Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV13d08r
(686 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 166 7e-41
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 166 7e-41
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 166 7e-41
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 166 7e-41
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 165 2e-40
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 162 9e-40
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 157 3e-38
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 157 3e-38
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 157 3e-38
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 133 5e-31
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 129 8e-30
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 90 6e-18
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 90 6e-18
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 90 6e-18
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 77 8e-14
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 77 8e-14
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 77 8e-14
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 75 3e-13
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 75 3e-13
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 75 3e-13
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 75 3e-13
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 75 3e-13
BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein. 56 9e-08
CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein. 31 3.8
U83246-1|AAC15920.1| 537|Homo sapiens copine I protein. 31 5.1
BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein. 31 5.1
AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein. 31 5.1
AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein. 31 5.1
AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein. 31 5.1
AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein. 31 5.1
AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation ... 30 6.7
AF103671-1|AAD16731.1| 106|Homo sapiens immunoglobulin lambda l... 30 8.9
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 166 bits (403), Expect = 7e-41
Identities = 75/200 (37%), Positives = 121/200 (60%), Gaps = 1/200 (0%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
++A S + GYP +RLP+ +EEE+ +I+GTADFF V +YT L+ ++ + + +
Sbjct: 271 QIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQEN--KKGELGILQ 328
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLED 325
D + + P W W+ ++P + +L ++K+ YN+P+ Y+TENG+ S L+D
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 324 DDRITYYRAALENILDSLDAG-VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARP 148
R Y+R + + ++ V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARP
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 147 RTPRKSAFVYKEILRSRVID 88
R P SA Y +I+R+ ++
Sbjct: 447 RVPYTSAKEYAKIIRNNGLE 466
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 166 bits (403), Expect = 7e-41
Identities = 75/200 (37%), Positives = 121/200 (60%), Gaps = 1/200 (0%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
++A S + GYP +RLP+ +EEE+ +I+GTADFF V +YT L+ ++ + + +
Sbjct: 271 QIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQEN--KKGELGILQ 328
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLED 325
D + + P W W+ ++P + +L ++K+ YN+P+ Y+TENG+ S L+D
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 324 DDRITYYRAALENILDSLDAG-VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARP 148
R Y+R + + ++ V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARP
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 147 RTPRKSAFVYKEILRSRVID 88
R P SA Y +I+R+ ++
Sbjct: 447 RVPYTSAKEYAKIIRNNGLE 466
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 166 bits (403), Expect = 7e-41
Identities = 75/200 (37%), Positives = 121/200 (60%), Gaps = 1/200 (0%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
++A S + GYP +RLP+ +EEE+ +I+GTADFF V +YT L+ ++ + + +
