Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV12f22r
(700 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 171 2e-42
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 171 2e-42
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 171 2e-42
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 159 7e-39
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 159 9e-39
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 157 5e-38
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 157 5e-38
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 157 5e-38
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 157 5e-38
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 157 5e-38
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 153 8e-37
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 77 8e-14
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 77 8e-14
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 77 8e-14
BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein. 73 1e-12
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 72 2e-12
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 72 2e-12
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 72 2e-12
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 72 2e-12
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 72 2e-12
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 64 5e-10
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 64 5e-10
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 64 5e-10
BC036025-1|AAH36025.1| 1070|Homo sapiens protocadherin 8 protein. 30 6.9
AY013873-1|AAK21986.1| 973|Homo sapiens protocadherin ARCADLIN ... 30 6.9
AL139085-5|CAI14111.1| 973|Homo sapiens protocadherin 8 protein. 30 6.9
AL139085-4|CAI14110.1| 1070|Homo sapiens protocadherin 8 protein. 30 6.9
AF061573-1|AAC70009.2| 1070|Homo sapiens protocadherin protein. 30 6.9
BC106021-1|AAI06022.1| 469|Homo sapiens SBNO2 protein protein. 30 9.1
AK074102-1|BAB84928.1| 1269|Homo sapiens FLJ00173 protein protein. 30 9.1
AC005390-2|AAC28919.1| 1384|Homo sapiens R31180_1 protein. 30 9.1
AB023180-1|BAA76807.2| 1391|Homo sapiens KIAA0963 protein protein. 30 9.1
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 171 bits (417), Expect = 2e-42
Identities = 87/215 (40%), Positives = 122/215 (56%), Gaps = 2/215 (0%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G + PIF + GDY E++K R+ +S G +SR PE + E + I GT DFFG NHY+
Sbjct: 1626 GWFAHPIFKN-GDYSEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYT 1684
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
T L Y I S++ D GV W +K TP+GF ++L + YN
Sbjct: 1685 TVLAYNLNYATA---ISSFDADRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYN 1741
Query: 335 NVPIIITENGFATL--TGFEDNDRITHLRLYLNALLDAIKDGSDIRLYTPWSLMDNFEWM 162
+ PI +TENG + T D RI +LR Y+N L A++D D+R YT WS MDNFEW
Sbjct: 1742 DPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWA 1801
Query: 161 SGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
+G+++RFGL+ V+Y P L R P+ SA + +V+
Sbjct: 1802 TGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 159 bits (386), Expect = 9e-39
Identities = 89/229 (38%), Positives = 127/229 (55%), Gaps = 3/229 (1%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLN-HY 519
G + PIF + GDYP+ +K +V +S Q SR P + EE ++IR T+D F LN +Y
Sbjct: 1152 GWFAHPIFRN-GDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYY 1210
Query: 518 STFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFY 339
S + ++ + PSY DD + + W + NR PWG +LL I Y
Sbjct: 1211 SRIVQHKTPRL----NPPSYEDDQEMAEEEDPSWPSTAMNRA--APWGTRRLLNWIKEEY 1264
Query: 338 NNVPIIITENGFA-TLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNFEW 165
++PI ITENG T ED DRI + + Y+N L A + DG D+R Y WSLMDNFEW
Sbjct: 1265 GDIPIYITENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEW 1324
Query: 164 MSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLDFDYKPESL 18
++GYT +FGLY VD+++ RT R SA + E++ + + + E L
Sbjct: 1325 LNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGMPLAREDEFL 1373
Score = 131 bits (317), Expect = 2e-30
Identities = 75/219 (34%), Positives = 119/219 (54%), Gaps = 6/219 (2%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G + P+F D GDYP ++ ++ + + ++ PE + E Q ++G++DF GL+HY+
Sbjct: 629 GWFAHPVFVD-GDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYT 687
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
+ L IPSY+ G + W S + ++ PWG +LL+ +S Y
Sbjct: 688 SRLISNAPQNTC---IPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLEYT 744
