Last updated: 2022/11/18
BLASTX 2.2.12 [Aug-07-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= fmgV11l16r
(649 letters)
Database: human
237,096 sequences; 76,859,062 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosid... 160 3e-39
AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosid... 160 3e-39
AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosid... 160 3e-39
AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic beta-glucosid... 160 3e-39
AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosid... 158 1e-38
AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosid... 158 2e-38
X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for ... 151 2e-36
M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolas... 151 2e-36
AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein. 151 2e-36
AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein. 136 6e-32
AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin hydro... 126 7e-29
Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein. 81 3e-15
AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein. 81 3e-15
AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL) pro... 81 3e-15
AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL) pro... 81 3e-15
AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein. 81 3e-15
BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein. 79 1e-14
BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein. 79 1e-14
AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protei... 79 1e-14
BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein. 74 5e-13
BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein. 74 5e-13
BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein. 74 5e-13
BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein. 59 2e-08
U83246-1|AAC15920.1| 537|Homo sapiens copine I protein. 35 0.29
CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein. 35 0.29
BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein. 35 0.29
AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein. 35 0.29
AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein. 35 0.29
AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein. 35 0.29
AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein. 35 0.29
BC066597-1|AAH66597.1| 537|Homo sapiens copine III protein. 33 1.2
BC036242-1|AAH36242.1| 537|Homo sapiens copine III protein. 33 1.2
AF077226-1|AAD46074.2| 537|Homo sapiens copine III protein. 33 1.2
AB014536-1|BAA31611.2| 540|Homo sapiens KIAA0636 protein protein. 33 1.2
BC053658-1|AAH53658.1| 548|Homo sapiens CPNE2 protein protein. 30 6.2
AF542551-1|AAQ09534.1| 446|Homo sapiens unknown protein. 30 6.2
AF492484-1|AAO85483.1| 548|Homo sapiens copine III-like related... 30 6.2
>BC101829-1|AAI01830.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 160 bits (389), Expect = 3e-39
Identities = 77/197 (39%), Positives = 113/197 (57%), Gaps = 1/197 (0%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
+A S K+GYP SR+PEFT+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQD 329
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 274 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 98
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 97 TPRKSAFVYQGDLEKQG 47
P SA Y + G
Sbjct: 448 VPYTSAKEYAKIIRNNG 464
>AF323990-1|AAL37305.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 160 bits (389), Expect = 3e-39
Identities = 77/197 (39%), Positives = 113/197 (57%), Gaps = 1/197 (0%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
+A S K+GYP SR+PEFT+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQD 329
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 274 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 98
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 97 TPRKSAFVYQGDLEKQG 47
P SA Y + G
Sbjct: 448 VPYTSAKEYAKIIRNNG 464
>AF317840-1|AAG39217.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 160 bits (389), Expect = 3e-39
Identities = 77/197 (39%), Positives = 113/197 (57%), Gaps = 1/197 (0%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
+A S K+GYP SR+PEFT+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQD 329
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 274 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 98
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 97 TPRKSAFVYQGDLEKQG 47
P SA Y + G
Sbjct: 448 VPYTSAKEYAKIIRNNG 464
>AB017913-1|BAB18741.1| 469|Homo sapiens cytosolic
beta-glucosidase-like protein-1 protein.
Length = 469
Score = 160 bits (389), Expect = 3e-39
Identities = 77/197 (39%), Positives = 113/197 (57%), Gaps = 1/197 (0%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
+A S K+GYP SR+PEFT+EE+++++G +DFF V +YT L+ E + + + IL D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGILQD 329
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 274 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 98
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 97 TPRKSAFVYQGDLEKQG 47
P SA Y + G
Sbjct: 448 VPYTSAKEYAKIIRNNG 464
>AJ278964-1|CAC08178.1| 469|Homo sapiens cytosolic beta-glucosidase
protein.
