Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV14p09r
(727 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J03620-1|AAA35764.1| 509|Homo sapiens protein ( Human dihydroli... 260 3e-69
J03490-1|AAA59527.1| 509|Homo sapiens ZP3 protein. 260 3e-69
BC018696-1|AAH18696.1| 509|Homo sapiens dihydrolipoamide dehydr... 260 3e-69
BC018648-1|AAH18648.1| 509|Homo sapiens dihydrolipoamide dehydr... 260 3e-69
AB209703-1|BAD92940.1| 520|Homo sapiens Dihydrolipoamide dehydr... 260 3e-69
L13761-1|AAB01381.1| 511|Homo sapiens dihydrolipoamide dehydrog... 256 4e-68
BC117354-1|AAI17355.1| 492|Homo sapiens TXNRD2 protein protein. 72 2e-12
AF201385-1|AAG47635.1| 521|Homo sapiens mitochondrial thioredox... 72 2e-12
AF166127-1|AAF21432.1| 428|Homo sapiens selenoprotein Zf2 protein. 72 2e-12
AF166126-1|AAF21431.1| 277|Homo sapiens selenoprotein Zf1 protein. 72 2e-12
AB209724-1|BAD92961.1| 511|Homo sapiens thioredoxin reductase 2... 72 2e-12
AB019695-1|BAA77602.2| 494|Homo sapiens thioredoxin reductase I... 72 2e-12
AB019694-1|BAA77601.2| 524|Homo sapiens thioredoxin reductase I... 72 2e-12
BC007489-1|AAH07489.3| 485|Homo sapiens TXNRD2 protein protein. 71 3e-12
AF171054-1|AAD51324.1| 524|Homo sapiens thioredoxin reductase T... 71 3e-12
AF106697-1|AAD19597.1| 524|Homo sapiens thioredoxin reductase p... 71 3e-12
AF044212-1|AAD25167.1| 521|Homo sapiens thioredoxin reductase p... 71 3e-12
X15722-1|CAA33744.1| 479|Homo sapiens protein ( Human mRNA for ... 61 5e-09
BC069244-1|AAH69244.1| 522|Homo sapiens glutathione reductase p... 61 5e-09
AY338490-1|AAP88037.1| 479|Homo sapiens glutathione reductase p... 61 5e-09
AF228704-1|AAF37574.1| 522|Homo sapiens mitochondrial glutathio... 61 5e-09
AF228703-2|AAF37573.1| 479|Homo sapiens cytosolic glutathione r... 61 5e-09
AF228703-1|AAF37572.1| 522|Homo sapiens mitochondrial glutathio... 61 5e-09
X91247-1|CAA62629.1| 497|Homo sapiens thioredoxin reductase (NA... 60 6e-09
S79851-1|AAB35418.1| 497|Homo sapiens thioredoxin reductase pro... 60 6e-09
D88687-1|BAA13674.1| 549|Homo sapiens KM-102-derived reductase-... 60 6e-09
DQ157758-1|AAZ67916.1| 497|Homo sapiens thioredoxin reductase 1... 60 6e-09
CR536506-1|CAG38744.1| 497|Homo sapiens TXNRD1 protein. 60 6e-09
BT019640-1|AAV38446.1| 497|Homo sapiens thioredoxin reductase 1... 60 6e-09
BC050032-1|AAH50032.1| 681|Homo sapiens TXNRD3 protein protein. 60 6e-09
BC030028-1|AAH30028.1| 678|Homo sapiens TXNRD3 protein protein. 60 6e-09
BC018122-1|AAH18122.2| 499|Homo sapiens thioredoxin reductase 1... 60 6e-09
AY057105-1|AAL15432.1| 647|Homo sapiens thioredoxin reductase 1... 60 6e-09
AJ001050-1|CAA04503.1| 497|Homo sapiens thioredoxin reductase p... 60 6e-09
AF208018-1|AAF15900.1| 497|Homo sapiens thioredoxin reductase p... 60 6e-09
AF171055-1|AAD51325.1| 579|Homo sapiens thioredoxin reductase T... 60 6e-09
AF133519-1|AAD39929.1| 577|Homo sapiens thioredoxin reductase 3... 60 6e-09
AF077367-1|AAC69621.1| 497|Homo sapiens thioredoxin reductase G... 60 8e-09
AK128515-1|BAC87474.1| 581|Homo sapiens protein ( Homo sapiens ... 57 6e-08
AK026080-1|BAB15353.1| 863|Homo sapiens protein ( Homo sapiens ... 31 4.2
>J03620-1|AAA35764.1| 509|Homo sapiens protein ( Human
dihydrolipoamide dehydrogenase mRNA, complete cds. ).