Query: 335 N--VPIIITENGFATLTG---FEDNDRITHLRLYLNALLDAIKDGS-DIRLYTPWSLMDN 174
VPI + NG F+D+ R+ + Y+N +L AIK+ S D+R Y SL+D
Sbjct: 745 RGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDG 804
Query: 173 FEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
FE SGY+QRFGL+ V++ +RTPRKSA+ F I++
Sbjct: 805 FEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIE 843
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 171 bits (416), Expect = 2e-42
Identities = 87/215 (40%), Positives = 122/215 (56%), Gaps = 2/215 (0%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G + PIF + GDY E++K R+ +S G +SR PE + E + I GT DFFG NHY+
Sbjct: 1626 GWFAHPIFKN-GDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYT 1684
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
T L Y I S++ D GV W +K TP+GF ++L + YN
Sbjct: 1685 TVLAYNLNYATA---ISSFDADRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYN 1741
Query: 335 NVPIIITENGFATL--TGFEDNDRITHLRLYLNALLDAIKDGSDIRLYTPWSLMDNFEWM 162
+ PI +TENG + T D RI +LR Y+N L A++D D+R YT WS MDNFEW
Sbjct: 1742 DPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWA 1801
Query: 161 SGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
+G+++RFGL+ V+Y P L R P+ SA + +V+
Sbjct: 1802 TGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 159 bits (386), Expect = 9e-39
Identities = 89/229 (38%), Positives = 127/229 (55%), Gaps = 3/229 (1%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLN-HY 519
G + PIF + GDYP+ +K +V +S Q SR P + EE ++IR T+D F LN +Y
Sbjct: 1152 GWFAHPIFRN-GDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYY 1210
Query: 518 STFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFY 339
S + ++ + PSY DD + + W + NR PWG +LL I Y
Sbjct: 1211 SRIVQHKTPRL----NPPSYEDDQEMAEEEDPSWPSTAMNRA--APWGTRRLLNWIKEEY 1264
Query: 338 NNVPIIITENGFA-TLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNFEW 165
++PI ITENG T ED DRI + + Y+N L A + DG D+R Y WSLMDNFEW
Sbjct: 1265 GDIPIYITENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEW 1324
Query: 164 MSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLDFDYKPESL 18
++GYT +FGLY VD+++ RT R SA + E++ + + + E L
Sbjct: 1325 LNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGMPLAREDEFL 1373
Score = 131 bits (317), Expect = 2e-30
Identities = 75/219 (34%), Positives = 119/219 (54%), Gaps = 6/219 (2%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G + P+F D GDYP ++ ++ + + ++ PE + E Q ++G++DF GL+HY+
Sbjct: 629 GWFAHPVFVD-GDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYT 687
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
+ L IPSY+ G + W S + ++ PWG +LL+ +S Y
Sbjct: 688 SRLISNAPQNTC---IPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLEYT 744
Query: 335 N--VPIIITENGFATLTG---FEDNDRITHLRLYLNALLDAIKDGS-DIRLYTPWSLMDN 174
VPI + NG F+D+ R+ + Y+N +L AIK+ S D+R Y SL+D
Sbjct: 745 RGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDG 804
Query: 173 FEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
FE SGY+QRFGL+ V++ +RTPRKSA+ F I++
Sbjct: 805 FEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIE 843
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 171 bits (416), Expect = 2e-42
Identities = 87/215 (40%), Positives = 122/215 (56%), Gaps = 2/215 (0%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G + PIF + GDY E++K R+ +S G +SR PE + E + I GT DFFG NHY+
Sbjct: 1626 GWFAHPIFKN-GDYNEVMKTRIRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYT 1684
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
T L Y I S++ D GV W +K TP+GF ++L + YN
Sbjct: 1685 TVLAYNLNYATA---ISSFDADRGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYN 1741
Query: 335 NVPIIITENGFATL--TGFEDNDRITHLRLYLNALLDAIKDGSDIRLYTPWSLMDNFEWM 162
+ PI +TENG + T D RI +LR Y+N L A++D D+R YT WS MDNFEW
Sbjct: 1742 DPPIYVTENGVSQREETDLNDTARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWA 1801
Query: 161 SGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
+G+++RFGL+ V+Y P L R P+ SA + +V+
Sbjct: 1802 TGFSERFGLHFVNYSDPSLPRIPKASAKFYASVVR 1836
Score = 159 bits (386), Expect = 9e-39
Identities = 89/229 (38%), Positives = 127/229 (55%), Gaps = 3/229 (1%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLN-HY 519
G + PIF + GDYP+ +K +V +S Q SR P + EE ++IR T+D F LN +Y
Sbjct: 1152 GWFAHPIFRN-GDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYY 1210
Query: 518 STFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFY 339
S + ++ + PSY DD + + W + NR PWG +LL I Y
Sbjct: 1211 SRIVQHKTPRL----NPPSYEDDQEMAEEEDPSWPSTAMNRA--APWGTRRLLNWIKEEY 1264
Query: 338 NNVPIIITENGFA-TLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNFEW 165