Length = 469
Score = 158 bits (384), Expect = 1e-38
Identities = 76/197 (38%), Positives = 112/197 (56%), Gaps = 1/197 (0%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
+A S K+GYP SR+PEFT+EE+++++G +DFF V +YT L+ E + + + L D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYYTTRLIKYQE--NKKGELGTLQD 329
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 274 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 98
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 97 TPRKSAFVYQGDLEKQG 47
P SA Y + G
Sbjct: 448 VPYTSAKEYAKIIRNNG 464
>AK222963-1|BAD96683.1| 469|Homo sapiens cytosolic beta-glucosidase
variant protein.
Length = 469
Score = 158 bits (383), Expect = 2e-38
Identities = 77/197 (39%), Positives = 112/197 (56%), Gaps = 1/197 (0%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
+A S K+GYP SR+PEFT+EE+++++G +DFF V + T L+ E + R + IL D
Sbjct: 272 IASMSQKQGYPSSRLPEFTEEEKKMIKGTADFFAVQYCTTRLIKYQE--NKRGELGILQD 329
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
+ + P W W+ + P + L Y++ YN+P+ YITENG+ L D
Sbjct: 330 AEIEFFPDPSWKNVD--WIYVVPWGVCKLLKYIKDTYNNPVIYITENGFPQSDPAPLDDT 387
Query: 274 DRIRYYRAALESVLDCLDAG-IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPR 98
R Y+R + + + + L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR
Sbjct: 388 QRWEYFRQTFQELFKAIQLDKVNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPR 447
Query: 97 TPRKSAFVYQGDLEKQG 47
P SA Y + G
Sbjct: 448 VPYTSAKEYAKIIRNNG 464
>X07994-1|CAA30801.1| 1927|Homo sapiens protein ( Human mRNA for
lactase-phlorizin hydrolase LPH (EC 3.2.1.23-62). ).
Length = 1927
Score = 151 bits (367), Expect = 2e-36
Identities = 74/188 (39%), Positives = 102/188 (54%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
+ ++S G SR+PEFT+ E+ + G DFFG NHYT L + + D
Sbjct: 1646 IRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA--D 1703
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
V + WP S S+WL ++P L +L++ YNDP Y+TENG S L D
Sbjct: 1704 RGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDT 1763
Query: 274 DRIRYYRAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRT 95
RI Y R + L + + L+GY WS MDNFEW G++ERFGL+ V++SDP+ PR
Sbjct: 1764 ARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRI 1823
Query: 94 PRKSAFVY 71
P+ SA Y
Sbjct: 1824 PKASAKFY 1831
Score = 126 bits (304), Expect = 7e-29
Identities = 66/192 (34%), Positives = 113/192 (58%), Gaps = 5/192 (2%)
Frame = -1
Query: 607 YPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPP 428
+P +++PEFT+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 658 HPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNH 715
Query: 427 EWPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRY 260
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y
Sbjct: 716 VWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDY 774
Query: 259 YRAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKS 83
+ + VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKS
Sbjct: 775 FNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKS 834
Query: 82 AFVYQGDLEKQG 47
A+ + +EK G
Sbjct: 835 AYFFTSIIEKNG 846
Score = 125 bits (301), Expect = 2e-28
Identities = 75/198 (37%), Positives = 102/198 (51%), Gaps = 2/198 (1%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
V +S + SR+P FT+EE+ +R +D F +N Y +V + P+ D
Sbjct: 1172 VGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DD 1229
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
+ P WP +A +P L ++++ Y D YITENG N D
Sbjct: 1230 QEMAEEEDPSWPSTAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDT 1286
Query: 274 DRIRYYRAALESVLDC--LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARP 101
DRI Y++ + L LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RP
Sbjct: 1287 DRIFYHKTYINEALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRP 1345
Query: 100 RTPRKSAFVYQGDLEKQG 47
RT R SA Y + G
Sbjct: 1346 RTARASARYYTEVITNNG 1363
>M61850-1|AAA59504.1| 1927|Homo sapiens lactase phlorizinhydrolase
protein.