Length = 509
Score = 260 bits (638), Expect = 3e-69
Identities = 116/165 (70%), Positives = 136/165 (82%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 547
T +P IYAIGDV+ GPMLAHKAEDEGI+CVEG+ G VH +Y+ +PSVIYT PEV WVGK
Sbjct: 345 TKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGK 404
Query: 546 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 367
+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG HI+GPG GE++
Sbjct: 405 SEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMV 464
Query: 366 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 232
NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK INF
Sbjct: 465 NEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 509
>J03490-1|AAA59527.1| 509|Homo sapiens ZP3 protein.
Length = 509
Score = 260 bits (638), Expect = 3e-69
Identities = 116/165 (70%), Positives = 136/165 (82%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 547
T +P IYAIGDV+ GPMLAHKAEDEGI+CVEG+ G VH +Y+ +PSVIYT PEV WVGK
Sbjct: 345 TKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGK 404
Query: 546 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 367
+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG HI+GPG GE++
Sbjct: 405 SEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMV 464
Query: 366 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 232
NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK INF
Sbjct: 465 NEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 509
>BC018696-1|AAH18696.1| 509|Homo sapiens dihydrolipoamide
dehydrogenase protein.
Length = 509
Score = 260 bits (638), Expect = 3e-69
Identities = 116/165 (70%), Positives = 136/165 (82%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 547
T +P IYAIGDV+ GPMLAHKAEDEGI+CVEG+ G VH +Y+ +PSVIYT PEV WVGK
Sbjct: 345 TKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGK 404
Query: 546 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 367
+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG HI+GPG GE++
Sbjct: 405 SEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMV 464
Query: 366 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 232
NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK INF
Sbjct: 465 NEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 509
>BC018648-1|AAH18648.1| 509|Homo sapiens dihydrolipoamide
dehydrogenase protein.
Length = 509
Score = 260 bits (638), Expect = 3e-69
Identities = 116/165 (70%), Positives = 136/165 (82%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 547
T +P IYAIGDV+ GPMLAHKAEDEGI+CVEG+ G VH +Y+ +PSVIYT PEV WVGK
Sbjct: 345 TKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGK 404
Query: 546 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 367
+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG HI+GPG GE++
Sbjct: 405 SEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMV 464
Query: 366 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 232
NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK INF
Sbjct: 465 NEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 509
>AB209703-1|BAD92940.1| 520|Homo sapiens Dihydrolipoamide
dehydrogenase, variant protein.
Length = 520
Score = 260 bits (638), Expect = 3e-69
Identities = 116/165 (70%), Positives = 136/165 (82%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 547
T +P IYAIGDV+ GPMLAHKAEDEGI+CVEG+ G VH +Y+ +PSVIYT PEV WVGK
Sbjct: 356 TKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGK 415
Query: 546 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 367
+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG HI+GPG GE++
Sbjct: 416 SEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMV 475
Query: 366 NEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPINF 232
NEA LA EYGA+ ED+ARVCHAHPT +EA REANLAA GK INF
Sbjct: 476 NEAALALEYGASCEDIARVCHAHPTLSEAFREANLAASFGKSINF 520
>L13761-1|AAB01381.1| 511|Homo sapiens dihydrolipoamide
dehydrogenase protein.