Sbjct: 271 QIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQEN--KKGELGILQ 328
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLED 325
D + + P W W+ ++P + +L ++K+ YN+P+ Y+TENG+ S L+D
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 324 DDRITYYRAALENILDSLDAG-VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARP 148
R Y+R + + ++ V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARP
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 147 RTPRKSAFVYKEILRSRVID 88
R P SA Y +I+R+ ++
Sbjct: 447 RVPYTSAKEYAKIIRNNGLE 466
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 166 bits (403), Expect = 7e-41
Identities = 75/200 (37%), Positives = 121/200 (60%), Gaps = 1/200 (0%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
++A S + GYP +RLP+ +EEE+ +I+GTADFF V +YT L+ ++ + + +
Sbjct: 271 QIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQEN--KKGELGILQ 328
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLED 325
D + + P W W+ ++P + +L ++K+ YN+P+ Y+TENG+ S L+D
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 324 DDRITYYRAALENILDSLDAG-VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARP 148
R Y+R + + ++ V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARP
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 147 RTPRKSAFVYKEILRSRVID 88
R P SA Y +I+R+ ++
Sbjct: 447 RVPYTSAKEYAKIIRNNGLE 466
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 165 bits (400), Expect = 2e-40
Identities = 75/200 (37%), Positives = 120/200 (60%), Gaps = 1/200 (0%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
++A S + GYP +RLP+ +EEE+ +I+GTADFF V +YT L+ ++ + +
Sbjct: 271 QIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQEN--KKGELGTLQ 328
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLED 325
D + + P W W+ ++P + +L ++K+ YN+P+ Y+TENG+ S L+D
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 324 DDRITYYRAALENILDSLDAG-VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARP 148
R Y+R + + ++ V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARP
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 147 RTPRKSAFVYKEILRSRVID 88
R P SA Y +I+R+ ++
Sbjct: 447 RVPYTSAKEYAKIIRNNGLE 466
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 162 bits (394), Expect = 9e-40
Identities = 74/200 (37%), Positives = 120/200 (60%), Gaps = 1/200 (0%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
++A S + GYP +RLP+ +EEE+ +I+GTADFF V + T L+ ++ + + +
Sbjct: 271 QIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYCTTRLIKYQEN--KRGELGILQ 328
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLED 325
D + + P W W+ ++P + +L ++K+ YN+P+ Y+TENG+ S L+D
Sbjct: 329 DAEIEFFPDPSWKN--VDWIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDD 386
Query: 324 DDRITYYRAALENILDSLDAG-VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARP 148
R Y+R + + ++ V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARP
Sbjct: 387 TQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARP 446
Query: 147 RTPRKSAFVYKEILRSRVID 88
R P SA Y +I+R+ ++
Sbjct: 447 RVPYTSAKEYAKIIRNNGLE 466
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 157 bits (382), Expect = 3e-38
Identities = 78/194 (40%), Positives = 108/194 (55%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
R+ ++S G ++RLP+ +E E+ I GT DFFG NHYT L + S S +
Sbjct: 1645 RIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAIS--SFDA 1702
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLED 325
D V + W S + WL + P +L LK +YNDP YVTENG + E L D
Sbjct: 1703 DRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLND 1762
Query: 324 DDRITYYRAALENILDSLDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPR 145
RI Y R + L ++ V L+GY WS MDN+EW G++ERFGL+ V++SDP+ PR
Sbjct: 1763 TARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPR 1822
Query: 144 TPRKSAFVYKEILR 103
P+ SA Y ++R
Sbjct: 1823 IPKASAKFYASVVR 1836
Score = 129 bits (312), Expect = 8e-30
Identities = 76/196 (38%), Positives = 106/196 (54%), Gaps = 3/196 (1%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
+V +S +RLP +EEE+ IR TAD F +N Y +V P + S