Length = 1927
Score = 151 bits (367), Expect = 2e-36
Identities = 74/188 (39%), Positives = 102/188 (54%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
+ ++S G SR+PEFT+ E+ + G DFFG NHYT L + + D
Sbjct: 1646 IRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA--D 1703
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
V + WP S S+WL ++P L +L++ YNDP Y+TENG S L D
Sbjct: 1704 RGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDT 1763
Query: 274 DRIRYYRAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRT 95
RI Y R + L + + L+GY WS MDNFEW G++ERFGL+ V++SDP+ PR
Sbjct: 1764 ARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRI 1823
Query: 94 PRKSAFVY 71
P+ SA Y
Sbjct: 1824 PKASAKFY 1831
Score = 126 bits (304), Expect = 7e-29
Identities = 66/192 (34%), Positives = 113/192 (58%), Gaps = 5/192 (2%)
Frame = -1
Query: 607 YPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPP 428
+P +++PEFT+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 658 HPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNH 715
Query: 427 EWPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRY 260
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y
Sbjct: 716 VWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDY 774
Query: 259 YRAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKS 83
+ + VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKS
Sbjct: 775 FNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKS 834
Query: 82 AFVYQGDLEKQG 47
A+ + +EK G
Sbjct: 835 AYFFTSIIEKNG 846
Score = 125 bits (301), Expect = 2e-28
Identities = 75/198 (37%), Positives = 102/198 (51%), Gaps = 2/198 (1%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
V +S + SR+P FT+EE+ +R +D F +N Y +V + P+ D
Sbjct: 1172 VGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DD 1229
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
+ P WP +A +P L ++++ Y D YITENG N D
Sbjct: 1230 QEMAEEEDPSWPSTAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDT 1286
Query: 274 DRIRYYRAALESVLDC--LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARP 101
DRI Y++ + L LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RP
Sbjct: 1287 DRIFYHKTYINEALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRP 1345
Query: 100 RTPRKSAFVYQGDLEKQG 47
RT R SA Y + G
Sbjct: 1346 RTARASARYYTEVITNNG 1363
>AC011893-3|AAX88924.1| 1927|Homo sapiens unknown protein.
Length = 1927
Score = 151 bits (367), Expect = 2e-36
Identities = 74/188 (39%), Positives = 102/188 (54%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
+ ++S G SR+PEFT+ E+ + G DFFG NHYT L + + D
Sbjct: 1646 IRDRSLAAGLNKSRLPEFTESEKRRINGTYDFFGFNHYTTVLAYNLNYATAISSFDA--D 1703
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
V + WP S S+WL ++P L +L++ YNDP Y+TENG S L D
Sbjct: 1704 RGVASIADRSWPDSGSFWLKMTPFGFRRILNWLKEEYNDPPIYVTENGVSQREETDLNDT 1763
Query: 274 DRIRYYRAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRT 95
RI Y R + L + + L+GY WS MDNFEW G++ERFGL+ V++SDP+ PR
Sbjct: 1764 ARIYYLRTYINEALKAVQDKVDLRGYTVWSAMDNFEWATGFSERFGLHFVNYSDPSLPRI 1823
Query: 94 PRKSAFVY 71
P+ SA Y
Sbjct: 1824 PKASAKFY 1831
Score = 126 bits (304), Expect = 7e-29
Identities = 66/192 (34%), Positives = 113/192 (58%), Gaps = 5/192 (2%)
Frame = -1
Query: 607 YPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPP 428
+P +++PEFT+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 658 HPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNH 715
Query: 427 EWPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRY 260
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y
Sbjct: 716 VWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDY 774
Query: 259 YRAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKS 83
+ + VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKS
Sbjct: 775 FNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKS 834
Query: 82 AFVYQGDLEKQG 47
A+ + +EK G
Sbjct: 835 AYFFTSIIEKNG 846
Score = 125 bits (301), Expect = 2e-28
Identities = 75/198 (37%), Positives = 102/198 (51%), Gaps = 2/198 (1%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
V +S + SR+P FT+EE+ +R +D F +N Y +V + P+ D
Sbjct: 1172 VGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DD 1229
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
+ P WP +A +P L ++++ Y D YITENG N D
Sbjct: 1230 QEMAEEEDPSWPSTAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDT 1286
Query: 274 DRIRYYRAALESVLDC--LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARP 101
DRI Y++ + L LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RP
Sbjct: 1287 DRIFYHKTYINEALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRP 1345
Query: 100 RTPRKSAFVYQGDLEKQG 47
RT R SA Y + G
Sbjct: 1346 RTARASARYYTEVITNNG 1363
>AY358729-1|AAQ89091.1| 567|Homo sapiens KPVW3022 protein.
