Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV13m07f
(663 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 219 5e-57
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 219 5e-57
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 219 5e-57
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 219 5e-57
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 198 1e-50
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 187 4e-47
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 187 4e-47
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 187 4e-47
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 187 4e-47
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 187 4e-47
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 186 6e-47
Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein. 184 2e-46
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 184 2e-46
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 184 2e-46
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 184 2e-46
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 184 2e-46
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 160 5e-39
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 160 5e-39
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 160 5e-39
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 99 7e-21
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 99 7e-21
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 99 1e-20
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 87 4e-17
BC025719-1|AAH25719.1| 390|Homo sapiens matrix metallopeptidase... 32 1.6
AL691432-6|CAM12835.1| 390|Homo sapiens matrix metallopeptidase... 32 1.6
AJ005256-1|CAB38176.1| 390|Homo sapiens MMP-23 protein. 32 1.6
AF057062-1|AAC62618.1| 249|Homo sapiens metalloprotease mmp21/2... 32 1.6
AF057061-1|AAC62617.1| 265|Homo sapiens metalloprotease mmp21/2... 32 1.6
AF056200-1|AAC62616.1| 390|Homo sapiens metalloprotease mmp21/2... 32 1.6
AF055334-3|AAC63529.1| 250|Homo sapiens metalloprotease isoform... 32 1.6
AF055334-2|AAC63528.1| 266|Homo sapiens metalloprotease isoform... 32 1.6
AF055334-1|AAC63527.1| 390|Homo sapiens metalloprotease isoform... 32 1.6
AB031068-1|BAA92769.1| 390|Homo sapiens MIFR/Femalysin protein. 32 1.6
AB010961-1|BAA24833.1| 390|Homo sapiens MIFR-1 protein. 32 1.6
BT007435-1|AAP36103.1| 441|Homo sapiens G protein-coupled recep... 32 2.1
BC125081-1|AAI25082.1| 486|Homo sapiens G protein-coupled recep... 32 2.1
BC125080-1|AAI25081.1| 486|Homo sapiens G protein-coupled recep... 32 2.1
BC110848-1|AAI10849.1| 486|Homo sapiens G protein-coupled recep... 32 2.1
BC016860-1|AAH16860.2| 448|Homo sapiens GPRC5C protein protein. 32 2.1
AK075397-1|BAC11595.1| 441|Homo sapiens protein ( Homo sapiens ... 32 2.1
AJ276102-1|CAC00633.1| 441|Homo sapiens GPRC5C protein. 32 2.1
AF207989-1|AAF72870.1| 441|Homo sapiens orphan G-protein couple... 32 2.1
BC034469-1|AAH34469.1| 849|Homo sapiens coiled-coil domain cont... 30 6.4
AK001648-1|BAA91808.1| 849|Homo sapiens protein ( Homo sapiens ... 30 6.4
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 219 bits (536), Expect = 5e-57
Identities = 96/174 (55%), Positives = 124/174 (71%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGS 605
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGS 1076
Score = 204 bits (498), Expect = 2e-52
Identities = 92/192 (47%), Positives = 128/192 (66%), Gaps = 1/192 (0%)
Frame = +3
Query: 81 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -ILNATAIGTYL 653
+ N Y+
Sbjct: 1555 GVSNRPGTAPYI 1566
Score = 173 bits (420), Expect = 6e-43
Identities = 83/196 (42%), Positives = 118/196 (60%), Gaps = 1/196 (0%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 251
Q FP+ FL G +T ++ +EG W E G+G +IWD P +G +T ++A++SYH
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435
Query: 252 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 431
V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495
Query: 432 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVH 611
FHWDLPQ LQ+ GG+ N F DYA ++ FGDRVK W+T +EP + Y GYG+
