Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV13d21r
(756 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC063302-1|AAH63302.1| 1278|Homo sapiens Niemann-Pick disease, t... 100 1e-20
AF338230-1|AAK25791.1| 1278|Homo sapiens Niemann-Pick disease C1... 100 1e-20
AF157379-1|AAD48006.1| 1278|Homo sapiens Niemann-Pick C1 protein... 100 1e-20
AF002020-1|AAB63982.1| 1278|Homo sapiens Niemann-Pick C disease ... 100 1e-20
AB209048-1|BAD92285.1| 1289|Homo sapiens Niemann-Pick disease, t... 100 1e-20
BC117178-1|AAI17179.1| 1332|Homo sapiens NPC1L1 protein protein. 87 5e-17
AY515256-1|AAS56939.1| 1332|Homo sapiens NPC1L1 splice variant p... 87 5e-17
AY437865-1|AAR97886.1| 1332|Homo sapiens Niemann-Pick C1-like 1 ... 87 5e-17
AF192522-1|AAF20396.1| 1359|Homo sapiens Niemann-Pick C1-like pr... 87 5e-17
AF123046-1|AAF28875.1| 190|Homo sapiens Niemann-Pick C1 disease... 69 1e-11
U59464-1|AAC50550.1| 1447|Homo sapiens PATCHED protein. 63 9e-10
AL161729-2|CAH73818.1| 1296|Homo sapiens patched homolog 1 (Dros... 63 9e-10
AL161729-1|CAH73817.1| 1447|Homo sapiens patched homolog 1 (Dros... 63 9e-10
AY438664-1|AAR05447.1| 1203|Homo sapiens patched homolog 2 (Dros... 63 1e-09
AY359016-1|AAQ89375.1| 1203|Homo sapiens Patched 2 protein. 63 1e-09
AY358555-1|AAQ88919.1| 1211|Homo sapiens Patched 2 protein. 63 1e-09
AL592166-5|CAI13000.1| 1203|Homo sapiens patched homolog 2 (Dros... 63 1e-09
AL136380-1|CAI23127.1| 1203|Homo sapiens patched homolog 2 (Dros... 63 1e-09
AF119569-1|AAD17260.1| 1146|Homo sapiens patched 2 protein. 63 1e-09
AF091501-1|AAC79847.1| 1203|Homo sapiens receptor protein patche... 63 1e-09
AF087651-1|AAD25953.1| 1203|Homo sapiens patched 2 protein. 63 1e-09
U43148-1|AAC50496.1| 1296|Homo sapiens PTC protein. 61 5e-09
AY395772-1|AAR21240.1| 345|Homo sapiens patched protein. 44 4e-04
AB209495-1|BAD92732.1| 586|Homo sapiens patched variant protein. 37 0.068
AL592166-13|CAI13008.1| 87|Homo sapiens patched homolog 2 (Dro... 35 0.36
>BC063302-1|AAH63302.1| 1278|Homo sapiens Niemann-Pick disease, type
C1 protein.
Length = 1278
Score = 99.5 bits (237), Expect = 1e-20
Identities = 53/120 (44%), Positives = 77/120 (64%), Gaps = 3/120 (2%)
Frame = -3
Query: 739 LMGVMXI-GIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPAD-ERVQDALQKIGST 566
+ GVM + GI L L S GI+ EFCSHI AF S + + ER ++AL +GS+
Sbjct: 1138 MFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSS 1197
Query: 565 VITGITFTNIP-IIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYLNNLRNK 389
V +GIT T I+VLAF+ +Q+ ++F+FRM+ +++LG HG++F PVLLSY+ NK
Sbjct: 1198 VFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNK 1257
>AF338230-1|AAK25791.1| 1278|Homo sapiens Niemann-Pick disease C1
protein protein.