Length = 567
Score = 136 bits (329), Expect = 6e-32
Identities = 66/193 (34%), Positives = 104/193 (53%), Gaps = 2/193 (1%)
Frame = -1
Query: 640 EIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTG-FLVSANEQISDRPTIPI 464
+ + KSA++G SR+P F+ +E+ ++G SDF G+ H+T ++ N P+
Sbjct: 305 DYIGRKSAEQGLEMSRLPVFSLQEKSYIKGTSDFLGLGHFTTRYITERNYPSRQGPSYQN 364
Query: 463 LPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSP-PTNG 287
D+ + P WP S WL P L + Q +Y DP Y+ ENG S
Sbjct: 365 DRDLI--ELVDPNWPDLGSKWLYSVPWGFRRLLNFAQTQYGDPPIYVMENGASQKFHCTQ 422
Query: 286 LLDDDRIRYYRAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPA 107
L D+ RI+Y + + +L + G +KGY +WSL+D FEW +GY++R+G Y V+F+D
Sbjct: 423 LCDEWRIQYLKGYINEMLKAIKDGANIKGYTSWSLLDKFEWEKGYSDRYGFYYVEFNDRN 482
Query: 106 RPRTPRKSAFVYQ 68
+PR P+ S Y+
Sbjct: 483 KPRYPKASVQYYK 495
>AY191611-1|AAP12677.1| 1003|Homo sapiens lactase-phlorizin
hydrolase-1 protein.
Length = 1003
Score = 126 bits (304), Expect = 7e-29
Identities = 66/192 (34%), Positives = 113/192 (58%), Gaps = 5/192 (2%)
Frame = -1
Query: 607 YPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPP 428
+P +++PEFT+ E++L++G++DF G++HYT L+S Q + P+ + + ++
Sbjct: 90 HPVAQLPEFTEAEKQLLKGSADFLGLSHYTSRLISNAPQNTCIPSYDTIGGFS--QHVNH 147
Query: 427 EWPQSASYWLTLSPDSIYDTLTYLQKRYND---PIFYITENGWSSPPTNGLLDDD-RIRY 260
WPQ++S W+ + P I L ++ Y PI Y+ NG + L DD R+ Y
Sbjct: 148 VWPQTSSSWIRVVPWGIRRLLQFVSLEYTRGKVPI-YLAGNGMPIGESENLFDDSLRVDY 206
Query: 259 YRAALESVLDCL-DAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKS 83
+ + VL + + + ++ Y+A SL+D FE GY++RFGL+ V+FSD ++ RTPRKS
Sbjct: 207 FNQYINEVLKAIKEDSVDVRSYIARSLIDGFEGPSGYSQRFGLHHVNFSDSSKSRTPRKS 266
Query: 82 AFVYQGDLEKQG 47
A+ + +EK G
Sbjct: 267 AYFFTSIIEKNG 278
Score = 125 bits (301), Expect = 2e-28
Identities = 75/198 (37%), Positives = 102/198 (51%), Gaps = 2/198 (1%)
Frame = -1
Query: 634 VAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQISDRPTIPILPD 455
V +S + SR+P FT+EE+ +R +D F +N Y +V + P+ D
Sbjct: 604 VGNRSELQHLATSRLPSFTEEEKRFIRATADVFCLNTYYSRIVQHKTPRLNPPSYE--DD 661
Query: 454 ITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDD 275
+ P WP +A +P L ++++ Y D YITENG N D
Sbjct: 662 QEMAEEEDPSWPSTAMN--RAAPWGTRRLLNWIKEEYGDIPIYITENGVGLTNPN-TEDT 718
Query: 274 DRIRYYRAALESVLDC--LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARP 101
DRI Y++ + L LD GI L+GY+AWSLMDNFEWL GYT +FGLY VDF++ RP
Sbjct: 719 DRIFYHKTYINEALKAYRLD-GIDLRGYVAWSLMDNFEWLNGYTVKFGLYHVDFNNTNRP 777
Query: 100 RTPRKSAFVYQGDLEKQG 47
RT R SA Y + G
Sbjct: 778 RTARASARYYTEVITNNG 795
>Z84483-1|CAC94773.1| 739|Homo sapiens 46H23.1 (Klotho) protein.