Sbjct: 1171 KVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQ--HKTPRLNPPSYED 1228
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWA-TSPEVGLE 328
D + P W +A + P +L +K +Y D Y+TENG T+P E
Sbjct: 1229 DQEMAEEEDPSWPSTAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNT--E 1284
Query: 327 DDDRITYYRAALENILDS--LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPA 154
D DRI Y++ + L + LD G+ L+GY+AWSLMDN+EW+ GYT +FGLY VDF++
Sbjct: 1285 DTDRIFYHKTYINEALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTN 1343
Query: 153 RPRTPRKSAFVYKEIL 106
RPRT R SA Y E++
Sbjct: 1344 RPRTARASARYYTEVI 1359
Score = 120 bits (289), Expect = 5e-27
Identities = 67/201 (33%), Positives = 118/201 (58%), Gaps = 8/201 (3%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKH---IPEYSTVS 514
++ + + + +P +LP+ +E E+ L++G+ADF G++HYT L+S IP Y T+
Sbjct: 648 QIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIG 707
Query: 513 LFSDINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYND---PIFYVTENGWATSP 343
FS +V + W Q+++SW+ ++P I +L + +Y PI Y+ NG
Sbjct: 708 GFSQ-HVNHV----WPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGE 761
Query: 342 EVGLEDDD-RITYYRAALENILDSL-DAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVD 169
L DD R+ Y+ + +L ++ + V ++ Y+A SL+D +E +GY++RFGL+ V+
Sbjct: 762 SENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVN 821
Query: 168 FSDPARPRTPRKSAFVYKEIL 106
FSD ++ RTPRKSA+ + I+
Sbjct: 822 FSDSSKSRTPRKSAYFFTSII 842
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 157 bits (382), Expect = 3e-38
Identities = 78/194 (40%), Positives = 108/194 (55%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
R+ ++S G ++RLP+ +E E+ I GT DFFG NHYT L + S S +
Sbjct: 1645 RIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAIS--SFDA 1702
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLED 325
D V + W S + WL + P +L LK +YNDP YVTENG + E L D
Sbjct: 1703 DRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLND 1762
Query: 324 DDRITYYRAALENILDSLDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPR 145
RI Y R + L ++ V L+GY WS MDN+EW G++ERFGL+ V++SDP+ PR
Sbjct: 1763 TARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPR 1822
Query: 144 TPRKSAFVYKEILR 103
P+ SA Y ++R
Sbjct: 1823 IPKASAKFYASVVR 1836
Score = 129 bits (312), Expect = 8e-30
Identities = 76/196 (38%), Positives = 106/196 (54%), Gaps = 3/196 (1%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
+V +S +RLP +EEE+ IR TAD F +N Y +V P + S
Sbjct: 1171 KVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQ--HKTPRLNPPSYED 1228
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWA-TSPEVGLE 328
D + P W +A + P +L +K +Y D Y+TENG T+P E
Sbjct: 1229 DQEMAEEEDPSWPSTAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNT--E 1284
Query: 327 DDDRITYYRAALENILDS--LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPA 154
D DRI Y++ + L + LD G+ L+GY+AWSLMDN+EW+ GYT +FGLY VDF++
Sbjct: 1285 DTDRIFYHKTYINEALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTN 1343
Query: 153 RPRTPRKSAFVYKEIL 106
RPRT R SA Y E++
Sbjct: 1344 RPRTARASARYYTEVI 1359
Score = 120 bits (289), Expect = 5e-27
Identities = 67/201 (33%), Positives = 118/201 (58%), Gaps = 8/201 (3%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKH---IPEYSTVS 514
++ + + + +P +LP+ +E E+ L++G+ADF G++HYT L+S IP Y T+
Sbjct: 648 QIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIG 707
Query: 513 LFSDINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYND---PIFYVTENGWATSP 343
FS +V + W Q+++SW+ ++P I +L + +Y PI Y+ NG
Sbjct: 708 GFSQ-HVNHV----WPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGE 761
Query: 342 EVGLEDDD-RITYYRAALENILDSL-DAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVD 169
L DD R+ Y+ + +L ++ + V ++ Y+A SL+D +E +GY++RFGL+ V+
Sbjct: 762 SENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVN 821
Query: 168 FSDPARPRTPRKSAFVYKEIL 106
FSD ++ RTPRKSA+ + I+
Sbjct: 822 FSDSSKSRTPRKSAYFFTSII 842
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 157 bits (382), Expect = 3e-38
Identities = 78/194 (40%), Positives = 108/194 (55%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
