSRI PTG + +N G+ YYN L++ L NI P+VTLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 465 LPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
LPQ+LQD+GGW N ++D F Y+D C++ FGD++K W+T NEP + YG
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYG 1075
Score = 173 bits (421), Expect = 4e-43
Identities = 77/174 (44%), Positives = 105/174 (60%), Gaps = 1/174 (0%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADG-TNGDVACDSYHRYLE 281
FP+GF +G +T + +EG W G+ ++WD RP +G +VA DSYH+
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYHKVAS 438
Query: 282 DVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHW 461
DV L L Y+FS+SWSRI P G + G+ YYN L+D L + IEP+ TLFHW
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHW 498
Query: 462 DLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
DLPQ+LQD GGW N +VD F DY+ C+ FGD++K W+T +EP+ + YG
Sbjct: 499 DLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYG 552
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/102 (29%), Positives = 50/102 (49%)
Frame = +3
Query: 309 VDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWDLPQSLQDL 488
+ Y+ LSW+++LP G + + + ++ Y LL AL ++P+V L H LP S
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR- 142
Query: 489 GGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCED 614
D F DY+ + FGD + W T ++ EV ++
Sbjct: 143 ---RTEAFADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKE 181
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 212 bits (518), Expect = 8e-55
Identities = 88/176 (50%), Positives = 123/176 (69%)
Frame = +3
Query: 96 YTKFPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRY 275
Y +FP+GF + A+A++QIEGAW GK ++WD +HT P + + GDVACDSYH+
Sbjct: 806 YGRFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKI 864
Query: 276 LEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLF 455
ED+ L LGV YRFS+SWSRILP G + ++N G+ YY L+D L +I+P VT++
Sbjct: 865 AEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIY 924
Query: 456 HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
HWDLPQ+LQD+GGW N +V F++Y+DV ++ GDK+K WIT+NEP+ + YG
Sbjct: 925 HWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYG 980
Score = 208 bits (509), Expect = 9e-54
Identities = 86/173 (49%), Positives = 117/173 (67%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
F D F +GV+++++QIEGAW+ GK ++WD THT + D GD+ACDSYH+ D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWD 464
+ L L V YRFS+SWSRI PTG + +N G+ YYN L++ L NI P+VTLFHWD
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 454
Query: 465 LPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
LPQ+LQD+GGW N ++D F Y+D C++ FGD++K W+T NEP + YG
Sbjct: 455 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYG 507
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 212 bits (518), Expect = 8e-55
Identities = 88/176 (50%), Positives = 123/176 (69%)
Frame = +3
Query: 96 YTKFPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRY 275
Y +FP+GF + A+A++QIEGAW GK ++WD +HT P + + GDVACDSYH+
Sbjct: 1374 YGRFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKI 1432
Query: 276 LEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLF 455
ED+ L LGV YRFS+SWSRILP G + ++N G+ YY L+D L +I+P VT++
Sbjct: 1433 AEDLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIY 1492
Query: 456 HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
HWDLPQ+LQD+GGW N +V F++Y+DV ++ GDK+K WIT+NEP+ + YG
Sbjct: 1493 HWDLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYG 1548
Score = 208 bits (509), Expect = 9e-54
Identities = 86/173 (49%), Positives = 117/173 (67%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
F D F +GV+++++QIEGAW+ GK ++WD THT + D GD+ACDSYH+ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWD 464
+ L L V YRFS+SWSRI PTG + +N G+ YYN L++ L NI P+VTLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 465 LPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
LPQ+LQD+GGW N ++D F Y+D C++ FGD++K W+T NEP + YG
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYG 1075
Score = 173 bits (421), Expect = 4e-43
Identities = 77/174 (44%), Positives = 105/174 (60%), Gaps = 1/174 (0%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADG-TNGDVACDSYHRYLE 281
FP+GF +G +T + +EG W G+ ++WD RP +G +VA DSYH+
Sbjct: 382 FPEGFLWGASTGAFNVEGGWAEGGRGVSIWDP---RRPLNTTEGQATLEVASDSYHKVAS 438
Query: 282 DVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHW 461
DV L L Y+FS+SWSRI P G + G+ YYN L+D L + IEP+ TLFHW
Sbjct: 439 DVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATLFHW 498
