Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV14b23r
(651 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3 prot... 134 2e-31
BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family... 134 2e-31
AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family... 134 2e-31
AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein. 134 2e-31
M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA... 129 7e-30
DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family ... 129 7e-30
DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family... 129 7e-30
BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfam... 129 7e-30
BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family... 129 7e-30
AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein. 129 7e-30
AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein. 129 7e-30
AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein. 129 7e-30
AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450 polypep... 129 7e-30
AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4 p... 129 7e-30
M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrom... 128 2e-29
J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipin... 128 2e-29
AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4 pro... 127 3e-29
X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for ... 126 5e-29
M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver glu... 126 5e-29
D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein. 126 5e-29
D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa pro... 126 9e-29
BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family... 126 9e-29
AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant... 126 9e-29
AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450 polypep... 126 9e-29
AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43... 123 5e-28
BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein. 122 8e-28
AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43... 122 8e-28
AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfami... 122 8e-28
AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43... 122 8e-28
AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfami... 122 8e-28
AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein. 122 8e-28
AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfami... 118 2e-26
AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein. 118 2e-26
BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein. 100 4e-21
AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein. 100 4e-21
AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein. 98 2e-20
AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein. 98 2e-20
AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family... 98 2e-20
AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family... 98 2e-20
BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family... 97 4e-20
AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein. 97 4e-20
AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform... 97 4e-20
AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein. 97 4e-20
AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein. 97 4e-20
AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein. 97 4e-20
AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein. 97 5e-20
D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV prot... 97 6e-20
AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family... 97 6e-20
AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein. 97 6e-20
AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4 omega-hy... 97 6e-20
AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4 omega-hy... 97 6e-20
AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein pr... 95 2e-19
AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein. 95 2e-19
BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family... 94 3e-19
AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2 pro... 94 3e-19
AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens ... 94 3e-19
AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens ... 94 3e-19
D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4 omega-hydr... 91 2e-18
BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein. 91 2e-18
BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family... 91 2e-18
BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family... 91 2e-18
BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family... 91 2e-18
AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfam... 91 2e-18
AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfami... 91 2e-18
AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein. 91 2e-18
AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4 omega-hy... 91 2e-18
U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein. 91 3e-18
AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase pr... 91 3e-18
M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase prot... 91 4e-18
BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase ... 91 4e-18
BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein. 91 4e-18
AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase ... 91 4e-18
AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase pr... 91 4e-18
AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase pr... 91 4e-18
AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase pr... 91 4e-18
AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase pr... 91 4e-18
AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase pr... 91 4e-18
AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase pr... 91 4e-18
AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase pr... 91 4e-18
AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase pr... 91 4e-18
S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxyl... 90 5e-18
S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxyl... 90 5e-18
BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family... 90 5e-18
BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family... 90 5e-18
BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family... 90 5e-18
AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens ... 90 5e-18
AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfam... 90 5e-18
AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase pr... 90 5e-18
AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase pr... 90 5e-18
AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22 pr... 90 7e-18
AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K p... 89 1e-17
L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein. 89 1e-17
D26481-1|BAA05491.1| 519|Homo sapiens fatty acids omega-hydroxy... 89 1e-17
D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxyl... 89 1e-17
AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family... 89 1e-17
AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family... 89 1e-17
D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase prot... 89 2e-17
AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family... 86 1e-16
AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid omega-hydrox... 86 1e-16
S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D 24-hy... 84 5e-16
BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family... 84 5e-16
AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylas... 84 5e-16
AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein. 84 5e-16
AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein. 84 5e-16
AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family... 84 5e-16
AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family... 84 5e-16
AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family... 84 5e-16
AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens ... 84 5e-16
AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens ... 84 5e-16
AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens ... 84 5e-16
X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein. 83 8e-16
X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for ... 83 1e-15
J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung cyto... 83 1e-15
DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family... 83 1e-15
BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family... 83 1e-15
AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P4... 83 1e-15
AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P4... 83 1e-15
AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein. 83 1e-15
AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family... 83 1e-15
AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family... 83 1e-15
AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family... 83 1e-15
AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family... 83 1e-15
AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family... 83 1e-15
AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family... 83 1e-15
AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein. 83 1e-15
L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3 ... 82 2e-15
BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family... 81 3e-15
AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxyl... 81 3e-15
AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein. 81 3e-15
BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein. 79 1e-14
BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein. 79 1e-14
AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family... 79 1e-14
AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family... 79 1e-14
AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin D-1-... 79 1e-14
AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 79 1e-14
AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin ... 79 1e-14
AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin D-1-a... 79 1e-14
AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 79 1e-14
AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 79 1e-14
AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3 1a... 79 1e-14
AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3 1-... 79 1e-14
AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein. 78 3e-14
BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family... 77 4e-14
AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, famil... 75 2e-13
U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase... 71 3e-12
D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase... 71 3e-12
AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein. 71 3e-12
BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family... 71 4e-12
AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens ... 71 5e-12
X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein. 70 6e-12
M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc prot... 70 6e-12
M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein. 70 6e-12
BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family... 70 6e-12
U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha demet... 69 1e-11
X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein. 69 1e-11
M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein. 69 1e-11
M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6 prot... 68 3e-11
M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoqu... 68 3e-11
M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein. 68 3e-11
DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 3e-11
DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 3e-11
DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6 pro... 68 3e-11
DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 3e-11
DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 3e-11
DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 3e-11
DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 3e-11
DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 3e-11
DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6 pro... 68 3e-11
BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family... 68 3e-11
BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family... 68 3e-11
AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6 prot... 68 3e-11
AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, famil... 68 3e-11
AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxyl... 68 3e-11
M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein. 68 3e-11
M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein. 68 3e-11
M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein. 68 3e-11
M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein. 68 3e-11
DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family... 68 3e-11
BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family... 68 3e-11
BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family... 68 3e-11
BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family... 68 3e-11
BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family... 68 3e-11
BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family... 68 3e-11
AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1 pro... 68 3e-11
AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family... 68 3e-11
BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family... 67 4e-11
BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family... 66 8e-11
DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6 pro... 66 1e-10
DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6 pro... 66 1e-10
DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6 pro... 66 1e-10
DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6 pro... 66 1e-10
DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6 pro... 66 1e-10
DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6 pro... 66 1e-10
DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6 pro... 66 1e-10
DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6 pro... 66 1e-10
CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein. 66 1e-10
BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family... 66 1e-10
BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family... 66 1e-10
BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family... 66 1e-10
BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein. 66 1e-10
U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450 monooxyge... 65 2e-10
BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family... 65 2e-10
AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family... 65 2e-10
AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase pro... 65 2e-10
AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein. 65 2e-10
Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein. 65 2e-10
M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein. 65 2e-10
M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrom... 65 2e-10
DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6 pro... 65 2e-10
BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family... 65 2e-10
AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family... 65 2e-10
AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family... 65 2e-10
AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2 pro... 65 2e-10
AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family... 64 3e-10
AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family... 64 3e-10
AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxyla... 64 3e-10
X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase... 64 4e-10
M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase pro... 64 4e-10
M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein. 64 4e-10
BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family... 64 4e-10
BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family... 64 4e-10
X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase (P-... 64 5e-10
X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120... 64 5e-10
M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein. 64 5e-10
D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase pr... 64 5e-10
Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for ... 63 7e-10
M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein. 63 7e-10
M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein. 63 7e-10
L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrom... 63 7e-10
DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family... 63 7e-10
BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family... 63 7e-10
BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family... 63 7e-10
BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family... 63 7e-10
BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family... 63 7e-10
BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family... 63 7e-10
BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family... 63 7e-10
AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein. 63 7e-10
AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein. 63 7e-10
AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2 pro... 63 7e-10
M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein. 62 2e-09
M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein. 62 2e-09
M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid 1... 61 3e-09
AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome P-45... 61 3e-09
X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase ... 61 4e-09
M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein. 61 4e-09
M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant 21... 61 4e-09
M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human 21-hydrox... 61 4e-09
M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein. 61 4e-09
M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein. 61 4e-09
BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family... 61 4e-09
BX679671-7|CAM26071.1| 464|Homo sapiens cytochrome P450, family... 61 4e-09
BC125182-1|AAI25183.1| 494|Homo sapiens cytochrome P450, family... 61 4e-09
BC125181-1|AAI25182.1| 495|Homo sapiens cytochrome P450, family... 61 4e-09
BC096287-1|AAH96287.1| 503|Homo sapiens cytochrome P450, family... 61 4e-09
BC096285-1|AAH96285.1| 574|Homo sapiens CYP11B1 protein protein. 61 4e-09
AM183951-1|CAJ75805.1| 494|Homo sapiens steroid 21-hydroxylase,... 61 4e-09
AM183947-1|CAJ75801.1| 494|Homo sapiens steroid 21-hydroxylase,... 61 4e-09
AM183946-1|CAJ75800.1| 494|Homo sapiens steroid 21-hydroxylase,... 61 4e-09
AM183945-1|CAJ75799.1| 494|Homo sapiens steroid 21-hydroxylase,... 61 4e-09
AM086565-1|CAJ31104.1| 494|Homo sapiens steroid 21-hydroxylase,... 61 4e-09
AM086564-1|CAJ31103.1| 494|Homo sapiens steroid 21-hydroxylase,... 61 4e-09
AL929593-2|CAI41778.1| 465|Homo sapiens cytochrome P450, family... 61 4e-09
AL929593-1|CAI41779.1| 495|Homo sapiens cytochrome P450, family... 61 4e-09
AL662849-19|CAI17480.1| 465|Homo sapiens cytochrome P450, famil... 61 4e-09
AL662849-18|CAI17479.1| 495|Homo sapiens cytochrome P450, famil... 61 4e-09
AL645922-24|CAI41754.1| 495|Homo sapiens cytochrome P450, famil... 61 4e-09
AL645922-23|CAI41755.1| 465|Homo sapiens cytochrome P450, famil... 61 4e-09
AL049547-7|CAB89301.1| 495|Homo sapiens dJ34F7.3 (cytochrome P4... 61 4e-09
AF077974-1|AAD45405.1| 403|Homo sapiens cytochrome P450 21-hydr... 61 4e-09
AF019413-2|AAB67982.1| 495|Homo sapiens cytochrome P450 21-hydr... 61 4e-09
X55764-1|CAA39290.1| 503|Homo sapiens protein ( Human mRNA for ... 60 5e-09
S46963-1|AAB23864.2| 477|Homo sapiens cytochrome P-450 protein. 60 5e-09
M21940-1|AAA52159.1| 383|Homo sapiens CYP2C protein. 60 5e-09
D00173-1|BAA00123.1| 487|Homo sapiens cytochrome P-450 protein. 60 5e-09
BC125054-1|AAI25055.1| 490|Homo sapiens cytochrome P450, family... 60 5e-09
BC067433-1|AAH67433.1| 493|Homo sapiens cytochrome P450, family... 60 5e-09
AY702706-1|AAT94065.1| 490|Homo sapiens cytochrome P450, family... 60 5e-09
AY341248-1|AAP88931.1| 490|Homo sapiens cytochrome P450, family... 60 5e-09
AM183949-1|CAJ75803.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 5e-09
AL359672-1|CAH71303.1| 490|Homo sapiens cytochrome P450, family... 60 5e-09
M17252-1|AAA59985.1| 230|Homo sapiens CYP21 protein. 60 7e-09
M12078-1|AAA52154.1| 192|Homo sapiens POR protein. 60 7e-09
AM183950-1|CAJ75804.1| 494|Homo sapiens steroid 21-hydroxylase,... 60 7e-09
AK223108-1|BAD96828.1| 512|Homo sapiens cytochrome P450, family... 60 7e-09
AK054616-1|BAB70774.1| 465|Homo sapiens protein ( Homo sapiens ... 60 7e-09
M61854-1|AAB59426.1| 490|Homo sapiens cytochrome protein. 60 9e-09
L39102-1|AAL31348.1| 217|Homo sapiens S-mephenytoin 4-hydroxyla... 60 9e-09
L07093-1|AAA36660.1| 468|Homo sapiens cytochrome P450 protein. 59 1e-08
J02843-1|AAA52155.1| 493|Homo sapiens protein ( Human cytochrom... 59 1e-08
J02625-1|AAA35743.1| 493|Homo sapiens protein ( Human cytochrom... 59 1e-08
DQ515958-1|ABF47105.1| 493|Homo sapiens cytochrome P450, family... 59 1e-08
DQ149222-1|AAZ77710.1| 493|Homo sapiens cytochrome P450 2E1 pro... 59 1e-08
AY796203-1|AAV41877.1| 490|Homo sapiens cytochrome P450, family... 59 1e-08
AL583836-2|CAH74068.1| 490|Homo sapiens cytochrome P450, family... 59 1e-08
AL161645-2|CAH70047.1| 493|Homo sapiens cytochrome P450, family... 59 1e-08
AL133513-2|CAH73444.1| 490|Homo sapiens cytochrome P450, family... 59 1e-08
AF182276-1|AAF13601.1| 493|Homo sapiens cytochrome P450-2E1 pro... 59 1e-08
AF084225-1|AAD13753.1| 462|Homo sapiens cytochrome P450 2E1 pro... 59 1e-08
L16876-1|AAA02630.1| 490|Homo sapiens cytochrome P-4502C18 prot... 59 2e-08
AM183948-1|CAJ75802.1| 494|Homo sapiens steroid 21-hydroxylase ... 59 2e-08
X65962-1|CAA46778.1| 356|Homo sapiens cytochrome P-450 II C pro... 58 2e-08
M61856-1|AAB59356.1| 490|Homo sapiens cytochrome protein. 58 2e-08
BX538127-1|CAD98029.1| 310|Homo sapiens hypothetical protein pr... 58 2e-08
BC096260-1|AAH96260.1| 431|Homo sapiens CYP2C18 protein protein. 58 2e-08
BC096258-1|AAH96258.1| 490|Homo sapiens cytochrome P450, family... 58 2e-08
BC096257-1|AAH96257.1| 490|Homo sapiens cytochrome P450, family... 58 2e-08
BC069666-1|AAH69666.1| 490|Homo sapiens cytochrome P450, family... 58 2e-08
AL583836-1|CAH74067.1| 490|Homo sapiens cytochrome P450, family... 58 2e-08
AK223510-1|BAD97230.1| 490|Homo sapiens cytochrome P450, family... 58 2e-08
M80646-1|AAA60617.1| 460|Homo sapiens thromboxane synthase prot... 58 3e-08