R+ ++S G ++RLP+ +E E+ I GT DFFG NHYT L + S S +
Sbjct: 1645 RIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAIS--SFDA 1702
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLED 325
D V + W S + WL + P +L LK +YNDP YVTENG + E L D
Sbjct: 1703 DRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLND 1762
Query: 324 DDRITYYRAALENILDSLDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPR 145
RI Y R + L ++ V L+GY WS MDN+EW G++ERFGL+ V++SDP+ PR
Sbjct: 1763 TARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPR 1822
Query: 144 TPRKSAFVYKEILR 103
P+ SA Y ++R
Sbjct: 1823 IPKASAKFYASVVR 1836
Score = 129 bits (312), Expect = 8e-30
Identities = 76/196 (38%), Positives = 106/196 (54%), Gaps = 3/196 (1%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
+V +S +RLP +EEE+ IR TAD F +N Y +V P + S
Sbjct: 1171 KVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQ--HKTPRLNPPSYED 1228
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWA-TSPEVGLE 328
D + P W +A + P +L +K +Y D Y+TENG T+P E
Sbjct: 1229 DQEMAEEEDPSWPSTAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNT--E 1284
Query: 327 DDDRITYYRAALENILDS--LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPA 154
D DRI Y++ + L + LD G+ L+GY+AWSLMDN+EW+ GYT +FGLY VDF++
Sbjct: 1285 DTDRIFYHKTYINEALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTN 1343
Query: 153 RPRTPRKSAFVYKEIL 106
RPRT R SA Y E++
Sbjct: 1344 RPRTARASARYYTEVI 1359
Score = 120 bits (289), Expect = 5e-27
Identities = 67/201 (33%), Positives = 118/201 (58%), Gaps = 8/201 (3%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKH---IPEYSTVS 514
++ + + + +P +LP+ +E E+ L++G+ADF G++HYT L+S IP Y T+
Sbjct: 648 QIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIG 707
Query: 513 LFSDINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYND---PIFYVTENGWATSP 343
FS +V + W Q+++SW+ ++P I +L + +Y PI Y+ NG
Sbjct: 708 GFSQ-HVNHV----WPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGE 761
Query: 342 EVGLEDDD-RITYYRAALENILDSL-DAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVD 169
L DD R+ Y+ + +L ++ + V ++ Y+A SL+D +E +GY++RFGL+ V+
Sbjct: 762 SENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVN 821
Query: 168 FSDPARPRTPRKSAFVYKEIL 106
FSD ++ RTPRKSA+ + I+
Sbjct: 822 FSDSSKSRTPRKSAYFFTSII 842
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 133 bits (322), Expect = 5e-31
Identities = 66/193 (34%), Positives = 106/193 (54%), Gaps = 1/193 (0%)
Frame = -3
Query: 681 VAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSD 502
+ KSAE G +RLP S +E+ I+GT+DF G+ H+T ++ ++ P S +D
Sbjct: 307 IGRKSAEQGLEMSRLPVFSLQEKSYIKGTSDFLGLGHFTTRYITE-RNYPSRQGPSYQND 365
Query: 501 INVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPE-VGLED 325
++ P W + WL +P +L + +Y DP YV ENG + L D
Sbjct: 366 RDLIELVDPNWPDLGSKWLYSVPWGFRRLLNFAQTQYGDPPIYVMENGASQKFHCTQLCD 425
Query: 324 DDRITYYRAALENILDSLDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPR 145
+ RI Y + + +L ++ G +KGY +WSL+D +EW GY++R+G Y V+F+D +PR
Sbjct: 426 EWRIQYLKGYINEMLKAIKDGANIKGYTSWSLLDKFEWEKGYSDRYGFYYVEFNDRNKPR 485
Query: 144 TPRKSAFVYKEIL 106
P+ S YK+I+
Sbjct: 486 YPKASVQYYKKII 498
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 129 bits (312), Expect = 8e-30
Identities = 76/196 (38%), Positives = 106/196 (54%), Gaps = 3/196 (1%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFS 505
+V +S +RLP +EEE+ IR TAD F +N Y +V P + S
Sbjct: 603 KVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQ--HKTPRLNPPSYED 660
Query: 504 DINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWA-TSPEVGLE 328
D + P W +A + P +L +K +Y D Y+TENG T+P E
Sbjct: 661 DQEMAEEEDPSWPSTAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPNT--E 716
Query: 327 DDDRITYYRAALENILDS--LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPA 154
D DRI Y++ + L + LD G+ L+GY+AWSLMDN+EW+ GYT +FGLY VDF++
Sbjct: 717 DTDRIFYHKTYINEALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTN 775
Query: 153 RPRTPRKSAFVYKEIL 106
RPRT R SA Y E++
Sbjct: 776 RPRTARASARYYTEVI 791