Length = 511
Score = 256 bits (628), Expect = 4e-68
Identities = 117/167 (70%), Positives = 136/167 (81%), Gaps = 2/167 (1%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGK 547
T +P IYAIGDV+ GPMLAHKAEDEGI+CVEG+ G VH +Y+ +PSVIYT PEV WVGK
Sbjct: 345 TKIPNIYAIGDVVAGPMLAHKAEDEGIICVEGMAGGAVHIDYNCVPSVIYTHPEVAWVGK 404
Query: 546 TEEDLKKEGRAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGGGELI 367
+EE LK+EG YKVGKFPF ANSRAKTN +T+G VK+L K+TD +LG HI+GPG GE++
Sbjct: 405 SEEQLKEEGIEYKVGKFPFAANSRAKTNADTDGMVKILGQKSTDRVLGAHILGPGAGEMV 464
Query: 366 NEAVLAQEYGAAAEDVARVCHAHPTC--AEALREANLAAYSGKPINF 232
NEA LA EYGA+ ED+ARVCHAHPT AEA REANLAA GK INF
Sbjct: 465 NEAALALEYGASCEDIARVCHAHPTLSEAEAFREANLAASFGKSINF 511
>BC117354-1|AAI17355.1| 492|Homo sapiens TXNRD2 protein protein.
Length = 492
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 319 TSVPHIYAIGDVVEGRPELTPTAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 378
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 379 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 438
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 439 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 484
>AF201385-1|AAG47635.1| 521|Homo sapiens mitochondrial thioredoxin
reductase protein.
Length = 521
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 348 TSVPHIYAIGDVVEGRPELTPTAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 407
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 408 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 467
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 468 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 513
>AF166127-1|AAF21432.1| 428|Homo sapiens selenoprotein Zf2 protein.
Length = 428
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 253 TSVPHIYAIGDVVEGRPELTPTAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 312
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 313 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 372
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 373 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 418
>AF166126-1|AAF21431.1| 277|Homo sapiens selenoprotein Zf1 protein.
Length = 277
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 102 TSVPHIYAIGDVVEGRPELTPTAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 161
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 162 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 221
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 222 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 267
>AB209724-1|BAD92961.1| 511|Homo sapiens thioredoxin reductase 2
isoform 1 precursor variant protein.
Length = 511
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 338 TSVPHIYAIGDVVEGRPELTPTAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 397
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 398 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 457
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 458 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 503
>AB019695-1|BAA77602.2| 494|Homo sapiens thioredoxin reductase II
beta protein.
Length = 494
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 319 TSVPHIYAIGDVVEGRPELTPTAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 378
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 379 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 438
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 439 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 484
>AB019694-1|BAA77601.2| 524|Homo sapiens thioredoxin reductase II
alpha protein.
Length = 524
Score = 72.1 bits (169), Expect = 2e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 349 TSVPHIYAIGDVVEGRPELTPTAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 408
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 409 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 468
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 469 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 514
>BC007489-1|AAH07489.3| 485|Homo sapiens TXNRD2 protein protein.
Length = 485
Score = 71.3 bits (167), Expect = 3e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 310 TSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 369
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 370 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 429
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 430 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 475
>AF171054-1|AAD51324.1| 524|Homo sapiens thioredoxin reductase TR3
protein.
Length = 524
Score = 71.3 bits (167), Expect = 3e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 349 TSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 408
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 409 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 468
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 469 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 514
>AF106697-1|AAD19597.1| 524|Homo sapiens thioredoxin reductase
protein.
Length = 524
Score = 71.3 bits (167), Expect = 3e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 349 TSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 408
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 409 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 468
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 469 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 514
>AF044212-1|AAD25167.1| 521|Homo sapiens thioredoxin reductase
protein.
Length = 521
Score = 71.3 bits (167), Expect = 3e-12
Identities = 50/166 (30%), Positives = 83/166 (50%), Gaps = 6/166 (3%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVHF-NYDAIPSVIYTSPEVGWV 553
T+VP IYAIGDV+ G P L A G + V+ + G +YD +P+ ++T E G V
Sbjct: 346 TSVPHIYAIGDVVEGRPELTPIAIMAGRLLVQRLFGGSSDLMDYDNVPTTVFTPLEYGCV 405
Query: 552 GKTEED-LKKEGRAYKVGKFPFLANSRAKTNGE--TEGFVKVLS-DKTTDVILGTHIIGP 385
G +EE+ + + G+ + G ++ +VK++ + ++LG H +GP
Sbjct: 406 GLSEEEAVARHGQEHVEVYHAHYKPLEFTVAGRDASQCYVKMVCLREPPQLVLGLHFLGP 465
Query: 384 GGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSG 247
GE+ L + GA+ V R HPTC+E + + ++ SG
Sbjct: 466 NAGEVTQGFALGIKCGASYAQVMRTVGIHPTCSEEVVKLRISKRSG 511
>X15722-1|CAA33744.1| 479|Homo sapiens protein ( Human mRNA for
glutathione reductase (EC 1.6.4.2). ).