++PI ITENG T ED DRI + + Y+N L A + DG D+R Y WSLMDNFEW
Sbjct: 1265 GDIPIYITENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEW 1324
Query: 164 MSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLDFDYKPESL 18
++GYT +FGLY VD+++ RT R SA + E++ + + + E L
Sbjct: 1325 LNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGMPLAREDEFL 1373
Score = 131 bits (317), Expect = 2e-30
Identities = 75/219 (34%), Positives = 119/219 (54%), Gaps = 6/219 (2%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G + P+F D GDYP ++ ++ + + ++ PE + E Q ++G++DF GL+HY+
Sbjct: 629 GWFAHPVFVD-GDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYT 687
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
+ L IPSY+ G + W S + ++ PWG +LL+ +S Y
Sbjct: 688 SRLISNAPQNTC---IPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLEYT 744
Query: 335 N--VPIIITENGFATLTG---FEDNDRITHLRLYLNALLDAIKDGS-DIRLYTPWSLMDN 174
VPI + NG F+D+ R+ + Y+N +L AIK+ S D+R Y SL+D
Sbjct: 745 RGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDG 804
Query: 173 FEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
FE SGY+QRFGL+ V++ +RTPRKSA+ F I++
Sbjct: 805 FEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIE 843
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 159 bits (387), Expect = 7e-39
Identities = 84/216 (38%), Positives = 124/216 (57%), Gaps = 4/216 (1%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G + PI+ +GDYP+++K + KSAEQG SR P S +E YI+GTSDF GL H++
Sbjct: 288 GWFANPIY--AGDYPQVMKDYIGRKSAEQGLEMSRLPVFSLQEKSYIKGTSDFLGLGHFT 345
Query: 515 T-FLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFY 339
T ++T RN + PSY +D ++ W + + PWGF +LL Y
Sbjct: 346 TRYITERNYPS---RQGPSYQNDRDLIELVDPNWPDLGSKWLYSVPWGFRRLLNFAQTQY 402
Query: 338 NNVPIIITENGFAT---LTGFEDNDRITHLRLYLNALLDAIKDGSDIRLYTPWSLMDNFE 168
+ PI + ENG + T D RI +L+ Y+N +L AIKDG++I+ YT WSL+D FE
Sbjct: 403 GDPPIYVMENGASQKFHCTQLCDEWRIQYLKGYINEMLKAIKDGANIKGYTSWSLLDKFE 462
Query: 167 WMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIV 60
W GY+ R+G Y V+++ R P+ S +K+I+
Sbjct: 463 WEKGYSDRYGFYYVEFNDRNKPRYPKASVQYYKKII 498
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 159 bits (386), Expect = 9e-39
Identities = 89/229 (38%), Positives = 127/229 (55%), Gaps = 3/229 (1%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLN-HY 519
G + PIF + GDYP+ +K +V +S Q SR P + EE ++IR T+D F LN +Y
Sbjct: 584 GWFAHPIFRN-GDYPDTMKWKVGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYY 642
Query: 518 STFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFY 339
S + ++ + PSY DD + + W + NR PWG +LL I Y
Sbjct: 643 SRIVQHKTPRL----NPPSYEDDQEMAEEEDPSWPSTAMNRA--APWGTRRLLNWIKEEY 696
Query: 338 NNVPIIITENGFA-TLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNFEW 165
++PI ITENG T ED DRI + + Y+N L A + DG D+R Y WSLMDNFEW
Sbjct: 697 GDIPIYITENGVGLTNPNTEDTDRIFYHKTYINEALKAYRLDGIDLRGYVAWSLMDNFEW 756
Query: 164 MSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLDFDYKPESL 18
++GYT +FGLY VD+++ RT R SA + E++ + + + E L
Sbjct: 757 LNGYTVKFGLYHVDFNNTNRPRTARASARYYTEVITNNGMPLAREDEFL 805
Score = 131 bits (317), Expect = 2e-30
Identities = 75/219 (34%), Positives = 119/219 (54%), Gaps = 6/219 (2%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G + P+F D GDYP ++ ++ + + ++ PE + E Q ++G++DF GL+HY+
Sbjct: 61 GWFAHPVFVD-GDYPATLRTQIQQMNRQCSHPVAQLPEFTEAEKQLLKGSADFLGLSHYT 119
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
+ L IPSY+ G + W S + ++ PWG +LL+ +S Y
Sbjct: 120 SRLISNAPQNTC---IPSYDTIGGFSQHVNHVWPQTSSSWIRVVPWGIRRLLQFVSLEYT 176
Query: 335 N--VPIIITENGFATLTG---FEDNDRITHLRLYLNALLDAIKDGS-DIRLYTPWSLMDN 174
VPI + NG F+D+ R+ + Y+N +L AIK+ S D+R Y SL+D
Sbjct: 177 RGKVPIYLAGNGMPIGESENLFDDSLRVDYFNQYINEVLKAIKEDSVDVRSYIARSLIDG 236
Query: 173 FEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
FE SGY+QRFGL+ V++ +RTPRKSA+ F I++
Sbjct: 237 FEGPSGYSQRFGLHHVNFSDSSKSRTPRKSAYFFTSIIE 275
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 157 bits (380), Expect = 5e-38
Identities = 84/219 (38%), Positives = 125/219 (57%), Gaps = 3/219 (1%)
Frame = -3
Query: 689 YGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYSTF 510
+ PIF D GDYPE+VK ++A+ S +QG+ SR PE + EE + I+GT+DFF + +Y+T
Sbjct: 254 FAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTR 312
Query: 509 LTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYNNV 330
L E+ G I D + F+ W + + + PWG KLL+ I + YNN
Sbjct: 313 LIKYQENKKGELGI---LQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNP 367
Query: 329 PIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNFEWMS 159
I ITENGF + +D R + R L AI+ D ++++Y WSL+DNFEW