Score = 120 bits (289), Expect = 5e-27
Identities = 67/201 (33%), Positives = 118/201 (58%), Gaps = 8/201 (3%)
Frame = -3
Query: 684 RVAEKSAEHGYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKH---IPEYSTVS 514
++ + + + +P +LP+ +E E+ L++G+ADF G++HYT L+S IP Y T+
Sbjct: 80 QIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIG 139
Query: 513 LFSDINVGNYRPPEWLQSAASWLTLMPNSIYDVLTHLKNKYND---PIFYVTENGWATSP 343
FS +V + W Q+++SW+ ++P I +L + +Y PI Y+ NG
Sbjct: 140 GFSQ-HVNHV----WPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGE 193
Query: 342 EVGLEDDD-RITYYRAALENILDSL-DAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVD 169
L DD R+ Y+ + +L ++ + V ++ Y+A SL+D +E +GY++RFGL+ V+
Sbjct: 194 SENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVN 253
Query: 168 FSDPARPRTPRKSAFVYKEIL 106
FSD ++ RTPRKSA+ + I+
Sbjct: 254 FSDSSKSRTPRKSAYFFTSII 274
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 90.2 bits (214), Expect = 6e-18
Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 1/110 (0%)
Frame = -3
Query: 429 SIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VRL 253
++ + L +K +YN+P + ENGW T V ED I + L +L ++ +R+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 252 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 103
GY AWSL+D +EW YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 56.4 bits (130), Expect = 9e-08
Identities = 48/166 (28%), Positives = 76/166 (45%), Gaps = 2/166 (1%)
Frame = -3
Query: 657 GYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRP 478
G + LP+L+E ER L++GT DF +NH+T V + E S + +
Sbjct: 797 GLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFV-----MHEQLAGSRYDSDRDIQFLQ 851
Query: 477 PEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRA 298
S+ + L ++P + +L ++ Y D Y+T +G + LEDD YY
Sbjct: 852 DITRLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASG---IDDQALEDDRLRKYYLG 908
Query: 297 A-LENILDS-LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDF 166
L+ +L + L VR+KGY A+ L + RFG + DF
Sbjct: 909 KYLQEVLKAYLIDKVRIKGYYAFKLAEEKS-----KPRFGFFTSDF 949
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 90.2 bits (214), Expect = 6e-18
Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 1/110 (0%)
Frame = -3
Query: 429 SIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VRL 253
++ + L +K +YN+P + ENGW T V ED I + L +L ++ +R+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 252 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 103
GY AWSL+D +EW YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 56.4 bits (130), Expect = 9e-08
Identities = 48/166 (28%), Positives = 76/166 (45%), Gaps = 2/166 (1%)
Frame = -3
Query: 657 GYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRP 478
G + LP+L+E ER L++GT DF +NH+T V + E S + +
Sbjct: 797 GLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFV-----MHEQLAGSRYDSDRDIQFLQ 851
Query: 477 PEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRA 298
S+ + L ++P + +L ++ Y D Y+T +G + LEDD YY
Sbjct: 852 DITRLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASG---IDDQALEDDRLRKYYLG 908
Query: 297 A-LENILDS-LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDF 166
L+ +L + L VR+KGY A+ L + RFG + DF
Sbjct: 909 KYLQEVLKAYLIDKVRIKGYYAFKLAEEKS-----KPRFGFFTSDF 949
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 90.2 bits (214), Expect = 6e-18
Identities = 42/110 (38%), Positives = 63/110 (57%), Gaps = 1/110 (0%)
Frame = -3
Query: 429 SIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENILDSLDAG-VRL 253
++ + L +K +YN+P + ENGW T V ED I + L +L ++ +R+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 252 KGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILR 103
GY AWSL+D +EW YT R GL+ VDF+ + R P+ SA YK+I+R
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 56.4 bits (130), Expect = 9e-08
Identities = 48/166 (28%), Positives = 76/166 (45%), Gaps = 2/166 (1%)
Frame = -3
Query: 657 GYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRP 478
G + LP+L+E ER L++GT DF +NH+T V + E S + +
