Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV12g07r
(705 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
EF426482-1|ABR08387.1| 399|Homo sapiens lipase K protein. 90 8e-18
AL358532-3|CAH71058.2| 399|Homo sapiens lipase, family member K... 90 8e-18
Z31690-1|CAA83495.1| 399|Homo sapiens lysosomal acid lipase pro... 87 8e-17
X76488-1|CAA54026.1| 399|Homo sapiens sterol esterase protein. 87 8e-17
U08464-1|AAB60328.1| 399|Homo sapiens lysosomal acid lipase pro... 87 8e-17
U04285-1|AAB60327.1| 399|Homo sapiens lysosomal acid lipase/cho... 87 8e-17
M74775-1|AAA59519.1| 399|Homo sapiens lysosomal acid lipase/cho... 87 8e-17
BC012287-1|AAH12287.1| 399|Homo sapiens lipase A, lysosomal aci... 87 8e-17
AL513533-2|CAI13516.1| 399|Homo sapiens lipase A, lysosomal aci... 87 8e-17
AL513533-1|CAI13515.1| 343|Homo sapiens lipase A, lysosomal aci... 87 8e-17
AL353751-3|CAI12236.1| 399|Homo sapiens lipase A, lysosomal aci... 87 8e-17
AL353751-1|CAI12234.1| 343|Homo sapiens lipase A, lysosomal aci... 87 8e-17
AL353146-2|CAI12380.1| 343|Homo sapiens lipase A, lysosomal aci... 87 8e-17
AK222760-1|BAD96480.1| 399|Homo sapiens lipase A precursor vari... 87 8e-17
AK125193-1|BAC86078.1| 401|Homo sapiens . protein. 87 8e-17
X05997-2|CAA29414.1| 392|Homo sapiens gastric lipase precursor ... 86 1e-16
X05997-1|CAA29413.1| 398|Homo sapiens gastric lipase precursor ... 86 1e-16
BC113711-1|AAI13712.1| 398|Homo sapiens lipase, gastric protein. 86 1e-16
BC112272-1|AAI12273.1| 398|Homo sapiens lipase, gastric protein. 86 1e-16
AY631869-1|AAT38115.1| 398|Homo sapiens lipase, gastric protein. 86 1e-16
AL358532-2|CAH71056.1| 365|Homo sapiens lipase, gastric protein. 86 1e-16
AL358532-1|CAH71057.1| 398|Homo sapiens lipase, gastric protein. 86 1e-16
AK223468-1|BAD97188.1| 398|Homo sapiens lipase, gastric variant... 86 1e-16
AL139406-3|CAH73713.1| 366|Homo sapiens lipase, family member J... 79 2e-14
EF426484-1|ABR08389.1| 423|Homo sapiens lipase M protein. 78 3e-14
BC031219-1|AAH31219.1| 366|Homo sapiens lipase, family member J... 78 3e-14
AL358532-7|CAO77925.1| 423|Homo sapiens lipase, family member M... 78 3e-14
AL353113-2|CAH72238.2| 423|Homo sapiens lipase, family member M... 78 3e-14
EF426483-1|ABR08388.1| 398|Homo sapiens lipase N protein. 77 6e-14
AL358532-5|CAH71060.2| 398|Homo sapiens lipase, family member N... 77 6e-14
AL513533-3|CAI13517.1| 290|Homo sapiens lipase A, lysosomal aci... 40 0.009
AL353751-4|CAI12237.1| 290|Homo sapiens lipase A, lysosomal aci... 40 0.009
>EF426482-1|ABR08387.1| 399|Homo sapiens lipase K protein.