X04300-1|CAA27843.1| 512|Homo sapiens P-450 c protein. 58 4e-08
EF094025-1|ABK41999.1| 512|Homo sapiens cytochrome P450, family... 58 4e-08
BC142690-1|AAI42691.1| 357|Homo sapiens CYP4A22 protein protein. 58 4e-08
BC023019-1|AAH23019.1| 512|Homo sapiens cytochrome P450, family... 58 4e-08
AY310359-1|AAQ76692.1| 484|Homo sapiens cytochrome P450 1A1 var... 58 4e-08
AM236047-1|CAJ84704.1| 251|Homo sapiens cytochrome P450 1A1 pro... 58 4e-08
AK223113-1|BAD96833.1| 512|Homo sapiens cytochrome P450, family... 58 4e-08
AF253322-1|AAK25727.1| 512|Homo sapiens cytochrome P450 protein. 58 4e-08
X02612-1|CAA26458.1| 512|Homo sapiens cytochrome P(1)-450 protein. 57 5e-08
M24667-1|AAA52148.1| 256|Homo sapiens steroid 11-beta-hydroxyla... 57 5e-08
M12792-1|AAB59440.1| 494|Homo sapiens steroid 21-hydroxylase pr... 57 5e-08
M12079-1|AAA52152.1| 191|Homo sapiens POR protein. 57 5e-08
K03191-1|AAA52139.1| 512|Homo sapiens CYP1A1 protein. 57 5e-08
BC025761-1|AAH25761.2| 490|Homo sapiens cytochrome P450, family... 57 5e-08
BC067435-1|AAH67435.1| 493|Homo sapiens cytochrome P450, family... 57 6e-08
BC109205-1|AAI09206.1| 512|Homo sapiens cytochrome P450, family... 56 1e-07
BC069443-1|AAH69443.1| 512|Homo sapiens cytochrome P450, family... 56 1e-07
AF252297-1|AAF76003.1| 512|Homo sapiens cytochrome P450 retinoi... 56 1e-07
AC007002-1|AAY14690.1| 512|Homo sapiens unknown protein. 56 1e-07
AY513608-1|AAR90939.1| 494|Homo sapiens cytochrome P450 2A13 va... 56 1e-07
AY513606-1|AAR90937.1| 494|Homo sapiens cytochrome P450 2A13 va... 56 1e-07
AY513605-1|AAR90936.1| 494|Homo sapiens cytochrome P450 2A13 va... 56 1e-07
AY513604-1|AAR90935.1| 494|Homo sapiens cytochrome P450 2A13 va... 56 1e-07
AF209774-1|AAG35775.1| 494|Homo sapiens cytochrome P450 2A13 pr... 56 1e-07
AY513609-1|AAR90940.1| 494|Homo sapiens cytochrome P450 2A13 va... 55 2e-07
EF122241-1|ABO41976.1| 491|Homo sapiens cytochrome P450 2F1 var... 55 3e-07
AF372573-1|AAL69652.1| 495|Homo sapiens cytochrome P450 2F1 pro... 55 3e-07
J02906-1|AAA52156.1| 491|Homo sapiens CYP2F1 protein. 54 3e-07
X13897-1|CAA32097.1| 489|Homo sapiens protein ( Human mRNA for ... 54 6e-07
X13930-1|CAA32118.1| 494|Homo sapiens protein ( Human CYP2A4 mR... 53 8e-07
X13929-1|CAA32117.1| 448|Homo sapiens P-450 IIA3 protein (1 is ... 53 8e-07
M33318-1|AAA52067.1| 494|Homo sapiens CYP2A protein. 53 8e-07
BC096256-1|AAH96256.1| 494|Homo sapiens cytochrome P450, family... 53 8e-07
BC096255-1|AAH96255.1| 494|Homo sapiens cytochrome P450, family... 53 8e-07
BC096254-1|AAH96254.1| 494|Homo sapiens cytochrome P450, family... 53 8e-07
BC096253-1|AAH96253.3| 494|Homo sapiens cytochrome P450, family... 53 8e-07
AF182275-1|AAF13600.1| 494|Homo sapiens cytochrome P450-2A6 pro... 53 8e-07
U22027-1|AAB40518.1| 494|Homo sapiens cytochrome P450 protein. 53 1e-06
M33317-1|AAA52138.1| 494|Homo sapiens CYP2A protein. 53 1e-06
BC117165-1|AAI17166.1| 494|Homo sapiens cytochrome P450, family... 53 1e-06
BC033691-1|AAH33691.1| 504|Homo sapiens cytochrome P450, family... 53 1e-06
AY358603-1|AAQ88966.1| 504|Homo sapiens Cytochrome p450 protein. 53 1e-06
AK027605-1|BAB55227.1| 564|Homo sapiens protein ( Homo sapiens ... 53 1e-06
AF335278-1|AAK13498.1| 504|Homo sapiens cytochrome P450 2S1 pro... 53 1e-06
Y07508-1|CAA68807.1| 503|Homo sapiens protein ( Human mRNA for ... 52 2e-06
X13589-1|CAA31929.1| 503|Homo sapiens protein ( Human mRNA for ... 52 2e-06
U22029-1|AAB40520.1| 494|Homo sapiens cytochrome P450 protein. 52 2e-06
M30804-1|AAA35728.1| 503|Homo sapiens protein ( Human aromatase... 52 2e-06
M28420-1|AAA52141.1| 419|Homo sapiens cytochrome P-450 aromatas... 52 2e-06
M22246-1|AAA35557.1| 503|Homo sapiens protein ( Human aromatase... 52 2e-06
M18856-1|AAA35556.1| 419|Homo sapiens protein ( Human aromatase... 52 2e-06
J04127-1|AAA52132.1| 503|Homo sapiens CYP19 protein. 52 2e-06
DQ680079-1|ABG25922.1| 347|Homo sapiens truncated cytochrome P4... 52 2e-06
DQ118405-1|AAZ23558.1| 503|Homo sapiens cytochrome P450 subfami... 52 2e-06
BC107785-1|AAI07786.1| 503|Homo sapiens cytochrome P450, family... 52 2e-06
BC035959-1|AAH35959.1| 503|Homo sapiens cytochrome P450, family... 52 2e-06
AY957953-1|AAX44046.1| 503|Homo sapiens cytochrome P450, family... 52 2e-06
AY220845-1|AAO49806.1| 516|Homo sapiens cytochrome P450 protein. 50 5e-06
AB209700-1|BAD92937.1| 336|Homo sapiens cytochrome P450, family... 50 7e-06
U22028-1|AAB40519.1| 494|Homo sapiens cytochrome P450 protein. 49 2e-05
AM233517-1|CAJ80720.1| 175|Homo sapiens cytochrome P450 1A1 pro... 48 3e-05
EF122244-1|ABO41979.1| 216|Homo sapiens cytochrome P450 2F1 var... 46 1e-04
AL358613-1|CAH72802.2| 522|Homo sapiens cytochrome P450, family... 46 2e-04
M29874-1|AAA52144.1| 491|Homo sapiens CYP2B protein. 45 3e-04
DQ298753-1|ABB84469.1| 491|Homo sapiens cytochrome P450, family... 45 3e-04
BC067431-1|AAH67431.1| 491|Homo sapiens cytochrome P450, family... 45 3e-04
BC067430-1|AAH67430.1| 491|Homo sapiens cytochrome P450, family... 45 3e-04
AF182277-1|AAF13602.1| 491|Homo sapiens cytochrome P450-2B6 pro... 45 3e-04
AC023172-1|AAF32444.1| 491|Homo sapiens CYP2B6 protein. 45 3e-04
L36085-1|AAC01761.1| 441|Homo sapiens thromboxane A2 synthase p... 44 5e-04
L16883-1|AAD13467.1| 169|Homo sapiens cytochrome P-450 2C protein. 44 5e-04
AY356349-1|AAQ55485.1| 522|Homo sapiens cytochrome P450 protein. 43 8e-04
K03192-1|AAA52147.1| 331|Homo sapiens CYP1A1 protein. 41 0.003
M17398-1|AAA35740.1| 393|Homo sapiens protein ( Human cytochrom... 40 0.008
AJ877238-1|CAI47002.1| 97|Homo sapiens putative cytochrome P45... 40 0.010
BC109084-1|AAI09085.1| 448|Homo sapiens CYP24A1 protein protein. 39 0.018
BC109083-1|AAI09084.1| 448|Homo sapiens CYP24A1 protein protein. 39 0.018
AL138805-3|CAM27343.1| 448|Homo sapiens cytochrome P450, family... 39 0.018
BC010358-1|AAH10358.1| 469|Homo sapiens cytochrome P450, family... 38 0.023
AF237982-1|AAF63329.1| 469|Homo sapiens oxysterol 7alpha-hydrox... 38 0.023
AL591242-1|CAH73899.1| 469|Homo sapiens cytochrome P450, family... 38 0.031
AL035670-1|CAI20276.1| 469|Homo sapiens cytochrome P450, family... 38 0.031
AK127151-1|BAC86855.1| 146|Homo sapiens protein ( Homo sapiens ... 38 0.031
S77409-1|AAB34643.1| 228|Homo sapiens steroid 18-hydroxylase pr... 37 0.054
AF040259-1|AAD10199.1| 144|Homo sapiens cytochrome P450 1A1 pro... 37 0.072
X58904-1|CAA41707.1| 371|Homo sapiens steroid 21-monooxygenase ... 36 0.095
X58902-1|CAA41706.1| 372|Homo sapiens steroid 21-monooxygenase ... 36 0.095
X58900-1|CAA41704.1| 372|Homo sapiens steroid 21-monooxygenase ... 36 0.095
X58899-1|CAA41703.1| 368|Homo sapiens steroid 21-monooxygenase ... 36 0.095
X58898-1|CAA41702.1| 371|Homo sapiens steroid 21-monooxygenase ... 36 0.095
AF144566-1|AAD30164.1| 339|Homo sapiens cytochrome P450 epoxyge... 36 0.095
AY871801-1|AAX62803.1| 483|Homo sapiens cytochrome P450 family ... 36 0.13
AM233518-1|CAJ80721.1| 157|Homo sapiens cytochrome P450 1A1 pro... 36 0.13
AK127234-1|BAC86895.1| 130|Homo sapiens ). protein. 36 0.13
BC128535-1|AAI28536.1| 143|Homo sapiens CYP21A2 protein protein. 35 0.22
AJ563379-2|CAD91649.1| 84|Homo sapiens cytochrome P450 protein. 35 0.22
AC004914-2|AAP21887.1| 311|Homo sapiens unknown protein. 35 0.22
AC004914-1|AAD21788.1| 348|Homo sapiens unknown protein. 35 0.22
BC096286-1|AAH96286.1| 437|Homo sapiens cytochrome P450, family... 35 0.29
BC029155-1|AAH29155.1| 489|Homo sapiens CYP7B1 protein protein. 33 1.2
AF176805-1|AAK11850.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 33 1.2
AF127090-1|AAD20021.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 33 1.2
AF029403-1|AAC95426.1| 506|Homo sapiens oxysterol 7alpha-hydrox... 33 1.2
EF122243-1|ABO41978.1| 47|Homo sapiens cytochrome P450 2F1 var... 32 1.5
X56088-1|CAA39568.1| 504|Homo sapiens cholesterol 7-alpha-hydr... 31 4.7
AK094090-1|BAC04283.1| 153|Homo sapiens protein ( Homo sapiens ... 31 4.7
AK127739-1|BAC87108.1| 538|Homo sapiens hydrolase (CILP). prot... 30 6.2
M93133-1|AAA58435.1| 504|Homo sapiens cholesterol 7-alpha hydro... 30 8.2
BC112184-1|AAI12185.1| 504|Homo sapiens cytochrome P450, family... 30 8.2
BC101777-1|AAI01778.1| 504|Homo sapiens cytochrome P450, family... 30 8.2
BC040126-1|AAH40126.1| 659|Homo sapiens TRM1 tRNA methyltransfe... 30 8.2
BC018302-1|AAH18302.1| 630|Homo sapiens TRMT1 protein protein. 30 8.2
BC002492-1|AAH02492.1| 659|Homo sapiens TRM1 tRNA methyltransfe... 30 8.2
AK000251-1|BAA91031.1| 659|Homo sapiens protein ( Homo sapiens ... 30 8.2
AF196479-1|AAG28495.1| 659|Homo sapiens N2,N2-dimethylguanosine... 30 8.2
AF090941-1|AAF24053.1| 115|Homo sapiens PRO0650 protein. 30 8.2
AC005546-2|AAC33150.1| 656|Homo sapiens R29425_1 protein. 30 8.2
>J04813-1|AAA02993.1| 502|Homo sapiens cytochrome P450 PCN3
protein.
Length = 502
Score = 134 bits (325), Expect = 2e-31
Identities = 67/158 (42%), Positives = 97/158 (61%), Gaps = 1/158 (0%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+ AQ +F AG+ET+SS S+TL++LA H ++Q+++Q EID VL + YDA+++M
Sbjct: 295 LAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLP-NKAPPTYDAVVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L R C + I G+ I G ++IP A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVAIRLERTCKKDVEIN--GVFIPKGSMVVIPTYALHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEM 85
EFRP+RF+K + I + + PFG GPRNCIG R M
Sbjct: 412 EEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALM 449
>BC033862-1|AAH33862.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 protein.
Length = 502
Score = 134 bits (325), Expect = 2e-31
Identities = 67/158 (42%), Positives = 97/158 (61%), Gaps = 1/158 (0%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+ AQ +F AG+ET+SS S+TL++LA H ++Q+++Q EID VL + YDA+++M
Sbjct: 295 LAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLP-NKAPPTYDAVVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L R C + I G+ I G ++IP A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVAIRLERTCKKDVEIN--GVFIPKGSMVVIPTYALHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEM 85
EFRP+RF+K + I + + PFG GPRNCIG R M
Sbjct: 412 EEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALM 449
>AK223008-1|BAD96728.1| 502|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 5 variant protein.
Length = 502
Score = 134 bits (325), Expect = 2e-31
Identities = 67/158 (42%), Positives = 97/158 (61%), Gaps = 1/158 (0%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+ AQ +F AG+ET+SS S+TL++LA H ++Q+++Q EID VL + YDA+++M
Sbjct: 295 LAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLP-NKAPPTYDAVVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L R C + I G+ I G ++IP A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVAIRLERTCMKDVEIN--GVFIPKGSMVVIPTYALHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEM 85
EFRP+RF+K + I + + PFG GPRNCIG R M
Sbjct: 412 EEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALM 449
>AC005020-1|AAS02016.1| 502|Homo sapiens unknown protein.
Length = 502
Score = 134 bits (325), Expect = 2e-31
Identities = 67/158 (42%), Positives = 97/158 (61%), Gaps = 1/158 (0%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+ AQ +F AG+ET+SS S+TL++LA H ++Q+++Q EID VL + YDA+++M
Sbjct: 295 LAAQSIIFIFAGYETTSSVLSFTLYELATHPDVQQKLQKEIDAVLP-NKAPPTYDAVVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L R C + I G+ I G ++IP A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVAIRLERTCKKDVEIN--GVFIPKGSMVVIPTYALHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEM 85
EFRP+RF+K + I + + PFG GPRNCIG R M
Sbjct: 412 EEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALM 449
>M18907-1|AAA35745.1| 503|Homo sapiens protein ( Human P450 mRNA
encoding nifedipine oxidase, complete cds. ).
Length = 503
Score = 129 bits (312), Expect = 7e-30
Identities = 66/159 (41%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 450
>DQ924960-1|ABI96208.1| 503|Homo sapiens cytochrome P450 family 3
subfamily A polypeptide 4 protein.
Length = 503
Score = 129 bits (312), Expect = 7e-30
Identities = 66/159 (41%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 450
>DQ005611-1|AAY16980.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 129 bits (312), Expect = 7e-30
Identities = 66/159 (41%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 450
>BC101631-1|AAI01632.1| 503|Homo sapiens cytochrome P450, subfamily
IIIA, polypeptide 4 protein.
Length = 503
Score = 129 bits (312), Expect = 7e-30
Identities = 66/159 (41%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 450
>BC069418-1|AAH69418.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 4 protein.
Length = 503
Score = 129 bits (312), Expect = 7e-30
Identities = 66/159 (41%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 450
>AJ563377-1|CAD91345.1| 353|Homo sapiens cytochrome P450 protein.
Length = 353
Score = 129 bits (312), Expect = 7e-30
Identities = 66/159 (41%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 145 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 203
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 204 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 261
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 262 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 300
>AJ563376-2|CAD91645.1| 430|Homo sapiens cytochrome P450 protein.
Length = 430
Score = 129 bits (312), Expect = 7e-30
Identities = 66/159 (41%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 222 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 280
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 281 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 338
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 339 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 377
>AJ563375-1|CAD91343.1| 503|Homo sapiens cytochrome P450 protein.
Length = 503
Score = 129 bits (312), Expect = 7e-30
Identities = 66/159 (41%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 450
>AF280107-2|AAG32290.1| 503|Homo sapiens cytochrome P450
polypeptide 4 protein.
Length = 503
Score = 129 bits (312), Expect = 7e-30
Identities = 66/159 (41%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 450
>AF209389-1|AAF21034.1| 503|Homo sapiens cytochrome P450 IIIA4
protein.
Length = 503
Score = 129 bits (312), Expect = 7e-30
Identities = 66/159 (41%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 450
>M14096-1|AAA35744.1| 503|Homo sapiens protein ( Human cytochrome
P-450 nifedipine oxidase mRNA, complet cds. ).
Length = 503
Score = 128 bits (308), Expect = 2e-29
Identities = 65/159 (40%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I G ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGWVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I +++ PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALM 450
>J04449-1|AAA35747.1| 502|Homo sapiens cytochrome P450 nifedipine
oxidase protein.
Length = 502
Score = 128 bits (308), Expect = 2e-29
Identities = 65/159 (40%), Positives = 99/159 (62%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 294 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 352
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I G ++IP+ A+ D KY+ +P
Sbjct: 353 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGWVVMIPSYALHRDPKYWTEP 410
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I +++ PFG+GPRNCIG R M
Sbjct: 411 EKFLPERFSKKNKDNIDPYTYTPFGSGPRNCIGMRFALM 449
>AF182273-1|AAF13598.1| 503|Homo sapiens cytochrome P450-3A4
protein.
Length = 503
Score = 127 bits (307), Expect = 3e-29
Identities = 66/159 (41%), Positives = 98/159 (61%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGCETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 450
>X12387-1|CAA30944.1| 503|Homo sapiens protein ( Human mRNA for
cytochrome P-450 (cyp3 locus). ).
Length = 503
Score = 126 bits (305), Expect = 5e-29
Identities = 65/159 (40%), Positives = 98/159 (61%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 295 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I G ++IP+ A+ D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGWVVMIPSYALHRDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 450
>M13785-1|AAA35742.1| 504|Homo sapiens protein ( Human liver
glucocorticoid-inducible cytochrome P-450 (HLp) mRNA,
complete cds. ).
Length = 504
Score = 126 bits (305), Expect = 5e-29
Identities = 65/159 (40%), Positives = 98/159 (61%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 296 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 354
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I G ++IP+ A+ D KY+ +P
Sbjct: 355 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGWVVMIPSYALHRDPKYWTEP 412
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 413 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 451
>D00003-1|BAA00001.1| 504|Homo sapiens cytochrome P-450 protein.
Length = 504
Score = 126 bits (305), Expect = 5e-29
Identities = 65/159 (40%), Positives = 98/159 (61%), Gaps = 2/159 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L+M
Sbjct: 296 LVAQSIIFIFAGYETTSSVLSFIMYELATHPDVQQKLQEEIDAVLP-NKAPPTYDTVLQM 354
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I G ++IP+ A+ D KY+ +P
Sbjct: 355 EYLDMVVNETLRLFPIAMRLERVCKKDVEIN--GMFIPKGWVVMIPSYALHRDPKYWTEP 412
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEM 85
+F P+RF+K ++ I + + PFG+GPRNCIG R M
Sbjct: 413 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMRFALM 451
>D00408-1|BAA00310.1| 503|Homo sapiens cytochrome P-450 HFLa
protein.
Length = 503
Score = 126 bits (303), Expect = 9e-29
Identities = 62/155 (40%), Positives = 98/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
++AQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L++
Sbjct: 295 LMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLP-NKAPPTYDTVLQL 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ + +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYVLHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + + PFG+GPRNCIG R
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMR 446
>BC067436-1|AAH67436.1| 503|Homo sapiens cytochrome P450, family 3,
subfamily A, polypeptide 7 protein.
Length = 503
Score = 126 bits (303), Expect = 9e-29
Identities = 62/155 (40%), Positives = 98/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
++AQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L++
Sbjct: 295 LMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLP-NKAPPTYDTVLQL 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ + +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYVLHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + + PFG+GPRNCIG R
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMR 446
>AF315325-1|AAG48618.1| 535|Homo sapiens cytochrome P450 variant
3A7 protein.
Length = 535
Score = 126 bits (303), Expect = 9e-29
Identities = 62/155 (40%), Positives = 98/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
++AQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L++
Sbjct: 295 LMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLP-NKAPPTYDTVLQL 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ + +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYVLHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + + PFG+GPRNCIG R
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMR 446
>AF280107-3|AAG32289.1| 503|Homo sapiens cytochrome P450
polypeptide 7 protein.
Length = 503
Score = 126 bits (303), Expect = 9e-29
Identities = 62/155 (40%), Positives = 98/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
++AQ +F AG+ET+SS S+ +++LA H ++Q+++Q EID VL + YD +L++
Sbjct: 295 LMAQSIIFIFAGYETTSSVLSFIIYELATHPDVQQKVQKEIDTVLP-NKAPPTYDTVLQL 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP L RVC + I G+ I GV ++IP+ + +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVAMRLERVCKKDVEIN--GMFIPKGVVVMIPSYVLHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + + PFG+GPRNCIG R
Sbjct: 412 EKFLPERFSKKNKDNIDPYIYTPFGSGPRNCIGMR 446
>AY390424-1|AAQ92352.1| 503|Homo sapiens cytochrome P450 CYP3A43.3
protein.
Length = 503
Score = 123 bits (297), Expect = 5e-28
Identities = 58/155 (37%), Positives = 100/155 (64%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL+ + + YDA+++M
Sbjct: 295 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLA-NKAPVTYDALVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + ++PFGAGPRNCIG R
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMR 446
>BC100981-1|AAI00982.1| 393|Homo sapiens CYP3A43 protein protein.
Length = 393
Score = 122 bits (295), Expect = 8e-28
Identities = 58/155 (37%), Positives = 99/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL + + YDA+++M
Sbjct: 185 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQM 243
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 244 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 301
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + ++PFGAGPRNCIG R
Sbjct: 302 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMR 336
>AY390425-1|AAQ92353.1| 503|Homo sapiens cytochrome P450 CYP3A43.1
protein.
Length = 503
Score = 122 bits (295), Expect = 8e-28
Identities = 58/155 (37%), Positives = 99/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL + + YDA+++M
Sbjct: 295 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + ++PFGAGPRNCIG R
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMR 446
>AF337813-1|AAK38841.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 122 bits (295), Expect = 8e-28
Identities = 58/155 (37%), Positives = 99/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL + + YDA+++M
Sbjct: 295 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + ++PFGAGPRNCIG R
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMR 446
>AF319634-1|AAK00325.1| 503|Homo sapiens cytochrome P450 CYP3A43
protein.
Length = 503
Score = 122 bits (295), Expect = 8e-28
Identities = 58/155 (37%), Positives = 99/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL + + YDA+++M
Sbjct: 295 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + ++PFGAGPRNCIG R
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMR 446
>AF280108-1|AAG33009.1| 503|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 503
Score = 122 bits (295), Expect = 8e-28
Identities = 58/155 (37%), Positives = 99/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL + + YDA+++M
Sbjct: 295 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + ++PFGAGPRNCIG R
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMR 446
>AC011904-4|AAS07395.1| 503|Homo sapiens unknown protein.