Length = 1278
Score = 99.5 bits (237), Expect = 1e-20
Identities = 53/120 (44%), Positives = 77/120 (64%), Gaps = 3/120 (2%)
Frame = -3
Query: 739 LMGVMXI-GIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPAD-ERVQDALQKIGST 566
+ GVM + GI L L S GI+ EFCSHI AF S + + ER ++AL +GS+
Sbjct: 1138 MFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSS 1197
Query: 565 VITGITFTNIP-IIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYLNNLRNK 389
V +GIT T I+VLAF+ +Q+ ++F+FRM+ +++LG HG++F PVLLSY+ NK
Sbjct: 1198 VFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNK 1257
>AF157379-1|AAD48006.1| 1278|Homo sapiens Niemann-Pick C1 protein
protein.
Length = 1278
Score = 99.5 bits (237), Expect = 1e-20
Identities = 53/120 (44%), Positives = 77/120 (64%), Gaps = 3/120 (2%)
Frame = -3
Query: 739 LMGVMXI-GIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPAD-ERVQDALQKIGST 566
+ GVM + GI L L S GI+ EFCSHI AF S + + ER ++AL +GS+
Sbjct: 1138 MFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSS 1197
Query: 565 VITGITFTNIP-IIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYLNNLRNK 389
V +GIT T I+VLAF+ +Q+ ++F+FRM+ +++LG HG++F PVLLSY+ NK
Sbjct: 1198 VFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNK 1257
>AF002020-1|AAB63982.1| 1278|Homo sapiens Niemann-Pick C disease
protein protein.
Length = 1278
Score = 99.5 bits (237), Expect = 1e-20
Identities = 53/120 (44%), Positives = 77/120 (64%), Gaps = 3/120 (2%)
Frame = -3
Query: 739 LMGVMXI-GIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPAD-ERVQDALQKIGST 566
+ GVM + GI L L S GI+ EFCSHI AF S + + ER ++AL +GS+
Sbjct: 1138 MFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSS 1197
Query: 565 VITGITFTNIP-IIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYLNNLRNK 389
V +GIT T I+VLAF+ +Q+ ++F+FRM+ +++LG HG++F PVLLSY+ NK
Sbjct: 1198 VFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNK 1257
>AB209048-1|BAD92285.1| 1289|Homo sapiens Niemann-Pick disease, type
C1 variant protein.
Length = 1289
Score = 99.5 bits (237), Expect = 1e-20
Identities = 53/120 (44%), Positives = 77/120 (64%), Gaps = 3/120 (2%)
Frame = -3
Query: 739 LMGVMXI-GIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPAD-ERVQDALQKIGST 566
+ GVM + GI L L S GI+ EFCSHI AF S + + ER ++AL +GS+
Sbjct: 1149 MFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSS 1208
Query: 565 VITGITFTNIP-IIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYLNNLRNK 389
V +GIT T I+VLAF+ +Q+ ++F+FRM+ +++LG HG++F PVLLSY+ NK
Sbjct: 1209 VFSGITLTKFGGIVVLAFAKSQIFQIFYFRMYLAMVLLGATHGLIFLPVLLSYIGPSVNK 1268
>BC117178-1|AAI17179.1| 1332|Homo sapiens NPC1L1 protein protein.
Length = 1332
Score = 87.4 bits (207), Expect = 5e-17
Identities = 42/95 (44%), Positives = 64/95 (67%), Gaps = 2/95 (2%)
Frame = -3
Query: 685 LSCSIGIAGEFCSHIAYAFDSSTRPAD-ERVQDALQKIGSTVITGITFTNIP-IIVLAFS 512
L ++G++ EF SHI +F ST+P ER ++A +GS V G+ TN+P I+VL +
Sbjct: 1171 LVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLA 1230
Query: 511 YTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
Q+I++FFFR+ + +LG LHG+VF PV+LSY+
Sbjct: 1231 KAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYV 1265
>AY515256-1|AAS56939.1| 1332|Homo sapiens NPC1L1 splice variant
protein.