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 158 GYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLD 42
GY+ RFGL+ VD++ P R P SA + +I+++ L+
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 157 bits (380), Expect = 5e-38
Identities = 84/219 (38%), Positives = 127/219 (57%), Gaps = 3/219 (1%)
Frame = -3
Query: 689 YGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYSTF 510
+ PIF D GDYPE+VK ++A+ S +QG+ SR PE + EE + I+GT+DFF + +Y+T
Sbjct: 254 FAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTR 312
Query: 509 LTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYNNV 330
L E+ G E+ + D + F+ W + + + PWG KLL+ I + YNN
Sbjct: 313 LIKYQENKKG--ELGTL-QDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNP 367
Query: 329 PIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNFEWMS 159
I ITENGF + +D R + R L AI+ D ++++Y WSL+DNFEW
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 158 GYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLD 42
GY+ RFGL+ VD++ P R P SA + +I+++ L+
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 157 bits (380), Expect = 5e-38
Identities = 84/219 (38%), Positives = 125/219 (57%), Gaps = 3/219 (1%)
Frame = -3
Query: 689 YGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYSTF 510
+ PIF D GDYPE+VK ++A+ S +QG+ SR PE + EE + I+GT+DFF + +Y+T
Sbjct: 254 FAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTR 312
Query: 509 LTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYNNV 330
L E+ G I D + F+ W + + + PWG KLL+ I + YNN
Sbjct: 313 LIKYQENKKGELGI---LQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNP 367
Query: 329 PIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNFEWMS 159
I ITENGF + +D R + R L AI+ D ++++Y WSL+DNFEW
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 158 GYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLD 42
GY+ RFGL+ VD++ P R P SA + +I+++ L+
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 157 bits (380), Expect = 5e-38
Identities = 84/219 (38%), Positives = 125/219 (57%), Gaps = 3/219 (1%)
Frame = -3
Query: 689 YGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYSTF 510
+ PIF D GDYPE+VK ++A+ S +QG+ SR PE + EE + I+GT+DFF + +Y+T
Sbjct: 254 FAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTR 312
Query: 509 LTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYNNV 330
L E+ G I D + F+ W + + + PWG KLL+ I + YNN
Sbjct: 313 LIKYQENKKGELGI---LQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNP 367
Query: 329 PIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNFEWMS 159
I ITENGF + +D R + R L AI+ D ++++Y WSL+DNFEW
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 158 GYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLD 42
GY+ RFGL+ VD++ P R P SA + +I+++ L+
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 157 bits (380), Expect = 5e-38
Identities = 84/219 (38%), Positives = 125/219 (57%), Gaps = 3/219 (1%)
Frame = -3
Query: 689 YGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYSTF 510
+ PIF D GDYPE+VK ++A+ S +QG+ SR PE + EE + I+GT+DFF + +Y+T
Sbjct: 254 FAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTR 312
Query: 509 LTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYNNV 330
L E+ G I D + F+ W + + + PWG KLL+ I + YNN
Sbjct: 313 LIKYQENKKGELGI---LQDAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNP 367
Query: 329 PIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNFEWMS 159
I ITENGF + +D R + R L AI+ D ++++Y WSL+DNFEW
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 158 GYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLD 42
GY+ RFGL+ VD++ P R P SA + +I+++ L+
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 153 bits (370), Expect = 8e-37
Identities = 83/219 (37%), Positives = 124/219 (56%), Gaps = 3/219 (1%)
Frame = -3
Query: 689 YGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYSTF 510
+ PIF D GDYPE+VK ++A+ S +QG+ SR PE + EE + I+GT+DFF + + +T
Sbjct: 254 FAKPIFID-GDYPEVVKSQIASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYCTTR 312
Query: 509 LTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYNNV 330
L E+ G I D + F+ W + + + PWG KLL+ I + YNN
Sbjct: 313 LIKYQENKRGELGILQ---DAEIEFFPDPSWK--NVDWIYVVPWGVCKLLKYIKDTYNNP 367
Query: 329 PIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNFEWMS 159
I ITENGF + +D R + R L AI+ D ++++Y WSL+DNFEW
Sbjct: 368 VIYITENGFPQSDPAPLDDTQRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQ 427
Query: 158 GYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLD 42
GY+ RFGL+ VD++ P R P SA + +I+++ L+