Length = 503
Score = 122 bits (295), Expect = 8e-28
Identities = 58/155 (37%), Positives = 99/155 (63%), Gaps = 2/155 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL + + YDA+++M
Sbjct: 295 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+RF+K ++ I + ++PFGAGPRNCIG R
Sbjct: 412 EKFCPERFSKKNKDSIDLYRYIPFGAGPRNCIGMR 446
>AF280109-1|AAG33010.1| 504|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 504
Score = 118 bits (284), Expect = 2e-26
Identities = 58/156 (37%), Positives = 99/156 (63%), Gaps = 3/156 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL + + YDA+++M
Sbjct: 295 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 195 SEFRPK-RFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+ RF+K ++ I + ++PFGAGPRNCIG R
Sbjct: 412 EKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMR 447
>AC011904-5|AAS07394.1| 504|Homo sapiens unknown protein.
Length = 504
Score = 118 bits (284), Expect = 2e-26
Identities = 58/156 (37%), Positives = 99/156 (63%), Gaps = 3/156 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL + + YDA+++M
Sbjct: 295 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 195 SEFRPK-RFAKDSE--IKKFSFLPFGAGPRNCIGAR 97
+F P+ RF+K ++ I + ++PFGAGPRNCIG R
Sbjct: 412 EKFCPESRFSKKNKDSIDLYRYIPFGAGPRNCIGMR 447
>BC016853-1|AAH16853.1| 524|Homo sapiens CYP4F11 protein protein.
Length = 524
Score = 100 bits (240), Expect = 4e-21
Identities = 54/160 (33%), Positives = 91/160 (56%), Gaps = 3/160 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLC 397
E+ + I A+ F G +T++S S+ L+ LA H E Q++ + E+ E+L R ++
Sbjct: 312 ELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIE 371
Query: 396 YDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+D + ++P LTM KE+LR+ P + + R CT+ + +P+ G I G+ +I I +
Sbjct: 372 WDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPD-GRVIPKGIVCLINIIGIHYN 430
Query: 216 AKYFDDPSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
+ DP + P RF +++ E +F+PF AGPRNCIG
Sbjct: 431 PTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIG 470
>AF236085-1|AAG15889.1| 524|Homo sapiens CYP4F11 protein.
Length = 524
Score = 100 bits (240), Expect = 4e-21
Identities = 54/160 (33%), Positives = 91/160 (56%), Gaps = 3/160 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLC 397
E+ + I A+ F G +T++S S+ L+ LA H E Q++ + E+ E+L R ++
Sbjct: 312 ELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQELLKDREPIEIE 371
Query: 396 YDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+D + ++P LTM KE+LR+ P + + R CT+ + +P+ G I G+ +I I +
Sbjct: 372 WDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPD-GRVIPKGIVCLINIIGIHYN 430
Query: 216 AKYFDDPSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
+ DP + P RF +++ E +F+PF AGPRNCIG
Sbjct: 431 PTVWPDPEVYDPFRFNQENIKERSPLAFIPFSAGPRNCIG 470
>AY358631-1|AAQ88994.1| 505|Homo sapiens EPSW3060 protein.
Length = 505
Score = 98.3 bits (234), Expect = 2e-20
Identities = 51/151 (33%), Positives = 92/151 (60%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F AG +T+SSA S+ L+ LA + E Q+ + EI E+L + + ++ + +MP
Sbjct: 306 AEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLG-DGSSITWEHLSQMPY 364
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE LR++ + N+ R+ + T P+ G ++ G+ + I A+ ++ +++DP
Sbjct: 365 TTMCIKECLRLYAPVVNISRLLDKPITFPD-GRSLPAGITVFINIWALHHNPYFWEDPQV 423
Query: 189 FRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
F P RF++++ +I ++F+PF AG RNCIG
Sbjct: 424 FNPLRFSRENSEKIHPYAFIPFSAGLRNCIG 454
>AY262056-1|AAO89257.1| 505|Homo sapiens cytochrome P450 protein.
Length = 505
Score = 98.3 bits (234), Expect = 2e-20
Identities = 51/151 (33%), Positives = 92/151 (60%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F AG +T+SSA S+ L+ LA + E Q+ + EI E+L + + ++ + +MP
Sbjct: 306 AEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLG-DGSSITWEHLSQMPY 364
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE LR++ + N+ R+ + T P+ G ++ G+ + I A+ ++ +++DP
Sbjct: 365 TTMCIKECLRLYAPVVNISRLLDKPITFPD-GRSLPAGITVFINIWALHHNPYFWEDPQV 423
Query: 189 FRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
F P RF++++ +I ++F+PF AG RNCIG
Sbjct: 424 FNPLRFSRENSEKIHPYAFIPFSAGLRNCIG 454
>AL450996-2|CAH71036.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 98.3 bits (234), Expect = 2e-20
Identities = 51/151 (33%), Positives = 92/151 (60%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F AG +T+SSA S+ L+ LA + E Q+ + EI E+L + + ++ + +MP
Sbjct: 306 AEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLG-DGSSITWEHLSQMPY 364
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE LR++ + N+ R+ + T P+ G ++ G+ + I A+ ++ +++DP
Sbjct: 365 TTMCIKECLRLYAPVVNISRLLDKPITFPD-GRSLPAGITVFINIWALHHNPYFWEDPQV 423
Query: 189 FRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
F P RF++++ +I ++F+PF AG RNCIG
Sbjct: 424 FNPLRFSRENSEKIHPYAFIPFSAGLRNCIG 454
>AL135960-6|CAI19734.1| 505|Homo sapiens cytochrome P450, family 4,
subfamily Z, polypeptide 1 protein.
Length = 505
Score = 98.3 bits (234), Expect = 2e-20
Identities = 51/151 (33%), Positives = 92/151 (60%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F AG +T+SSA S+ L+ LA + E Q+ + EI E+L + + ++ + +MP
Sbjct: 306 AEVKTFMFAGHDTTSSAISWILYCLAKYPEHQQRCRDEIRELLG-DGSSITWEHLSQMPY 364
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE LR++ + N+ R+ + T P+ G ++ G+ + I A+ ++ +++DP
Sbjct: 365 TTMCIKECLRLYAPVVNISRLLDKPITFPD-GRSLPAGITVFINIWALHHNPYFWEDPQV 423
Query: 189 FRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
F P RF++++ +I ++F+PF AG RNCIG
Sbjct: 424 FNPLRFSRENSEKIHPYAFIPFSAGLRNCIG 454
>BC035350-1|AAH35350.1| 524|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 12 protein.
Length = 524
Score = 97.5 bits (232), Expect = 4e-20
Identities = 52/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNK-LCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L D K + +D + +
Sbjct: 318 IRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQ 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + R CT+ +P+ G I G+ +I + ++ + D
Sbjct: 378 LPFLTMCVKESLRLHPPAPFISRCCTQDIVLPD-GRVIPKGITCLIDIIGVHHNPTVWPD 436
Query: 198 PSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
P + P RF ++ + +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIG 470
>AY358977-1|AAQ89336.1| 524|Homo sapiens CYP4F12 protein.
Length = 524
Score = 97.5 bits (232), Expect = 4e-20
Identities = 52/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNK-LCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L D K + +D + +
Sbjct: 318 IRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQ 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + R CT+ +P+ G I G+ +I + ++ + D
Sbjct: 378 LPFLTMCVKESLRLHPPAPFISRCCTQDIVLPD-GRVIPKGITCLIDIIGVHHNPTVWPD 436
Query: 198 PSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
P + P RF ++ + +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIG 470
>AY008841-1|AAG33247.1| 524|Homo sapiens cytochrome P450 isoform
4F12 protein.
Length = 524
Score = 97.5 bits (232), Expect = 4e-20
Identities = 52/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNK-LCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L D K + +D + +
Sbjct: 318 IRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQ 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + R CT+ +P+ G I G+ +I + ++ + D
Sbjct: 378 LPFLTMCVKESLRLHPPAPFISRCCTQDIVLPD-GRVIPKGITCLIDIIGVHHNPTVWPD 436
Query: 198 PSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
P + P RF ++ + +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIG 470
>AC004523-1|AAC11543.1| 458|Homo sapiens F22329_1 protein.
Length = 458
Score = 97.5 bits (232), Expect = 4e-20
Identities = 52/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNK-LCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L D K + +D + +
Sbjct: 252 IRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQ 311
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + R CT+ +P+ G I G+ +I + ++ + D
Sbjct: 312 LPFLTMCVKESLRLHPPAPFISRCCTQDIVLPD-GRVIPKGITCLIDIIGVHHNPTVWPD 370
Query: 198 PSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
P + P RF ++ + +F+PF AGPRNCIG
Sbjct: 371 PEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIG 404
>AB035131-1|BAB18270.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 97.5 bits (232), Expect = 4e-20
Identities = 52/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNK-LCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L D K + +D + +
Sbjct: 318 IRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQ 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + R CT+ +P+ G I G+ +I + ++ + D
Sbjct: 378 LPFLTMCVKESLRLHPPAPFISRCCTQDIVLPD-GRVIPKGITCLIDIIGVHHNPTVWPD 436
Query: 198 PSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
P + P RF ++ + +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIG 470
>AB035130-1|BAB18269.1| 524|Homo sapiens cytochrome P450 protein.
Length = 524
Score = 97.5 bits (232), Expect = 4e-20
Identities = 52/154 (33%), Positives = 85/154 (55%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNK-LCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L D K + +D + +
Sbjct: 318 IRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDRDPKEIEWDDLAQ 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + R CT+ +P+ G I G+ +I + ++ + D
Sbjct: 378 LPFLTMCVKESLRLHPPAPFISRCCTQDIVLPD-GRVIPKGITCLIDIIGVHHNPTVWPD 436
Query: 198 PSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
P + P RF ++ + +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIG 470
>AF133298-1|AAD49566.1| 520|Homo sapiens cytochrome P450 protein.
Length = 520
Score = 97.1 bits (231), Expect = 5e-20
Identities = 54/162 (33%), Positives = 89/162 (54%), Gaps = 3/162 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLC 397
E+ + I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++
Sbjct: 312 ELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQELLKDREPKEIE 371
Query: 396 YDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+D + ++P LTM KE+LR+ P + R CT+ +P+ + I G I AI ++
Sbjct: 372 WDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRV-IPKGNVCNINIFAIHHN 430
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIGAR 97
+ DP + P RF ++ K+ +F+PF AGPRNCIG +
Sbjct: 431 PSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQK 472
>D12620-1|BAA02144.1| 520|Homo sapiens cytochrome P-450LTBV
protein.
Length = 520
Score = 96.7 bits (230), Expect = 6e-20
Identities = 55/167 (32%), Positives = 90/167 (53%), Gaps = 5/167 (2%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D + +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQ 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R CT+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGA--RLGEMQSLAG 70
P + P RF + E +F+PF AGPRNCIG + EM+ + G
Sbjct: 437 PEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
>AY792513-1|AAV40834.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 3 protein.
Length = 520
Score = 96.7 bits (230), Expect = 6e-20
Identities = 55/167 (32%), Positives = 90/167 (53%), Gaps = 5/167 (2%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D + +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQ 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R CT+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGA--RLGEMQSLAG 70
P + P RF + E +F+PF AGPRNCIG + EM+ + G
Sbjct: 437 PEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
>AF054821-1|AAC08589.1| 520|Homo sapiens cytochrome P-450 protein.
Length = 520
Score = 96.7 bits (230), Expect = 6e-20
Identities = 55/167 (32%), Positives = 90/167 (53%), Gaps = 5/167 (2%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D + +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQ 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R CT+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGA--RLGEMQSLAG 70
P + P RF + E +F+PF AGPRNCIG + EM+ + G
Sbjct: 437 PEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
>AB002461-1|BAA25991.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 96.7 bits (230), Expect = 6e-20
Identities = 55/167 (32%), Positives = 90/167 (53%), Gaps = 5/167 (2%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D + +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQ 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R CT+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGA--RLGEMQSLAG 70
P + P RF + E +F+PF AGPRNCIG + EM+ + G
Sbjct: 437 PEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
>AB002454-1|BAA25990.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 96.7 bits (230), Expect = 6e-20
Identities = 55/167 (32%), Positives = 90/167 (53%), Gaps = 5/167 (2%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D + +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAQ 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R CT+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGA--RLGEMQSLAG 70
P + P RF + E +F+PF AGPRNCIG + EM+ + G
Sbjct: 437 PEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKVVLG 483
>AJ563378-3|CAD91347.1| 173|Homo sapiens hypothetical protein
protein.
Length = 173
Score = 95.1 bits (226), Expect = 2e-19
Identities = 45/105 (42%), Positives = 62/105 (59%), Gaps = 1/105 (0%)
Frame = -1
Query: 396 YDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
YDA+++M L M E LR+FP L R C + I G+ I G ++IP A+ +D
Sbjct: 18 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEIN--GVFIPKGSMVVIPTYALHHD 75
Query: 216 AKYFDDPSEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEM 85
KY+ +P EFRP+RF+K + I + + PFG GPRNCIG R M
Sbjct: 76 PKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALM 120
>AJ563378-2|CAD91647.1| 160|Homo sapiens cytochrome P450 protein.
Length = 160
Score = 95.1 bits (226), Expect = 2e-19
Identities = 45/105 (42%), Positives = 62/105 (59%), Gaps = 1/105 (0%)
Frame = -1
Query: 396 YDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
YDA+++M L M E LR+FP L R C + I G+ I G ++IP A+ +D
Sbjct: 5 YDAVVQMEYLDMVVNETLRLFPVAIRLERTCKKDVEIN--GVFIPKGSMVVIPTYALHHD 62
Query: 216 AKYFDDPSEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEM 85
KY+ +P EFRP+RF+K + I + + PFG GPRNCIG R M
Sbjct: 63 PKYWTEPEEFRPERFSKKKDSIDPYIYTPFGTGPRNCIGMRFALM 107
>BC060857-1|AAH60857.1| 525|Homo sapiens cytochrome P450, family 4,
subfamily V, polypeptide 2 protein.
Length = 525
Score = 94.3 bits (224), Expect = 3e-19
Identities = 46/153 (30%), Positives = 85/153 (55%), Gaps = 2/153 (1%)
Frame = -1
Query: 534 FXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAF 355
F G +T+++A +++L+ L + E+QK++ E+D+V + D + + ++ L
Sbjct: 326 FMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVI 385
Query: 354 KEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
KE LR+FPS+ R + + G + G +I A+ D +YF +P EF+P+R
Sbjct: 386 KETLRLFPSVPLFARSVSEDCEV--AGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPER 443
Query: 174 FAKDSEIKK--FSFLPFGAGPRNCIGARLGEMQ 82
F ++ + ++++PF AGPRNCIG + M+
Sbjct: 444 FFPENAQGRHPYAYVPFSAGPRNCIGQKFAVME 476
>AY422002-1|AAR31180.1| 525|Homo sapiens cytochrome P450 4V2
protein.
Length = 525
Score = 94.3 bits (224), Expect = 3e-19
Identities = 46/153 (30%), Positives = 85/153 (55%), Gaps = 2/153 (1%)
Frame = -1
Query: 534 FXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAF 355
F G +T+++A +++L+ L + E+QK++ E+D+V + D + + ++ L
Sbjct: 326 FMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVI 385
Query: 354 KEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
KE LR+FPS+ R + + G + G +I A+ D +YF +P EF+P+R
Sbjct: 386 KETLRLFPSVPLFARSVSEDCEV--AGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPER 443
Query: 174 FAKDSEIKK--FSFLPFGAGPRNCIGARLGEMQ 82
F ++ + ++++PF AGPRNCIG + M+
Sbjct: 444 FFPENAQGRHPYAYVPFSAGPRNCIGQKFAVME 476
>AK126473-1|BAC86562.1| 503|Homo sapiens protein ( Homo sapiens
cDNA FLJ44509 fis, clone UTERU3001585, weakly similar
to Cytochrome P450 4c3 (EC 1.14.-.-). ).
Length = 503
Score = 94.3 bits (224), Expect = 3e-19
Identities = 46/153 (30%), Positives = 85/153 (55%), Gaps = 2/153 (1%)
Frame = -1
Query: 534 FXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAF 355
F G +T+++A +++L+ L + E+QK++ E+D+V + D + + ++ L
Sbjct: 304 FMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVI 363
Query: 354 KEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
KE LR+FPS+ R + + G + G +I A+ D +YF +P EF+P+R
Sbjct: 364 KETLRLFPSVPLFARSVSEDCEV--AGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPER 421
Query: 174 FAKDSEIKK--FSFLPFGAGPRNCIGARLGEMQ 82
F ++ + ++++PF AGPRNCIG + M+
Sbjct: 422 FFPENAQGRHPYAYVPFSAGPRNCIGQKFAVME 454
>AK122600-1|BAC85487.1| 525|Homo sapiens protein ( Homo sapiens
cDNA FLJ16007 fis, clone KIDNE2006580, weakly similar
to CYTOCHROME P450 4C1 (EC 1.14.14.1). ).
Length = 525
Score = 94.3 bits (224), Expect = 3e-19
Identities = 46/153 (30%), Positives = 85/153 (55%), Gaps = 2/153 (1%)
Frame = -1
Query: 534 FXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAF 355
F G +T+++A +++L+ L + E+QK++ E+D+V + D + + ++ L
Sbjct: 326 FMFEGHDTTAAAINWSLYLLGSNPEVQKKVDHELDDVFGKSDRPATVEDLKKLRYLECVI 385
Query: 354 KEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
KE LR+FPS+ R + + G + G +I A+ D +YF +P EF+P+R
Sbjct: 386 KETLRLFPSVPLFARSVSEDCEV--AGYRVLKGTEAVIIPYALHRDPRYFPNPEEFQPER 443
Query: 174 FAKDSEIKK--FSFLPFGAGPRNCIGARLGEMQ 82
F ++ + ++++PF AGPRNCIG + M+
Sbjct: 444 FFPENAQGRHPYAYVPFSAGPRNCIGQKFAVME 476
>D26480-1|BAA05490.1| 520|Homo sapiens leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 91.5 bits (217), Expect = 2e-18
Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAH 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R T+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
P + P RF ++ E +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470
>BC100982-1|AAI00983.1| 280|Homo sapiens CYP3A43 protein protein.
Length = 280
Score = 91.5 bits (217), Expect = 2e-18
Identities = 43/127 (33%), Positives = 78/127 (61%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL + + YDA+++M
Sbjct: 155 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQM 213
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 214 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 271
Query: 195 SEFRPKR 175
+F P+R
Sbjct: 272 EKFCPER 278
>BC067440-1|AAH67440.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 91.5 bits (217), Expect = 2e-18
Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAH 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R T+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPD-GRVIPKGIICLISVFGTHHNPAMWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
P + P RF ++ E +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470
>BC067439-1|AAH67439.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 91.5 bits (217), Expect = 2e-18
Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAH 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R T+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
P + P RF ++ E +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470
>BC067437-1|AAH67437.1| 520|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 2 protein.
Length = 520
Score = 91.5 bits (217), Expect = 2e-18
Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAH 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R T+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
P + P RF ++ E +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470
>AF467894-1|AAL67578.1| 520|Homo sapiens cytochrome P450, subfamily
IVF, polypeptide 2 protein.
Length = 520
Score = 91.5 bits (217), Expect = 2e-18
Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAH 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R T+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
P + P RF ++ E +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470
>AF280110-1|AAG33011.1| 420|Homo sapiens cytochrome P450 subfamily
IIIA polypeptide 43 protein.
Length = 420
Score = 91.5 bits (217), Expect = 2e-18
Identities = 43/127 (33%), Positives = 78/127 (61%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VAQ + A ++T+S+ + +++LA H ++Q+++Q EID VL + + YDA+++M
Sbjct: 295 LVAQSIIIIFAAYDTTSTTLPFIMYELATHPDVQQKLQEEIDAVLP-NKAPVTYDALVQM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
L M E LR+FP + + RVC + I G+ I G+ +++P A+ +D KY+ +P
Sbjct: 354 EYLDMVVNETLRLFPVVSRVTRVCKKDIEIN--GVFIPKGLAVMVPIYALHHDPKYWTEP 411
Query: 195 SEFRPKR 175
+F P+R
Sbjct: 412 EKFCPER 418
>AC005336-1|AAC27730.1| 520|Homo sapiens CYP4F2 protein.