Length = 399
Score = 89.8 bits (213), Expect = 8e-18
Identities = 56/217 (25%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFT 517
S PE KI A APV +++ + + KL ++ L +++F F
Sbjct: 183 STNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFG----DKMFHPHTLFD 238
Query: 516 NLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLI 337
+ F+ +C+N LF +G N + L V L H PAG +V+ + H+ Q +
Sbjct: 239 QFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAV 298
Query: 336 NKNFFRRYDHGRL-TNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAEL 160
N + +D G N + TPP Y+++ + P + +DI AD +DV L ++
Sbjct: 299 NSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQI 358
Query: 159 GRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQIL 49
+ +PH ++H+DF G A +Y I ++
Sbjct: 359 ANLIYYKLIPH--YNHVDFYLGEDAPQEIYQDLIILM 393
>AL358532-3|CAH71058.2| 399|Homo sapiens lipase, family member K
protein.
Length = 399
Score = 89.8 bits (213), Expect = 8e-18
Identities = 56/217 (25%), Positives = 97/217 (44%), Gaps = 1/217 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFT 517
S PE KI A APV +++ + + KL ++ L +++F F
Sbjct: 183 STNPELAKKIKIFFALAPVVTVKYTQSPMKKLTTLSRRVVKVLFG----DKMFHPHTLFD 238
Query: 516 NLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLI 337
+ F+ +C+N LF +G N + L V L H PAG +V+ + H+ Q +
Sbjct: 239 QFIATKVCNRKLFRRICSNFLFTLSGFDPQNLNMSRLDVYLSHNPAGTSVQNMLHWAQAV 298
Query: 336 NKNFFRRYDHGRL-TNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAEL 160
N + +D G N + TPP Y+++ + P + +DI AD +DV L ++
Sbjct: 299 NSGQLQAFDWGNSDQNMMHFHQLTPPLYNITKMEVPTAIWNGGQDIVADPKDVENLLPQI 358
Query: 159 GRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQIL 49
+ +PH ++H+DF G A +Y I ++
Sbjct: 359 ANLIYYKLIPH--YNHVDFYLGEDAPQEIYQDLIILM 393
>Z31690-1|CAA83495.1| 399|Homo sapiens lysosomal acid lipase
protein.
Length = 399
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 303
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 304 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 363
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 364 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 396
>X76488-1|CAA54026.1| 399|Homo sapiens sterol esterase protein.
Length = 399
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 303
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 304 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 363
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 364 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 396
>U08464-1|AAB60328.1| 399|Homo sapiens lysosomal acid lipase
protein.
Length = 399
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 303
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 304 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 363
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 364 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 396
>U04285-1|AAB60327.1| 399|Homo sapiens lysosomal acid
lipase/cholesteryl ester hydrolase protein.
Length = 399
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 303
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 304 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 363
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 364 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 396
>M74775-1|AAA59519.1| 399|Homo sapiens lysosomal acid
lipase/cholesteryl esterase protein.
Length = 399
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 303
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 304 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 363
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 364 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 396
>BC012287-1|AAH12287.1| 399|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 399
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 303
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 304 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 363
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 364 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 396
>AL513533-2|CAI13516.1| 399|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 399
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 303
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 304 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 363
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 364 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 396
>AL513533-1|CAI13515.1| 343|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 343
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 132 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 188
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 189 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 247
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 248 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 307
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 308 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 340
>AL353751-3|CAI12236.1| 399|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 399
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 303
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 304 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 363
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 364 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 396
>AL353751-1|CAI12234.1| 343|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 343
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 132 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 188
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 189 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 247
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 248 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 307
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 308 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 340
>AL353146-2|CAI12380.1| 343|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 343
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 132 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 188
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 189 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 247
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 248 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 307
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 308 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 340
>AK222760-1|BAD96480.1| 399|Homo sapiens lipase A precursor variant
protein.
Length = 399
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 303
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 304 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 363
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 364 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 396
>AK125193-1|BAC86078.1| 401|Homo sapiens . protein.