Query: 462 DLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAYG 623
DLPQ+LQD GGW N +VD F DY+ C+ FGD++K W+T +EP+ + YG
Sbjct: 499 DLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYG 552
Score = 60.9 bits (141), Expect = 4e-09
Identities = 30/102 (29%), Positives = 50/102 (49%)
Frame = +3
Query: 309 VDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWDLPQSLQDL 488
+ Y+ LSW+++LP G + + + ++ Y LL AL ++P+V L H LP S
Sbjct: 84 ITHYKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLR- 142
Query: 489 GGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCED 614
D F DY+ + FGD + W T ++ EV ++
Sbjct: 143 ---RTEAFADLFADYATFAFHSFGDLVGIWFTFSDLEEVIKE 181
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 194 bits (474), Expect = 2e-49
Identities = 85/177 (48%), Positives = 117/177 (66%), Gaps = 2/177 (1%)
Frame = +3
Query: 96 YTKFPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRY 275
Y FP GF++GV ++++Q EGAW+ GK ++WD TH+ + DVACD Y++
Sbjct: 34 YGTFPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKV 93
Query: 276 LEDVEELTYLGVDFYRFSLSWSRILPTGF-SDHVNPDGIRYYNALLDALAEKNIEPLVTL 452
ED+ L L V+ YRFSLSW R+LPTG ++ VN GI +Y+ L+DAL NI P+VTL
Sbjct: 94 QEDIILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTL 153
Query: 453 FHWDLPQSLQ-DLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPYEVCEDAY 620
HWDLPQ LQ GGW N M +YFRDY+++C+ FGD++K WIT ++P + E Y
Sbjct: 154 HHWDLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGY 210
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 186 bits (454), Expect = 4e-47
Identities = 84/199 (42%), Positives = 120/199 (60%), Gaps = 1/199 (0%)
Frame = +3
Query: 30 DDTMAWLTTLSILAVCHTGLAAYTKFPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTH 209
D W + V + L Y FP F +G+ T + Q+EG+W GK ++WD H
Sbjct: 56 DGRAIWSKNPNFTPVNESQLFLYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIH 115
Query: 210 TRPEMIADGTNGDVACDSYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGI 389
T + ++ TNG + DSY +D+ L ++GV FY+FS+SW R+ P G N G+
Sbjct: 116 THLKNVSS-TNG--SSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGL 172
Query: 390 RYYNALLDALAEKNIEPLVTLFHWDLPQSLQD-LGGWTNSKMVDYFRDYSDVCYREFGDK 566
+YY+ LLDAL +NIEP+VTL+HWDLP +LQ+ GGW N ++D F DY+ C++ FGD+
Sbjct: 173 QYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDR 232
Query: 567 IKSWITINEPYEVCEDAYG 623
+K WITI+ PY V YG
Sbjct: 233 VKYWITIHNPYLVAWHGYG 251
Score = 92.7 bits (220), Expect = 1e-18
Identities = 57/177 (32%), Positives = 86/177 (48%), Gaps = 12/177 (6%)
Frame = +3
Query: 102 KFPDGFTFGVATA---SHQIEGAWNVSGKSENVWD----RLTHTRPEMIADGTNGDVACD 260
+FP F++GV + + + S VW+ RL H R E + T C
Sbjct: 520 QFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVRLKTR-PAQCT 577
Query: 261 SYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEP 440
+ + +E L + V YRF+L W+ +LPTG VN +RYY ++ + I
Sbjct: 578 DFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISA 637
Query: 441 LVTLF-----HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEP 596
+VTL+ H LP+ L GW N + F+ Y+ +C++E GD +K WITINEP
Sbjct: 638 MVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEP 694
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 186 bits (454), Expect = 4e-47
Identities = 84/199 (42%), Positives = 120/199 (60%), Gaps = 1/199 (0%)
Frame = +3
Query: 30 DDTMAWLTTLSILAVCHTGLAAYTKFPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTH 209
D W + V + L Y FP F +G+ T + Q+EG+W GK ++WD H
Sbjct: 56 DGRAIWSKNPNFTPVNESQLFLYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIH 115
Query: 210 TRPEMIADGTNGDVACDSYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGI 389
T + ++ TNG + DSY +D+ L ++GV FY+FS+SW R+ P G N G+
Sbjct: 116 THLKNVSS-TNG--SSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGL 172
Query: 390 RYYNALLDALAEKNIEPLVTLFHWDLPQSLQD-LGGWTNSKMVDYFRDYSDVCYREFGDK 566
+YY+ LLDAL +NIEP+VTL+HWDLP +LQ+ GGW N ++D F DY+ C++ FGD+
Sbjct: 173 QYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDR 232
Query: 567 IKSWITINEPYEVCEDAYG 623
+K WITI+ PY V YG
Sbjct: 233 VKYWITIHNPYLVAWHGYG 251
Score = 92.7 bits (220), Expect = 1e-18
Identities = 57/177 (32%), Positives = 86/177 (48%), Gaps = 12/177 (6%)
Frame = +3
Query: 102 KFPDGFTFGVATA---SHQIEGAWNVSGKSENVWD----RLTHTRPEMIADGTNGDVACD 260
+FP F++GV + + + S VW+ RL H R E + T C
Sbjct: 520 QFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVRLKTR-PAQCT 577
Query: 261 SYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEP 440
+ + +E L + V YRF+L W+ +LPTG VN +RYY ++ + I