Length = 520
Score = 91.5 bits (217), Expect = 2e-18
Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAH 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R T+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
P + P RF ++ E +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470
>AB015306-1|BAA75823.1| 520|Homo sapiens Leukotriene B4
omega-hydroxylase protein.
Length = 520
Score = 91.5 bits (217), Expect = 2e-18
Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D +
Sbjct: 318 IRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAH 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R T+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCMKESLRLHPPVPVISRHVTQDIVLPD-GRVIPKGIICLISVFGTHHNPAMWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
P + P RF ++ E +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470
>U02388-1|AAC50052.2| 520|Homo sapiens cytochrome P450 4F2 protein.
Length = 520
Score = 91.1 bits (216), Expect = 3e-18
Identities = 51/154 (33%), Positives = 83/154 (53%), Gaps = 3/154 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLCYDAILE 379
I A+ F G +T++S S+ L+ LA H E Q+ + E+ E+L R ++ +D +
Sbjct: 318 IRAEADTFMFEGHDTTASVLSWVLYHLAKHPEYQERCRQEVQELLKDREPKEIEWDDLAH 377
Query: 378 MPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDD 199
+P LTM KE+LR+ P + + R T+ +P+ G I G+ +I ++ + D
Sbjct: 378 LPFLTMCMKESLRVHPPVPVISRHVTQDIVLPD-GRVIPKGIICLISVFGTHHNPAVWPD 436
Query: 198 PSEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIG 103
P + P RF ++ E +F+PF AGPRNCIG
Sbjct: 437 PEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIG 470
>AF233624-1|AAF99278.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 91.1 bits (216), Expect = 3e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ENFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>M80647-1|AAA60618.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>BC041157-1|AAH41157.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A)
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>BC014117-1|AAH14117.1| 466|Homo sapiens TBXAS1 protein protein.
Length = 466
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 264 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 323
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 324 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 381
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 382 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 421
>AK223466-1|BAD97186.1| 534|Homo sapiens thromboxane A synthase 1
(platelet, cytochrome P450, family 5, subfamily A) iso
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>AF233623-1|AAF99277.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 KTFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>AF233621-1|AAF99275.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYVLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>AF233620-1|AAF99274.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>AF233619-1|AAF99273.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>AF233618-1|AAF99272.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>AF233617-1|AAF99271.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>AF233616-1|AAF99270.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>AF233615-1|AAF99269.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.6 bits (215), Expect = 4e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>S67581-1|AAB29503.1| 591|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 591
Score = 90.2 bits (214), Expect = 5e-18
Identities = 48/156 (30%), Positives = 84/156 (53%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIG 103
+ +P F P RFA S +FLPF G RNCIG
Sbjct: 424 VWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIG 459
>S67580-1|AAB29502.1| 519|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 519
Score = 90.2 bits (214), Expect = 5e-18
Identities = 48/156 (30%), Positives = 84/156 (53%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIG 103
+ +P F P RFA S +FLPF G RNCIG
Sbjct: 424 VWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIG 459
>BC093896-1|AAH93896.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 90.2 bits (214), Expect = 5e-18
Identities = 51/160 (31%), Positives = 86/160 (53%), Gaps = 3/160 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLC 397
E+ + I A+ F G +T+SS S+ L LA + E Q++ + EI EV+ R +L
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378
Query: 396 YDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+D + ++P TM KE+LR +P + + R CT +P+ G I G+ ++ ++
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPD-GRIIPKGIICLVSIYGTHHN 437
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
+ D + P RF D+ ++ +++PF AGPRNCIG
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIG 477
>BC093894-1|AAH93894.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 90.2 bits (214), Expect = 5e-18
Identities = 51/160 (31%), Positives = 86/160 (53%), Gaps = 3/160 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLC 397
E+ + I A+ F G +T+SS S+ L LA + E Q++ + EI EV+ R +L
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378
Query: 396 YDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+D + ++P TM KE+LR +P + + R CT +P+ G I G+ ++ ++
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPD-GRIIPKGIICLVSIYGTHHN 437
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
+ D + P RF D+ ++ +++PF AGPRNCIG
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIG 477
>BC069351-1|AAH69351.1| 531|Homo sapiens cytochrome P450, family 4,
subfamily F, polypeptide 22 protein.
Length = 531
Score = 90.2 bits (214), Expect = 5e-18
Identities = 51/160 (31%), Positives = 86/160 (53%), Gaps = 3/160 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLC 397
E+ + I A+ F G +T+SS S+ L LA + E Q++ + EI EV+ R +L
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378
Query: 396 YDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+D + ++P TM KE+LR +P + + R CT +P+ G I G+ ++ ++
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPD-GRIIPKGIICLVSIYGTHHN 437
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
+ D + P RF D+ ++ +++PF AGPRNCIG
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIG 477
>AK096820-1|BAC04868.1| 531|Homo sapiens protein ( Homo sapiens
cDNA FLJ39501 fis, clone PROST2016980, moderately
similar to CYTOCHROME P450 4F2 (EC 1.14.13.30). ).
Length = 531
Score = 90.2 bits (214), Expect = 5e-18
Identities = 51/160 (31%), Positives = 86/160 (53%), Gaps = 3/160 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS-RHDNKLC 397
E+ + I A+ F G +T+SS S+ L LA + E Q++ + EI EV+ R +L
Sbjct: 319 ELSDEDIRAEADTFMFEGHDTTSSGISWMLFNLAKYPEYQEKCREEIQEVMKGRELEELE 378
Query: 396 YDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+D + ++P TM KE+LR +P + + R CT +P+ G I G+ ++ ++
Sbjct: 379 WDDLTQLPFTTMCIKESLRQYPPVTLVSRQCTEDIKLPD-GRIIPKGIICLVSIYGTHHN 437
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
+ D + P RF D+ ++ +++PF AGPRNCIG
Sbjct: 438 PTVWPDSKVYNPYRFDPDNPQQRSPLAYVPFSAGPRNCIG 477
>AF525488-1|AAO16078.1| 519|Homo sapiens cytochrome P450, subfamily
IVA, polypeptide 11 protein.
Length = 519
Score = 90.2 bits (214), Expect = 5e-18
Identities = 49/156 (31%), Positives = 84/156 (53%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR+FP + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLFPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIG 103
+ +P F P RFA S +FLPF G RNCIG
Sbjct: 424 VWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIG 459
>AF233625-1|AAF99279.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.2 bits (214), Expect = 5e-18
Identities = 49/160 (30%), Positives = 84/160 (52%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHQPFTYLPFGAGPRSCLGVRLGLLE 489
>AF233622-1|AAF99276.1| 534|Homo sapiens thromboxane synthase
protein.
Length = 534
Score = 90.2 bits (214), Expect = 5e-18
Identities = 49/160 (30%), Positives = 83/160 (51%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 332 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 391
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + LG I G + + A+ +D +++ P
Sbjct: 392 PYLDMVIAETLRMYPPAFRFTREAAEDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 449
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G RLG ++
Sbjct: 450 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVRLGLLE 489
>AY280372-1|AAQ21368.1| 519|Homo sapiens cytochrome P450 4A22
protein.
Length = 519
Score = 89.8 bits (213), Expect = 7e-18
Identities = 49/163 (30%), Positives = 86/163 (52%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
+ +P F P RFA S +FLPF G RNCIG + Q
Sbjct: 424 VWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQ 466
>AY280371-1|AAQ21367.1| 519|Homo sapiens cytochrome P450 4A22K
protein.
Length = 519
Score = 89.4 bits (212), Expect = 1e-17
Identities = 49/163 (30%), Positives = 86/163 (52%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
+ +P F P RFA S +FLPF G RNCIG + Q
Sbjct: 424 VWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQ 466
>L04751-1|AAA58436.1| 519|Homo sapiens cytochrome P450 protein.
Length = 519
Score = 89.0 bits (211), Expect = 1e-17
Identities = 48/156 (30%), Positives = 84/156 (53%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIG 103
+ +P F P RFA S +FLPF G RNCIG
Sbjct: 424 VWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIG 459
>D26481-1|BAA05491.1| 519|Homo sapiens fatty acids
omega-hydroxylase protein.
Length = 519
Score = 89.0 bits (211), Expect = 1e-17
Identities = 48/156 (30%), Positives = 84/156 (53%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIG 103
+ +P F P RFA S +FLPF G RNCIG
Sbjct: 424 VWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIG 459
>D13705-1|BAA02864.1| 521|Homo sapiens fatty acid omega-hydroxylase
protein.
Length = 521
Score = 89.0 bits (211), Expect = 1e-17
Identities = 48/156 (30%), Positives = 84/156 (53%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 307 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 365
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 366 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 424
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIG 103
+ +P F P RFA S +FLPF G RNCIG
Sbjct: 425 VWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIG 460
>AY369778-1|AAQ56847.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 89.0 bits (211), Expect = 1e-17
Identities = 48/156 (30%), Positives = 84/156 (53%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIG 103
+ +P F P RFA S +FLPF G RNCIG
Sbjct: 424 VWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIG 459
>AL731892-3|CAH72778.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 519
Score = 89.0 bits (211), Expect = 1e-17
Identities = 48/156 (30%), Positives = 84/156 (53%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIG 103
+ +P F P RFA S +FLPF G RNCIG
Sbjct: 424 VWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSRNCIG 459
>D34625-1|BAA07011.1| 533|Homo sapiens thromboxane synthase
protein.
Length = 533
Score = 88.6 bits (210), Expect = 2e-17
Identities = 48/160 (30%), Positives = 83/160 (51%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
IV Q F+F AG+E ++ S+ + LA + + Q+++ E+D +H +
Sbjct: 331 IVGQAFIFLIAGYEIITNTLSFATYLLATNPDCQEKLLREVDVFKEKHMAPEFCSLEEGL 390
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P L M E LRM+P R + + LG I G + + A+ +D +++ P
Sbjct: 391 PYLDMVIAETLRMYPPAFRFTREAAQDCEV--LGQRIPAGAVLEMAVGALHHDPEHWPSP 448
Query: 195 SEFRPKRFAKDS--EIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+RF ++ + + F++LPFGAGPR+C+G LG ++
Sbjct: 449 ETFNPERFTAEARQQHRPFTYLPFGAGPRSCLGVHLGLLE 488
>AL135960-9|CAI19737.1| 519|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 22 protein.
Length = 519
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/163 (29%), Positives = 85/163 (52%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
+ + F P RFA S +FLPF G RNCIG + Q
Sbjct: 424 VWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQ 466
>AF208532-1|AAF76722.1| 519|Homo sapiens fatty acid
omega-hydroxylase CYP4A11 protein.
Length = 519
Score = 85.8 bits (203), Expect = 1e-16
Identities = 48/163 (29%), Positives = 85/163 (52%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
+ + F P RFA S +FLPF G RNCIG + Q
Sbjct: 424 VWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQ 466
>S67623-1|AAB29308.1| 257|Homo sapiens 25-hydroxyvitamin D
24-hydroxylase cytochrome P450 subunit protein.
Length = 257
Score = 83.8 bits (198), Expect = 5e-16
Identities = 49/167 (29%), Positives = 88/167 (52%), Gaps = 1/167 (0%)
Frame = -1
Query: 579 QPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKL 400
Q + K + A + A ET++++ + L+ L+ + ++Q+++ EI VL +
Sbjct: 51 QNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPR 110
Query: 399 CYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQN 220
D + MP L KE++R+ PS+ R ++ + E + G +++ Q + +
Sbjct: 111 AED-LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALP--KGTVLMLNTQVLGS 167
Query: 219 DAKYFDDPSEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEMQ 82
F+D S+FRP+R+ ++ E I F+ LPFG G R CIG RL E+Q
Sbjct: 168 SEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQ 214
>BC028102-1|AAH28102.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 83.8 bits (198), Expect = 5e-16
Identities = 42/151 (27%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
+++ F AG +T +++ S+ L+ LA + E Q+ + E+ +L + + +D + EM
Sbjct: 308 SEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILG-DGSSITWDQLGEMSY 366
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE R+ P++ ++ R ++ T P+ G T+ G+ +++ + ++ + +P
Sbjct: 367 TTMCIKETCRLIPAVPSISRDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKV 425
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F P RF++++ ++ +++LPF AG RNCIG
Sbjct: 426 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 456
>AY858838-1|AAW50795.1| 372|Homo sapiens vitamin D 24-hydroxylase
splice variant protein.
Length = 372
Score = 83.8 bits (198), Expect = 5e-16
Identities = 49/167 (29%), Positives = 88/167 (52%), Gaps = 1/167 (0%)
Frame = -1
Query: 579 QPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKL 400
Q + K + A + A ET++++ + L+ L+ + ++Q+++ EI VL +
Sbjct: 166 QNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPR 225
Query: 399 CYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQN 220
D + MP L KE++R+ PS+ R ++ + E + G +++ Q + +
Sbjct: 226 AED-LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALP--KGTVLMLNTQVLGS 282
Query: 219 DAKYFDDPSEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEMQ 82
F+D S+FRP+R+ ++ E I F+ LPFG G R CIG RL E+Q
Sbjct: 283 SEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQ 329
>AY358537-1|AAQ88901.1| 509|Homo sapiens EFSW1929 protein.
Length = 509
Score = 83.8 bits (198), Expect = 5e-16
Identities = 42/151 (27%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
+++ F AG +T +++ S+ L+ LA + E Q+ + E+ +L + + +D + EM
Sbjct: 308 SEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILG-DGSSITWDQLGEMSY 366
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE R+ P++ ++ R ++ T P+ G T+ G+ +++ + ++ + +P
Sbjct: 367 TTMCIKETCRLIPAVPSISRDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKV 425
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F P RF++++ ++ +++LPF AG RNCIG
Sbjct: 426 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 456
>AM040940-1|CAJ13826.1| 509|Homo sapiens cytochrome P450 protein.
Length = 509
Score = 83.8 bits (198), Expect = 5e-16
Identities = 42/151 (27%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
+++ F AG +T +++ S+ L+ LA + E Q+ + E+ +L + + +D + EM
Sbjct: 308 SEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILG-DGSSITWDQLGEMSY 366
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE R+ P++ ++ R ++ T P+ G T+ G+ +++ + ++ + +P
Sbjct: 367 TTMCIKETCRLIPAVPSISRDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKV 425
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F P RF++++ ++ +++LPF AG RNCIG
Sbjct: 426 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 456
>AL450996-1|CAH71035.1| 509|Homo sapiens cytochrome P450, family 4,
subfamily X, polypeptide 1 protein.
Length = 509
Score = 83.8 bits (198), Expect = 5e-16
Identities = 42/151 (27%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
+++ F AG +T +++ S+ L+ LA + E Q+ + E+ +L + + +D + EM
Sbjct: 308 SEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILG-DGSSITWDQLGEMSY 366
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE R+ P++ ++ R ++ T P+ G T+ G+ +++ + ++ + +P
Sbjct: 367 TTMCIKETCRLIPAVPSISRDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKV 425
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F P RF++++ ++ +++LPF AG RNCIG
Sbjct: 426 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 456
>AL138805-2|CAB91829.1| 514|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 514
Score = 83.8 bits (198), Expect = 5e-16
Identities = 49/167 (29%), Positives = 88/167 (52%), Gaps = 1/167 (0%)
Frame = -1
Query: 579 QPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKL 400
Q + K + A + A ET++++ + L+ L+ + ++Q+++ EI VL +
Sbjct: 308 QNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPR 367
Query: 399 CYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQN 220
D + MP L KE++R+ PS+ R ++ + E + G +++ Q + +
Sbjct: 368 AED-LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALP--KGTVLMLNTQVLGS 424
Query: 219 DAKYFDDPSEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEMQ 82
F+D S+FRP+R+ ++ E I F+ LPFG G R CIG RL E+Q
Sbjct: 425 SEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQ 471
>AL138805-1|CAM27342.1| 372|Homo sapiens cytochrome P450, family
24, subfamily A, polypeptide 1 protein.
Length = 372
Score = 83.8 bits (198), Expect = 5e-16
Identities = 49/167 (29%), Positives = 88/167 (52%), Gaps = 1/167 (0%)
Frame = -1
Query: 579 QPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKL 400
Q + K + A + A ET++++ + L+ L+ + ++Q+++ EI VL +
Sbjct: 166 QNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQVPR 225
Query: 399 CYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQN 220
D + MP L KE++R+ PS+ R ++ + E + G +++ Q + +
Sbjct: 226 AED-LRNMPYLKACLKESMRLTPSVPFTTRTLDKATVLGEYALP--KGTVLMLNTQVLGS 282
Query: 219 DAKYFDDPSEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEMQ 82
F+D S+FRP+R+ ++ E I F+ LPFG G R CIG RL E+Q
Sbjct: 283 SEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQ 329
>AK131355-1|BAD18508.1| 508|Homo sapiens protein ( Homo sapiens
cDNA FLJ16384 fis, clone TLIVE2007607, weakly similar
to CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 508
Score = 83.8 bits (198), Expect = 5e-16
Identities = 42/151 (27%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
+++ F AG +T +++ S+ L+ LA + E Q+ + E+ +L + + +D + EM
Sbjct: 307 SEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILG-DGSSITWDQLGEMSY 365
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE R+ P++ ++ R ++ T P+ G T+ G+ +++ + ++ + +P
Sbjct: 366 TTMCIKETCRLIPAVPSISRDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKV 424
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F P RF++++ ++ +++LPF AG RNCIG
Sbjct: 425 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 455
>AK098065-1|BAC05226.1| 509|Homo sapiens protein ( Homo sapiens
cDNA FLJ40746 fis, clone TRACH2000359, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 509
Score = 83.8 bits (198), Expect = 5e-16
Identities = 42/151 (27%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
+++ F AG +T +++ S+ L+ LA + E Q+ + E+ +L + + +D + EM
Sbjct: 308 SEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILG-DGSSITWDQLGEMSY 366
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE R+ P++ ++ R ++ T P+ G T+ G+ +++ + ++ + +P
Sbjct: 367 TTMCIKETCRLIPAVPSISRDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKV 425
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F P RF++++ ++ +++LPF AG RNCIG
Sbjct: 426 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 456
>AK091806-1|BAC03751.1| 444|Homo sapiens protein ( Homo sapiens
cDNA FLJ34487 fis, clone HLUNG2004273, weakly similar to
CYTOCHROME P450 4A4 (EC 1.14.14.1). ).
Length = 444
Score = 83.8 bits (198), Expect = 5e-16
Identities = 42/151 (27%), Positives = 87/151 (57%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
+++ F AG +T +++ S+ L+ LA + E Q+ + E+ +L + + +D + EM
Sbjct: 243 SEVSTFLLAGHDTLAASISWILYCLALNPEHQERCREEVRGILG-DGSSITWDQLGEMSY 301
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
TM KE R+ P++ ++ R ++ T P+ G T+ G+ +++ + ++ + +P
Sbjct: 302 TTMCIKETCRLIPAVPSISRDLSKPLTFPD-GCTLPAGITVVLSIWGLHHNPAVWKNPKV 360
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F P RF++++ ++ +++LPF AG RNCIG
Sbjct: 361 FDPLRFSQENSDQRHPYAYLPFSAGSRNCIG 391
>X71480-1|CAA50586.1| 141|Homo sapiens cytochrome P450 protein.