Length = 739
Score = 81.0 bits (191), Expect = 3e-15
Identities = 44/121 (36%), Positives = 63/121 (52%), Gaps = 2/121 (1%)
Frame = -1
Query: 394 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 221
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 116 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 174
Query: 220 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQGHR 41
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA YQ +EK G
Sbjct: 175 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFP 234
Query: 40 P 38
P
Sbjct: 235 P 235
Score = 56.0 bits (129), Expect = 1e-07
Identities = 52/177 (29%), Positives = 83/177 (46%), Gaps = 8/177 (4%)
Frame = -1
Query: 592 IPEFTDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPE 425
+P FT++E++L++G DF ++HYT LV + ++ +D + + DIT
Sbjct: 513 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT-------- 564
Query: 424 WPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY--- 257
W S S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 565 WLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQ 619
Query: 256 RAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRK 86
E++ + GI L GY A+S D RFGLY +D P+ K
Sbjct: 620 NYINEALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMK 669
>AL161898-1|CAH71888.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 81.0 bits (191), Expect = 3e-15
Identities = 44/121 (36%), Positives = 63/121 (52%), Gaps = 2/121 (1%)
Frame = -1
Query: 394 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 221
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 220 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQGHR 41
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA YQ +EK G
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFP 507
Query: 40 P 38
P
Sbjct: 508 P 508
Score = 56.0 bits (129), Expect = 1e-07
Identities = 52/177 (29%), Positives = 83/177 (46%), Gaps = 8/177 (4%)
Frame = -1
Query: 592 IPEFTDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPE 425
+P FT++E++L++G DF ++HYT LV + ++ +D + + DIT
Sbjct: 786 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT-------- 837
Query: 424 WPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY--- 257
W S S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 838 WLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQ 892
Query: 256 RAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRK 86
E++ + GI L GY A+S D RFGLY +D P+ K
Sbjct: 893 NYINEALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMK 942
>AB009667-2|BAA24941.1| 549|Homo sapiens Klotho protein (KL)
protein.
Length = 549
Score = 81.0 bits (191), Expect = 3e-15
Identities = 44/121 (36%), Positives = 63/121 (52%), Gaps = 2/121 (1%)
Frame = -1
Query: 394 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 221
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 220 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQGHR 41
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA YQ +EK G
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFP 507
Query: 40 P 38
P
Sbjct: 508 P 508
>AB009667-1|BAA24940.1| 1012|Homo sapiens Klotho protein (KL)
protein.
Length = 1012
Score = 81.0 bits (191), Expect = 3e-15
Identities = 44/121 (36%), Positives = 63/121 (52%), Gaps = 2/121 (1%)
Frame = -1
Query: 394 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 221
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 220 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQGHR 41
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA YQ +EK G
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFP 507
Query: 40 P 38
P
Sbjct: 508 P 508
Score = 56.0 bits (129), Expect = 1e-07
Identities = 52/177 (29%), Positives = 83/177 (46%), Gaps = 8/177 (4%)
Frame = -1
Query: 592 IPEFTDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPE 425
+P FT++E++L++G DF ++HYT LV + ++ +D + + DIT
Sbjct: 786 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT-------- 837
Query: 424 WPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY--- 257
W S S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 838 WLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQ 892
Query: 256 RAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRK 86
E++ + GI L GY A+S D RFGLY +D P+ K
Sbjct: 893 NYINEALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMK 942
>AB005142-1|BAA23382.1| 1012|Homo sapiens klotho protein.