Length = 401
Score = 86.6 bits (205), Expect = 8e-17
Identities = 62/215 (28%), Positives = 97/215 (45%), Gaps = 1/215 (0%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 190 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 246
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKN 328
C + +C N+ F G +E N + + V H+PAG +V+ + H+ Q +
Sbjct: 247 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSVQNMLHWSQAVKFQ 305
Query: 327 FFRRYDHG-RLTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRS 151
F+ +D G N+ Y PP Y++ + P + D ADV DV L ++
Sbjct: 306 KFQAFDWGSSAKNYFHYNQSYPPTYNVKDMLVPTAVWSGGHDWLADVYDVNILLTQITNL 365
Query: 150 VGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
V +P + HLDF+WG A LY++ I ++R
Sbjct: 366 VFHESIPE--WEHLDFIWGLDAPWRLYNKIINLMR 398
>X05997-2|CAA29414.1| 392|Homo sapiens gastric lipase precursor
protein.
Length = 392
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/218 (26%), Positives = 99/218 (45%), Gaps = 2/218 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL-IAPHANSIEALTSLIGINELFGRSDFF 520
S P +I A APVA +++ + + KL P ++L I +++F +FF
Sbjct: 177 STNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVP-----QSLFKFIFGDKIFYPHNFF 231
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
+C+N LF G N + L V L H PAG +V+ + H+ Q
Sbjct: 232 DQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQA 291
Query: 339 INKNFFRRYDHGR-LTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+ F+ YD G + N Y PP Y+++ + P+ + +D+ AD +DV L +
Sbjct: 292 VKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPK 351
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQIL 49
L + +P ++HLDF+W A +Y+ + ++
Sbjct: 352 LPNLIYHKEIPF--YNHLDFIWAMDAPQEVYNDIVSMI 387
>X05997-1|CAA29413.1| 398|Homo sapiens gastric lipase precursor
protein.
Length = 398
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/218 (26%), Positives = 99/218 (45%), Gaps = 2/218 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL-IAPHANSIEALTSLIGINELFGRSDFF 520
S P +I A APVA +++ + + KL P ++L I +++F +FF
Sbjct: 183 STNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVP-----QSLFKFIFGDKIFYPHNFF 237
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
+C+N LF G N + L V L H PAG +V+ + H+ Q
Sbjct: 238 DQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQA 297
Query: 339 INKNFFRRYDHGR-LTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+ F+ YD G + N Y PP Y+++ + P+ + +D+ AD +DV L +
Sbjct: 298 VKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPK 357
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQIL 49
L + +P ++HLDF+W A +Y+ + ++
Sbjct: 358 LPNLIYHKEIPF--YNHLDFIWAMDAPQEVYNDIVSMI 393
>BC113711-1|AAI13712.1| 398|Homo sapiens lipase, gastric protein.
Length = 398
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/218 (26%), Positives = 99/218 (45%), Gaps = 2/218 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL-IAPHANSIEALTSLIGINELFGRSDFF 520
S P +I A APVA +++ + + KL P ++L I +++F +FF
Sbjct: 183 STNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVP-----QSLFKFIFGDKIFYPHNFF 237
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
+C+N LF G N + L V L H PAG +V+ + H+ Q
Sbjct: 238 DQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQA 297
Query: 339 INKNFFRRYDHGR-LTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+ F+ YD G + N Y PP Y+++ + P+ + +D+ AD +DV L +
Sbjct: 298 VKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPK 357
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQIL 49
L + +P ++HLDF+W A +Y+ + ++
Sbjct: 358 LPNLIYHKEIPF--YNHLDFIWAMDAPQEVYNDIVSMI 393
>BC112272-1|AAI12273.1| 398|Homo sapiens lipase, gastric protein.
Length = 398
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/218 (26%), Positives = 99/218 (45%), Gaps = 2/218 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL-IAPHANSIEALTSLIGINELFGRSDFF 520
S P +I A APVA +++ + + KL P ++L I +++F +FF
Sbjct: 183 STNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVP-----QSLFKFIFGDKIFYPHNFF 237
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
+C+N LF G N + L V L H PAG +V+ + H+ Q
Sbjct: 238 DQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQA 297
Query: 339 INKNFFRRYDHGR-LTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+ F+ YD G + N Y PP Y+++ + P+ + +D+ AD +DV L +
Sbjct: 298 VKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPK 357
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQIL 49
L + +P ++HLDF+W A +Y+ + ++
Sbjct: 358 LPNLIYHKEIPF--YNHLDFIWAMDAPQEVYNDIVSMI 393
>AY631869-1|AAT38115.1| 398|Homo sapiens lipase, gastric protein.