Sbjct: 578 DFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISA 637
Query: 441 LVTLF-----HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEP 596
+VTL+ H LP+ L GW N + F+ Y+ +C++E GD +K WITINEP
Sbjct: 638 MVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEP 694
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 186 bits (454), Expect = 4e-47
Identities = 84/199 (42%), Positives = 120/199 (60%), Gaps = 1/199 (0%)
Frame = +3
Query: 30 DDTMAWLTTLSILAVCHTGLAAYTKFPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTH 209
D W + V + L Y FP F +G+ T + Q+EG+W GK ++WD H
Sbjct: 56 DGRAIWSKNPNFTPVNESQLFLYDTFPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIH 115
Query: 210 TRPEMIADGTNGDVACDSYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGI 389
T + ++ TNG + DSY +D+ L ++GV FY+FS+SW R+ P G N G+
Sbjct: 116 THLKNVSS-TNG--SSDSYIFLEKDLSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGL 172
Query: 390 RYYNALLDALAEKNIEPLVTLFHWDLPQSLQD-LGGWTNSKMVDYFRDYSDVCYREFGDK 566
+YY+ LLDAL +NIEP+VTL+HWDLP +LQ+ GGW N ++D F DY+ C++ FGD+
Sbjct: 173 QYYSTLLDALVLRNIEPIVTLYHWDLPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDR 232
Query: 567 IKSWITINEPYEVCEDAYG 623
+K WITI+ PY V YG
Sbjct: 233 VKYWITIHNPYLVAWHGYG 251
Score = 92.7 bits (220), Expect = 1e-18
Identities = 57/177 (32%), Positives = 86/177 (48%), Gaps = 12/177 (6%)
Frame = +3
Query: 102 KFPDGFTFGVATA---SHQIEGAWNVSGKSENVWD----RLTHTRPEMIADGTNGDVACD 260
+FP F++GV + + + S VW+ RL H R E + T C
Sbjct: 520 QFPCDFSWGVTESVLKPESVASSPQFSDPHLYVWNATGNRLLH-RVEGVRLKTR-PAQCT 577
Query: 261 SYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEP 440
+ + +E L + V YRF+L W+ +LPTG VN +RYY ++ + I
Sbjct: 578 DFVNIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISA 637
Query: 441 LVTLF-----HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEP 596
+VTL+ H LP+ L GW N + F+ Y+ +C++E GD +K WITINEP
Sbjct: 638 MVTLYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEP 694
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 184 bits (448), Expect = 2e-46
Identities = 86/188 (45%), Positives = 113/188 (60%), Gaps = 16/188 (8%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTN-------------- 242
FPDGF + V +A++Q EG W GK ++WD TH D N
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 243 -GDVACDSYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDAL 419
GDVA DSY+ D E L LGV YRFS+SW+R+LP G + N +G+RYY LL+ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 420 AEKNIEPLVTLFHWDLPQSLQD-LGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEP 596
E ++P+VTL+HWDLPQ LQD GGW N + D+FRDY+++C+R FG ++K WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 597 YEVCEDAY 620
Y V Y
Sbjct: 241 YVVAWHGY 248
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 184 bits (448), Expect = 2e-46
Identities = 77/163 (47%), Positives = 108/163 (66%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
FP GF + ATA++Q+EG W+ GK VWD TH E + GDVAC SY + ED
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWD 464
++ + LG+ YRFSLSWSR+LP G + +N GI YYN ++D L + + P+VTL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 465 LPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINE 593
LPQ+L+D GGW + +++ F Y+ C+ FGD++K WITINE
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 184 bits (448), Expect = 2e-46
Identities = 86/188 (45%), Positives = 113/188 (60%), Gaps = 16/188 (8%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTN-------------- 242
FPDGF + V +A++Q EG W GK ++WD TH D N
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 243 -GDVACDSYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDAL 419
GDVA DSY+ D E L LGV YRFS+SW+R+LP G + N +G+RYY LL+ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 420 AEKNIEPLVTLFHWDLPQSLQD-LGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEP 596
E ++P+VTL+HWDLPQ LQD GGW N + D+FRDY+++C+R FG ++K WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 597 YEVCEDAY 620
Y V Y
Sbjct: 241 YVVAWHGY 248
Score = 83.4 bits (197), Expect = 6e-16
Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 9/174 (5%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWN-VSGKSENVWDRLTHTRPEMIADGT---NGDVACDSYHR 272
FP F +GV Q++ + + + +WD + H++ + DG C +
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD-VHHSKRLIKVDGVVTKKRKSYCVDFAA 577
Query: 273 YLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTL 452
+ L + V +RFSL W+ ILP G VN ++YY + L NI P+V L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 453 F-----HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPY 599