Length = 1012
Score = 81.0 bits (191), Expect = 3e-15
Identities = 44/121 (36%), Positives = 63/121 (52%), Gaps = 2/121 (1%)
Frame = -1
Query: 394 LSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYY--RAALESVLDCLD 221
L ++ L+++ +N P +I ENGW T DD + YY + +E++
Sbjct: 389 LESPNLRQLLSWIDLEFNHPQIFIVENGWFVSGTTKR-DDAKYMYYLKKFIMETLKAIKL 447
Query: 220 AGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQGHR 41
G+ + GY AWSLMD FEW GY+ R GL+ VDF + P+ SA YQ +EK G
Sbjct: 448 DGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKMLLPKSSALFYQKLIEKNGFP 507
Query: 40 P 38
P
Sbjct: 508 P 508
Score = 56.0 bits (129), Expect = 1e-07
Identities = 52/177 (29%), Positives = 83/177 (46%), Gaps = 8/177 (4%)
Frame = -1
Query: 592 IPEFTDEERELVRGASDFFGVNHYTGFLVSANEQ----ISDRPTIPILPDITVGNYIPPE 425
+P FT++E++L++G DF ++HYT LV + ++ +D + + DIT
Sbjct: 786 LPYFTEDEKKLIQGTFDFLALSHYTTILVDSEKEDPIKYNDYLEVQEMTDIT-------- 837
Query: 424 WPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSPPTNGL-LDDDRIRYY--- 257
W S S + + P + L +L+ +Y D YI NG +GL +DD++R Y
Sbjct: 838 WLNSPSQ-VAVVPWGLRKVLNWLKFKYGDLPMYIISNGID----DGLHAEDDQLRVYYMQ 892
Query: 256 RAALESVLDCLDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRK 86
E++ + GI L GY A+S D RFGLY +D P+ K
Sbjct: 893 NYINEALKAHILDGINLCGYFAYSFNDR------TAPRFGLYRY-AADQFEPKASMK 942
>BC113653-1|AAI13654.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 79.4 bits (187), Expect = 1e-14
Identities = 40/113 (35%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Frame = -1
Query: 382 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 206
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 205 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQG 47
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA Y+ + + G
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENG 507
Score = 58.8 bits (136), Expect = 2e-08
Identities = 59/183 (32%), Positives = 86/183 (46%), Gaps = 9/183 (4%)
Frame = -1
Query: 640 EIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQI------SDR 479
E +A K + G S +P T+ ER L++G DF +NH+T V +EQ+ SDR
Sbjct: 788 EYIASKH-RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDR 845
Query: 478 PTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSP 299
I L DIT S+ L + P + L ++++ Y D YIT +G
Sbjct: 846 D-IQFLQDIT---------RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID-- 893
Query: 298 PTNGLLDDDRIRYYRAA--LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYE 128
+ L+DDR+R Y L+ VL L +R+KGY A+ L + E RFG +
Sbjct: 894 --DQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFT 946
Query: 127 VDF 119
DF
Sbjct: 947 SDF 949
>BC104871-1|AAI04872.1| 1044|Homo sapiens klotho beta protein.
Length = 1044
Score = 79.4 bits (187), Expect = 1e-14
Identities = 40/113 (35%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Frame = -1
Query: 382 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 206
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 205 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQG 47
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA Y+ + + G
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENG 507
Score = 58.8 bits (136), Expect = 2e-08
Identities = 59/183 (32%), Positives = 86/183 (46%), Gaps = 9/183 (4%)
Frame = -1
Query: 640 EIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQI------SDR 479
E +A K + G S +P T+ ER L++G DF +NH+T V +EQ+ SDR
Sbjct: 788 EYIASKH-RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDR 845
Query: 478 PTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSP 299
I L DIT S+ L + P + L ++++ Y D YIT +G
Sbjct: 846 D-IQFLQDIT---------RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID-- 893
Query: 298 PTNGLLDDDRIRYYRAA--LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYE 128
+ L+DDR+R Y L+ VL L +R+KGY A+ L + E RFG +
Sbjct: 894 --DQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFT 946
Query: 127 VDF 119
DF
Sbjct: 947 SDF 949
>AB079373-1|BAC56857.1| 1044|Homo sapiens klotho beta like protein
protein.