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQ 555
Query: 612 KAPILNATAIGTYLCA 659
P ++ + ++ A
Sbjct: 556 HPPGISDPGVASFKVA 571
Score = 58.8 bits (136), Expect = 2e-08
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +3
Query: 297 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 473
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
FA+ F DYA + +FGD V W T ++ E+ E
Sbjct: 147 FAD-----LFADYATFAFHSFGDLVGIWFTFSDLEEVIKE 181
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 219 bits (536), Expect = 5e-57
Identities = 96/174 (55%), Positives = 124/174 (71%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGS 605
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGS 1076
Score = 204 bits (498), Expect = 2e-52
Identities = 92/192 (47%), Positives = 128/192 (66%), Gaps = 1/192 (0%)
Frame = +3
Query: 81 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -ILNATAIGTYL 653
+ N Y+
Sbjct: 1555 GVSNRPGTAPYI 1566
Score = 173 bits (420), Expect = 6e-43
Identities = 83/196 (42%), Positives = 118/196 (60%), Gaps = 1/196 (0%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 251
Q FP+ FL G +T ++ +EG W E G+G +IWD P +G +T ++A++SYH
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435
Query: 252 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 431
V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495
Query: 432 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVH 611
FHWDLPQ LQ+ GG+ N F DYA ++ FGDRVK W+T +EP + Y GYG+
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQ 555
Query: 612 KAPILNATAIGTYLCA 659
P ++ + ++ A
Sbjct: 556 HPPGISDPGVASFKVA 571
Score = 58.8 bits (136), Expect = 2e-08
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +3
Query: 297 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 473
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
FA+ F DYA + +FGD V W T ++ E+ E
Sbjct: 147 FAD-----LFADYATFAFHSFGDLVGIWFTFSDLEEVIKE 181
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 219 bits (536), Expect = 5e-57
Identities = 96/174 (55%), Positives = 124/174 (71%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 335 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 394
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 395 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 454
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGS 605
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS
Sbjct: 455 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGS 508
Score = 205 bits (500), Expect = 1e-52
Identities = 90/181 (49%), Positives = 125/181 (69%)
Frame = +3
Query: 81 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 808 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 866
Query: 261 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 867 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 926
Query: 441 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 927 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 986
Query: 621 I 623
+
Sbjct: 987 V 987
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 219 bits (536), Expect = 5e-57
Identities = 96/174 (55%), Positives = 124/174 (71%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
F DDFL G ++++YQIEGAW+ DGKG +IWD TH + VKD +TGDIA +SYH ++ D
Sbjct: 903 FRDDFLWGVSSSAYQIEGAWDADGKGPSIWDNFTHTPGSNVKDNATGDIACDSYHQLDAD 962
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ M+R L + YRFS+SWSRI P+G + IN GVDYYNRLIN ++ I PM+TLFHWD
Sbjct: 963 LNMLRALKVKAYRFSISWSRIFPTGRNSSINSHGVDYYNRLINGLVASNIFPMVTLFHWD 1022
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGS 605
LPQ LQ++GG+ NP F+ YA + FGDRVK W+T NEP + + GYGS
Sbjct: 1023 LPQALQDIGGWENPALIDLFDSYADFCFQTFGDRVKFWMTFNEPMYLAWLGYGS 1076
Score = 204 bits (498), Expect = 2e-52
Identities = 92/192 (47%), Positives = 128/192 (66%), Gaps = 1/192 (0%)
Frame = +3
Query: 81 RFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVER 260
RFP+ F+ A+A+YQIEGAW DGKG +IWD +H P V++ + GD+A +SYH +
Sbjct: 1376 RFPEGFIWSAASAAYQIEGAWRADGKGLSIWDTFSHT-PLRVENDAIGDVACDSYHKIAE 1434
Query: 261 DVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
D+ ++ LG+ YRFS+SWSRILP G INEAG++YY RLI+ +L I P +T++HW