Length = 398
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/218 (26%), Positives = 99/218 (45%), Gaps = 2/218 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL-IAPHANSIEALTSLIGINELFGRSDFF 520
S P +I A APVA +++ + + KL P ++L I +++F +FF
Sbjct: 183 STNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVP-----QSLFKFIFGDKIFYPHNFF 237
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
+C+N LF G N + L V L H PAG +V+ + H+ Q
Sbjct: 238 DQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQA 297
Query: 339 INKNFFRRYDHGR-LTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+ F+ YD G + N Y PP Y+++ + P+ + +D+ AD +DV L +
Sbjct: 298 VKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPK 357
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQIL 49
L + +P ++HLDF+W A +Y+ + ++
Sbjct: 358 LPNLIYHKEIPF--YNHLDFIWAMDAPQEVYNDIVSMI 393
>AL358532-2|CAH71056.1| 365|Homo sapiens lipase, gastric protein.
Length = 365
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/218 (26%), Positives = 99/218 (45%), Gaps = 2/218 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL-IAPHANSIEALTSLIGINELFGRSDFF 520
S P +I A APVA +++ + + KL P ++L I +++F +FF
Sbjct: 150 STNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVP-----QSLFKFIFGDKIFYPHNFF 204
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
+C+N LF G N + L V L H PAG +V+ + H+ Q
Sbjct: 205 DQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQA 264
Query: 339 INKNFFRRYDHGR-LTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+ F+ YD G + N Y PP Y+++ + P+ + +D+ AD +DV L +
Sbjct: 265 VKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPK 324
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQIL 49
L + +P ++HLDF+W A +Y+ + ++
Sbjct: 325 LPNLIYHKEIPF--YNHLDFIWAMDAPQEVYNDIVSMI 360
>AL358532-1|CAH71057.1| 398|Homo sapiens lipase, gastric protein.
Length = 398
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/218 (26%), Positives = 99/218 (45%), Gaps = 2/218 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL-IAPHANSIEALTSLIGINELFGRSDFF 520
S P +I A APVA +++ + + KL P ++L I +++F +FF
Sbjct: 183 STNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVP-----QSLFKFIFGDKIFYPHNFF 237
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
+C+N LF G N + L V L H PAG +V+ + H+ Q
Sbjct: 238 DQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQNMFHWTQA 297
Query: 339 INKNFFRRYDHGR-LTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+ F+ YD G + N Y PP Y+++ + P+ + +D+ AD +DV L +
Sbjct: 298 VKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPK 357
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQIL 49
L + +P ++HLDF+W A +Y+ + ++
Sbjct: 358 LPNLIYHKEIPF--YNHLDFIWAMDAPQEVYNDIVSMI 393
>AK223468-1|BAD97188.1| 398|Homo sapiens lipase, gastric variant
protein.
Length = 398
Score = 85.8 bits (203), Expect = 1e-16
Identities = 57/218 (26%), Positives = 99/218 (45%), Gaps = 2/218 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLKL-IAPHANSIEALTSLIGINELFGRSDFF 520
S P +I A APVA +++ + + KL P ++L I +++F +FF
Sbjct: 183 STNPSLAKRIKTFYALAPVATVKYTKSLINKLRFVP-----QSLFKFIFGDKIFYPHNFF 237
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
+C+N LF G N + L V L H PAG +V+ + H+ Q
Sbjct: 238 DQFLATEVCSREMLNLLCSNALFIICGFDSKNFNTSRLDVYLSHNPAGTSVQSMFHWTQA 297
Query: 339 INKNFFRRYDHGR-LTNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+ F+ YD G + N Y PP Y+++ + P+ + +D+ AD +DV L +
Sbjct: 298 VKSGKFQAYDWGSPVQNRMHYDQSQPPYYNVTAMNVPIAVWNGGKDLLADPQDVGLLLPK 357
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQIL 49
L + +P ++HLDF+W A +Y+ + ++
Sbjct: 358 LPNLIYHKEIPF--YNHLDFIWAMDAPQEVYNDIVSMI 393
>AL139406-3|CAH73713.1| 366|Homo sapiens lipase, family member J
protein.