Length = 1332
Score = 87.4 bits (207), Expect = 5e-17
Identities = 42/95 (44%), Positives = 64/95 (67%), Gaps = 2/95 (2%)
Frame = -3
Query: 685 LSCSIGIAGEFCSHIAYAFDSSTRPAD-ERVQDALQKIGSTVITGITFTNIP-IIVLAFS 512
L ++G++ EF SHI +F ST+P ER ++A +GS V G+ TN+P I+VL +
Sbjct: 1171 LVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLA 1230
Query: 511 YTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
Q+I++FFFR+ + +LG LHG+VF PV+LSY+
Sbjct: 1231 KAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYV 1265
>AY437865-1|AAR97886.1| 1332|Homo sapiens Niemann-Pick C1-like 1
protein.
Length = 1332
Score = 87.4 bits (207), Expect = 5e-17
Identities = 42/95 (44%), Positives = 64/95 (67%), Gaps = 2/95 (2%)
Frame = -3
Query: 685 LSCSIGIAGEFCSHIAYAFDSSTRPAD-ERVQDALQKIGSTVITGITFTNIP-IIVLAFS 512
L ++G++ EF SHI +F ST+P ER ++A +GS V G+ TN+P I+VL +
Sbjct: 1171 LVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLA 1230
Query: 511 YTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
Q+I++FFFR+ + +LG LHG+VF PV+LSY+
Sbjct: 1231 KAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYV 1265
>AF192522-1|AAF20396.1| 1359|Homo sapiens Niemann-Pick C1-like protein
1 protein.
Length = 1359
Score = 87.4 bits (207), Expect = 5e-17
Identities = 42/95 (44%), Positives = 64/95 (67%), Gaps = 2/95 (2%)
Frame = -3
Query: 685 LSCSIGIAGEFCSHIAYAFDSSTRPAD-ERVQDALQKIGSTVITGITFTNIP-IIVLAFS 512
L ++G++ EF SHI +F ST+P ER ++A +GS V G+ TN+P I+VL +
Sbjct: 1198 LVSAVGMSVEFVSHITRSFAISTKPTWLERAKEATISMGSAVFAGVAMTNLPGILVLGLA 1257
Query: 511 YTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
Q+I++FFFR+ + +LG LHG+VF PV+LSY+
Sbjct: 1258 KAQLIQIFFFRLNLLITLLGLLHGLVFLPVILSYV 1292
>AF123046-1|AAF28875.1| 190|Homo sapiens Niemann-Pick C1 disease
protein protein.
Length = 190
Score = 69.3 bits (162), Expect = 1e-11
Identities = 40/92 (43%), Positives = 58/92 (63%), Gaps = 3/92 (3%)
Frame = -3
Query: 739 LMGVMXI-GIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPAD-ERVQDALQKIGST 566
+ GVM + GI L L S GI+ EFCSHI AF S + + ER ++AL +GS+
Sbjct: 97 MFGVMWLWGISLNAVSLVNLVMSCGISVEFCSHITRAFTVSMKGSRVERAEEALAHMGSS 156
Query: 565 VITGITFTNIP-IIVLAFSYTQVIEVFFFRMF 473
V +GIT T I+VLAF+ +Q+ ++F+FRM+
Sbjct: 157 VFSGITLTKFGGIVVLAFAKSQIFQIFYFRMY 188
>U59464-1|AAC50550.1| 1447|Homo sapiens PATCHED protein.
Length = 1447
Score = 63.3 bits (147), Expect = 9e-10
Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 1/111 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M IGI L L S+GI EF H+A AF ++ + R AL+ + + V
Sbjct: 1067 LFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPV 1126
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSY 410
+ G T + +++LA S I +FF + L ILG L+G+V PVLLS+
Sbjct: 1127 LDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSF 1177
>AL161729-2|CAH73818.1| 1296|Homo sapiens patched homolog 1
(Drosophila) protein.