Sbjct: 1435 DLVTLQNLGVSHYRFSISWSRILPDGTTRYINEAGLNYYVRLIDTLLAASIQPQVTIYHW 1494
Query: 441 DLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
DLPQ LQ++GG+ N F++YA V++ GD+VK WIT+NEP I Y+GYG AP
Sbjct: 1495 DLPQTLQDVGGWENETIVQRFKEYADVLFQRLGDKVKFWITLNEPFVIAYQGYGYGTAAP 1554
Query: 621 -ILNATAIGTYL 653
+ N Y+
Sbjct: 1555 GVSNRPGTAPYI 1566
Score = 173 bits (420), Expect = 6e-43
Identities = 83/196 (42%), Positives = 118/196 (60%), Gaps = 1/196 (0%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG-STGDIAANSYHN 251
Q FP+ FL G +T ++ +EG W E G+G +IWD P +G +T ++A++SYH
Sbjct: 379 QDTFPEGFLWGASTGAFNVEGGWAEGGRGVSIWD---PRRPLNTTEGQATLEVASDSYHK 435
Query: 252 VERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITL 431
V DV ++ L VY+FS+SWSRI P G + + GV YYN+LI+ + GI PM TL
Sbjct: 436 VASDVALLCGLRAQVYKFSISWSRIFPMGHGSSPSLPGVAYYNKLIDRLQDAGIEPMATL 495
Query: 432 FHWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVH 611
FHWDLPQ LQ+ GG+ N F DYA ++ FGDRVK W+T +EP + Y GYG+
Sbjct: 496 FHWDLPQALQDHGGWQNESVVDAFLDYAAFCFSTFGDRVKLWVTFHEPWVMSYAGYGTGQ 555
Query: 612 KAPILNATAIGTYLCA 659
P ++ + ++ A
Sbjct: 556 HPPGISDPGVASFKVA 571
Score = 58.8 bits (136), Expect = 2e-08
Identities = 33/100 (33%), Positives = 50/100 (50%), Gaps = 1/100 (1%)
Frame = +3
Query: 297 YRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWDLP-QKLQELGG 473
Y+ LSW+++LP+G +E V Y RL+ + + PM+ L H LP L+
Sbjct: 87 YKVFLSWAQLLPAGSTQNPDEKTVQCYRRLLKALKTARLQPMVILHHQTLPASTLRRTEA 146
Query: 474 FANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYE 593
FA+ F DYA + +FGD V W T ++ E+ E
Sbjct: 147 FAD-----LFADYATFAFHSFGDLVGIWFTFSDLEEVIKE 181
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 198 bits (483), Expect = 1e-50
Identities = 88/194 (45%), Positives = 128/194 (65%), Gaps = 2/194 (1%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F G +++YQ EGAW++DGKG +IWD TH+ V T D+A + Y+ V+ D
Sbjct: 37 FPLGFSWGVGSSAYQTEGAWDQDGKGPSIWDVFTHSGKGKVLGNETADVACDGYYKVQED 96
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGF-ANEINEAGVDYYNRLINEMLKYGITPMITLFHW 440
+ ++REL ++ YRFSLSW R+LP+G A ++N+ G+++Y+ LI+ +L ITP++TL HW
Sbjct: 97 IILLRELHVNHYRFSLSWPRLLPTGIRAEQVNKKGIEFYSDLIDALLSSNITPIVTLHHW 156
Query: 441 DLPQKLQ-ELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKA 617
DLPQ LQ + GG+ N + +F DYA + + FGDRVKHWIT ++PR + +GY + H A
Sbjct: 157 DLPQLLQVKYGGWQNVSMANYFRDYANLCFEAFGDRVKHWITFSDPRAMAEKGYETGHHA 216
Query: 618 PILNATAIGTYLCA 659
P L G Y A
Sbjct: 217 PGLKLRGTGLYKAA 230
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 187 bits (455), Expect = 4e-47
Identities = 82/172 (47%), Positives = 114/172 (66%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 599
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 187 bits (455), Expect = 4e-47
Identities = 82/172 (47%), Positives = 114/172 (66%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 599
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 187 bits (455), Expect = 4e-47
Identities = 82/172 (47%), Positives = 114/172 (66%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 599
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 187 bits (455), Expect = 4e-47
Identities = 82/172 (47%), Positives = 114/172 (66%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 599
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 187 bits (455), Expect = 4e-47
Identities = 82/172 (47%), Positives = 114/172 (66%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 599
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 123 LPQTLEDQGGWLSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 186 bits (453), Expect = 6e-47
Identities = 82/172 (47%), Positives = 114/172 (66%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
++ +++LGL YRFSLSWSR+LP G IN+ G+DYYN++I+++LK G+TP++TL+H+D
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKGIDYYNKIIDDLLKNGVTPIVTLYHFD 122
Query: 444 LPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGY 599
LPQ L++ GG+ + F+ YA+ ++ FGDRVK WITINE + Y
Sbjct: 123 LPQTLEDQGGWWSEAIIESFDKYAQFCFSTFGDRVKQWITINEANVLSVMSY 174
>Z92540-2|CAC94767.1| 273|Homo sapiens 179I15.1 (klotho) protein.
