Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV13d21f
(641 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
AF338230-1|AAK25791.1| 1278|Homo sapiens Niemann-Pick disease C1... 65 2e-10
AF157379-1|AAD48006.1| 1278|Homo sapiens Niemann-Pick C1 protein... 65 2e-10
AF002020-1|AAB63982.1| 1278|Homo sapiens Niemann-Pick C disease ... 65 2e-10
AB209048-1|BAD92285.1| 1289|Homo sapiens Niemann-Pick disease, t... 65 2e-10
BC063302-1|AAH63302.1| 1278|Homo sapiens Niemann-Pick disease, t... 64 3e-10
BC117178-1|AAI17179.1| 1332|Homo sapiens NPC1L1 protein protein. 60 5e-09
AY515256-1|AAS56939.1| 1332|Homo sapiens NPC1L1 splice variant p... 60 5e-09
AY437865-1|AAR97886.1| 1332|Homo sapiens Niemann-Pick C1-like 1 ... 60 5e-09
AF192523-1|AAF20397.1| 724|Homo sapiens truncated Niemann-Pick ... 60 5e-09
AF192522-1|AAF20396.1| 1359|Homo sapiens Niemann-Pick C1-like pr... 60 5e-09
M64594-1|AAA63230.1| 610|Homo sapiens mucin protein. 33 0.86
>AF338230-1|AAK25791.1| 1278|Homo sapiens Niemann-Pick disease C1
protein protein.
Length = 1278
Score = 64.9 bits (151), Expect = 2e-10
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Frame = +2
Query: 320 FNEILTCCEPVQIRKLSESLMLADGILGRCPTCLRNFARQICEMNCSPDQSRFVDV---- 487
F + CC+ Q++ L ++L L L RCP+C N CE+ CSP QS+F++V
Sbjct: 68 FGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATE 127
Query: 488 -YTE-VSGGVR-YVNEIDYRLYEPFMLGAHASCAGVIIPQTGLPAINMMCG 631
Y + V+ + V E+ Y + + F + +C V P + A+ ++CG
Sbjct: 128 DYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCG 178
>AF157379-1|AAD48006.1| 1278|Homo sapiens Niemann-Pick C1 protein
protein.
Length = 1278
Score = 64.9 bits (151), Expect = 2e-10
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Frame = +2
Query: 320 FNEILTCCEPVQIRKLSESLMLADGILGRCPTCLRNFARQICEMNCSPDQSRFVDV---- 487
F + CC+ Q++ L ++L L L RCP+C N CE+ CSP QS+F++V
Sbjct: 68 FGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATE 127
Query: 488 -YTE-VSGGVR-YVNEIDYRLYEPFMLGAHASCAGVIIPQTGLPAINMMCG 631
Y + V+ + V E+ Y + + F + +C V P + A+ ++CG
Sbjct: 128 DYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCG 178
>AF002020-1|AAB63982.1| 1278|Homo sapiens Niemann-Pick C disease
protein protein.
Length = 1278
Score = 64.9 bits (151), Expect = 2e-10
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Frame = +2
Query: 320 FNEILTCCEPVQIRKLSESLMLADGILGRCPTCLRNFARQICEMNCSPDQSRFVDV---- 487
F + CC+ Q++ L ++L L L RCP+C N CE+ CSP QS+F++V
Sbjct: 68 FGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATE 127
Query: 488 -YTE-VSGGVR-YVNEIDYRLYEPFMLGAHASCAGVIIPQTGLPAINMMCG 631
Y + V+ + V E+ Y + + F + +C V P + A+ ++CG
Sbjct: 128 DYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCG 178
>AB209048-1|BAD92285.1| 1289|Homo sapiens Niemann-Pick disease, type
C1 variant protein.
Length = 1289
Score = 64.9 bits (151), Expect = 2e-10
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Frame = +2
Query: 320 FNEILTCCEPVQIRKLSESLMLADGILGRCPTCLRNFARQICEMNCSPDQSRFVDV---- 487
F + CC+ Q++ L ++L L L RCP+C N CE+ CSP QS+F++V
Sbjct: 79 FGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATE 138
Query: 488 -YTE-VSGGVR-YVNEIDYRLYEPFMLGAHASCAGVIIPQTGLPAINMMCG 631
Y + V+ + V E+ Y + + F + +C V P + A+ ++CG
Sbjct: 139 DYVDPVTNQTKTNVKELQYYVGQSFANAMYNACRDVEAPSSNDKALGLLCG 189
>BC063302-1|AAH63302.1| 1278|Homo sapiens Niemann-Pick disease, type
C1 protein.
Length = 1278
Score = 64.5 bits (150), Expect = 3e-10
Identities = 34/111 (30%), Positives = 57/111 (51%), Gaps = 7/111 (6%)
Frame = +2
Query: 320 FNEILTCCEPVQIRKLSESLMLADGILGRCPTCLRNFARQICEMNCSPDQSRFVDV---- 487
F + CC+ Q++ L ++L L L RCP+C N CE+ CSP QS+F++V
Sbjct: 68 FGNVSLCCDVRQLQTLKDNLQLPLQFLSRCPSCFYNLLNLFCELTCSPRQSQFLNVTATE 127
Query: 488 -YTE-VSGGVR-YVNEIDYRLYEPFMLGAHASCAGVIIPQTGLPAINMMCG 631
Y + V+ + V E+ Y + + F + +C V P + A+ ++CG
Sbjct: 128 DYVDPVTNQTKTNVKELQYYVGQGFANAMYNACRDVEAPSSNDKALGLLCG 178
>BC117178-1|AAI17179.1| 1332|Homo sapiens NPC1L1 protein protein.
Length = 1332
Score = 60.5 bits (140), Expect = 5e-09
Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 4/102 (3%)
Frame = +2
Query: 338 CCEPVQIRKLSESLMLADGILGRCPTCLRNFARQICEMNCSPDQSRFVDVYTEVS--GGV 511
CC Q+ L SL + +L RCP C NF C CSP+QS F++V T V+ G
Sbjct: 90 CCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINV-TRVAQLGAG 148
Query: 512 RYVNEIDYRLY--EPFMLGAHASCAGVIIPQTGLPAINMMCG 631
+ + Y + F ++ SC+ V +P A+ MCG
Sbjct: 149 QLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCG 190
>AY515256-1|AAS56939.1| 1332|Homo sapiens NPC1L1 splice variant
protein.
Length = 1332
Score = 60.5 bits (140), Expect = 5e-09
Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 4/102 (3%)
Frame = +2
Query: 338 CCEPVQIRKLSESLMLADGILGRCPTCLRNFARQICEMNCSPDQSRFVDVYTEVS--GGV 511
CC Q+ L SL + +L RCP C NF C CSP+QS F++V T V+ G
Sbjct: 90 CCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINV-TRVAQLGAG 148
Query: 512 RYVNEIDYRLY--EPFMLGAHASCAGVIIPQTGLPAINMMCG 631
+ + Y + F ++ SC+ V +P A+ MCG
Sbjct: 149 QLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCG 190
>AY437865-1|AAR97886.1| 1332|Homo sapiens Niemann-Pick C1-like 1
protein.
Length = 1332
Score = 60.5 bits (140), Expect = 5e-09
Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 4/102 (3%)
Frame = +2
Query: 338 CCEPVQIRKLSESLMLADGILGRCPTCLRNFARQICEMNCSPDQSRFVDVYTEVS--GGV 511
CC Q+ L SL + +L RCP C NF C CSP+QS F++V T V+ G
Sbjct: 90 CCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINV-TRVAQLGAG 148
Query: 512 RYVNEIDYRLY--EPFMLGAHASCAGVIIPQTGLPAINMMCG 631
+ + Y + F ++ SC+ V +P A+ MCG
Sbjct: 149 QLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCG 190
>AF192523-1|AAF20397.1| 724|Homo sapiens truncated Niemann-Pick
C1-like protein 1 protein.
Length = 724
Score = 60.5 bits (140), Expect = 5e-09
Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 4/102 (3%)
Frame = +2
Query: 338 CCEPVQIRKLSESLMLADGILGRCPTCLRNFARQICEMNCSPDQSRFVDVYTEVS--GGV 511
CC Q+ L SL + +L RCP C NF C CSP+QS F++V T V+ G
Sbjct: 90 CCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINV-TRVAQLGAG 148
Query: 512 RYVNEIDYRLY--EPFMLGAHASCAGVIIPQTGLPAINMMCG 631
+ + Y + F ++ SC+ V +P A+ MCG
Sbjct: 149 QLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCG 190
>AF192522-1|AAF20396.1| 1359|Homo sapiens Niemann-Pick C1-like
protein 1 protein.
Length = 1359
Score = 60.5 bits (140), Expect = 5e-09
Identities = 34/102 (33%), Positives = 49/102 (48%), Gaps = 4/102 (3%)
Frame = +2
Query: 338 CCEPVQIRKLSESLMLADGILGRCPTCLRNFARQICEMNCSPDQSRFVDVYTEVS--GGV 511
CC Q+ L SL + +L RCP C NF C CSP+QS F++V T V+ G
Sbjct: 90 CCSAKQLVSLEASLSITKALLTRCPACSDNFVNLHCHNTCSPNQSLFINV-TRVAQLGAG 148
Query: 512 RYVNEIDYRLY--EPFMLGAHASCAGVIIPQTGLPAINMMCG 631
+ + Y + F ++ SC+ V +P A+ MCG
Sbjct: 149 QLPAVVAYEAFYQHSFAEQSYDSCSRVRVPAAATLAVGTMCG 190
>M64594-1|AAA63230.1| 610|Homo sapiens mucin protein.
Length = 610
Score = 33.1 bits (72), Expect = 0.86
Identities = 22/56 (39%), Positives = 29/56 (51%), Gaps = 3/56 (5%)
Frame = -3
Query: 300 SSKTRLGHLSVKMSTI-SSASAGDSPS--TTGLASISTGQGFAWPAISMHSPRNRH 142
+S GH + TI SSAS+GD+ S T L+S+STG P S+ S H
Sbjct: 257 ASSVSTGHATSLPVTIPSSASSGDATSLPVTSLSSLSTGHATPLPVTSLSSASTGH 312
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 93,051,764
Number of Sequences: 237096
Number of extensions: 1904073
Number of successful extensions: 6055
Number of sequences better than 10.0: 11
Number of HSP's better than 10.0 without gapping: 5915
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6050
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7085195460
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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