Sbjct: 797 GLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFV-----MHEQLAGSRYDSDRDIQFLQ 851
Query: 477 PEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRA 298
S+ + L ++P + +L ++ Y D Y+T +G + LEDD YY
Sbjct: 852 DITRLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASG---IDDQALEDDRLRKYYLG 908
Query: 297 A-LENILDS-LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDF 166
L+ +L + L VR+KGY A+ L + RFG + DF
Sbjct: 909 KYLQEVLKAYLIDKVRIKGYYAFKLAEEKS-----KPRFGFFTSDF 949
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 76.6 bits (180), Expect = 8e-14
Identities = 32/58 (55%), Positives = 42/58 (72%)
Frame = -3
Query: 261 VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 88
V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 76.6 bits (180), Expect = 8e-14
Identities = 32/58 (55%), Positives = 42/58 (72%)
Frame = -3
Query: 261 VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 88
V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 76.6 bits (180), Expect = 8e-14
Identities = 32/58 (55%), Positives = 42/58 (72%)
Frame = -3
Query: 261 VRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEILRSRVID 88
V L+ Y AWSL+DN+EW GY+ RFGL+ VDF DPARPR P SA Y +I+R+ ++
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 74.5 bits (175), Expect = 3e-13
Identities = 54/179 (30%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = -3
Query: 639 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 460
LP +E E+ I+GTADFF A P S L + P L+
Sbjct: 76 LPDFTESEKKFIKGTADFF-----------ALCFGPTLSFQLLDPHMKFRQLESPN-LRQ 123
Query: 459 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENIL 280
SW+ L ++N P ++ ENGW S +D + Y + + L
Sbjct: 124 LLSWIDL--------------EFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETL 169
Query: 279 DSLDA-GVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 106
++ GV + GY AWSLMD +EW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 170 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 228
Score = 66.9 bits (156), Expect = 6e-11
Identities = 59/183 (32%), Positives = 85/183 (46%), Gaps = 3/183 (1%)
Frame = -3
Query: 639 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 460
LP +E+E+ LI+GT DF ++HYT LV + K P + + V WL S
Sbjct: 513 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDP----IKYNDYLEVQEMTDITWLNS 568
Query: 459 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENI 283
S + ++P + VL LK KY D Y+ NG + EDD R+ Y + +
Sbjct: 569 -PSQVAVVPWGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEA 625
Query: 282 LDS--LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEI 109
L + LD G+ L GY A+S D RFGLY +D P+ K Y++I
Sbjct: 626 LKAHILD-GINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKI 674
Query: 108 LRS 100
+ S
Sbjct: 675 IDS 677
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 74.5 bits (175), Expect = 3e-13
Identities = 54/179 (30%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = -3
Query: 639 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 460
LP +E E+ I+GTADFF A P S L + P L+
Sbjct: 349 LPDFTESEKKFIKGTADFF-----------ALCFGPTLSFQLLDPHMKFRQLESPN-LRQ 396
Query: 459 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENIL 280
SW+ L ++N P ++ ENGW S +D + Y + + L
Sbjct: 397 LLSWIDL--------------EFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETL 442
Query: 279 DSLDA-GVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 106
++ GV + GY AWSLMD +EW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 443 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 66.9 bits (156), Expect = 6e-11
Identities = 59/183 (32%), Positives = 85/183 (46%), Gaps = 3/183 (1%)
Frame = -3
Query: 639 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 460
LP +E+E+ LI+GT DF ++HYT LV + K P + + V WL S
Sbjct: 786 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDP----IKYNDYLEVQEMTDITWLNS 841
Query: 459 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENI 283
S + ++P + VL LK KY D Y+ NG + EDD R+ Y + +
Sbjct: 842 -PSQVAVVPWGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEA 898
Query: 282 LDS--LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEI 109