Length = 1296
Score = 63.3 bits (147), Expect = 9e-10
Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 1/111 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M IGI L L S+GI EF H+A AF ++ + R AL+ + + V
Sbjct: 916 LFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPV 975
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSY 410
+ G T + +++LA S I +FF + L ILG L+G+V PVLLS+
Sbjct: 976 LDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSF 1026
>AL161729-1|CAH73817.1| 1447|Homo sapiens patched homolog 1
(Drosophila) protein.
Length = 1447
Score = 63.3 bits (147), Expect = 9e-10
Identities = 41/111 (36%), Positives = 60/111 (54%), Gaps = 1/111 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M IGI L L S+GI EF H+A AF ++ + R AL+ + + V
Sbjct: 1067 LFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPV 1126
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSY 410
+ G T + +++LA S I +FF + L ILG L+G+V PVLLS+
Sbjct: 1127 LDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTILGVLNGLVLLPVLLSF 1177
>AY438664-1|AAR05447.1| 1203|Homo sapiens patched homolog 2
(Drosophila) protein.
Length = 1203
Score = 62.9 bits (146), Expect = 1e-09
Identities = 40/112 (35%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M +GI L L S+GI EF H+A F ++ + R AL+ + V
Sbjct: 1003 LFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPV 1062
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
G T + +++LA S+ I +FF L +LG LHG+V PVLLS L
Sbjct: 1063 TDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSIL 1114
>AY359016-1|AAQ89375.1| 1203|Homo sapiens Patched 2 protein.
Length = 1203
Score = 62.9 bits (146), Expect = 1e-09
Identities = 40/112 (35%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M +GI L L S+GI EF H+A F ++ + R AL+ + V
Sbjct: 1003 LFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPV 1062
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
G T + +++LA S+ I +FF L +LG LHG+V PVLLS L
Sbjct: 1063 TDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSIL 1114
>AY358555-1|AAQ88919.1| 1211|Homo sapiens Patched 2 protein.
Length = 1211
Score = 62.9 bits (146), Expect = 1e-09
Identities = 40/112 (35%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M +GI L L S+GI EF H+A F ++ + R AL+ + V
Sbjct: 1003 LFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPV 1062
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
G T + +++LA S+ I +FF L +LG LHG+V PVLLS L
Sbjct: 1063 TDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSIL 1114
>AL592166-5|CAI13000.1| 1203|Homo sapiens patched homolog 2
(Drosophila) protein.
Length = 1203
Score = 62.9 bits (146), Expect = 1e-09
Identities = 40/112 (35%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M +GI L L S+GI EF H+A F ++ + R AL+ + V
Sbjct: 1003 LFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPV 1062
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
G T + +++LA S+ I +FF L +LG LHG+V PVLLS L
Sbjct: 1063 TDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSIL 1114
>AL136380-1|CAI23127.1| 1203|Homo sapiens patched homolog 2
(Drosophila) protein.
Length = 1203
Score = 62.9 bits (146), Expect = 1e-09
Identities = 40/112 (35%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M +GI L L S+GI EF H+A F ++ + R AL+ + V
Sbjct: 1003 LFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPV 1062
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
G T + +++LA S+ I +FF L +LG LHG+V PVLLS L
Sbjct: 1063 TDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSIL 1114
>AF119569-1|AAD17260.1| 1146|Homo sapiens patched 2 protein.
Length = 1146
Score = 62.9 bits (146), Expect = 1e-09
Identities = 40/112 (35%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M +GI L L S+GI EF H+A F ++ + R AL+ + V
Sbjct: 1003 LFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPV 1062
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
G T + +++LA S+ I +FF L +LG LHG+V PVLLS L
Sbjct: 1063 TDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSIL 1114
>AF091501-1|AAC79847.1| 1203|Homo sapiens receptor protein patched 2
protein.
Length = 1203
Score = 62.9 bits (146), Expect = 1e-09
Identities = 40/112 (35%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M +GI L L S+GI EF H+A F ++ + R AL+ + V
Sbjct: 1003 LFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPV 1062
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
G T + +++LA S+ I +FF L +LG LHG+V PVLLS L
Sbjct: 1063 TDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSIL 1114
>AF087651-1|AAD25953.1| 1203|Homo sapiens patched 2 protein.