Sbjct: 428 GYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 466
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 76.6 bits (180), Expect = 8e-14
Identities = 40/98 (40%), Positives = 60/98 (61%), Gaps = 3/98 (3%)
Frame = -3
Query: 341 YNNVPIIITENGFATLTGF--EDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNF 171
YNN I+I ENG+ T + ED I ++ +L+ +L AI+ D + YT WSL+D F
Sbjct: 407 YNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGF 466
Query: 170 EWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
EW YT R GL+ VD++S + R P+ SA +K+I++
Sbjct: 467 EWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 1/219 (0%)
Frame = -3
Query: 689 YGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYSTF 510
+ P+F +GDYP +++ +A+K +G S P L+ E + ++GT DF LNH++T
Sbjct: 772 FAEPLFK-TGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTR 829
Query: 509 LTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYNNV 330
+E + G Y+ D + F ++ + S R+ PWG KLLR + Y ++
Sbjct: 830 FVM-HEQLAG----SRYDSDRDIQFL-QDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDM 883
Query: 329 PIIITENGFATLTGFEDNDRITHLRLYLNALLDA-IKDGSDIRLYTPWSLMDNFEWMSGY 153
I IT +G +D R +L YL +L A + D I+ Y + L +
Sbjct: 884 DIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKS----- 938
Query: 152 TQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLDFD 36
RFG + D+ + + S + +++ SR F+
Sbjct: 939 KPRFGFFTSDFKA-------KSSIQFYNKVISSRGFPFE 970
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 76.6 bits (180), Expect = 8e-14
Identities = 40/98 (40%), Positives = 60/98 (61%), Gaps = 3/98 (3%)
Frame = -3
Query: 341 YNNVPIIITENGFATLTGF--EDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNF 171
YNN I+I ENG+ T + ED I ++ +L+ +L AI+ D + YT WSL+D F
Sbjct: 407 YNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGF 466
Query: 170 EWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
EW YT R GL+ VD++S + R P+ SA +K+I++
Sbjct: 467 EWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 1/219 (0%)
Frame = -3
Query: 689 YGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYSTF 510
+ P+F +GDYP +++ +A+K +G S P L+ E + ++GT DF LNH++T
Sbjct: 772 FAEPLFK-TGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTR 829
Query: 509 LTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYNNV 330
+E + G Y+ D + F ++ + S R+ PWG KLLR + Y ++
Sbjct: 830 FVM-HEQLAG----SRYDSDRDIQFL-QDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDM 883
Query: 329 PIIITENGFATLTGFEDNDRITHLRLYLNALLDA-IKDGSDIRLYTPWSLMDNFEWMSGY 153
I IT +G +D R +L YL +L A + D I+ Y + L +
Sbjct: 884 DIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKS----- 938
Query: 152 TQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLDFD 36
RFG + D+ + + S + +++ SR F+
Sbjct: 939 KPRFGFFTSDFKA-------KSSIQFYNKVISSRGFPFE 970
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 76.6 bits (180), Expect = 8e-14
Identities = 40/98 (40%), Positives = 60/98 (61%), Gaps = 3/98 (3%)
Frame = -3
Query: 341 YNNVPIIITENGFATLTGF--EDNDRITHLRLYLNALLDAIK-DGSDIRLYTPWSLMDNF 171
YNN I+I ENG+ T + ED I ++ +L+ +L AI+ D + YT WSL+D F
Sbjct: 407 YNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRVFGYTAWSLLDGF 466
Query: 170 EWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
EW YT R GL+ VD++S + R P+ SA +K+I++
Sbjct: 467 EWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIR 504
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 1/219 (0%)
Frame = -3
Query: 689 YGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYSTF 510
+ P+F +GDYP +++ +A+K +G S P L+ E + ++GT DF LNH++T
Sbjct: 772 FAEPLFK-TGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTR 829
Query: 509 LTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYNNV 330
+E + G Y+ D + F ++ + S R+ PWG KLLR + Y ++
Sbjct: 830 FVM-HEQLAG----SRYDSDRDIQFL-QDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDM 883
Query: 329 PIIITENGFATLTGFEDNDRITHLRLYLNALLDA-IKDGSDIRLYTPWSLMDNFEWMSGY 153
I IT +G +D R +L YL +L A + D I+ Y + L +
Sbjct: 884 DIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKS----- 938
Query: 152 TQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLDFD 36
RFG + D+ + + S + +++ SR F+
Sbjct: 939 KPRFGFFTSDFKA-------KSSIQFYNKVISSRGFPFE 970
>BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein.
Length = 305
Score = 72.9 bits (171), Expect = 1e-12
Identities = 59/219 (26%), Positives = 102/219 (46%), Gaps = 1/219 (0%)
Frame = -3
Query: 689 YGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYSTF 510
+ P+F +GDYP +++ +A+K +G S P L+ E + ++GT DF LNH++T
Sbjct: 33 FAEPLFK-TGDYPAAMREYIASKH-RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTR 90