L + LD G+ L GY A+S D RFGLY +D P+ K Y++I
Sbjct: 899 LKAHILD-GINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKI 947
Query: 108 LRS 100
+ S
Sbjct: 948 IDS 950
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 74.5 bits (175), Expect = 3e-13
Identities = 54/179 (30%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = -3
Query: 639 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 460
LP +E E+ I+GTADFF A P S L + P L+
Sbjct: 349 LPDFTESEKKFIKGTADFF-----------ALCFGPTLSFQLLDPHMKFRQLESPN-LRQ 396
Query: 459 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENIL 280
SW+ L ++N P ++ ENGW S +D + Y + + L
Sbjct: 397 LLSWIDL--------------EFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETL 442
Query: 279 DSLDA-GVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 106
++ GV + GY AWSLMD +EW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 443 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 74.5 bits (175), Expect = 3e-13
Identities = 54/179 (30%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = -3
Query: 639 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 460
LP +E E+ I+GTADFF A P S L + P L+
Sbjct: 349 LPDFTESEKKFIKGTADFF-----------ALCFGPTLSFQLLDPHMKFRQLESPN-LRQ 396
Query: 459 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENIL 280
SW+ L ++N P ++ ENGW S +D + Y + + L
Sbjct: 397 LLSWIDL--------------EFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETL 442
Query: 279 DSLDA-GVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 106
++ GV + GY AWSLMD +EW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 443 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 66.9 bits (156), Expect = 6e-11
Identities = 59/183 (32%), Positives = 85/183 (46%), Gaps = 3/183 (1%)
Frame = -3
Query: 639 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 460
LP +E+E+ LI+GT DF ++HYT LV + K P + + V WL S
Sbjct: 786 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDP----IKYNDYLEVQEMTDITWLNS 841
Query: 459 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENI 283
S + ++P + VL LK KY D Y+ NG + EDD R+ Y + +
Sbjct: 842 -PSQVAVVPWGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEA 898
Query: 282 LDS--LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEI 109
L + LD G+ L GY A+S D RFGLY +D P+ K Y++I
Sbjct: 899 LKAHILD-GINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKI 947
Query: 108 LRS 100
+ S
Sbjct: 948 IDS 950
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 74.5 bits (175), Expect = 3e-13
Identities = 54/179 (30%), Positives = 80/179 (44%), Gaps = 1/179 (0%)
Frame = -3
Query: 639 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 460
LP +E E+ I+GTADFF A P S L + P L+
Sbjct: 349 LPDFTESEKKFIKGTADFF-----------ALCFGPTLSFQLLDPHMKFRQLESPN-LRQ 396
Query: 459 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRAALENIL 280
SW+ L ++N P ++ ENGW S +D + Y + + L
Sbjct: 397 LLSWIDL--------------EFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETL 442
Query: 279 DSLDA-GVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEIL 106
++ GV + GY AWSLMD +EW GY+ R GL+ VDF + P+ SA Y++++
Sbjct: 443 KAIKLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLI 501
Score = 66.9 bits (156), Expect = 6e-11
Identities = 59/183 (32%), Positives = 85/183 (46%), Gaps = 3/183 (1%)
Frame = -3
Query: 639 LPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQS 460
LP +E+E+ LI+GT DF ++HYT LV + K P + + V WL S
Sbjct: 786 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDP----IKYNDYLEVQEMTDITWLNS 841
Query: 459 AASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDD-RITYYRAALENI 283
S + ++P + VL LK KY D Y+ NG + EDD R+ Y + +
Sbjct: 842 -PSQVAVVPWGLRKVLNWLKFKYGDLPMYIISNG--IDDGLHAEDDQLRVYYMQNYINEA 898
Query: 282 LDS--LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDFSDPARPRTPRKSAFVYKEI 109
L + LD G+ L GY A+S D RFGLY +D P+ K Y++I
Sbjct: 899 LKAHILD-GINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMKH---YRKI 947
Query: 108 LRS 100
+ S
Sbjct: 948 IDS 950
>BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein.