Length = 141
Score = 83.0 bits (196), Expect = 8e-16
Identities = 44/142 (30%), Positives = 76/142 (53%)
Frame = -1
Query: 534 FXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAF 355
F G +T++S S+ L+ LA H + Q+ + EI +L + ++ + +MP TM
Sbjct: 2 FMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLG-DGASITWNHLDQMPYTTMCI 60
Query: 354 KEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
KEALR++P + + R + T P+ G ++ G+ +++ + ++ K + +P F P R
Sbjct: 61 KEALRLYPPVPGISRELSTPVTFPD-GRSLPKGITVMLSIYGLHHNPKVWPNPEVFDPSR 119
Query: 174 FAKDSEIKKFSFLPFGAGPRNC 109
FA S +FLPF G RNC
Sbjct: 120 FAPGSAQHSHAFLPFSGGSRNC 141
>X16699-1|CAA34672.1| 511|Homo sapiens protein ( Human mRNA for
cytochrome P-450HP. ).
Length = 511
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 307 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 365
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 366 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 424
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 455
>J02871-1|AAA35712.1| 511|Homo sapiens protein ( Human lung
cytochrome P450 (IV subfamily) BI protein, complete cds.
).
Length = 511
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 307 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 365
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 366 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 424
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 455
>DQ518907-1|ABF47106.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 307 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 365
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 366 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 424
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 455
>BC017758-1|AAH17758.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 308 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 366
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 367 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 425
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 426 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 456
>AY151049-1|AAN72312.1| 497|Homo sapiens pulmonary cytochrome P450
4B1 variant protein.
Length = 497
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 293 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 351
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 352 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 410
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 411 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 441
>AY151048-1|AAN72311.1| 512|Homo sapiens pulmonary cytochrome P450
4B1 protein.
Length = 512
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 308 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 366
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 367 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 425
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 426 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 456
>AY064485-1|AAL57720.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 307 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 365
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 366 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 424
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 455
>AL593856-7|CAI16982.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 308 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 366
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 367 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 425
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 426 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 456
>AL593856-6|CAI16981.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 307 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 365
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 366 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 424
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 455
>AL593856-5|CAI16983.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 293 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 351
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 352 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 410
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 411 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 441
>AL356793-4|CAI22557.1| 512|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 512
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 308 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 366
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 367 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 425
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 426 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 456
>AL356793-3|CAI22559.1| 511|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 511
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 307 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 365
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 366 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 424
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 455
>AL356793-2|CAI22558.1| 497|Homo sapiens cytochrome P450, family 4,
subfamily B, polypeptide 1 protein.
Length = 497
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 293 AEVDTFMFEGHDTTTSGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 351
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 352 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 410
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 411 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 441
>AF491285-1|AAM09532.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 82.6 bits (195), Expect = 1e-15
Identities = 47/151 (31%), Positives = 84/151 (55%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++S S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 307 AEVDTFMFEGHDTTTSGISWFLYCIALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 365
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 366 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 424
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 455
>L13286-1|AAA62379.1| 513|Homo sapiens 1,25-dihydroxyvitamin D3
24-hydroxylase protein.
Length = 513
Score = 81.8 bits (193), Expect = 2e-15
Identities = 48/167 (28%), Positives = 87/167 (52%), Gaps = 1/167 (0%)
Frame = -1
Query: 579 QPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKL 400
Q + K + A + A ET++++ + L+ L+ + ++Q+++ EI VL +
Sbjct: 307 QNRLSKKELYAAVTELQLAAVETTANSLMWILYNLSRNPQVQQKLLKEIQSVLPENQRPR 366
Query: 399 CYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQN 220
D + MP L KE++R+ P + R ++ + E + G +++ Q + +
Sbjct: 367 EED-LRNMPYLKACLKESMRLTPGVPFTTRTLDKATVLGEYALP--KGTVLMLNTQVLGS 423
Query: 219 DAKYFDDPSEFRPKRFAKDSE-IKKFSFLPFGAGPRNCIGARLGEMQ 82
F+D S+FRP+R+ ++ E I F+ LPFG G R CIG RL E+Q
Sbjct: 424 SEDNFEDSSQFRPERWLQEKEKINPFAHLPFGVGKRMCIGRRLAELQ 470
>BC022539-1|AAH22539.1| 500|Homo sapiens cytochrome P450, family
46, subfamily A, polypeptide 1 protein.
Length = 500
Score = 81.4 bits (192), Expect = 3e-15
Identities = 43/162 (26%), Positives = 79/162 (48%)
Frame = -1
Query: 567 DTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDA 388
D + ++ F AG ETS++ ++T+ +L+ EI +Q E+DEV+ L ++
Sbjct: 288 DDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSK-RYLDFED 346
Query: 387 ILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKY 208
+ + L+ KE+LR++P R+ I G+ + ++ + Y
Sbjct: 347 LGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLID--GVRVPGNTPLLFSTYVMGRMDTY 404
Query: 207 FDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F+DP F P RF + +F++ PF G R+CIG + +M+
Sbjct: 405 FEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQME 446
>AF094480-1|AAD41244.1| 500|Homo sapiens cholesterol 24-hydroxylase
protein.
Length = 500
Score = 81.4 bits (192), Expect = 3e-15
Identities = 43/162 (26%), Positives = 79/162 (48%)
Frame = -1
Query: 567 DTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDA 388
D + ++ F AG ETS++ ++T+ +L+ EI +Q E+DEV+ L ++
Sbjct: 288 DDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIGSK-RYLDFED 346
Query: 387 ILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKY 208
+ + L+ KE+LR++P R+ I G+ + ++ + Y
Sbjct: 347 LGRLQYLSQVLKESLRLYPPAWGTFRLLEEETLID--GVRVPGNTPLLFSTYVMGRMDTY 404
Query: 207 FDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F+DP F P RF + +F++ PF G R+CIG + +M+
Sbjct: 405 FEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQME 446
>AY064486-1|AAL57721.1| 511|Homo sapiens cytochrome P450 protein.
Length = 511
Score = 81.0 bits (191), Expect = 3e-15
Identities = 46/151 (30%), Positives = 83/151 (54%), Gaps = 2/151 (1%)
Frame = -1
Query: 549 AQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPL 370
A++ F G +T++ S+ L+ +A + E Q + E+ E+L D +D + +M
Sbjct: 307 AEVDTFMFEGHDTTTGGISWFLYCMALYPEHQHRCREEVREILGDQDF-FQWDDLGKMTY 365
Query: 369 LTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSE 190
LTM KE+ R++P + ++R ++ T + G ++ G I + A+ ++ + DP
Sbjct: 366 LTMCIKESFRLYPPVPQVYRQLSKPVTFVD-GRSLPAGSLISMHIYALHRNSAVWPDPEV 424
Query: 189 FRPKRFAKDSEIKK--FSFLPFGAGPRNCIG 103
F RF+ ++ K+ F+F+PF AGPRNCIG
Sbjct: 425 FDSLRFSTENASKRHPFAFMPFSAGPRNCIG 455
>BC142607-1|AAI42608.1| 455|Homo sapiens CYP4A22 protein protein.
Length = 455
Score = 79.4 bits (187), Expect = 1e-14
Identities = 44/152 (28%), Positives = 80/152 (52%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPR 115
+ +P F P RFA S +FLPF G R
Sbjct: 424 VWPNPEVFDPSRFAPGSAQHSHAFLPFSGGSR 455
>BC041158-1|AAH41158.1| 455|Homo sapiens CYP4A11 protein protein.
Length = 455
Score = 79.0 bits (186), Expect = 1e-14
Identities = 44/152 (28%), Positives = 80/152 (52%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPR 115
+ +P F P RFA S +FLPF G R
Sbjct: 424 VWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSR 455
>AY288916-1|AAP31972.1| 508|Homo sapiens cytochrome P450, family
27, subfamily B, polypeptide 1 protein.
Length = 508
Score = 79.0 bits (186), Expect = 1e-14
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
E+ + I+ + AG +T S+ S+ L++L+ H E+Q + EI LS +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 393 DAIL-EMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L ++PLL KE LR++P + RV + + + I + + A D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDY--IIPKNTLVTLCHYATSRD 418
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
F +P+ FRP R+ + F+ LPFG G R+C+G RL E++
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELE 464
>AL731892-4|CAH72779.1| 455|Homo sapiens cytochrome P450, family 4,
subfamily A, polypeptide 11 protein.
Length = 455
Score = 79.0 bits (186), Expect = 1e-14
Identities = 44/152 (28%), Positives = 80/152 (52%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHSLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPR 115
+ +P F P RFA S +FLPF G R
Sbjct: 424 VWPNPEVFDPFRFAPGSAQHSHAFLPFSGGSR 455
>AF256213-1|AAG00416.1| 508|Homo sapiens 25- hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 79.0 bits (186), Expect = 1e-14
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
E+ + I+ + AG +T S+ S+ L++L+ H E+Q + EI LS +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 393 DAIL-EMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L ++PLL KE LR++P + RV + + + I + + A D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDY--IIPKNTLVTLCHYATSRD 418
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
F +P+ FRP R+ + F+ LPFG G R+C+G RL E++
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELE 464
>AF246895-1|AAF64299.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 79.0 bits (186), Expect = 1e-14
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
E+ + I+ + AG +T S+ S+ L++L+ H E+Q + EI LS +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 393 DAIL-EMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L ++PLL KE LR++P + RV + + + I + + A D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDY--IIPKNTLVTLCHYATSRD 418
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
F +P+ FRP R+ + F+ LPFG G R+C+G RL E++
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELE 464
>AF027152-1|AAC51854.1| 508|Homo sapiens P450 25-hydroxyvitamin D-1
alpha hydroxylase protein.
Length = 508
Score = 79.0 bits (186), Expect = 1e-14
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
E+ + I+ + AG +T S+ S+ L++L+ H E+Q + EI LS +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 393 DAIL-EMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L ++PLL KE LR++P + RV + + + I + + A D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDY--IIPKNTLVTLCHYATSRD 418
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
F +P+ FRP R+ + F+ LPFG G R+C+G RL E++
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELE 464
>AF020192-1|AAC51853.1| 508|Homo sapiens 25-hydroxyvitamin
D-1-alpha-hydroxylase protein.
Length = 508
Score = 79.0 bits (186), Expect = 1e-14
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
E+ + I+ + AG +T S+ S+ L++L+ H E+Q + EI LS +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 393 DAIL-EMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L ++PLL KE LR++P + RV + + + I + + A D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDY--IIPKNTLVTLCHYATSRD 418
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
F +P+ FRP R+ + F+ LPFG G R+C+G RL E++
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELE 464
>AB006987-1|BAA23418.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 79.0 bits (186), Expect = 1e-14
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
E+ + I+ + AG +T S+ S+ L++L+ H E+Q + EI LS +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 393 DAIL-EMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L ++PLL KE LR++P + RV + + + I + + A D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDY--IIPKNTLVTLCHYATSRD 418
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
F +P+ FRP R+ + F+ LPFG G R+C+G RL E++
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELE 464
>AB005990-1|BAA22657.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 79.0 bits (186), Expect = 1e-14
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
E+ + I+ + AG +T S+ S+ L++L+ H E+Q + EI LS +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 393 DAIL-EMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L ++PLL KE LR++P + RV + + + I + + A D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDY--IIPKNTLVTLCHYATSRD 418
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
F +P+ FRP R+ + F+ LPFG G R+C+G RL E++
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELE 464
>AB005989-1|BAA22656.1| 508|Homo sapiens 25-hydroxyvitamin D3
1alpha-hydroxylase protein.
Length = 508
Score = 79.0 bits (186), Expect = 1e-14
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
E+ + I+ + AG +T S+ S+ L++L+ H E+Q + EI LS +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 393 DAIL-EMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L ++PLL KE LR++P + RV + + + I + + A D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDY--IIPKNTLVTLCHYATSRD 418
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
F +P+ FRP R+ + F+ LPFG G R+C+G RL E++
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELE 464
>AB005038-1|BAA23416.1| 508|Homo sapiens 25-hydroxyvitamin D3
1-alpha-hydroxylase protein.
Length = 508
Score = 79.0 bits (186), Expect = 1e-14
Identities = 48/166 (28%), Positives = 81/166 (48%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
E+ + I+ + AG +T S+ S+ L++L+ H E+Q + EI LS +
Sbjct: 301 ELPAQSILGNVTELLLAGVDTVSNTLSWALYELSRHPEVQTALHSEITAALSPGSSAYPS 360
Query: 393 DAIL-EMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L ++PLL KE LR++P + RV + + + I + + A D
Sbjct: 361 ATVLSQLPLLKAVVKEVLRLYPVVPGNSRVPDKDIHVGDY--IIPKNTLVTLCHYATSRD 418
Query: 216 AKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
F +P+ FRP R+ + F+ LPFG G R+C+G RL E++
Sbjct: 419 PAQFPEPNSFRPARWLGEGPTPHPFASLPFGFGKRSCMGRRLAELE 464
>AK131190-1|BAD18388.1| 372|Homo sapiens .-.-). protein.
Length = 372
Score = 77.8 bits (183), Expect = 3e-14
Identities = 50/161 (31%), Positives = 80/161 (49%), Gaps = 3/161 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
I A + AG +T+S S+T++ LA H E+Q+ + EI + L D + ++
Sbjct: 170 IYANVTEMLLAGVDTTSFTLSWTVYLLARHPEVQQTVYREIVKNLGERHVPTAAD-VPKV 228
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
PL+ KE LR+FP L RV I G I G ++ + A + F
Sbjct: 229 PLVRALLKETLRLFPVLPGNGRVTQEDLVIG--GYLIPKGTQLALCHYATSYQDENFPRA 286
Query: 195 SEFRPKRFAKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
EFRP+R+ + ++ + F +PFG G R+CIG R+ E++
Sbjct: 287 KEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELE 327
>BC039307-1|AAH39307.1| 372|Homo sapiens cytochrome P450, family
27, subfamily C, polypeptide 1 protein.
Length = 372
Score = 77.4 bits (182), Expect = 4e-14
Identities = 50/161 (31%), Positives = 80/161 (49%), Gaps = 3/161 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
I A + AG +T+S S+T++ LA H E+Q+ + EI + L D + ++
Sbjct: 170 IYANVTEMLLAGVDTTSFTLSWTVYILARHPEVQQTVYREIVKNLGERHVPTAAD-VPKV 228
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
PL+ KE LR+FP L RV I G I G ++ + A + F
Sbjct: 229 PLVRALLKETLRLFPVLPGNGRVTQEDLVIG--GYLIPKGTQLALCHYATSYQDENFPRA 286
Query: 195 SEFRPKRFAKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
EFRP+R+ + ++ + F +PFG G R+CIG R+ E++
Sbjct: 287 KEFRPERWLRKGDLDRVDNFGSIPFGHGVRSCIGRRIAELE 327
>AL135960-11|CAI19738.1| 455|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 455
Score = 75.4 bits (177), Expect = 2e-13
Identities = 43/152 (28%), Positives = 79/152 (51%)
Frame = -1
Query: 570 MDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYD 391
+ K + A++ F G +T++S S+ L+ LA H + Q+ + EI +L + ++
Sbjct: 306 LSDKDLRAEVDTFMFEGHDTTASGISWILYALATHPKHQERCREEIHGLLG-DGASITWN 364
Query: 390 AILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAK 211
+ +MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K
Sbjct: 365 HLDQMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPK 423
Query: 210 YFDDPSEFRPKRFAKDSEIKKFSFLPFGAGPR 115
+ + F P RFA S +FLPF G R
Sbjct: 424 VWPNLEVFDPSRFAPGSAQHSHAFLPFSGGSR 455
>U23942-1|AAB39951.1| 509|Homo sapiens lanosterol 14-demethylase
cytochrome P450 protein.
Length = 509
Score = 71.3 bits (167), Expect = 3e-12
Identities = 51/190 (26%), Positives = 89/190 (46%), Gaps = 2/190 (1%)
Frame = -1
Query: 645 RKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFH 466
R+ K + I + +D T +P D + + + AG TSS+ +++ LA
Sbjct: 278 RQSQEKIDDILQTLLDATYKDGRPLTDDE-VAGMLIGLLLAGQHTSSTTSAWMGFFLARD 336
Query: 465 QEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTI 286
+ +QK+ E V + L YD + ++ LL KE LR+ P + + R+ T+
Sbjct: 337 KTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTV 396
Query: 285 PELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEI--KKFSFLPFGAGPRN 112
G TI PG ++ + Q + + +F P R+ +D+ +KF+++PFGAG
Sbjct: 397 --AGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHR 454
Query: 111 CIGARLGEMQ 82
CIG +Q
Sbjct: 455 CIGENFAYVQ 464
>D55653-1|BAA09512.1| 509|Homo sapiens lanosterol 14-demethylase
protein.
Length = 509
Score = 71.3 bits (167), Expect = 3e-12
Identities = 51/190 (26%), Positives = 89/190 (46%), Gaps = 2/190 (1%)
Frame = -1
Query: 645 RKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFH 466
R+ K + I + +D T +P D + + + AG TSS+ +++ LA
Sbjct: 278 RQSQEKIDDILQTLLDATYKDGRPLTDDE-VAGMLIGLLLAGQHTSSTTSAWMGFFLARD 336
Query: 465 QEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTI 286
+ +QK+ E V + L YD + ++ LL KE LR+ P + + R+ T+
Sbjct: 337 KTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTV 396
Query: 285 PELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEI--KKFSFLPFGAGPRN 112
G TI PG ++ + Q + + +F P R+ +D+ +KF+++PFGAG
Sbjct: 397 --AGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHR 454
Query: 111 CIGARLGEMQ 82
CIG +Q
Sbjct: 455 CIGENFAYVQ 464
>AC000120-2|AAB46356.1| 509|Homo sapiens unknown protein.
Length = 509
Score = 71.3 bits (167), Expect = 3e-12
Identities = 51/190 (26%), Positives = 89/190 (46%), Gaps = 2/190 (1%)
Frame = -1
Query: 645 RKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFH 466
R+ K + I + +D T +P D + + + AG TSS+ +++ LA
Sbjct: 278 RQSQEKIDDILQTLLDATYKDGRPLTDDE-VAGMLIGLLLAGQHTSSTTSAWMGFFLARD 336
Query: 465 QEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTI 286
+ +QK+ E V + L YD + ++ LL KE LR+ P + + R+ T+
Sbjct: 337 KTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPIMIMMRMARTPQTV 396
Query: 285 PELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEI--KKFSFLPFGAGPRN 112
G TI PG ++ + Q + + +F P R+ +D+ +KF+++PFGAG
Sbjct: 397 --AGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHR 454
Query: 111 CIGARLGEMQ 82
CIG +Q
Sbjct: 455 CIGENFAYVQ 464
>BC032322-1|AAH32322.1| 509|Homo sapiens cytochrome P450, family
51, subfamily A, polypeptide 1 protein.
