Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV13a02f
(635 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein. 320 3e-87
AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2 prot... 320 3e-87
AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens ... 316 6e-86
AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1 prot... 314 2e-85
AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein. 314 2e-85
AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens ... 77 7e-14
U57627-1|AAB03839.2| 901|Homo sapiens ocrl1 protein. 31 4.5
M88162-1|AAA59964.2| 968|Homo sapiens Lowe oculocerebrorenal sy... 31 4.5
M76558-1|AAA58402.1| 2161|Homo sapiens calcium channel alpha-1D ... 31 4.5
BC130612-1|AAI30613.1| 893|Homo sapiens oculocerebrorenal syndr... 31 4.5
BC094726-1|AAH94726.1| 893|Homo sapiens oculocerebrorenal syndr... 31 4.5
AL662877-2|CAI41087.1| 893|Homo sapiens oculocerebrorenal syndr... 31 4.5
AL662877-1|CAI41088.1| 901|Homo sapiens oculocerebrorenal syndr... 31 4.5
AL138745-5|CAI42615.1| 893|Homo sapiens oculocerebrorenal syndr... 31 4.5
AL138745-4|CAI42616.1| 901|Homo sapiens oculocerebrorenal syndr... 31 4.5
AL022162-2|CAI95696.1| 893|Homo sapiens oculocerebrorenal syndr... 31 4.5
AL022162-1|CAI95695.1| 901|Homo sapiens oculocerebrorenal syndr... 31 4.5
>BC026179-1|AAH26179.1| 418|Homo sapiens SEC61A2 protein protein.
Length = 418
Score = 320 bits (786), Expect = 3e-87
Identities = 150/160 (93%), Positives = 159/160 (99%)
Frame = +2
Query: 155 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 334
MGIKFLEVIKPFC++LPEI KPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 335 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 514
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 515 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGL 634
M+IT+GQAIVYVMTGMYG+P+E+GAG+CLLIIIQLFVAGL
Sbjct: 121 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGL 160
>AF346603-1|AAK29084.1| 476|Homo sapiens Sec61 alpha form 2
protein.
Length = 476
Score = 320 bits (786), Expect = 3e-87
Identities = 150/160 (93%), Positives = 159/160 (99%)
Frame = +2
Query: 155 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 334
MGIKFLEVIKPFC++LPEI KPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVLPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 335 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 514
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 515 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGL 634
M+IT+GQAIVYVMTGMYG+P+E+GAG+CLLIIIQLFVAGL
Sbjct: 121 MIITIGQAIVYVMTGMYGDPAEMGAGICLLIIIQLFVAGL 160
>AK022640-1|BAB14148.1| 437|Homo sapiens protein ( Homo sapiens
cDNA FLJ12578 fis, clone NT2RM4001054, moderately
similar to Homo sapiens sec61 homolog mRNA. ).
Length = 437
Score = 316 bits (775), Expect = 6e-86
Identities = 148/160 (92%), Positives = 158/160 (98%)
Frame = +2
Query: 155 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 334
MGIKFLEVIKPFC++ PEI KPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MGIKFLEVIKPFCAVPPEIQKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 335 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 514
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 515 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGL 634
M+IT+GQAIVYV+TGMYG+P+E+GAG+CLLIIIQLFVAGL
Sbjct: 121 MIITIGQAIVYVITGMYGDPAEMGAGICLLIIIQLFVAGL 160
>AF346602-1|AAK29083.1| 476|Homo sapiens Sec61 alpha form 1
protein.
Length = 476
Score = 314 bits (770), Expect = 2e-85
Identities = 148/160 (92%), Positives = 156/160 (97%)
Frame = +2
Query: 155 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 334
M IKFLEVIKPFC ILPEI KPERKIQF+EKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 335 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 514
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 515 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGL 634
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAGL
Sbjct: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGL 160
>AF084458-1|AAD39847.1| 476|Homo sapiens sec61 homolog protein.