Length = 305
Score = 56.4 bits (130), Expect = 9e-08
Identities = 48/166 (28%), Positives = 76/166 (45%), Gaps = 2/166 (1%)
Frame = -3
Query: 657 GYPRTRLPQLSEEERVLIRGTADFFGVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRP 478
G + LP+L+E ER L++GT DF +NH+T V + E S + +
Sbjct: 58 GLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFV-----MHEQLAGSRYDSDRDIQFLQ 112
Query: 477 PEWLQSAASWLTLMPNSIYDVLTHLKNKYNDPIFYVTENGWATSPEVGLEDDDRITYYRA 298
S+ + L ++P + +L ++ Y D Y+T +G + LEDD YY
Sbjct: 113 DITRLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASG---IDDQALEDDRLRKYYLG 169
Query: 297 A-LENILDS-LDAGVRLKGYMAWSLMDNYEWMAGYTERFGLYEVDF 166
L+ +L + L VR+KGY A+ L + RFG + DF
Sbjct: 170 KYLQEVLKAYLIDKVRIKGYYAFKLAEEKS-----KPRFGFFTSDF 210
>CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein.
Length = 537
Score = 31.1 bits (67), Expect = 3.8
Identities = 18/56 (32%), Positives = 24/56 (42%)
Frame = -3
Query: 582 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIYDV 415
GVN Y L S + +Y + LF G PP+W S L P++ Y V
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPYCV 367
>U83246-1|AAC15920.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 30.7 bits (66), Expect = 5.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 582 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 421
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 30.7 bits (66), Expect = 5.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 582 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 421
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein.
Length = 386
Score = 30.7 bits (66), Expect = 5.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 582 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 421
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 288 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 341
>AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein.
Length = 481
Score = 30.7 bits (66), Expect = 5.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 582 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 421
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein.
Length = 537
Score = 30.7 bits (66), Expect = 5.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 582 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 421
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein.
Length = 517
Score = 30.7 bits (66), Expect = 5.1
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -3
Query: 582 GVNHYTGYLVSATKHIPEYSTVSLFSDINVGNYRPPEWLQSAASWLTLMPNSIY 421
GVN Y L S + +Y + LF G PP+W S L P++ Y
Sbjct: 292 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 345
>AB209169-1|BAD92406.1| 208|Homo sapiens growth differentiation
factor 1 variant protein.
Length = 208
Score = 30.3 bits (65), Expect = 6.7
Identities = 14/25 (56%), Positives = 16/25 (64%), Gaps = 1/25 (4%)
Frame = -2
Query: 154 PPSHPAQV-RVRLQGDLEEQGHRPR 83
PP HPA + R R G L +GHRPR
Sbjct: 71 PPPHPASISRPRPPGPLPLRGHRPR 95
>AF103671-1|AAD16731.1| 106|Homo sapiens immunoglobulin lambda
light chain variable region protein.
Length = 106
Score = 29.9 bits (64), Expect = 8.9
Identities = 18/71 (25%), Positives = 36/71 (50%), Gaps = 4/71 (5%)
Frame = -3
Query: 462 SAASWLTLMPNSIYDVLTHLKNKYNDPI---FYVTENGWATSPEV-GLEDDDRITYYRAA 295
++ +W L+P +L + N+ + F +++G + S + GL+ +D YY +A
Sbjct: 22 NSVNWYQLLPGKAPKLLIYNDNQRPSGVPDRFSGSKSGTSASLAISGLQSEDEAEYYCSA 81
Query: 294 LENILDSLDAG 262
+N LD + G
Sbjct: 82 WDNSLDGREFG 92
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 105,181,502
Number of Sequences: 237096
Number of extensions: 2333308
Number of successful extensions: 9505
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 9298
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 9456
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 7839245960
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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