Query: 509 LTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYNNV 330
+E + G Y+ D + F ++ + S R+ PWG KLLR + Y ++
Sbjct: 91 FVM-HEQLAG----SRYDSDRDIQFL-QDITRLSSPTRLAVIPWGVRKLLRWVRRNYGDM 144
Query: 329 PIIITENGFATLTGFEDNDRITHLRLYLNALLDA-IKDGSDIRLYTPWSLMDNFEWMSGY 153
I IT +G +D R +L YL +L A + D I+ Y + L +
Sbjct: 145 DIYITASGIDDQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAEEKS----- 199
Query: 152 TQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLDFD 36
RFG + D+ + + S + +++ SR F+
Sbjct: 200 KPRFGFFTSDFKA-------KSSIQFYNKVISSRGFPFE 231
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 72.1 bits (169), Expect = 2e-12
Identities = 65/216 (30%), Positives = 101/216 (46%), Gaps = 2/216 (0%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G PIF SGDYP +++ + ++ FL F E +E + I+GT DF L+HY+
Sbjct: 485 GWLAEPIF-GSGDYPWVMRDWLNQRN---NFLLPYFTE---DEKKLIQGTFDFLALSHYT 537
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
T L + + YND + V W + S ++V PWG K+L + Y
Sbjct: 538 TILVDSEKE-----DPIKYNDYLEVQEMTDITW-LNSPSQVAVVPWGLRKVLNWLKFKYG 591
Query: 335 NVPIIITENGFAT-LTGFEDNDRITHLRLYLNALLDA-IKDGSDIRLYTPWSLMDNFEWM 162
++P+ I NG L +D R+ +++ Y+N L A I DG ++ Y +S D
Sbjct: 592 DLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILDGINLCGYFAYSFNDR---- 647
Query: 161 SGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKS 54
RFGLY D E P+ S +++I+ S
Sbjct: 648 --TAPRFGLYRYAADQFE----PKASMKHYRKIIDS 677
Score = 71.7 bits (168), Expect = 2e-12
Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 3/107 (2%)
Frame = -3
Query: 368 KLLRQISNFYNNVPIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLY 198
+LL I +N+ I I ENG+ + T +D + +L+ ++ L AIK DG D+ Y
Sbjct: 123 QLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGY 182
Query: 197 TPWSLMDNFEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
T WSLMD FEW GY+ R GL+ VD+ S + P+ SA ++++++
Sbjct: 183 TAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 229
Score = 37.1 bits (82), Expect = 0.060
Identities = 21/56 (37%), Positives = 30/56 (53%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGL 528
G + P+F D GDYPE +K L S P+ + E ++I+GT+DFF L
Sbjct: 52 GWFAKPVFID-GDYPESMKNN----------LSSILPDFTESEKKFIKGTADFFAL 96
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 72.1 bits (169), Expect = 2e-12
Identities = 65/216 (30%), Positives = 101/216 (46%), Gaps = 2/216 (0%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G PIF SGDYP +++ + ++ FL F E +E + I+GT DF L+HY+
Sbjct: 758 GWLAEPIF-GSGDYPWVMRDWLNQRN---NFLLPYFTE---DEKKLIQGTFDFLALSHYT 810
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
T L + + YND + V W + S ++V PWG K+L + Y
Sbjct: 811 TILVDSEKE-----DPIKYNDYLEVQEMTDITW-LNSPSQVAVVPWGLRKVLNWLKFKYG 864
Query: 335 NVPIIITENGFAT-LTGFEDNDRITHLRLYLNALLDA-IKDGSDIRLYTPWSLMDNFEWM 162
++P+ I NG L +D R+ +++ Y+N L A I DG ++ Y +S D
Sbjct: 865 DLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILDGINLCGYFAYSFNDR---- 920
Query: 161 SGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKS 54
RFGLY D E P+ S +++I+ S
Sbjct: 921 --TAPRFGLYRYAADQFE----PKASMKHYRKIIDS 950
Score = 71.7 bits (168), Expect = 2e-12
Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 3/107 (2%)
Frame = -3
Query: 368 KLLRQISNFYNNVPIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLY 198
+LL I +N+ I I ENG+ + T +D + +L+ ++ L AIK DG D+ Y
Sbjct: 396 QLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGY 455
Query: 197 TPWSLMDNFEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
T WSLMD FEW GY+ R GL+ VD+ S + P+ SA ++++++
Sbjct: 456 TAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 502
Score = 37.1 bits (82), Expect = 0.060
Identities = 21/56 (37%), Positives = 30/56 (53%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGL 528
G + P+F D GDYPE +K L S P+ + E ++I+GT+DFF L
Sbjct: 325 GWFAKPVFID-GDYPESMKNN----------LSSILPDFTESEKKFIKGTADFFAL 369
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) protein.
Length = 1012
Score = 72.1 bits (169), Expect = 2e-12
Identities = 65/216 (30%), Positives = 101/216 (46%), Gaps = 2/216 (0%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G PIF SGDYP +++ + ++ FL F E +E + I+GT DF L+HY+
Sbjct: 758 GWLAEPIF-GSGDYPWVMRDWLNQRN---NFLLPYFTE---DEKKLIQGTFDFLALSHYT 810
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
T L + + YND + V W + S ++V PWG K+L + Y
Sbjct: 811 TILVDSEKE-----DPIKYNDYLEVQEMTDITW-LNSPSQVAVVPWGLRKVLNWLKFKYG 864
Query: 335 NVPIIITENGFAT-LTGFEDNDRITHLRLYLNALLDA-IKDGSDIRLYTPWSLMDNFEWM 162
++P+ I NG L +D R+ +++ Y+N L A I DG ++ Y +S D