+ + LP+ L G W N F +Y+ +C++E G +K WIT+NEPY
Sbjct: 638 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPY 691
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 184 bits (448), Expect = 2e-46
Identities = 77/163 (47%), Positives = 108/163 (66%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
FP GF + ATA++Q+EG W+ GK VWD TH E + GDVAC SY + ED
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWD 464
++ + LG+ YRFSLSWSR+LP G + +N GI YYN ++D L + + P+VTL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 465 LPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINE 593
LPQ+L+D GGW + +++ F Y+ C+ FGD++K WITINE
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 184 bits (448), Expect = 2e-46
Identities = 77/163 (47%), Positives = 108/163 (66%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
FP GF + ATA++Q+EG W+ GK VWD TH E + GDVAC SY + ED
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWD 464
++ + LG+ YRFSLSWSR+LP G + +N GI YYN ++D L + + P+VTL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 465 LPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINE 593
LPQ+L+D GGW + +++ F Y+ C+ FGD++K WITINE
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 184 bits (448), Expect = 2e-46
Identities = 77/163 (47%), Positives = 108/163 (66%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
FP GF + ATA++Q+EG W+ GK VWD TH E + GDVAC SY + ED
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWD 464
++ + LG+ YRFSLSWSR+LP G + +N GI YYN ++D L + + P+VTL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 465 LPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINE 593
LPQ+L+D GGW + +++ F Y+ C+ FGD++K WITINE
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 184 bits (448), Expect = 2e-46
Identities = 77/163 (47%), Positives = 108/163 (66%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
FP GF + ATA++Q+EG W+ GK VWD TH E + GDVAC SY + ED
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWD 464
++ + LG+ YRFSLSWSR+LP G + +N GI YYN ++D L + + P+VTL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 465 LPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINE 593
LPQ+L+D GGW + +++ F Y+ C+ FGD++K WITINE
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 184 bits (448), Expect = 2e-46
Identities = 86/188 (45%), Positives = 113/188 (60%), Gaps = 16/188 (8%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTN-------------- 242
FPDGF + V +A++Q EG W GK ++WD TH D N
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 243 -GDVACDSYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDAL 419
GDVA DSY+ D E L LGV YRFS+SW+R+LP G + N +G+RYY LL+ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 420 AEKNIEPLVTLFHWDLPQSLQD-LGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEP 596
E ++P+VTL+HWDLPQ LQD GGW N + D+FRDY+++C+R FG ++K WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 597 YEVCEDAY 620
Y V Y
Sbjct: 241 YVVAWHGY 248
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 184 bits (448), Expect = 2e-46
Identities = 86/188 (45%), Positives = 113/188 (60%), Gaps = 16/188 (8%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTN-------------- 242
FPDGF + V +A++Q EG W GK ++WD TH D N
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 243 -GDVACDSYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDAL 419
GDVA DSY+ D E L LGV YRFS+SW+R+LP G + N +G+RYY LL+ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 420 AEKNIEPLVTLFHWDLPQSLQD-LGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEP 596
E ++P+VTL+HWDLPQ LQD GGW N + D+FRDY+++C+R FG ++K WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 597 YEVCEDAY 620
Y V Y
Sbjct: 241 YVVAWHGY 248
Score = 83.4 bits (197), Expect = 6e-16
Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 9/174 (5%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWN-VSGKSENVWDRLTHTRPEMIADGT---NGDVACDSYHR 272
FP F +GV Q++ + + + +WD + H++ + DG C +
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD-VHHSKRLIKVDGVVTKKRKSYCVDFAA 577
Query: 273 YLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTL 452
+ L + V +RFSL W+ ILP G VN ++YY + L NI P+V L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 453 F-----HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPY 599
+ + LP+ L G W N F +Y+ +C++E G +K WIT+NEPY
Sbjct: 638 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPY 691
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 184 bits (448), Expect = 2e-46