Length = 509
Score = 70.9 bits (166), Expect = 4e-12
Identities = 51/190 (26%), Positives = 89/190 (46%), Gaps = 2/190 (1%)
Frame = -1
Query: 645 RKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFH 466
R+ K + I + +D T +P D + + + AG TSS+ +++ LA
Sbjct: 278 RQSQEKIDDILQTLLDATYKDGRPLTDDE-VAGMLIGLLLAGQHTSSTTSAWMGFFLARD 336
Query: 465 QEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTI 286
+ +QK+ E V + L YD + ++ LL KE LR+ P + + R+ T+
Sbjct: 337 KTLQKKCYLEQKTVCGENLPPLTYDQLKDLNLLDRCIKETLRLRPPVMIMMRMARTPQTV 396
Query: 285 PELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEI--KKFSFLPFGAGPRN 112
G TI PG ++ + Q + + +F P R+ +D+ +KF+++PFGAG
Sbjct: 397 --AGYTIPPGHQVCVSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHR 454
Query: 111 CIGARLGEMQ 82
CIG +Q
Sbjct: 455 CIGENFAYVQ 464
>AK090886-1|BAC03539.1| 337|Homo sapiens protein ( Homo sapiens
cDNA FLJ33567 fis, clone BRAMY2010272, highly similar to
Homo sapiens cholesterol 24-hydroxylase mRNA. ).
Length = 337
Score = 70.5 bits (165), Expect = 5e-12
Identities = 43/162 (26%), Positives = 77/162 (47%)
Frame = -1
Query: 567 DTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDA 388
D + ++ F AG ETS++ ++T+ +L+ EI +Q E+DEV+ L ++
Sbjct: 135 DDEGLLDNFVTFFIAGHETSANHLAFTVMELSRQPEIVARLQAEVDEVIG-SKRYLDFED 193
Query: 387 ILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKY 208
+ + L+ KE+LR++P R+ T+ G + + Y
Sbjct: 194 LGRLQYLSQVLKESLRLYPPAWGTFRLLEEE--------TLIDGFSTYVMGRM----DTY 241
Query: 207 FDDPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F+DP F P RF + +F++ PF G R+CIG + +M+
Sbjct: 242 FEDPLTFNPDRFGPGAPKPRFTYFPFSLGHRSCIGQQFAQME 283
>X05367-1|CAA28965.1| 521|Homo sapiens desmolase protein.
Length = 521
Score = 70.1 bits (164), Expect = 6e-12
Identities = 47/166 (28%), Positives = 83/166 (50%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
+M + I A + A G +T+S + L+++A + ++Q ++ E+ + +RH +
Sbjct: 310 KMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEV--LAARHQAQGDM 367
Query: 393 DAILEM-PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L++ PLL + KE LR+ P L R + + I V++ I A+ +
Sbjct: 368 ATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAI--YALGRE 425
Query: 216 AKYFDDPSEFRPKRF-AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
+F DP F P R+ +KD I F L FG G R C+G R+ E++
Sbjct: 426 PTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELE 471
>M28253-1|AAA36404.1| 239|Homo sapiens cytochrome P-450-scc
protein.
Length = 239
Score = 70.1 bits (164), Expect = 6e-12
Identities = 47/166 (28%), Positives = 83/166 (50%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
+M + I A + A G +T+S + L+++A + ++Q ++ E+ + +RH +
Sbjct: 28 KMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEV--LAARHQAQGDM 85
Query: 393 DAILEM-PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L++ PLL + KE LR+ P L R + + I V++ I A+ +
Sbjct: 86 ATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAI--YALGRE 143
Query: 216 AKYFDDPSEFRPKRF-AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
+F DP F P R+ +KD I F L FG G R C+G R+ E++
Sbjct: 144 PTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELE 189
>M14565-1|AAA52162.1| 521|Homo sapiens CYP11A protein.
Length = 521
Score = 70.1 bits (164), Expect = 6e-12
Identities = 47/166 (28%), Positives = 83/166 (50%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
+M + I A + A G +T+S + L+++A + ++Q ++ E+ + +RH +
Sbjct: 310 KMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEV--LAARHQAQGDM 367
Query: 393 DAILEM-PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L++ PLL + KE LR+ P L R + + I V++ I A+ +
Sbjct: 368 ATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAI--YALGRE 425
Query: 216 AKYFDDPSEFRPKRF-AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
+F DP F P R+ +KD I F L FG G R C+G R+ E++
Sbjct: 426 PTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELE 471
>BC032329-1|AAH32329.1| 521|Homo sapiens cytochrome P450, family
11, subfamily A, polypeptide 1 protein.
Length = 521
Score = 70.1 bits (164), Expect = 6e-12
Identities = 47/166 (28%), Positives = 83/166 (50%), Gaps = 2/166 (1%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCY 394
+M + I A + A G +T+S + L+++A + ++Q ++ E+ + +RH +
Sbjct: 310 KMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEV--LAARHQAQGDM 367
Query: 393 DAILEM-PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQND 217
+L++ PLL + KE LR+ P L R + + I V++ I A+ +
Sbjct: 368 ATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAI--YALGRE 425
Query: 216 AKYFDDPSEFRPKRF-AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
+F DP F P R+ +KD I F L FG G R C+G R+ E++
Sbjct: 426 PTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELE 471
>U51692-1|AAC50951.1| 503|Homo sapiens lanosterol 14-alpha
demethylase protein.
Length = 503
Score = 69.3 bits (162), Expect = 1e-11
Identities = 47/176 (26%), Positives = 83/176 (47%), Gaps = 2/176 (1%)
Frame = -1
Query: 603 VDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEV 424
+D T +P D + + + AG TSS+ +++ LA + +QK+ E V
Sbjct: 286 LDATYKDGRPLTDDE-VAGMLIGLLLAGQHTSSTTSAWMGFFLARDKTLQKKCYLEQKTV 344
Query: 423 LSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRII 244
+ L YD + ++ LL +E LR+ P + + R+ T+ G TI PG ++
Sbjct: 345 CGENLPPLTYDQLKDLNLLDRCIRETLRLRPPIMIMMRMARTPQTV--AGYTIPPGHQVC 402
Query: 243 IPAQAIQNDAKYFDDPSEFRPKRFAKDSEI--KKFSFLPFGAGPRNCIGARLGEMQ 82
+ Q + + +F P R+ +D+ +KF+++PFGAG CIG +Q
Sbjct: 403 VSPTVNQRLKDSWVERLDFNPDRYLQDNPASGEKFAYVPFGAGRHRCIGENFAYVQ 458
>X08006-1|CAA30807.1| 497|Homo sapiens cytochrome P450 db1 protein.
Length = 497
Score = 68.9 bits (161), Expect = 1e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>M20403-1|AAA52153.1| 497|Homo sapiens CYP2D protein.
Length = 497
Score = 68.9 bits (161), Expect = 1e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGMTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>M33388-1|AAA53500.1| 497|Homo sapiens cytochrome P450 IID6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>M33189-1|AAA35737.1| 500|Homo sapiens protein ( Human debrisoquine
4-hydroxylase mutant allele (CYP2D6-MA1) gene, complete
cds. ).
Length = 500
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 287 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 343
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 344 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 401
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 402 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 455
>M24499-1|AAA36403.1| 373|Homo sapiens cytochrome P450db1 protein.
Length = 373
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 160 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 216
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 217 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 274
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 275 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 328
>DQ282154-1|ABB77902.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ282152-1|ABB77900.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ282151-1|ABB77899.1| 496|Homo sapiens cytochrome P450 2D6
protein.
Length = 496
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 283 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 339
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 340 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 397
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 398 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 451
>DQ282146-1|ABB77897.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ282145-1|ABB77896.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ282144-1|ABB77895.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ211354-2|ABB01372.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ211353-2|ABB01371.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ211353-1|ABB01370.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>BC075024-1|AAH75024.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>BC075023-1|AAH75023.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>AY545216-1|AAS55001.1| 497|Homo sapiens cytochrome P4502D6
protein.
Length = 497
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 284 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 340
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 341 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 398
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 399 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>AL135960-10|CAI19736.1| 421|Homo sapiens cytochrome P450, family
4, subfamily A, polypeptide 22 protein.
Length = 421
Score = 68.1 bits (159), Expect = 3e-11
Identities = 33/100 (33%), Positives = 53/100 (53%)
Frame = -1
Query: 381 EMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFD 202
+MP TM KEALR++P + + R + T P+ G ++ G+ +++ + ++ K +
Sbjct: 270 QMPYTTMCIKEALRLYPPVPGIGRELSTPVTFPD-GRSLPKGIMVLLSIYGLHHNPKVWP 328
Query: 201 DPSEFRPKRFAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
+ F P RFA S +FLPF G RNCIG + Q
Sbjct: 329 NLEVFDPSRFAPGSAQHSHAFLPFSGGSRNCIGKQFAMNQ 368
>AB209492-1|BAD92729.1| 566|Homo sapiens Debrisoquine 4-hydroxylase
mutant allele variant protein.
Length = 566
Score = 68.1 bits (159), Expect = 3e-11
Identities = 49/174 (28%), Positives = 79/174 (45%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P + + + +VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+
Sbjct: 353 GNPESSFNDENLRIVVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIG 409
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIP 238
+ D MP T E R F + L S I G I G +I
Sbjct: 410 QVRRPEMGDQA-HMPYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITN 467
Query: 237 AQAIQNDAKYFDDPSEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
++ D ++ P F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 468 LSSVLKDEAVWEKPFRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 521
>M63871-1|AAA59984.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/195 (27%), Positives = 90/195 (46%), Gaps = 6/195 (3%)
Frame = -1
Query: 648 NRKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAF 469
N +L ++ N + P Q + I+ + AG ET++S +TL L
Sbjct: 261 NMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLH 320
Query: 468 HQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNL--HRVCTRS 295
+ +++K++ EID+ + D + LL +E LR+ P L H+ S
Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDS 379
Query: 294 YTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEIK----KFSFLPFG 127
+I E + D G +II A+ ++ K + P +F P+RF + + S+LPFG
Sbjct: 380 -SIGEFAV--DKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFG 436
Query: 126 AGPRNCIGARLGEMQ 82
AGPR+CIG L +
Sbjct: 437 AGPRSCIGEILARQE 451
>M31153-1|AAA52140.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/195 (27%), Positives = 90/195 (46%), Gaps = 6/195 (3%)
Frame = -1
Query: 648 NRKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAF 469
N +L ++ N + P Q + I+ + AG ET++S +TL L
Sbjct: 261 NMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLH 320
Query: 468 HQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNL--HRVCTRS 295
+ +++K++ EID+ + D + LL +E LR+ P L H+ S
Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDS 379
Query: 294 YTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEIK----KFSFLPFG 127
+I E + D G +II A+ ++ K + P +F P+RF + + S+LPFG
Sbjct: 380 -SIGEFAV--DKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFG 436
Query: 126 AGPRNCIGARLGEMQ 82
AGPR+CIG L +
Sbjct: 437 AGPRSCIGEILARQE 451
>M19489-1|AAA36405.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/195 (27%), Positives = 90/195 (46%), Gaps = 6/195 (3%)
Frame = -1
Query: 648 NRKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAF 469
N +L ++ N + P Q + I+ + AG ET++S +TL L
Sbjct: 261 NMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLH 320
Query: 468 HQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNL--HRVCTRS 295
+ +++K++ EID+ + D + LL +E LR+ P L H+ S
Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDS 379
Query: 294 YTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEIK----KFSFLPFG 127
+I E + D G +II A+ ++ K + P +F P+RF + + S+LPFG
Sbjct: 380 -SIGEFAV--DKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFG 436
Query: 126 AGPRNCIGARLGEMQ 82
AGPR+CIG L +
Sbjct: 437 AGPRSCIGEILARQE 451
>M14564-1|AAA52151.1| 508|Homo sapiens CYP17 protein.
Length = 508
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/195 (27%), Positives = 90/195 (46%), Gaps = 6/195 (3%)
Frame = -1
Query: 648 NRKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAF 469
N +L ++ N + P Q + I+ + AG ET++S +TL L
Sbjct: 261 NMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLH 320
Query: 468 HQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNL--HRVCTRS 295
+ +++K++ EID+ + D + LL +E LR+ P L H+ S
Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDS 379
Query: 294 YTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEIK----KFSFLPFG 127
+I E + D G +II A+ ++ K + P +F P+RF + + S+LPFG
Sbjct: 380 -SIGEFAV--DKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFG 436
Query: 126 AGPRNCIGARLGEMQ 82
AGPR+CIG L +
Sbjct: 437 AGPRSCIGEILARQE 451
>DQ530598-1|ABF50972.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/195 (27%), Positives = 90/195 (46%), Gaps = 6/195 (3%)
Frame = -1
Query: 648 NRKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAF 469
N +L ++ N + P Q + I+ + AG ET++S +TL L
Sbjct: 261 NMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLH 320
Query: 468 HQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNL--HRVCTRS 295
+ +++K++ EID+ + D + LL +E LR+ P L H+ S
Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDS 379
Query: 294 YTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEIK----KFSFLPFG 127
+I E + D G +II A+ ++ K + P +F P+RF + + S+LPFG
Sbjct: 380 -SIGEFAV--DKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFG 436
Query: 126 AGPRNCIGARLGEMQ 82
AGPR+CIG L +
Sbjct: 437 AGPRSCIGEILARQE 451
>BT020000-1|AAV38803.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/195 (27%), Positives = 90/195 (46%), Gaps = 6/195 (3%)
Frame = -1
Query: 648 NRKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAF 469
N +L ++ N + P Q + I+ + AG ET++S +TL L
Sbjct: 261 NMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLH 320
Query: 468 HQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNL--HRVCTRS 295
+ +++K++ EID+ + D + LL +E LR+ P L H+ S
Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDS 379
Query: 294 YTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEIK----KFSFLPFG 127
+I E + D G +II A+ ++ K + P +F P+RF + + S+LPFG
Sbjct: 380 -SIGEFAV--DKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFG 436
Query: 126 AGPRNCIGARLGEMQ 82
AGPR+CIG L +
Sbjct: 437 AGPRSCIGEILARQE 451
>BC104909-1|AAI04910.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 67.7 bits (158), Expect = 3e-11
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AG ET+++ + + +A + IQ ++Q EID ++ + K +D +MP E
Sbjct: 310 AGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPN-GKPSWDDKCKMPYTEAVLHEV 368
Query: 345 LRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAK 166
LR F ++ L S G +I G +I ++ D KY+ DP F P+RF
Sbjct: 369 LR-FCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLD 427
Query: 165 DSE--IKKFSFLPFGAGPRNCIGARLGEMQ 82
S KK + +PF G R+C+G L M+
Sbjct: 428 SSGYFAKKEALVPFSLGRRHCLGEHLARME 457
>BC104907-1|AAI04908.1| 501|Homo sapiens cytochrome P450, family 2,
subfamily R, polypeptide 1 protein.
Length = 501
Score = 67.7 bits (158), Expect = 3e-11
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AG ET+++ + + +A + IQ ++Q EID ++ + K +D +MP E
Sbjct: 310 AGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPN-GKPSWDDKCKMPYTEAVLHEV 368
Query: 345 LRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAK 166
LR F ++ L S G +I G +I ++ D KY+ DP F P+RF
Sbjct: 369 LR-FCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLD 427
Query: 165 DSE--IKKFSFLPFGAGPRNCIGARLGEMQ 82
S KK + +PF G R+C+G L M+
Sbjct: 428 SSGYFAKKEALVPFSLGRRHCLGEHLARME 457
>BC063388-1|AAH63388.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/195 (27%), Positives = 90/195 (46%), Gaps = 6/195 (3%)
Frame = -1
Query: 648 NRKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAF 469
N +L ++ N + P Q + I+ + AG ET++S +TL L
Sbjct: 261 NMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLH 320
Query: 468 HQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNL--HRVCTRS 295
+ +++K++ EID+ + D + LL +E LR+ P L H+ S
Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDS 379
Query: 294 YTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEIK----KFSFLPFG 127
+I E + D G +II A+ ++ K + P +F P+RF + + S+LPFG
Sbjct: 380 -SIGEFAV--DKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFG 436
Query: 126 AGPRNCIGARLGEMQ 82
AGPR+CIG L +
Sbjct: 437 AGPRSCIGEILARQE 451
>BC062997-1|AAH62997.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/195 (27%), Positives = 90/195 (46%), Gaps = 6/195 (3%)
Frame = -1
Query: 648 NRKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAF 469
N +L ++ N + P Q + I+ + AG ET++S +TL L
Sbjct: 261 NMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLH 320
Query: 468 HQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNL--HRVCTRS 295
+ +++K++ EID+ + D + LL +E LR+ P L H+ S
Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDS 379
Query: 294 YTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEIK----KFSFLPFG 127
+I E + D G +II A+ ++ K + P +F P+RF + + S+LPFG
Sbjct: 380 -SIGEFAV--DKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFG 436
Query: 126 AGPRNCIGARLGEMQ 82
AGPR+CIG L +
Sbjct: 437 AGPRSCIGEILARQE 451
>AY323817-1|AAQ23114.1| 501|Homo sapiens cytochrome P450 2R1
protein.
Length = 501
Score = 67.7 bits (158), Expect = 3e-11
Identities = 45/150 (30%), Positives = 72/150 (48%), Gaps = 2/150 (1%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AG ET+++ + + +A + IQ ++Q EID ++ + K +D +MP E
Sbjct: 310 AGTETTTNVLRWAILFMALYPNIQGQVQKEIDLIMGPN-GKPSWDDKCKMPYTEAVLHEV 368
Query: 345 LRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAK 166
LR F ++ L S G +I G +I ++ D KY+ DP F P+RF
Sbjct: 369 LR-FCNIVPLGIFHATSEDAVVRGYSIPKGTTVITNLYSVHFDEKYWRDPEVFHPERFLD 427
Query: 165 DSE--IKKFSFLPFGAGPRNCIGARLGEMQ 82
S KK + +PF G R+C+G L M+
Sbjct: 428 SSGYFAKKEALVPFSLGRRHCLGEHLARME 457
>AL358790-3|CAI52498.1| 508|Homo sapiens cytochrome P450, family
17, subfamily A, polypeptide 1 protein.
Length = 508
Score = 67.7 bits (158), Expect = 3e-11
Identities = 54/195 (27%), Positives = 90/195 (46%), Gaps = 6/195 (3%)
Frame = -1
Query: 648 NRKGSLKGESIDRFNVDGTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAF 469
N +L ++ N + P Q + I+ + AG ET++S +TL L
Sbjct: 261 NMLDTLMQAKMNSDNGNAGPDQDSELLSDNHILTTIGDIFGAGVETTTSVVKWTLAFLLH 320
Query: 468 HQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEALRMFPSLGNL--HRVCTRS 295
+ +++K++ EID+ + D + LL +E LR+ P L H+ S
Sbjct: 321 NPQVKKKLYEEIDQNVGFSRTPTISDRN-RLLLLEATIREVLRLRPVAPMLIPHKANVDS 379
Query: 294 YTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAKDSEIK----KFSFLPFG 127
+I E + D G +II A+ ++ K + P +F P+RF + + S+LPFG
Sbjct: 380 -SIGEFAV--DKGTEVIINLWALHHNEKEWHQPDQFMPERFLNPAGTQLISPSVSYLPFG 436
Query: 126 AGPRNCIGARLGEMQ 82
AGPR+CIG L +
Sbjct: 437 AGPRSCIGEILARQE 451
>BC106758-1|AAI06759.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 67.3 bits (157), Expect = 4e-11
Identities = 48/160 (30%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EIDEV+ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDEVIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>BC067429-1|AAH67429.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 66.5 bits (155), Expect = 8e-11
Identities = 50/154 (32%), Positives = 75/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R P L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSPFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>DQ282162-1|ABB77909.1| 500|Homo sapiens cytochrome P450 2D6
protein.
Length = 500
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 301 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 356
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 357 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 415
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 416 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 455
>DQ282160-1|ABB77908.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ282159-1|ABB77907.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ282158-1|ABB77906.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ282157-1|ABB77905.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ282156-1|ABB77904.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ282155-1|ABB77903.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>DQ282147-1|ABB77898.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>CR456430-1|CAG30316.1| 446|Homo sapiens CYP2D6 protein.