Length = 476
Score = 314 bits (770), Expect = 2e-85
Identities = 148/160 (92%), Positives = 156/160 (97%)
Frame = +2
Query: 155 MGIKFLEVIKPFCSILPEIAKPERKIQFREKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 334
M IKFLEVIKPFC ILPEI KPERKIQF+EKVLWTAITLFIFLVCCQIPLFGIMSSDSAD
Sbjct: 1 MAIKFLEVIKPFCVILPEIQKPERKIQFKEKVLWTAITLFIFLVCCQIPLFGIMSSDSAD 60
Query: 335 PFYWIRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 514
PFYW+RVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG
Sbjct: 61 PFYWMRVILASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALFNGAQKLFG 120
Query: 515 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGL 634
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAGL
Sbjct: 121 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGL 160
>AK074928-1|BAC11298.1| 356|Homo sapiens protein ( Homo sapiens
cDNA FLJ90447 fis, clone NT2RP3001240, highly similar to
Canis familiaris sec61 homologue mRNA. ).
Length = 356
Score = 76.6 bits (180), Expect = 7e-14
Identities = 33/40 (82%), Positives = 39/40 (97%)
Frame = +2
Query: 515 MVITVGQAIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAGL 634
M+IT+GQ+IVYVMTGMYG+PSE+GAG+CLLI IQLFVAGL
Sbjct: 1 MIITIGQSIVYVMTGMYGDPSEMGAGICLLITIQLFVAGL 40
>U57627-1|AAB03839.2| 901|Homo sapiens ocrl1 protein.
Length = 901
Score = 30.7 bits (66), Expect = 4.5
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +1
Query: 232 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 372
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 775 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 827
>M88162-1|AAA59964.2| 968|Homo sapiens Lowe oculocerebrorenal
syndrome protein protein.
Length = 968
Score = 30.7 bits (66), Expect = 4.5
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +1
Query: 232 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 372
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 842 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 894
>M76558-1|AAA58402.1| 2161|Homo sapiens calcium channel alpha-1D
subunit protein.
Length = 2161
Score = 30.7 bits (66), Expect = 4.5
Identities = 32/96 (33%), Positives = 45/96 (46%), Gaps = 5/96 (5%)
Frame = +2
Query: 359 LASNRGTLMELGISPIVTSGLIMQLLAGAKIIEVGDTPKDRALF-NGAQKLFGMV-ITVG 532
+ S+ L+ L + I+ S L MQL G +T R+ F N Q L + I G
Sbjct: 647 MKSSASLLLLLFLFIIIFSLLGMQLFGGK--FNFDETQTKRSTFDNFPQALLTVFQILTG 704
Query: 533 Q---AIVYVMTGMYGEPSEIGAGVCLLIIIQLFVAG 631
+ A++Y YG PS G VC+ II LF+ G
Sbjct: 705 EDWNAVMYDGIMAYGGPSSSGMIVCIYFII-LFICG 739
>BC130612-1|AAI30613.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 30.7 bits (66), Expect = 4.5
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +1
Query: 232 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 372
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 767 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 819
>BC094726-1|AAH94726.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 30.7 bits (66), Expect = 4.5
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +1
Query: 232 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 372
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 767 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 819
>AL662877-2|CAI41087.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 30.7 bits (66), Expect = 4.5
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +1
Query: 232 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 372
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 767 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 819
>AL662877-1|CAI41088.1| 901|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 901
Score = 30.7 bits (66), Expect = 4.5
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +1
Query: 232 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 372
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 775 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 827
>AL138745-5|CAI42615.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 30.7 bits (66), Expect = 4.5
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +1
Query: 232 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 372
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 767 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 819
>AL138745-4|CAI42616.1| 901|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 901
Score = 30.7 bits (66), Expect = 4.5
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +1
Query: 232 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 372
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 775 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 827
>AL022162-2|CAI95696.1| 893|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 893
Score = 30.7 bits (66), Expect = 4.5
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +1
Query: 232 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 372
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 767 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 819
>AL022162-1|CAI95695.1| 901|Homo sapiens oculocerebrorenal syndrome
of Lowe protein.
Length = 901
Score = 30.7 bits (66), Expect = 4.5
Identities = 20/54 (37%), Positives = 28/54 (51%), Gaps = 7/54 (12%)
Frame = +1
Query: 232 SIPRESIMDSNH-----IIYFLSMLPDSLIWYNVIRQCRSLLLDP--CNSCIKQ 372
SIP E+I SNH ++ FL LP+ +I Y + ++C DP C I Q
Sbjct: 775 SIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICRQVISQ 827
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 91,591,342
Number of Sequences: 237096
Number of extensions: 1847462
Number of successful extensions: 3441
Number of sequences better than 10.0: 17
Number of HSP's better than 10.0 without gapping: 3353
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3441
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 6972732040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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