Length = 1044
Score = 79.4 bits (187), Expect = 1e-14
Identities = 40/113 (35%), Positives = 60/113 (53%), Gaps = 1/113 (0%)
Frame = -1
Query: 382 SIYDTLTYLQKRYNDPIFYITENGWSSPPTNGLLDDDRIRYYRAALESVLDCLDAG-IRL 206
++ + L +++ YN+P I ENGW + D I + L VL + IR+
Sbjct: 395 NLREALNWIKLEYNNPRILIAENGWFTDSRVKTEDTTAIYMMKNFLSQVLQAIRLDEIRV 454
Query: 205 KGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQG 47
GY AWSL+D FEW + YT R GL+ VDF+ + R P+ SA Y+ + + G
Sbjct: 455 FGYTAWSLLDGFEWQDAYTIRRGLFYVDFNSKQKERKPKSSAHYYKQIIRENG 507
Score = 58.8 bits (136), Expect = 2e-08
Identities = 59/183 (32%), Positives = 86/183 (46%), Gaps = 9/183 (4%)
Frame = -1
Query: 640 EIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQI------SDR 479
E +A K + G S +P T+ ER L++G DF +NH+T V +EQ+ SDR
Sbjct: 788 EYIASKH-RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDR 845
Query: 478 PTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSP 299
I L DIT S+ L + P + L ++++ Y D YIT +G
Sbjct: 846 D-IQFLQDIT---------RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID-- 893
Query: 298 PTNGLLDDDRIRYYRAA--LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYE 128
+ L+DDR+R Y L+ VL L +R+KGY A+ L + E RFG +
Sbjct: 894 --DQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFT 946
Query: 127 VDF 119
DF
Sbjct: 947 SDF 949
>BC109377-1|AAI09378.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 73.7 bits (173), Expect = 5e-13
Identities = 31/56 (55%), Positives = 38/56 (67%)
Frame = -1
Query: 214 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQG 47
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y + G
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 157
>BC070188-1|AAH70188.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 73.7 bits (173), Expect = 5e-13
Identities = 31/56 (55%), Positives = 38/56 (67%)
Frame = -1
Query: 214 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQG 47
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y + G
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 157
>BC029362-1|AAH29362.1| 162|Homo sapiens GBA3 protein protein.
Length = 162
Score = 73.7 bits (173), Expect = 5e-13
Identities = 31/56 (55%), Positives = 38/56 (67%)
Frame = -1
Query: 214 IRLKGYMAWSLMDNFEWLEGYTERFGLYEVDFSDPARPRTPRKSAFVYQGDLEKQG 47
+ L+ Y AWSL+DNFEW +GY+ RFGL+ VDF DPARPR P SA Y + G
Sbjct: 102 VNLQVYCAWSLLDNFEWNQGYSSRFGLFHVDFEDPARPRVPYTSAKEYAKIIRNNG 157
>BC033021-1|AAH33021.1| 305|Homo sapiens KLB protein protein.
Length = 305
Score = 58.8 bits (136), Expect = 2e-08
Identities = 59/183 (32%), Positives = 86/183 (46%), Gaps = 9/183 (4%)
Frame = -1
Query: 640 EIVAEKSAKEGYPWSRIPEFTDEERELVRGASDFFGVNHYTGFLVSANEQI------SDR 479
E +A K + G S +P T+ ER L++G DF +NH+T V +EQ+ SDR
Sbjct: 49 EYIASKH-RRGLSSSALPRLTEAERRLLKGTVDFCALNHFTTRFVM-HEQLAGSRYDSDR 106
Query: 478 PTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIYDTLTYLQKRYNDPIFYITENGWSSP 299
I L DIT S+ L + P + L ++++ Y D YIT +G
Sbjct: 107 D-IQFLQDIT---------RLSSPTRLAVIPWGVRKLLRWVRRNYGDMDIYITASGID-- 154
Query: 298 PTNGLLDDDRIRYYRAA--LESVLDC-LDAGIRLKGYMAWSLMDNFEWLEGYTERFGLYE 128
+ L+DDR+R Y L+ VL L +R+KGY A+ L + E RFG +
Sbjct: 155 --DQALEDDRLRKYYLGKYLQEVLKAYLIDKVRIKGYYAFKLAE-----EKSKPRFGFFT 207
Query: 127 VDF 119
DF
Sbjct: 208 SDF 210
>U83246-1|AAC15920.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.29
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>CR456790-1|CAG33071.1| 537|Homo sapiens CPNE1 protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.29
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>BC001142-1|AAH01142.1| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.29
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-11|CAI20122.1| 386|Homo sapiens copine I protein.