Length = 479
Score = 60.9 bits (141), Expect = 5e-09
Identities = 44/154 (28%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH--FNYDAIPSVIYTSPEVGWV 553
T V GIYA+GDV +L A G + +Y+ IP+V+++ P +G V
Sbjct: 322 TNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTV 381
Query: 552 GKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 379
G TE++ + K G K F A T +T+ +K++ + ++G H+ G G
Sbjct: 382 GLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGC 441
Query: 378 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 277
E++ +A + GA D HPT +E L
Sbjct: 442 DEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 475
>BC069244-1|AAH69244.1| 522|Homo sapiens glutathione reductase
protein.
Length = 522
Score = 60.9 bits (141), Expect = 5e-09
Identities = 44/154 (28%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH--FNYDAIPSVIYTSPEVGWV 553
T V GIYA+GDV +L A G + +Y+ IP+V+++ P +G V
Sbjct: 365 TNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTV 424
Query: 552 GKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 379
G TE++ + K G K F A T +T+ +K++ + ++G H+ G G
Sbjct: 425 GLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGC 484
Query: 378 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 277
E++ +A + GA D HPT +E L
Sbjct: 485 DEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 518
>AY338490-1|AAP88037.1| 479|Homo sapiens glutathione reductase
protein.
Length = 479
Score = 60.9 bits (141), Expect = 5e-09
Identities = 44/154 (28%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH--FNYDAIPSVIYTSPEVGWV 553
T V GIYA+GDV +L A G + +Y+ IP+V+++ P +G V
Sbjct: 322 TNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTV 381
Query: 552 GKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 379
G TE++ + K G K F A T +T+ +K++ + ++G H+ G G
Sbjct: 382 GLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGC 441
Query: 378 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 277
E++ +A + GA D HPT +E L
Sbjct: 442 DEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 475
>AF228704-1|AAF37574.1| 522|Homo sapiens mitochondrial glutathione
reductase protein.
Length = 522
Score = 60.9 bits (141), Expect = 5e-09
Identities = 44/154 (28%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH--FNYDAIPSVIYTSPEVGWV 553
T V GIYA+GDV +L A G + +Y+ IP+V+++ P +G V
Sbjct: 365 TNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTV 424
Query: 552 GKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 379
G TE++ + K G K F A T +T+ +K++ + ++G H+ G G
Sbjct: 425 GLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGC 484
Query: 378 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 277
E++ +A + GA D HPT +E L
Sbjct: 485 DEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 518
>AF228703-2|AAF37573.1| 479|Homo sapiens cytosolic glutathione
reductase protein.
Length = 479
Score = 60.9 bits (141), Expect = 5e-09
Identities = 44/154 (28%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH--FNYDAIPSVIYTSPEVGWV 553
T V GIYA+GDV +L A G + +Y+ IP+V+++ P +G V
Sbjct: 322 TNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTV 381
Query: 552 GKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 379
G TE++ + K G K F A T +T+ +K++ + ++G H+ G G
Sbjct: 382 GLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGC 441
Query: 378 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 277
E++ +A + GA D HPT +E L
Sbjct: 442 DEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 475
>AF228703-1|AAF37572.1| 522|Homo sapiens mitochondrial glutathione
reductase protein.
Length = 522
Score = 60.9 bits (141), Expect = 5e-09
Identities = 44/154 (28%), Positives = 71/154 (46%), Gaps = 4/154 (2%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPMLAHKAEDEGIVCVEGIKGMPVH--FNYDAIPSVIYTSPEVGWV 553
T V GIYA+GDV +L A G + +Y+ IP+V+++ P +G V
Sbjct: 365 TNVKGIYAVGDVCGKALLTPVAIAAGRKLAHRLFEYKEDSKLDYNNIPTVVFSHPPIGTV 424
Query: 552 GKTEED-LKKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIGPGG 379
G TE++ + K G K F A T +T+ +K++ + ++G H+ G G
Sbjct: 425 GLTEDEAIHKYGIENVKTYSTSFTPMYHAVTKRKTKCVMKMVCANKEEKVVGIHMQGLGC 484
Query: 378 GELINEAVLAQEYGAAAEDVARVCHAHPTCAEAL 277
E++ +A + GA D HPT +E L
Sbjct: 485 DEMLQGFAVAVKMGATKADFDNTVAIHPTSSEEL 518
>X91247-1|CAA62629.1| 497|Homo sapiens thioredoxin reductase
(NADPH) protein.
Length = 497
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 324 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 383
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 384 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 442
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 443 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASI 492
>S79851-1|AAB35418.1| 497|Homo sapiens thioredoxin reductase
protein.
Length = 497
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 324 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 383
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 384 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 442
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 443 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASI 492
>D88687-1|BAA13674.1| 549|Homo sapiens KM-102-derived
reductase-like factor protein.
Length = 549
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 376 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 435
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 436 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 494
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 495 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASI 544
>DQ157758-1|AAZ67916.1| 497|Homo sapiens thioredoxin reductase 1
protein.
Length = 497
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 324 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 383
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 384 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 442
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 443 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASI 492
>CR536506-1|CAG38744.1| 497|Homo sapiens TXNRD1 protein.
Length = 497
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 324 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 383
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 384 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 442
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 443 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASI 492
>BT019640-1|AAV38446.1| 497|Homo sapiens thioredoxin reductase 1
protein.
Length = 497
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 324 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 383
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 384 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 442
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 443 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASI 492
>BC050032-1|AAH50032.1| 681|Homo sapiens TXNRD3 protein protein.
Length = 681
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVGWV 553
T VP +YA+GD++ P L A G + + + G + +Y +P+ ++T E G
Sbjct: 508 TNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCC 567
Query: 552 GKTEEDL----KKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT-DVILGTHII 391
G +EE KKE Y +P + N + K++ +K D ++G HI+
Sbjct: 568 GLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTC--YAKIICNKFDHDRVIGFHIL 625
Query: 390 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
GP GE+ A + G + + HPTC E + SG I
Sbjct: 626 GPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDI 676
>BC030028-1|AAH30028.1| 678|Homo sapiens TXNRD3 protein protein.
Length = 678
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVGWV 553
T VP +YA+GD++ P L A G + + + G + +Y +P+ ++T E G
Sbjct: 505 TNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCC 564
Query: 552 GKTEEDL----KKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT-DVILGTHII 391
G +EE KKE Y +P + N + K++ +K D ++G HI+
Sbjct: 565 GLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTC--YAKIICNKFDHDRVIGFHIL 622
Query: 390 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
GP GE+ A + G + + HPTC E + SG I
Sbjct: 623 GPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDI 673
>BC018122-1|AAH18122.2| 499|Homo sapiens thioredoxin reductase 1
protein.
Length = 499
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 324 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 383
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 384 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 442
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 443 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASI 492
>AY057105-1|AAL15432.1| 647|Homo sapiens thioredoxin reductase 1
protein.
Length = 647
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 474 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 533
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 534 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 592
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 593 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASI 642
>AJ001050-1|CAA04503.1| 497|Homo sapiens thioredoxin reductase
protein.
Length = 497
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 324 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 383
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 384 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 442
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 443 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASI 492
>AF208018-1|AAF15900.1| 497|Homo sapiens thioredoxin reductase
protein.
Length = 497
Score = 60.5 bits (140), Expect = 6e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 324 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 383
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 384 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 442
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 443 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGASI 492
>AF171055-1|AAD51325.1| 579|Homo sapiens thioredoxin reductase TR2
protein.
Length = 579
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVGWV 553
T VP +YA+GD++ P L A G + + + G + +Y +P+ ++T E G
Sbjct: 404 TNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCC 463
Query: 552 GKTEEDL----KKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT-DVILGTHII 391
G +EE KKE Y +P + N + K++ +K D ++G HI+
Sbjct: 464 GLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTC--YAKIICNKFDHDRVIGFHIL 521
Query: 390 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
GP GE+ A + G + + HPTC E + SG I
Sbjct: 522 GPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDI 572
>AF133519-1|AAD39929.1| 577|Homo sapiens thioredoxin reductase 3
protein.
Length = 577
Score = 60.5 bits (140), Expect = 6e-09
Identities = 46/171 (26%), Positives = 74/171 (43%), Gaps = 8/171 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHG-PMLAHKAEDEGIVCVEGIKGMPVH-FNYDAIPSVIYTSPEVGWV 553
T VP +YA+GD++ P L A G + + + G + +Y +P+ ++T E G
Sbjct: 402 TNVPYVYAVGDILEDKPELTPVAIQSGKLLAQRLFGASLEKCDYINVPTTVFTPLEYGCC 461
Query: 552 GKTEEDL----KKEG-RAYKVGKFPFLANSRAKTNGETEGFVKVLSDKTT-DVILGTHII 391
G +EE KKE Y +P + N + K++ +K D ++G HI+
Sbjct: 462 GLSEEKAIEVYKKENLEIYHTLFWPLEWTVAGRENNTC--YAKIICNKFDHDRVIGFHIL 519
Query: 390 GPGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
GP GE+ A + G + + HPTC E + SG I
Sbjct: 520 GPNAGEVTQGFAAAMKCGLTKQLLDDTIGIHPTCGEVFTTLEITKSSGLDI 570
>AF077367-1|AAC69621.1| 497|Homo sapiens thioredoxin reductase
GRIM-12 protein.
Length = 497
Score = 60.1 bits (139), Expect = 8e-09
Identities = 44/170 (25%), Positives = 77/170 (45%), Gaps = 7/170 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 324 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 383
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 384 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 442
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAEALREANLAAYSGKPI 238
P GE+ A + G + + HP CAE ++ SG I
Sbjct: 443 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAEVFTTLSVTKRSGARI 492
>AK128515-1|BAC87474.1| 581|Homo sapiens protein ( Homo sapiens
cDNA FLJ46672 fis, clone TRACH3009008, highly similar
to Thioredoxin reductase (EC 1.6.4.5). ).
Length = 581
Score = 57.2 bits (132), Expect = 6e-08
Identities = 41/155 (26%), Positives = 72/155 (46%), Gaps = 7/155 (4%)
Frame = -2
Query: 726 TTVPGIYAIGDVIHGPM-LAHKAEDEGIVCVEGI-KGMPVHFNYDAIPSVIYTSPEVGWV 553
T VP IYAIGD++ + L A G + + + G V +Y+ +P+ ++T E G
Sbjct: 423 TNVPYIYAIGDILEDKVELTPVAIQAGRLLAQRLYAGSTVKCDYENVPTTVFTPLEYGAC 482
Query: 552 GKTEED-LKKEGR----AYKVGKFPFLANSRAKTNGETEGFVKVLSDKTTDVILGTHIIG 388
G +EE ++K G Y +P ++ N + + + + K + ++G H++G
Sbjct: 483 GLSEEKAVEKFGEENIEVYHSYFWPLEWTIPSRDNNKCYAKI-ICNTKDNERVVGFHVLG 541
Query: 387 PGGGELINEAVLAQEYGAAAEDVARVCHAHPTCAE 283
P GE+ A + G + + HP CAE
Sbjct: 542 PNAGEVTQGFAAALKCGLTKKQLDSTIGIHPVCAE 576
>AK026080-1|BAB15353.1| 863|Homo sapiens protein ( Homo sapiens
cDNA: FLJ22427 fis, clone HRC09013. ).
Length = 863
Score = 31.1 bits (67), Expect = 4.2
Identities = 22/67 (32%), Positives = 30/67 (44%)
Frame = -2
Query: 699 GDVIHGPMLAHKAEDEGIVCVEGIKGMPVHFNYDAIPSVIYTSPEVGWVGKTEEDLKKEG 520
GDV+ P+ KAE E V VE PV +A P GW G+ +E+ G
Sbjct: 392 GDVLRPPLAGCKAELEAQVGVEQAASEPVVLPAEARRGPAANQP--GWRGELQEEGAVGG 449
Query: 519 RAYKVGK 499
A + G+
Sbjct: 450 AAEETGR 456
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,743,019
Number of Sequences: 237096
Number of extensions: 1967685
Number of successful extensions: 4556
Number of sequences better than 10.0: 40
Number of HSP's better than 10.0 without gapping: 4224
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4505
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8567175942
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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