Length = 273
Score = 184 bits (449), Expect = 2e-46
Identities = 90/211 (42%), Positives = 129/211 (61%), Gaps = 16/211 (7%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 566
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPREICYEGYGSVHKAPILNATAIGTYLCA 659
+ P + + GY + AP + + YL A
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVA 268
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 184 bits (449), Expect = 2e-46
Identities = 90/211 (42%), Positives = 129/211 (61%), Gaps = 16/211 (7%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 566
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPREICYEGYGSVHKAPILNATAIGTYLCA 659
+ P + + GY + AP + + YL A
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVA 268
Score = 87.4 bits (207), Expect = 4e-17
Identities = 54/193 (27%), Positives = 96/193 (49%), Gaps = 12/193 (6%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEP--REIC 587
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP R +
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMT 696
Query: 588 YEGYGSVHKAPIL 626
Y ++ KA L
Sbjct: 697 YSAGHNLLKAHAL 709
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 184 bits (449), Expect = 2e-46
Identities = 90/211 (42%), Positives = 129/211 (61%), Gaps = 16/211 (7%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 566
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPREICYEGYGSVHKAPILNATAIGTYLCA 659
+ P + + GY + AP + + YL A
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVA 268
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 184 bits (449), Expect = 2e-46
Identities = 90/211 (42%), Positives = 129/211 (61%), Gaps = 16/211 (7%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 566
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPREICYEGYGSVHKAPILNATAIGTYLCA 659
+ P + + GY + AP + + YL A
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVA 268
Score = 87.4 bits (207), Expect = 4e-17
Identities = 54/193 (27%), Positives = 96/193 (49%), Gaps = 12/193 (6%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEP--REIC 587
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP R +
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMT 696
Query: 588 YEGYGSVHKAPIL 626
Y ++ KA L
Sbjct: 697 YSAGHNLLKAHAL 709
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 184 bits (449), Expect = 2e-46
Identities = 90/211 (42%), Positives = 129/211 (61%), Gaps = 16/211 (7%)
Frame = +3
Query: 75 QRRFPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDG------------- 215
Q FPD FL +A+YQ EG W + GKG +IWD TH+ A D
Sbjct: 58 QGTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHHPLAPPGDSRNASLPLGAPSPL 117
Query: 216 --STGDIAANSYHNVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLI 389
+TGD+A++SY+NV RD E +RELG+ YRFS+SW+R+LP+G A N G+ YY RL+
Sbjct: 118 QPATGDVASDSYNNVFRDTEALRELGVTHYRFSISWARVLPNGSAGVPNREGLRYYRRLL 177
Query: 390 NEMLKYGITPMITLFHWDLPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITI 566
+ + G+ P++TL+HWDLPQ+LQ+ GG+AN + F DYA + + +FG +VK+WITI
Sbjct: 178 ERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITI 237
Query: 567 NEPREICYEGYGSVHKAPILNATAIGTYLCA 659
+ P + + GY + AP + + YL A
Sbjct: 238 DNPYVVAWHGYATGRLAPGIRGSPRLGYLVA 268
Score = 87.4 bits (207), Expect = 4e-17
Identities = 54/193 (27%), Positives = 96/193 (49%), Gaps = 12/193 (6%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 519 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 576
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 577 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 636
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEP--REIC 587
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP R +
Sbjct: 637 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMT 696
Query: 588 YEGYGSVHKAPIL 626
Y ++ KA L
Sbjct: 697 YSAGHNLLKAHAL 709
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 160 bits (388), Expect = 5e-39
Identities = 72/180 (40%), Positives = 112/180 (62%), Gaps = 1/180 (0%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP +F G T + Q+EG+W +DGKG +IWD+ H + +K+ S+ + +++SY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
LP LQE GG+ N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Score = 94.7 bits (225), Expect = 3e-19
Identities = 49/146 (33%), Positives = 80/146 (54%), Gaps = 12/146 (8%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREIC-- 587
L+ H LP+ L G+ NP + F+ YA + + GD VK WITINEP +