Length = 366
Score = 78.6 bits (185), Expect = 2e-14
Identities = 51/204 (25%), Positives = 93/204 (45%), Gaps = 1/204 (0%)
Frame = -1
Query: 654 AYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLGMRFCADGTFFQ 475
A APV ++ + L+++ + + A + G + ++ F +G + C F
Sbjct: 166 ALAPVFSTKYLKSPLIRMTYKWKSIVMAFS---GNKDFLPKTSFKKFIGSKLCPL-QIFD 221
Query: 474 AMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKNFFRRYDHGRL- 298
+C N+LF G N + L V H PAG +V+ + H+ QL+N + YD G
Sbjct: 222 KICLNILFMMFGYDPKNLNMSRLDVYFSHNPAGTSVQNMLHWSQLLNSTHLKAYDWGSPD 281
Query: 297 TNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRSVGMFRVPHATF 118
N Y T P Y+++ + + D+ AD DV LH+E+ + + + +
Sbjct: 282 LNLVHYNQTTSPLYNMTNMNVATAIWNGKSDLLADPEDVNILHSEITNHIYYKTISY--Y 339
Query: 117 SHLDFMWGSGAKDLLYDRTIQILR 46
+H+D ++G D +Y I I++
Sbjct: 340 NHIDSLFGLDVYDQVYHEIIDIIQ 363
>EF426484-1|ABR08389.1| 423|Homo sapiens lipase M protein.
Length = 423
Score = 78.2 bits (184), Expect = 3e-14
Identities = 57/219 (26%), Positives = 98/219 (44%), Gaps = 2/219 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLK-LIAPHANSIEALTSLIGINELFGRSDFF 520
S PE KI A AP+A ++ + K L+ P + L G E ++ F
Sbjct: 197 STMPELAQKIKMYFALAPIATVKHAKSPGTKFLLLPDM----MIKGLFGKKEFLYQTRFL 252
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
L + C +C+N++ G + + N + V HT AG +V+ I H+ Q
Sbjct: 253 RQLVIYLCGQ-VILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLAGTSVQNILHWSQA 311
Query: 339 INKNFFRRYDHGRLT-NWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+N R +D G T N TP RY + +T P + +D ++ DV+ L +E
Sbjct: 312 VNSGELRAFDWGSETKNLEKCNQPTPVRYRVRDMTVPTAMWTGGQDWLSNPEDVKMLLSE 371
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
+ + +P ++H+DF+WG A +Y+ I +++
Sbjct: 372 VTNLIYHKNIPE--WAHVDFIWGLDAPHRMYNEIIHLMQ 408
>BC031219-1|AAH31219.1| 366|Homo sapiens lipase, family member J
protein.