Length = 446
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 247 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 302
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 303 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 361
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 362 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 401
>BC126858-1|AAI26859.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>BC106757-1|AAI06758.1| 446|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 446
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 247 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 302
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 303 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 361
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 362 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 401
>BC067432-1|AAH67432.1| 497|Homo sapiens cytochrome P450, family 2,
subfamily D, polypeptide 6 protein.
Length = 497
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>BC066877-1|AAH66877.1| 446|Homo sapiens CYP2D6 protein protein.
Length = 446
Score = 66.1 bits (154), Expect = 1e-10
Identities = 47/160 (29%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+V+ + D M
Sbjct: 247 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDVIGQVRRPEMGDQA-HM 302
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 303 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 361
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 362 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 401
>U37143-1|AAC50370.2| 502|Homo sapiens cytochrome P450
monooxygenase CYP2J2 protein.
Length = 502
Score = 65.3 bits (152), Expect = 2e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P E + C +F AG ET+S+ + L +A + EIQ+++Q EID V+
Sbjct: 290 GNPTSSFHEENLICSTLDLFF---AGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIG 346
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIII 241
+ + A MP E RM + N+ R T T+ G + G I+
Sbjct: 347 Q-GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTL--AGYHLPKGTMILT 403
Query: 240 PAQAIQNDAKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
A+ D + P F P F ++ + KK +F+PF G R C+G +L +
Sbjct: 404 NLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTE 457
>BC032594-1|AAH32594.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 65.3 bits (152), Expect = 2e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P E + C +F AG ET+S+ + L +A + EIQ+++Q EID V+
Sbjct: 290 GNPTSSFHEENLICSTLDLFF---AGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIG 346
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIII 241
+ + A MP E RM + N+ R T T+ G + G I+
Sbjct: 347 Q-GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTL--AGYHLPKGTMILT 403
Query: 240 PAQAIQNDAKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
A+ D + P F P F ++ + KK +F+PF G R C+G +L +
Sbjct: 404 NLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTE 457
>AY426985-1|AAQ93356.1| 502|Homo sapiens cytochrome P450, family 2,
subfamily J, polypeptide 2 protein.
Length = 502
Score = 65.3 bits (152), Expect = 2e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P E + C +F AG ET+S+ + L +A + EIQ+++Q EID V+
Sbjct: 290 GNPTSSFHEENLICSTLDLFF---AGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIG 346
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIII 241
+ + A MP E RM + N+ R T T+ G + G I+
Sbjct: 347 Q-GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTL--AGYHLPKGTMILT 403
Query: 240 PAQAIQNDAKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
A+ D + P F P F ++ + KK +F+PF G R C+G +L +
Sbjct: 404 NLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTE 457
>AY178622-1|AAO21126.1| 531|Homo sapiens steroid hydroxylase
protein.
Length = 531
Score = 65.3 bits (152), Expect = 2e-10
Identities = 41/154 (26%), Positives = 71/154 (46%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AG +T+S+ ++ L+ L+ EIQK + E+ V+ D MPLL KE
Sbjct: 335 AGVDTTSNTLTWALYHLSKDPEIQKALHEEVVGVVPAGQVPQHKD-FAHMPLLKAVLKET 393
Query: 345 LRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAK 166
LR++P + R+ + + G + + + D F +P F+P R+ +
Sbjct: 394 LRLYPVVPTNSRIIEKEIEVD--GFLFPKNTQFVFCHYEVSRDPTAFSEPESFQPHRWLR 451
Query: 165 DSEIKK------FSFLPFGAGPRNCIGARLGEMQ 82
+S+ F +PFG G R C+G R+ E++
Sbjct: 452 NSQPATPRIQHPFGSVPFGYGVRACLGRRIAELE 485
>AF272142-1|AAM44456.1| 502|Homo sapiens cytochrome P450 protein.
Length = 502
Score = 65.3 bits (152), Expect = 2e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P E + C +F AG ET+S+ + L +A + EIQ+++Q EID V+
Sbjct: 290 GNPTSSFHEENLICSTLDLFF---AGTETTSTTLRWALLYMALYPEIQEKVQAEIDRVIG 346
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIII 241
+ + A MP E RM + N+ R T T+ G + G I+
Sbjct: 347 Q-GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTL--AGYHLPKGTMILT 403
Query: 240 PAQAIQNDAKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
A+ D + P F P F ++ + KK +F+PF G R C+G +L +
Sbjct: 404 NLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTE 457
>Y00498-1|CAA68550.1| 490|Homo sapiens IIC2 protein.
Length = 490
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/166 (34%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = -1
Query: 552 VAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMP 373
VA +FV AG ET+S+ Y L L H E+ ++Q EID V+ RH + C MP
Sbjct: 291 VADLFV---AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP-CMQDRSHMP 346
Query: 372 LLTMAFKEALR---MFPSLGNLHRVCT----RSYTIPELGITIDPGVRIIIPAQAIQNDA 214
E R + P+ G H V T R+Y IP+ G I+ ++ +D
Sbjct: 347 YTDAVVHEIQRYSDLVPT-GVPHAVTTDTKFRNYLIPK-------GTTIMALLTSVLHDD 398
Query: 213 KYFDDPSEFRPKRFA-KDSEIKKFS-FLPFGAGPRNCIGARLGEMQ 82
K F +P+ F P F K+ KK F+PF AG R C G L M+
Sbjct: 399 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 444
>M21942-1|AAA52161.1| 462|Homo sapiens CYP2C protein.
Length = 462
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/166 (34%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = -1
Query: 552 VAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMP 373
VA +FV AG ET+S+ Y L L H E+ ++Q EID V+ RH + C MP
Sbjct: 263 VADLFV---AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP-CMQDRSHMP 318
Query: 372 LLTMAFKEALR---MFPSLGNLHRVCT----RSYTIPELGITIDPGVRIIIPAQAIQNDA 214
E R + P+ G H V T R+Y IP+ G I+ ++ +D
Sbjct: 319 YTDAVVHEIQRYSDLVPT-GVPHAVTTDTKFRNYLIPK-------GTTIMALLTSVLHDD 370
Query: 213 KYFDDPSEFRPKRFA-KDSEIKKFS-FLPFGAGPRNCIGARLGEMQ 82
K F +P+ F P F K+ KK F+PF AG R C G L M+
Sbjct: 371 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 416
>M17397-1|AAA35739.1| 490|Homo sapiens protein ( Human cytochrome
P-450 1 functional form mRNA, complete cds. ).
Length = 490
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/166 (34%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = -1
Query: 552 VAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMP 373
VA +FV AG ET+S+ Y L L H E+ ++Q EID V+ RH + C MP
Sbjct: 291 VADLFV---AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP-CMQDRSHMP 346
Query: 372 LLTMAFKEALR---MFPSLGNLHRVCT----RSYTIPELGITIDPGVRIIIPAQAIQNDA 214
E R + P+ G H V T R+Y IP+ G I+ ++ +D
Sbjct: 347 YTDAVVHEIQRYSDLVPT-GVPHAVTTDTKFRNYLIPK-------GTTIMALLTSVLHDD 398
Query: 213 KYFDDPSEFRPKRFA-KDSEIKKFS-FLPFGAGPRNCIGARLGEMQ 82
K F +P+ F P F K+ KK F+PF AG R C G L M+
Sbjct: 399 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 444
>DQ282153-1|ABB77901.1| 497|Homo sapiens cytochrome P450 2D6
protein.
Length = 497
Score = 64.9 bits (151), Expect = 2e-10
Identities = 46/160 (28%), Positives = 74/160 (46%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
+VA +F +AG T+S+ ++ L + H ++Q+ +Q EID+++ + D M
Sbjct: 298 VVADLF---SAGMVTTSTTLAWGLLLMILHPDVQRRVQQEIDDMIGQVRRPEMGDQA-HM 353
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P T E R F + L S I G I G +I ++ D ++ P
Sbjct: 354 PYTTAVIHEVQR-FGDIVPLGVTHMTSRDIEVQGFRIPKGTTLITNLSSVLKDEAVWEKP 412
Query: 195 SEFRPKRF--AKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F P+ F A+ +K +FLPF AG R C+G L M+
Sbjct: 413 FRFHPEHFLDAQGHFVKPEAFLPFSAGRRACLGEPLARME 452
>BC020596-1|AAH20596.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/166 (34%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = -1
Query: 552 VAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMP 373
VA +FV AG ET+S+ Y L L H E+ ++Q EID V+ RH + C MP
Sbjct: 291 VADLFV---AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP-CMQDRSHMP 346
Query: 372 LLTMAFKEALR---MFPSLGNLHRVCT----RSYTIPELGITIDPGVRIIIPAQAIQNDA 214
E R + P+ G H V T R+Y IP+ G I+ ++ +D
Sbjct: 347 YTDAVVHEIQRYSDLVPT-GVPHAVTTDTKFRNYLIPK-------GTTIMALLTSVLHDD 398
Query: 213 KYFDDPSEFRPKRFA-KDSEIKKFS-FLPFGAGPRNCIGARLGEMQ 82
K F +P+ F P F K+ KK F+PF AG R C G L M+
Sbjct: 399 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 444
>AY514490-1|AAR89907.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/166 (34%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = -1
Query: 552 VAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMP 373
VA +FV AG ET+S+ Y L L H E+ ++Q EID V+ RH + C MP
Sbjct: 291 VADLFV---AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP-CMQDRSHMP 346
Query: 372 LLTMAFKEALR---MFPSLGNLHRVCT----RSYTIPELGITIDPGVRIIIPAQAIQNDA 214
E R + P+ G H V T R+Y IP+ G I+ ++ +D
Sbjct: 347 YTDAVVHEIQRYSDLVPT-GVPHAVTTDTKFRNYLIPK-------GTTIMALLTSVLHDD 398
Query: 213 KYFDDPSEFRPKRFA-KDSEIKKFS-FLPFGAGPRNCIGARLGEMQ 82
K F +P+ F P F K+ KK F+PF AG R C G L M+
Sbjct: 399 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 444
>AL359672-5|CAH71307.1| 490|Homo sapiens cytochrome P450, family 2,
subfamily C, polypeptide 8 protein.
Length = 490
Score = 64.9 bits (151), Expect = 2e-10
Identities = 57/166 (34%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = -1
Query: 552 VAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMP 373
VA +FV AG ET+S+ Y L L H E+ ++Q EID V+ RH + C MP
Sbjct: 291 VADLFV---AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP-CMQDRSHMP 346
Query: 372 LLTMAFKEALR---MFPSLGNLHRVCT----RSYTIPELGITIDPGVRIIIPAQAIQNDA 214
E R + P+ G H V T R+Y IP+ G I+ ++ +D
Sbjct: 347 YTDAVVHEIQRYSDLVPT-GVPHAVTTDTKFRNYLIPK-------GTTIMALLTSVLHDD 398
Query: 213 KYFDDPSEFRPKRFA-KDSEIKKFS-FLPFGAGPRNCIGARLGEMQ 82
K F +P+ F P F K+ KK F+PF AG R C G L M+
Sbjct: 399 KEFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 444
>AB080265-1|BAB85489.1| 502|Homo sapiens cytochrome P450 2J2
protein.
Length = 502
Score = 64.9 bits (151), Expect = 2e-10
Identities = 49/174 (28%), Positives = 77/174 (44%), Gaps = 2/174 (1%)
Frame = -1
Query: 597 GTPVQVQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLS 418
G P E + C +F AG ET+S+ + L +A + EIQ+++Q EID V+
Sbjct: 290 GNPTSSFHEENLICSTLDLFF---AGTETTSTTLRWALLYMALYPEIQEKVQVEIDRVIG 346
Query: 417 RHDNKLCYDAILEMPLLTMAFKEALRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIII 241
+ + A MP E RM + N+ R T T+ G + G I+
Sbjct: 347 Q-GQQPSTAARESMPYTNAVIHEVQRMGNIIPLNVPREVTVDTTL--AGYHLPKGTMILT 403
Query: 240 PAQAIQNDAKYFDDPSEFRPKRFAKDSEIKK-FSFLPFGAGPRNCIGARLGEMQ 82
A+ D + P F P F ++ + KK +F+PF G R C+G +L +
Sbjct: 404 NLTALHRDPTEWATPDTFNPDHFLENGQFKKREAFMPFSIGKRACLGEQLARTE 457
>AL358613-3|CAH72804.1| 428|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 428
Score = 64.5 bits (150), Expect = 3e-10
Identities = 40/152 (26%), Positives = 73/152 (48%), Gaps = 6/152 (3%)
Frame = -1
Query: 522 GFETSSSATSYTLHQLAFHQEIQKEIQCEIDE----VLSRHDNKLCYDAILEMPLLTMAF 355
G ET++SA + + L + + ++++ E+ S DNKL + + ++ +
Sbjct: 232 GHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVI 291
Query: 354 KEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
KE LR+ P + RV +++ + G I G +I + A+ F + EF P R
Sbjct: 292 KETLRLNPPVPGGFRVALKTFELN--GYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDR 349
Query: 174 FA--KDSEIKKFSFLPFGAGPRNCIGARLGEM 85
F + +FSF+PFG G R+C+G ++
Sbjct: 350 FMLPHPEDASRFSFIPFGGGLRSCVGKEFAKI 381
>AL358613-2|CAH72803.1| 497|Homo sapiens cytochrome P450, family
26, subfamily A, polypeptide 1 protein.
Length = 497
Score = 64.5 bits (150), Expect = 3e-10
Identities = 40/152 (26%), Positives = 73/152 (48%), Gaps = 6/152 (3%)
Frame = -1
Query: 522 GFETSSSATSYTLHQLAFHQEIQKEIQCEIDE----VLSRHDNKLCYDAILEMPLLTMAF 355
G ET++SA + + L + + ++++ E+ S DNKL + + ++ +
Sbjct: 301 GHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVI 360
Query: 354 KEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
KE LR+ P + RV +++ + G I G +I + A+ F + EF P R
Sbjct: 361 KETLRLNPPVPGGFRVALKTFELN--GYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDR 418
Query: 174 FA--KDSEIKKFSFLPFGAGPRNCIGARLGEM 85
F + +FSF+PFG G R+C+G ++
Sbjct: 419 FMLPHPEDASRFSFIPFGGGLRSCVGKEFAKI 450
>AF005418-1|AAB88881.1| 497|Homo sapiens retinoic acid hydroxylase
protein.
Length = 497
Score = 64.5 bits (150), Expect = 3e-10
Identities = 40/152 (26%), Positives = 73/152 (48%), Gaps = 6/152 (3%)
Frame = -1
Query: 522 GFETSSSATSYTLHQLAFHQEIQKEIQCEIDE----VLSRHDNKLCYDAILEMPLLTMAF 355
G ET++SA + + L + + ++++ E+ S DNKL + + ++ +
Sbjct: 301 GHETTASAATSLITYLGLYPHVLQKVREELKSKGLLCKSNQDNKLDMEILEQLKYIGCVI 360
Query: 354 KEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
KE LR+ P + RV +++ + G I G +I + A+ F + EF P R
Sbjct: 361 KETLRLNPPVPGGFRVALKTFELN--GYQIPKGWNVIYSICDTHDVAEIFTNKEEFNPDR 418
Query: 174 FA--KDSEIKKFSFLPFGAGPRNCIGARLGEM 85
F + +FSF+PFG G R+C+G ++
Sbjct: 419 FMLPHPEDASRFSFIPFGGGLRSCVGKEFAKI 450
>X59812-1|CAA42481.1| 530|Homo sapiens Vitamin D3 25-hydroxylase
protein.
Length = 530
Score = 64.1 bits (149), Expect = 4e-10
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AG +T+S+ ++ L+ L+ EIQ+ + E+ V+ D MPLL KE
Sbjct: 334 AGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKD-FAHMPLLKAVLKET 392
Query: 345 LRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAK 166
LR++P + R+ + + G + + + D F +P F+P R+ +
Sbjct: 393 LRLYPVVPTNSRIIEKEIEVD--GFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLR 450
Query: 165 DSEIKK------FSFLPFGAGPRNCIGARLGEMQ 82
+S+ F +PFG G R C+G R+ E++
Sbjct: 451 NSQPATPRIQHPFGSVPFGYGVRACLGRRIAELE 484
>M62401-1|AAA52142.1| 531|Homo sapiens sterol 27-hydroxylase
protein.
Length = 531
Score = 64.1 bits (149), Expect = 4e-10
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AG +T+S+ ++ L+ L+ EIQ+ + E+ V+ D MPLL KE
Sbjct: 335 AGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKD-FAHMPLLKAVLKET 393
Query: 345 LRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAK 166
LR++P + R+ + + G + + + D F +P F+P R+ +
Sbjct: 394 LRLYPVVPTNSRIIEKEIEVD--GFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLR 451
Query: 165 DSEIKK------FSFLPFGAGPRNCIGARLGEMQ 82
+S+ F +PFG G R C+G R+ E++
Sbjct: 452 NSQPATPRIQHPFGSVPFGYGVRACLGRRIAELE 485
>M21941-1|AAA52160.1| 480|Homo sapiens CYP2C protein.
Length = 480
Score = 64.1 bits (149), Expect = 4e-10
Identities = 57/166 (34%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = -1
Query: 552 VAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMP 373
VA +FV AG ET+S+ Y L L H E+ ++Q EID V+ RH + C MP
Sbjct: 281 VADLFV---AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP-CMQDRSHMP 336
Query: 372 LLTMAFKEALR---MFPSLGNLHRVCT----RSYTIPELGITIDPGVRIIIPAQAIQNDA 214
E R + P+ G H V T R+Y IP+ G I+ ++ +D
Sbjct: 337 YTDAVVHEIQRYSDLVPT-GVPHAVTTDTKFRNYLIPK-------GTTIMALLTSVLHDD 388
Query: 213 KYFDDPSEFRPKRFA-KDSEIKKFS-FLPFGAGPRNCIGARLGEMQ 82
K F +P+ F P F K+ KK F+PF AG R C G L M+
Sbjct: 389 KEFPNPNIFDPGLFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 434
>BC051851-1|AAH51851.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 64.1 bits (149), Expect = 4e-10
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AG +T+S+ ++ L+ L+ EIQ+ + E+ V+ D MPLL KE
Sbjct: 335 AGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKD-FAHMPLLKAVLKET 393
Query: 345 LRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAK 166
LR++P + R+ + + G + + + D F +P F+P R+ +
Sbjct: 394 LRLYPVVPTNSRIIEKEIEVD--GFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLR 451
Query: 165 DSEIKK------FSFLPFGAGPRNCIGARLGEMQ 82
+S+ F +PFG G R C+G R+ E++
Sbjct: 452 NSQPATPRIQHPFGSVPFGYGVRACLGRRIAELE 485
>BC040430-1|AAH40430.1| 531|Homo sapiens cytochrome P450, family
27, subfamily A, polypeptide 1 protein.
Length = 531
Score = 64.1 bits (149), Expect = 4e-10
Identities = 40/154 (25%), Positives = 71/154 (46%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AG +T+S+ ++ L+ L+ EIQ+ + E+ V+ D MPLL KE
Sbjct: 335 AGVDTTSNTLTWALYHLSKDPEIQEALHEEVVGVVPAGQVPQHKD-FAHMPLLKAVLKET 393
Query: 345 LRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRFAK 166
LR++P + R+ + + G + + + D F +P F+P R+ +
Sbjct: 394 LRLYPVVPTNSRIIEKEIEVD--GFLFPKNTQFVFCHYVVSRDPTAFSEPESFQPHRWLR 451
Query: 165 DSEIKK------FSFLPFGAGPRNCIGARLGEMQ 82
+S+ F +PFG G R C+G R+ E++
Sbjct: 452 NSQPATPRIQHPFGSVPFGYGVRACLGRRIAELE 485
>X54741-1|CAA38539.1| 503|Homo sapiens aldosterone synthase
(P-450aldo) protein.