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDI 700
Query: 588 -----YEGYGSVHKAPILNATAIGTY 650
+ YG+ H + +A A Y
Sbjct: 701 YNRSGNDTYGAAHNLLVAHALAWRLY 726
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 160 bits (388), Expect = 5e-39
Identities = 72/180 (40%), Positives = 112/180 (62%), Gaps = 1/180 (0%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP +F G T + Q+EG+W +DGKG +IWD+ H + +K+ S+ + +++SY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
LP LQE GG+ N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Score = 94.7 bits (225), Expect = 3e-19
Identities = 49/146 (33%), Positives = 80/146 (54%), Gaps = 12/146 (8%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREIC-- 587
L+ H LP+ L G+ NP + F+ YA + + GD VK WITINEP +
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDI 700
Query: 588 -----YEGYGSVHKAPILNATAIGTY 650
+ YG+ H + +A A Y
Sbjct: 701 YNRSGNDTYGAAHNLLVAHALAWRLY 726
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 160 bits (388), Expect = 5e-39
Identities = 72/180 (40%), Positives = 112/180 (62%), Gaps = 1/180 (0%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP +F G T + Q+EG+W +DGKG +IWD+ H + +K+ S+ + +++SY +E+D
Sbjct: 81 FPKNFFWGIGTGALQVEGSWKKDGKGPSIWDHFIHTH---LKNVSSTNGSSDSYIFLEKD 137
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMITLFHWD 443
+ + +G+ Y+FS+SW R+ P G N G+ YY+ L++ ++ I P++TL+HWD
Sbjct: 138 LSALDFIGVSFYQFSISWPRLFPDGIVTVANAKGLQYYSTLLDALVLRNIEPIVTLYHWD 197
Query: 444 LPQKLQE-LGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREICYEGYGSVHKAP 620
LP LQE GG+ N F DYA + FGDRVK+WITI+ P + + GYG+ AP
Sbjct: 198 LPLALQEKYGGWKNDTIIDIFNDYATYCFQMFGDRVKYWITIHNPYLVAWHGYGTGMHAP 257
Score = 94.7 bits (225), Expect = 3e-19
Identities = 49/146 (33%), Positives = 80/146 (54%), Gaps = 12/146 (8%)
Frame = +3
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
N+++ +EM+ + + YRF+L W+ +LP+G + +N + YY +++E LK GI+ M+T
Sbjct: 581 NIKKQLEMLARMKVTHYRFALDWASVLPTGNLSAVNRQALRYYRCVVSEGLKLGISAMVT 640
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEPREIC-- 587
L+ H LP+ L G+ NP + F+ YA + + GD VK WITINEP +
Sbjct: 641 LYYPTHAHLGLPEPLLHADGWLNPSTAEAFQAYAGLCFQELGDLVKLWITINEPNRLSDI 700
Query: 588 -----YEGYGSVHKAPILNATAIGTY 650
+ YG+ H + +A A Y
Sbjct: 701 YNRSGNDTYGAAHNLLVAHALAWRLY 726
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99 bits (238), Expect = 7e-21
Identities = 45/95 (47%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 368
++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99 bits (238), Expect = 7e-21
Identities = 45/95 (47%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGPCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 368
++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 99.1 bits (236), Expect = 1e-20
Identities = 45/95 (47%), Positives = 58/95 (61%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSYHNVERD 263
FP F ATA+YQ+EG W+ DGKG +WD TH V TGD+A SY E D
Sbjct: 3 FPAGFGWAAATAAYQVEGGWDADGKGLCVWDTFTHQGGERVFKNQTGDVACGSYTLWEED 62
Query: 264 VEMMRELGLDVYRFSLSWSRILPSGFANEINEAGV 368
++ +++LGL YRFSLSWSR+LP G IN+ +
Sbjct: 63 LKCIKQLGLTHYRFSLSWSRLLPDGTTGFINQKAI 97
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 87.4 bits (207), Expect = 4e-17
Identities = 54/193 (27%), Positives = 96/193 (49%), Gaps = 12/193 (6%)
Frame = +3
Query: 84 FPDDFLIGTATASYQIEGAWNE-DGKGENIWDYLTHNNPAAVKDGSTGDIAANSY----H 248
FP DF G Q++ ++ +WD H++ +K SY
Sbjct: 246 FPCDFAWGVVDNYIQVDTTLSQFTDLNVYLWD--VHHSKRLIKVDGVVTKKRKSYCVDFA 303
Query: 249 NVERDVEMMRELGLDVYRFSLSWSRILPSGFANEINEAGVDYYNRLINEMLKYGITPMIT 428
++ + +++E+ + +RFSL W+ ILP G +++N + YY + +E+++ ITP++
Sbjct: 304 AIQPQIALLQEMHVTHFRFSLDWALILPLGNQSQVNHTILQYYRCMASELVRVNITPVVA 363
Query: 429 LF-----HWDLPQKLQELGGFANPLASIWFEDYARVVYTNFGDRVKHWITINEP--REIC 587
L+ + LP+ L G + NP ++ F +YAR+ + G VK WIT+NEP R +
Sbjct: 364 LWQPMAPNQGLPRLLARQGAWENPYTALAFAEYARLCFQELGHHVKLWITMNEPYTRNMT 423
Query: 588 YEGYGSVHKAPIL 626
Y ++ KA L
Sbjct: 424 YSAGHNLLKAHAL 436
>BC025719-1|AAH25719.1| 390|Homo sapiens matrix metallopeptidase
23B protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AL691432-6|CAM12835.1| 390|Homo sapiens matrix metallopeptidase
23B protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AJ005256-1|CAB38176.1| 390|Homo sapiens MMP-23 protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AF057062-1|AAC62618.1| 249|Homo sapiens metalloprotease mmp21/22C
protein.
