Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV13m07r
(785 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 176 9e-44
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 176 9e-44
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 176 9e-44
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 176 9e-44
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 174 3e-43
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 173 5e-43
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 164 3e-40
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 164 4e-40
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 164 4e-40
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 153 5e-37
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 140 5e-33
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 85 4e-16
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 85 4e-16
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 85 4e-16
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 80 8e-15
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 80 8e-15
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 80 8e-15
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 80 8e-15
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 80 8e-15
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 78 3e-14
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 78 3e-14
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 78 3e-14
BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein. 73 9e-13
U83246-1|AAC15920.1| 537|Homo sapiens copine I protein. 35 0.38
CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein. 35 0.38
BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein. 35 0.38
AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein. 35 0.38
AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein. 35 0.38
AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein. 35 0.38
AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein. 35 0.38
BC066597-1|AAH66597.1| 537|Homo sapiens copine III protein. 33 1.5
BC036242-1|AAH36242.1| 537|Homo sapiens copine III protein. 33 1.5
AF077226-1|AAD46074.2| 537|Homo sapiens copine III protein. 33 1.5
AB014536-1|BAA31611.2| 540|Homo sapiens KIAA0636 protein protein. 33 1.5
BC053658-1|AAH53658.1| 548|Homo sapiens CPNE2 protein protein. 30 8.2
AF542551-1|AAQ09534.1| 446|Homo sapiens unknown protein. 30 8.2
AF492484-1|AAO85483.1| 548|Homo sapiens copine III-like related... 30 8.2
AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation ... 30 8.2
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 176 bits (428), Expect = 9e-44
Identities = 85/219 (38%), Positives = 131/219 (59%), Gaps = 1/219 (0%)
Frame = -3
Query: 699 LYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTG 520
L+A+PIF + G +P+ + +A S K+GYP SR+PEFT+EE+++++G +DFF V +YT
Sbjct: 253 LFAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTT 311
Query: 519 FLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDP 340
L+ E + + + IL D + + P W W+ + P + L Y++ YN+P
Sbjct: 312 RLIKYQE--NKKGELGILQDAEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNP 367
Query: 339 IFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLE 163
+ YITENG+ L D R Y+R + + + + L+ Y AWSL+DNFEW +
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 162 GYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 176 bits (428), Expect = 9e-44
Identities = 85/219 (38%), Positives = 131/219 (59%), Gaps = 1/219 (0%)
Frame = -3
Query: 699 LYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTG 520
L+A+PIF + G +P+ + +A S K+GYP SR+PEFT+EE+++++G +DFF V +YT
Sbjct: 253 LFAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTT 311
Query: 519 FLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDP 340
L+ E + + + IL D + + P W W+ + P + L Y++ YN+P
Sbjct: 312 RLIKYQE--NKKGELGILQDAEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNP 367
Query: 339 IFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLE 163
+ YITENG+ L D R Y+R + + + + L+ Y AWSL+DNFEW +
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 162 GYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 176 bits (428), Expect = 9e-44
Identities = 85/219 (38%), Positives = 131/219 (59%), Gaps = 1/219 (0%)
Frame = -3
Query: 699 LYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTG 520
L+A+PIF + G +P+ + +A S K+GYP SR+PEFT+EE+++++G +DFF V +YT
Sbjct: 253 LFAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTT 311
Query: 519 FLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDP 340
L+ E + + + IL D + + P W W+ + P + L Y++ YN+P
Sbjct: 312 RLIKYQE--NKKGELGILQDAEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNP 367
Query: 339 IFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLE 163
+ YITENG+ L D R Y+R + + + + L+ Y AWSL+DNFEW +
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 162 GYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 176 bits (428), Expect = 9e-44
Identities = 85/219 (38%), Positives = 131/219 (59%), Gaps = 1/219 (0%)
Frame = -3
Query: 699 LYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTG 520
L+A+PIF + G +P+ + +A S K+GYP SR+PEFT+EE+++++G +DFF V +YT
Sbjct: 253 LFAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTT 311
Query: 519 FLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDP 340
L+ E + + + IL D + + P W W+ + P + L Y++ YN+P
Sbjct: 312 RLIKYQE--NKKGELGILQDAEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNP 367
Query: 339 IFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLE 163
+ YITENG+ L D R Y+R + + + + L+ Y AWSL+DNFEW +
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 162 GYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 174 bits (423), Expect = 3e-43
Identities = 84/219 (38%), Positives = 130/219 (59%), Gaps = 1/219 (0%)
Frame = -3
Query: 699 LYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTG 520
L+A+PIF + G +P+ + +A S K+GYP SR+PEFT+EE+++++G +DFF V +YT
Sbjct: 253 LFAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTT 311
Query: 519 FLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDP 340
L+ E + + + L D + + P W W+ + P + L Y++ YN+P
Sbjct: 312 RLIKYQE--NKKGELGTLQDAEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNP 367
Query: 339 IFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLE 163
+ YITENG+ L D R Y+R + + + + L+ Y AWSL+DNFEW +
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 162 GYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 173 bits (422), Expect = 5e-43
Identities = 85/219 (38%), Positives = 130/219 (59%), Gaps = 1/219 (0%)
Frame = -3
Query: 699 LYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTG 520
L+A+PIF + G +P+ + +A S K+GYP SR+PEFT+EE+++++G +DFF V + T
Sbjct: 253 LFAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYCTT 311
Query: 519 FLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDP 340
L+ E + R + IL D + + P W W+ + P + L Y++ YN+P
Sbjct: 312 RLIKYQE--NKRGELGILQDAEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNP 367
Query: 339 IFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLE 163
+ YITENG+ L D R Y+R + + + + L+ Y AWSL+DNFEW +
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 162 GYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 164 bits (399), Expect = 3e-40
Identities = 84/222 (37%), Positives = 120/222 (54%), Gaps = 2/222 (0%)
Frame = -3
Query: 720 RRQAEF--GLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGASD 547
RR +F G +A PIF + G + + + + ++S G SR+PEFT+ E+ + G D
Sbjct: 1618 RRYVQFMGGWFAHPIF-KNGDYSEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYD 1676
Query: 546 FFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLT 367
FFG NHYT L + + D V + WP S S+WL ++P L
Sbjct: 1677 FFGFNHYTTVLAYNLNYATAISSFDA--DRGVASIADRSWPDSGSFWLKMTPFGFRRILN 1734
Query: 366 YLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAGIRLKGYMAWSL 187
+L++ YNDP Y+TENG S L D RI Y R + L + + L+GY WS
Sbjct: 1735 WLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDLRGYTVWSA 1794
Query: 186 MDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
MDNFEW G++ERFGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1795 MDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 140 bits (339), Expect = 5e-33
Identities = 85/228 (37%), Positives = 117/228 (51%), Gaps = 2/228 (0%)
Frame = -3
Query: 741 DHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELV 562
D A + Q G +A PIF G +P + V +S + SR+P FT+EE+ +
Sbjct: 1139 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 1197
Query: 561 RGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSI 382
R +D F +N Y +V + P+ D + P WP +A +P
Sbjct: 1198 RATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWPSTAMN--RAAPWGT 1253
Query: 381 YDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDC--LDAGIRLK 208
L ++++ Y D YITENG N D DRI Y++ + L LD GI L+
Sbjct: 1254 RRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINEALKAYRLD-GIDLR 1311
Query: 207 GYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 1312 GYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 135 bits (327), Expect = 1e-31
Identities = 75/232 (32%), Positives = 131/232 (56%), Gaps = 5/232 (2%)
Frame = -3
Query: 744 EDHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEEREL 565
ED A+E G +A P+F + G +P L + + + + +P +++PEFT+ E++L
Sbjct: 615 EDLRASERFLHFMLGWFAHPVFVD-GDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQL 673
Query: 564 VRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDS 385
++G++DF G++HYT L+S Q + P+ + + ++ WPQ++S W+ + P
Sbjct: 674 LKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNHVWPQTSSSWIRVVPWG 731
Query: 384 IYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRYYRAALESVLDCL-DAG 220
I L ++ Y PI Y+ NG + L DD R+ Y+ + VL + +
Sbjct: 732 IRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDS 790
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
+ ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 791 VDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSII 842
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 164 bits (398), Expect = 4e-40
Identities = 84/222 (37%), Positives = 120/222 (54%), Gaps = 2/222 (0%)
Frame = -3
Query: 720 RRQAEF--GLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGASD 547
RR +F G +A PIF + G + + + + ++S G SR+PEFT+ E+ + G D
Sbjct: 1618 RRYVQFMGGWFAHPIF-KNGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYD 1676
Query: 546 FFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLT 367
FFG NHYT L + + D V + WP S S+WL ++P L
Sbjct: 1677 FFGFNHYTTVLAYNLNYATAISSFDA--DRGVASIADRSWPDSGSFWLKMTPFGFRRILN 1734
Query: 366 YLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAGIRLKGYMAWSL 187
+L++ YNDP Y+TENG S L D RI Y R + L + + L+GY WS
Sbjct: 1735 WLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDLRGYTVWSA 1794
Query: 186 MDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
MDNFEW G++ERFGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1795 MDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 140 bits (339), Expect = 5e-33
Identities = 85/228 (37%), Positives = 117/228 (51%), Gaps = 2/228 (0%)
Frame = -3
Query: 741 DHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELV 562
D A + Q G +A PIF G +P + V +S + SR+P FT+EE+ +
Sbjct: 1139 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 1197
Query: 561 RGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSI 382
R +D F +N Y +V + P+ D + P WP +A +P
Sbjct: 1198 RATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWPSTAMN--RAAPWGT 1253
Query: 381 YDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDC--LDAGIRLK 208
L ++++ Y D YITENG N D DRI Y++ + L LD GI L+
Sbjct: 1254 RRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINEALKAYRLD-GIDLR 1311
Query: 207 GYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 1312 GYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 135 bits (327), Expect = 1e-31
Identities = 75/232 (32%), Positives = 131/232 (56%), Gaps = 5/232 (2%)
Frame = -3
Query: 744 EDHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEEREL 565
ED A+E G +A P+F + G +P L + + + + +P +++PEFT+ E++L
Sbjct: 615 EDLRASERFLHFMLGWFAHPVFVD-GDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQL 673
Query: 564 VRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDS 385
++G++DF G++HYT L+S Q + P+ + + ++ WPQ++S W+ + P
Sbjct: 674 LKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNHVWPQTSSSWIRVVPWG 731
Query: 384 IYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRYYRAALESVLDCL-DAG 220
I L ++ Y PI Y+ NG + L DD R+ Y+ + VL + +
Sbjct: 732 IRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDS 790
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
+ ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 791 VDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSII 842
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 164 bits (398), Expect = 4e-40
Identities = 84/222 (37%), Positives = 120/222 (54%), Gaps = 2/222 (0%)
Frame = -3
Query: 720 RRQAEF--GLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGASD 547
RR +F G +A PIF + G + + + + ++S G SR+PEFT+ E+ + G D
Sbjct: 1618 RRYVQFMGGWFAHPIF-KNGDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYD 1676
Query: 546 FFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLT 367
FFG NHYT L + + D V + WP S S+WL ++P L
Sbjct: 1677 FFGFNHYTTVLAYNLNYATAISSFDA--DRGVASIADRSWPDSGSFWLKMTPFGFRRILN 1734
Query: 366 YLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAGIRLKGYMAWSL 187
+L++ YNDP Y+TENG S L D RI Y R + L + + L+GY WS
Sbjct: 1735 WLKEEYNDPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDLRGYTVWSA 1794
Query: 186 MDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
MDNFEW G++ERFGL+ V++SDP+ PR P+ SA Y ++R
Sbjct: 1795 MDNFEWATGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 140 bits (339), Expect = 5e-33
Identities = 85/228 (37%), Positives = 117/228 (51%), Gaps = 2/228 (0%)
Frame = -3
Query: 741 DHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELV 562
D A + Q G +A PIF G +P + V +S + SR+P FT+EE+ +
Sbjct: 1139 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 1197
Query: 561 RGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSI 382
R +D F +N Y +V + P+ D + P WP +A +P
Sbjct: 1198 RATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWPSTAMN--RAAPWGT 1253
Query: 381 YDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDC--LDAGIRLK 208
L ++++ Y D YITENG N D DRI Y++ + L LD GI L+
Sbjct: 1254 RRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINEALKAYRLD-GIDLR 1311
Query: 207 GYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 1312 GYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 1359
Score = 135 bits (327), Expect = 1e-31
Identities = 75/232 (32%), Positives = 131/232 (56%), Gaps = 5/232 (2%)
Frame = -3
Query: 744 EDHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEEREL 565
ED A+E G +A P+F + G +P L + + + + +P +++PEFT+ E++L
Sbjct: 615 EDLRASERFLHFMLGWFAHPVFVD-GDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQL 673
Query: 564 VRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDS 385
++G++DF G++HYT L+S Q + P+ + + ++ WPQ++S W+ + P
Sbjct: 674 LKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNHVWPQTSSSWIRVVPWG 731
Query: 384 IYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRYYRAALESVLDCL-DAG 220
I L ++ Y PI Y+ NG + L DD R+ Y+ + VL + +
Sbjct: 732 IRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDS 790
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
+ ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 791 VDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSII 842
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 153 bits (372), Expect = 5e-37
Identities = 78/229 (34%), Positives = 124/229 (54%), Gaps = 2/229 (0%)
Frame = -3
Query: 744 EDHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEEREL 565
+D A E Q G +A PI++ G +P+ + + + KSA++G SR+P F+ +E+
Sbjct: 274 KDLEAAERYLQFCLGWFANPIYA--GDYPQVMKDYIGRKSAEQGLEMSRLPVFSLQEKSY 331
Query: 564 VRGASDFFGVNHYTG-FLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPD 388
++G SDF G+ H+T ++ N P+ D+ + P WP S WL P
Sbjct: 332 IKGTSDFLGLGHFTTRYITERNYPSRQGPSYQNDRDLI--ELVDPNWPDLGSKWLYSVPW 389
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSP-PTNGLLDDDRIRYYRAALESVLDCLDAGIRL 211
L + Q +Y DP Y+ ENG S L D+ RI+Y + + +L + G +
Sbjct: 390 GFRRLLNFAQTQYGDPPIYVMENGASQKFHCTQLCDEWRIQYLKGYINEMLKAIKDGANI 449
Query: 210 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
KGY +WSL+D FEW +GY++R+G Y V+F+D +PR P+ S YK+I+
Sbjct: 450 KGYTSWSLLDKFEWEKGYSDRYGFYYVEFNDRNKPRYPKASVQYYKKII 498
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 140 bits (339), Expect = 5e-33
Identities = 85/228 (37%), Positives = 117/228 (51%), Gaps = 2/228 (0%)
Frame = -3
Query: 741 DHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELV 562
D A + Q G +A PIF G +P + V +S + SR+P FT+EE+ +
Sbjct: 571 DVEAADRMLQFSLGWFAHPIF-RNGDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFI 629
Query: 561 RGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSI 382
R +D F +N Y +V + P+ D + P WP +A +P
Sbjct: 630 RATADVFCLNTYYSRIVQHKTPRLNPPSYE--DDQEMAEEEDPSWPSTAMN--RAAPWGT 685
Query: 381 YDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDC--LDAGIRLK 208
L ++++ Y D YITENG N D DRI Y++ + L LD GI L+
Sbjct: 686 RRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDTDRIFYHKTYINEALKAYRLD-GIDLR 743
Query: 207 GYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
GY+AWSLMDNFEWL GYT +FGLY VDF++ RPRT R SA Y E++
Sbjct: 744 GYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVI 791
Score = 135 bits (327), Expect = 1e-31
Identities = 75/232 (32%), Positives = 131/232 (56%), Gaps = 5/232 (2%)
Frame = -3
Query: 744 EDHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEEREL 565
ED A+E G +A P+F + G +P L + + + + +P +++PEFT+ E++L
Sbjct: 47 EDLRASERFLHFMLGWFAHPVFVD-GDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQL 105
Query: 564 VRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDS 385
++G++DF G++HYT L+S Q + P+ + + ++ WPQ++S W+ + P
Sbjct: 106 LKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNHVWPQTSSSWIRVVPWG 163
Query: 384 IYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRYYRAALESVLDCL-DAG 220
I L ++ Y PI Y+ NG + L DD R+ Y+ + VL + +
Sbjct: 164 IRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDS 222
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
+ ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKSA+ + I+
Sbjct: 223 VDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSII 274
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 84.6 bits (200), Expect = 4e-16
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = -3
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 211
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 210 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 73.3 bits (172), Expect = 9e-13
Identities = 69/212 (32%), Positives = 101/212 (47%), Gaps = 9/212 (4%)
Frame = -3
Query: 732 ATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGA 553
A E Q E +AEP+F + G +P + E +A K + G S +P T+ ER L++G
Sbjct: 760 AAERFLQFEIAWFAEPLF-KTGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGT 817
Query: 552 SDFFGVNHYTGFLVSANEQI------SDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 391
DF +NH+T V +EQ+ SDR I L DIT S+ L + P
Sbjct: 818 VDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQDIT---------RLSSPTRLAVIP 866
Query: 390 DSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAA--LESVLDC-LDAG 220
+ L ++++ Y D YIT +G + L+DDR+R Y L+ VL L
Sbjct: 867 WGVRKLLRWVRRNYGDMDIYITASGID----DQALEDDRLRKYYLGKYLQEVLKAYLIDK 922
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 124
+R+KGY A+ L + E RFG + DF
Sbjct: 923 VRIKGYYAFKLAE-----EKSKPRFGFFTSDF 949
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 84.6 bits (200), Expect = 4e-16
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = -3
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 211
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 210 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 73.3 bits (172), Expect = 9e-13
Identities = 69/212 (32%), Positives = 101/212 (47%), Gaps = 9/212 (4%)
Frame = -3
Query: 732 ATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGA 553
A E Q E +AEP+F + G +P + E +A K + G S +P T+ ER L++G
Sbjct: 760 AAERFLQFEIAWFAEPLF-KTGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGT 817
Query: 552 SDFFGVNHYTGFLVSANEQI------SDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 391
DF +NH+T V +EQ+ SDR I L DIT S+ L + P
Sbjct: 818 VDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQDIT---------RLSSPTRLAVIP 866
Query: 390 DSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAA--LESVLDC-LDAG 220
+ L ++++ Y D YIT +G + L+DDR+R Y L+ VL L
Sbjct: 867 WGVRKLLRWVRRNYGDMDIYITASGID----DQALEDDRLRKYYLGKYLQEVLKAYLIDK 922
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 124
+R+KGY A+ L + E RFG + DF
Sbjct: 923 VRIKGYYAFKLAE-----EKSKPRFGFFTSDF 949
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 84.6 bits (200), Expect = 4e-16
Identities = 42/110 (38%), Positives = 61/110 (55%), Gaps = 1/110 (0%)
Frame = -3
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 211
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 210 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 61
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 73.3 bits (172), Expect = 9e-13
Identities = 69/212 (32%), Positives = 101/212 (47%), Gaps = 9/212 (4%)
Frame = -3
Query: 732 ATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGA 553
A E Q E +AEP+F + G +P + E +A K + G S +P T+ ER L++G
Sbjct: 760 AAERFLQFEIAWFAEPLF-KTGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGT 817
Query: 552 SDFFGVNHYTGFLVSANEQI------SDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 391
DF +NH+T V +EQ+ SDR I L DIT S+ L + P
Sbjct: 818 VDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQDIT---------RLSSPTRLAVIP 866
Query: 390 DSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAA--LESVLDC-LDAG 220
+ L ++++ Y D YIT +G + L+DDR+R Y L+ VL L
Sbjct: 867 WGVRKLLRWVRRNYGDMDIYITASGID----DQALEDDRLRKYYLGKYLQEVLKAYLIDK 922
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 124
+R+KGY A+ L + E RFG + DF
Sbjct: 923 VRIKGYYAFKLAE-----EKSKPRFGFFTSDF 949
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 80.2 bits (189), Expect = 8e-15
Identities = 65/230 (28%), Positives = 109/230 (47%), Gaps = 4/230 (1%)
Frame = -3
Query: 741 DHAATELRRQAEF--GLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERE 568
DH+ E ++ +F G +A+P+F + G +P+ + ++ S +P+FT+ E++
Sbjct: 37 DHSIKECQKSLDFVLGWFAKPVFID-GDYPESMKNNLS----------SILPDFTESEKK 85
Query: 567 LVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPD 388
++G +DFF + F + + Q+ D P + P Q S W+ L
Sbjct: 86 FIKGTADFFAL----CFGPTLSFQLLD-------PHMKFRQLESPNLRQLLS-WIDL--- 130
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLDAGIR 214
+N P +I ENGW T DD + YY + +E++ G+
Sbjct: 131 -----------EFNHPQIFIVENGWFVSGTT-KRDDAKYMYYLKKFIMETLKAIKLDGVD 178
Query: 213 LKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
+ GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 179 VIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 228
Score = 61.3 bits (142), Expect = 4e-09
Identities = 67/243 (27%), Positives = 114/243 (46%), Gaps = 8/243 (3%)
Frame = -3
Query: 762 PFTDXEEDHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFT 583
PF+ +++ A L + + G AEPIF G +P + + + +++ +P FT
Sbjct: 467 PFSQKDKEVAERVL--EFDIGWLAEPIFGS-GDYPWVMRDWLNQRNN------FLLPYFT 517
Query: 582 DEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPEWPQSA 415
++E++L++G DF ++HYT LV + ++ +D + + DIT W S
Sbjct: 518 EDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT--------WLNSP 569
Query: 414 SYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY---RAALE 247
S + + P + L +L+ +Y D YI NG +GL +DD++R Y E
Sbjct: 570 SQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQNYINE 624
Query: 246 SVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEI 67
++ + GI L GY A+S D RFGLY +D P+ K Y++I
Sbjct: 625 ALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKI 674
Query: 66 LRS 58
+ S
Sbjct: 675 IDS 677
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 80.2 bits (189), Expect = 8e-15
Identities = 65/230 (28%), Positives = 109/230 (47%), Gaps = 4/230 (1%)
Frame = -3
Query: 741 DHAATELRRQAEF--GLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERE 568
DH+ E ++ +F G +A+P+F + G +P+ + ++ S +P+FT+ E++
Sbjct: 310 DHSIKECQKSLDFVLGWFAKPVFID-GDYPESMKNNLS----------SILPDFTESEKK 358
Query: 567 LVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPD 388
++G +DFF + F + + Q+ D P + P Q S W+ L
Sbjct: 359 FIKGTADFFAL----CFGPTLSFQLLD-------PHMKFRQLESPNLRQLLS-WIDL--- 403
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLDAGIR 214
+N P +I ENGW T DD + YY + +E++ G+
Sbjct: 404 -----------EFNHPQIFIVENGWFVSGTT-KRDDAKYMYYLKKFIMETLKAIKLDGVD 451
Query: 213 LKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
+ GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 452 VIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 61.3 bits (142), Expect = 4e-09
Identities = 67/243 (27%), Positives = 114/243 (46%), Gaps = 8/243 (3%)
Frame = -3
Query: 762 PFTDXEEDHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFT 583
PF+ +++ A L + + G AEPIF G +P + + + +++ +P FT
Sbjct: 740 PFSQKDKEVAERVL--EFDIGWLAEPIFGS-GDYPWVMRDWLNQRNN------FLLPYFT 790
Query: 582 DEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPEWPQSA 415
++E++L++G DF ++HYT LV + ++ +D + + DIT W S
Sbjct: 791 EDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT--------WLNSP 842
Query: 414 SYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY---RAALE 247
S + + P + L +L+ +Y D YI NG +GL +DD++R Y E
Sbjct: 843 SQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQNYINE 897
Query: 246 SVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEI 67
++ + GI L GY A+S D RFGLY +D P+ K Y++I
Sbjct: 898 ALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKI 947
Query: 66 LRS 58
+ S
Sbjct: 948 IDS 950
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 80.2 bits (189), Expect = 8e-15
Identities = 65/230 (28%), Positives = 109/230 (47%), Gaps = 4/230 (1%)
Frame = -3
Query: 741 DHAATELRRQAEF--GLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERE 568
DH+ E ++ +F G +A+P+F + G +P+ + ++ S +P+FT+ E++
Sbjct: 310 DHSIKECQKSLDFVLGWFAKPVFID-GDYPESMKNNLS----------SILPDFTESEKK 358
Query: 567 LVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPD 388
++G +DFF + F + + Q+ D P + P Q S W+ L
Sbjct: 359 FIKGTADFFAL----CFGPTLSFQLLD-------PHMKFRQLESPNLRQLLS-WIDL--- 403
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLDAGIR 214
+N P +I ENGW T DD + YY + +E++ G+
Sbjct: 404 -----------EFNHPQIFIVENGWFVSGTT-KRDDAKYMYYLKKFIMETLKAIKLDGVD 451
Query: 213 LKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
+ GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 452 VIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 80.2 bits (189), Expect = 8e-15
Identities = 65/230 (28%), Positives = 109/230 (47%), Gaps = 4/230 (1%)
Frame = -3
Query: 741 DHAATELRRQAEF--GLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERE 568
DH+ E ++ +F G +A+P+F + G +P+ + ++ S +P+FT+ E++
Sbjct: 310 DHSIKECQKSLDFVLGWFAKPVFID-GDYPESMKNNLS----------SILPDFTESEKK 358
Query: 567 LVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPD 388
++G +DFF + F + + Q+ D P + P Q S W+ L
Sbjct: 359 FIKGTADFFAL----CFGPTLSFQLLD-------PHMKFRQLESPNLRQLLS-WIDL--- 403
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLDAGIR 214
+N P +I ENGW T DD + YY + +E++ G+
Sbjct: 404 -----------EFNHPQIFIVENGWFVSGTT-KRDDAKYMYYLKKFIMETLKAIKLDGVD 451
Query: 213 LKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
+ GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 452 VIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 61.3 bits (142), Expect = 4e-09
Identities = 67/243 (27%), Positives = 114/243 (46%), Gaps = 8/243 (3%)
Frame = -3
Query: 762 PFTDXEEDHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFT 583
PF+ +++ A L + + G AEPIF G +P + + + +++ +P FT
Sbjct: 740 PFSQKDKEVAERVL--EFDIGWLAEPIFGS-GDYPWVMRDWLNQRNN------FLLPYFT 790
Query: 582 DEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPEWPQSA 415
++E++L++G DF ++HYT LV + ++ +D + + DIT W S
Sbjct: 791 EDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT--------WLNSP 842
Query: 414 SYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY---RAALE 247
S + + P + L +L+ +Y D YI NG +GL +DD++R Y E
Sbjct: 843 SQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQNYINE 897
Query: 246 SVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEI 67
++ + GI L GY A+S D RFGLY +D P+ K Y++I
Sbjct: 898 ALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKI 947
Query: 66 LRS 58
+ S
Sbjct: 948 IDS 950
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 80.2 bits (189), Expect = 8e-15
Identities = 65/230 (28%), Positives = 109/230 (47%), Gaps = 4/230 (1%)
Frame = -3
Query: 741 DHAATELRRQAEF--GLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERE 568
DH+ E ++ +F G +A+P+F + G +P+ + ++ S +P+FT+ E++
Sbjct: 310 DHSIKECQKSLDFVLGWFAKPVFID-GDYPESMKNNLS----------SILPDFTESEKK 358
Query: 567 LVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPD 388
++G +DFF + F + + Q+ D P + P Q S W+ L
Sbjct: 359 FIKGTADFFAL----CFGPTLSFQLLD-------PHMKFRQLESPNLRQLLS-WIDL--- 403
Query: 387 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLDAGIR 214
+N P +I ENGW T DD + YY + +E++ G+
Sbjct: 404 -----------EFNHPQIFIVENGWFVSGTT-KRDDAKYMYYLKKFIMETLKAIKLDGVD 451
Query: 213 LKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 64
+ GY AWSLMD FEW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 452 VIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 61.3 bits (142), Expect = 4e-09
Identities = 67/243 (27%), Positives = 114/243 (46%), Gaps = 8/243 (3%)
Frame = -3
Query: 762 PFTDXEEDHAATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFT 583
PF+ +++ A L + + G AEPIF G +P + + + +++ +P FT
Sbjct: 740 PFSQKDKEVAERVL--EFDIGWLAEPIFGS-GDYPWVMRDWLNQRNN------FLLPYFT 790
Query: 582 DEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPEWPQSA 415
++E++L++G DF ++HYT LV + ++ +D + + DIT W S
Sbjct: 791 EDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT--------WLNSP 842
Query: 414 SYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY---RAALE 247
S + + P + L +L+ +Y D YI NG +GL +DD++R Y E
Sbjct: 843 SQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQNYINE 897
Query: 246 SVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEI 67
++ + GI L GY A+S D RFGLY +D P+ K Y++I
Sbjct: 898 ALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKI 947
Query: 66 LRS 58
+ S
Sbjct: 948 IDS 950
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 78.2 bits (184), Expect = 3e-14
Identities = 32/58 (55%), Positives = 43/58 (74%)
Frame = -3
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 78.2 bits (184), Expect = 3e-14
Identities = 32/58 (55%), Positives = 43/58 (74%)
Frame = -3
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 78.2 bits (184), Expect = 3e-14
Identities = 32/58 (55%), Positives = 43/58 (74%)
Frame = -3
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 46
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein.
Length = 305
Score = 73.3 bits (172), Expect = 9e-13
Identities = 69/212 (32%), Positives = 101/212 (47%), Gaps = 9/212 (4%)
Frame = -3
Query: 732 ATELRRQAEFGLYAEPIFSEEGGFPKELVEIVAEKSAKEGYPWSRIPEFTDEERELVRGA 553
A E Q E +AEP+F + G +P + E +A K + G S +P T+ ER L++G
Sbjct: 21 AAERFLQFEIAWFAEPLF-KTGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGT 78
Query: 552 SDFFGVNHYTGFLVSANEQI------SDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 391
DF +NH+T V +EQ+ SDR I L DIT S+ L + P
Sbjct: 79 VDFCALNHFTTRFVM-HEQLAGSRYDSDRD-IQFLQDIT---------RLSSPTRLAVIP 127
Query: 390 DSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAA--LESVLDC-LDAG 220
+ L ++++ Y D YIT +G + L+DDR+R Y L+ VL L
Sbjct: 128 WGVRKLLRWVRRNYGDMDIYITASGID----DQALEDDRLRKYYLGKYLQEVLKAYLIDK 183
Query: 219 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDF 124
+R+KGY A+ L + E RFG + DF
Sbjct: 184 VRIKGYYAFKLAE-----EKSKPRFGFFTSDF 210
>U83246-1|AAC15920.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.38
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.38
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.38
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein.
Length = 386
Score = 34.7 bits (76), Expect = 0.38
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 288 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 341
>AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein.
Length = 481
Score = 34.7 bits (76), Expect = 0.38
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.38
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein.
Length = 517
Score = 34.7 bits (76), Expect = 0.38
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 292 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 345
>BC066597-1|AAH66597.1| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>BC036242-1|AAH36242.1| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>AF077226-1|AAD46074.2| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>AB014536-1|BAA31611.2| 540|Homo sapiens KIAA0636 protein protein.
Length = 540
Score = 32.7 bits (71), Expect = 1.5
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 379
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 321 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 374
>BC053658-1|AAH53658.1| 548|Homo sapiens CPNE2 protein protein.
Length = 548
Score = 30.3 bits (65), Expect = 8.2
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 391
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 334 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 383
>AF542551-1|AAQ09534.1| 446|Homo sapiens unknown protein.
Length = 446
Score = 30.3 bits (65), Expect = 8.2
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 391
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 232 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 281
>AF492484-1|AAO85483.1| 548|Homo sapiens copine III-like related
protein protein.
Length = 548
Score = 30.3 bits (65), Expect = 8.2
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -3
Query: 540 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 391
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 334 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 383
>AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation
factor 1 variant protein.
Length = 208
Score = 30.3 bits (65), Expect = 8.2
Identities = 14/25 (56%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = -2
Query: 112 PPSHPAQV-RLRLQGDLEKQGHRPR 41
PP HPA + R R G L +GHRPR
Sbjct: 71 PPPHPASISRPRPPGPLPLRGHRPR 95
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 113,692,290
Number of Sequences: 237096
Number of extensions: 2586811
Number of successful extensions: 5507
Number of sequences better than 10.0: 38
Number of HSP's better than 10.0 without gapping: 5219
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5458
length of database: 76,859,062
effective HSP length: 89
effective length of database: 55,757,518
effective search space used: 9590293096
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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