Length = 1203
Score = 62.9 bits (146), Expect = 1e-09
Identities = 40/112 (35%), Positives = 57/112 (50%), Gaps = 1/112 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M +GI L L S+GI EF H+A F ++ + R AL+ + V
Sbjct: 1003 LFGIMGFLGIKLSAIPVVILVASVGIGVEFTVHVALGFLTTQGSRNLRAAHALEHTFAPV 1062
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSYL 407
G T + +++LA S+ I +FF L +LG LHG+V PVLLS L
Sbjct: 1063 TDGAISTLLGLLMLAGSHFDFIVRYFFAALTVLTLLGLLHGLVLLPVLLSIL 1114
>U43148-1|AAC50496.1| 1296|Homo sapiens PTC protein.
Length = 1296
Score = 60.9 bits (141), Expect = 5e-09
Identities = 40/111 (36%), Positives = 59/111 (53%), Gaps = 1/111 (0%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M IGI L L S+GI EF H+A AF ++ + R AL+ + + V
Sbjct: 916 LFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAISDKNRRAVLALEHMFAPV 975
Query: 562 ITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIILGFLHGMVFFPVLLSY 410
+ G T + +++LA S I +FF + L ILG L+G+V PVL S+
Sbjct: 976 LDGAVSTLLGVLMLAGSDFDFIVRYFFAVLAILTILGVLNGLVLLPVLWSF 1026
>AY395772-1|AAR21240.1| 345|Homo sapiens patched protein.
Length = 345
Score = 44.4 bits (100), Expect = 4e-04
Identities = 26/75 (34%), Positives = 42/75 (56%)
Frame = -3
Query: 634 AFDSSTRPADERVQDALQKIGSTVITGITFTNIPIIVLAFSYTQVIEVFFFRMFFTLIIL 455
AF ++ + R AL+ + + V+ G T + +++LA S I +FF + L IL
Sbjct: 1 AFLTAIGDKNRRAVLALEHMFAPVLDGAVSTLLGVLMLAGSEFDFIVRYFFAVLAILTIL 60
Query: 454 GFLHGMVFFPVLLSY 410
G L+G+V PVLLS+
Sbjct: 61 GVLNGLVLLPVLLSF 75
>AB209495-1|BAD92732.1| 586|Homo sapiens patched variant protein.
Length = 586
Score = 37.1 bits (82), Expect = 0.068
Identities = 26/77 (33%), Positives = 40/77 (51%), Gaps = 1/77 (1%)
Frame = -3
Query: 739 LMGVMX-IGIFLKRCVXC*LSCSIGIAGEFCSHIAYAFDSSTRPADERVQDALQKIGSTV 563
L G+M IGI L L S+GI EF H+A AF ++ + R AL+ + + V
Sbjct: 503 LFGMMGLIGIKLSAVPVVILIASVGIGVEFTVHVALAFLTAIGDKNRRAVLALEHMFAPV 562
Query: 562 ITGITFTNIPIIVLAFS 512
+ G T + +++LA S
Sbjct: 563 LDGAVSTLLGVLMLAGS 579
>AL592166-13|CAI13008.1| 87|Homo sapiens patched homolog 2
(Drosophila) protein.
Length = 87
Score = 34.7 bits (76), Expect = 0.36
Identities = 15/28 (53%), Positives = 18/28 (64%)
Frame = -3
Query: 490 FFFRMFFTLIILGFLHGMVFFPVLLSYL 407
+FF L +LG LHG+V PVLLS L
Sbjct: 7 YFFAALTVLTLLGLLHGLVLLPVLLSIL 34
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 89,354,575
Number of Sequences: 237096
Number of extensions: 1707586
Number of successful extensions: 2765
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 2672
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2751
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 9127122082
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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