Sbjct: 865 DLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILDGINLCGYFAYSFNDR---- 920
Query: 161 SGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKS 54
RFGLY D E P+ S +++I+ S
Sbjct: 921 --TAPRFGLYRYAADQFE----PKASMKHYRKIIDS 950
Score = 71.7 bits (168), Expect = 2e-12
Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 3/107 (2%)
Frame = -3
Query: 368 KLLRQISNFYNNVPIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLY 198
+LL I +N+ I I ENG+ + T +D + +L+ ++ L AIK DG D+ Y
Sbjct: 396 QLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGY 455
Query: 197 TPWSLMDNFEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
T WSLMD FEW GY+ R GL+ VD+ S + P+ SA ++++++
Sbjct: 456 TAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 502
Score = 37.1 bits (82), Expect = 0.060
Identities = 21/56 (37%), Positives = 30/56 (53%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGL 528
G + P+F D GDYPE +K L S P+ + E ++I+GT+DFF L
Sbjct: 325 GWFAKPVFID-GDYPESMKNN----------LSSILPDFTESEKKFIKGTADFFAL 369
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 72.1 bits (169), Expect = 2e-12
Identities = 65/216 (30%), Positives = 101/216 (46%), Gaps = 2/216 (0%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGLNHYS 516
G PIF SGDYP +++ + ++ FL F E +E + I+GT DF L+HY+
Sbjct: 758 GWLAEPIF-GSGDYPWVMRDWLNQRN---NFLLPYFTE---DEKKLIQGTFDFLALSHYT 810
Query: 515 TFLTYRNESVVGYYEIPSYNDDVGVLFYDKEEWSIGSHNRVKTTPWGFYKLLRQISNFYN 336
T L + + YND + V W + S ++V PWG K+L + Y
Sbjct: 811 TILVDSEKE-----DPIKYNDYLEVQEMTDITW-LNSPSQVAVVPWGLRKVLNWLKFKYG 864
Query: 335 NVPIIITENGFAT-LTGFEDNDRITHLRLYLNALLDA-IKDGSDIRLYTPWSLMDNFEWM 162
++P+ I NG L +D R+ +++ Y+N L A I DG ++ Y +S D
Sbjct: 865 DLPMYIISNGIDDGLHAEDDQLRVYYMQNYINEALKAHILDGINLCGYFAYSFNDR---- 920
Query: 161 SGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKS 54
RFGLY D E P+ S +++I+ S
Sbjct: 921 --TAPRFGLYRYAADQFE----PKASMKHYRKIIDS 950
Score = 71.7 bits (168), Expect = 2e-12
Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 3/107 (2%)
Frame = -3
Query: 368 KLLRQISNFYNNVPIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLY 198
+LL I +N+ I I ENG+ + T +D + +L+ ++ L AIK DG D+ Y
Sbjct: 396 QLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGY 455
Query: 197 TPWSLMDNFEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
T WSLMD FEW GY+ R GL+ VD+ S + P+ SA ++++++
Sbjct: 456 TAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 502
Score = 37.1 bits (82), Expect = 0.060
Identities = 21/56 (37%), Positives = 30/56 (53%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGL 528
G + P+F D GDYPE +K L S P+ + E ++I+GT+DFF L
Sbjct: 325 GWFAKPVFID-GDYPESMKNN----------LSSILPDFTESEKKFIKGTADFFAL 369
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 71.7 bits (168), Expect = 2e-12
Identities = 40/107 (37%), Positives = 63/107 (58%), Gaps = 3/107 (2%)
Frame = -3
Query: 368 KLLRQISNFYNNVPIIITENGF--ATLTGFEDNDRITHLRLYLNALLDAIK-DGSDIRLY 198
+LL I +N+ I I ENG+ + T +D + +L+ ++ L AIK DG D+ Y
Sbjct: 396 QLLSWIDLEFNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIKLDGVDVIGY 455
Query: 197 TPWSLMDNFEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVK 57
T WSLMD FEW GY+ R GL+ VD+ S + P+ SA ++++++
Sbjct: 456 TAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIE 502
Score = 37.1 bits (82), Expect = 0.060
Identities = 21/56 (37%), Positives = 30/56 (53%)
Frame = -3
Query: 695 GQYGXPIFTDSGDYPEIVKQRVAAKSAEQGFLRSRFPELSPEEVQYIRGTSDFFGL 528
G + P+F D GDYPE +K L S P+ + E ++I+GT+DFF L
Sbjct: 325 GWFAKPVFID-GDYPESMKNN----------LSSILPDFTESEKKFIKGTADFFAL 369
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 64.1 bits (149), Expect = 5e-10
Identities = 25/60 (41%), Positives = 40/60 (66%)
Frame = -3
Query: 221 DGSDIRLYTPWSLMDNFEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLD 42
D ++++Y WSL+DNFEW GY+ RFGL+ VD++ P R P SA + +I+++ L+
Sbjct: 100 DKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 64.1 bits (149), Expect = 5e-10
Identities = 25/60 (41%), Positives = 40/60 (66%)
Frame = -3
Query: 221 DGSDIRLYTPWSLMDNFEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLD 42
D ++++Y WSL+DNFEW GY+ RFGL+ VD++ P R P SA + +I+++ L+
Sbjct: 100 DKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 64.1 bits (149), Expect = 5e-10
Identities = 25/60 (41%), Positives = 40/60 (66%)
Frame = -3
Query: 221 DGSDIRLYTPWSLMDNFEWMSGYTQRFGLYEVDYDSPELTRTPRKSAFIFKEIVKSRTLD 42
D ++++Y WSL+DNFEW GY+ RFGL+ VD++ P R P SA + +I+++ L+
Sbjct: 100 DKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNGLE 159
>BC036025-1|AAH36025.1| 1070|Homo sapiens protocadherin 8 protein.