Length = 366
Score = 78.2 bits (184), Expect = 3e-14
Identities = 51/204 (25%), Positives = 93/204 (45%), Gaps = 1/204 (0%)
Frame = -1
Query: 654 AYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLGMRFCADGTFFQ 475
A APV ++ + L+++ + + A + G + ++ F +G + C F
Sbjct: 166 ALAPVFSTKYLKSPLIRMTYKWKSIVMAFS---GNKDFLPKTSFKKFVGSKLCPL-QIFD 221
Query: 474 AMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQLINKNFFRRYDHGRL- 298
+C N+LF G N + L V H PAG +V+ + H+ QL+N + YD G
Sbjct: 222 KICLNILFMMFGYDPKNLNMSRLDVYFSHNPAGTSVQNMLHWSQLLNSTHLKAYDWGSPD 281
Query: 297 TNWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAELGRSVGMFRVPHATF 118
N Y T P Y+++ + + D+ AD DV LH+E+ + + + +
Sbjct: 282 LNLVHYNQTTSPLYNMTNMNVATAIWNGKSDLLADPEDVNILHSEITNHIYYKTISY--Y 339
Query: 117 SHLDFMWGSGAKDLLYDRTIQILR 46
+H+D ++G D +Y I I++
Sbjct: 340 NHIDSLFGLDVYDQVYHEIIDIIQ 363
>AL358532-7|CAO77925.1| 423|Homo sapiens lipase, family member M
protein.
Length = 423
Score = 78.2 bits (184), Expect = 3e-14
Identities = 57/219 (26%), Positives = 98/219 (44%), Gaps = 2/219 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLK-LIAPHANSIEALTSLIGINELFGRSDFF 520
S PE KI A AP+A ++ + K L+ P + L G E ++ F
Sbjct: 197 STMPELAQKIKMYFALAPIATVKHAKSPGTKFLLLPDM----MIKGLFGKKEFLYQTRFL 252
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
L + C +C+N++ G + + N + V HT AG +V+ I H+ Q
Sbjct: 253 RQLVIYLCGQ-VILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLAGTSVQNILHWSQA 311
Query: 339 INKNFFRRYDHGRLT-NWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+N R +D G T N TP RY + +T P + +D ++ DV+ L +E
Sbjct: 312 VNSGELRAFDWGSETKNLEKCNQPTPVRYRVRDMTVPTAMWTGGQDWLSNPEDVKMLLSE 371
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
+ + +P ++H+DF+WG A +Y+ I +++
Sbjct: 372 VTNLIYHKNIPE--WAHVDFIWGLDAPHRMYNEIIHLMQ 408
>AL353113-2|CAH72238.2| 423|Homo sapiens lipase, family member M
protein.
Length = 423
Score = 78.2 bits (184), Expect = 3e-14
Identities = 57/219 (26%), Positives = 98/219 (44%), Gaps = 2/219 (0%)
Frame = -1
Query: 696 SLRPEYNSKIIAMQAYAPVAYLEFNANRLLK-LIAPHANSIEALTSLIGINELFGRSDFF 520
S PE KI A AP+A ++ + K L+ P + L G E ++ F
Sbjct: 197 STMPELAQKIKMYFALAPIATVKHAKSPGTKFLLLPDM----MIKGLFGKKEFLYQTRFL 252
Query: 519 TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAVRQIAHYGQL 340
L + C +C+N++ G + + N + V HT AG +V+ I H+ Q
Sbjct: 253 RQLVIYLCGQ-VILDQICSNIMLLLGGFNTNNMNMSRASVYAAHTLAGTSVQNILHWSQA 311
Query: 339 INKNFFRRYDHGRLT-NWRVYRSFTPPRYDLSLITAPVFLHYVDEDIFADVRDVRKLHAE 163
+N R +D G T N TP RY + +T P + +D ++ DV+ L +E
Sbjct: 312 VNSGELRAFDWGSETKNLEKCNQPTPVRYRVRDMTVPTAMWTGGQDWLSNPEDVKMLLSE 371
Query: 162 LGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILR 46
+ + +P ++H+DF+WG A +Y+ I +++
Sbjct: 372 VTNLIYHKNIPE--WAHVDFIWGLDAPHRMYNEIIHLMQ 408
>EF426483-1|ABR08388.1| 398|Homo sapiens lipase N protein.