Length = 249
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 210 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 247
>AF057061-1|AAC62617.1| 265|Homo sapiens metalloprotease mmp21/22B
protein.
Length = 265
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 226 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 263
>AF056200-1|AAC62616.1| 390|Homo sapiens metalloprotease mmp21/22A
protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AF055334-3|AAC63529.1| 250|Homo sapiens metalloprotease isoform C
protein.
Length = 250
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 210 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 247
>AF055334-2|AAC63528.1| 266|Homo sapiens metalloprotease isoform B
protein.
Length = 266
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 226 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 263
>AF055334-1|AAC63527.1| 390|Homo sapiens metalloprotease isoform A
protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AB031068-1|BAA92769.1| 390|Homo sapiens MIFR/Femalysin protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>AB010961-1|BAA24833.1| 390|Homo sapiens MIFR-1 protein.
Length = 390
Score = 32.3 bits (70), Expect = 1.6
Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 3/38 (7%)
Frame = +3
Query: 552 HWITINEPREICYEGY---GSVHKAPILNATAIGTYLC 656
+W EP E Y GY G H + I NA GTY C
Sbjct: 333 YWYKDQEPLEFSYPGYLALGEAHLSIIANAVNEGTYTC 370
>BT007435-1|AAP36103.1| 441|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 441
Score = 31.9 bits (69), Expect = 2.1
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>BC125081-1|AAI25082.1| 486|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 486
Score = 31.9 bits (69), Expect = 2.1
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483
>BC125080-1|AAI25081.1| 486|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 486
Score = 31.9 bits (69), Expect = 2.1
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483
>BC110848-1|AAI10849.1| 486|Homo sapiens G protein-coupled
receptor, family C, group 5, member C protein.
Length = 486
Score = 31.9 bits (69), Expect = 2.1
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 433 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 483
>BC016860-1|AAH16860.2| 448|Homo sapiens GPRC5C protein protein.
Length = 448
Score = 31.9 bits (69), Expect = 2.1
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 395 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 445
>AK075397-1|BAC11595.1| 441|Homo sapiens protein ( Homo sapiens
cDNA PSEC0087 fis, clone PLACE1001022, highly similar to
G protein-coupled receptor, family C, group 5, member C
isoform ).
Length = 441
Score = 31.9 bits (69), Expect = 2.1
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>AJ276102-1|CAC00633.1| 441|Homo sapiens GPRC5C protein.
Length = 441
Score = 31.9 bits (69), Expect = 2.1
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>AF207989-1|AAF72870.1| 441|Homo sapiens orphan G-protein coupled
receptor protein.
Length = 441
Score = 31.9 bits (69), Expect = 2.1
Identities = 14/51 (27%), Positives = 25/51 (49%)
Frame = +3
Query: 93 DFLIGTATASYQIEGAWNEDGKGENIWDYLTHNNPAAVKDGSTGDIAANSY 245
D ++ ATA+ Q+ G+ N + E+++ +H KDG + N Y
Sbjct: 388 DIILPRATANSQVMGSANSTLRAEDMYSAQSHQAATPPKDGKNSQVFRNPY 438
>BC034469-1|AAH34469.1| 849|Homo sapiens coiled-coil domain
containing 87 protein.
Length = 849
Score = 30.3 bits (65), Expect = 6.4
Identities = 12/21 (57%), Positives = 15/21 (71%)
Frame = +1
Query: 67 PSSREGFRMTSSSGLPPPPTR 129
PS REG+R+ GLPP P+R
Sbjct: 313 PSLREGWRLADELGLPPLPSR 333
>AK001648-1|BAA91808.1| 849|Homo sapiens protein ( Homo sapiens
cDNA FLJ10786 fis, clone NT2RP4000480. ).
Length = 849
Score = 30.3 bits (65), Expect = 6.4
Identities = 12/21 (57%), Positives = 15/21 (71%)
Frame = +1
Query: 67 PSSREGFRMTSSSGLPPPPTR 129
PS REG+R+ GLPP P+R
Sbjct: 313 PSLREGWRLADELGLPPLPSR 333
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 96,715,448
Number of Sequences: 237096
Number of extensions: 1952319
Number of successful extensions: 4825
Number of sequences better than 10.0: 44
Number of HSP's better than 10.0 without gapping: 4566
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4795
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7478817430
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
- SilkBase 1999-2023 -