Length = 1070
Score = 30.3 bits (65), Expect = 6.9
Identities = 17/56 (30%), Positives = 28/56 (50%)
Frame = +1
Query: 151 VYPDIHSKLSIKLQGVYSLISDPSLIASRRAFKYNLRCVIRSLSSKPVRVAKPFSV 318
+Y H +L G Y +++ SL R A +YNL V + P+R +P++V
Sbjct: 431 LYGHEHFRLQPAYAGSYLVVTAASLDRERIA-EYNLTLVAEDRGAPPLRTVRPYTV 485
>AY013873-1|AAK21986.1| 973|Homo sapiens protocadherin ARCADLIN
protein.
Length = 973
Score = 30.3 bits (65), Expect = 6.9
Identities = 17/56 (30%), Positives = 28/56 (50%)
Frame = +1
Query: 151 VYPDIHSKLSIKLQGVYSLISDPSLIASRRAFKYNLRCVIRSLSSKPVRVAKPFSV 318
+Y H +L G Y +++ SL R A +YNL V + P+R +P++V
Sbjct: 431 LYGHEHFRLQPAYAGSYLVVTAASLDRERIA-EYNLTLVAEDRGAPPLRTVRPYTV 485
>AL139085-5|CAI14111.1| 973|Homo sapiens protocadherin 8 protein.
Length = 973
Score = 30.3 bits (65), Expect = 6.9
Identities = 17/56 (30%), Positives = 28/56 (50%)
Frame = +1
Query: 151 VYPDIHSKLSIKLQGVYSLISDPSLIASRRAFKYNLRCVIRSLSSKPVRVAKPFSV 318
+Y H +L G Y +++ SL R A +YNL V + P+R +P++V
Sbjct: 431 LYGHEHFRLQPAYAGSYLVVTAASLDRERIA-EYNLTLVAEDRGAPPLRTVRPYTV 485
>AL139085-4|CAI14110.1| 1070|Homo sapiens protocadherin 8 protein.
Length = 1070
Score = 30.3 bits (65), Expect = 6.9
Identities = 17/56 (30%), Positives = 28/56 (50%)
Frame = +1
Query: 151 VYPDIHSKLSIKLQGVYSLISDPSLIASRRAFKYNLRCVIRSLSSKPVRVAKPFSV 318
+Y H +L G Y +++ SL R A +YNL V + P+R +P++V
Sbjct: 431 LYGHEHFRLQPAYAGSYLVVTAASLDRERIA-EYNLTLVAEDRGAPPLRTVRPYTV 485
>AF061573-1|AAC70009.2| 1070|Homo sapiens protocadherin protein.
Length = 1070
Score = 30.3 bits (65), Expect = 6.9
Identities = 17/56 (30%), Positives = 28/56 (50%)
Frame = +1
Query: 151 VYPDIHSKLSIKLQGVYSLISDPSLIASRRAFKYNLRCVIRSLSSKPVRVAKPFSV 318
+Y H +L G Y +++ SL R A +YNL V + P+R +P++V
Sbjct: 431 LYGHEHFRLQPAYAGSYLVVTAASLDRERIA-EYNLTLVAEDRGAPPLRTVRPYTV 485
>BC106021-1|AAI06022.1| 469|Homo sapiens SBNO2 protein protein.
Length = 469
Score = 29.9 bits (64), Expect = 9.1
Identities = 11/30 (36%), Positives = 16/30 (53%)
Frame = -1
Query: 169 NGCLDIRKDLDFMKLITTVQNLHGRRENLL 80
NGCLD+ KD K + + L ++N L
Sbjct: 57 NGCLDVEKDCSITKFLNRILGLEVHKQNAL 86
>AK074102-1|BAB84928.1| 1269|Homo sapiens FLJ00173 protein protein.
Length = 1269
Score = 29.9 bits (64), Expect = 9.1
Identities = 11/30 (36%), Positives = 16/30 (53%)
Frame = -1
Query: 169 NGCLDIRKDLDFMKLITTVQNLHGRRENLL 80
NGCLD+ KD K + + L ++N L
Sbjct: 853 NGCLDVEKDCSITKFLNRILGLEVHKQNAL 882
>AC005390-2|AAC28919.1| 1384|Homo sapiens R31180_1 protein.
Length = 1384
Score = 29.9 bits (64), Expect = 9.1
Identities = 11/30 (36%), Positives = 16/30 (53%)
Frame = -1
Query: 169 NGCLDIRKDLDFMKLITTVQNLHGRRENLL 80
NGCLD+ KD K + + L ++N L
Sbjct: 961 NGCLDVEKDCSITKFLNRILGLEVHKQNAL 990
>AB023180-1|BAA76807.2| 1391|Homo sapiens KIAA0963 protein protein.
Length = 1391
Score = 29.9 bits (64), Expect = 9.1
Identities = 11/30 (36%), Positives = 16/30 (53%)
Frame = -1
Query: 169 NGCLDIRKDLDFMKLITTVQNLHGRRENLL 80
NGCLD+ KD K + + L ++N L
Sbjct: 979 NGCLDVEKDCSITKFLNRILGLEVHKQNAL 1008
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 94,129,544
Number of Sequences: 237096
Number of extensions: 1894007
Number of successful extensions: 3852
Number of sequences better than 10.0: 32
Number of HSP's better than 10.0 without gapping: 3674
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3793
length of database: 76,859,062
effective HSP length: 88
effective length of database: 55,994,614
effective search space used: 8063224416
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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