Length = 398
Score = 77.0 bits (181), Expect = 6e-14
Identities = 45/176 (25%), Positives = 82/176 (46%), Gaps = 6/176 (3%)
Frame = -1
Query: 552 INELFGRSDFF-----TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGH 388
I +FG FF T + + +C+ + +AG ++ N + + V + H
Sbjct: 223 IKAVFGTKGFFLEDKKTKIASTKICNNKILWLICSEFMSLWAGSNKKNMNQSRMDVYMSH 282
Query: 387 TPAGIAVRQIAHYGQLINKNFFRRYDHGR-LTNWRVYRSFTPPRYDLSLITAPVFLHYVD 211
P G +V I H QL + + FR YD G N + Y PP YDL+ + P +
Sbjct: 283 APTGSSVHNILHIKQLYHSDEFRAYDWGNDADNMKHYNQSHPPIYDLTAMKVPTAIWAGG 342
Query: 210 EDIFADVRDVRKLHAELGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILRS 43
D+ +DV ++ ++ +S+ F++ ++H DF+WG A +Y I ++++
Sbjct: 343 HDVLVTPQDVARILPQI-KSLHYFKL-LPDWNHFDFVWGLDAPQRMYSEIIALMKA 396
>AL358532-5|CAH71060.2| 398|Homo sapiens lipase, family member N
protein.
Length = 398
Score = 77.0 bits (181), Expect = 6e-14
Identities = 45/176 (25%), Positives = 82/176 (46%), Gaps = 6/176 (3%)
Frame = -1
Query: 552 INELFGRSDFF-----TNLGMRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGH 388
I +FG FF T + + +C+ + +AG ++ N + + V + H
Sbjct: 223 IKAVFGTKGFFLEDKKTKIASTKICNNKILWLICSEFMSLWAGSNKKNMNQSRMDVYMSH 282
Query: 387 TPAGIAVRQIAHYGQLINKNFFRRYDHGR-LTNWRVYRSFTPPRYDLSLITAPVFLHYVD 211
P G +V I H QL + + FR YD G N + Y PP YDL+ + P +
Sbjct: 283 APTGSSVHNILHIKQLYHSDEFRAYDWGNDADNMKHYNQSHPPIYDLTAMKVPTAIWAGG 342
Query: 210 EDIFADVRDVRKLHAELGRSVGMFRVPHATFSHLDFMWGSGAKDLLYDRTIQILRS 43
D+ +DV ++ ++ +S+ F++ ++H DF+WG A +Y I ++++
Sbjct: 343 HDVLVTPQDVARILPQI-KSLHYFKL-LPDWNHFDFVWGLDAPQRMYSEIIALMKA 396
>AL513533-3|CAI13517.1| 290|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 290
Score = 39.9 bits (89), Expect = 0.009
Identities = 31/107 (28%), Positives = 46/107 (42%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAV 367
C + +C N+ F G +E N + + V H+PAG +V
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSV 290
>AL353751-4|CAI12237.1| 290|Homo sapiens lipase A, lysosomal acid,
cholesterol esterase (Wolman disease) protein.
Length = 290
Score = 39.9 bits (89), Expect = 0.009
Identities = 31/107 (28%), Positives = 46/107 (42%)
Frame = -1
Query: 687 PEYNSKIIAMQAYAPVAYLEFNANRLLKLIAPHANSIEALTSLIGINELFGRSDFFTNLG 508
PE +I A PVA + F + + KL + I+ L G E +S F LG
Sbjct: 188 PELAKRIKMFFALGPVASVAFCTSPMAKLGRLPDHLIK---DLFGDKEFLPQSAFLKWLG 244
Query: 507 MRFCADGTFFQAMCTNMLFAFAGRSEDMHNATMLPVKLGHTPAGIAV 367
C + +C N+ F G +E N + + V H+PAG +V
Sbjct: 245 THVCTH-VILKELCGNLCFLLCGFNERNLNMSRVDVYTTHSPAGTSV 290
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 99,379,687
Number of Sequences: 237096
Number of extensions: 2107778
Number of successful extensions: 3788
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 3613
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3737
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8175213644
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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