Identities = 86/188 (45%), Positives = 113/188 (60%), Gaps = 16/188 (8%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTN-------------- 242
FPDGF + V +A++Q EG W GK ++WD TH D N
Sbjct: 61 FPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPLQPA 120
Query: 243 -GDVACDSYHRYLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDAL 419
GDVA DSY+ D E L LGV YRFS+SW+R+LP G + N +G+RYY LL+ L
Sbjct: 121 TGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLLERL 180
Query: 420 AEKNIEPLVTLFHWDLPQSLQD-LGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEP 596
E ++P+VTL+HWDLPQ LQD GGW N + D+FRDY+++C+R FG ++K WITI+ P
Sbjct: 181 RELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNP 240
Query: 597 YEVCEDAY 620
Y V Y
Sbjct: 241 YVVAWHGY 248
Score = 83.4 bits (197), Expect = 6e-16
Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 9/174 (5%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWN-VSGKSENVWDRLTHTRPEMIADGT---NGDVACDSYHR 272
FP F +GV Q++ + + + +WD + H++ + DG C +
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD-VHHSKRLIKVDGVVTKKRKSYCVDFAA 577
Query: 273 YLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTL 452
+ L + V +RFSL W+ ILP G VN ++YY + L NI P+V L
Sbjct: 578 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 637
Query: 453 F-----HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPY 599
+ + LP+ L G W N F +Y+ +C++E G +K WIT+NEPY
Sbjct: 638 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPY 691
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 184 bits (447), Expect = 3e-46
Identities = 77/163 (47%), Positives = 108/163 (66%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
FP GF + ATA++Q+EG W+ GK VWD TH E + GDVAC SY + ED
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTLFHWD 464
++ + LG+ YRFSLSWSR+LP G + +N GI YYN ++D L + + P+VTL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 465 LPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINE 593
LPQ+L+D GGW + +++ F Y+ C+ FGD++K WITINE
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINE 165
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99.1 bits (236), Expect = 1e-20
Identities = 44/96 (45%), Positives = 59/96 (61%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
FP GF + ATA++Q+EG W+ GK VWD TH E + GDVAC SY + ED
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIR 392
++ + LG+ YRFSLSWSR+LP G + +N I+
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQ 98
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99.1 bits (236), Expect = 1e-20
Identities = 44/96 (45%), Positives = 59/96 (61%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
FP GF + ATA++Q+EG W+ GK VWD TH E + GDVAC SY + ED
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIR 392
++ + LG+ YRFSLSWSR+LP G + +N I+
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQ 98
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 98.3 bits (234), Expect = 2e-20
Identities = 44/96 (45%), Positives = 59/96 (61%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWNVSGKSENVWDRLTHTRPEMIADGTNGDVACDSYHRYLED 284
FP GF + ATA++Q+EG W+ GK VWD TH E + GDVAC SY + ED
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 285 VEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIR 392
++ + LG+ YRFSLSWSR+LP G + +N I+
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAIQ 98
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 83.4 bits (197), Expect = 6e-16
Identities = 52/174 (29%), Positives = 82/174 (47%), Gaps = 9/174 (5%)
Frame = +3
Query: 105 FPDGFTFGVATASHQIEGAWN-VSGKSENVWDRLTHTRPEMIADGT---NGDVACDSYHR 272
FP F +GV Q++ + + + +WD + H++ + DG C +
Sbjct: 246 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD-VHHSKRLIKVDGVVTKKRKSYCVDFAA 304
Query: 273 YLEDVEELTYLGVDFYRFSLSWSRILPTGFSDHVNPDGIRYYNALLDALAEKNIEPLVTL 452
+ L + V +RFSL W+ ILP G VN ++YY + L NI P+V L
Sbjct: 305 IQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVAL 364
Query: 453 F-----HWDLPQSLQDLGGWTNSKMVDYFRDYSDVCYREFGDKIKSWITINEPY 599
+ + LP+ L G W N F +Y+ +C++E G +K WIT+NEPY
Sbjct: 365 WQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPY 418
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,592,453
Number of Sequences: 237096
Number of extensions: 2546458
Number of successful extensions: 9538
Number of sequences better than 10.0: 23
Number of HSP's better than 10.0 without gapping: 9076
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9496
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6804036910
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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