Length = 386
Score = 34.7 bits (76), Expect = 0.29
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 288 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 341
>AL109827-10|CAO72111.1| 481|Homo sapiens copine I protein.
Length = 481
Score = 34.7 bits (76), Expect = 0.29
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AL109827-9|CAB87610.2| 537|Homo sapiens copine I protein.
Length = 537
Score = 34.7 bits (76), Expect = 0.29
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 312 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 365
>AB209827-1|BAD93064.1| 517|Homo sapiens copine I variant protein.
Length = 517
Score = 34.7 bits (76), Expect = 0.29
Identities = 16/54 (29%), Positives = 24/54 (44%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S + D + + P G +PP+W S + L +P + Y
Sbjct: 292 GVNEYLMALWSVGSVVQDYDSDKLFPAFGFGAQVPPDWQVSHEFALNFNPSNPY 345
>BC066597-1|AAH66597.1| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>BC036242-1|AAH36242.1| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>AF077226-1|AAD46074.2| 537|Homo sapiens copine III protein.
Length = 537
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 318 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 371
>AB014536-1|BAA31611.2| 540|Homo sapiens KIAA0636 protein protein.
Length = 540
Score = 32.7 bits (71), Expect = 1.2
Identities = 17/54 (31%), Positives = 23/54 (42%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSPDSIY 374
GVN Y L S I D + P G IPP+W S + + +P + Y
Sbjct: 321 GVNEYLTALWSVGLVIQDYDADKMFPAFGFGAQIPPQWQVSHEFPMNFNPSNPY 374
>BC053658-1|AAH53658.1| 548|Homo sapiens CPNE2 protein protein.
Length = 548
Score = 30.3 bits (65), Expect = 6.2
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 386
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 334 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 383
>AF542551-1|AAQ09534.1| 446|Homo sapiens unknown protein.
Length = 446
Score = 30.3 bits (65), Expect = 6.2
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 386
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 232 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 281
>AF492484-1|AAO85483.1| 548|Homo sapiens copine III-like related
protein protein.
Length = 548
Score = 30.3 bits (65), Expect = 6.2
Identities = 12/50 (24%), Positives = 23/50 (46%)
Frame = -1
Query: 535 GVNHYTGFLVSANEQISDRPTIPILPDITVGNYIPPEWPQSASYWLTLSP 386
G N Y + + + I D + + P + G +PP+W S + + +P
Sbjct: 334 GTNEYLSAIWAVGQIIQDYDSDKMFPALGFGAQLPPDWKVSHEFAINFNP 383
Database: human
Posted date: Oct 23, 2007 1:18 PM
Number of letters in database: 76,859,062
Number of sequences in database: 237,096
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.279 0.0580 0.190
Matrix: BLOSUM62
Gap Penalties: Existence: 9, Extension: 2
Number of Hits to DB: 98,176,127
Number of Sequences: 237096
Number of extensions: 2271242
Number of successful extensions: 5050
Number of sequences better than 10.0: 37
Number of HSP's better than 10.0 without gapping: 4796
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5005
length of database: 76,859,062
effective HSP length: 87
effective length of database: 56,231,710
effective search space used: 7197658880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 37 (14.9 bits)
X3: 62 (25.0 bits)
S1: 41 (21.7 bits)
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