Length = 503
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 4/173 (2%)
Frame = -1
Query: 582 VQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCE---IDEVLSRH 412
++ E+ + I A A +T++ TL +LA + ++Q+ ++ E +S H
Sbjct: 295 LKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEH 354
Query: 411 DNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQ 232
K A E+PLL A KE LR++P L RV + + I V++ +
Sbjct: 355 PQK----ATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFL--Y 408
Query: 231 AIQNDAKYFDDPSEFRPKRFAK-DSEIKKFSFLPFGAGPRNCIGARLGEMQSL 76
++ +A F P + P+R+ + F +PFG G R C+G RL E + L
Sbjct: 409 SLGRNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEML 461
>X51535-1|CAA35915.1| 210|Homo sapiens cytochrome P-450 HPH (120
AA) protein.
Length = 210
Score = 63.7 bits (148), Expect = 5e-10
Identities = 56/166 (33%), Positives = 78/166 (46%), Gaps = 9/166 (5%)
Frame = -1
Query: 552 VAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMP 373
VA +FV AG ET+S+ Y L L H E+ ++Q EID V+ RH + C MP
Sbjct: 11 VADLFV---AGTETTSTTLRYGLLLLLKHPEVTAKVQEEIDHVIGRHRSP-CMQDRSHMP 66
Query: 372 LLTMAFKEALR---MFPSLGNLHRVCT----RSYTIPELGITIDPGVRIIIPAQAIQNDA 214
E R + P+ G H V T R+Y IP+ G I+ ++ +D
Sbjct: 67 YTDAVVHEIQRYSDLVPT-GVPHAVTTDTKFRNYLIPK-------GTTIMALLTSVLHDD 118
Query: 213 KYFDDPSEFRPKRFA-KDSEIKKFS-FLPFGAGPRNCIGARLGEMQ 82
+ F +P+ F P F K+ KK F+PF AG R C G L M+
Sbjct: 119 REFPNPNIFDPGHFLDKNGNFKKSDYFMPFSAGKRICAGEGLARME 164
>M61858-1|AAA52145.1| 370|Homo sapiens CYP2C17 protein.
Length = 370
Score = 63.7 bits (148), Expect = 5e-10
Identities = 51/174 (29%), Positives = 78/174 (44%), Gaps = 8/174 (4%)
Frame = -1
Query: 579 QPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKL 400
Q E + ++A + AG ET+S+ Y L L H E+ ++Q EI+ V+ R+ +
Sbjct: 159 QSEFTVESLIATVTDMFGAGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVVGRNRSP- 217
Query: 399 CYDAILEMPLLTMAFKEALRMFPSLGNL--HRV-CT---RSYTIPELGITIDPGVRIIIP 238
C MP E R + H V C R+Y IP+ G I+
Sbjct: 218 CMQDRSHMPYTDAVVHEVQRYIDLIPTSLPHAVTCDVKFRNYLIPK-------GTTILTS 270
Query: 237 AQAIQNDAKYFDDPSEFRPKRFAKDS-EIKKFS-FLPFGAGPRNCIGARLGEMQ 82
++ +D K F +P F P+ F + KK + F+PF AG R C+G L M+
Sbjct: 271 LTSVLHDNKEFPNPEMFDPRHFLDEGGNFKKSNYFMPFSAGKRICVGEGLARME 324
>D13752-1|BAA02899.1| 503|Homo sapiens steroid 18-hydroxylase
protein.
Length = 503
Score = 63.7 bits (148), Expect = 5e-10
Identities = 47/173 (27%), Positives = 80/173 (46%), Gaps = 4/173 (2%)
Frame = -1
Query: 582 VQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCE---IDEVLSRH 412
++ E+ + I A A +T++ TL +LA + ++Q+ ++ E +S H
Sbjct: 295 LKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRQESLAAAASISEH 354
Query: 411 DNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQ 232
K A E+PLL A KE LR++P L RV + + I V++ +
Sbjct: 355 PQK----ATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFL--Y 408
Query: 231 AIQNDAKYFDDPSEFRPKRFAK-DSEIKKFSFLPFGAGPRNCIGARLGEMQSL 76
++ +A F P + P+R+ + F +PFG G R C+G RL E + L
Sbjct: 409 SLGRNAALFPRPERYNPQRWLDIRGSGRNFHHVPFGFGMRQCLGRRLAEAEML 461
>Z00036-1|CAA77335.1| 515|Homo sapiens protein ( Human mRNA for
cytochrome P-3-450. ).
Length = 515
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>M55053-1|AAA52146.1| 515|Homo sapiens cytochrome P3-450 protein.
Length = 515
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>M31667-1|AAA52163.1| 515|Homo sapiens CYP1A2 protein.
Length = 515
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>L00389-1|AAA35738.1| 516|Homo sapiens protein ( Human cytochrome
P-450 4 gene, exon 7, and three Alu repeats in the 3'
flank. ).
Length = 516
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>DQ022432-1|AAY26399.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>BC132767-1|AAI32768.1| 544|Homo sapiens cytochrome P450, family 2,
subfamily U, polypeptide 1 protein.
Length = 544
Score = 63.3 bits (147), Expect = 7e-10
Identities = 42/160 (26%), Positives = 79/160 (49%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
I+ +F+ AG +T++++ + L ++ + ++Q+++ EI+ V+ + D +M
Sbjct: 345 IIGDLFI---AGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKA-QM 400
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P E R+ + T T+ + G TI G I+ ++ D ++ P
Sbjct: 401 PYTEATIMEVQRLTVVVPLAIPHMTSENTVLQ-GYTIPKGTLILPNLWSVHRDPAIWEKP 459
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEMQ 82
+F P RF D IKK +F+PFG G R C+G +L +M+
Sbjct: 460 EDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKME 499
>BC067428-1|AAH67428.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>BC067427-1|AAH67427.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>BC067426-1|AAH67426.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>BC067425-1|AAH67425.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>BC067424-1|AAH67424.1| 516|Homo sapiens cytochrome P450, family 1,
subfamily A, polypeptide 2 protein.
Length = 516
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>AY343323-1|AAQ21380.1| 544|Homo sapiens cytochrome P450 protein.
Length = 544
Score = 63.3 bits (147), Expect = 7e-10
Identities = 42/160 (26%), Positives = 79/160 (49%), Gaps = 2/160 (1%)
Frame = -1
Query: 555 IVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEM 376
I+ +F+ AG +T++++ + L ++ + ++Q+++ EI+ V+ + D +M
Sbjct: 345 IIGDLFI---AGTDTTTNSLLWCLLYMSLNPDVQEKVHEEIERVIGANRAPSLTDKA-QM 400
Query: 375 PLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDP 196
P E R+ + T T+ + G TI G I+ ++ D ++ P
Sbjct: 401 PYTEATIMEVQRLTVVVPLAIPHMTSENTVLQ-GYTIPKGTLILPNLWSVHRDPAIWEKP 459
Query: 195 SEFRPKRFAKDSE--IKKFSFLPFGAGPRNCIGARLGEMQ 82
+F P RF D IKK +F+PFG G R C+G +L +M+
Sbjct: 460 EDFYPNRFLDDQGQLIKKETFIPFGIGKRVCMGEQLAKME 499
>AF253322-2|AAK25728.1| 516|Homo sapiens cytochrome P450 protein.
Length = 516
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>AF182274-1|AAF13599.1| 516|Homo sapiens cytochrome P450-1A2
protein.
Length = 516
Score = 63.3 bits (147), Expect = 7e-10
Identities = 49/154 (31%), Positives = 74/154 (48%), Gaps = 6/154 (3%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AGF+T ++A S++L L EIQ++IQ E+D V+ R D ++P L E
Sbjct: 317 AGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDR-PQLPYLEAFILET 375
Query: 345 LRMFPSLG-NLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKRF- 172
R L + TR T+ G I + + + +D + ++DPSEFRP+RF
Sbjct: 376 FRHSSFLPFTIPHSTTRDTTLN--GFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFL 433
Query: 171 -AKDSEIKK---FSFLPFGAGPRNCIGARLGEMQ 82
A + I K + FG G R CIG L + +
Sbjct: 434 TADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWE 467
>M21939-1|AAA52158.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 61.7 bits (143), Expect = 2e-09
Identities = 50/156 (32%), Positives = 71/156 (45%), Gaps = 8/156 (5%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AG ET+S+ Y L L H E+ ++Q EI+ V+ R+ + C MP E
Sbjct: 292 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSP-CMQDRSHMPYTDAVVHEV 350
Query: 345 LRMFPSLGNL--HRV-CT---RSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFR 184
R L H V C R+Y IP+ G I+I ++ +D K F +P F
Sbjct: 351 QRCIDLLPTSLPHAVTCDIKFRNYLIPK-------GTTILISLTSVLHDNKEFPNPEMFD 403
Query: 183 PKRFAKDSEIKKFS--FLPFGAGPRNCIGARLGEMQ 82
P F + + K S F+PF AG R C+G L M+
Sbjct: 404 PHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGME 439
>M15331-1|AAA52157.1| 485|Homo sapiens CYP2C protein.
Length = 485
Score = 61.7 bits (143), Expect = 2e-09
Identities = 50/156 (32%), Positives = 71/156 (45%), Gaps = 8/156 (5%)
Frame = -1
Query: 525 AGFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVLSRHDNKLCYDAILEMPLLTMAFKEA 346
AG ET+S+ Y L L H E+ ++Q EI+ V+ R+ + C MP E
Sbjct: 292 AGTETTSTTLRYALLLLLKHPEVTAKVQEEIERVIGRNRSP-CMQDRSHMPYTDAVVHEV 350
Query: 345 LRMFPSLGNL--HRV-CT---RSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFR 184
R L H V C R+Y IP+ G I+I ++ +D K F +P F
Sbjct: 351 QRCIDLLPTSLPHAVTCDIKFRNYLIPK-------GTTILISLTSVLHDNKEFPNPEMFD 403
Query: 183 PKRFAKDSEIKKFS--FLPFGAGPRNCIGARLGEMQ 82
P F + + K S F+PF AG R C+G L M+
Sbjct: 404 PHHFLDEGDNFKKSKYFMPFSAGKRICVGEALAGME 439
>M32881-1|AAA35741.1| 503|Homo sapiens protein ( Human steroid
11-beta-hydroxylase-like-enzyme (CYP11B2) gene, exon 9.
).
Length = 503
Score = 61.3 bits (142), Expect = 3e-09
Identities = 46/173 (26%), Positives = 79/173 (45%), Gaps = 4/173 (2%)
Frame = -1
Query: 582 VQPEMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCE---IDEVLSRH 412
++ E+ + I A A +T++ TL +LA + ++Q+ ++ E +S H
Sbjct: 295 LKAELSLEAIKANSMELTAGSVDTTAFPLLMTLFELARNPDVQQILRKESLAAAASISEH 354
Query: 411 DNKLCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQ 232
K A E+PLL A KE LR++P L RV + + I V++ +
Sbjct: 355 PQK----ATTELPLLRAALKETLRLYPVGLFLERVVSSDLVLQNYHIPAGTLVQVFL--Y 408
Query: 231 AIQNDAKYFDDPSEFRPKRFAK-DSEIKKFSFLPFGAGPRNCIGARLGEMQSL 76
++ +A F P + P+R+ + +PFG G R C+G RL E + L
Sbjct: 409 SLGRNAALFPRPERYNPQRWLDIRGSGRNLHHVPFGFGMRQCLGRRLAEAEML 461
>AF478474-1|AAL84813.1| 503|Homo sapiens mutated cytochrome
P-450c11 protein protein.
Length = 503
Score = 61.3 bits (142), Expect = 3e-09
Identities = 47/170 (27%), Positives = 74/170 (43%), Gaps = 4/170 (2%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCE---IDEVLSRHDNK 403
E+ I A A +T+ TL +LA + +Q+ ++ E +S H K
Sbjct: 298 ELSPDAIKANSMELTAGSMDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQK 357
Query: 402 LCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQ 223
A E+PLL A KE LR++P L RV + + I VR+ + ++
Sbjct: 358 ----ATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFL--YSLG 411
Query: 222 NDAKYFDDPSEFRPKRFAK-DSEIKKFSFLPFGAGPRNCIGARLGEMQSL 76
+ F P + P+R+ + F +PFG G R C+G RL E + L
Sbjct: 412 RNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEML 461
>X58906-1|CAA41709.1| 495|Homo sapiens steroid 21-monooxygenase
protein.
Length = 495
Score = 60.9 bits (141), Expect = 4e-09
Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 4/151 (2%)
Frame = -1
Query: 522 GFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVL--SRHDNKLCYDAILEMPLLTMAFKE 349
G ET+++ S+ + L H EIQ+ +Q E+D L +++ Y +PLL E
Sbjct: 293 GTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDHARLPLLNATIAE 352
Query: 348 ALRMFP--SLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
LR+ P L HR TR +I G I G II Q D ++ P EF P R
Sbjct: 353 VLRLRPVVPLALPHRT-TRPSSIS--GYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDR 409
Query: 174 FAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F + K L FG G R C+G L ++
Sbjct: 410 FLEPG--KNSRALAFGCGARVCLGEPLARLE 438
>M32879-1|AAA52149.1| 503|Homo sapiens CYP11B1 protein.
Length = 503
Score = 60.9 bits (141), Expect = 4e-09
Identities = 47/170 (27%), Positives = 74/170 (43%), Gaps = 4/170 (2%)
Frame = -1
Query: 573 EMDTKCIVAQMFVFXAAGFETSSSATSYTLHQLAFHQEIQKEIQCE---IDEVLSRHDNK 403
E+ I A A +T+ TL +LA + +Q+ ++ E +S H K
Sbjct: 298 ELSPDAIKANSMELTAGSVDTTVFPLLMTLFELARNPNVQQALRQESLAAAASISEHPQK 357
Query: 402 LCYDAILEMPLLTMAFKEALRMFPSLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQ 223
A E+PLL A KE LR++P L RV + + I VR+ + ++
Sbjct: 358 ----ATTELPLLRAALKETLRLYPVGLFLERVASSDLVLQNYHIPAGTLVRVFL--YSLG 411
Query: 222 NDAKYFDDPSEFRPKRFAK-DSEIKKFSFLPFGAGPRNCIGARLGEMQSL 76
+ F P + P+R+ + F +PFG G R C+G RL E + L
Sbjct: 412 RNPALFPRPERYNPQRWLDIRGSGRNFYHVPFGFGMRQCLGRRLAEAEML 461
>M28548-1|AAA52065.1| 495|Homo sapiens protein ( Human mutant
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 60.9 bits (141), Expect = 4e-09
Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 4/151 (2%)
Frame = -1
Query: 522 GFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVL--SRHDNKLCYDAILEMPLLTMAFKE 349
G ET+++ S+ + L H EIQ+ +Q E+D L +++ Y +PLL E
Sbjct: 293 GTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAE 352
Query: 348 ALRMFP--SLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
LR+ P L HR TR +I G I G II Q D ++ P EF P R
Sbjct: 353 VLRLRPVVPLALPHRT-TRPSSIS--GYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDR 409
Query: 174 FAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F + K L FG G R C+G L ++
Sbjct: 410 FLEPG--KNSRALAFGCGARVCLGEPLARLE 438
>M26856-1|AAA52064.1| 495|Homo sapiens protein ( Human
21-hydroxylase B gene, complete cds. ).
Length = 495
Score = 60.9 bits (141), Expect = 4e-09
Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 4/151 (2%)
Frame = -1
Query: 522 GFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVL--SRHDNKLCYDAILEMPLLTMAFKE 349
G ET+++ S+ + L H EIQ+ +Q E+D L +++ Y +PLL E
Sbjct: 293 GTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAE 352
Query: 348 ALRMFP--SLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
LR+ P L HR TR +I G I G II Q D ++ P EF P R
Sbjct: 353 VLRLRPVVPLALPHRT-TRPSSIS--GYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDR 409
Query: 174 FAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F + K L FG G R C+G L ++
Sbjct: 410 FLEPG--KNSRALAFGCGARVCLGEPLARLE 438
>M21550-1|AAA52063.1| 495|Homo sapiens CYP21 protein.
Length = 495
Score = 60.9 bits (141), Expect = 4e-09
Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 4/151 (2%)
Frame = -1
Query: 522 GFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVL--SRHDNKLCYDAILEMPLLTMAFKE 349
G ET+++ S+ + L H EIQ+ +Q E+D L +++ Y +PLL E
Sbjct: 293 GTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAE 352
Query: 348 ALRMFP--SLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
LR+ P L HR TR +I G I G II Q D ++ P EF P R
Sbjct: 353 VLRLRPVVPLALPHRT-TRPSSIS--GYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDR 409
Query: 174 FAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F + K L FG G R C+G L ++
Sbjct: 410 FLEPG--KNSRALAFGCGARVCLGEPLARLE 438
>M13936-1|AAA59695.1| 494|Homo sapiens CYP21P protein.
Length = 494
Score = 60.9 bits (141), Expect = 4e-09
Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 4/151 (2%)
Frame = -1
Query: 522 GFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVL--SRHDNKLCYDAILEMPLLTMAFKE 349
G ET+++ S+ + L H EIQ+ +Q E+D L +++ Y +PLL E
Sbjct: 292 GTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAE 351
Query: 348 ALRMFP--SLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
LR+ P L HR TR +I G I G II Q D ++ P EF P R
Sbjct: 352 VLRLRPVVPLALPHRT-TRPSSIS--GYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDR 408
Query: 174 FAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F + K L FG G R C+G L ++
Sbjct: 409 FLEPG--KNSRALAFGCGARVCLGEPLARLE 437
>BX679671-8|CAM26070.1| 494|Homo sapiens cytochrome P450, family
21, subfamily A, polypeptide 2 protein.
Length = 494
Score = 60.9 bits (141), Expect = 4e-09
Identities = 49/151 (32%), Positives = 69/151 (45%), Gaps = 4/151 (2%)
Frame = -1
Query: 522 GFETSSSATSYTLHQLAFHQEIQKEIQCEIDEVL--SRHDNKLCYDAILEMPLLTMAFKE 349
G ET+++ S+ + L H EIQ+ +Q E+D L +++ Y +PLL E
Sbjct: 292 GTETTANTLSWAVVFLLHHPEIQQRLQEELDHELGPGASSSRVPYKDRARLPLLNATIAE 351
Query: 348 ALRMFP--SLGNLHRVCTRSYTIPELGITIDPGVRIIIPAQAIQNDAKYFDDPSEFRPKR 175
LR+ P L HR TR +I G I G II Q D ++ P EF P R
Sbjct: 352 VLRLRPVVPLALPHRT-TRPSSIS--GYDIPEGTVIIPNLQGAHLDETVWERPHEFWPDR 408
Query: 174 FAKDSEIKKFSFLPFGAGPRNCIGARLGEMQ 82
F + K L FG G R C+G L ++
Sbjct: 409 FLEPG--KNSRALAFGCGARVCLGEPLARLE 437
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 92,976,237
Number of Sequences: 237096
Number of extensions: 1941809
Number of successful extensions: 4675
Number of sequences better than 10.0: 427
Number of HSP's better than 10.0 without gapping: 4085
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4275
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7253890590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -